Hub : Genes

Tmem177

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Tmem177 0.53 0.17 0.0e+00 0.25 0.3 0.3 0.31 7.7e-27 1.1e-32 1.7e-33 2.4e-34
2 OFC gene expression Tmem177 0.63 0.16 1.4e-10 0.28 0.26 0.27 0.27 2.3e-07 7.6e-07 3.4e-07 4.5e-07
3 IL gene expression Tmem177 0.56 0.17 5.5e-08 0.17 0.14 0.13 0.12 7.2e-05 3.1e-04 5.6e-04 6.7e-04
4 BLA gene expression Tmem177 0.22 0.12 4.7e-06 0.06 0.06 0.04 0.05 2.9e-04 6.8e-04 3.1e-03 1.4e-03
5 Liver gene expression Tmem177 0.06 0.04 2.4e-05 0.03 0.03 0.02 0.03 1.7e-04 3.3e-04 3.6e-03 3.0e-04
6 Adipose gene expression Tmem177 0.05 0.03 3.4e-04 0.01 0.01 0 0.01 9.9e-03 3.9e-02 2.0e-01 2.4e-02
7 NAcc gene expression Tmem177 0.19 0.11 4.1e-10 0.04 0.05 0.04 0.04 4.4e-06 1.3e-07 2.5e-06 6.6e-07
8 IC gene expression Tmem177 0.28 0.12 4.7e-07 0.05 0.1 0.08 0.08 4.3e-03 7.3e-05 3.7e-04 2.3e-04
9 Brain gene expression Tmem177 0.22 0.09 6.1e-16 0.07 0.14 0.13 0.14 9.6e-07 1.2e-12 3.4e-12 1.4e-12
10 pVTA gene expression Tmem177 0.13 0.07 2.4e-05 0.01 0.04 0.03 0.03 2.0e-02 4.6e-04 1.4e-03 1.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.40.81.4-0.6-0.5-0.7-0.70.70.9-1.1-0.9-1.1-1.2
Area under the delay curve5.66.59.13.02.93.03.0-2.9-2.72.01.91.91.6
BMI with tail2.37.810.32.72.52.82.7-2.6-2.43.23.13.02.9
BMI without tail1.34.14.81.81.82.02.1-2.0-1.92.22.22.12.1
Body weight1.25.46.42.42.42.52.5-2.4-2.22.22.32.12.0
Weight adjusted by age1.62.43.41.51.61.41.4-1.4-1.81.61.71.61.6
Bone surface0.00.10.2-0.00.10.00.0-0.00.10.30.50.40.5
Bone volume0.00.00.10.10.30.10.1-0.10.1-0.3-0.1-0.2-0.3
Breakpoint value in progressive ratio session0.70.81.31.11.11.01.0-1.0-1.10.70.70.70.6
Number of licking bursts0.10.10.20.40.30.40.4-0.4-0.50.20.10.20.2
Context. condit. distance diff. score0.20.20.30.30.30.50.4-0.5-0.40.60.40.50.5
Locomotion velocity, session 15.15.56.72.12.22.42.5-2.4-2.62.22.22.42.3
Locomotion distance, session 11.82.23.11.61.61.81.6-1.8-1.71.21.21.21.0
Locomotion velocity, session 22.63.04.82.22.12.02.0-2.0-2.11.11.21.10.8
Locomotion distance, session 20.91.21.91.41.41.31.2-1.3-1.30.60.70.60.4
Locomotion velocity, session 30.00.00.1-0.1-0.20.10.0-0.1-0.0-0.2-0.3-0.2-0.2
Locomotion distance, session 30.10.20.4-0.6-0.6-0.4-0.50.40.4-0.3-0.1-0.2-0.1
Stereotopy head waving bouts, day 30.50.61.0-0.7-0.8-0.7-0.60.70.6-1.0-0.9-0.9-1.0
Stereotopy head waving duration, day 30.10.10.3-0.3-0.3-0.3-0.20.30.3-0.4-0.6-0.4-0.3
Locomotion velocity, session 70.50.61.1-1.0-0.8-0.9-1.00.90.9-0.2-0.5-0.20.1
Locomotion distance, session 70.00.00.1-0.3-0.2-0.1-0.20.10.1-0.1-0.2-0.1-0.0
Stereotopy head waving bouts, day 70.40.41.0-0.3-0.5-0.6-0.40.60.5-0.7-0.8-0.9-1.0
Stereotopy head waving duration, day 70.00.00.10.0-0.1-0.10.00.10.1-0.1-0.2-0.2-0.2
Locomotion velocity, session 80.10.20.5-0.4-0.4-0.3-0.40.30.3-0.4-0.7-0.4-0.4
Locomotion distance, session 80.10.20.40.50.50.60.5-0.6-0.60.30.20.20.1
Degree of sensitization distance0.20.20.40.50.60.50.5-0.5-0.50.30.20.30.3
Degree of sensitization stereotypy0.80.81.7-0.5-0.7-0.8-0.70.80.7-1.0-1.1-1.2-1.3
Conditioned locomotion0.10.10.20.30.40.40.4-0.4-0.40.10.10.20.2
Cocaine response after cond. corrected0.60.72.00.40.30.60.6-0.6-0.51.20.91.21.4
Cocaine response after cond. not corrected0.80.92.20.50.40.80.7-0.8-0.81.20.81.31.5
Cocaine response before conditioning0.10.10.3-0.2-0.2-0.1-0.10.10.0-0.5-0.5-0.4-0.4
Saline control response0.10.20.5-0.2-0.20.00.1-0.0-0.1-0.6-0.6-0.6-0.7
Bone: connectivity density0.91.32.2-1.2-1.1-1.3-1.31.31.5-0.9-0.8-1.0-0.9
Bone: cortical apparent density2.02.74.4-1.5-1.5-1.3-1.31.31.3-1.8-1.9-2.0-2.1
Bone: cortical area0.91.31.8-1.1-1.0-1.1-1.11.11.1-1.3-1.3-1.2-1.2
Bone: cortical porosity0.10.10.2-0.5-0.5-0.4-0.40.40.4-0.3-0.0-0.00.0
Bone: cortical porosity0.00.00.1-0.2-0.10.00.0-0.0-0.0-0.00.20.20.3
Bone: cortical thickness1.62.72.9-1.7-1.6-1.6-1.61.61.6-1.7-1.7-1.6-1.6
Bone: cortical thickness3.64.35.0-1.9-1.8-2.0-2.02.02.0-2.2-2.2-2.2-2.2
Bone: cortical tissue density1.62.23.9-1.3-1.3-1.1-1.11.11.2-1.6-1.8-1.9-2.0
Condit. Reinf. active minus inactive responses0.00.00.10.20.10.20.3-0.2-0.30.00.30.10.1
Condit. Reinf. active-inactive response ratio0.40.40.5-0.6-0.7-0.7-0.60.70.6-0.7-0.7-0.6-0.6
Condit. Reinf. active responses0.40.40.70.60.50.70.7-0.7-0.80.60.80.60.5
Condit. Reinf. inactive responses0.50.60.90.60.60.80.7-0.8-0.80.81.00.70.7
Incentive salience index mean0.00.00.00.1-0.10.00.1-0.0-0.1-0.10.2-0.0-0.1
Condit. Reinf. lever presses0.00.00.0-0.0-0.2-0.1-0.10.10.00.00.2-0.1-0.1
Condit. Reinf. active minus inactive responses3.54.68.01.71.61.71.7-1.7-1.82.62.62.72.8
Condit. Reinf. active-inactive response ratio5.56.48.82.22.12.22.2-2.2-2.32.92.92.93.0
Condit. Reinf. active responses3.54.97.52.02.01.81.8-1.8-1.92.62.62.62.7
Condit. Reinf. inactive responses0.10.10.3-0.1-0.0-0.5-0.50.50.5-0.2-0.0-0.1-0.0
Condit. Reinf. lever presses0.50.70.90.70.80.90.9-0.9-0.90.70.90.90.9
Condit. Reinf. lever reinforcers received3.65.07.22.12.01.91.9-1.9-2.02.52.62.62.7
Conditioned reinforcement - actives0.10.20.40.40.40.60.6-0.6-0.40.20.20.30.3
Conditioned reinforcement - inactives0.10.20.3-0.3-0.5-0.5-0.40.50.5-0.4-0.4-0.5-0.5
Conditioned locomotion0.60.81.7-0.6-0.7-0.6-0.50.81.2-0.7-1.0-1.2-1.3
Patch foraging indifference point 0 sec1.12.13.6-1.4-1.2-1.1-1.21.00.8-1.9-1.9-1.7-1.8
Patch foraging indifference point AUC0.30.51.01.01.00.90.8-0.8-0.60.50.40.20.1
Delay disc. indifference point, 0s delay1.21.32.11.41.41.41.4-1.3-1.20.80.80.60.4
Delay disc. indifference point, 16s delay8.39.111.33.02.93.33.1-3.4-3.22.82.82.92.8
Delay disc. indifference point, 2s delay0.30.30.70.70.80.40.6-0.3-0.2-0.4-0.5-0.5-0.7
Delay disc. indifference point, 24s delay1.31.42.31.51.51.51.3-1.5-1.50.60.80.60.4
Delay disc. indifference point, 4s delay3.94.16.12.52.52.42.4-2.4-2.11.51.41.41.1
Delay disc. indifference point, 8s delay2.83.35.12.32.22.22.1-2.1-1.91.41.21.21.0
Indifference point function ln k0.00.00.1-0.2-0.3-0.2-0.20.1-0.10.00.10.30.4
Indifference point function log k0.00.00.1-0.2-0.3-0.2-0.20.1-0.10.00.10.30.4
Patch foraging total patch changes 0 sec0.71.32.5-1.1-0.9-0.7-0.90.60.5-1.6-1.6-1.4-1.5
Patch foraging total patch changes 12 sec1.11.53.3-0.6-0.5-0.7-0.80.80.8-1.6-1.7-1.7-1.8
Patch foraging total patch changes 18 sec1.01.52.6-1.0-0.8-0.9-1.01.00.9-1.6-1.6-1.5-1.6
Patch foraging total patch changes 24 sec0.50.91.4-0.9-0.7-0.7-0.60.90.9-1.1-1.2-1.0-1.0
Patch foraging total patch changes 6 sec0.71.12.3-0.8-0.7-0.5-0.70.60.8-1.3-1.5-1.4-1.5
Patch foraging time to switch 0 sec0.20.30.70.50.50.50.6-0.4-0.20.80.60.70.7
Patch foraging water rate 0 sec0.40.91.6-1.0-0.9-0.9-1.00.90.6-1.3-1.2-0.9-0.8
Patch foraging water rate 12 sec0.51.01.6-1.0-1.1-1.3-1.21.11.1-0.7-0.7-0.8-0.7
Patch foraging water rate 18 sec0.71.11.5-1.0-1.0-1.1-1.11.01.1-1.0-1.2-1.1-1.0
Patch foraging water rate 24 sec0.00.00.1-0.0-0.0-0.1-0.10.0-0.3-0.1-0.00.20.2
Patch foraging water rate 6 sec1.21.72.2-1.2-1.3-1.4-1.51.41.5-1.3-1.2-1.2-1.1
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.3-0.1-0.2-0.20.30.5-0.2-0.4-0.2-0.1
Distance traveled before self-admin0.10.20.30.60.60.50.5-0.5-0.20.50.2-0.0-0.1
Distance traveled after self-admin1.62.02.2-1.4-1.5-1.4-1.41.41.4-1.3-1.3-1.5-1.4
Extensor digitorum longus weight0.10.51.00.80.80.80.7-0.8-0.7-0.5-0.4-0.7-1.0
Bone: elastic displacement0.00.00.1-0.1-0.0-0.2-0.10.20.2-0.00.00.10.1
Bone: elastic work1.52.02.4-1.4-1.3-1.4-1.31.41.4-1.5-1.6-1.5-1.4
Bone: endosteal estimation0.10.20.30.40.50.50.5-0.5-0.50.30.30.40.4
Bone: endosteal perimeter0.40.81.31.11.10.80.9-0.8-0.90.70.80.80.8
Epididymis fat weight1.86.19.82.42.42.12.0-2.0-1.93.12.92.72.8
Delta time in closed arm before/after self-admin0.00.00.10.0-0.00.10.1-0.10.20.3-0.10.20.3
Delta time in open arm before/after self-admin1.01.01.81.11.21.31.2-1.3-1.40.20.40.0-0.3
Diff in mean of infusions in LGA sessions0.60.71.0-1.0-0.8-1.0-0.91.00.8-0.7-0.8-0.6-0.5
Delay discount exponential model param5.15.67.9-2.8-2.8-2.8-2.72.72.5-1.8-1.8-1.8-1.5
Extinction: sum of active levers before priming0.10.10.2-0.1-0.3-0.4-0.30.40.2-0.3-0.1-0.2-0.1
Active lever presses in extinction session 60.30.30.50.60.60.70.6-0.6-0.60.10.3-0.0-0.2
Bone: final force0.71.11.5-1.1-1.1-0.9-0.90.90.9-1.2-1.1-1.1-1.1
Bone: final moment0.61.01.4-1.1-1.0-0.8-0.80.80.8-1.2-1.1-1.0-1.1
Food consumed during 24 hour testing period0.30.50.80.70.70.80.8-0.8-0.90.50.70.60.5
Glucose4.97.89.42.92.82.62.6-2.6-2.63.13.02.92.9
Heart weight0.00.10.3-0.1-0.0-0.1-0.20.10.50.40.20.00.1
Delay discount hyperbolic model param4.55.07.4-2.7-2.7-2.6-2.62.62.4-1.7-1.6-1.6-1.3
Intermittent access intake day 1-15 change0.40.81.8-1.1-1.3-1.2-1.31.10.9-0.3-0.2-0.20.1
Intermittent access intake escalation1.02.23.8-1.8-1.9-1.9-2.01.71.5-0.9-0.8-0.8-0.5
Intermittent access intake escalation 21.11.22.1-1.3-1.5-1.4-1.41.31.2-0.6-0.7-0.6-0.3
Intermitt. access day 1 inactive lever presses0.10.41.2-0.2-0.2-0.4-0.30.5-0.1-1.1-0.6-0.8-0.9
Intermitt. access day 15 inactive lever presses0.10.10.3-0.5-0.5-0.3-0.40.50.2-0.20.1-0.00.0
Intermitt. access escalation Index0.00.10.30.00.00.20.10.0-0.1-0.3-0.2-0.4-0.5
Intermittent access day 1 total infusions0.10.20.3-0.5-0.4-0.2-0.30.40.5-0.5-0.6-0.4-0.4
Intermittent access day 15 total infusions1.92.94.1-1.9-2.0-1.8-2.01.81.8-1.4-1.4-1.4-1.2
Intermittent access terminal intake (last 3 days)1.11.52.2-1.4-1.5-1.2-1.41.21.3-1.0-1.1-1.0-0.9
Intermittent access total infusions0.70.81.3-1.1-1.1-0.8-1.00.91.0-0.7-0.7-0.7-0.6
Intermittent access day 1 locomotion0.50.61.7-0.5-0.5-0.3-0.40.40.6-0.9-1.1-1.2-1.3
Intermittent access day 15 total locomotion0.30.61.0-0.6-0.5-0.6-0.60.61.0-0.7-1.0-0.9-1.0
Intermittent access total locomotion0.50.60.8-0.7-0.8-0.7-0.70.70.8-0.7-0.8-0.9-0.9
Intermittent access standard deviation0.20.41.1-0.9-1.1-0.7-0.90.70.3-0.3-0.2-0.00.2
Left kidney weight1.15.19.43.03.12.92.9-2.9-2.30.80.80.3-0.3
Right kidney weight1.04.58.92.93.02.72.6-2.6-2.40.50.80.4-0.2
Cocaine induced anxiety0.60.81.80.60.50.50.5-0.6-0.61.21.31.21.3
Post-drug Anxiety0.20.20.5-0.4-0.5-0.4-0.40.20.10.50.60.60.7
Baseline Anxiety0.40.50.7-0.9-0.8-0.7-0.70.60.5-0.9-0.6-0.7-0.6
Tail length0.00.00.2-0.1-0.0-0.2-0.00.0-0.2-0.4-0.2-0.2-0.3
Length with tail0.20.71.51.11.21.01.1-1.0-1.00.30.40.30.2
Length without tail0.10.30.60.70.80.70.6-0.6-0.40.20.00.1-0.0
Times rat made contact with spout0.80.91.2-1.0-1.0-0.8-0.80.80.9-1.1-1.0-1.0-1.0
Lifetime Intake0.40.50.8-0.9-0.9-0.6-0.80.70.8-0.6-0.7-0.7-0.6
Liver weight, left0.00.10.20.40.30.10.1-0.1-0.1-0.20.1-0.2-0.3
Liver weight, right0.30.61.21.11.01.00.9-1.0-0.80.20.30.20.0
Locomotor activity2.84.36.02.42.32.32.4-2.3-2.21.71.81.61.4
Locomotor testing distance2.44.35.82.42.32.42.4-2.4-2.31.61.81.61.3
Locomotor testing rearing0.50.91.61.31.31.21.2-1.2-1.20.50.60.40.2
Locomotion in novel chamber1.31.72.1-1.2-1.4-1.2-1.21.31.1-1.4-1.3-1.4-1.4
Locomotion in novel chamber post-restriction0.10.10.1-0.1-0.3-0.2-0.20.30.3-0.2-0.3-0.3-0.3
Fecal boli incidents, locomotor time 11.21.83.51.21.41.21.3-1.0-0.81.91.61.41.5
Change in fecal boli incidents, locomotor task4.03.94.9-2.2-2.2-2.1-2.11.81.7-2.2-1.7-1.8-1.8
Time >=10cm from walls, locomotor time 10.30.30.6-0.7-0.6-0.6-0.70.80.6-0.1-0.2-0.3-0.2
Bouts of movement, locomotor time 11.01.11.81.31.31.31.2-1.2-1.00.80.80.70.6
Total resting periods, locomotor time 10.80.91.61.21.31.11.0-1.0-0.80.80.80.70.6
Rest time, locomotor task time 10.91.22.00.81.00.90.9-1.0-0.71.21.31.41.4
Distance moved, locomotor task time 10.10.20.60.1-0.10.0-0.00.0-0.2-0.6-0.7-0.6-0.8
Vertical activity count, locomotor time 11.12.54.2-1.2-1.3-1.4-1.41.41.4-1.6-1.9-2.0-2.0
Time >=10cm from walls, locomotor time 21.21.83.3-1.6-1.4-1.8-1.71.81.7-0.4-0.5-0.6-0.3
Bouts of movement, locomotor time 22.03.24.42.01.82.11.9-2.0-2.11.31.51.61.5
Total resting periods, locomotor time 22.34.15.62.22.12.42.2-2.2-2.31.51.71.81.6
Rest time, locomotor task time 21.21.52.01.01.11.31.3-1.4-1.41.11.31.21.2
Distance moved, locomotor task time 20.20.20.60.0-0.2-0.3-0.30.30.1-0.6-0.6-0.7-0.8
Vertical activity count, locomotor time 20.30.40.6-0.6-0.6-0.6-0.60.80.7-0.4-0.6-0.7-0.7
Light reinforcement 10.71.72.71.41.41.61.5-1.6-1.40.91.20.90.8
Light reinforcement 20.20.30.5-0.3-0.4-0.3-0.40.40.40.60.70.50.7
Bone: marrow area0.00.10.20.30.30.30.4-0.3-0.40.10.20.30.2
Bone: maximum diameter0.00.00.10.20.3-0.00.10.0-0.0-0.2-0.2-0.2-0.2
Bone: maximum force0.91.62.3-1.3-1.3-1.0-1.01.01.0-1.5-1.5-1.4-1.4
Bone: maximum moment0.81.32.0-1.2-1.1-0.9-0.90.90.9-1.4-1.4-1.2-1.3
Mean time between licks in bursts0.81.93.5-1.5-1.6-1.9-1.81.91.9-0.2-0.7-0.4-0.0
Mean num. licks in bursts0.50.81.0-1.0-0.9-0.9-0.80.91.0-0.9-0.7-0.8-0.8
Cd content in liver0.10.10.10.30.30.30.3-0.3-0.30.30.20.20.2
Co content in liver5.46.210.0-3.0-3.1-3.1-3.03.03.2-1.3-1.5-1.2-0.8
Cu content in liver8.49.911.1-3.2-3.1-3.0-3.03.03.0-3.3-3.2-3.3-3.2
Fe content in liver0.70.91.6-1.3-1.3-1.0-1.01.01.1-0.6-0.8-0.6-0.5
K content in liver0.00.00.10.30.20.00.1-0.1-0.10.10.20.10.1
Mg content in liver0.10.10.2-0.3-0.4-0.4-0.40.40.4-0.00.0-0.10.0
Mn content in liver0.00.00.20.10.10.20.0-0.20.0-0.1-0.1-0.3-0.4
Na content in liver1.92.03.61.31.20.91.1-0.8-0.71.91.81.71.9
Rb content in liver1.82.14.0-1.7-1.7-1.9-1.81.92.0-0.5-0.7-0.4-0.0
Se content in liver0.10.10.20.20.10.30.3-0.3-0.20.40.40.40.4
Sr content in liver1.71.52.11.11.11.11.1-1.1-1.11.31.41.31.3
Zn content in liver0.00.00.10.10.10.1-0.0-0.1-0.2-0.00.1-0.2-0.2
Bone: minimum diameter0.10.10.3-0.6-0.5-0.3-0.30.30.3-0.5-0.3-0.2-0.2
Time in familiar zone, hab. session 10.10.10.2-0.3-0.2-0.4-0.40.40.40.2-0.00.20.4
Time in novel zone, hab. session 10.30.30.5-0.6-0.5-0.4-0.50.40.4-0.6-0.4-0.6-0.7
Total zone transitions, hab. session 10.20.20.40.60.50.60.5-0.6-0.60.30.40.30.2
Total locomotion distance, hab. session 10.20.30.60.70.80.80.6-0.8-0.70.00.10.0-0.1
Locomotion velocity, hab. session 10.20.30.50.70.70.70.6-0.7-0.7-0.2-0.1-0.1-0.3
Time in familiar zone, hab. session 20.10.10.4-0.5-0.4-0.4-0.20.40.30.3-0.10.40.6
Time in novel zone, hab. session 20.20.20.30.60.50.50.4-0.5-0.4-0.10.2-0.2-0.4
Total zone transitions, hab. session 20.00.00.00.10.10.10.1-0.1-0.20.00.20.10.1
Total locomotion distance, hab. session 20.20.30.50.70.60.70.6-0.7-0.7-0.20.1-0.1-0.2
Locomotion velocity, hab. session 20.10.10.20.50.50.40.3-0.4-0.4-0.4-0.1-0.3-0.4
Novel to familiar place preference ratio1.21.42.01.31.21.41.3-1.4-1.30.91.10.80.6
Novelty place preference1.01.11.71.11.01.31.2-1.3-1.20.71.00.60.5
Time in novel zone, NPP test1.21.31.91.21.11.41.3-1.4-1.30.91.20.80.7
Total zone transitions, NPP test0.30.41.10.30.20.40.3-0.4-0.40.90.90.91.0
Total locomotion distance, NPP test0.00.10.10.10.10.30.1-0.3-0.3-0.3-0.1-0.2-0.4
Locomotion velocity, NPP test0.00.10.20.00.00.1-0.0-0.1-0.1-0.4-0.2-0.3-0.4
Intraocular pressure0.10.20.30.30.30.50.5-0.4-0.40.50.40.30.3
Delta distance traveled before/after self-admin1.92.03.0-1.6-1.7-1.6-1.61.61.2-1.4-1.2-1.1-1.0
Delta ambulatory time before/after self-admin1.21.42.2-1.4-1.5-1.3-1.31.30.8-1.3-1.0-0.9-0.8
Parametrial fat weight1.74.16.91.71.61.41.5-1.5-1.82.52.62.52.6
Pavlov. Cond. lever latency0.00.00.0-0.10.10.10.1-0.10.0-0.0-0.10.10.1
Pavlov. Cond. magazine entry latency0.20.20.5-0.4-0.5-0.7-0.70.70.70.1-0.1-0.10.1
Pavlov. Cond. change in total contacts0.00.00.0-0.0-0.2-0.1-0.20.10.10.10.20.10.1
Pavlov. Cond. index score0.20.20.5-0.4-0.6-0.7-0.70.70.6-0.1-0.2-0.2-0.0
Pavlov. Cond. latency score0.10.10.2-0.2-0.4-0.5-0.50.50.40.10.00.00.1
Pavlov. Cond. lever contacts0.20.30.4-0.3-0.6-0.6-0.60.60.5-0.4-0.4-0.5-0.5
Pavlov. Cond. magazine entry number0.60.71.30.81.01.11.1-1.1-1.10.40.50.50.3
Pavlov. Cond. intertrial magazine entries0.40.40.70.70.60.80.7-0.8-0.70.40.60.60.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.3-0.3-0.4-0.5-0.50.50.50.0-0.1-0.1-0.0
Pavlov. Cond. response bias0.30.40.6-0.5-0.7-0.8-0.80.80.7-0.3-0.4-0.4-0.3
Pavlov. Cond. lever latency1.01.42.1-1.3-1.4-1.3-1.51.31.4-0.7-0.9-0.8-0.7
Pavlov. Cond. magazine entry latency0.10.20.4-0.6-0.6-0.3-0.30.30.4-0.4-0.4-0.3-0.2
Pavlov. Cond. change in total contacts0.40.60.80.80.80.80.8-0.8-0.90.70.90.80.7
Pavlov. Cond. index score0.20.20.40.50.50.60.6-0.6-0.60.20.30.30.2
Pavlov. Cond. latency score0.00.00.10.10.10.20.2-0.2-0.2-0.2-0.0-0.1-0.1
Pavlov. Cond. lever contacts1.41.92.81.51.51.61.7-1.6-1.60.91.11.00.8
Pavlov. Cond. magazine entry number0.00.10.1-0.2-0.1-0.3-0.30.30.3-0.1-0.1-0.1-0.0
Pavlov. Cond. intertrial magazine entries0.50.71.70.50.60.50.4-0.5-0.51.11.11.21.3
Pavlov. Cond. lever-magazine prob. diff.0.20.20.40.50.50.60.7-0.6-0.70.20.30.30.2
Pavlov. Cond. response bias1.01.42.11.31.31.41.5-1.4-1.40.71.00.80.7
Time in closed arm before self-admin1.31.72.0-1.3-1.3-1.4-1.41.41.4-1.1-1.1-1.2-1.2
Time in closed arm after self-admin2.82.95.2-1.8-1.8-1.8-1.71.82.3-1.1-1.8-1.5-1.4
Time in open arm before self-admin1.11.22.30.91.10.81.0-0.8-1.01.01.11.41.5
Time in open arm after self-admin1.51.62.21.31.51.51.5-1.4-1.50.81.11.00.8
Bone: periosteal estimation0.00.00.10.00.10.10.1-0.1-0.1-0.3-0.3-0.1-0.2
Bone: periosteal perimeter0.00.10.10.40.30.20.2-0.2-0.30.30.20.30.4
Bone: post-yield work0.10.10.4-0.3-0.20.0-0.0-0.0-0.00.50.40.50.6
Progressive ratio test 1 active lever presses0.00.00.1-0.00.10.30.1-0.2-0.10.10.0-0.0-0.1
Progressive ratio test 1 breakpoint0.00.00.1-0.00.10.30.1-0.2-0.10.10.10.0-0.0
Progressive ratio test 1 inactive lever presses0.20.30.60.10.20.60.4-0.5-0.8-0.7-0.3-0.5-0.8
Progressive ratio test 2 active lever presses0.60.71.2-0.8-0.8-0.6-0.80.50.8-1.1-1.1-0.9-0.9
Progressive ratio test 2 breakpoint0.70.81.3-0.9-0.9-0.6-0.80.50.9-1.1-1.2-1.0-1.0
Progressive ratio test 2 inactive lever presses1.83.03.7-1.7-1.9-1.6-1.81.41.5-1.9-1.8-1.8-1.8
Incentive Sensitization - Responses0.20.20.5-0.5-0.5-0.4-0.50.10.5-0.7-0.6-0.3-0.3
Incentive Sensitization - Breakpoint0.30.30.7-0.6-0.6-0.5-0.60.20.6-0.8-0.7-0.5-0.5
Sum of active levers in priming session hrs 5-60.20.20.3-0.3-0.4-0.4-0.40.40.1-0.5-0.4-0.5-0.5
Progressive ratio0.10.10.40.00.10.20.3-0.2-0.0-0.6-0.6-0.4-0.5
Food seeking constrained by brief footshock0.10.20.5-0.2-0.2-0.1-0.20.10.3-0.7-0.6-0.5-0.6
Seeking ratio, punishment vs. effort0.10.10.30.0-0.0-0.1-0.20.10.10.50.50.40.5
Retroperitoneal fat weight3.414.328.92.82.62.52.6-2.6-2.65.04.85.05.4
Reaction time number correct0.20.40.50.60.60.70.7-0.7-0.70.50.60.60.6
Reaction time mean minus median0.51.22.10.80.81.00.8-0.9-1.01.41.31.31.4
Reaction time mean minus median AUC0.20.61.60.30.30.50.3-0.4-0.51.21.01.11.3
Reaction time num false alarms0.91.32.3-1.2-1.2-1.5-1.51.31.1-1.0-0.9-0.7-0.5
Reaction time num false alarms AUC0.20.30.7-0.7-0.6-0.8-0.80.60.4-0.6-0.5-0.4-0.3
Reaction time trials correct on left0.20.40.50.60.60.70.7-0.7-0.70.50.60.60.6
Reaction time trials on left0.20.40.50.60.50.70.7-0.7-0.70.50.60.60.6
Reaction time mean0.00.10.1-0.3-0.3-0.4-0.40.40.3-0.00.0-0.2-0.1
Reaction time mean AUC0.00.00.1-0.2-0.2-0.2-0.20.20.10.20.20.10.1
Median of all reaction times0.20.30.5-0.6-0.6-0.7-0.60.70.6-0.4-0.3-0.5-0.5
Reaction time omissions0.30.40.8-0.9-0.8-0.8-0.80.80.6-0.3-0.5-0.4-0.3
Reaction time false alarm rate0.60.81.4-1.0-0.9-1.2-1.21.00.8-0.7-0.7-0.6-0.4
Reaction time premature initiation rate0.10.10.4-0.1-0.10.2-0.2-0.3-0.20.30.60.40.4
Reaction time premature initiations0.10.30.60.20.20.50.2-0.6-0.50.50.80.60.6
Std. dev. reaction times0.00.10.3-0.0-0.00.1-0.0-0.0-0.10.50.50.40.5
Reaction time trials completed0.20.40.50.60.50.70.7-0.7-0.70.50.60.60.6
Reaction time trials AUC0.20.30.50.50.50.70.6-0.7-0.60.50.50.60.5
Run reversals in cocaine runway, females4.94.95.72.12.12.32.2-2.4-2.02.32.02.32.3
Run reversals in cocaine runway, males0.70.71.2-0.9-1.0-1.1-1.11.01.1-0.5-0.6-0.5-0.3
Latency to leave start box in cocaine runway0.10.20.4-0.1-0.3-0.4-0.40.40.70.60.40.20.3
Latency to leave start box in cocaine runway, F0.20.30.80.40.30.20.2-0.1-0.10.90.60.70.7
Latency to leave start box in cocaine runway, M0.40.30.9-0.5-0.6-0.7-0.70.60.9-0.4-0.2-0.5-0.5
Std. dev. time between licks in bursts0.20.20.4-0.5-0.6-0.6-0.50.60.60.30.00.30.5
Total sessions with >9 infusions0.30.40.7-0.7-0.6-0.6-0.60.50.4-0.8-0.7-0.7-0.8
Short access day 1 total inactive lever presses0.10.10.2-0.4-0.5-0.2-0.20.10.1-0.4-0.3-0.4-0.4
Short access day 10 total inactive lever presses1.94.66.32.01.91.91.9-2.0-2.52.02.42.32.3
Short access day 1 total infusions0.10.10.1-0.4-0.3-0.4-0.40.30.1-0.3-0.2-0.10.0
Short access day 10 total infusions0.40.50.8-0.7-0.6-0.5-0.60.50.7-0.7-0.9-0.9-0.9
Short access total infusions0.10.10.1-0.3-0.3-0.1-0.20.20.3-0.2-0.3-0.3-0.3
Short access day 1 locomotion0.10.10.3-0.3-0.2-0.3-0.20.2-0.5-0.5-0.0-0.1-0.1
Short access day 10 total locomotion0.10.30.4-0.4-0.5-0.5-0.60.50.1-0.6-0.6-0.6-0.6
Short access total locomotion0.20.30.5-0.7-0.7-0.6-0.60.50.0-0.6-0.3-0.4-0.4
One hour access (0.3 mA shock)0.10.10.20.30.30.30.3-0.30.20.40.10.10.1
Compulsive drug intake2.42.95.32.32.31.92.1-1.6-1.61.41.31.10.8
One hour access (shock baseline)2.03.14.7-2.2-2.1-1.9-2.01.71.9-1.5-1.6-1.3-1.1
Social response proportion1.01.22.5-1.1-1.1-1.5-1.41.51.60.1-0.4-0.20.1
Social responses0.10.10.3-0.3-0.4-0.6-0.50.60.40.0-0.2-0.00.1
Social time0.40.61.2-0.8-0.9-1.1-1.01.00.9-0.1-0.3-0.00.3
Soleus weight0.20.72.7-0.1-0.00.1-0.0-0.1-0.0-1.2-1.0-1.3-1.7
Bone: stiffness0.30.40.6-0.7-0.6-0.4-0.60.40.4-0.8-0.8-0.7-0.8
Tibialis anterior weight0.41.42.01.31.21.41.3-1.4-1.30.91.00.90.8
Time to tail flick, vehicle, before self-admin0.10.10.20.30.30.20.2-0.2-0.3-0.3-0.0-0.3-0.4
Time to tail flick, vehicle, after self-admin0.10.10.30.40.30.40.2-0.3-0.2-0.1-0.2-0.4-0.5
Time to tail flick, test, before self-admin6.06.38.5-2.5-2.4-2.6-2.62.62.9-2.3-2.3-2.4-2.3
Time to tail flick, test, after self-admin1.81.92.7-1.6-1.6-1.6-1.71.61.6-0.9-1.0-1.0-0.8
Delta time to tail flick, vehicle, before/after SA0.10.10.10.40.40.30.2-0.3-0.30.20.10.0-0.0
Delta time to tail flick, test, before/after SA3.63.74.91.71.61.81.7-1.7-2.02.12.12.22.2
Tibia length0.20.51.10.50.50.50.6-0.5-0.60.60.81.01.1
Ambulatory time before self-admin0.10.20.40.60.60.60.5-0.6-0.20.50.20.10.0
Ambulatory time after self-admin2.02.43.1-1.7-1.7-1.6-1.71.61.7-1.2-1.3-1.4-1.3
Bone: tissue strength0.20.20.5-0.7-0.7-0.5-0.50.50.50.30.10.20.4
Total heroin consumption0.50.61.11.01.10.90.9-0.9-0.7-0.3-0.3-0.4-0.6
Bone: trabecular number0.50.92.3-0.5-0.4-0.6-0.60.60.8-1.2-1.1-1.4-1.5
Bone: trabecular spacing2.02.64.81.21.21.31.3-1.3-1.42.01.82.12.2
Bone: trabecular thickness7.49.311.3-2.8-2.7-2.8-2.92.83.0-3.4-3.1-3.3-3.3
Bone: trabecular tissue density1.31.92.8-1.3-1.4-1.1-1.11.11.0-1.6-1.7-1.6-1.6
Water consumed over 24 hours0.10.20.5-0.2-0.3-0.1-0.10.10.0-0.7-0.5-0.6-0.7
Number of responses in last shaping day1.01.11.8-1.1-1.1-0.9-1.00.80.6-1.4-1.1-1.0-1.1