Tex2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Tex2 0.21 0.08 0.0e+00 0.23 0.25 0.24 0.23 2.7e-18 4.3e-20 1.8e-19 4.0e-18
2 Brain isoform ratio XM_006247647.4 0.05 0.02 3.0e-05 0.04 0.05 0.05 0.05 2.0e-04 3.3e-05 2.1e-05 2.1e-05
3 NAcc gene expression Tex2 0.44 0.11 0.0e+00 0.32 0.39 0.39 0.39 1.6e-49 2.5e-62 1.2e-63 1.1e-63
4 Brain isoform ratio NM_001100554.1 0.05 0.02 3.6e-05 0.04 0.05 0.05 0.05 1.0e-04 2.9e-05 2.7e-05 3.4e-05
5 Brain gene expression Tex2 0.23 0.07 0.0e+00 0.21 0.23 0.22 0.23 1.9e-19 6.2e-21 9.1e-21 4.6e-21
6 IL gene expression Tex2 0.21 0.1 3.1e-04 0.16 0.15 0.12 0.15 1.1e-04 1.7e-04 8.8e-04 1.5e-04
7 Liver intron excision ratio chr10_91998797_92017411 0.41 0.09 0.0e+00 0.42 0.43 0.44 0.45 3.1e-51 2.8e-51 3.7e-53 9.5e-55
8 BLA gene expression Tex2 0.35 0.1 0.0e+00 0.36 0.35 0.36 0.37 4.0e-20 3.3e-19 3.5e-20 2.3e-20
9 Liver alternative TSS XM_006247647.4 0.11 0.05 1.8e-08 0.07 0.05 0.05 0.06 2.1e-08 3.0e-06 6.9e-06 2.5e-07
10 Liver isoform ratio NM_001100554.1 0.11 0.05 5.7e-10 0.1 0.08 0.08 0.09 8.6e-11 1.6e-09 1.6e-09 1.4e-10
11 Liver intron excision ratio chr10_91998797_92045841 0.21 0.07 0.0e+00 0.18 0.17 0.17 0.17 2.4e-19 3.6e-18 3.6e-18 2.8e-18
12 LHb isoform ratio NM_001100554.1 0.31 0.14 2.6e-03 0.15 0.09 0.09 0.13 1.9e-04 4.3e-03 4.6e-03 5.7e-04
13 LHb isoform ratio XM_006247647.4 0.31 0.15 6.8e-03 0.14 0 0.04 0.09 3.1e-04 2.3e-01 3.7e-02 3.3e-03
14 LHb gene expression Tex2 0.3 0.13 1.4e-04 0.15 0.09 0.05 0.14 2.5e-04 3.5e-03 2.0e-02 3.5e-04
15 IC isoform ratio XM_006247647.4 0.07 0.04 6.2e-03 0.04 0.02 0.01 0.02 1.0e-02 3.3e-02 1.2e-01 4.5e-02
16 Liver alternative TSS XM_006247647.4 0.07 0.04 1.8e-06 0.05 0.04 0.04 0.05 1.6e-06 6.2e-05 1.2e-05 4.8e-06
17 pVTA isoform ratio XM_006247647.4 0.04 0.03 7.9e-03 0.03 0.01 0.02 0.02 1.1e-03 2.3e-02 7.1e-03 1.3e-02
18 PL gene expression Tex2 0.29 0.09 0.0e+00 0.34 0.34 0.35 0.35 9.3e-39 7.5e-39 1.3e-39 1.3e-39
19 IC gene expression Tex2 0.23 0.09 3.6e-11 0.2 0.22 0.23 0.19 9.4e-09 1.1e-09 6.8e-10 2.8e-08
20 OFC gene expression Tex2 0.52 0.14 3.7e-08 0.15 0.23 0.23 0.23 2.0e-04 2.8e-06 2.7e-06 4.2e-06
21 Liver gene expression Tex2 0.11 0.04 3.1e-10 0.11 0.08 0.08 0.09 5.3e-12 3.0e-09 2.4e-09 6.2e-10
22 Brain mRNA stability Tex2 0.07 0.05 3.4e-03 0.03 0.02 0.03 0.03 7.4e-04 5.8e-03 2.1e-03 2.0e-03
23 Adipose gene expression Tex2 0.25 0.07 2.5e-14 0.12 0.13 0.12 0.13 2.2e-13 2.7e-14 6.4e-13 4.1e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.30.51.50.81.01.2-1.00.80.4-0.50.20.40.40.4-0.80.80.40.40.30.50.70.30.91.1-0.90.8
Area under the delay curve0.30.32.50.40.50.8-0.70.50.3-0.0-0.2-0.0-0.0-0.0-0.80.80.30.1-0.10.30.3-0.10.20.8-0.61.6
BMI with tail1.24.117.42.91.50.7-1.31.72.3-1.81.71.51.51.5-4.24.22.41.81.51.71.40.51.2-0.52.9-0.3
BMI without tail2.68.027.54.12.61.7-2.32.53.1-2.52.52.32.32.3-5.25.23.33.02.13.02.21.21.90.13.30.4
Body weight2.912.822.84.84.13.5-3.83.83.9-3.53.53.23.23.2-4.74.74.14.03.13.93.52.63.22.12.30.8
Weight adjusted by age0.30.41.0-0.6-0.5-0.30.1-0.5-0.50.8-0.7-0.8-0.8-0.8-0.00.0-0.7-0.6-0.6-0.8-0.5-0.7-0.70.1-0.81.0
Bone surface3.05.513.72.53.13.7-3.02.62.1-2.22.12.22.22.2-0.60.61.92.11.92.02.52.32.53.4-1.71.7
Bone volume2.34.19.92.32.73.1-2.72.31.8-1.91.71.81.81.8-1.21.21.71.91.51.92.21.82.22.9-1.41.6
Breakpoint value in progressive ratio session0.20.31.50.40.1-0.0-0.10.10.3-0.70.40.90.90.90.1-0.10.1-0.11.0-0.00.20.50.10.10.1-1.2
Number of licking bursts0.10.11.8-0.20.10.4-0.30.10.20.00.0-0.0-0.0-0.00.3-0.3-0.2-0.10.1-0.00.00.0-0.10.7-1.40.5
Context. condit. distance diff. score0.00.00.10.1-0.1-0.30.10.00.1-0.20.30.10.10.1-0.30.3-0.10.10.40.0-0.1-0.4-0.1-0.10.3-0.1
Locomotion velocity, session 10.60.61.31.01.11.1-0.80.90.4-0.80.40.70.70.7-0.80.80.70.60.40.60.70.80.81.1-0.30.6
Locomotion distance, session 10.30.42.50.60.50.5-0.40.00.20.2-0.2-0.4-0.4-0.4-1.61.60.00.1-0.30.3-0.1-0.2-0.30.6-0.11.6
Locomotion velocity, session 20.50.61.30.80.70.6-0.50.60.3-0.90.91.21.21.20.1-0.10.60.40.80.60.51.10.40.90.0-0.9
Locomotion distance, session 20.10.20.60.40.30.5-0.20.1-0.0-0.00.10.10.10.1-0.80.8-0.0-0.20.1-0.5-0.2-0.1-0.40.7-0.60.7
Locomotion velocity, session 30.50.62.3-0.0-0.6-0.40.5-0.5-0.40.6-0.6-0.6-0.6-0.6-1.51.5-0.9-0.7-0.2-0.7-0.8-1.0-1.00.1-0.80.2
Locomotion distance, session 30.10.21.20.10.20.5-0.30.10.00.20.0-0.1-0.1-0.1-0.40.4-0.4-0.20.3-0.4-0.2-0.1-0.30.8-1.10.5
Stereotopy head waving bouts, day 30.50.61.7-0.6-0.9-0.70.8-0.6-1.00.7-1.1-0.8-0.8-0.8-0.40.4-0.7-0.8-1.3-0.6-0.6-1.0-0.5-0.5-0.20.2
Stereotopy head waving duration, day 30.30.41.1-0.5-0.8-0.40.6-0.3-0.80.5-0.9-0.7-0.7-0.7-0.50.5-0.6-0.7-1.1-0.4-0.4-0.9-0.60.0-0.60.7
Locomotion velocity, session 70.40.50.9-0.7-0.9-0.91.0-0.8-0.50.6-0.6-0.6-0.6-0.60.3-0.3-0.7-0.8-0.4-0.9-0.8-0.7-0.5-0.80.3-0.4
Locomotion distance, session 70.00.10.50.1-0.1-0.1-0.0-0.00.30.10.0-0.1-0.1-0.10.1-0.10.20.10.20.2-0.1-0.0-0.3-0.20.50.7
Stereotopy head waving bouts, day 70.60.72.0-0.8-0.8-0.50.8-0.7-1.40.7-1.1-0.6-0.6-0.6-0.10.1-1.1-0.9-1.0-1.0-1.0-0.9-0.90.0-1.1-0.2
Stereotopy head waving duration, day 71.41.74.2-1.6-1.4-1.01.3-1.2-2.11.1-1.5-0.9-0.9-0.90.7-0.7-1.6-1.6-1.4-1.7-1.4-1.2-1.3-0.1-1.7-0.6
Locomotion velocity, session 80.50.61.20.50.80.7-0.70.90.3-1.11.01.11.11.10.4-0.40.60.50.90.20.90.91.01.0-0.3-0.5
Locomotion distance, session 80.10.20.70.50.40.4-0.30.50.5-0.60.70.50.50.5-0.60.60.30.30.90.00.30.10.10.60.00.2
Degree of sensitization distance0.30.30.90.40.40.3-0.40.50.6-0.40.50.30.30.30.4-0.41.00.80.10.90.60.50.5-0.00.90.8
Degree of sensitization stereotypy0.90.92.1-0.8-1.0-0.91.1-1.1-1.50.9-1.0-0.7-0.7-0.7-0.30.3-1.3-1.1-0.8-1.2-1.4-1.0-1.4-0.4-0.8-0.7
Conditioned locomotion0.60.71.30.90.70.6-0.70.81.1-0.91.00.90.90.9-0.10.11.11.11.00.80.90.80.70.20.9-0.1
Cocaine response after cond. corrected0.70.82.3-1.0-0.40.10.3-0.4-0.70.8-1.0-0.8-0.8-0.81.3-1.3-0.7-0.9-0.7-1.1-0.5-0.6-0.40.7-1.51.5
Cocaine response after cond. not corrected1.11.24.9-1.4-0.60.10.6-0.7-1.00.9-1.2-0.9-0.9-0.91.8-1.8-1.2-1.4-0.6-1.4-0.8-0.6-0.60.9-2.20.9
Cocaine response before conditioning0.10.21.0-0.2-0.2-0.10.2-0.3-0.30.3-0.3-0.1-0.1-0.1-0.10.1-0.6-0.50.1-0.3-0.6-0.2-0.40.2-1.0-0.8
Saline control response2.43.16.82.01.30.6-1.21.51.9-2.02.12.12.12.1-1.21.22.02.12.01.91.61.71.3-0.22.6-2.0
Bone: connectivity density0.81.33.31.31.51.8-1.51.31.0-1.00.81.01.01.0-0.50.50.90.90.91.01.20.91.31.7-0.81.0
Bone: cortical apparent density3.85.29.1-1.8-2.5-2.52.4-2.4-1.92.6-2.6-2.9-2.9-2.9-1.51.5-2.4-2.3-2.2-2.2-2.5-3.0-2.5-1.9-0.30.7
Bone: cortical area1.01.612.11.71.01.2-0.90.80.8-0.50.40.30.30.3-3.53.50.40.40.40.30.4-0.20.21.0-0.61.1
Bone: cortical porosity3.74.07.02.22.32.2-1.92.01.6-2.52.02.62.62.60.1-0.11.81.62.31.42.02.62.11.9-0.1-1.6
Bone: cortical porosity2.83.14.92.22.12.2-1.92.01.4-2.01.62.12.12.1-1.21.21.61.51.91.31.71.91.71.9-0.5-0.7
Bone: cortical thickness7.412.220.8-1.9-3.4-3.33.4-3.4-3.13.7-3.9-4.0-4.0-4.0-4.14.1-3.5-3.6-3.7-3.7-3.9-4.6-4.0-2.7-0.70.7
Bone: cortical thickness4.65.48.1-1.4-2.4-2.62.5-2.6-2.32.5-2.4-2.5-2.5-2.5-2.12.1-2.5-2.3-2.4-2.4-2.8-2.8-2.9-2.40.0-0.3
Bone: cortical tissue density3.75.08.4-1.8-2.5-2.52.4-2.4-1.92.6-2.5-2.8-2.8-2.8-1.31.3-2.4-2.3-2.2-2.2-2.5-2.9-2.4-2.0-0.10.5
Condit. Reinf. active minus inactive responses2.52.84.32.11.91.6-1.91.71.7-2.11.82.02.02.0-0.80.81.82.01.91.71.81.81.51.00.7-0.6
Condit. Reinf. active-inactive response ratio1.11.12.01.11.21.0-1.21.11.0-1.41.21.31.31.30.2-0.21.11.31.21.11.21.21.10.60.3-0.5
Condit. Reinf. active responses3.54.36.22.52.32.1-2.32.32.3-2.42.32.42.42.4-1.11.12.32.42.22.02.32.11.91.50.7-0.3
Condit. Reinf. inactive responses1.31.52.61.51.51.6-1.51.51.6-1.21.21.11.11.1-1.21.21.31.21.10.91.40.91.11.4-0.20.9
Incentive salience index mean2.12.63.91.91.91.7-1.81.71.5-1.91.72.02.02.0-0.70.71.61.81.81.51.71.81.61.20.4-0.9
Condit. Reinf. lever presses0.40.62.00.70.90.8-0.60.70.4-0.80.71.01.01.0-0.30.30.60.70.70.50.71.00.70.50.3-1.4
Condit. Reinf. active minus inactive responses5.26.713.13.23.23.6-3.23.02.3-2.62.42.72.72.7-2.02.02.42.52.52.12.52.32.03.6-1.31.3
Condit. Reinf. active-inactive response ratio2.52.95.91.82.22.4-2.12.01.4-1.91.51.91.91.9-0.30.31.61.71.71.31.81.91.72.3-0.90.2
Condit. Reinf. active responses6.59.014.73.83.53.6-3.53.43.1-3.13.13.33.33.3-2.42.43.13.23.13.03.02.82.53.2-0.20.9
Condit. Reinf. inactive responses2.83.67.42.71.81.5-1.91.82.3-1.82.11.91.91.9-2.62.62.12.01.92.11.61.41.00.91.10.4
Condit. Reinf. lever presses2.02.75.22.31.81.6-1.61.61.5-1.81.81.91.91.9-1.91.91.61.61.81.61.41.51.11.00.6-0.6
Condit. Reinf. lever reinforcers received5.57.612.43.53.23.3-3.23.12.9-2.92.93.03.03.0-2.12.12.92.92.92.72.72.62.32.9-0.10.8
Conditioned reinforcement - actives0.61.02.01.31.10.9-1.11.01.4-1.11.00.90.90.9-1.31.31.00.91.11.10.90.60.70.50.50.1
Conditioned reinforcement - inactives0.71.02.01.41.10.6-0.90.81.4-1.11.20.90.90.9-1.11.11.01.11.21.20.80.70.90.11.0-0.3
Conditioned locomotion2.83.66.22.42.21.8-2.21.82.5-2.12.01.81.81.8-1.61.62.02.22.32.31.91.81.81.01.1-0.3
Patch foraging indifference point 0 sec3.46.411.63.42.92.7-2.82.73.0-2.42.62.22.22.2-3.03.02.82.82.62.62.41.91.92.00.91.3
Patch foraging indifference point AUC1.01.42.51.41.31.3-1.31.31.2-1.11.31.11.11.1-1.51.51.11.41.21.61.20.81.11.10.00.3
Delay disc. indifference point, 0s delay0.30.31.1-0.8-0.4-0.10.1-0.4-0.30.7-0.7-0.7-0.7-0.70.6-0.6-0.7-0.4-0.7-0.2-0.3-0.4-0.50.0-0.81.1
Delay disc. indifference point, 16s delay0.50.61.71.00.70.9-1.01.00.8-0.60.20.50.50.5-1.21.20.90.20.30.40.80.10.50.9-0.11.3
Delay disc. indifference point, 2s delay1.11.27.10.51.31.9-1.51.00.6-0.30.30.20.20.2-0.30.30.40.70.10.70.90.40.72.0-1.82.7
Delay disc. indifference point, 24s delay1.61.85.11.91.41.5-1.41.51.3-1.21.01.01.01.0-2.32.31.61.10.81.31.30.61.01.10.51.3
Delay disc. indifference point, 4s delay0.60.61.3-0.9-0.5-0.30.4-0.7-0.81.0-1.1-1.0-1.0-1.00.4-0.4-1.0-0.8-0.8-0.6-0.9-0.7-0.90.0-1.10.8
Delay disc. indifference point, 8s delay0.20.21.7-0.10.00.2-0.1-0.1-0.10.4-0.7-0.5-0.5-0.5-0.60.6-0.1-0.2-0.6-0.1-0.1-0.4-0.20.2-0.41.3
Indifference point function ln k0.40.71.5-0.4-0.9-0.60.9-0.6-0.80.8-1.1-0.9-0.9-0.9-0.80.8-0.7-1.1-0.8-1.2-1.0-1.1-1.1-0.2-0.40.5
Indifference point function log k0.40.71.5-0.4-0.9-0.60.9-0.6-0.80.8-1.1-0.9-0.9-0.9-0.80.8-0.7-1.1-0.8-1.2-1.0-1.1-1.1-0.2-0.40.5
Patch foraging total patch changes 0 sec3.56.611.93.53.02.8-2.92.83.1-2.52.72.32.32.3-2.92.92.92.92.72.62.52.02.02.10.81.3
Patch foraging total patch changes 12 sec5.97.712.13.13.43.0-3.53.02.9-2.83.22.82.82.8-1.51.53.03.52.63.53.02.92.62.40.70.8
Patch foraging total patch changes 18 sec2.74.16.92.62.21.8-2.12.12.2-2.12.22.12.12.1-2.02.02.32.52.12.51.91.91.61.31.10.1
Patch foraging total patch changes 24 sec2.95.09.53.02.62.5-2.62.42.3-2.02.01.91.91.9-3.13.12.22.32.22.42.01.51.72.00.01.4
Patch foraging total patch changes 6 sec2.43.66.72.62.22.0-2.12.02.1-1.82.01.71.71.7-2.32.31.92.12.12.01.81.41.51.40.70.6
Patch foraging time to switch 0 sec0.50.93.7-1.2-0.8-1.10.8-1.0-1.20.6-0.8-0.5-0.5-0.51.9-1.9-0.7-0.6-1.0-0.7-0.60.0-0.5-1.10.6-1.2
Patch foraging water rate 0 sec1.32.65.72.31.71.6-1.51.72.1-1.61.71.41.41.4-2.42.41.81.71.51.71.50.91.40.90.70.8
Patch foraging water rate 12 sec1.02.03.9-0.8-1.3-1.01.3-1.3-1.31.6-1.6-1.6-1.6-1.6-1.31.3-1.5-1.5-1.5-1.5-1.7-2.0-1.8-0.5-1.11.3
Patch foraging water rate 18 sec0.50.73.50.2-0.20.30.2-0.0-0.30.5-0.6-0.6-0.6-0.6-1.41.4-0.5-0.9-0.4-1.0-0.6-1.0-0.70.9-1.91.4
Patch foraging water rate 24 sec0.20.32.2-0.2-0.00.4-0.1-0.0-0.10.4-0.3-0.4-0.4-0.4-0.10.1-0.3-0.5-0.3-0.6-0.4-0.4-0.50.8-1.51.3
Patch foraging water rate 6 sec0.30.42.00.3-0.00.10.1-0.10.20.4-0.6-0.6-0.6-0.6-1.41.4-0.3-0.6-0.2-0.5-0.4-0.7-0.50.2-0.91.1
Seeking ratio, delayed vs. immediate footshock0.20.21.50.3-0.2-0.50.30.0-0.0-0.20.10.20.20.2-0.80.80.50.2-0.20.20.10.00.0-1.11.2-0.8
Distance traveled before self-admin0.60.83.9-0.9-0.7-0.10.4-0.6-0.80.9-1.0-0.8-0.8-0.80.5-0.5-1.2-1.1-0.4-1.1-0.9-0.8-1.00.7-2.00.9
Distance traveled after self-admin0.20.33.4-0.1-0.10.5-0.10.00.00.20.1-0.1-0.1-0.10.2-0.2-0.5-0.40.4-0.2-0.3-0.2-0.51.0-1.80.6
Extensor digitorum longus weight1.04.018.4-2.2-2.6-3.52.3-2.0-1.31.4-1.4-1.6-1.6-1.61.1-1.1-0.8-0.9-2.2-1.0-1.0-1.4-1.0-4.33.5-1.6
Bone: elastic displacement2.52.94.5-1.4-1.8-1.71.8-1.7-2.11.8-2.0-1.9-1.9-1.9-0.80.8-2.0-2.0-1.9-2.1-1.9-2.1-1.7-1.2-0.8-0.3
Bone: elastic work0.50.73.20.1-0.5-0.70.7-0.6-0.60.6-0.7-0.8-0.8-0.8-1.81.8-0.6-0.7-0.6-0.8-0.6-0.8-0.4-1.00.0-0.5
Bone: endosteal estimation13.229.040.55.46.26.4-6.05.95.8-6.06.16.16.16.10.6-0.65.65.76.05.75.96.35.85.10.30.2
Bone: endosteal perimeter14.731.249.15.76.67.0-6.56.45.7-6.16.16.16.16.1-0.40.45.85.95.95.86.26.06.16.0-0.41.2
Epididymis fat weight0.41.22.51.41.11.0-1.11.21.4-1.11.11.11.11.1-1.11.11.61.20.91.41.20.91.10.41.00.4
Delta time in closed arm before/after self-admin0.30.31.0-0.8-0.3-0.30.5-0.7-0.60.6-0.5-0.4-0.4-0.41.0-1.0-0.7-0.1-0.6-0.2-0.5-0.1-0.2-0.3-0.50.0
Delta time in open arm before/after self-admin0.20.20.60.3-0.2-0.3-0.10.30.7-0.40.40.10.10.1-0.40.40.50.50.60.60.4-0.10.2-0.20.8-0.1
Diff in mean of infusions in LGA sessions1.72.04.5-1.4-1.9-2.11.9-1.7-1.61.2-1.3-1.1-1.1-1.10.1-0.1-1.4-1.5-1.3-1.6-1.5-1.4-1.5-1.90.8-1.1
Delay discount exponential model param0.30.42.5-0.5-0.7-0.90.9-0.6-0.50.20.0-0.1-0.1-0.10.7-0.7-0.4-0.3-0.0-0.4-0.5-0.1-0.3-1.00.6-1.6
Extinction: sum of active levers before priming0.10.20.70.40.30.2-0.40.30.8-0.40.50.40.40.4-0.50.50.20.30.70.40.30.10.00.30.10.1
Active lever presses in extinction session 61.51.52.41.51.41.0-1.21.11.3-1.41.31.51.51.5-0.80.81.21.21.51.51.21.31.00.50.9-0.7
Bone: final force0.50.93.60.90.81.3-0.90.60.40.00.1-0.1-0.1-0.1-1.91.9-0.1-0.10.2-0.10.1-0.20.11.3-1.61.8
Bone: final moment0.50.83.60.90.71.2-0.70.50.40.10.0-0.1-0.1-0.1-1.91.9-0.2-0.20.2-0.20.0-0.30.01.2-1.61.6
Food consumed during 24 hour testing period2.83.86.12.22.01.6-1.72.12.5-2.32.12.22.22.2-1.71.72.42.11.92.12.11.72.10.81.5-0.4
Glucose1.01.52.9-1.3-1.3-1.01.2-1.1-1.71.4-1.4-1.3-1.3-1.3-0.00.0-1.5-1.5-1.3-1.5-1.5-1.4-1.6-0.0-0.80.4
Heart weight0.60.94.0-0.3-0.30.20.2-0.5-0.40.9-1.1-1.1-1.1-1.1-1.31.3-0.7-0.7-0.9-0.8-0.7-1.3-0.90.3-1.12.0
Delay discount hyperbolic model param0.30.42.5-0.4-0.8-1.00.9-0.6-0.40.10.0-0.1-0.1-0.10.6-0.6-0.4-0.4-0.0-0.5-0.5-0.2-0.4-1.00.7-1.6
Intermittent access intake day 1-15 change0.20.42.0-0.5-0.1-0.40.4-0.30.1-0.20.40.30.30.31.4-1.40.00.00.20.00.10.40.4-0.61.1-1.3
Intermittent access intake escalation0.20.41.10.10.40.2-0.20.30.5-0.60.80.80.80.81.0-1.00.50.50.60.50.50.80.7-0.11.0-1.0
Intermittent access intake escalation 20.70.82.00.10.50.2-0.20.40.7-0.81.00.90.90.91.4-1.40.70.70.80.80.81.21.0-0.21.2-1.3
Intermitt. access day 1 inactive lever presses0.93.34.82.12.01.5-1.71.82.2-2.22.12.12.12.1-0.70.72.11.82.11.72.02.02.00.61.6-1.3
Intermitt. access day 15 inactive lever presses0.91.97.71.30.8-0.1-0.50.91.9-1.51.31.41.41.4-0.00.01.71.21.61.11.21.51.5-1.12.8-2.0
Intermitt. access escalation Index1.82.54.7-1.8-1.7-1.01.3-1.3-2.01.7-1.8-1.5-1.5-1.51.0-1.0-1.8-2.1-1.7-2.0-1.7-1.6-1.90.0-2.20.9
Intermittent access day 1 total infusions1.01.65.61.81.41.5-1.41.31.2-1.11.01.01.01.0-2.42.40.90.81.20.80.80.40.51.5-0.60.9
Intermittent access day 15 total infusions1.42.23.91.81.71.6-1.51.62.0-1.61.71.51.51.5-1.31.31.51.41.81.41.41.11.31.20.50.1
Intermittent access terminal intake (last 3 days)2.83.76.12.22.32.1-2.12.12.5-2.22.32.12.12.1-1.01.02.11.92.32.02.01.82.01.60.40.2
Intermittent access total infusions3.13.76.02.42.32.3-2.22.22.2-2.02.11.91.91.9-2.12.11.91.72.11.81.71.31.62.0-0.20.8
Intermittent access day 1 locomotion3.24.18.72.92.32.0-2.12.02.3-2.22.02.02.02.0-2.92.91.91.92.31.91.71.41.51.40.8-0.1
Intermittent access day 15 total locomotion3.56.39.73.13.12.7-2.82.72.7-2.72.82.62.62.6-2.42.42.72.62.72.72.42.22.41.90.8-0.1
Intermittent access total locomotion7.48.916.04.03.53.1-3.23.13.2-3.13.23.03.03.0-3.73.73.03.03.13.12.72.32.52.21.1-0.0
Intermittent access standard deviation0.40.81.70.90.90.4-0.60.61.2-1.01.21.01.01.0-0.40.40.91.01.11.00.90.91.1-0.21.3-1.0
Left kidney weight0.31.44.20.0-0.50.20.5-0.4-1.00.9-1.1-0.9-0.9-0.9-2.02.0-0.9-1.1-1.2-0.8-1.1-1.6-1.20.6-1.62.0
Right kidney weight0.31.24.50.2-0.10.90.20.1-0.70.7-0.9-0.6-0.6-0.6-2.12.1-0.5-0.9-0.8-0.7-0.7-1.4-0.61.3-2.02.1
Cocaine induced anxiety0.71.02.2-0.9-0.9-0.71.1-1.0-0.91.1-1.2-1.2-1.2-1.2-0.00.0-1.1-1.5-0.9-1.4-1.2-1.2-1.0-0.3-0.50.3
Post-drug Anxiety1.11.22.1-1.0-1.0-0.81.2-1.2-1.11.3-1.3-1.3-1.3-1.3-0.00.0-1.2-1.3-1.2-1.4-1.4-1.3-1.0-0.6-0.70.4
Baseline Anxiety0.20.20.8-0.2-0.3-0.70.4-0.5-0.30.4-0.4-0.4-0.4-0.4-0.30.3-0.30.2-0.50.0-0.5-0.3-0.4-0.90.4-0.2
Tail length2.18.013.13.63.53.1-3.22.92.8-2.92.92.92.92.9-2.42.43.03.52.73.52.82.82.82.01.20.1
Length with tail1.87.915.53.03.73.9-3.63.32.3-2.72.72.72.72.7-1.31.32.83.22.23.33.12.93.13.3-0.41.3
Length without tail0.20.72.30.41.11.5-1.11.10.5-0.60.70.50.50.50.3-0.30.60.90.30.91.21.01.21.5-0.60.8
Times rat made contact with spout0.60.71.30.80.91.0-0.80.90.8-1.00.91.11.11.1-0.00.01.00.80.70.81.01.01.10.7-0.1-0.3
Lifetime Intake3.54.27.72.82.42.3-2.22.32.3-2.12.22.02.02.0-2.72.72.11.92.22.01.81.31.51.90.10.7
Liver weight, left3.35.511.12.52.93.3-2.72.91.6-2.52.32.72.72.7-0.80.82.12.12.32.22.32.42.43.3-1.30.3
Liver weight, right1.22.13.5-0.7-1.2-0.91.3-1.2-1.71.7-1.7-1.6-1.6-1.6-1.51.5-1.4-1.5-1.7-1.2-1.9-1.9-1.7-0.6-0.61.1
Locomotor activity1.01.58.51.80.80.9-0.60.91.4-1.11.21.21.21.2-2.92.90.80.41.30.30.40.10.10.80.0-0.2
Locomotor testing distance1.22.27.92.31.10.9-0.81.11.9-1.61.51.71.71.7-2.82.81.31.01.80.80.70.60.40.41.0-0.9
Locomotor testing rearing1.12.37.31.70.90.2-0.40.81.8-1.71.92.02.02.0-0.70.71.41.12.21.20.81.40.7-0.62.3-2.7
Locomotion in novel chamber0.30.42.9-0.50.10.6-0.0-0.1-0.90.5-0.5-0.3-0.3-0.30.8-0.8-0.5-0.6-0.5-0.4-0.4-0.1-0.20.9-1.70.5
Locomotion in novel chamber post-restriction1.32.17.90.91.72.3-2.11.51.3-0.91.10.70.70.70.3-0.30.81.21.01.31.51.21.32.8-1.82.4
Fecal boli incidents, locomotor time 10.10.21.2-0.20.10.3-0.30.20.4-0.10.20.00.00.01.1-1.10.10.30.50.20.40.40.30.6-0.30.2
Change in fecal boli incidents, locomotor task0.10.10.6-0.2-0.2-0.40.1-0.1-0.20.3-0.4-0.2-0.2-0.2-0.30.30.30.1-0.70.1-0.1-0.10.0-0.70.80.5
Time >=10cm from walls, locomotor time 12.22.44.9-1.8-1.6-1.11.3-1.5-1.81.7-1.5-1.6-1.6-1.61.1-1.1-1.9-1.8-1.4-1.8-1.7-1.5-1.7-0.2-2.20.7
Bouts of movement, locomotor time 10.60.72.8-0.6-0.8-1.21.0-0.8-0.40.7-0.7-0.8-0.8-0.80.1-0.1-0.3-0.6-0.8-0.5-0.7-0.7-0.5-1.61.7-0.7
Total resting periods, locomotor time 10.60.72.7-0.7-0.9-1.21.0-0.8-0.60.8-0.8-0.9-0.9-0.90.3-0.3-0.3-0.5-0.9-0.5-0.7-0.7-0.4-1.61.6-0.5
Rest time, locomotor task time 10.30.42.5-0.9-0.6-0.50.5-0.3-0.30.2-0.5-0.3-0.3-0.31.6-1.6-0.1-0.3-0.3-0.20.00.20.2-0.50.3-0.2
Distance moved, locomotor task time 10.20.31.10.80.80.5-0.70.30.3-0.50.60.50.50.5-1.11.10.40.60.00.60.30.30.30.20.6-0.2
Vertical activity count, locomotor time 10.10.20.60.70.60.7-0.60.20.4-0.30.40.40.40.4-0.80.80.10.30.20.20.20.20.20.4-0.30.3
Time >=10cm from walls, locomotor time 20.40.62.4-1.0-0.6-0.70.7-0.8-0.60.4-0.5-0.3-0.3-0.31.5-1.5-0.8-0.8-0.1-0.8-0.7-0.1-0.3-0.3-0.6-0.9
Bouts of movement, locomotor time 20.40.62.4-0.4-0.9-1.30.7-0.7-0.40.6-0.6-0.7-0.7-0.7-0.30.3-0.3-0.2-0.6-0.2-0.5-0.6-0.7-1.61.5-0.6
Total resting periods, locomotor time 20.40.72.5-0.5-1.1-1.40.9-0.9-0.70.8-0.8-0.9-0.9-0.9-0.30.3-0.5-0.3-0.8-0.4-0.8-0.8-1.0-1.61.3-0.5
Rest time, locomotor task time 22.53.25.4-2.3-2.1-1.71.7-1.8-1.81.9-2.1-2.0-2.0-2.01.7-1.7-1.9-1.7-1.9-1.8-1.6-1.8-1.7-1.2-1.00.8
Distance moved, locomotor task time 20.30.42.90.50.70.0-0.20.10.1-0.50.70.70.70.7-0.10.10.40.50.30.60.20.90.5-0.41.2-1.7
Vertical activity count, locomotor time 21.42.03.61.71.40.7-0.91.01.4-1.71.61.81.81.8-0.80.81.21.41.61.51.21.61.40.01.5-1.9
Light reinforcement 10.51.18.81.40.50.3-0.60.71.1-0.50.20.30.30.3-3.03.00.80.60.60.70.5-0.40.0-0.10.70.8
Light reinforcement 20.50.84.51.10.70.6-0.80.71.0-0.60.20.50.50.5-2.12.10.70.80.40.70.8-0.10.50.30.31.0
Bone: marrow area12.727.738.85.26.16.2-5.85.85.7-5.86.06.06.06.00.8-0.85.55.65.95.55.86.25.75.00.30.2
Bone: maximum diameter3.56.613.83.03.13.7-3.13.12.5-2.52.42.52.52.5-1.61.62.42.42.32.32.72.32.53.5-1.21.6
Bone: maximum force1.22.18.21.91.62.1-1.71.31.0-0.50.60.40.40.4-2.92.90.80.70.40.80.80.30.41.8-1.32.7
Bone: maximum moment1.01.87.71.81.51.9-1.51.21.0-0.50.50.30.30.3-2.82.80.80.60.40.70.70.20.51.6-1.22.3
Mean time between licks in bursts0.10.31.40.30.60.7-0.70.50.8-0.20.40.10.10.1-0.20.20.40.40.40.40.60.30.50.6-0.51.2
Mean num. licks in bursts0.30.42.40.70.40.1-0.20.50.3-0.60.50.60.60.6-0.50.50.90.70.20.60.60.50.8-0.41.6-0.6
Cd content in liver2.83.110.6-2.5-2.1-2.22.0-1.7-1.71.3-1.4-1.3-1.3-1.33.3-3.3-1.4-1.5-1.5-1.4-1.1-1.0-0.7-1.90.7-1.0
Co content in liver0.80.92.3-1.3-1.4-1.31.2-0.9-1.50.5-0.8-0.6-0.6-0.60.9-0.9-1.1-1.1-1.2-0.9-0.6-0.9-0.5-0.8-0.3-1.2
Cu content in liver0.30.40.90.40.40.3-0.40.60.4-0.90.50.80.80.80.3-0.30.70.60.40.50.90.80.90.00.7-0.7
Fe content in liver0.10.11.00.20.10.4-0.30.1-0.5-0.10.20.20.20.2-0.40.4-0.4-0.00.4-0.0-0.00.3-0.40.8-1.0-0.3
K content in liver0.80.74.10.60.81.5-1.01.10.4-0.60.60.70.70.7-0.30.30.40.20.60.30.80.40.62.0-1.60.9
Mg content in liver0.20.20.6-0.8-0.6-0.30.4-0.1-0.60.3-0.4-0.3-0.3-0.30.6-0.6-0.5-0.7-0.5-0.3-0.1-0.4-0.10.2-0.7-0.1
Mn content in liver0.60.64.1-0.2-0.20.50.0-0.1-0.70.6-0.6-0.5-0.5-0.5-0.70.7-0.8-0.9-0.6-0.7-0.5-0.8-0.71.5-2.01.3
Na content in liver0.80.92.80.80.71.2-0.91.20.3-1.20.81.31.31.3-0.50.50.60.50.80.61.00.70.71.7-1.0-0.4
Rb content in liver3.23.87.5-2.3-2.2-1.62.0-1.8-2.72.1-2.1-2.0-2.0-2.00.7-0.7-2.3-2.4-2.5-2.2-2.0-2.0-2.1-0.4-1.70.3
Se content in liver0.81.02.7-0.4-0.8-0.20.3-0.3-1.30.8-1.1-0.9-0.9-0.9-1.21.2-0.9-0.9-1.1-1.0-0.7-1.4-1.20.7-1.61.4
Sr content in liver0.40.30.70.70.60.6-0.50.80.5-0.60.50.60.60.6-0.60.60.60.50.60.50.60.40.80.6-0.10.0
Zn content in liver0.40.51.1-0.8-0.6-0.30.6-0.3-1.10.6-0.9-0.6-0.6-0.60.3-0.3-0.6-0.9-1.0-0.8-0.6-0.7-0.50.3-1.00.8
Bone: minimum diameter10.719.630.15.15.45.5-5.25.14.9-4.74.74.64.64.6-2.02.04.64.74.74.64.94.44.74.40.21.0
Time in familiar zone, hab. session 11.11.11.80.71.00.9-1.11.11.0-1.11.31.21.21.20.9-0.91.31.21.00.81.31.31.10.60.80.0
Time in novel zone, hab. session 11.71.72.7-0.9-1.5-1.61.5-1.4-1.31.4-1.5-1.5-1.5-1.5-0.80.8-1.5-1.4-1.4-1.0-1.6-1.6-1.5-1.2-0.3-0.1
Total zone transitions, hab. session 10.30.43.00.80.50.4-0.30.30.4-0.20.30.10.10.1-1.71.70.40.20.20.10.1-0.2-0.10.30.20.7
Total locomotion distance, hab. session 10.60.85.91.40.90.8-0.60.50.6-0.40.40.30.30.3-2.42.40.60.50.30.80.20.10.20.30.40.7
Locomotion velocity, hab. session 10.81.14.31.51.41.3-1.10.91.0-0.70.80.60.60.6-2.12.10.90.80.71.10.60.60.60.80.30.8
Time in familiar zone, hab. session 21.71.83.21.21.41.2-1.31.41.2-1.71.81.81.81.80.5-0.51.51.51.61.21.51.51.40.80.5-0.7
Time in novel zone, hab. session 22.02.13.9-1.2-1.4-1.21.3-1.5-1.21.8-1.9-2.0-2.0-2.0-0.30.3-1.5-1.6-1.8-1.2-1.6-1.5-1.5-0.7-0.61.2
Total zone transitions, hab. session 20.20.21.30.60.40.4-0.30.30.4-0.40.50.30.30.3-1.11.10.30.20.40.00.20.00.00.40.20.1
Total locomotion distance, hab. session 20.50.73.01.20.90.6-0.70.60.9-0.60.80.40.40.4-1.71.70.80.80.50.90.60.30.50.21.10.5
Locomotion velocity, hab. session 20.50.72.71.10.90.8-0.80.70.8-0.50.70.30.30.3-1.71.70.80.70.40.90.60.30.40.40.90.8
Novel to familiar place preference ratio0.20.20.70.60.50.5-0.40.50.3-0.20.30.30.30.3-0.80.80.40.40.20.40.30.10.40.6-0.10.3
Novelty place preference0.10.10.50.40.20.3-0.20.30.0-0.10.10.20.20.2-0.70.70.20.2-0.00.20.0-0.00.10.4-0.10.2
Time in novel zone, NPP test0.10.10.50.30.10.2-0.00.2-0.10.0-0.00.10.10.1-0.70.7-0.00.0-0.20.0-0.2-0.2-0.00.4-0.20.2
Total zone transitions, NPP test0.60.86.00.80.50.8-0.40.30.20.10.0-0.2-0.2-0.2-2.42.40.10.0-0.1-0.0-0.1-0.6-0.40.9-0.61.6
Total locomotion distance, NPP test0.50.72.91.21.11.0-0.80.60.8-0.40.60.20.20.2-1.71.70.70.70.40.70.40.30.30.60.41.1
Locomotion velocity, NPP test0.60.95.01.21.00.9-0.80.61.0-0.30.50.10.10.1-2.22.20.80.80.30.80.50.10.30.40.71.3
Intraocular pressure0.81.14.51.50.70.3-0.60.61.4-0.80.60.50.50.5-1.91.91.41.21.01.00.70.40.4-0.42.10.3
Delta distance traveled before/after self-admin0.10.21.00.4-0.1-0.30.1-0.20.1-0.10.40.10.10.1-1.01.0-0.10.10.20.1-0.2-0.2-0.4-0.50.2-0.6
Delta ambulatory time before/after self-admin0.20.20.70.70.40.3-0.40.30.6-0.40.70.40.40.4-0.80.80.40.50.50.60.30.30.1-0.00.2-0.2
Parametrial fat weight0.30.63.3-0.50.50.9-0.30.50.3-0.3-0.20.30.30.31.8-1.80.2-0.2-0.0-0.30.60.41.21.0-0.91.0
Pavlov. Cond. lever latency1.31.63.6-1.7-1.4-1.41.2-1.3-0.91.3-1.1-1.4-1.4-1.41.9-1.9-1.0-1.0-1.3-0.9-1.0-0.9-0.9-1.10.01.0
Pavlov. Cond. magazine entry latency2.83.65.52.32.12.1-2.02.21.5-2.21.92.32.32.3-1.61.61.91.91.91.92.01.81.91.70.3-0.9
Pavlov. Cond. change in total contacts2.42.64.12.01.51.3-1.31.71.3-1.91.62.02.02.0-1.61.61.51.61.81.61.61.51.50.90.8-1.8
Pavlov. Cond. index score2.53.25.32.31.92.0-1.92.11.3-2.01.82.12.12.1-1.81.81.71.71.81.61.81.51.61.70.0-0.9
Pavlov. Cond. latency score2.22.74.72.21.81.9-1.71.91.2-1.91.62.02.02.0-1.91.91.51.51.61.51.61.31.41.6-0.1-0.9
Pavlov. Cond. lever contacts1.61.93.01.61.51.4-1.21.41.1-1.61.41.71.71.7-1.11.11.21.31.51.11.31.41.30.90.4-1.6
Pavlov. Cond. magazine entry number2.22.84.2-2.0-1.8-1.81.8-2.0-1.42.0-1.6-2.0-2.0-2.01.3-1.3-1.6-1.6-1.8-1.7-1.8-1.6-1.7-1.4-0.31.1
Pavlov. Cond. intertrial magazine entries1.82.14.21.91.51.4-1.71.51.9-1.31.41.11.11.1-2.02.01.71.71.41.41.50.90.80.90.51.3
Pavlov. Cond. lever-magazine prob. diff.2.43.05.02.21.92.0-1.82.01.2-1.91.62.02.02.0-1.91.91.61.61.61.61.71.51.51.7-0.0-0.8
Pavlov. Cond. response bias2.93.65.52.32.22.3-2.02.21.6-2.11.82.22.22.2-1.51.51.81.72.01.71.91.91.91.80.0-1.0
Pavlov. Cond. lever latency0.40.61.3-1.0-0.9-1.10.9-0.9-0.70.7-0.7-0.8-0.8-0.80.7-0.7-0.7-0.6-0.9-0.7-0.6-0.6-0.4-1.10.5-0.3
Pavlov. Cond. magazine entry latency1.92.33.6-1.9-1.5-1.01.3-1.4-1.71.7-1.5-1.6-1.6-1.61.1-1.1-1.9-1.9-1.2-1.8-1.7-1.5-1.7-0.2-1.80.6
Pavlov. Cond. change in total contacts0.81.22.41.01.21.4-1.31.40.9-1.21.31.41.41.40.0-0.01.10.91.31.11.11.20.91.6-0.5-0.1
Pavlov. Cond. index score0.10.11.20.10.20.5-0.30.3-0.1-0.10.10.20.20.20.1-0.1-0.1-0.20.4-0.1-0.10.1-0.20.9-1.10.2
Pavlov. Cond. latency score0.10.21.7-0.20.00.4-0.10.0-0.30.2-0.1-0.0-0.0-0.00.1-0.1-0.4-0.50.2-0.3-0.3-0.1-0.40.8-1.30.2
Pavlov. Cond. lever contacts0.30.51.00.90.80.9-0.80.80.6-0.60.60.70.70.7-1.01.00.60.60.80.60.50.40.30.8-0.30.2
Pavlov. Cond. magazine entry number2.73.45.52.21.81.3-1.71.82.0-2.11.92.02.02.0-1.21.22.32.31.52.32.21.92.10.32.0-0.5
Pavlov. Cond. intertrial magazine entries9.714.522.14.44.23.5-4.04.24.2-4.34.14.14.14.1-1.51.54.74.63.74.34.54.14.51.92.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.21.6-0.10.10.5-0.10.1-0.20.1-0.00.00.00.00.2-0.2-0.3-0.40.3-0.3-0.2-0.1-0.30.9-1.30.4
Pavlov. Cond. response bias0.10.20.80.40.40.7-0.50.40.2-0.10.20.20.20.2-0.50.50.10.00.40.10.10.1-0.10.9-0.90.6
Time in closed arm before self-admin0.30.31.70.2-0.4-0.60.5-0.6-0.50.1-0.2-0.2-0.2-0.2-1.31.3-0.5-0.6-0.1-0.4-0.6-0.6-0.6-0.80.2-0.8
Time in closed arm after self-admin0.80.81.8-1.1-0.8-0.71.0-1.2-1.30.9-0.8-0.8-0.8-0.80.7-0.7-1.2-1.1-1.0-1.1-1.0-0.7-0.7-0.7-0.9-0.3
Time in open arm before self-admin1.41.52.4-1.5-0.9-0.61.0-1.1-1.51.5-1.5-1.2-1.2-1.21.0-1.0-1.5-1.4-1.3-1.5-1.4-1.1-1.2-0.0-1.30.6
Time in open arm after self-admin0.20.20.60.40.50.4-0.60.80.7-0.40.40.40.40.40.0-0.00.70.60.60.60.60.40.40.60.40.4
Bone: periosteal estimation7.014.724.44.54.74.9-4.54.44.2-4.14.14.14.14.1-1.81.83.93.94.13.84.13.93.94.0-0.41.0
Bone: periosteal perimeter3.86.514.22.93.13.8-3.13.12.5-2.52.42.52.52.5-1.61.62.22.22.52.12.62.12.63.6-1.51.3
Bone: post-yield work1.11.63.41.41.71.8-1.51.41.3-1.31.41.31.31.3-0.10.11.21.21.21.41.31.51.21.4-0.40.8
Progressive ratio test 1 active lever presses2.83.58.02.62.11.9-1.91.92.4-1.91.81.61.61.6-2.82.81.81.72.11.81.61.01.31.50.40.6
Progressive ratio test 1 breakpoint3.34.08.32.82.22.1-2.12.12.5-2.02.01.81.81.8-2.92.92.01.92.22.01.71.21.41.60.60.6
Progressive ratio test 1 inactive lever presses3.04.38.42.92.42.1-2.22.22.5-2.22.22.02.02.0-2.62.62.11.92.41.91.81.41.51.70.30.4
Progressive ratio test 2 active lever presses5.16.010.23.03.03.0-2.82.83.2-2.62.52.32.32.3-2.02.02.62.42.82.42.52.02.32.40.10.9
Progressive ratio test 2 breakpoint5.66.510.73.13.13.1-2.92.93.3-2.72.62.52.52.5-1.91.92.72.53.02.52.62.12.42.50.10.9
Progressive ratio test 2 inactive lever presses2.23.66.92.62.21.8-1.92.02.4-2.01.91.71.71.7-2.52.52.21.91.91.91.81.21.61.11.00.6
Incentive Sensitization - Responses2.73.87.02.12.42.6-2.32.32.2-2.02.02.02.02.0-0.60.62.11.92.11.82.11.82.02.3-0.30.9
Incentive Sensitization - Breakpoint2.93.87.12.12.52.7-2.32.32.2-2.02.02.02.02.0-0.50.52.11.92.11.82.11.92.12.4-0.40.9
Sum of active levers in priming session hrs 5-60.30.31.0-0.4-1.0-1.00.8-0.6-0.10.2-0.3-0.1-0.1-0.1-0.10.1-0.5-0.70.1-0.6-0.5-0.7-0.9-0.70.3-0.6
Progressive ratio0.30.42.1-0.10.51.0-0.70.40.1-0.10.1-0.0-0.0-0.00.9-0.90.00.00.20.10.50.20.41.4-1.21.3
Food seeking constrained by brief footshock3.34.06.81.62.11.9-1.82.01.8-2.42.52.62.62.61.0-1.02.11.92.11.82.22.62.41.31.0-1.4
Seeking ratio, punishment vs. effort1.31.93.21.61.20.7-0.91.21.2-1.61.61.81.81.8-0.70.71.51.51.41.51.21.61.3-0.11.5-1.7
Retroperitoneal fat weight0.31.42.81.31.41.0-1.01.21.4-1.21.11.21.21.2-0.90.91.71.40.91.41.21.11.50.21.40.0
Reaction time number correct0.61.15.1-0.8-0.60.00.5-0.5-0.61.2-1.3-1.3-1.3-1.3-0.30.3-0.9-1.3-1.0-1.2-1.0-1.4-1.00.6-1.22.3
Reaction time mean minus median0.30.71.9-1.0-0.7-1.10.7-0.8-0.60.7-0.6-0.8-0.8-0.81.4-1.4-0.5-0.4-0.6-0.3-0.6-0.2-0.4-1.11.1-0.9
Reaction time mean minus median AUC0.61.52.4-1.4-1.3-1.21.0-1.2-1.41.5-1.4-1.5-1.5-1.50.5-0.5-1.4-1.3-1.6-1.2-1.3-1.2-1.3-0.6-0.30.4
Reaction time num false alarms2.94.17.52.52.52.7-2.42.21.9-2.02.02.22.22.2-1.81.81.82.12.11.91.91.71.62.3-0.80.8
Reaction time num false alarms AUC2.84.48.62.52.62.9-2.52.42.0-2.12.12.22.22.2-1.61.61.92.12.11.92.01.81.82.5-0.80.9
Reaction time trials correct on left0.61.15.1-0.8-0.60.00.5-0.5-0.61.2-1.3-1.3-1.3-1.3-0.30.3-0.9-1.3-1.0-1.2-1.0-1.4-1.00.6-1.22.3
Reaction time trials on left0.61.25.5-0.8-0.60.10.5-0.5-0.61.2-1.4-1.3-1.3-1.3-0.30.3-0.9-1.3-1.0-1.2-1.0-1.4-1.00.6-1.22.4
Reaction time mean0.81.32.3-1.4-1.2-1.31.1-1.4-1.21.3-1.0-1.2-1.2-1.21.5-1.5-1.3-1.1-1.0-1.1-1.2-0.7-1.2-0.8-0.4-0.3
Reaction time mean AUC1.11.83.0-1.7-1.6-1.61.4-1.6-1.41.4-1.2-1.3-1.3-1.31.7-1.7-1.4-1.3-1.1-1.3-1.4-0.8-1.4-1.2-0.2-0.7
Median of all reaction times0.91.32.0-1.3-1.3-1.21.1-1.4-1.21.2-1.1-1.1-1.1-1.11.3-1.3-1.3-1.2-1.0-1.3-1.2-0.8-1.3-0.7-0.7-0.2
Reaction time omissions0.10.21.4-0.00.2-0.2-0.1-0.2-0.00.2-0.2-0.3-0.3-0.30.7-0.70.20.2-0.20.40.10.40.2-0.61.20.4
Reaction time false alarm rate3.14.26.32.32.42.3-2.32.21.9-2.32.42.52.52.5-1.01.02.02.42.22.12.12.22.01.7-0.0-0.6
Reaction time premature initiation rate0.91.23.81.50.70.6-0.60.91.5-1.21.00.90.90.9-1.91.91.20.91.11.11.10.60.9-0.11.4-0.2
Reaction time premature initiations0.40.73.51.10.50.7-0.50.71.1-0.60.30.30.30.3-1.91.90.80.30.60.50.7-0.00.50.40.61.0
Std. dev. reaction times0.61.04.4-1.3-0.8-1.10.8-1.0-1.01.0-0.7-0.9-0.9-0.92.1-2.1-0.7-0.6-0.9-0.5-0.7-0.2-0.5-1.00.6-0.7
Reaction time trials completed0.61.25.5-0.8-0.60.10.5-0.5-0.61.2-1.4-1.3-1.3-1.3-0.30.3-0.9-1.3-1.0-1.2-1.0-1.4-1.00.6-1.22.4
Reaction time trials AUC0.61.15.4-0.8-0.60.00.5-0.5-0.61.2-1.3-1.3-1.3-1.3-0.20.2-0.9-1.3-1.0-1.2-1.0-1.4-1.00.5-1.12.3
Run reversals in cocaine runway, females1.21.25.2-0.9-1.2-1.61.4-1.1-0.60.8-1.0-0.8-0.8-0.80.6-0.6-0.4-0.7-1.1-0.7-0.7-0.8-0.3-2.31.9-1.1
Run reversals in cocaine runway, males0.20.20.3-0.5-0.2-0.20.2-0.4-0.40.5-0.5-0.5-0.5-0.50.6-0.6-0.5-0.2-0.5-0.1-0.3-0.2-0.20.1-0.50.3
Latency to leave start box in cocaine runway0.20.20.5-0.4-0.7-0.60.6-0.6-0.40.5-0.4-0.5-0.5-0.5-0.20.2-0.6-0.4-0.3-0.4-0.5-0.4-0.7-0.5-0.1-0.1
Latency to leave start box in cocaine runway, F0.70.81.8-0.5-0.9-0.80.8-1.0-1.01.0-1.0-1.0-1.0-1.0-0.80.8-1.1-0.9-0.9-0.8-1.1-0.8-1.3-0.5-0.50.0
Latency to leave start box in cocaine runway, M0.30.30.9-0.0-0.1-0.00.10.20.6-0.50.60.60.60.60.9-0.90.30.30.80.30.50.60.6-0.30.4-0.8
Std. dev. time between licks in bursts0.10.10.40.10.1-0.3-0.1-0.10.40.00.2-0.0-0.0-0.0-0.20.20.20.30.10.40.10.10.1-0.70.6-0.3
Total sessions with >9 infusions0.81.08.51.40.40.3-0.40.40.8-0.50.40.30.30.3-2.92.90.40.40.60.50.2-0.5-0.20.10.40.2
Short access day 1 total inactive lever presses1.41.96.02.11.61.2-1.21.31.2-1.41.21.11.11.1-2.42.41.51.41.01.51.00.91.10.60.70.1
Short access day 10 total inactive lever presses0.10.22.00.40.1-0.4-0.00.00.7-0.30.30.10.10.1-0.30.30.60.30.20.10.30.20.4-1.01.4-0.4
Short access day 1 total infusions1.21.613.51.80.50.5-0.60.80.8-0.70.50.50.50.5-3.73.70.70.60.50.70.3-0.5-0.30.4-0.10.5
Short access day 10 total infusions3.03.99.02.82.01.7-1.91.92.2-2.02.11.91.91.9-3.03.02.02.02.12.11.61.21.31.20.90.1
Short access total infusions1.72.28.62.21.31.2-1.21.41.5-1.41.41.31.31.3-2.92.91.31.21.51.31.00.50.60.90.30.2
Short access day 1 locomotion2.73.418.52.81.40.9-1.51.42.0-1.41.31.11.11.1-4.34.31.61.61.51.91.20.30.60.41.40.4
Short access day 10 total locomotion3.87.111.13.32.92.1-2.62.52.8-3.02.92.92.92.9-2.42.42.83.02.93.02.72.52.50.92.7-1.5
Short access total locomotion3.34.012.82.92.01.3-1.91.62.1-1.91.81.71.71.7-3.63.61.92.11.92.31.61.11.20.41.9-0.6
One hour access (0.3 mA shock)1.21.32.01.41.31.4-1.31.31.3-1.31.31.31.31.3-0.60.61.21.11.31.21.21.11.01.4-0.30.2
Compulsive drug intake1.11.32.8-1.4-0.9-0.40.9-0.9-1.51.3-1.4-1.1-1.1-1.11.1-1.1-1.2-1.4-1.4-1.3-1.2-0.9-1.00.2-1.70.9
One hour access (shock baseline)1.62.43.91.91.71.5-1.71.62.0-1.71.91.61.61.6-1.21.21.61.71.91.61.61.31.41.00.7-0.1
Social response proportion0.20.20.5-0.5-0.5-0.40.5-0.4-0.30.6-0.5-0.7-0.7-0.70.2-0.2-0.2-0.7-0.6-0.6-0.5-0.4-0.4-0.30.10.2
Social responses0.10.20.90.60.10.20.00.40.5-0.20.40.20.20.2-1.01.00.5-0.00.50.20.00.0-0.00.20.1-0.2
Social time0.20.32.9-0.4-0.3-0.10.3-0.00.2-0.1-0.10.20.20.21.7-1.70.1-0.40.2-0.30.20.40.40.10.3-0.5
Soleus weight0.10.42.50.90.40.7-0.60.80.1-0.50.20.50.50.5-1.61.60.30.20.30.10.4-0.00.20.7-0.30.1
Bone: stiffness0.91.56.61.21.42.1-1.61.20.7-0.50.70.50.50.5-1.51.50.60.40.40.50.60.30.22.2-2.02.6
Tibialis anterior weight0.41.48.40.80.1-0.7-0.20.60.7-1.20.91.01.01.0-1.11.11.31.20.41.01.20.61.1-1.62.9-1.9
Time to tail flick, vehicle, before self-admin0.91.05.0-1.1-0.00.6-0.2-0.1-0.80.7-0.8-0.6-0.6-0.61.9-1.9-0.8-0.7-0.5-0.4-0.30.1-0.11.5-2.21.5
Time to tail flick, vehicle, after self-admin0.40.53.80.10.51.0-0.80.60.10.0-0.3-0.2-0.2-0.2-0.10.10.1-0.1-0.1-0.00.4-0.10.21.5-1.72.0
Time to tail flick, test, before self-admin0.40.42.2-0.6-0.5-0.80.6-0.5-0.60.1-0.10.10.10.11.3-1.3-0.1-0.20.1-0.0-0.30.3-0.1-0.90.5-1.5
Time to tail flick, test, after self-admin0.00.00.20.00.30.2-0.50.0-0.30.0-0.10.10.10.1-0.00.00.00.3-0.10.50.10.40.00.1-0.20.2
Delta time to tail flick, vehicle, before/after SA1.11.01.81.11.00.7-0.91.01.2-1.21.21.01.01.0-0.30.31.31.21.11.01.31.01.30.21.0-0.2
Delta time to tail flick, test, before/after SA0.30.32.1-0.00.40.9-0.70.3-0.10.1-0.0-0.1-0.1-0.1-0.00.0-0.2-0.0-0.20.00.20.00.01.1-1.31.5
Tibia length0.51.35.10.20.31.0-0.30.1-0.70.9-0.9-0.9-0.9-0.9-2.02.0-0.7-0.6-1.0-0.7-0.7-1.1-0.81.4-2.12.3
Ambulatory time before self-admin0.30.53.5-0.6-0.40.20.2-0.3-0.60.6-0.7-0.5-0.5-0.50.5-0.5-0.9-0.9-0.1-0.9-0.6-0.6-0.60.9-1.90.8
Ambulatory time after self-admin0.10.11.30.2-0.00.3-0.10.00.10.10.20.00.00.0-0.40.4-0.3-0.10.40.1-0.2-0.1-0.40.6-1.10.3
Bone: tissue strength1.61.63.1-0.8-0.9-0.30.8-1.0-1.21.5-1.3-1.5-1.5-1.5-0.70.7-1.3-1.5-1.5-1.5-1.4-1.4-1.70.2-1.81.7
Total heroin consumption0.70.83.10.81.01.2-1.10.90.4-1.00.61.31.31.3-0.30.30.30.21.20.10.50.70.31.8-1.30.0
Bone: trabecular number1.01.64.31.51.62.1-1.71.41.1-1.10.80.90.90.9-1.01.00.91.00.91.11.30.91.32.0-1.11.4
Bone: trabecular spacing0.20.31.2-0.6-0.5-0.80.5-0.3-0.10.10.20.00.00.01.0-1.0-0.2-0.20.2-0.2-0.30.0-0.3-0.60.7-1.1
Bone: trabecular thickness0.81.02.11.31.41.5-1.31.11.2-0.70.50.50.50.5-1.11.11.01.10.81.21.10.81.31.1-0.20.9
Bone: trabecular tissue density1.82.79.3-0.7-0.8-0.30.7-1.0-1.41.9-1.9-2.1-2.1-2.1-1.61.6-1.3-1.2-2.0-1.3-1.6-2.0-1.70.4-1.63.1
Water consumed over 24 hours0.10.11.30.40.10.10.00.10.1-0.20.00.10.10.1-1.11.10.20.1-0.10.20.1-0.10.1-0.1-0.1-0.0
Number of responses in last shaping day0.10.11.10.50.1-0.10.00.00.1-0.2-0.10.10.10.1-1.01.00.10.30.10.2-0.0-0.0-0.0-0.20.4-0.2