Hub : Genes

Tex2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Tex2 0.21 0.08 0.0e+00 0.23 0.25 0.24 0.23 2.7e-18 4.3e-20 1.8e-19 3.7e-18
2 NAcc gene expression Tex2 0.44 0.11 0.0e+00 0.32 0.39 0.39 0.39 1.6e-49 2.5e-62 1.1e-63 1.1e-63
3 Brain isoform ratio XM_006247647.4 0.05 0.02 3.0e-05 0.04 0.05 0.05 0.05 2.0e-04 3.3e-05 2.1e-05 2.2e-05
4 Brain isoform ratio NM_001100554.1 0.05 0.02 3.6e-05 0.04 0.05 0.05 0.05 1.0e-04 2.9e-05 2.7e-05 3.3e-05
5 Brain gene expression Tex2 0.23 0.07 0.0e+00 0.21 0.23 0.22 0.23 1.9e-19 6.2e-21 9.2e-21 4.6e-21
6 IL gene expression Tex2 0.21 0.1 3.1e-04 0.16 0.15 0.12 0.16 1.1e-04 1.7e-04 8.8e-04 1.5e-04
7 Liver intron excision ratio chr10_91998797_92017411 0.41 0.09 0.0e+00 0.42 0.43 0.44 0.45 3.1e-51 2.8e-51 3.7e-53 9.3e-55
8 BLA gene expression Tex2 0.35 0.1 0.0e+00 0.36 0.35 0.36 0.36 4.0e-20 3.3e-19 3.5e-20 2.5e-20
9 Liver alternative TSS XM_006247647.4 0.11 0.05 1.8e-08 0.07 0.05 0.05 0.06 2.1e-08 3.0e-06 7.0e-06 2.5e-07
10 Liver isoform ratio NM_001100554.1 0.11 0.05 5.7e-10 0.1 0.08 0.08 0.09 8.6e-11 1.6e-09 1.6e-09 1.5e-10
11 Liver intron excision ratio chr10_91998797_92045841 0.21 0.07 0.0e+00 0.18 0.17 0.17 0.17 2.4e-19 3.6e-18 4.0e-18 2.8e-18
12 LHb isoform ratio NM_001100554.1 0.31 0.14 2.6e-03 0.15 0.09 0.09 0.13 1.9e-04 4.3e-03 4.6e-03 5.7e-04
13 LHb isoform ratio XM_006247647.4 0.31 0.15 6.8e-03 0.14 0 0.04 0.09 3.1e-04 2.3e-01 3.7e-02 3.5e-03
14 LHb gene expression Tex2 0.3 0.13 1.4e-04 0.15 0.09 0.05 0.14 2.5e-04 3.5e-03 2.0e-02 3.6e-04
15 IC isoform ratio XM_006247647.4 0.07 0.04 6.2e-03 0.04 0.02 0.01 0.02 1.0e-02 3.3e-02 1.2e-01 4.5e-02
16 Liver alternative TSS XM_006247647.4 0.07 0.04 1.8e-06 0.05 0.04 0.04 0.05 1.6e-06 6.2e-05 1.2e-05 4.5e-06
17 pVTA isoform ratio XM_006247647.4 0.04 0.03 7.9e-03 0.03 0.01 0.02 0.02 1.1e-03 2.3e-02 7.1e-03 1.2e-02
18 PL gene expression Tex2 0.29 0.09 0.0e+00 0.34 0.34 0.35 0.35 9.3e-39 7.5e-39 1.3e-39 1.3e-39
19 IC gene expression Tex2 0.23 0.09 3.6e-11 0.2 0.22 0.23 0.19 9.4e-09 1.1e-09 6.8e-10 2.9e-08
20 Liver gene expression Tex2 0.11 0.04 3.1e-10 0.11 0.08 0.08 0.09 5.3e-12 3.0e-09 2.4e-09 6.2e-10
21 OFC gene expression Tex2 0.52 0.14 3.7e-08 0.15 0.23 0.23 0.23 2.0e-04 2.8e-06 3.0e-06 4.4e-06
22 Brain mRNA stability Tex2 0.07 0.05 3.4e-03 0.03 0.02 0.03 0.03 7.4e-04 5.8e-03 2.0e-03 1.7e-03
23 Adipose gene expression Tex2 0.25 0.07 2.5e-14 0.12 0.13 0.12 0.13 2.2e-13 2.7e-14 6.4e-13 4.4e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.30.51.50.8-1.2-1.01.00.8-0.4-0.50.2-0.4-0.4-0.40.8-0.8-0.4-0.4-0.3-0.5-0.7-0.3-1.10.80.90.8
Area under the delay curve0.20.32.50.4-0.8-0.50.70.5-0.3-0.0-0.20.00.00.00.8-0.8-0.3-0.10.1-0.3-0.30.1-0.8-0.10.61.6
BMI with tail1.24.117.42.9-0.6-1.51.31.7-2.3-1.81.7-1.5-1.5-1.54.2-4.2-2.4-1.8-1.5-1.7-1.4-0.50.51.0-2.9-0.3
BMI without tail1.58.027.54.1-1.6-2.62.32.5-3.1-2.52.5-2.3-2.3-2.35.2-5.2-3.3-3.0-2.1-3.0-2.2-1.2-0.11.7-3.30.4
Body weight2.912.722.84.8-3.5-4.13.83.8-3.9-3.53.5-3.2-3.2-3.24.7-4.7-4.1-4.0-3.1-3.9-3.5-2.6-2.12.9-2.30.8
Weight adjusted by age0.10.41.0-0.60.30.5-0.1-0.50.50.8-0.70.80.80.80.0-0.00.70.60.60.80.50.7-0.1-0.90.81.0
Bone surface2.85.514.22.5-3.8-3.13.02.6-2.1-2.22.1-2.2-2.2-2.20.6-0.6-1.9-2.1-1.9-2.0-2.5-2.3-3.42.41.71.7
Bone volume2.14.110.22.3-3.2-2.72.72.3-1.8-1.91.7-1.8-1.8-1.81.2-1.2-1.7-1.9-1.5-1.9-2.2-1.8-2.92.11.41.6
Breakpoint value in progressive ratio session0.20.31.50.40.0-0.10.10.1-0.3-0.70.4-0.9-0.9-0.9-0.10.1-0.10.1-1.00.0-0.2-0.5-0.10.1-0.1-1.2
Number of licking bursts0.00.11.8-0.2-0.4-0.10.30.1-0.20.00.00.00.00.0-0.30.30.20.1-0.10.0-0.0-0.0-0.7-0.21.40.5
Context. condit. distance diff. score0.00.00.10.10.30.1-0.10.0-0.1-0.20.3-0.1-0.1-0.10.3-0.30.1-0.1-0.4-0.00.10.40.1-0.2-0.3-0.1
Locomotion velocity, session 10.50.61.41.0-1.2-1.10.80.9-0.4-0.80.4-0.7-0.7-0.70.8-0.8-0.7-0.6-0.4-0.6-0.7-0.8-1.10.70.30.6
Locomotion distance, session 10.30.42.50.6-0.6-0.50.40.0-0.20.2-0.20.40.40.41.6-1.6-0.0-0.10.3-0.30.10.2-0.6-0.30.11.6
Locomotion velocity, session 20.50.61.30.8-0.6-0.70.50.6-0.3-0.90.9-1.2-1.2-1.2-0.10.1-0.6-0.4-0.8-0.6-0.5-1.1-0.90.6-0.0-0.9
Locomotion distance, session 20.10.20.60.4-0.5-0.30.20.10.0-0.00.1-0.1-0.1-0.10.8-0.80.00.2-0.10.50.20.1-0.7-0.50.60.7
Locomotion velocity, session 30.50.62.3-0.00.40.6-0.5-0.50.40.6-0.60.60.60.61.5-1.50.90.70.20.70.81.0-0.1-1.10.80.2
Locomotion distance, session 30.10.21.20.1-0.5-0.20.30.1-0.00.20.00.10.10.10.4-0.40.40.2-0.30.40.20.1-0.8-0.31.10.5
Stereotopy head waving bouts, day 30.50.61.7-0.60.70.9-0.8-0.61.00.7-1.10.80.80.80.4-0.40.70.81.30.60.61.00.5-0.70.20.2
Stereotopy head waving duration, day 30.40.41.1-0.50.40.8-0.6-0.30.80.5-0.90.70.70.70.5-0.50.60.71.10.40.40.9-0.0-0.90.60.7
Locomotion velocity, session 70.40.50.9-0.70.90.9-1.0-0.80.50.6-0.60.60.60.6-0.30.30.70.80.40.90.80.70.8-0.5-0.3-0.4
Locomotion distance, session 70.00.10.50.10.10.10.0-0.0-0.30.10.00.10.10.1-0.10.1-0.2-0.1-0.2-0.20.10.00.2-0.3-0.50.7
Stereotopy head waving bouts, day 70.60.72.0-0.80.50.8-0.8-0.71.40.7-1.10.60.60.60.1-0.11.10.91.01.01.00.9-0.0-1.11.1-0.2
Stereotopy head waving duration, day 71.41.74.2-1.61.01.4-1.3-1.22.11.1-1.50.90.90.9-0.70.71.61.61.41.71.41.20.1-1.51.7-0.6
Locomotion velocity, session 80.50.61.20.5-0.7-0.80.70.9-0.3-1.11.0-1.1-1.1-1.1-0.40.4-0.6-0.5-0.9-0.2-0.9-0.9-1.00.90.3-0.5
Locomotion distance, session 80.10.20.70.5-0.4-0.40.30.5-0.5-0.60.7-0.5-0.5-0.50.6-0.6-0.3-0.3-0.9-0.0-0.3-0.1-0.6-0.0-0.00.2
Degree of sensitization distance0.30.30.90.4-0.3-0.40.40.5-0.6-0.40.5-0.3-0.3-0.3-0.40.4-1.0-0.8-0.1-0.9-0.6-0.50.00.4-0.90.8
Degree of sensitization stereotypy0.80.92.1-0.80.91.0-1.1-1.11.50.9-1.00.70.70.70.3-0.31.31.10.81.21.41.00.4-1.40.8-0.7
Conditioned locomotion0.60.71.30.9-0.6-0.70.70.8-1.1-0.91.0-0.9-0.9-0.90.1-0.1-1.1-1.1-1.0-0.8-0.9-0.8-0.20.7-0.9-0.1
Cocaine response after cond. corrected0.50.82.3-1.0-0.20.4-0.3-0.40.70.8-1.00.80.80.8-1.31.30.70.90.71.10.50.6-0.7-0.61.51.5
Cocaine response after cond. not corrected0.91.34.9-1.4-0.20.6-0.6-0.71.00.9-1.20.90.90.9-1.81.81.21.40.61.40.80.6-0.9-0.82.20.9
Cocaine response before conditioning0.10.21.0-0.20.10.2-0.2-0.30.30.3-0.30.10.10.10.1-0.10.60.5-0.10.30.60.2-0.2-0.41.0-0.8
Saline control response2.33.16.82.0-0.5-1.31.21.5-1.9-2.02.1-2.1-2.1-2.11.2-1.2-2.0-2.1-2.0-1.9-1.6-1.70.21.4-2.6-2.0
Bone: connectivity density0.81.33.41.3-1.9-1.51.51.3-1.0-1.00.9-1.0-1.0-1.00.5-0.5-0.9-0.9-0.9-1.0-1.2-0.9-1.71.20.81.0
Bone: cortical apparent density3.35.29.1-1.82.52.5-2.4-2.41.92.6-2.62.92.92.91.5-1.52.42.32.22.22.53.01.9-2.50.30.7
Bone: cortical area1.01.612.11.7-1.2-1.00.90.9-0.8-0.50.4-0.3-0.3-0.33.5-3.5-0.4-0.4-0.4-0.3-0.40.2-1.00.10.61.1
Bone: cortical porosity3.64.07.02.2-2.2-2.31.92.0-1.6-2.52.0-2.6-2.6-2.6-0.10.1-1.8-1.6-2.3-1.4-2.0-2.6-1.92.10.1-1.6
Bone: cortical porosity2.83.04.92.2-2.2-2.11.92.0-1.4-2.01.6-2.1-2.1-2.11.2-1.2-1.6-1.5-1.9-1.3-1.7-1.9-1.91.60.5-0.7
Bone: cortical thickness7.312.220.8-1.93.33.4-3.4-3.43.13.7-3.94.04.04.04.1-4.13.53.63.73.73.94.62.7-4.00.70.7
Bone: cortical thickness4.45.47.9-1.42.72.4-2.5-2.62.32.5-2.42.52.52.52.1-2.12.52.32.42.42.82.82.4-2.6-0.0-0.3
Bone: cortical tissue density3.25.08.4-1.82.52.5-2.4-2.41.92.6-2.52.82.82.81.3-1.32.42.32.22.22.52.92.0-2.40.10.5
Condit. Reinf. active minus inactive responses2.52.84.32.1-1.6-1.91.91.7-1.7-2.11.8-2.0-2.0-2.00.8-0.8-1.8-2.0-1.9-1.7-1.8-1.8-1.01.4-0.7-0.6
Condit. Reinf. active-inactive response ratio1.11.12.01.1-0.9-1.21.21.1-1.0-1.41.2-1.3-1.3-1.3-0.20.2-1.1-1.3-1.2-1.1-1.2-1.2-0.61.0-0.3-0.5
Condit. Reinf. active responses3.34.36.22.5-2.1-2.32.32.3-2.3-2.42.3-2.4-2.4-2.41.1-1.1-2.3-2.4-2.2-2.0-2.3-2.1-1.51.8-0.7-0.3
Condit. Reinf. inactive responses1.21.52.71.5-1.7-1.51.51.5-1.6-1.21.2-1.1-1.1-1.11.2-1.2-1.3-1.2-1.1-0.9-1.4-0.9-1.40.90.20.9
Incentive salience index mean2.02.63.91.9-1.7-1.91.81.7-1.5-1.91.7-2.0-2.0-2.00.7-0.7-1.6-1.8-1.8-1.5-1.7-1.8-1.21.4-0.4-0.9
Condit. Reinf. lever presses0.40.62.00.7-0.8-0.90.60.7-0.4-0.80.7-1.0-1.0-1.00.3-0.3-0.6-0.7-0.7-0.5-0.7-1.0-0.50.6-0.3-1.4
Condit. Reinf. active minus inactive responses4.36.713.73.2-3.7-3.23.23.0-2.3-2.62.4-2.7-2.7-2.72.0-2.0-2.4-2.5-2.5-2.1-2.5-2.3-3.61.71.31.3
Condit. Reinf. active-inactive response ratio1.82.96.11.8-2.5-2.22.12.0-1.4-1.91.5-1.9-1.9-1.90.3-0.3-1.6-1.7-1.7-1.3-1.8-1.9-2.31.50.90.2
Condit. Reinf. active responses6.39.014.73.8-3.6-3.53.53.4-3.1-3.13.1-3.3-3.3-3.32.4-2.4-3.1-3.2-3.1-3.0-3.0-2.8-3.22.30.20.9
Condit. Reinf. inactive responses2.43.67.42.7-1.5-1.81.91.9-2.3-1.82.1-1.9-1.9-1.92.6-2.6-2.1-2.0-1.9-2.1-1.6-1.4-0.91.2-1.10.4
Condit. Reinf. lever presses1.92.75.22.3-1.6-1.81.61.6-1.5-1.81.8-1.9-1.9-1.91.9-1.9-1.6-1.6-1.8-1.6-1.4-1.5-1.01.1-0.6-0.6
Condit. Reinf. lever reinforcers received5.47.612.43.5-3.3-3.23.23.1-2.9-2.92.9-3.0-3.0-3.02.1-2.1-2.9-2.9-2.9-2.7-2.7-2.6-2.92.20.10.8
Conditioned reinforcement - actives0.21.02.01.3-0.9-1.11.11.0-1.4-1.11.0-0.9-0.9-0.91.3-1.3-1.0-0.9-1.1-1.1-0.9-0.6-0.50.6-0.50.1
Conditioned reinforcement - inactives0.41.02.01.4-0.6-1.10.90.8-1.4-1.11.2-0.9-0.9-0.91.1-1.1-1.0-1.1-1.2-1.2-0.8-0.7-0.11.0-1.0-0.3
Conditioned locomotion2.43.66.22.4-1.7-2.22.21.8-2.5-2.12.0-1.8-1.8-1.81.6-1.6-2.0-2.2-2.3-2.3-1.9-1.8-1.01.9-1.1-0.3
Patch foraging indifference point 0 sec2.26.311.63.4-2.7-2.92.82.7-3.0-2.42.6-2.2-2.2-2.23.0-3.0-2.8-2.8-2.6-2.6-2.4-1.9-2.01.8-0.91.3
Patch foraging indifference point AUC0.61.42.51.4-1.2-1.31.31.3-1.2-1.11.3-1.1-1.1-1.11.5-1.5-1.1-1.4-1.2-1.6-1.2-0.8-1.11.0-0.00.3
Delay disc. indifference point, 0s delay0.30.31.1-0.80.10.4-0.1-0.40.30.7-0.70.70.70.7-0.60.60.70.40.70.20.30.4-0.0-0.60.81.1
Delay disc. indifference point, 16s delay0.40.61.71.0-0.9-0.71.01.0-0.8-0.60.2-0.5-0.5-0.51.2-1.2-0.9-0.2-0.3-0.4-0.8-0.1-0.90.30.11.3
Delay disc. indifference point, 2s delay1.01.27.10.5-2.0-1.31.51.0-0.6-0.30.3-0.2-0.2-0.20.3-0.3-0.4-0.7-0.1-0.7-0.9-0.4-2.00.41.82.7
Delay disc. indifference point, 24s delay1.11.85.11.9-1.5-1.41.41.5-1.3-1.21.0-1.0-1.0-1.02.3-2.3-1.6-1.1-0.8-1.3-1.3-0.6-1.10.9-0.51.3
Delay disc. indifference point, 4s delay0.60.61.3-0.90.20.5-0.4-0.70.81.0-1.11.01.01.0-0.40.41.00.80.80.60.90.7-0.0-0.91.10.8
Delay disc. indifference point, 8s delay0.10.21.7-0.1-0.2-0.00.1-0.10.10.4-0.70.50.50.50.6-0.60.10.20.60.10.10.4-0.2-0.40.41.3
Indifference point function ln k0.20.71.6-0.40.50.9-0.9-0.60.80.8-1.10.90.90.90.8-0.80.71.10.81.21.01.10.2-1.30.40.5
Indifference point function log k0.20.71.6-0.40.50.9-0.9-0.60.80.8-1.10.90.90.90.8-0.80.71.10.81.21.01.10.2-1.30.40.5
Patch foraging total patch changes 0 sec2.26.611.93.5-2.8-3.02.92.8-3.1-2.52.7-2.3-2.3-2.32.9-2.9-2.9-2.9-2.7-2.6-2.5-2.0-2.11.9-0.81.3
Patch foraging total patch changes 12 sec5.77.712.13.1-3.0-3.43.53.0-2.9-2.83.2-2.8-2.8-2.81.5-1.5-3.0-3.5-2.6-3.5-3.0-2.9-2.42.6-0.70.8
Patch foraging total patch changes 18 sec1.74.16.92.6-1.8-2.22.12.1-2.2-2.12.2-2.1-2.1-2.12.0-2.0-2.3-2.5-2.1-2.5-1.9-1.9-1.31.6-1.10.1
Patch foraging total patch changes 24 sec1.55.09.53.0-2.5-2.62.62.4-2.3-2.02.0-1.9-1.9-1.93.1-3.1-2.2-2.3-2.2-2.4-2.0-1.5-2.01.6-0.01.4
Patch foraging total patch changes 6 sec2.13.66.72.6-2.0-2.22.12.0-2.1-1.82.0-1.7-1.7-1.72.3-2.3-1.9-2.1-2.1-2.0-1.8-1.4-1.41.6-0.70.6
Patch foraging time to switch 0 sec0.20.93.7-1.21.20.8-0.8-1.01.20.6-0.70.50.50.5-1.91.90.70.61.00.70.6-0.01.1-0.3-0.6-1.2
Patch foraging water rate 0 sec0.72.65.72.3-1.6-1.71.51.7-2.1-1.61.7-1.4-1.4-1.42.4-2.4-1.8-1.7-1.5-1.7-1.5-0.9-0.91.3-0.70.8
Patch foraging water rate 12 sec0.52.03.9-0.80.91.3-1.3-1.31.31.6-1.61.61.61.61.3-1.31.51.51.51.51.72.00.5-1.71.11.3
Patch foraging water rate 18 sec0.30.73.50.2-0.40.2-0.2-0.00.30.5-0.60.60.60.61.4-1.40.50.90.41.00.61.0-0.9-0.91.91.4
Patch foraging water rate 24 sec0.20.32.2-0.2-0.50.00.1-0.00.10.4-0.30.40.40.40.1-0.10.30.50.30.60.40.4-0.8-0.61.51.3
Patch foraging water rate 6 sec0.30.42.00.3-0.10.0-0.1-0.1-0.20.4-0.60.60.60.61.4-1.40.30.60.20.50.40.7-0.2-0.60.91.1
Seeking ratio, delayed vs. immediate footshock0.20.21.50.30.50.2-0.30.00.0-0.20.1-0.2-0.2-0.20.8-0.8-0.5-0.20.2-0.2-0.1-0.01.10.0-1.2-0.8
Distance traveled before self-admin0.40.93.9-0.90.00.7-0.4-0.60.80.9-1.00.80.80.8-0.50.51.21.10.41.10.90.8-0.7-1.12.00.9
Distance traveled after self-admin0.20.33.4-0.1-0.60.10.10.0-0.00.20.10.10.10.1-0.20.20.50.4-0.40.20.30.2-1.0-0.51.80.6
Extensor digitorum longus weight1.04.118.4-2.23.72.6-2.3-2.01.31.4-1.41.61.61.6-1.11.10.80.92.21.01.01.44.3-0.9-3.5-1.6
Bone: elastic displacement2.32.94.5-1.41.61.8-1.8-1.72.11.8-2.01.91.91.90.8-0.82.02.01.92.11.92.11.2-1.80.8-0.3
Bone: elastic work0.50.73.20.10.70.5-0.7-0.60.60.6-0.70.80.80.81.8-1.80.60.70.60.80.60.81.0-0.4-0.0-0.5
Bone: endosteal estimation11.929.040.85.4-6.4-6.26.05.9-5.8-6.06.1-6.1-6.1-6.1-0.60.6-5.6-5.7-6.0-5.7-5.9-6.3-5.15.9-0.30.2
Bone: endosteal perimeter12.731.149.65.7-7.0-6.66.56.5-5.7-6.16.1-6.1-6.1-6.10.4-0.4-5.8-5.9-5.9-5.8-6.2-6.0-6.05.90.41.2
Epididymis fat weight0.21.22.51.4-1.0-1.11.11.2-1.4-1.11.1-1.1-1.1-1.11.1-1.1-1.6-1.2-0.9-1.4-1.2-0.9-0.41.0-1.00.4
Delta time in closed arm before/after self-admin0.30.31.0-0.80.20.3-0.5-0.70.60.6-0.50.40.40.4-1.01.00.70.10.60.20.50.10.3-0.00.50.0
Delta time in open arm before/after self-admin0.10.20.60.30.30.20.10.3-0.7-0.40.4-0.1-0.1-0.10.4-0.4-0.5-0.5-0.6-0.6-0.40.10.2-0.0-0.8-0.1
Diff in mean of infusions in LGA sessions1.12.04.6-1.42.11.9-1.9-1.71.61.2-1.31.11.11.1-0.10.11.41.51.31.61.51.41.9-1.4-0.8-1.1
Delay discount exponential model param0.30.42.5-0.51.00.7-0.9-0.60.50.20.00.10.10.1-0.70.70.40.30.00.40.50.11.0-0.1-0.6-1.6
Extinction: sum of active levers before priming0.10.20.70.4-0.2-0.30.40.3-0.8-0.40.5-0.4-0.4-0.40.5-0.5-0.2-0.3-0.7-0.4-0.3-0.1-0.3-0.1-0.10.1
Active lever presses in extinction session 61.51.52.41.5-1.0-1.41.21.1-1.3-1.41.3-1.5-1.5-1.50.8-0.8-1.2-1.2-1.5-1.5-1.2-1.3-0.51.1-0.9-0.7
Bone: final force0.50.93.60.9-1.4-0.80.90.6-0.40.00.10.10.10.11.9-1.90.10.1-0.20.1-0.10.2-1.3-0.01.61.8
Bone: final moment0.50.83.60.9-1.3-0.70.70.5-0.40.10.00.10.10.11.9-1.90.20.2-0.20.2-0.00.3-1.2-0.01.61.6
Food consumed during 24 hour testing period1.93.76.12.2-1.6-2.01.72.1-2.5-2.32.1-2.2-2.2-2.21.7-1.7-2.4-2.1-1.9-2.1-2.1-1.7-0.81.8-1.5-0.4
Glucose1.01.52.9-1.30.91.3-1.2-1.11.71.4-1.41.31.31.30.0-0.01.51.51.31.51.51.40.0-1.60.80.4
Heart weight0.60.94.0-0.3-0.20.3-0.2-0.50.40.9-1.11.11.11.11.3-1.30.70.70.90.80.71.3-0.3-1.21.12.0
Delay discount hyperbolic model param0.30.42.5-0.41.00.8-0.9-0.60.40.10.00.10.10.1-0.60.60.40.40.00.50.50.21.0-0.2-0.7-1.6
Intermittent access intake day 1-15 change0.10.42.0-0.50.40.1-0.4-0.3-0.1-0.20.4-0.3-0.3-0.3-1.41.4-0.0-0.0-0.2-0.0-0.1-0.40.60.5-1.1-1.3
Intermittent access intake escalation0.10.41.10.1-0.2-0.40.20.3-0.5-0.60.8-0.8-0.8-0.8-1.01.0-0.5-0.5-0.6-0.5-0.5-0.80.10.8-1.0-1.0
Intermittent access intake escalation 20.50.82.00.1-0.1-0.50.20.4-0.7-0.81.0-0.9-0.9-0.9-1.41.4-0.7-0.7-0.8-0.8-0.8-1.20.21.2-1.2-1.3
Intermitt. access day 1 inactive lever presses0.33.34.82.1-1.4-2.01.71.8-2.2-2.22.1-2.1-2.1-2.10.7-0.7-2.1-1.8-2.1-1.7-2.0-2.0-0.62.0-1.6-1.3
Intermitt. access day 15 inactive lever presses0.41.97.71.30.2-0.80.50.9-1.9-1.51.3-1.4-1.4-1.40.0-0.0-1.7-1.2-1.6-1.1-1.2-1.51.11.7-2.8-2.0
Intermitt. access escalation Index0.82.54.7-1.80.91.7-1.3-1.32.01.7-1.81.51.51.5-1.01.01.82.11.72.01.71.6-0.0-2.02.20.9
Intermittent access day 1 total infusions0.51.65.61.8-1.5-1.41.41.3-1.2-1.11.0-1.0-1.0-1.02.4-2.4-0.9-0.8-1.2-0.8-0.8-0.4-1.50.30.60.9
Intermittent access day 15 total infusions0.92.13.91.8-1.6-1.71.51.6-2.0-1.61.7-1.5-1.5-1.51.3-1.3-1.5-1.4-1.8-1.4-1.4-1.1-1.21.1-0.50.1
Intermittent access terminal intake (last 3 days)2.13.76.12.2-2.1-2.32.12.1-2.5-2.22.3-2.1-2.1-2.11.0-1.0-2.1-1.9-2.3-2.0-2.0-1.8-1.61.9-0.40.2
Intermittent access total infusions3.13.76.02.4-2.4-2.32.22.2-2.2-2.02.1-1.9-1.9-1.92.1-2.1-1.9-1.7-2.1-1.8-1.7-1.3-2.01.30.20.8
Intermittent access day 1 locomotion2.24.18.72.9-2.0-2.32.12.0-2.3-2.22.0-2.0-2.0-2.02.9-2.9-1.9-1.9-2.3-1.9-1.7-1.4-1.41.4-0.8-0.1
Intermittent access day 15 total locomotion1.66.39.73.1-2.7-3.12.82.7-2.7-2.72.8-2.6-2.6-2.62.4-2.4-2.7-2.6-2.7-2.7-2.4-2.2-1.92.2-0.8-0.1
Intermittent access total locomotion7.48.816.04.0-3.0-3.53.23.1-3.2-3.13.2-3.0-3.0-3.03.7-3.7-3.0-3.0-3.1-3.1-2.7-2.3-2.22.3-1.1-0.0
Intermittent access standard deviation0.20.81.70.9-0.4-0.90.60.6-1.2-1.01.2-1.0-1.0-1.00.4-0.4-0.9-1.0-1.1-1.0-0.9-0.90.21.2-1.3-1.0
Left kidney weight0.21.44.20.0-0.30.5-0.5-0.41.00.9-1.10.90.90.92.0-2.00.91.11.20.81.11.6-0.6-1.41.62.0
Right kidney weight0.21.34.50.2-1.00.1-0.20.10.70.7-0.90.60.60.62.1-2.10.50.90.80.70.71.4-1.3-1.02.02.1
Cocaine induced anxiety0.41.02.2-0.90.60.9-1.1-1.00.91.1-1.21.21.21.20.0-0.01.11.50.91.41.21.20.3-1.10.50.3
Post-drug Anxiety1.11.22.1-1.00.81.0-1.2-1.21.11.3-1.31.31.31.30.0-0.01.21.31.21.41.41.30.6-1.10.70.4
Baseline Anxiety0.10.20.8-0.20.70.3-0.4-0.50.30.4-0.40.40.40.40.3-0.30.3-0.20.5-0.00.50.30.9-0.2-0.4-0.2
Tail length1.58.013.13.6-3.1-3.53.22.9-2.8-2.92.9-2.9-2.9-2.92.4-2.4-3.0-3.5-2.7-3.5-2.8-2.8-2.02.8-1.20.1
Length with tail1.87.915.73.0-4.0-3.73.63.3-2.3-2.72.7-2.7-2.7-2.71.3-1.3-2.8-3.2-2.2-3.3-3.1-2.9-3.32.90.41.3
Length without tail0.10.72.50.4-1.6-1.11.11.1-0.5-0.60.7-0.5-0.5-0.5-0.30.3-0.6-0.9-0.3-0.9-1.2-1.0-1.51.00.60.8
Times rat made contact with spout0.60.71.20.8-1.0-0.90.80.9-0.8-1.00.9-1.1-1.1-1.10.0-0.0-1.0-0.8-0.7-0.8-1.0-1.0-0.71.00.1-0.3
Lifetime Intake3.44.27.72.8-2.3-2.42.22.3-2.3-2.12.2-2.0-2.0-2.02.7-2.7-2.1-1.9-2.2-2.0-1.8-1.3-1.91.3-0.10.7
Liver weight, left3.25.511.22.5-3.4-2.92.72.9-1.6-2.52.3-2.7-2.7-2.70.8-0.8-2.1-2.1-2.3-2.2-2.3-2.4-3.32.21.30.3
Liver weight, right1.22.13.5-0.70.91.2-1.3-1.21.71.7-1.71.61.61.61.5-1.51.41.51.71.21.91.90.6-1.70.61.1
Locomotor activity1.01.68.51.8-1.0-0.80.60.9-1.4-1.11.2-1.2-1.2-1.22.9-2.9-0.8-0.4-1.3-0.3-0.4-0.1-0.8-0.2-0.0-0.2
Locomotor testing distance0.92.27.92.3-0.9-1.10.81.1-1.9-1.61.5-1.7-1.7-1.72.8-2.8-1.3-1.0-1.8-0.8-0.7-0.6-0.40.3-1.0-0.9
Locomotor testing rearing0.62.37.31.7-0.1-0.90.40.8-1.8-1.71.9-2.0-2.0-2.00.7-0.7-1.4-1.1-2.2-1.2-0.8-1.40.61.0-2.3-2.7
Locomotion in novel chamber0.30.42.9-0.5-0.7-0.10.0-0.10.90.5-0.50.30.30.3-0.80.80.50.60.50.40.40.1-0.9-0.21.70.5
Locomotion in novel chamber post-restriction0.72.17.90.9-2.4-1.72.11.5-1.3-0.91.1-0.7-0.7-0.7-0.30.3-0.8-1.2-1.0-1.3-1.5-1.2-2.81.21.82.4
Fecal boli incidents, locomotor time 10.10.21.2-0.2-0.4-0.10.30.2-0.4-0.10.2-0.0-0.0-0.0-1.11.1-0.1-0.3-0.5-0.2-0.4-0.4-0.60.30.30.2
Change in fecal boli incidents, locomotor task0.10.10.6-0.20.50.2-0.1-0.10.20.3-0.40.20.20.20.3-0.3-0.3-0.10.7-0.10.10.10.70.0-0.80.5
Time >=10cm from walls, locomotor time 11.92.44.9-1.81.11.6-1.3-1.51.81.7-1.51.61.61.6-1.11.11.91.81.41.81.71.50.2-1.72.20.7
Bouts of movement, locomotor time 10.50.72.8-0.61.20.8-1.0-0.80.40.7-0.70.80.80.8-0.10.10.30.60.80.50.70.71.6-0.3-1.7-0.7
Total resting periods, locomotor time 10.60.72.7-0.71.20.9-1.0-0.80.60.8-0.80.90.90.9-0.30.30.30.50.90.50.70.71.6-0.2-1.6-0.5
Rest time, locomotor task time 10.20.42.5-0.90.50.6-0.5-0.30.30.2-0.50.30.30.3-1.61.60.10.30.30.2-0.0-0.20.50.2-0.3-0.2
Distance moved, locomotor task time 10.10.31.10.8-0.4-0.80.70.3-0.3-0.50.6-0.5-0.5-0.51.1-1.1-0.4-0.6-0.0-0.6-0.3-0.3-0.20.5-0.6-0.2
Vertical activity count, locomotor time 10.00.20.60.7-0.7-0.60.60.2-0.4-0.30.4-0.4-0.4-0.40.8-0.8-0.1-0.3-0.2-0.2-0.2-0.2-0.40.30.30.3
Time >=10cm from walls, locomotor time 20.20.62.4-1.00.70.6-0.7-0.80.60.4-0.50.30.30.3-1.51.50.80.80.10.80.70.10.3-0.20.6-0.9
Bouts of movement, locomotor time 20.20.62.4-0.41.40.9-0.7-0.70.40.6-0.60.70.70.70.3-0.30.30.20.60.20.50.61.6-0.5-1.5-0.6
Total resting periods, locomotor time 20.20.72.5-0.51.51.1-0.9-0.90.70.8-0.80.90.90.90.3-0.30.50.30.80.40.80.81.6-0.7-1.3-0.5
Rest time, locomotor task time 21.93.25.4-2.31.72.1-1.7-1.81.81.9-2.12.02.02.0-1.71.71.91.71.91.81.61.81.2-1.71.00.8
Distance moved, locomotor task time 20.30.42.90.50.0-0.70.20.1-0.1-0.50.7-0.7-0.7-0.70.1-0.1-0.4-0.5-0.3-0.6-0.2-0.90.40.8-1.2-1.7
Vertical activity count, locomotor time 20.92.03.61.7-0.7-1.40.91.0-1.4-1.71.6-1.8-1.8-1.80.8-0.8-1.2-1.4-1.6-1.5-1.2-1.6-0.01.6-1.5-1.9
Light reinforcement 10.21.18.81.4-0.3-0.50.60.7-1.1-0.50.2-0.3-0.3-0.33.0-3.0-0.8-0.6-0.6-0.7-0.50.40.1-0.3-0.70.8
Light reinforcement 20.30.84.51.1-0.6-0.70.80.7-1.0-0.60.2-0.5-0.5-0.52.1-2.1-0.7-0.8-0.4-0.7-0.80.1-0.30.2-0.31.0
Bone: marrow area11.327.839.15.2-6.3-6.15.85.8-5.7-5.86.0-6.0-6.0-6.0-0.80.8-5.5-5.6-5.9-5.5-5.8-6.2-5.05.8-0.30.2
Bone: maximum diameter3.36.514.23.0-3.8-3.13.13.1-2.5-2.52.4-2.5-2.5-2.51.6-1.6-2.4-2.4-2.3-2.3-2.7-2.3-3.52.31.21.6
Bone: maximum force1.12.18.21.9-2.1-1.61.71.3-1.0-0.50.6-0.4-0.4-0.42.9-2.9-0.8-0.7-0.4-0.8-0.8-0.3-1.80.31.32.7
Bone: maximum moment1.01.87.71.8-2.0-1.51.51.2-1.0-0.50.5-0.3-0.3-0.32.8-2.8-0.8-0.6-0.4-0.7-0.7-0.2-1.60.41.22.3
Mean time between licks in bursts0.00.31.40.3-0.8-0.60.70.5-0.8-0.20.4-0.1-0.1-0.10.2-0.2-0.4-0.4-0.4-0.4-0.6-0.3-0.60.40.51.2
Mean num. licks in bursts0.10.42.40.7-0.1-0.40.20.5-0.3-0.60.5-0.6-0.6-0.60.5-0.5-0.9-0.7-0.2-0.6-0.6-0.50.40.8-1.6-0.6
Cd content in liver2.83.110.6-2.52.22.1-2.0-1.71.71.3-1.41.31.31.3-3.33.31.41.51.51.41.11.01.9-0.6-0.7-1.0
Co content in liver0.81.02.3-1.31.31.4-1.2-0.91.50.5-0.80.60.60.6-0.90.91.11.11.20.90.60.90.8-0.60.3-1.2
Cu content in liver0.30.40.90.4-0.3-0.40.40.6-0.4-0.90.5-0.8-0.8-0.8-0.30.3-0.7-0.6-0.4-0.5-0.9-0.8-0.00.9-0.7-0.7
Fe content in liver0.10.11.00.2-0.4-0.10.30.10.5-0.10.2-0.2-0.2-0.20.4-0.40.40.0-0.40.00.0-0.3-0.8-0.31.0-0.3
K content in liver0.70.74.10.6-1.5-0.81.01.1-0.4-0.60.6-0.7-0.7-0.70.3-0.3-0.4-0.2-0.6-0.3-0.8-0.4-2.00.41.60.9
Mg content in liver0.20.20.6-0.80.30.6-0.4-0.10.60.3-0.40.30.30.3-0.60.60.50.70.50.30.10.4-0.2-0.20.7-0.1
Mn content in liver0.60.74.1-0.2-0.60.2-0.0-0.10.70.6-0.60.50.50.50.7-0.70.80.90.60.70.50.8-1.5-0.72.01.3
Na content in liver0.80.92.80.8-1.2-0.70.91.2-0.3-1.20.8-1.3-1.3-1.30.5-0.5-0.6-0.5-0.8-0.6-1.0-0.7-1.70.41.0-0.4
Rb content in liver3.23.87.5-2.31.52.2-2.0-1.82.72.1-2.12.02.02.0-0.70.72.32.42.52.22.02.00.4-2.11.70.3
Se content in liver0.91.02.7-0.40.10.8-0.3-0.31.30.8-1.10.90.90.91.2-1.20.90.91.11.00.71.4-0.7-1.51.61.4
Sr content in liver0.40.30.60.7-0.6-0.60.50.8-0.5-0.60.5-0.6-0.6-0.60.6-0.6-0.6-0.5-0.6-0.5-0.6-0.4-0.60.70.10.0
Zn content in liver0.40.51.1-0.80.20.6-0.6-0.31.10.6-0.90.60.60.6-0.30.30.60.91.00.80.60.7-0.3-0.71.00.8
Bone: minimum diameter10.119.530.25.1-5.5-5.45.25.1-4.9-4.74.7-4.6-4.6-4.62.0-2.0-4.6-4.7-4.7-4.6-4.9-4.4-4.44.5-0.21.0
Time in familiar zone, hab. session 11.01.11.80.7-0.9-1.01.11.1-1.0-1.11.3-1.2-1.2-1.2-0.90.9-1.3-1.2-1.0-0.8-1.3-1.3-0.61.2-0.80.0
Time in novel zone, hab. session 11.51.72.7-0.91.61.5-1.5-1.41.31.4-1.51.51.51.50.8-0.81.51.41.41.01.61.61.2-1.40.3-0.1
Total zone transitions, hab. session 10.30.43.00.8-0.5-0.50.30.3-0.4-0.20.3-0.1-0.1-0.11.7-1.7-0.4-0.2-0.2-0.1-0.10.2-0.3-0.2-0.20.7
Total locomotion distance, hab. session 10.60.85.91.4-0.8-0.90.60.5-0.6-0.40.4-0.3-0.3-0.32.4-2.4-0.6-0.5-0.3-0.8-0.2-0.1-0.30.2-0.40.7
Locomotion velocity, hab. session 10.81.14.31.5-1.3-1.41.10.9-1.0-0.70.8-0.6-0.6-0.62.1-2.1-0.9-0.8-0.7-1.1-0.6-0.6-0.80.5-0.30.8
Time in familiar zone, hab. session 21.61.83.21.2-1.2-1.41.31.4-1.2-1.71.8-1.8-1.8-1.8-0.50.5-1.5-1.5-1.6-1.2-1.5-1.5-0.81.4-0.5-0.7
Time in novel zone, hab. session 21.92.03.9-1.21.11.4-1.3-1.51.21.8-1.92.02.02.00.3-0.31.51.61.81.21.61.50.7-1.40.61.2
Total zone transitions, hab. session 20.20.21.30.6-0.4-0.40.30.3-0.4-0.40.5-0.3-0.3-0.31.1-1.1-0.3-0.2-0.4-0.0-0.2-0.0-0.4-0.1-0.20.1
Total locomotion distance, hab. session 20.50.73.01.2-0.6-0.90.70.6-0.9-0.60.8-0.4-0.4-0.41.7-1.7-0.8-0.8-0.5-0.9-0.6-0.3-0.20.4-1.10.5
Locomotion velocity, hab. session 20.50.62.71.1-0.8-0.90.80.7-0.8-0.50.7-0.3-0.3-0.31.7-1.7-0.8-0.7-0.4-0.9-0.6-0.3-0.40.4-0.90.8
Novel to familiar place preference ratio0.10.20.70.6-0.5-0.50.40.5-0.3-0.20.3-0.3-0.3-0.30.8-0.8-0.4-0.4-0.2-0.4-0.3-0.1-0.60.40.10.3
Novelty place preference0.10.10.50.4-0.3-0.20.20.3-0.0-0.10.1-0.2-0.2-0.20.7-0.7-0.2-0.20.0-0.2-0.00.0-0.40.20.10.2
Time in novel zone, NPP test0.10.10.50.3-0.2-0.10.00.20.10.0-0.0-0.1-0.1-0.10.7-0.70.0-0.00.2-0.00.20.2-0.40.00.20.2
Total zone transitions, NPP test0.60.86.00.8-0.8-0.50.40.3-0.20.10.00.20.20.22.4-2.4-0.1-0.00.10.00.10.6-0.9-0.70.61.6
Total locomotion distance, NPP test0.50.72.91.2-1.1-1.10.80.6-0.8-0.40.6-0.2-0.2-0.21.7-1.7-0.7-0.7-0.4-0.7-0.4-0.3-0.60.3-0.41.1
Locomotion velocity, NPP test0.60.95.01.2-0.9-1.00.80.6-1.0-0.30.5-0.1-0.1-0.12.2-2.2-0.8-0.8-0.3-0.8-0.5-0.1-0.40.1-0.71.3
Intraocular pressure0.71.14.51.5-0.3-0.70.60.6-1.4-0.80.6-0.5-0.5-0.51.9-1.9-1.4-1.2-1.0-1.0-0.7-0.40.40.3-2.10.3
Delta distance traveled before/after self-admin0.10.21.00.40.30.1-0.1-0.2-0.1-0.10.4-0.1-0.1-0.11.0-1.00.1-0.1-0.2-0.10.20.20.5-0.3-0.2-0.6
Delta ambulatory time before/after self-admin0.10.20.70.7-0.2-0.40.40.3-0.6-0.40.7-0.4-0.4-0.40.8-0.8-0.4-0.5-0.5-0.6-0.3-0.30.00.2-0.2-0.2
Parametrial fat weight0.20.63.3-0.5-1.0-0.50.30.5-0.3-0.3-0.2-0.3-0.3-0.3-1.81.8-0.20.20.00.3-0.6-0.4-1.01.00.91.0
Pavlov. Cond. lever latency1.21.63.6-1.71.41.4-1.2-1.30.91.3-1.11.41.41.4-1.91.91.01.01.30.91.00.91.1-0.7-0.01.0
Pavlov. Cond. magazine entry latency2.83.65.52.3-2.1-2.12.02.2-1.5-2.21.9-2.3-2.3-2.31.6-1.6-1.9-1.9-1.9-1.9-2.0-1.8-1.71.7-0.3-0.9
Pavlov. Cond. change in total contacts2.42.64.12.0-1.2-1.51.31.7-1.3-1.91.6-2.0-2.0-2.01.6-1.6-1.5-1.6-1.8-1.6-1.6-1.5-0.91.4-0.8-1.8
Pavlov. Cond. index score2.53.25.32.3-2.0-1.91.92.1-1.3-2.01.8-2.1-2.1-2.11.8-1.8-1.7-1.7-1.8-1.6-1.8-1.5-1.71.4-0.0-0.9
Pavlov. Cond. latency score2.12.74.72.2-1.8-1.81.71.9-1.2-1.91.6-2.0-2.0-2.01.9-1.9-1.5-1.5-1.6-1.5-1.6-1.3-1.61.20.1-0.9
Pavlov. Cond. lever contacts1.51.83.01.6-1.3-1.51.21.4-1.1-1.61.4-1.7-1.7-1.71.1-1.1-1.2-1.3-1.5-1.1-1.3-1.4-0.91.2-0.4-1.6
Pavlov. Cond. magazine entry number2.22.84.2-2.01.71.8-1.8-2.01.42.0-1.62.02.02.0-1.31.31.61.61.81.71.81.61.4-1.50.31.1
Pavlov. Cond. intertrial magazine entries1.72.14.21.9-1.4-1.51.71.5-1.9-1.31.4-1.1-1.1-1.12.0-2.0-1.7-1.7-1.4-1.4-1.5-0.9-0.90.6-0.51.3
Pavlov. Cond. lever-magazine prob. diff.2.42.95.02.2-2.0-1.91.82.0-1.2-1.91.6-2.0-2.0-2.01.9-1.9-1.6-1.6-1.6-1.6-1.7-1.5-1.71.40.0-0.8
Pavlov. Cond. response bias2.93.65.52.3-2.2-2.22.02.2-1.6-2.11.8-2.2-2.2-2.21.5-1.5-1.8-1.7-2.0-1.7-1.9-1.9-1.81.7-0.0-1.0
Pavlov. Cond. lever latency0.40.61.3-1.01.10.9-0.9-0.90.70.7-0.70.80.80.8-0.70.70.70.60.90.70.60.61.1-0.3-0.5-0.3
Pavlov. Cond. magazine entry latency1.62.33.6-1.90.91.5-1.3-1.41.71.7-1.51.61.61.6-1.11.11.91.91.21.81.71.50.2-1.71.80.6
Pavlov. Cond. change in total contacts0.51.22.41.0-1.4-1.21.31.4-0.9-1.21.3-1.4-1.4-1.4-0.00.0-1.1-0.9-1.3-1.1-1.1-1.2-1.60.70.5-0.1
Pavlov. Cond. index score0.10.11.20.1-0.6-0.20.30.30.1-0.10.1-0.2-0.2-0.2-0.10.10.10.2-0.40.10.1-0.1-0.9-0.31.10.2
Pavlov. Cond. latency score0.10.21.7-0.2-0.4-0.00.10.00.30.2-0.10.00.00.0-0.10.10.40.5-0.20.30.30.1-0.8-0.51.30.2
Pavlov. Cond. lever contacts0.30.51.00.9-0.9-0.80.80.8-0.6-0.60.6-0.7-0.7-0.71.0-1.0-0.6-0.6-0.8-0.6-0.5-0.4-0.80.20.30.2
Pavlov. Cond. magazine entry number2.63.45.52.2-1.2-1.81.71.8-2.0-2.11.9-2.0-2.0-2.01.2-1.2-2.3-2.3-1.5-2.3-2.2-1.9-0.32.2-2.0-0.5
Pavlov. Cond. intertrial magazine entries6.614.522.14.4-3.4-4.24.04.2-4.2-4.34.1-4.1-4.1-4.11.5-1.5-4.7-4.6-3.7-4.3-4.5-4.1-1.94.5-2.5-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.21.6-0.1-0.5-0.10.10.10.20.1-0.0-0.0-0.0-0.0-0.20.20.30.4-0.30.30.20.1-0.9-0.41.30.4
Pavlov. Cond. response bias0.10.20.80.4-0.7-0.40.50.4-0.2-0.10.2-0.2-0.2-0.20.5-0.5-0.1-0.0-0.4-0.1-0.1-0.1-0.9-0.20.90.6
Time in closed arm before self-admin0.20.31.70.20.60.4-0.5-0.60.50.1-0.20.20.20.21.3-1.30.50.60.10.40.60.60.8-0.6-0.2-0.8
Time in closed arm after self-admin0.70.81.8-1.10.70.8-1.0-1.21.30.9-0.80.80.80.8-0.70.71.21.11.01.11.00.70.7-0.60.9-0.3
Time in open arm before self-admin1.21.52.4-1.50.50.9-1.0-1.11.51.5-1.51.21.21.2-1.01.01.51.41.31.51.41.10.0-1.11.30.6
Time in open arm after self-admin0.20.20.60.4-0.4-0.50.60.8-0.7-0.40.4-0.4-0.4-0.4-0.00.0-0.7-0.6-0.6-0.6-0.6-0.4-0.60.3-0.40.4
Bone: periosteal estimation6.214.724.74.5-5.0-4.74.54.4-4.2-4.14.1-4.1-4.1-4.11.8-1.8-3.9-3.9-4.1-3.8-4.1-3.9-4.03.90.41.0
Bone: periosteal perimeter3.36.514.62.9-3.8-3.13.13.1-2.5-2.52.4-2.5-2.5-2.51.6-1.6-2.2-2.2-2.5-2.1-2.6-2.1-3.62.31.51.3
Bone: post-yield work0.91.63.61.4-1.9-1.71.51.4-1.3-1.31.4-1.3-1.3-1.30.1-0.1-1.2-1.2-1.2-1.4-1.3-1.5-1.41.20.40.8
Progressive ratio test 1 active lever presses2.03.58.02.6-2.0-2.11.91.9-2.4-1.91.8-1.6-1.6-1.62.8-2.8-1.8-1.7-2.1-1.8-1.6-1.0-1.51.1-0.40.6
Progressive ratio test 1 breakpoint2.34.08.32.8-2.1-2.22.12.1-2.5-2.02.0-1.8-1.8-1.82.9-2.9-2.0-1.9-2.2-2.0-1.7-1.2-1.61.2-0.60.6
Progressive ratio test 1 inactive lever presses1.64.38.42.9-2.1-2.42.22.2-2.5-2.22.2-2.0-2.0-2.02.6-2.6-2.1-1.9-2.4-1.9-1.8-1.4-1.71.4-0.30.4
Progressive ratio test 2 active lever presses4.25.910.23.0-3.0-3.02.82.8-3.2-2.62.5-2.3-2.3-2.32.0-2.0-2.6-2.4-2.8-2.4-2.5-2.0-2.42.0-0.10.9
Progressive ratio test 2 breakpoint5.06.410.73.1-3.1-3.12.92.9-3.3-2.72.6-2.5-2.5-2.51.9-1.9-2.7-2.5-3.0-2.5-2.6-2.1-2.52.2-0.10.9
Progressive ratio test 2 inactive lever presses1.13.66.92.6-1.8-2.21.92.0-2.4-2.01.9-1.7-1.7-1.72.5-2.5-2.2-1.9-1.9-1.9-1.8-1.2-1.11.4-1.00.6
Incentive Sensitization - Responses1.43.87.42.1-2.7-2.42.32.3-2.2-2.02.0-2.0-2.0-2.00.6-0.6-2.1-1.9-2.1-1.8-2.1-1.8-2.31.80.30.9
Incentive Sensitization - Breakpoint1.73.87.52.1-2.7-2.52.32.3-2.2-2.02.0-2.0-2.0-2.00.5-0.5-2.1-1.9-2.1-1.8-2.1-1.9-2.41.90.40.9
Sum of active levers in priming session hrs 5-60.30.31.0-0.40.91.0-0.8-0.60.10.2-0.30.10.10.10.1-0.10.50.7-0.10.60.50.70.7-1.0-0.3-0.6
Progressive ratio0.10.42.1-0.1-1.0-0.50.70.4-0.1-0.10.10.00.00.0-0.90.9-0.0-0.0-0.2-0.1-0.5-0.2-1.40.31.21.3
Food seeking constrained by brief footshock3.24.06.81.6-1.9-2.11.82.0-1.8-2.42.5-2.6-2.6-2.6-1.01.0-2.1-1.9-2.1-1.8-2.2-2.6-1.32.5-1.0-1.4
Seeking ratio, punishment vs. effort0.91.93.21.6-0.7-1.20.91.2-1.2-1.61.6-1.8-1.8-1.80.7-0.7-1.5-1.5-1.4-1.5-1.2-1.60.11.4-1.5-1.7
Retroperitoneal fat weight0.31.42.81.3-1.0-1.41.01.2-1.4-1.21.1-1.2-1.2-1.20.9-0.9-1.7-1.4-0.9-1.4-1.2-1.1-0.21.4-1.40.0
Reaction time number correct0.31.25.1-0.8-0.10.6-0.5-0.50.61.2-1.31.31.31.30.3-0.30.91.31.01.21.01.4-0.6-1.41.22.3
Reaction time mean minus median0.10.71.9-1.01.10.7-0.7-0.80.60.7-0.60.80.80.8-1.41.40.50.40.60.30.60.21.1-0.1-1.1-0.9
Reaction time mean minus median AUC0.21.52.4-1.41.21.3-1.0-1.21.41.5-1.41.51.51.5-0.50.51.41.31.61.21.31.20.6-1.20.30.4
Reaction time num false alarms2.44.17.62.5-2.8-2.52.42.2-1.9-2.02.0-2.2-2.2-2.21.8-1.8-1.8-2.1-2.1-1.9-1.9-1.7-2.31.40.80.8
Reaction time num false alarms AUC1.94.48.82.5-3.0-2.62.52.4-2.0-2.12.1-2.2-2.2-2.21.6-1.6-1.9-2.1-2.1-1.9-2.0-1.8-2.51.60.80.9
Reaction time trials correct on left0.31.25.1-0.8-0.10.6-0.5-0.50.61.2-1.31.31.31.30.3-0.30.91.31.01.21.01.4-0.6-1.41.22.3
Reaction time trials on left0.41.25.5-0.8-0.20.6-0.5-0.50.61.2-1.41.31.31.30.3-0.30.91.31.01.21.01.4-0.6-1.41.22.4
Reaction time mean0.61.32.3-1.41.31.2-1.1-1.41.21.3-1.01.21.21.2-1.51.51.31.11.01.11.20.70.8-0.90.4-0.3
Reaction time mean AUC0.71.83.0-1.71.61.6-1.4-1.61.41.4-1.21.31.31.3-1.71.71.41.31.11.31.40.81.2-1.00.2-0.7
Median of all reaction times0.81.32.0-1.31.21.3-1.1-1.41.21.2-1.11.11.11.1-1.31.31.31.21.01.31.20.80.7-1.00.7-0.2
Reaction time omissions0.10.21.4-0.00.3-0.20.1-0.20.00.2-0.20.30.30.3-0.70.7-0.2-0.20.2-0.4-0.1-0.40.60.5-1.20.4
Reaction time false alarm rate3.14.26.32.3-2.3-2.42.32.2-1.9-2.32.4-2.5-2.5-2.51.0-1.0-2.0-2.4-2.2-2.1-2.1-2.2-1.72.00.0-0.6
Reaction time premature initiation rate0.81.23.81.5-0.5-0.70.60.9-1.5-1.21.0-0.9-0.9-0.91.9-1.9-1.2-0.9-1.1-1.1-1.1-0.60.10.7-1.4-0.2
Reaction time premature initiations0.20.73.51.1-0.8-0.50.50.7-1.1-0.60.3-0.3-0.3-0.31.9-1.9-0.8-0.3-0.6-0.5-0.70.0-0.40.1-0.61.0
Std. dev. reaction times0.31.04.4-1.31.10.8-0.8-1.01.01.0-0.70.90.90.9-2.12.10.70.60.90.50.70.21.0-0.1-0.6-0.7
Reaction time trials completed0.41.25.5-0.8-0.20.6-0.5-0.50.61.2-1.41.31.31.30.3-0.30.91.31.01.21.01.4-0.6-1.41.22.4
Reaction time trials AUC0.31.25.4-0.8-0.10.6-0.5-0.50.61.2-1.31.31.31.30.2-0.20.91.31.01.21.01.4-0.5-1.31.12.3
Run reversals in cocaine runway, females1.01.25.2-0.91.71.2-1.4-1.20.60.8-1.00.80.80.8-0.60.60.40.71.10.70.70.82.3-0.2-1.9-1.1
Run reversals in cocaine runway, males0.10.20.3-0.50.20.2-0.2-0.40.40.5-0.50.50.50.5-0.60.60.50.20.50.10.30.2-0.1-0.20.50.3
Latency to leave start box in cocaine runway0.20.20.5-0.40.60.7-0.6-0.60.40.5-0.40.50.50.50.2-0.20.60.40.30.40.50.40.5-0.60.1-0.1
Latency to leave start box in cocaine runway, F0.60.81.7-0.50.80.9-0.8-1.01.01.0-1.01.01.01.00.8-0.81.10.90.90.81.10.80.5-1.30.50.0
Latency to leave start box in cocaine runway, M0.30.30.9-0.00.10.1-0.10.2-0.6-0.50.6-0.6-0.6-0.6-0.90.9-0.3-0.3-0.8-0.3-0.5-0.60.30.6-0.4-0.8
Std. dev. time between licks in bursts0.00.10.40.10.3-0.10.1-0.1-0.40.00.20.00.00.00.2-0.2-0.2-0.3-0.1-0.4-0.1-0.10.70.2-0.6-0.3
Total sessions with >9 infusions0.81.08.51.4-0.3-0.40.40.5-0.8-0.50.4-0.3-0.3-0.32.9-2.9-0.4-0.4-0.6-0.5-0.20.5-0.1-0.5-0.40.2
Short access day 1 total inactive lever presses0.91.96.02.1-1.2-1.61.21.3-1.2-1.41.2-1.1-1.1-1.12.4-2.4-1.5-1.4-1.0-1.5-1.0-0.9-0.61.0-0.70.1
Short access day 10 total inactive lever presses0.00.22.00.40.5-0.10.00.0-0.7-0.30.3-0.1-0.1-0.10.3-0.3-0.6-0.3-0.2-0.1-0.3-0.21.00.5-1.4-0.4
Short access day 1 total infusions0.81.613.51.8-0.5-0.50.60.8-0.8-0.70.5-0.5-0.5-0.53.7-3.7-0.7-0.6-0.5-0.7-0.30.5-0.4-0.60.10.5
Short access day 10 total infusions2.33.99.02.8-1.6-2.01.91.9-2.2-2.02.1-1.9-1.9-1.93.0-3.0-2.0-2.0-2.1-2.1-1.6-1.2-1.21.3-0.90.1
Short access total infusions1.52.28.62.2-1.2-1.31.21.4-1.5-1.41.4-1.3-1.3-1.32.9-2.9-1.3-1.2-1.5-1.3-1.0-0.5-0.90.5-0.30.2
Short access day 1 locomotion2.03.418.52.8-0.9-1.41.51.4-2.0-1.41.3-1.1-1.1-1.14.3-4.3-1.6-1.6-1.5-1.9-1.2-0.3-0.40.4-1.40.4
Short access day 10 total locomotion1.77.011.13.3-2.0-2.92.62.5-2.8-3.02.9-2.9-2.9-2.92.4-2.4-2.8-3.0-2.9-3.0-2.7-2.5-0.92.5-2.7-1.5
Short access total locomotion2.64.012.82.9-1.2-2.01.91.6-2.1-1.91.8-1.7-1.7-1.73.6-3.6-1.9-2.1-1.9-2.3-1.6-1.1-0.41.2-1.9-0.6
One hour access (0.3 mA shock)1.11.32.01.4-1.4-1.31.31.3-1.3-1.31.3-1.3-1.3-1.30.6-0.6-1.2-1.1-1.3-1.2-1.2-1.1-1.40.90.30.2
Compulsive drug intake0.91.32.8-1.40.30.9-0.9-0.91.51.3-1.41.11.11.1-1.11.11.21.41.41.31.20.9-0.2-1.11.70.9
One hour access (shock baseline)0.92.43.91.9-1.4-1.71.71.6-2.0-1.71.9-1.6-1.6-1.61.2-1.2-1.6-1.7-1.9-1.6-1.6-1.3-1.01.4-0.7-0.1
Social response proportion0.20.20.5-0.50.40.5-0.5-0.40.30.6-0.50.70.70.7-0.20.20.20.70.60.60.50.40.3-0.6-0.10.2
Social responses0.10.20.90.6-0.2-0.1-0.00.4-0.5-0.20.4-0.2-0.2-0.21.0-1.0-0.50.0-0.5-0.2-0.0-0.0-0.2-0.2-0.1-0.2
Social time0.20.32.9-0.40.10.3-0.3-0.0-0.2-0.1-0.1-0.2-0.2-0.2-1.71.7-0.10.4-0.20.3-0.2-0.4-0.10.3-0.3-0.5
Soleus weight0.10.42.50.9-0.6-0.40.60.8-0.1-0.50.2-0.5-0.5-0.51.6-1.6-0.3-0.2-0.3-0.1-0.40.0-0.7-0.00.30.1
Bone: stiffness0.91.56.61.2-2.1-1.41.61.2-0.7-0.50.7-0.5-0.5-0.51.5-1.5-0.6-0.4-0.4-0.5-0.6-0.3-2.20.12.02.6
Tibialis anterior weight0.41.48.40.80.9-0.10.20.6-0.7-1.20.9-1.0-1.0-1.01.1-1.1-1.3-1.2-0.4-1.0-1.2-0.61.61.0-2.9-1.9
Time to tail flick, vehicle, before self-admin0.81.05.0-1.1-0.70.00.2-0.10.80.7-0.80.60.60.6-1.91.90.80.70.50.40.3-0.1-1.5-0.22.21.5
Time to tail flick, vehicle, after self-admin0.20.53.80.1-1.0-0.50.80.6-0.10.0-0.30.20.20.20.1-0.1-0.10.10.10.0-0.40.1-1.5-0.11.72.0
Time to tail flick, test, before self-admin0.30.42.2-0.60.90.5-0.6-0.50.60.1-0.1-0.1-0.1-0.1-1.31.30.10.2-0.10.00.3-0.30.90.2-0.5-1.5
Time to tail flick, test, after self-admin0.00.00.20.0-0.2-0.30.50.00.30.0-0.1-0.1-0.1-0.10.0-0.0-0.0-0.30.1-0.5-0.1-0.4-0.10.00.20.2
Delta time to tail flick, vehicle, before/after SA0.91.01.81.1-0.7-1.00.91.0-1.2-1.21.2-1.0-1.0-1.00.3-0.3-1.3-1.2-1.1-1.0-1.3-1.0-0.21.2-1.0-0.2
Delta time to tail flick, test, before/after SA0.20.32.1-0.0-0.9-0.40.70.30.10.1-0.10.10.10.10.0-0.00.20.00.2-0.0-0.2-0.0-1.1-0.21.31.5
Tibia length0.51.35.10.2-1.1-0.30.30.10.70.9-0.90.90.90.92.0-2.00.70.61.00.70.71.1-1.4-1.12.12.3
Ambulatory time before self-admin0.20.53.5-0.6-0.30.4-0.2-0.30.60.6-0.70.50.50.5-0.50.50.90.90.10.90.60.6-0.9-0.81.90.8
Ambulatory time after self-admin0.10.11.30.2-0.40.00.10.0-0.10.10.2-0.0-0.0-0.00.4-0.40.30.1-0.4-0.10.20.1-0.6-0.31.10.3
Bone: tissue strength1.61.63.1-0.80.20.9-0.8-1.01.21.5-1.31.51.51.50.7-0.71.31.51.51.51.41.4-0.2-1.81.81.7
Total heroin consumption0.70.83.10.8-1.3-1.01.10.9-0.4-1.00.6-1.3-1.3-1.30.3-0.3-0.3-0.2-1.2-0.1-0.5-0.7-1.80.21.30.0
Bone: trabecular number0.81.64.51.5-2.1-1.61.71.4-1.1-1.10.8-0.9-0.9-0.91.0-1.0-0.9-1.0-0.9-1.1-1.3-0.9-2.01.11.11.4
Bone: trabecular spacing0.20.31.2-0.60.80.5-0.5-0.40.10.10.2-0.0-0.0-0.0-1.01.00.20.2-0.20.20.3-0.00.6-0.3-0.7-1.1
Bone: trabecular thickness0.71.02.11.3-1.5-1.41.31.1-1.2-0.70.5-0.5-0.5-0.51.1-1.1-1.0-1.1-0.8-1.2-1.1-0.8-1.11.20.20.9
Bone: trabecular tissue density1.62.79.3-0.70.20.8-0.7-1.01.41.9-1.92.12.12.11.6-1.61.31.22.01.31.62.0-0.4-1.91.63.1
Water consumed over 24 hours0.10.11.30.4-0.1-0.1-0.00.1-0.1-0.20.0-0.1-0.1-0.11.1-1.1-0.2-0.10.1-0.2-0.10.10.10.00.1-0.0
Number of responses in last shaping day0.10.11.10.50.1-0.1-0.00.0-0.1-0.2-0.1-0.1-0.1-0.11.0-1.0-0.1-0.3-0.1-0.20.00.00.2-0.1-0.4-0.2