Hub : Genes

Tnrc6b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Tnrc6b 0.08 0.05 5.6e-04 0.03 0.02 0.02 0.02 6.4e-04 2.6e-03 1.8e-03 1.7e-03
2 OFC gene expression Tnrc6b 0.19 0.11 1.4e-03 0.04 0.09 0.02 0.06 3.9e-02 4.5e-03 9.3e-02 1.6e-02
3 NAcc gene expression Tnrc6b 0.06 0.04 7.7e-05 0.04 0.03 0.04 0.04 3.9e-05 1.6e-04 1.8e-05 2.5e-05
4 PL gene expression Tnrc6b 0.08 0.04 7.6e-10 0.1 0.1 0.09 0.1 8.8e-11 8.1e-11 2.8e-10 1.1e-10
5 BLA gene expression Tnrc6b 0.23 0.11 3.0e-09 0.12 0.14 0.13 0.13 4.3e-07 7.6e-08 2.6e-07 1.6e-07
6 Liver gene expression Tnrc6b 0.09 0.05 3.2e-09 0.07 0.08 0.07 0.07 2.1e-08 7.3e-09 2.8e-08 4.0e-08
7 Brain gene expression Tnrc6b 0.23 0.1 0.0e+00 0.17 0.22 0.23 0.22 7.8e-16 1.8e-20 1.8e-21 2.3e-20
8 Liver mRNA stability Tnrc6b 0.07 0.05 1.2e-04 0.01 0.03 0.03 0.03 2.0e-02 2.7e-04 1.4e-04 1.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.10.20.7-0.6-0.20.1-0.3-0.4-0.40.30.8
Area under the delay curve0.60.71.8-0.8-0.20.8-0.7-1.2-0.21.3-0.6
BMI with tail0.51.74.52.1-1.60.5-1.1-0.2-1.60.31.5
BMI without tail0.20.41.9-0.0-0.2-0.60.20.3-0.7-0.71.4
Body weight0.72.89.03.0-2.21.1-1.6-0.4-1.60.81.1
Weight adjusted by age0.80.91.90.21.0-0.70.90.91.2-0.8-1.4
Bone surface0.20.40.9-0.4-0.30.8-0.7-0.8-0.11.00.1
Bone volume0.10.20.4-0.1-0.40.4-0.5-0.5-0.30.60.4
Breakpoint value in progressive ratio session0.30.30.8-0.5-0.40.1-0.4-0.6-0.70.40.9
Number of licking bursts0.40.41.1-1.00.80.10.5-0.10.8-0.0-0.8
Context. condit. distance diff. score1.92.39.73.1-0.1-1.00.72.00.5-1.5-0.5
Locomotion velocity, session 10.80.92.40.0-0.51.6-0.9-1.2-0.11.4-0.4
Locomotion distance, session 10.81.12.8-1.70.51.0-0.3-1.20.51.2-1.1
Locomotion velocity, session 20.30.30.50.4-0.70.7-0.7-0.5-0.50.50.5
Locomotion distance, session 21.62.25.0-2.1-0.51.6-1.3-2.2-0.81.90.4
Locomotion velocity, session 31.51.83.20.71.1-1.01.21.61.7-1.1-1.8
Locomotion distance, session 32.72.97.2-0.82.0-1.01.61.32.3-0.9-2.7
Stereotopy head waving bouts, day 31.41.72.51.1-1.61.3-1.5-1.2-1.41.11.2
Stereotopy head waving duration, day 32.22.74.32.0-2.11.4-1.7-0.9-1.81.01.8
Locomotion velocity, session 70.20.20.40.70.1-0.30.20.60.5-0.2-0.6
Locomotion distance, session 70.30.41.00.1-0.51.0-0.8-0.8-0.21.0-0.2
Stereotopy head waving bouts, day 70.50.62.91.7-0.3-0.40.11.00.1-0.70.1
Stereotopy head waving duration, day 71.01.32.81.60.2-1.30.81.70.4-1.50.1
Locomotion velocity, session 80.91.12.61.6-1.31.1-1.2-0.6-0.90.90.3
Locomotion distance, session 80.30.51.11.00.2-0.80.51.00.3-0.8-0.2
Degree of sensitization distance3.43.46.31.5-2.31.3-1.8-1.3-2.41.12.5
Degree of sensitization stereotypy0.91.02.11.40.3-0.90.71.50.7-1.2-0.6
Conditioned locomotion0.10.10.50.7-0.1-0.30.10.40.0-0.2-0.2
Cocaine response after cond. corrected0.20.20.30.3-0.50.5-0.5-0.4-0.40.60.3
Cocaine response after cond. not corrected0.10.10.30.0-0.20.0-0.2-0.1-0.30.10.5
Cocaine response before conditioning0.40.51.2-0.60.7-0.90.80.70.5-1.10.0
Saline control response1.52.03.5-0.41.5-1.91.61.61.3-1.6-0.9
Bone: connectivity density0.10.20.3-0.2-0.40.4-0.4-0.5-0.40.50.6
Bone: cortical apparent density1.21.52.9-0.91.5-0.71.21.01.7-0.8-1.6
Bone: cortical area1.62.43.61.6-1.91.6-1.7-1.2-1.61.41.2
Bone: cortical porosity0.70.82.70.9-1.00.1-0.7-0.2-1.20.11.6
Bone: cortical porosity1.51.63.51.4-1.60.6-1.2-0.6-1.60.61.9
Bone: cortical thickness0.60.91.20.8-1.11.1-1.1-1.0-0.91.10.5
Bone: cortical thickness1.41.62.60.6-1.31.6-1.5-1.5-1.21.50.3
Bone: cortical tissue density1.21.63.0-0.81.5-0.71.21.01.7-0.9-1.7
Condit. Reinf. active minus inactive responses0.10.10.3-0.40.00.5-0.2-0.50.20.4-0.2
Condit. Reinf. active-inactive response ratio0.20.20.50.50.3-0.10.30.50.6-0.3-0.7
Condit. Reinf. active responses0.40.52.6-1.60.8-0.30.5-0.10.5-0.20.0
Condit. Reinf. inactive responses1.01.25.6-2.41.2-1.00.90.10.5-0.70.2
Incentive salience index mean0.10.10.7-0.80.20.3-0.1-0.50.20.3-0.1
Condit. Reinf. lever presses0.20.21.6-1.30.20.0-0.1-0.4-0.00.10.3
Condit. Reinf. active minus inactive responses1.01.22.7-0.3-0.71.6-1.2-1.5-0.41.6-0.0
Condit. Reinf. active-inactive response ratio1.51.62.70.2-1.21.6-1.5-1.5-0.91.60.6
Condit. Reinf. active responses0.70.92.30.4-0.81.5-1.1-1.1-0.31.4-0.2
Condit. Reinf. inactive responses0.30.40.70.8-0.30.9-0.5-0.30.20.7-0.7
Condit. Reinf. lever presses0.10.20.7-0.80.00.2-0.2-0.5-0.10.40.2
Condit. Reinf. lever reinforcers received0.60.81.70.2-0.71.3-1.0-1.1-0.31.3-0.0
Conditioned reinforcement - actives0.50.51.40.40.10.9-0.2-0.50.50.9-1.2
Conditioned reinforcement - inactives0.91.02.5-0.9-0.61.2-0.9-1.6-0.81.30.6
Conditioned locomotion2.12.64.51.4-1.72.1-1.8-1.7-1.31.80.7
Patch foraging indifference point 0 sec0.20.41.2-1.0-0.20.0-0.3-0.6-0.60.41.1
Patch foraging indifference point AUC0.91.02.3-0.1-0.11.5-0.7-1.20.31.5-1.2
Delay disc. indifference point, 0s delay1.41.62.90.9-1.50.5-1.3-0.9-1.70.81.7
Delay disc. indifference point, 16s delay0.70.72.3-1.50.30.5-0.3-1.10.21.1-0.6
Delay disc. indifference point, 2s delay0.70.81.80.1-0.80.9-1.0-1.1-0.71.30.0
Delay disc. indifference point, 24s delay1.31.33.0-0.2-0.41.5-1.0-1.40.21.7-1.5
Delay disc. indifference point, 4s delay1.21.22.4-0.4-0.91.2-1.3-1.6-0.91.60.3
Delay disc. indifference point, 8s delay0.40.51.3-1.10.20.4-0.3-0.90.10.9-0.7
Indifference point function ln k0.71.02.41.20.1-1.20.71.60.2-1.40.4
Indifference point function log k0.71.02.41.20.1-1.20.71.60.2-1.40.4
Patch foraging total patch changes 0 sec0.30.51.3-1.1-0.2-0.0-0.3-0.7-0.70.41.1
Patch foraging total patch changes 12 sec0.40.51.00.1-0.60.9-0.8-1.0-0.61.00.3
Patch foraging total patch changes 18 sec2.02.64.7-0.3-1.41.9-1.7-2.2-1.51.91.3
Patch foraging total patch changes 24 sec0.30.30.8-0.7-0.10.4-0.5-0.9-0.30.90.0
Patch foraging total patch changes 6 sec1.82.65.5-0.8-1.31.6-1.8-2.3-1.62.11.0
Patch foraging time to switch 0 sec0.30.52.3-0.1-0.7-0.2-0.4-0.2-0.9-0.11.5
Patch foraging water rate 0 sec0.10.10.3-0.3-0.10.2-0.2-0.5-0.30.50.1
Patch foraging water rate 12 sec0.40.71.0-1.00.9-1.00.90.70.6-1.0-0.2
Patch foraging water rate 18 sec0.20.31.5-1.20.20.0-0.1-0.6-0.00.4-0.0
Patch foraging water rate 24 sec0.00.10.10.2-0.1-0.40.10.3-0.2-0.30.4
Patch foraging water rate 6 sec1.72.53.8-1.32.0-1.61.81.31.8-1.4-1.3
Seeking ratio, delayed vs. immediate footshock0.30.31.2-1.10.6-0.70.50.20.3-0.70.1
Distance traveled before self-admin0.20.20.7-0.1-0.30.5-0.3-0.6-0.50.40.8
Distance traveled after self-admin2.42.74.40.1-1.51.7-1.8-2.1-1.71.81.5
Extensor digitorum longus weight0.10.61.2-1.10.7-1.00.80.40.1-0.70.7
Bone: elastic displacement0.10.10.10.20.2-0.30.20.30.4-0.2-0.3
Bone: elastic work2.02.64.11.7-2.01.2-1.7-1.1-1.91.21.8
Bone: endosteal estimation0.81.72.71.1-1.61.4-1.5-1.1-1.31.11.2
Bone: endosteal perimeter0.61.23.11.8-1.50.8-1.1-0.3-1.10.51.0
Epididymis fat weight0.71.610.03.2-0.90.1-0.31.1-0.0-0.4-0.6
Delta time in closed arm before/after self-admin0.40.41.01.0-0.70.9-0.6-0.2-0.20.5-0.4
Delta time in open arm before/after self-admin0.20.20.9-0.90.3-0.30.3-0.1-0.1-0.30.6
Diff in mean of infusions in LGA sessions0.50.61.30.4-0.51.2-0.8-1.0-0.41.1-0.1
Delay discount exponential model param0.60.71.70.90.1-0.70.71.10.0-1.30.8
Extinction: sum of active levers before priming0.30.30.6-0.3-0.40.4-0.6-0.8-0.40.8-0.0
Active lever presses in extinction session 60.30.30.50.2-0.60.4-0.6-0.5-0.70.30.7
Bone: final force3.35.37.42.0-2.72.4-2.7-2.1-2.32.41.5
Bone: final moment3.65.98.22.1-2.92.6-2.8-2.2-2.42.61.6
Food consumed during 24 hour testing period2.12.64.01.8-2.01.6-1.8-1.3-1.81.31.1
Glucose0.20.31.1-0.8-0.1-0.5-0.0-0.1-0.5-0.21.1
Heart weight0.91.33.01.2-1.40.4-0.9-0.4-1.60.31.7
Delay discount hyperbolic model param0.70.71.90.70.3-0.80.81.20.2-1.40.5
Intermittent access intake day 1-15 change0.70.71.3-1.01.1-0.71.00.50.9-0.4-0.9
Intermittent access intake escalation0.60.61.1-1.01.0-0.70.90.40.8-0.4-0.6
Intermittent access intake escalation 20.20.20.6-0.80.6-0.50.50.20.3-0.2-0.1
Intermitt. access day 1 inactive lever presses1.11.22.10.3-1.20.9-1.1-1.1-1.40.91.4
Intermitt. access day 15 inactive lever presses0.91.01.80.3-0.91.3-1.1-1.3-0.81.20.2
Intermitt. access escalation Index0.00.00.1-0.30.2-0.20.20.00.0-0.10.1
Intermittent access day 1 total infusions1.61.83.50.9-1.51.9-1.5-1.4-1.21.40.8
Intermittent access day 15 total infusions0.50.61.3-0.4-0.51.1-0.7-1.1-0.51.10.2
Intermittent access terminal intake (last 3 days)0.20.20.7-0.2-0.10.8-0.3-0.6-0.10.60.0
Intermittent access total infusions1.51.73.20.4-1.31.8-1.4-1.5-1.21.40.9
Intermittent access day 1 locomotion1.41.52.30.6-1.31.5-1.2-1.2-1.31.11.3
Intermittent access day 15 total locomotion0.70.81.60.6-1.01.2-0.9-0.9-0.80.90.5
Intermittent access total locomotion2.02.33.90.9-1.72.0-1.6-1.5-1.51.41.3
Intermittent access standard deviation0.80.91.40.5-1.10.7-1.0-0.9-1.20.91.1
Left kidney weight3.08.337.86.1-3.42.4-2.6-0.2-1.71.50.1
Right kidney weight4.111.438.56.2-4.23.2-3.4-1.1-2.62.30.8
Cocaine induced anxiety0.81.02.01.4-1.40.3-1.0-0.2-1.30.31.1
Post-drug Anxiety0.50.51.00.6-1.00.3-0.8-0.3-1.00.30.9
Baseline Anxiety0.60.72.4-1.51.0-0.20.70.10.9-0.3-0.6
Tail length0.10.40.7-0.60.6-0.70.70.60.4-0.8-0.0
Length with tail0.10.42.21.5-0.70.5-0.50.1-0.10.3-0.3
Length without tail0.71.64.72.2-1.31.5-1.3-0.5-0.31.2-0.6
Times rat made contact with spout0.60.71.50.9-0.71.2-0.8-0.9-0.50.9-0.2
Lifetime Intake2.52.94.70.9-1.82.2-1.9-1.8-1.61.81.2
Liver weight, left0.50.71.71.30.3-0.50.61.20.7-1.0-0.7
Liver weight, right2.13.47.32.20.9-1.51.62.71.5-2.3-1.4
Locomotor activity0.40.62.31.5-0.90.6-0.6-0.0-0.60.10.6
Locomotor testing distance0.10.20.4-0.30.5-0.20.50.50.6-0.6-0.3
Locomotor testing rearing0.20.31.71.3-0.60.4-0.20.3-0.3-0.30.4
Locomotion in novel chamber4.65.78.6-2.12.9-2.72.82.12.4-2.2-1.6
Locomotion in novel chamber post-restriction0.50.61.0-0.81.0-0.71.00.60.8-0.8-0.4
Fecal boli incidents, locomotor time 11.61.73.3-0.7-1.01.6-1.4-1.8-1.21.60.9
Change in fecal boli incidents, locomotor task1.41.34.70.90.8-0.20.71.01.5-0.5-2.2
Time >=10cm from walls, locomotor time 10.90.91.70.6-1.11.3-1.0-0.9-1.00.71.0
Bouts of movement, locomotor time 10.50.52.21.5-0.70.6-0.7-0.2-0.20.5-0.5
Total resting periods, locomotor time 10.50.61.41.2-0.90.9-0.9-0.5-0.50.7-0.0
Rest time, locomotor task time 11.01.11.80.8-1.21.3-1.1-0.9-1.11.01.0
Distance moved, locomotor task time 10.60.61.30.40.6-1.10.81.10.6-1.0-0.4
Vertical activity count, locomotor time 10.00.00.2-0.1-0.1-0.4-0.1-0.0-0.3-0.10.2
Time >=10cm from walls, locomotor time 20.30.30.5-0.0-0.50.6-0.6-0.7-0.60.50.7
Bouts of movement, locomotor time 20.10.10.60.8-0.2-0.1-0.10.3-0.1-0.30.1
Total resting periods, locomotor time 20.20.20.40.7-0.50.4-0.4-0.2-0.40.20.2
Rest time, locomotor task time 20.20.30.8-0.3-0.20.9-0.4-0.60.00.8-0.2
Distance moved, locomotor task time 20.30.40.90.80.2-0.80.51.00.2-0.70.1
Vertical activity count, locomotor time 20.30.30.50.7-0.70.1-0.6-0.3-0.70.30.6
Light reinforcement 10.00.10.3-0.4-0.00.3-0.1-0.3-0.10.20.5
Light reinforcement 20.71.02.21.10.5-1.00.91.50.7-1.3-0.1
Bone: marrow area0.91.93.01.1-1.71.5-1.6-1.1-1.41.21.3
Bone: maximum diameter2.85.18.52.7-2.92.1-2.5-1.5-2.41.81.8
Bone: maximum force4.98.511.72.5-3.43.2-3.3-2.6-2.93.02.1
Bone: maximum moment5.39.112.52.6-3.53.4-3.4-2.7-3.03.12.2
Mean time between licks in bursts0.40.61.4-1.20.8-0.90.80.40.4-0.80.1
Mean num. licks in bursts0.60.83.51.9-1.00.6-0.7-0.1-0.70.40.1
Cd content in liver0.40.40.80.90.3-0.60.60.90.3-0.7-0.4
Co content in liver0.30.30.80.4-0.70.4-0.5-0.5-0.90.10.8
Cu content in liver0.80.95.4-2.30.9-0.70.6-0.30.4-0.10.2
Fe content in liver0.30.41.50.0-0.6-0.1-0.5-0.3-0.80.21.2
K content in liver0.10.10.8-0.90.1-0.2-0.1-0.4-0.10.30.3
Mg content in liver0.40.41.5-1.2-0.20.1-0.4-0.7-0.50.51.0
Mn content in liver0.60.71.70.40.7-0.60.70.91.1-0.6-1.3
Na content in liver0.60.63.5-1.90.6-0.50.4-0.20.1-0.20.5
Rb content in liver0.30.40.7-0.0-0.60.6-0.7-0.8-0.50.70.3
Se content in liver1.92.33.3-0.81.8-1.81.71.61.7-1.1-1.3
Sr content in liver1.41.32.0-1.01.4-1.21.40.91.1-1.0-1.1
Zn content in liver0.50.61.6-1.31.0-0.90.70.30.7-0.4-0.3
Bone: minimum diameter0.91.62.41.0-1.51.4-1.4-1.1-1.31.11.3
Time in familiar zone, hab. session 10.90.81.70.2-0.71.3-1.0-1.1-0.41.3-0.4
Time in novel zone, hab. session 10.60.61.40.60.2-1.00.70.9-0.2-1.20.8
Total zone transitions, hab. session 12.43.45.8-2.32.4-1.01.70.82.4-0.6-2.4
Total locomotion distance, hab. session 12.43.46.4-1.82.4-1.21.81.22.5-1.0-2.2
Locomotion velocity, hab. session 11.72.44.5-2.02.0-0.91.40.72.1-0.5-1.8
Time in familiar zone, hab. session 21.51.52.0-0.11.3-1.21.41.41.4-1.3-1.3
Time in novel zone, hab. session 21.31.31.70.1-1.21.1-1.2-1.3-1.31.21.1
Total zone transitions, hab. session 20.91.22.6-1.2-0.31.4-0.9-1.6-0.31.5-0.1
Total locomotion distance, hab. session 20.50.61.8-1.4-0.10.7-0.5-1.2-0.40.90.4
Locomotion velocity, hab. session 20.70.93.0-1.7-0.00.7-0.6-1.4-0.31.10.4
Novel to familiar place preference ratio0.40.42.71.7-0.3-0.00.00.6-0.1-0.4-0.1
Novelty place preference0.70.73.92.0-0.2-0.10.20.90.1-0.6-0.5
Time in novel zone, NPP test0.80.85.02.2-0.40.00.10.80.0-0.5-0.5
Total zone transitions, NPP test1.62.25.1-2.31.8-0.31.10.01.90.1-2.2
Total locomotion distance, NPP test0.60.82.7-1.61.00.10.4-0.31.00.4-1.1
Locomotion velocity, NPP test0.81.24.2-2.01.3-0.30.7-0.11.20.1-1.2
Intraocular pressure0.20.31.01.0-0.20.5-0.20.20.40.2-0.7
Delta distance traveled before/after self-admin0.91.01.60.8-1.01.3-1.2-1.1-0.71.20.0
Delta ambulatory time before/after self-admin1.61.82.90.7-1.41.7-1.6-1.6-1.11.60.3
Parametrial fat weight0.00.10.50.7-0.1-0.00.00.20.0-0.1-0.2
Pavlov. Cond. lever latency0.20.31.61.3-0.50.5-0.3-0.1-0.30.3-0.0
Pavlov. Cond. magazine entry latency0.30.30.8-0.9-0.20.5-0.4-0.9-0.40.60.2
Pavlov. Cond. change in total contacts1.11.12.5-1.3-0.61.1-1.0-1.6-0.81.20.6
Pavlov. Cond. index score0.20.30.6-0.6-0.30.5-0.5-0.7-0.40.60.3
Pavlov. Cond. latency score0.10.10.4-0.6-0.20.2-0.3-0.5-0.30.30.3
Pavlov. Cond. lever contacts0.20.31.8-1.30.3-0.20.1-0.30.0-0.00.2
Pavlov. Cond. magazine entry number0.10.10.40.6-0.1-0.40.10.4-0.1-0.40.4
Pavlov. Cond. intertrial magazine entries0.50.71.9-1.4-0.10.7-0.5-1.2-0.40.90.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.5-0.7-0.10.3-0.3-0.6-0.10.40.0
Pavlov. Cond. response bias0.20.30.8-0.9-0.20.4-0.4-0.7-0.30.50.2
Pavlov. Cond. lever latency0.40.52.41.5-0.20.5-0.10.30.40.2-1.0
Pavlov. Cond. magazine entry latency1.01.23.5-1.9-0.30.5-0.7-1.5-0.91.01.0
Pavlov. Cond. change in total contacts2.23.14.8-1.0-1.61.4-1.9-2.2-2.01.72.0
Pavlov. Cond. index score0.50.73.3-1.8-0.00.1-0.3-1.0-0.50.50.8
Pavlov. Cond. latency score0.70.83.9-2.0-0.10.2-0.4-1.1-0.60.60.8
Pavlov. Cond. lever contacts0.30.52.2-1.50.2-0.60.2-0.2-0.3-0.30.9
Pavlov. Cond. magazine entry number0.50.61.61.30.3-0.40.61.10.6-0.7-0.6
Pavlov. Cond. intertrial magazine entries0.71.02.81.7-1.11.3-0.9-0.5-0.70.70.3
Pavlov. Cond. lever-magazine prob. diff.0.50.73.3-1.8-0.0-0.0-0.3-0.9-0.50.40.9
Pavlov. Cond. response bias0.50.71.9-1.4-0.40.1-0.5-0.9-0.90.41.2
Time in closed arm before self-admin1.72.05.2-2.2-0.4-0.2-0.6-1.4-1.50.82.3
Time in closed arm after self-admin1.31.32.00.7-1.41.0-1.3-1.0-1.41.01.3
Time in open arm before self-admin1.31.42.40.71.1-0.71.21.41.5-1.0-1.5
Time in open arm after self-admin1.41.62.4-0.71.4-1.61.51.31.2-1.4-0.7
Bone: periosteal estimation1.63.45.21.7-2.31.9-2.1-1.5-1.91.51.7
Bone: periosteal perimeter1.83.06.32.5-2.21.5-1.8-0.9-1.71.21.5
Bone: post-yield work3.04.17.60.4-2.02.8-2.2-2.4-1.82.31.4
Progressive ratio test 1 active lever presses2.22.34.20.8-1.52.0-1.7-1.8-1.31.80.8
Progressive ratio test 1 breakpoint1.11.22.80.6-1.01.7-1.1-1.3-0.71.30.4
Progressive ratio test 1 inactive lever presses1.31.42.80.3-1.11.1-1.1-1.3-1.40.91.7
Progressive ratio test 2 active lever presses0.70.82.00.1-0.51.4-0.9-1.1-0.21.2-0.6
Progressive ratio test 2 breakpoint1.01.12.50.3-0.91.6-1.2-1.3-0.51.4-0.2
Progressive ratio test 2 inactive lever presses0.50.61.4-0.7-0.31.0-0.7-1.2-0.41.00.2
Incentive Sensitization - Responses0.50.51.3-0.70.8-0.40.60.40.9-0.3-1.1
Incentive Sensitization - Breakpoint0.40.41.3-0.50.6-0.30.50.40.8-0.2-1.1
Sum of active levers in priming session hrs 5-60.10.10.5-0.40.0-0.20.1-0.1-0.3-0.10.7
Progressive ratio0.40.41.1-0.3-0.40.5-0.5-0.8-0.70.61.0
Food seeking constrained by brief footshock0.60.71.21.1-0.91.0-0.9-0.7-0.60.80.2
Seeking ratio, punishment vs. effort0.20.20.40.7-0.50.5-0.5-0.2-0.20.4-0.3
Retroperitoneal fat weight0.93.119.54.4-1.60.8-0.90.9-0.4-0.1-0.1
Reaction time number correct2.02.84.4-0.91.9-1.61.71.62.1-1.2-2.1
Reaction time mean minus median0.10.10.3-0.10.1-0.40.20.2-0.2-0.50.3
Reaction time mean minus median AUC0.30.30.90.70.0-0.70.40.8-0.1-0.90.2
Reaction time num false alarms0.20.20.6-0.40.4-0.80.60.50.1-0.60.2
Reaction time num false alarms AUC0.30.50.7-0.70.7-0.80.80.70.5-0.7-0.2
Reaction time trials correct on left2.02.84.4-0.91.9-1.61.71.62.1-1.2-2.1
Reaction time trials on left2.13.04.6-0.92.0-1.61.81.62.1-1.2-2.2
Reaction time mean0.20.30.7-0.60.2-0.60.50.4-0.1-0.80.6
Reaction time mean AUC0.20.20.6-0.60.3-0.50.50.40.1-0.80.3
Median of all reaction times0.20.30.7-0.90.3-0.50.40.3-0.1-0.70.6
Reaction time omissions0.40.50.7-0.80.9-0.60.80.50.7-0.7-0.7
Reaction time false alarm rate0.10.10.7-0.1-0.2-0.20.10.1-0.4-0.30.8
Reaction time premature initiation rate1.41.82.9-0.5-1.41.0-1.5-1.5-1.61.31.7
Reaction time premature initiations0.20.30.5-0.6-0.50.3-0.6-0.7-0.50.70.5
Std. dev. reaction times0.10.10.50.1-0.0-0.30.30.4-0.2-0.70.4
Reaction time trials completed2.13.04.6-0.92.0-1.61.81.62.1-1.2-2.2
Reaction time trials AUC1.52.23.6-0.71.7-1.41.51.41.9-1.0-1.9
Run reversals in cocaine runway, females1.41.31.8-0.91.3-1.01.21.01.3-1.2-1.1
Run reversals in cocaine runway, males0.60.62.21.00.00.9-0.10.10.70.5-1.5
Latency to leave start box in cocaine runway0.50.51.40.90.2-0.90.61.20.3-1.0-0.2
Latency to leave start box in cocaine runway, F0.30.40.8-0.10.5-0.80.70.80.5-0.9-0.2
Latency to leave start box in cocaine runway, M0.50.52.11.5-0.3-0.60.11.0-0.1-0.5-0.1
Std. dev. time between licks in bursts0.50.62.6-1.6-0.20.3-0.5-1.0-0.50.60.7
Total sessions with >9 infusions2.52.74.91.5-1.92.2-1.8-1.5-1.51.51.0
Short access day 1 total inactive lever presses4.34.87.40.2-2.22.6-2.5-2.7-2.22.41.8
Short access day 10 total inactive lever presses0.10.10.10.1-0.30.3-0.3-0.3-0.30.20.3
Short access day 1 total infusions1.21.31.90.9-1.31.4-1.2-1.1-1.10.91.0
Short access day 10 total infusions3.03.34.71.6-2.22.1-2.0-1.6-1.91.61.6
Short access total infusions3.84.36.21.7-2.42.5-2.2-1.9-2.11.81.7
Short access day 1 locomotion0.70.71.80.2-0.80.9-0.7-0.9-1.00.41.3
Short access day 10 total locomotion0.50.63.5-0.2-0.30.3-0.1-0.4-0.90.01.9
Short access total locomotion2.62.74.51.3-1.71.8-1.5-1.4-1.81.12.1
One hour access (0.3 mA shock)0.20.20.5-0.70.20.5-0.1-0.60.10.5-0.2
Compulsive drug intake1.31.33.8-1.31.4-0.30.80.01.50.1-1.9
One hour access (shock baseline)0.20.20.80.3-0.50.4-0.3-0.2-0.60.10.9
Social response proportion0.70.83.80.1-0.7-0.2-0.3-0.2-1.3-0.31.9
Social responses0.10.20.4-0.4-0.10.6-0.3-0.6-0.20.50.1
Social time0.40.63.3-1.80.50.10.2-0.7-0.10.20.6
Soleus weight0.20.51.1-0.80.10.8-0.4-0.90.11.0-0.6
Bone: stiffness3.96.28.71.8-2.92.5-2.8-2.3-2.72.32.3
Tibialis anterior weight0.10.52.3-1.50.2-0.0-0.1-0.9-0.40.50.6
Time to tail flick, vehicle, before self-admin0.20.20.50.2-0.30.5-0.5-0.6-0.20.7-0.4
Time to tail flick, vehicle, after self-admin0.50.61.1-1.10.8-0.70.80.60.7-0.8-0.5
Time to tail flick, test, before self-admin0.10.10.60.10.30.10.20.20.5-0.1-0.7
Time to tail flick, test, after self-admin0.50.51.4-1.20.9-0.80.70.10.5-0.4-0.3
Delta time to tail flick, vehicle, before/after SA0.20.20.5-0.70.2-0.40.30.2-0.1-0.60.7
Delta time to tail flick, test, before/after SA1.21.02.9-1.71.2-1.31.00.40.7-0.7-0.2
Tibia length0.82.23.71.8-1.61.9-1.7-1.2-0.91.60.1
Ambulatory time before self-admin0.10.10.3-0.60.3-0.00.2-0.20.10.00.1
Ambulatory time after self-admin1.01.12.6-0.8-0.61.2-1.0-1.6-0.81.30.6
Bone: tissue strength0.10.10.20.4-0.20.3-0.3-0.10.00.40.0
Total heroin consumption0.40.50.90.3-0.70.9-0.9-0.8-0.50.9-0.2
Bone: trabecular number0.30.40.70.30.6-0.60.70.90.7-0.6-0.4
Bone: trabecular spacing2.73.55.21.1-2.12.3-2.2-2.0-1.82.10.9
Bone: trabecular thickness0.60.71.6-0.50.7-1.30.91.00.5-1.20.2
Bone: trabecular tissue density0.40.62.5-1.60.1-0.50.1-0.4-0.6-0.11.2
Water consumed over 24 hours0.81.01.91.1-1.01.4-1.0-1.0-0.80.90.0
Number of responses in last shaping day2.93.04.4-0.8-1.71.4-1.9-2.1-2.01.81.8