Hub : Genes

Thap11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Thap11 0.19 0.09 0.0e+00 0.26 0.23 0.25 0.26 2.6e-24 1.1e-21 1.4e-23 4.4e-24
2 IC gene expression Thap11 0.29 0.13 1.2e-11 0.24 0.19 0.18 0.22 2.3e-10 2.0e-08 3.1e-08 1.2e-09
3 NAcc gene expression Thap11 0.24 0.12 0.0e+00 0.23 0.22 0.22 0.22 1.0e-33 3.2e-32 4.0e-32 7.7e-33
4 PL gene expression Thap11 0.09 0.05 9.1e-13 0.11 0.11 0.11 0.11 7.2e-12 1.9e-12 6.5e-12 5.5e-12
5 OFC gene expression Thap11 0.25 0.13 2.5e-05 0.21 0.13 0.17 0.19 1.2e-05 6.0e-04 8.9e-05 2.6e-05
6 pVTA gene expression Thap11 0.19 0.1 3.3e-16 0.2 0.2 0.18 0.2 1.1e-15 5.1e-16 9.6e-15 4.5e-16
7 BLA gene expression Thap11 0.16 0.09 5.2e-10 0.15 0.18 0.17 0.17 3.9e-08 8.8e-10 3.4e-09 2.2e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.10.3-0.3-0.5-0.5-0.4-0.3-0.3-0.3
Area under the delay curve0.00.00.00.00.00.10.00.1-0.1-0.1
BMI with tail0.10.20.4-0.60.1-0.3-0.5-0.5-0.5-0.1
BMI without tail0.00.10.3-0.10.60.20.10.00.00.2
Body weight0.21.11.6-1.0-1.1-1.3-1.2-0.9-1.0-0.6
Weight adjusted by age0.00.00.0-0.1-0.0-0.10.00.0-0.0-0.2
Bone surface1.22.22.8-1.2-1.7-1.7-1.7-1.3-1.5-1.3
Bone volume1.01.82.3-1.1-1.4-1.5-1.5-1.1-1.3-1.3
Breakpoint value in progressive ratio session1.61.92.41.51.11.51.51.11.51.4
Number of licking bursts0.71.12.2-1.5-1.1-0.9-1.1-1.0-1.0-0.2
Context. condit. distance diff. score0.10.10.40.60.20.10.20.50.30.4
Locomotion velocity, session 10.00.10.2-0.1-0.10.0-0.3-0.3-0.4-0.1
Locomotion distance, session 10.20.20.50.40.50.70.40.40.30.6
Locomotion velocity, session 21.31.52.71.11.11.31.01.21.01.6
Locomotion distance, session 20.40.51.30.70.50.90.40.60.41.1
Locomotion velocity, session 30.20.20.40.30.50.40.50.40.50.6
Locomotion distance, session 30.10.10.20.10.1-0.00.20.30.40.2
Stereotopy head waving bouts, day 30.20.20.7-0.8-0.3-0.5-0.3-0.5-0.5-0.3
Stereotopy head waving duration, day 30.60.71.2-1.1-0.8-1.0-0.8-0.9-0.9-0.5
Locomotion velocity, session 70.10.10.20.50.20.00.10.20.1-0.4
Locomotion distance, session 70.00.00.10.20.20.00.20.30.3-0.1
Stereotopy head waving bouts, day 70.30.40.9-0.6-0.6-0.9-0.5-0.6-0.5-0.4
Stereotopy head waving duration, day 70.91.11.5-1.1-1.0-1.2-0.9-1.1-1.0-0.8
Locomotion velocity, session 80.10.10.30.5-0.00.1-0.10.1-0.00.5
Locomotion distance, session 80.60.91.61.30.80.90.71.00.71.3
Degree of sensitization distance0.00.00.2-0.2-0.1-0.0-0.1-0.1-0.2-0.4
Degree of sensitization stereotypy0.50.50.8-0.6-0.7-0.9-0.7-0.7-0.7-0.6
Conditioned locomotion1.72.02.5-1.3-1.5-1.5-1.6-1.3-1.5-1.0
Cocaine response after cond. corrected0.70.82.2-0.7-0.5-0.7-0.7-1.0-1.0-1.5
Cocaine response after cond. not corrected0.20.20.7-0.2-0.1-0.2-0.2-0.5-0.5-0.8
Cocaine response before conditioning1.21.42.41.01.01.11.21.11.31.6
Saline control response3.54.76.0-2.0-2.2-2.2-2.5-2.2-2.4-1.5
Bone: connectivity density0.00.00.20.1-0.00.10.10.10.20.4
Bone: cortical apparent density0.40.51.00.11.00.70.90.51.00.6
Bone: cortical area0.30.41.3-0.3-0.5-0.7-0.7-0.5-0.6-1.1
Bone: cortical porosity0.80.82.91.70.70.40.51.00.60.7
Bone: cortical porosity0.60.72.61.60.70.40.50.90.50.5
Bone: cortical thickness0.10.20.6-0.2-0.3-0.5-0.4-0.4-0.4-0.8
Bone: cortical thickness0.10.10.30.40.2-0.10.10.60.3-0.3
Bone: cortical tissue density0.40.61.00.11.00.71.00.51.00.6
Condit. Reinf. active minus inactive responses3.94.45.52.12.32.32.22.12.11.3
Condit. Reinf. active-inactive response ratio3.53.75.22.32.11.92.01.91.91.2
Condit. Reinf. active responses3.03.84.91.92.12.22.02.01.91.3
Condit. Reinf. inactive responses0.20.20.40.00.50.60.50.50.60.3
Incentive salience index mean2.32.83.81.81.81.91.71.71.61.1
Condit. Reinf. lever presses0.20.30.80.90.60.80.40.60.40.3
Condit. Reinf. active minus inactive responses0.70.91.3-1.0-0.6-1.1-1.0-0.9-0.9-1.1
Condit. Reinf. active-inactive response ratio0.80.91.6-1.3-0.7-1.0-0.9-0.9-0.8-1.1
Condit. Reinf. active responses0.20.30.6-0.4-0.2-0.7-0.7-0.5-0.6-0.6
Condit. Reinf. inactive responses0.40.51.21.10.80.60.50.70.60.7
Condit. Reinf. lever presses3.14.36.02.11.91.71.82.12.22.4
Condit. Reinf. lever reinforcers received0.00.00.10.00.3-0.2-0.2-0.0-0.0-0.0
Conditioned reinforcement - actives0.91.52.41.51.51.31.21.11.00.8
Conditioned reinforcement - inactives0.30.41.1-0.5-0.3-0.5-0.5-1.1-0.5-0.7
Conditioned locomotion0.81.11.3-0.9-0.8-1.1-1.1-1.2-1.1-1.1
Patch foraging indifference point 0 sec2.64.95.5-2.2-2.3-2.3-2.4-2.2-2.2-1.9
Patch foraging indifference point AUC1.62.33.5-1.9-1.5-1.9-1.7-1.3-1.4-0.7
Delay disc. indifference point, 0s delay0.60.60.90.80.81.00.80.60.70.9
Delay disc. indifference point, 16s delay0.10.10.2-0.2-0.1-0.0-0.20.2-0.3-0.4
Delay disc. indifference point, 2s delay0.30.30.4-0.6-0.7-0.5-0.6-0.4-0.6-0.4
Delay disc. indifference point, 24s delay0.00.00.2-0.2-0.1-0.1-0.00.4-0.00.1
Delay disc. indifference point, 4s delay0.10.10.20.30.30.40.40.00.50.2
Delay disc. indifference point, 8s delay0.00.00.1-0.00.0-0.00.1-0.2-0.1-0.4
Indifference point function ln k0.20.40.80.90.60.80.70.40.4-0.3
Indifference point function log k0.20.40.80.90.60.80.70.40.4-0.3
Patch foraging total patch changes 0 sec2.54.85.4-2.1-2.3-2.3-2.3-2.2-2.2-1.9
Patch foraging total patch changes 12 sec2.73.54.7-2.2-2.1-2.1-2.0-1.7-1.7-1.0
Patch foraging total patch changes 18 sec2.23.35.0-1.8-2.0-2.2-2.0-1.5-1.6-1.7
Patch foraging total patch changes 24 sec0.30.61.2-1.0-1.1-0.9-0.7-0.5-0.20.3
Patch foraging total patch changes 6 sec2.03.03.6-1.8-1.9-1.9-1.9-1.8-1.6-0.9
Patch foraging time to switch 0 sec0.81.62.41.51.01.31.21.11.31.5
Patch foraging water rate 0 sec1.42.93.9-2.0-1.8-1.7-1.6-1.5-1.6-1.6
Patch foraging water rate 12 sec0.20.41.0-0.7-1.0-0.6-0.5-0.5-0.3-0.5
Patch foraging water rate 18 sec0.20.30.7-0.7-0.9-0.6-0.3-0.30.0-0.3
Patch foraging water rate 24 sec0.10.10.3-0.2-0.4-0.20.00.10.1-0.6
Patch foraging water rate 6 sec1.01.52.4-1.4-1.3-1.3-1.0-1.0-0.8-1.5
Seeking ratio, delayed vs. immediate footshock2.73.23.9-1.7-1.7-1.7-1.8-1.8-2.0-1.9
Distance traveled before self-admin1.11.42.2-1.5-1.2-1.4-1.2-1.0-0.7-1.3
Distance traveled after self-admin0.20.30.7-0.7-0.5-0.5-0.4-0.8-0.3-0.4
Extensor digitorum longus weight0.83.35.01.81.51.41.82.22.21.7
Bone: elastic displacement2.12.43.5-1.7-1.4-1.5-1.4-1.6-1.5-1.9
Bone: elastic work0.91.12.2-1.2-0.8-1.0-0.8-1.0-0.9-1.5
Bone: endosteal estimation0.10.10.4-0.3-0.2-0.4-0.2-0.3-0.2-0.6
Bone: endosteal perimeter0.10.20.6-0.2-0.3-0.4-0.5-0.2-0.4-0.8
Epididymis fat weight1.96.68.4-2.2-2.8-2.9-2.7-2.2-2.4-2.7
Delta time in closed arm before/after self-admin0.10.10.2-0.2-0.4-0.2-0.3-0.2-0.4-0.2
Delta time in open arm before/after self-admin0.10.10.3-0.2-0.1-0.1-0.0-0.5-0.0-0.3
Diff in mean of infusions in LGA sessions0.50.61.30.80.40.70.71.00.71.1
Delay discount exponential model param0.00.00.0-0.1-0.1-0.2-0.1-0.2-0.0-0.1
Extinction: sum of active levers before priming0.80.91.11.11.11.01.00.41.00.8
Active lever presses in extinction session 60.00.00.10.20.20.00.00.2-0.1-0.2
Bone: final force1.11.72.51.61.31.21.31.51.30.9
Bone: final moment0.40.71.11.10.80.80.80.90.90.5
Food consumed during 24 hour testing period0.10.10.2-0.1-0.4-0.4-0.4-0.1-0.2-0.0
Glucose1.21.82.91.11.41.71.60.91.41.2
Heart weight0.00.00.00.20.20.10.0-0.00.00.0
Delay discount hyperbolic model param0.00.00.1-0.1-0.2-0.3-0.2-0.2-0.1-0.2
Intermittent access intake day 1-15 change1.32.63.71.51.91.61.71.31.81.5
Intermittent access intake escalation1.42.83.81.61.91.71.81.41.81.6
Intermittent access intake escalation 21.11.21.81.11.31.21.20.81.10.9
Intermitt. access day 1 inactive lever presses0.00.10.30.30.40.40.20.10.00.6
Intermitt. access day 15 inactive lever presses0.00.00.10.20.20.20.20.30.20.0
Intermitt. access escalation Index0.30.51.1-0.8-1.1-0.5-0.6-0.7-0.6-0.5
Intermittent access day 1 total infusions0.10.10.40.60.50.40.20.2-0.20.1
Intermittent access day 15 total infusions1.92.94.61.92.21.91.71.21.41.3
Intermittent access terminal intake (last 3 days)3.24.26.02.32.42.22.11.71.81.6
Intermittent access total infusions2.73.24.72.22.11.91.81.61.51.3
Intermittent access day 1 locomotion1.31.62.5-1.1-1.0-1.1-1.2-1.4-1.6-1.3
Intermittent access day 15 total locomotion0.30.61.4-0.7-0.2-0.6-0.6-1.2-0.8-0.9
Intermittent access total locomotion0.20.20.6-0.10.2-0.2-0.3-0.5-0.6-0.8
Intermittent access standard deviation0.20.40.7-0.4-0.4-0.6-0.5-0.9-0.6-0.7
Left kidney weight1.77.711.12.52.22.32.53.13.23.3
Right kidney weight1.88.211.12.72.42.42.63.23.33.3
Cocaine induced anxiety2.73.84.3-2.1-1.8-1.9-2.0-2.1-2.1-1.7
Post-drug Anxiety0.60.71.0-1.0-0.9-0.8-0.9-0.8-0.9-0.5
Baseline Anxiety1.71.92.61.31.21.41.51.61.41.3
Tail length0.00.10.30.6-0.10.00.10.50.20.3
Length with tail0.10.51.7-0.0-1.3-1.0-0.7-0.2-0.3-0.2
Length without tail0.41.42.5-0.8-1.6-1.4-1.3-1.1-1.0-0.8
Times rat made contact with spout1.21.31.6-1.1-1.3-1.1-1.2-1.2-1.2-1.0
Lifetime Intake2.22.74.12.01.81.81.71.51.41.1
Liver weight, left0.30.51.1-0.6-1.0-0.8-0.7-0.6-0.5-0.0
Liver weight, right0.30.51.2-0.3-1.1-0.9-0.9-0.4-0.6-0.2
Locomotor activity2.64.04.6-1.9-1.9-2.1-2.1-1.8-2.0-2.1
Locomotor testing distance1.93.54.3-1.7-1.6-1.9-2.0-1.7-2.0-2.1
Locomotor testing rearing0.20.51.1-0.6-0.5-0.8-0.7-0.4-0.6-1.0
Locomotion in novel chamber2.33.03.7-1.7-1.5-1.6-1.8-1.7-1.8-1.9
Locomotion in novel chamber post-restriction1.52.53.1-1.7-1.4-1.5-1.5-1.4-1.7-1.7
Fecal boli incidents, locomotor time 10.70.91.8-1.1-1.0-1.1-0.9-1.4-0.7-0.4
Change in fecal boli incidents, locomotor task0.50.51.00.60.70.80.70.40.61.0
Time >=10cm from walls, locomotor time 10.30.30.7-0.5-0.5-0.6-0.5-0.8-0.6-0.2
Bouts of movement, locomotor time 10.10.10.1-0.3-0.2-0.2-0.2-0.4-0.30.1
Total resting periods, locomotor time 10.00.00.1-0.10.10.10.1-0.3-0.00.3
Rest time, locomotor task time 10.20.20.40.40.50.60.3-0.10.10.7
Distance moved, locomotor task time 10.10.20.6-0.6-0.5-0.4-0.4-0.2-0.2-0.7
Vertical activity count, locomotor time 10.51.12.2-1.3-1.1-1.1-0.9-0.4-0.7-1.5
Time >=10cm from walls, locomotor time 20.30.40.50.70.70.70.70.30.60.6
Bouts of movement, locomotor time 20.61.01.90.91.00.91.01.40.90.9
Total resting periods, locomotor time 20.71.32.01.01.11.01.11.41.11.1
Rest time, locomotor task time 20.60.81.30.81.00.91.00.50.91.1
Distance moved, locomotor task time 21.01.22.5-1.0-1.0-1.0-1.0-1.0-1.0-1.6
Vertical activity count, locomotor time 21.21.72.6-1.5-1.3-1.3-1.2-0.8-1.2-1.6
Light reinforcement 12.15.26.2-2.0-2.4-2.5-2.4-1.9-2.3-2.3
Light reinforcement 22.64.05.0-2.2-1.9-2.1-2.0-1.9-1.9-2.0
Bone: marrow area0.00.10.4-0.3-0.1-0.4-0.2-0.2-0.2-0.6
Bone: maximum diameter0.30.61.4-0.6-0.4-0.6-0.8-0.7-0.8-1.2
Bone: maximum force0.20.40.80.90.60.50.70.80.70.3
Bone: maximum moment0.00.00.20.40.10.00.20.20.3-0.2
Mean time between licks in bursts0.00.10.3-0.5-0.1-0.3-0.1-0.1-0.0-0.5
Mean num. licks in bursts0.10.10.40.60.20.10.20.10.1-0.5
Cd content in liver0.00.10.10.30.30.10.20.30.3-0.0
Co content in liver0.10.10.10.30.30.20.30.20.3-0.4
Cu content in liver1.01.21.71.30.71.11.11.31.11.1
Fe content in liver2.12.52.9-1.7-1.7-1.4-1.5-1.7-1.6-1.5
K content in liver0.20.20.40.20.60.50.40.10.30.4
Mg content in liver0.40.40.9-1.0-0.6-0.5-0.6-0.7-0.7-0.4
Mn content in liver0.91.02.1-1.5-0.9-0.9-0.9-1.0-0.9-0.8
Na content in liver0.10.10.7-0.5-0.00.30.1-0.8-0.2-0.1
Rb content in liver0.40.51.11.10.30.50.51.00.50.6
Se content in liver0.10.10.40.10.10.10.30.40.4-0.6
Sr content in liver1.00.81.4-0.7-1.2-1.0-1.0-0.7-0.9-0.7
Zn content in liver2.02.23.01.61.71.61.61.41.50.9
Bone: minimum diameter0.20.31.1-0.6-0.2-0.4-0.4-0.4-0.5-1.1
Time in familiar zone, hab. session 10.60.50.9-0.9-0.6-0.8-0.6-0.7-0.4-0.9
Time in novel zone, hab. session 10.30.30.60.80.60.70.50.60.30.4
Total zone transitions, hab. session 10.60.81.2-0.6-1.0-0.9-1.1-1.0-1.1-0.4
Total locomotion distance, hab. session 10.71.01.5-0.5-1.1-1.1-1.2-1.0-1.2-0.8
Locomotion velocity, hab. session 10.81.21.9-0.6-1.2-1.1-1.4-1.1-1.3-0.7
Time in familiar zone, hab. session 21.41.42.8-1.3-0.9-0.9-1.0-1.2-1.2-1.7
Time in novel zone, hab. session 24.64.65.02.02.12.12.22.12.22.2
Total zone transitions, hab. session 21.41.82.8-1.3-1.5-1.2-1.7-1.3-1.6-0.7
Total locomotion distance, hab. session 20.70.91.5-0.4-1.0-0.9-1.2-0.8-1.1-0.7
Locomotion velocity, hab. session 20.60.81.5-0.4-1.0-0.9-1.2-0.8-1.0-0.5
Novel to familiar place preference ratio1.41.52.01.01.31.21.41.11.31.4
Novelty place preference2.42.53.11.31.71.61.81.51.61.7
Time in novel zone, NPP test2.12.32.91.31.61.51.71.41.51.5
Total zone transitions, NPP test1.42.02.6-1.3-1.6-1.4-1.6-1.4-1.5-0.9
Total locomotion distance, NPP test0.50.71.2-0.6-1.1-0.9-1.1-0.8-0.9-0.5
Locomotion velocity, NPP test0.40.61.0-0.5-1.0-0.8-1.0-0.6-0.8-0.4
Intraocular pressure0.50.71.60.90.80.60.71.30.90.6
Delta distance traveled before/after self-admin0.40.40.90.70.60.80.70.20.51.0
Delta ambulatory time before/after self-admin0.81.01.61.11.11.21.00.40.81.2
Parametrial fat weight7.317.120.2-4.3-4.5-4.3-4.1-4.2-3.8-3.7
Pavlov. Cond. lever latency0.10.20.4-0.3-0.3-0.5-0.2-0.5-0.4-0.7
Pavlov. Cond. magazine entry latency0.91.11.70.81.11.31.01.31.00.9
Pavlov. Cond. change in total contacts0.91.01.50.70.91.00.91.01.01.2
Pavlov. Cond. index score0.70.91.40.80.81.10.71.20.91.2
Pavlov. Cond. latency score0.60.71.10.70.71.00.61.00.81.0
Pavlov. Cond. lever contacts0.80.91.50.90.81.10.81.10.91.2
Pavlov. Cond. magazine entry number0.91.11.6-0.9-1.1-1.2-1.0-1.3-1.1-1.0
Pavlov. Cond. intertrial magazine entries0.30.41.70.0-0.3-0.6-0.3-0.5-0.5-1.3
Pavlov. Cond. lever-magazine prob. diff.0.81.01.60.90.81.00.71.10.91.3
Pavlov. Cond. response bias0.50.60.90.70.70.90.71.00.70.9
Pavlov. Cond. lever latency1.62.12.6-1.4-1.5-1.2-1.4-1.5-1.6-1.6
Pavlov. Cond. magazine entry latency3.84.65.92.22.42.12.12.22.21.8
Pavlov. Cond. change in total contacts1.93.14.21.71.71.51.72.02.11.6
Pavlov. Cond. index score3.85.15.92.22.42.12.22.42.42.1
Pavlov. Cond. latency score3.95.15.92.22.42.12.22.32.32.2
Pavlov. Cond. lever contacts2.02.83.41.71.71.41.61.81.81.8
Pavlov. Cond. magazine entry number5.67.08.5-2.6-2.9-2.6-2.6-2.8-2.7-2.2
Pavlov. Cond. intertrial magazine entries4.06.06.6-2.3-2.2-2.5-2.5-2.5-2.5-2.6
Pavlov. Cond. lever-magazine prob. diff.4.25.66.92.32.62.22.32.52.52.1
Pavlov. Cond. response bias3.54.75.42.12.32.02.12.32.32.0
Time in closed arm before self-admin2.83.64.5-2.1-1.8-2.0-2.1-2.1-1.9-1.0
Time in closed arm after self-admin3.33.54.1-2.0-1.9-1.9-2.0-1.9-1.9-1.1
Time in open arm before self-admin2.12.33.51.61.31.31.51.91.71.1
Time in open arm after self-admin0.50.60.80.90.70.70.90.70.90.0
Bone: periosteal estimation0.20.51.3-0.6-0.5-0.8-0.6-0.5-0.5-1.2
Bone: periosteal perimeter0.50.91.7-0.7-0.9-1.0-1.0-0.7-0.9-1.3
Bone: post-yield work0.71.01.4-0.8-1.2-1.0-1.0-1.0-1.1-1.0
Progressive ratio test 1 active lever presses3.64.55.62.42.32.22.12.31.91.5
Progressive ratio test 1 breakpoint3.34.05.12.32.22.02.02.21.81.4
Progressive ratio test 1 inactive lever presses0.10.10.50.40.70.40.3-0.00.20.3
Progressive ratio test 2 active lever presses2.83.34.62.12.11.91.81.41.61.5
Progressive ratio test 2 breakpoint2.93.44.62.12.22.01.91.51.61.5
Progressive ratio test 2 inactive lever presses0.10.10.40.50.60.40.40.10.2-0.1
Incentive Sensitization - Responses0.91.31.91.31.41.21.10.70.91.1
Incentive Sensitization - Breakpoint1.21.52.21.41.51.31.20.81.01.2
Sum of active levers in priming session hrs 5-60.30.20.40.60.60.50.50.70.40.2
Progressive ratio0.10.10.70.0-0.2-0.3-0.30.80.20.1
Food seeking constrained by brief footshock1.72.03.41.41.11.31.31.21.71.8
Seeking ratio, punishment vs. effort0.50.81.20.80.81.01.00.10.91.1
Retroperitoneal fat weight6.929.530.7-5.4-5.3-5.5-5.4-5.4-5.3-5.5
Reaction time number correct1.22.33.01.41.71.61.61.61.41.3
Reaction time mean minus median0.61.62.81.71.31.01.01.61.10.9
Reaction time mean minus median AUC0.51.42.71.61.10.80.91.61.00.9
Reaction time num false alarms0.10.10.20.40.20.40.30.40.30.5
Reaction time num false alarms AUC0.00.00.00.1-0.10.0-0.00.1-0.10.2
Reaction time trials correct on left1.22.33.01.41.71.61.61.61.41.3
Reaction time trials on left1.32.43.21.41.81.71.61.71.41.3
Reaction time mean0.00.00.10.3-0.0-0.2-0.10.30.10.1
Reaction time mean AUC0.10.10.30.50.20.10.20.50.30.3
Median of all reaction times0.10.20.3-0.3-0.5-0.6-0.5-0.2-0.2-0.3
Reaction time omissions0.00.00.1-0.10.1-0.1-0.10.3-0.1-0.1
Reaction time false alarm rate0.40.50.8-0.6-0.9-0.8-0.8-0.7-0.8-0.5
Reaction time premature initiation rate1.11.62.11.21.11.21.31.21.51.2
Reaction time premature initiations2.34.14.81.92.02.12.12.02.21.9
Std. dev. reaction times0.20.30.70.80.70.20.30.80.50.3
Reaction time trials completed1.32.43.21.41.81.71.61.71.41.3
Reaction time trials AUC1.32.43.11.31.81.71.61.71.41.3
Run reversals in cocaine runway, females1.71.73.9-1.3-0.7-1.2-1.2-2.0-1.1-1.4
Run reversals in cocaine runway, males0.40.41.0-0.6-0.5-0.5-0.5-1.0-0.5-0.4
Latency to leave start box in cocaine runway0.10.10.20.00.20.40.4-0.00.30.3
Latency to leave start box in cocaine runway, F0.91.01.90.81.41.31.20.50.80.8
Latency to leave start box in cocaine runway, M1.41.32.8-1.2-1.7-1.3-1.2-0.7-0.9-0.8
Std. dev. time between licks in bursts1.72.32.6-1.2-1.6-1.5-1.6-1.4-1.5-1.6
Total sessions with >9 infusions1.82.23.11.81.71.71.61.31.30.6
Short access day 1 total inactive lever presses0.10.10.50.10.10.0-0.0-0.3-0.1-0.7
Short access day 10 total inactive lever presses0.10.20.4-0.6-0.3-0.5-0.6-0.5-0.5-0.3
Short access day 1 total infusions0.50.61.41.20.80.90.80.60.60.2
Short access day 10 total infusions0.50.61.31.10.80.90.70.80.50.3
Short access total infusions2.12.74.02.01.61.81.71.81.41.0
Short access day 1 locomotion0.30.40.60.80.80.70.70.30.60.4
Short access day 10 total locomotion1.73.25.3-1.7-1.5-1.6-1.7-1.6-2.0-2.3
Short access total locomotion0.40.51.4-0.4-0.6-0.5-0.6-0.7-0.8-1.2
One hour access (0.3 mA shock)1.71.92.81.61.71.41.31.41.11.2
Compulsive drug intake0.10.20.3-0.5-0.4-0.4-0.4-0.5-0.2-0.4
One hour access (shock baseline)1.31.93.11.81.71.51.31.21.01.2
Social response proportion0.80.92.01.40.91.10.90.90.70.5
Social responses0.10.10.40.60.20.40.20.20.1-0.2
Social time0.10.20.60.80.40.30.20.40.1-0.5
Soleus weight0.30.81.4-1.2-0.9-0.9-0.8-0.9-0.6-0.8
Bone: stiffness3.55.78.02.82.32.12.32.62.42.2
Tibialis anterior weight0.41.32.71.00.70.90.91.61.11.4
Time to tail flick, vehicle, before self-admin0.60.61.01.00.90.90.90.20.70.6
Time to tail flick, vehicle, after self-admin0.70.91.7-0.8-0.6-0.8-0.9-0.6-1.3-1.3
Time to tail flick, test, before self-admin2.52.64.0-1.5-2.0-1.8-1.8-1.3-1.6-1.1
Time to tail flick, test, after self-admin0.10.10.3-0.0-0.2-0.2-0.20.4-0.2-0.5
Delta time to tail flick, vehicle, before/after SA0.80.82.2-0.8-0.5-0.8-0.80.0-1.0-1.5
Delta time to tail flick, test, before/after SA1.21.21.61.01.21.11.21.31.10.6
Tibia length0.00.10.20.20.40.20.20.30.40.5
Ambulatory time before self-admin1.52.23.1-1.7-1.5-1.7-1.5-1.4-1.0-1.6
Ambulatory time after self-admin0.60.71.5-1.1-0.8-0.8-0.7-1.2-0.5-0.6
Bone: tissue strength0.10.10.2-0.30.10.30.4-0.30.10.0
Total heroin consumption1.01.11.51.20.91.21.10.91.01.0
Bone: trabecular number0.40.60.8-0.8-0.7-0.9-0.8-0.8-0.7-0.6
Bone: trabecular spacing0.00.00.1-0.2-0.3-0.2-0.1-0.2-0.1-0.3
Bone: trabecular thickness0.50.60.80.80.80.60.70.90.90.7
Bone: trabecular tissue density0.71.01.41.10.90.91.00.90.91.2
Water consumed over 24 hours0.20.20.4-0.1-0.6-0.6-0.6-0.5-0.40.0
Number of responses in last shaping day0.50.50.70.90.70.70.70.40.90.8