Thrsp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	Thrsp	0.07	0.04	5.8e-05	0.03	0.03	0.02	0.03	1.3e-04	6.1e-04	1.3e-03	8.6e-04
2	Brain	gene expression	Thrsp	0.22	0.09	0.0e+00	0.24	0.24	0.23	0.24	3.6e-22	4.6e-22	1.7e-21	2.6e-22
3	RMTg	gene expression	Thrsp	0.13	0.08	2.3e-03	0.07	0.07	0.04	0.06	5.6e-03	7.4e-03	3.2e-02	1.0e-02
4	pVTA	gene expression	Thrsp	0.23	0.1	5.6e-17	0.18	0.2	0.2	0.19	2.6e-14	4.8e-16	9.8e-16	4.8e-15
5	NAcc	gene expression	Thrsp	0.04	0.02	6.2e-07	0.05	0.04	0.04	0.04	1.4e-07	4.1e-07	1.6e-06	2.7e-07
6	Liver	mRNA stability	Thrsp	0.13	0.09	5.5e-06	0.06	0.04	0.05	0.05	6.1e-07	8.2e-06	3.9e-06	2.3e-06
7	BLA	gene expression	Thrsp	0.1	0.06	1.5e-04	0.09	0.07	0.07	0.07	3.1e-05	1.1e-04	1.9e-04	8.6e-05
8	PL	gene expression	Thrsp	0.17	0.1	1.1e-16	0.16	0.16	0.17	0.16	1.4e-16	2.5e-17	3.9e-18	1.3e-17
9	Adipose	gene expression	Thrsp	0.4	0.14	0.0e+00	0.18	0.18	0.18	0.18	1.8e-19	2.7e-19	4.3e-19	4.9e-20
10	IL	gene expression	Thrsp	0.38	0.15	2.3e-05	0.1	0.12	0.18	0.1	2.5e-03	8.3e-04	3.3e-05	2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.1	0.1	0.3	-0.2	0.4	0.1	0.2	-0.3	-0.3	0.3	-0.5	0.4	-0.1
Area under the delay curve	0.7	0.9	1.4	-1.2	-1.0	-0.9	-1.0	0.8	1.1	-0.9	1.0	-0.8	0.7
BMI with tail	0.5	1.6	12.0	3.5	0.7	0.5	1.5	-0.3	-0.3	0.3	0.1	0.7	-0.6
BMI without tail	0.5	1.6	13.3	3.6	0.3	0.2	1.4	0.0	0.3	0.2	0.4	0.2	-0.5
Body weight	0.7	3.2	21.9	4.7	1.1	0.9	2.3	-0.6	-0.1	0.4	-0.3	1.4	-0.8
Weight adjusted by age	0.2	0.3	0.8	0.4	-0.4	-0.5	-0.4	0.7	-0.5	-0.6	0.6	-0.9	-0.0
Bone surface	1.3	2.3	3.4	-1.2	-1.6	-1.8	-1.8	1.8	0.8	-1.8	1.5	-1.7	1.0
Bone volume	0.7	1.3	2.0	-0.6	-1.2	-1.4	-1.2	1.3	0.8	-1.3	1.1	-1.3	0.7
Breakpoint value in progressive ratio session	0.3	0.4	0.7	-0.2	0.8	0.7	0.5	-0.8	-0.6	0.6	-0.5	0.7	-0.5
Number of licking bursts	1.9	3.0	4.4	1.9	1.9	1.8	2.0	-1.8	-1.3	1.7	-1.6	2.1	-1.1
Context. condit. distance diff. score	3.0	3.6	5.7	-2.2	-2.0	-2.0	-2.4	2.0	0.8	-2.0	1.7	-2.1	1.2
Locomotion velocity, session 1	0.4	0.5	2.7	-1.6	-0.6	-0.3	-0.8	0.2	0.4	-0.3	0.2	-0.7	0.3
Locomotion distance, session 1	0.3	0.4	0.9	-0.8	-0.9	-0.6	-0.9	0.4	0.1	-0.6	0.8	-0.6	0.4
Locomotion velocity, session 2	0.7	0.9	1.5	-0.9	-0.9	-0.8	-1.0	0.8	0.9	-1.0	1.0	-1.2	0.5
Locomotion distance, session 2	0.1	0.1	0.6	0.1	-0.1	0.1	0.2	-0.1	0.8	0.0	-0.1	0.1	0.1
Locomotion velocity, session 3	0.3	0.3	0.6	-0.7	-0.5	-0.5	-0.6	0.5	0.5	-0.5	0.4	-0.6	0.3
Locomotion distance, session 3	1.8	1.9	3.7	-1.9	-1.4	-1.4	-1.7	1.4	0.8	-1.3	1.2	-1.5	0.9
Stereotopy head waving bouts, day 3	3.5	4.1	5.1	2.0	2.3	2.1	2.1	-2.1	-2.1	2.1	-2.0	1.8	-1.6
Stereotopy head waving duration, day 3	0.3	0.4	0.7	0.3	0.7	0.6	0.9	-0.7	0.3	0.7	-0.7	0.8	-0.2
Locomotion velocity, session 7	0.3	0.3	0.8	-0.9	-0.5	-0.4	-0.7	0.6	0.3	-0.5	-0.0	-0.5	0.4
Locomotion distance, session 7	0.9	1.1	1.8	-0.8	-1.2	-1.2	-1.3	1.3	0.5	-1.2	0.7	-1.1	0.8
Stereotopy head waving bouts, day 7	0.1	0.1	0.8	-0.9	0.1	0.1	-0.4	0.0	-0.2	-0.0	-0.2	-0.4	-0.1
Stereotopy head waving duration, day 7	0.2	0.2	0.5	-0.7	-0.4	-0.3	-0.6	0.4	0.4	-0.4	0.4	-0.6	0.2
Locomotion velocity, session 8	5.9	7.1	12.2	-3.5	-2.7	-2.5	-3.0	2.7	2.7	-2.7	1.8	-2.5	2.0
Locomotion distance, session 8	1.5	2.2	3.0	-1.7	-1.6	-1.5	-1.7	1.5	1.2	-1.6	1.2	-1.6	1.0
Degree of sensitization distance	0.2	0.2	2.1	1.4	-0.0	0.1	0.4	-0.0	-0.3	0.0	-0.1	0.2	-0.2
Degree of sensitization stereotypy	1.4	1.5	3.5	-1.9	-1.1	-1.1	-1.6	1.2	0.3	-1.1	0.9	-1.5	0.6
Conditioned locomotion	0.1	0.2	0.7	-0.5	0.3	0.3	0.3	-0.4	0.8	0.2	-0.2	0.4	0.0
Cocaine response after cond. corrected	0.2	0.2	0.5	0.2	-0.4	-0.3	-0.4	0.4	-0.5	-0.5	0.7	-0.3	0.1
Cocaine response after cond. not corrected	0.2	0.2	0.9	-0.1	-0.3	-0.2	-0.5	0.3	-1.0	-0.4	0.5	-0.2	0.0
Cocaine response before conditioning	0.5	0.6	2.0	-0.3	0.8	0.8	0.3	-0.8	-1.4	0.8	-0.9	0.6	-0.5
Saline control response	0.5	0.7	2.9	0.1	-0.9	-1.0	-0.2	0.8	1.7	-0.7	0.8	-0.2	0.8
Bone: connectivity density	0.2	0.3	1.5	-1.2	-0.2	-0.4	-0.7	0.3	-0.6	-0.3	0.1	-0.4	0.1
Bone: cortical apparent density	0.2	0.3	0.6	0.4	0.6	0.6	0.7	-0.7	0.2	0.6	-0.7	0.7	-0.2
Bone: cortical area	0.4	0.6	1.1	0.5	-0.9	-0.9	-0.7	1.0	0.3	-1.0	0.7	-0.6	0.5
Bone: cortical porosity	0.2	0.2	0.7	-0.1	0.4	0.4	0.1	-0.4	-0.8	0.4	-0.5	0.3	-0.3
Bone: cortical porosity	0.3	0.3	1.0	-0.1	0.5	0.5	0.2	-0.6	-1.0	0.6	-0.6	0.2	-0.4
Bone: cortical thickness	0.1	0.2	0.5	0.7	0.2	0.3	0.3	-0.2	-0.7	0.2	-0.5	0.5	-0.2
Bone: cortical thickness	0.7	0.9	1.5	-0.3	-1.2	-1.0	-1.2	1.0	-0.3	-1.0	1.1	-1.1	0.4
Bone: cortical tissue density	0.3	0.4	0.5	0.3	0.6	0.7	0.7	-0.7	0.2	0.6	-0.7	0.7	-0.3
Condit. Reinf. active minus inactive responses	0.2	0.2	1.1	1.0	-0.4	-0.4	0.1	0.3	0.5	-0.3	0.4	-0.1	0.1
Condit. Reinf. active-inactive response ratio	0.2	0.2	1.3	1.1	-0.2	-0.3	0.3	0.2	0.4	-0.2	0.3	0.1	0.1
Condit. Reinf. active responses	0.1	0.1	0.9	1.0	-0.0	0.1	0.4	-0.1	0.3	0.1	0.0	0.2	-0.2
Condit. Reinf. inactive responses	0.0	0.0	0.1	0.0	0.1	0.2	0.1	-0.2	0.0	0.2	-0.0	-0.1	-0.2
Incentive salience index mean	0.3	0.4	0.6	0.5	-0.8	-0.8	-0.4	0.7	0.6	-0.7	0.8	-0.7	0.3
Condit. Reinf. lever presses	0.7	0.9	1.6	-0.9	-1.1	-1.0	-1.1	1.0	0.8	-1.0	0.9	-1.3	0.5
Condit. Reinf. active minus inactive responses	4.4	5.7	8.3	-0.7	-2.9	-2.8	-2.3	2.7	2.3	-2.7	2.8	-2.3	1.7
Condit. Reinf. active-inactive response ratio	2.5	2.9	4.0	-0.8	-2.0	-2.0	-1.7	1.9	1.6	-1.8	2.0	-1.6	1.2
Condit. Reinf. active responses	5.2	7.3	10.2	-0.4	-3.2	-3.1	-2.4	3.1	2.7	-3.1	3.2	-2.6	1.9
Condit. Reinf. inactive responses	0.9	1.1	1.9	0.6	-1.1	-1.1	-0.6	1.2	1.3	-1.2	1.4	-1.0	0.7
Condit. Reinf. lever presses	11.0	15.2	20.3	-2.5	-4.4	-4.3	-3.7	4.2	4.5	-4.2	4.1	-3.4	3.1
Condit. Reinf. lever reinforcers received	6.0	8.4	11.8	-0.7	-3.4	-3.4	-2.7	3.3	2.8	-3.3	3.4	-2.8	2.0
Conditioned reinforcement - actives	0.7	1.1	2.3	-1.4	-0.8	-1.1	-1.5	1.2	-0.2	-1.2	0.7	-1.3	0.4
Conditioned reinforcement - inactives	0.4	0.6	1.6	-0.4	1.3	0.8	0.4	-0.7	-1.1	0.5	-0.9	0.8	-0.3
Conditioned locomotion	1.2	1.6	5.3	-2.3	-0.7	-1.1	-1.8	1.2	-0.6	-1.2	0.5	-1.4	0.5
Patch foraging indifference point 0 sec	1.1	2.0	3.8	-0.7	-1.6	-1.6	-1.2	1.4	1.9	-1.6	1.5	-1.0	1.1
Patch foraging indifference point AUC	0.3	0.4	0.8	-0.0	-0.8	-0.7	-0.6	0.6	0.4	-0.6	0.9	-0.8	0.3
Delay disc. indifference point, 0s delay	0.9	1.0	2.0	-0.3	-1.0	-1.0	-1.2	1.1	-0.4	-1.0	1.3	-1.4	0.4
Delay disc. indifference point, 16s delay	0.5	0.6	2.7	-1.2	-0.7	-0.5	-0.4	0.3	1.6	-0.3	0.7	-0.1	0.6
Delay disc. indifference point, 2s delay	0.7	0.8	1.2	-0.9	-0.7	-1.0	-1.1	1.0	0.2	-1.0	1.0	-1.1	0.5
Delay disc. indifference point, 24s delay	0.2	0.2	1.4	-0.3	-0.0	0.1	0.4	-0.4	1.2	0.2	-0.5	0.6	0.1
Delay disc. indifference point, 4s delay	2.3	2.4	3.6	-0.8	-1.5	-1.8	-1.6	1.8	1.1	-1.8	1.9	-1.7	1.0
Delay disc. indifference point, 8s delay	0.7	0.9	1.7	-1.2	-1.1	-0.8	-0.9	0.7	1.3	-0.9	0.8	-0.7	0.7
Indifference point function ln k	0.1	0.2	1.0	-1.0	-0.2	-0.2	-0.2	0.2	1.0	-0.2	-0.1	0.1	0.5
Indifference point function log k	0.1	0.2	1.0	-1.0	-0.2	-0.2	-0.2	0.2	1.0	-0.2	-0.1	0.1	0.5
Patch foraging total patch changes 0 sec	1.1	2.1	3.8	-0.8	-1.7	-1.6	-1.2	1.5	2.0	-1.6	1.6	-1.1	1.2
Patch foraging total patch changes 12 sec	0.4	0.6	1.0	0.2	-0.8	-1.0	-0.8	0.8	-0.1	-1.0	0.8	-1.0	0.1
Patch foraging total patch changes 18 sec	1.5	2.4	3.6	-0.3	-1.8	-1.8	-1.4	1.7	1.5	-1.5	1.9	-1.8	0.8
Patch foraging total patch changes 24 sec	0.4	0.7	1.7	0.3	-1.1	-1.0	-0.8	0.8	0.2	-0.9	1.3	-1.2	0.2
Patch foraging total patch changes 6 sec	0.1	0.2	0.9	-0.1	-0.4	-0.4	-0.1	0.2	0.9	-0.4	0.1	0.3	0.5
Patch foraging time to switch 0 sec	2.5	5.0	6.9	1.5	2.5	2.4	2.1	-2.5	-2.6	2.3	-2.5	2.1	-1.6
Patch foraging water rate 0 sec	1.8	3.7	5.0	-1.4	-2.1	-2.0	-2.0	2.1	1.8	-2.1	2.2	-1.9	1.3
Patch foraging water rate 12 sec	1.1	2.2	5.5	-1.4	-1.5	-1.5	-1.2	1.4	2.3	-1.2	1.4	-1.2	1.3
Patch foraging water rate 18 sec	0.9	1.5	3.4	-0.6	-1.2	-1.3	-0.8	1.1	1.9	-1.3	1.5	-0.9	1.0
Patch foraging water rate 24 sec	1.0	1.4	3.4	-1.8	-0.9	-1.0	-1.0	0.9	1.9	-1.2	0.9	-0.7	1.1
Patch foraging water rate 6 sec	0.5	0.8	1.8	-1.3	-0.9	-0.9	-0.8	0.8	1.3	-0.5	0.7	-0.7	0.7
Seeking ratio, delayed vs. immediate footshock	0.3	0.3	2.2	0.3	0.4	0.5	0.1	-0.3	-1.5	0.1	-0.5	0.1	-0.4
Distance traveled before self-admin	0.2	0.3	0.5	0.6	0.6	0.6	0.6	-0.5	-0.2	0.4	-0.5	0.7	-0.3
Distance traveled after self-admin	2.0	2.5	3.6	0.6	1.8	1.8	1.5	-1.9	-1.5	1.8	-1.7	1.8	-1.0
Extensor digitorum longus weight	0.1	0.5	1.7	1.2	-0.5	-0.6	0.2	0.7	1.3	-0.8	0.6	0.0	0.6
Bone: elastic displacement	0.2	0.2	0.7	-0.1	0.6	0.5	0.5	-0.5	-0.3	0.5	-0.5	0.8	-0.1
Bone: elastic work	0.3	0.4	1.0	-0.7	0.6	0.5	0.3	-0.6	-0.2	0.7	-0.9	1.0	-0.0
Bone: endosteal estimation	1.1	2.4	3.7	-0.2	-1.7	-1.7	-1.4	1.8	1.3	-1.8	1.8	-1.9	0.8
Bone: endosteal perimeter	2.3	4.8	6.3	-1.0	-2.3	-2.4	-2.1	2.5	2.3	-2.5	2.4	-2.5	1.4
Epididymis fat weight	0.7	2.2	6.8	2.6	1.6	1.3	1.7	-1.0	-1.6	0.8	-1.1	1.4	-1.0
Delta time in closed arm before/after self-admin	1.0	0.9	5.5	0.1	-1.0	-0.6	-0.1	0.6	2.3	-0.6	0.9	-0.1	0.8
Delta time in open arm before/after self-admin	1.6	1.6	2.5	-0.4	-1.2	-1.5	-1.4	1.6	0.6	-1.6	1.3	-1.6	0.6
Diff in mean of infusions in LGA sessions	3.8	4.6	6.9	1.3	2.5	2.3	2.4	-2.4	-1.1	2.2	-2.5	2.6	-1.3
Delay discount exponential model param	0.7	0.8	1.4	1.2	1.0	0.9	0.9	-0.7	-1.1	0.8	-0.9	0.7	-0.6
Extinction: sum of active levers before priming	0.3	0.4	1.4	0.2	-0.5	-0.6	-0.2	0.6	1.2	-0.7	0.7	-0.3	0.4
Active lever presses in extinction session 6	0.2	0.2	0.5	-0.7	0.6	0.6	0.1	-0.6	-0.5	0.4	0.3	0.4	-0.2
Bone: final force	0.1	0.2	0.4	-0.5	-0.5	-0.6	-0.6	0.6	-0.1	-0.5	0.0	-0.1	0.4
Bone: final moment	0.1	0.2	0.4	-0.4	-0.5	-0.6	-0.6	0.6	-0.1	-0.5	0.0	-0.2	0.4
Food consumed during 24 hour testing period	0.9	1.2	3.8	-1.9	-0.7	-0.7	-1.3	0.9	1.0	-0.9	0.7	-1.5	0.5
Glucose	0.4	0.6	1.3	-0.4	-0.6	-0.9	-0.8	1.1	0.5	-1.2	0.6	-0.8	0.6
Heart weight	0.4	0.5	2.1	-0.2	-0.8	-0.5	-0.3	0.7	1.4	-0.7	0.8	-0.2	0.8
Delay discount hyperbolic model param	0.9	1.0	1.2	1.1	1.1	1.1	1.1	-1.0	-1.0	1.0	-1.1	0.9	-0.7
Intermittent access intake day 1-15 change	0.4	0.8	2.3	-1.5	-0.8	-0.7	-1.0	0.8	0.9	-0.9	0.6	-0.7	0.8
Intermittent access intake escalation	0.6	1.2	3.1	-1.8	-0.9	-1.0	-1.3	1.0	0.9	-1.1	0.9	-0.9	0.8
Intermittent access intake escalation 2	0.4	0.4	1.0	-0.9	-0.4	-0.6	-1.0	0.7	-0.3	-0.7	0.5	-0.9	0.2
Intermitt. access day 1 inactive lever presses	0.4	1.7	4.4	0.3	1.5	1.3	0.9	-1.4	-2.1	1.4	-1.3	1.0	-0.8
Intermitt. access day 15 inactive lever presses	1.1	2.2	3.2	0.8	1.7	1.6	1.5	-1.7	-1.3	1.6	-1.6	1.8	-0.7
Intermitt. access escalation Index	0.1	0.2	0.4	-0.6	0.5	0.5	0.1	-0.4	-0.3	0.6	-0.3	0.5	-0.1
Intermittent access day 1 total infusions	0.6	1.0	1.5	-1.2	-0.8	-1.1	-1.1	1.1	0.8	-1.2	0.9	-0.8	0.7
Intermittent access day 15 total infusions	1.6	2.4	5.3	-2.3	-1.2	-1.5	-1.9	1.6	0.8	-1.8	1.2	-1.4	1.0
Intermittent access terminal intake (last 3 days)	1.0	1.3	2.4	-1.5	-0.8	-1.2	-1.5	1.3	0.1	-1.4	0.9	-1.3	0.6
Intermittent access total infusions	1.0	1.2	2.1	-1.2	-0.8	-1.2	-1.5	1.3	-0.0	-1.5	0.9	-1.3	0.4
Intermittent access day 1 locomotion	0.2	0.3	1.5	-1.2	0.1	-0.4	-0.7	0.5	-0.2	-0.4	-0.2	-0.3	0.2
Intermittent access day 15 total locomotion	0.2	0.4	1.4	-1.2	-0.1	-0.6	-0.8	0.6	-0.2	-0.5	0.2	-0.5	0.4
Intermittent access total locomotion	0.2	0.3	0.6	-0.8	0.1	-0.5	-0.7	0.7	-0.4	-0.7	-0.1	-0.5	0.2
Intermittent access standard deviation	0.1	0.1	0.6	0.8	-0.0	-0.3	0.0	0.4	-0.0	-0.6	0.4	-0.3	-0.1
Left kidney weight	0.2	0.9	6.9	2.6	0.5	0.6	1.2	-0.2	0.1	0.2	0.1	0.2	-0.6
Right kidney weight	0.2	0.9	7.3	2.7	0.3	0.4	1.0	-0.1	-0.1	0.1	0.2	0.0	-0.6
Cocaine induced anxiety	1.4	2.0	4.2	1.2	1.5	1.5	1.5	-1.5	-0.9	1.5	-2.1	1.6	-0.7
Post-drug Anxiety	0.7	0.7	1.4	0.6	0.7	0.9	1.0	-0.9	0.7	0.7	-1.2	1.2	0.0
Baseline Anxiety	1.5	1.7	4.1	-0.9	-1.4	-1.2	-1.0	1.2	2.0	-1.2	1.5	-1.0	1.1
Tail length	0.3	1.1	6.6	2.6	-0.4	-0.5	0.6	0.6	1.2	-0.6	0.8	-0.5	0.1
Length with tail	0.4	1.6	12.1	3.5	0.6	0.4	1.5	-0.2	0.2	0.0	-0.2	0.8	-0.4
Length without tail	0.9	2.9	4.8	2.2	1.9	1.7	2.0	-1.6	-1.1	1.3	-1.7	2.1	-1.0
Times rat made contact with spout	0.6	0.7	1.3	1.0	1.1	0.9	1.0	-0.8	-0.5	0.8	-0.8	0.6	-0.7
Lifetime Intake	1.3	1.6	2.8	-1.5	-1.1	-1.4	-1.7	1.4	0.0	-1.5	1.0	-1.5	0.5
Liver weight, left	0.3	0.6	2.6	1.6	0.6	0.3	0.4	-0.0	-1.5	-0.2	0.0	0.1	-0.6
Liver weight, right	1.5	2.7	10.7	3.3	1.6	1.3	1.6	-0.9	-2.0	0.9	-0.9	0.9	-1.4
Locomotor activity	0.2	0.4	1.0	0.6	0.2	0.8	0.8	-0.6	1.0	0.7	-0.2	0.4	-0.2
Locomotor testing distance	0.4	0.7	2.3	0.9	-1.1	-0.5	-0.1	0.6	1.5	-0.4	1.0	-0.8	0.3
Locomotor testing rearing	0.2	0.5	3.9	2.0	-0.2	0.1	0.7	-0.0	0.4	0.2	0.3	-0.0	-0.2
Locomotion in novel chamber	0.7	0.9	4.6	-2.1	-0.4	-0.8	-1.3	0.7	-0.1	-0.7	-0.0	-0.7	0.3
Locomotion in novel chamber post-restriction	1.8	2.9	8.2	-2.9	-1.5	-1.7	-2.0	1.7	1.7	-1.6	1.0	-1.3	1.2
Fecal boli incidents, locomotor time 1	1.9	2.7	5.2	-2.0	-1.9	-1.5	-2.1	1.2	-0.0	-1.2	2.3	-1.9	1.0
Change in fecal boli incidents, locomotor task	1.9	1.9	3.5	1.0	1.4	1.5	1.7	-1.4	0.1	1.4	-1.9	1.7	-0.5
Time >=10cm from walls, locomotor time 1	1.1	1.2	3.0	-1.7	-1.0	-1.0	-1.2	1.1	0.7	-0.7	1.2	-1.0	0.7
Bouts of movement, locomotor time 1	0.8	0.9	3.1	-0.8	-0.8	-0.8	-0.5	0.7	1.8	-0.8	0.9	-0.3	1.1
Total resting periods, locomotor time 1	0.6	0.6	2.6	-1.0	-0.5	-0.6	-0.4	0.4	1.6	-0.6	0.4	-0.0	1.0
Rest time, locomotor task time 1	0.4	0.5	1.8	-1.4	-0.5	-0.3	-0.5	0.3	1.2	-0.4	0.2	-0.1	0.8
Distance moved, locomotor task time 1	0.2	0.3	0.8	0.9	-0.5	-0.6	-0.3	0.5	-0.0	-0.5	0.8	-0.7	-0.1
Vertical activity count, locomotor time 1	0.1	0.3	1.1	0.6	-0.5	-0.7	-0.3	0.6	0.2	-0.5	1.0	-0.7	0.0
Time >=10cm from walls, locomotor time 2	1.0	1.4	2.1	-0.7	-1.3	-1.4	-1.3	1.5	0.5	-1.1	1.5	-1.5	0.7
Bouts of movement, locomotor time 2	0.1	0.1	0.3	0.1	-0.3	-0.5	-0.2	0.3	0.3	-0.5	0.2	-0.3	0.3
Total resting periods, locomotor time 2	0.0	0.1	0.2	0.0	-0.2	-0.4	-0.2	0.2	0.2	-0.3	0.3	-0.2	0.2
Rest time, locomotor task time 2	1.0	1.3	2.1	0.4	1.2	1.3	1.0	-1.2	-1.3	1.4	-1.0	1.1	-0.8
Distance moved, locomotor task time 2	1.8	2.2	4.0	-0.3	-1.6	-1.8	-1.6	1.9	0.5	-1.9	1.3	-2.0	0.6
Vertical activity count, locomotor time 2	0.9	1.3	2.2	0.1	-1.2	-1.4	-1.1	1.3	0.5	-1.4	1.3	-1.5	0.5
Light reinforcement 1	0.7	1.7	3.4	1.8	1.3	1.3	1.5	-1.2	-1.4	1.3	-0.9	1.3	-0.9
Light reinforcement 2	0.2	0.3	1.2	0.3	0.5	0.5	0.3	-0.6	-1.1	0.5	-0.4	0.5	-0.4
Bone: marrow area	0.9	2.0	3.0	-0.1	-1.6	-1.6	-1.3	1.7	1.2	-1.6	1.6	-1.7	0.8
Bone: maximum diameter	1.3	2.4	4.0	-0.3	-1.7	-1.8	-1.4	2.0	1.5	-2.0	1.5	-1.5	1.2
Bone: maximum force	0.3	0.5	1.0	-1.0	-0.7	-0.9	-0.9	0.7	0.2	-0.7	0.1	-0.2	0.6
Bone: maximum moment	0.3	0.5	0.9	-1.0	-0.7	-0.9	-0.9	0.8	0.3	-0.7	0.1	-0.3	0.6
Mean time between licks in bursts	0.8	1.8	4.2	0.1	-1.3	-1.5	-1.4	1.7	0.4	-1.6	1.7	-2.0	0.5
Mean num. licks in bursts	1.6	2.5	3.8	-1.6	-1.6	-1.6	-1.8	1.7	1.3	-1.6	1.5	-1.9	1.0
Cd content in liver	0.2	0.2	0.9	1.0	-0.1	-0.2	0.4	0.2	0.8	-0.1	0.0	0.2	-0.5
Co content in liver	1.1	1.3	2.1	-0.2	-1.3	-1.3	-1.1	1.2	0.7	-1.2	1.5	-1.4	1.1
Cu content in liver	0.3	0.4	1.9	1.4	-0.4	-0.4	0.3	0.3	0.9	-0.3	0.7	-0.4	-0.2
Fe content in liver	0.1	0.1	0.8	0.0	-0.1	-0.2	-0.3	0.2	-0.9	-0.2	0.2	-0.1	0.4
K content in liver	0.9	0.9	2.1	0.4	1.0	1.0	0.8	-1.0	-0.8	1.0	-1.0	0.4	-1.5
Mg content in liver	0.1	0.1	0.5	-0.1	0.2	0.2	0.1	-0.3	-0.0	0.3	-0.2	-0.1	-0.7
Mn content in liver	0.9	1.0	2.3	-0.5	1.1	1.0	0.5	-1.0	-1.5	1.1	-1.2	0.8	-1.0
Na content in liver	0.5	0.6	3.1	-0.2	0.5	0.4	0.0	-0.5	-1.8	0.5	-0.5	0.0	-1.2
Rb content in liver	0.1	0.1	0.9	0.4	0.1	0.1	0.4	-0.0	0.9	0.0	0.0	0.3	0.1
Se content in liver	4.1	4.9	10.5	0.9	2.1	2.1	1.7	-2.2	-2.7	2.3	-2.3	1.7	-3.2
Sr content in liver	0.5	0.4	0.7	-0.9	-0.7	-0.8	-0.8	0.7	0.2	-0.7	0.5	-0.6	0.5
Zn content in liver	1.4	1.6	2.6	0.4	-1.5	-1.4	-0.9	1.3	1.5	-1.3	1.6	-1.6	-0.0
Bone: minimum diameter	0.5	0.9	1.3	0.8	-1.1	-1.1	-0.7	1.1	0.7	-1.1	1.1	-1.1	0.4
Time in familiar zone, hab. session 1	0.0	0.0	0.1	-0.3	-0.1	-0.1	-0.2	0.2	-0.0	-0.2	-0.0	-0.3	0.1
Time in novel zone, hab. session 1	0.2	0.2	1.0	1.0	0.2	0.3	0.7	-0.4	0.3	0.3	-0.0	0.6	-0.1
Total zone transitions, hab. session 1	0.5	0.7	1.8	-0.2	0.7	0.9	0.8	-0.9	0.5	1.0	-1.2	1.3	-0.1
Total locomotion distance, hab. session 1	5.0	7.1	12.7	3.6	2.6	2.5	2.9	-2.6	-2.9	2.6	-2.2	2.3	-2.1
Locomotion velocity, hab. session 1	4.6	6.5	11.1	3.3	2.5	2.4	2.7	-2.5	-3.0	2.4	-2.1	2.2	-2.1
Time in familiar zone, hab. session 2	0.7	0.8	2.0	-0.5	-0.8	-0.9	-0.7	0.9	1.4	-1.0	0.7	-1.0	0.6
Time in novel zone, hab. session 2	0.1	0.1	0.6	0.0	-0.3	-0.2	-0.3	0.1	-0.8	-0.2	0.4	-0.1	0.0
Total zone transitions, hab. session 2	0.2	0.3	0.9	-0.3	0.0	0.2	0.4	-0.3	0.9	0.3	-0.4	0.9	0.4
Total locomotion distance, hab. session 2	2.6	3.4	8.7	2.9	1.6	1.6	2.1	-1.8	-1.7	1.7	-1.4	1.8	-1.3
Locomotion velocity, hab. session 2	2.8	3.7	9.8	3.1	1.7	1.7	2.3	-1.8	-1.5	1.8	-1.4	1.9	-1.3
Novel to familiar place preference ratio	0.1	0.1	0.3	0.5	0.4	0.3	0.4	-0.2	-0.4	0.2	-0.3	0.6	0.0
Novelty place preference	0.0	0.0	0.1	0.3	0.1	0.1	0.2	-0.0	-0.1	-0.0	-0.0	0.3	0.1
Time in novel zone, NPP test	0.0	0.0	0.1	0.0	-0.1	-0.2	-0.1	0.3	0.3	-0.3	0.2	0.1	0.4
Total zone transitions, NPP test	0.2	0.3	1.1	-1.0	-0.5	-0.3	-0.4	0.2	0.9	-0.2	0.1	0.1	0.6
Total locomotion distance, NPP test	1.9	2.6	6.9	2.5	1.2	1.3	1.4	-1.4	-2.6	1.4	-1.0	1.1	-1.4
Locomotion velocity, NPP test	2.7	3.8	9.4	2.8	1.6	1.6	1.8	-1.7	-3.1	1.7	-1.3	1.4	-1.7
Intraocular pressure	3.4	4.9	9.2	-3.0	-2.1	-2.2	-2.5	2.3	2.0	-2.2	1.9	-2.1	1.7
Delta distance traveled before/after self-admin	0.5	0.6	1.0	0.0	0.9	0.8	0.7	-0.9	-0.6	1.0	-0.8	0.9	-0.3
Delta ambulatory time before/after self-admin	0.3	0.4	0.7	-0.3	0.7	0.6	0.5	-0.8	-0.1	0.9	-0.5	0.8	-0.1
Parametrial fat weight	0.9	2.2	3.8	1.8	1.5	1.5	1.8	-1.4	-0.8	1.5	-1.3	1.9	-0.9
Pavlov. Cond. lever latency	1.3	1.6	3.0	1.0	1.3	1.4	1.5	-1.4	-0.7	1.3	-1.2	1.7	-0.6
Pavlov. Cond. magazine entry latency	1.4	1.8	2.7	-0.4	-1.6	-1.6	-1.3	1.6	1.3	-1.5	1.4	-1.4	0.9
Pavlov. Cond. change in total contacts	1.6	1.7	3.0	-0.7	-1.4	-1.5	-1.6	1.5	-0.2	-1.4	1.3	-1.7	0.5
Pavlov. Cond. index score	1.8	2.3	3.7	-0.6	-1.8	-1.7	-1.6	1.7	1.1	-1.6	1.6	-1.9	0.8
Pavlov. Cond. latency score	1.5	1.9	3.2	-0.6	-1.6	-1.6	-1.5	1.6	0.8	-1.6	1.4	-1.8	0.7
Pavlov. Cond. lever contacts	1.0	1.2	2.4	-0.6	-1.2	-1.2	-1.2	1.2	0.7	-1.1	1.0	-1.6	0.5
Pavlov. Cond. magazine entry number	1.7	2.2	3.2	0.4	1.8	1.8	1.4	-1.7	-1.3	1.6	-1.7	1.6	-0.9
Pavlov. Cond. intertrial magazine entries	0.9	1.1	1.5	0.8	1.1	1.2	1.0	-1.2	-1.1	1.2	-1.1	0.8	-0.9
Pavlov. Cond. lever-magazine prob. diff.	1.6	2.0	3.3	-0.7	-1.6	-1.6	-1.5	1.6	1.0	-1.5	1.4	-1.8	0.7
Pavlov. Cond. response bias	0.9	1.1	1.8	-0.4	-1.3	-1.2	-1.1	1.1	0.9	-1.0	1.2	-1.3	0.5
Pavlov. Cond. lever latency	13.6	18.5	24.5	3.1	4.9	4.7	4.1	-4.5	-4.9	4.5	-4.6	3.7	-3.3
Pavlov. Cond. magazine entry latency	6.0	7.3	9.7	-2.6	-3.1	-3.0	-2.7	2.7	3.0	-2.6	2.7	-2.1	2.2
Pavlov. Cond. change in total contacts	7.2	11.5	15.5	-2.2	-3.9	-3.8	-3.2	3.7	3.9	-3.6	3.6	-2.9	2.7
Pavlov. Cond. index score	11.7	15.8	21.0	-3.1	-4.6	-4.4	-3.9	4.2	4.4	-4.1	4.2	-3.4	3.1
Pavlov. Cond. latency score	10.8	14.3	19.1	-3.1	-4.4	-4.2	-3.7	3.9	4.2	-3.8	4.0	-3.2	2.9
Pavlov. Cond. lever contacts	12.7	17.5	25.5	-2.9	-4.8	-4.6	-3.9	4.4	5.1	-4.4	4.6	-3.5	3.3
Pavlov. Cond. magazine entry number	12.6	15.6	19.7	3.6	4.4	4.3	4.1	-4.1	-4.0	4.1	-4.1	3.6	-3.0
Pavlov. Cond. intertrial magazine entries	0.8	1.2	5.0	2.2	0.8	1.0	1.2	-0.8	-1.1	0.9	-0.6	0.4	-1.0
Pavlov. Cond. lever-magazine prob. diff.	11.3	15.1	20.2	-2.9	-4.5	-4.3	-3.8	4.1	4.2	-4.0	4.2	-3.4	3.0
Pavlov. Cond. response bias	15.0	20.4	26.9	-3.3	-5.2	-5.0	-4.4	4.8	4.9	-4.7	4.9	-4.0	3.4
Time in closed arm before self-admin	0.1	0.1	0.5	-0.7	0.1	0.2	-0.1	-0.1	0.0	0.2	-0.2	0.2	0.1
Time in closed arm after self-admin	0.3	0.3	2.2	-1.5	-0.1	0.3	-0.3	-0.1	0.6	0.3	-0.2	0.2	0.3
Time in open arm before self-admin	0.9	0.9	1.5	1.2	0.8	1.0	1.0	-1.2	-1.1	1.0	-0.6	0.8	-0.6
Time in open arm after self-admin	0.2	0.2	1.4	1.2	0.1	-0.3	0.2	0.2	-0.5	-0.2	0.3	-0.2	-0.2
Bone: periosteal estimation	1.4	2.9	4.6	-0.2	-2.0	-2.0	-1.7	2.1	1.1	-2.1	1.8	-2.0	1.0
Bone: periosteal perimeter	1.2	2.0	5.1	-0.1	-1.4	-1.4	-0.9	1.6	2.3	-1.6	1.6	-1.3	1.1
Bone: post-yield work	0.1	0.1	0.3	-0.2	0.2	0.0	0.1	-0.2	-0.0	0.3	-0.6	0.5	-0.1
Progressive ratio test 1 active lever presses	0.1	0.1	0.9	-0.9	0.3	0.1	-0.2	-0.0	-0.2	-0.0	-0.4	0.2	-0.0
Progressive ratio test 1 breakpoint	0.1	0.1	1.1	-1.0	0.2	0.0	-0.3	0.1	-0.1	0.0	-0.4	0.1	0.1
Progressive ratio test 1 inactive lever presses	0.5	0.8	1.2	-0.1	1.1	1.0	0.7	-1.0	-1.0	1.1	-0.8	1.0	-0.4
Progressive ratio test 2 active lever presses	1.4	1.7	2.8	-0.9	-1.0	-1.4	-1.5	1.6	0.1	-1.7	1.5	-1.6	0.5
Progressive ratio test 2 breakpoint	1.6	1.8	3.0	-1.0	-1.0	-1.5	-1.6	1.6	0.1	-1.7	1.6	-1.6	0.5
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.3	-0.4	-0.1	-0.3	-0.4	0.4	-0.2	-0.5	0.3	-0.3	0.1
Incentive Sensitization - Responses	1.3	1.8	3.5	-0.4	-1.1	-1.5	-1.4	1.6	0.5	-1.8	1.9	-1.5	0.6
Incentive Sensitization - Breakpoint	1.2	1.6	3.2	-0.3	-1.0	-1.4	-1.3	1.5	0.3	-1.7	1.8	-1.5	0.5
Sum of active levers in priming session hrs 5-6	0.5	0.4	0.8	0.9	0.8	0.6	0.8	-0.6	-0.6	0.6	-0.2	0.7	-0.5
Progressive ratio	1.0	1.6	3.2	-1.8	-1.6	-1.1	-1.5	1.0	1.3	-1.0	1.2	-1.1	1.0
Food seeking constrained by brief footshock	0.5	0.7	1.9	0.7	-1.2	-0.6	-0.3	0.7	1.4	-0.7	0.8	-0.7	0.6
Seeking ratio, punishment vs. effort	0.8	1.1	5.9	2.4	0.8	0.6	1.1	-0.5	-1.3	0.4	-0.4	0.3	-0.8
Retroperitoneal fat weight	2.1	8.9	36.5	6.0	2.9	2.3	3.8	-2.0	-1.6	1.9	-1.9	2.8	-1.8
Reaction time number correct	0.5	0.9	1.7	-0.1	0.7	1.2	1.0	-1.3	0.0	1.3	-1.3	1.2	-0.4
Reaction time mean minus median	0.2	0.4	1.4	-0.0	-0.8	-0.6	-0.4	0.7	1.2	-0.6	0.6	-0.4	0.5
Reaction time mean minus median AUC	0.1	0.3	1.2	-0.4	-0.6	-0.5	-0.4	0.6	1.1	-0.5	0.4	-0.3	0.5
Reaction time num false alarms	0.4	0.6	1.3	1.1	0.8	0.6	1.0	-0.7	-0.4	0.8	-0.3	0.8	-0.5
Reaction time num false alarms AUC	0.1	0.1	0.2	0.4	0.4	0.3	0.4	-0.4	-0.3	0.4	-0.1	0.3	-0.3
Reaction time trials correct on left	0.5	0.9	1.7	-0.1	0.7	1.2	1.0	-1.3	0.0	1.3	-1.3	1.2	-0.4
Reaction time trials on left	0.5	0.9	1.6	-0.1	0.7	1.2	1.0	-1.3	0.0	1.3	-1.2	1.2	-0.4
Reaction time mean	0.2	0.3	0.9	1.0	0.4	0.4	0.6	-0.5	-0.8	0.3	-0.3	0.7	-0.3
Reaction time mean AUC	0.2	0.3	0.5	0.7	0.4	0.5	0.6	-0.5	-0.7	0.3	-0.4	0.7	-0.2
Median of all reaction times	0.4	0.6	1.8	1.0	0.6	0.6	0.7	-0.7	-1.3	0.5	-0.5	0.8	-0.5
Reaction time omissions	0.3	0.4	0.8	0.7	-0.7	-0.6	-0.3	0.7	0.4	-0.8	0.9	-0.2	0.5
Reaction time false alarm rate	0.1	0.1	0.3	0.4	0.1	-0.2	-0.1	0.2	-0.5	-0.2	0.4	-0.2	-0.1
Reaction time premature initiation rate	0.4	0.5	3.9	2.0	-0.3	-0.4	0.2	0.6	-0.0	-0.7	0.5	-0.4	-0.0
Reaction time premature initiations	0.2	0.3	2.6	1.6	-0.0	0.1	0.5	0.0	0.0	-0.1	-0.0	0.1	-0.2
Std. dev. reaction times	0.2	0.3	0.5	0.7	-0.7	-0.5	-0.1	0.5	0.7	-0.6	0.6	-0.3	0.4
Reaction time trials completed	0.5	0.9	1.6	-0.1	0.7	1.2	1.0	-1.3	0.0	1.3	-1.2	1.2	-0.4
Reaction time trials AUC	0.4	0.8	1.5	0.1	0.6	1.1	1.0	-1.2	0.1	1.2	-1.1	1.1	-0.4
Run reversals in cocaine runway, females	0.4	0.4	1.8	1.3	-0.3	-0.2	0.3	0.5	1.0	-0.5	0.8	-0.2	0.2
Run reversals in cocaine runway, males	1.3	1.3	3.5	-1.6	-0.9	-1.0	-1.0	0.9	1.9	-1.0	0.9	-0.6	1.1
Latency to leave start box in cocaine runway	2.3	2.6	5.4	1.7	1.5	1.7	1.5	-1.7	-2.3	1.7	-1.4	1.1	-1.3
Latency to leave start box in cocaine runway, F	1.9	2.2	5.3	2.0	1.1	1.5	1.2	-1.4	-2.3	1.4	-1.1	0.7	-1.3
Latency to leave start box in cocaine runway, M	0.4	0.4	0.9	-0.1	0.7	0.7	0.5	-0.7	-0.9	0.7	-0.7	0.6	-0.5
Std. dev. time between licks in bursts	0.2	0.3	2.0	1.4	0.1	0.0	0.5	-0.1	-0.1	0.1	0.4	-0.3	-0.5
Total sessions with >9 infusions	1.1	1.4	2.6	-1.4	-1.2	-1.1	-1.6	1.1	-0.1	-1.3	1.1	-1.5	0.4
Short access day 1 total inactive lever presses	0.4	0.6	0.8	-0.9	-0.9	-0.6	-0.8	0.6	0.8	-0.7	0.8	-0.6	0.7
Short access day 10 total inactive lever presses	1.3	3.2	5.1	1.4	2.0	2.0	2.1	-2.1	-0.8	2.0	-1.7	2.3	-0.9
Short access day 1 total infusions	1.5	2.0	3.3	-0.9	-1.5	-1.6	-1.7	1.6	0.2	-1.7	1.6	-1.8	0.6
Short access day 10 total infusions	1.7	2.2	3.4	-1.4	-1.6	-1.5	-1.8	1.6	0.5	-1.6	1.5	-1.8	0.7
Short access total infusions	1.7	2.1	3.5	-1.6	-1.5	-1.5	-1.9	1.5	0.4	-1.6	1.5	-1.7	0.6
Short access day 1 locomotion	1.9	2.3	4.8	-2.2	-1.4	-1.5	-1.8	1.5	1.0	-1.5	1.1	-1.4	1.2
Short access day 10 total locomotion	0.6	1.1	1.8	-1.0	-0.7	-1.1	-1.2	1.4	0.6	-1.3	0.8	-1.2	0.9
Short access total locomotion	0.2	0.2	1.0	-1.0	-0.0	-0.2	-0.7	0.4	-0.5	-0.4	-0.2	-0.5	0.2
One hour access (0.3 mA shock)	0.9	1.0	2.0	-0.7	-1.0	-1.1	-1.1	1.1	0.8	-1.4	1.0	-1.1	0.5
Compulsive drug intake	0.8	0.9	1.5	0.3	1.1	1.2	1.0	-1.2	-1.0	1.0	-0.7	1.1	-0.6
One hour access (shock baseline)	1.5	2.3	3.5	-1.6	-1.6	-1.6	-1.9	1.7	1.0	-1.7	1.1	-1.7	0.9
Social response proportion	3.1	3.5	5.0	1.8	1.9	1.9	1.9	-1.8	-2.0	1.8	-2.2	1.8	-1.3
Social responses	1.3	1.7	4.8	2.2	1.1	1.2	1.6	-1.2	-0.5	1.0	-1.4	1.4	-0.7
Social time	2.2	3.0	3.7	1.5	1.7	1.8	1.8	-1.9	-1.8	1.9	-1.8	1.9	-1.1
Soleus weight	0.2	0.7	4.3	2.1	0.4	0.3	1.1	-0.3	0.2	0.3	-0.3	0.6	-0.4
Bone: stiffness	0.1	0.2	0.8	0.1	0.4	0.2	0.3	-0.3	-0.5	0.2	-0.7	0.9	0.0
Tibialis anterior weight	0.1	0.3	1.6	1.3	0.3	0.3	0.7	-0.2	0.3	0.2	-0.2	0.7	-0.0
Time to tail flick, vehicle, before self-admin	0.1	0.1	0.2	0.2	-0.3	-0.1	-0.1	0.3	0.4	-0.2	0.3	-0.2	0.3
Time to tail flick, vehicle, after self-admin	0.9	1.2	2.1	-1.0	-1.4	-1.0	-1.0	1.0	1.4	-0.7	1.4	-1.0	0.8
Time to tail flick, test, before self-admin	1.1	1.2	2.0	-0.6	-1.3	-1.2	-1.0	1.2	1.4	-1.2	0.8	-1.1	0.7
Time to tail flick, test, after self-admin	0.7	0.8	1.7	-0.0	-1.2	-0.9	-0.6	0.8	1.1	-0.6	1.3	-0.9	0.7
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	1.6	-1.3	-0.9	-0.8	-0.9	0.7	0.8	-0.6	0.9	-0.8	0.5
Delta time to tail flick, test, before/after SA	0.9	0.9	1.6	0.8	0.9	1.1	1.1	-1.1	-0.9	1.3	-0.6	1.1	-0.6
Tibia length	0.5	1.3	2.2	-1.4	-1.3	-1.1	-1.5	1.2	0.3	-1.3	1.0	-1.2	0.8
Ambulatory time before self-admin	0.1	0.2	0.4	-0.1	0.5	0.5	0.3	-0.4	-0.1	0.3	-0.5	0.6	-0.1
Ambulatory time after self-admin	1.2	1.4	2.5	-0.1	1.5	1.3	1.1	-1.4	-0.9	1.4	-1.3	1.6	-0.5
Bone: tissue strength	2.5	2.5	5.2	0.1	1.9	1.5	1.3	-1.5	-1.6	1.6	-2.3	2.1	-0.7
Total heroin consumption	0.1	0.1	0.2	0.4	0.3	0.2	0.4	-0.3	-0.1	0.2	0.3	0.3	-0.4
Bone: trabecular number	0.2	0.4	0.8	-0.2	0.7	0.5	0.5	-0.7	-0.5	0.7	-0.9	0.8	-0.3
Bone: trabecular spacing	0.3	0.4	0.9	-0.5	-0.8	-0.6	-0.8	0.6	0.1	-0.5	0.8	-0.9	0.3
Bone: trabecular thickness	0.2	0.3	1.7	0.7	0.1	0.0	0.6	-0.0	1.3	0.0	-0.0	0.7	0.3
Bone: trabecular tissue density	2.4	3.5	5.7	2.2	1.9	2.0	2.4	-1.8	-0.4	1.9	-1.8	2.3	-1.0
Water consumed over 24 hours	0.7	0.9	1.4	0.5	1.2	1.1	1.1	-1.0	-0.3	1.0	-1.1	1.0	-0.6
Number of responses in last shaping day	1.1	1.2	4.3	2.1	0.9	0.6	0.9	-0.6	-1.9	0.4	-0.4	0.2	-0.9