Hub : Genes

Tcte1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye isoform ratio NM_001108206.1 0.7 0.17 9.6e-03 0.01 -0.02 -0.02 0.01 2.4e-01 9.2e-01 7.1e-01 2.1e-01
2 Brain isoform ratio NM_001108206.1 0.05 0.03 6.0e-04 0.03 0.02 0.03 0.01 2.0e-03 4.5e-03 1.6e-03 1.8e-02
3 PL gene expression Tcte1 0.16 0.09 1.5e-05 0.06 0.04 0.05 0.05 1.3e-07 5.2e-05 2.7e-06 2.8e-06
4 pVTA gene expression Tcte1 0.1 0.06 4.4e-03 0.06 0.05 0.03 0.05 2.0e-03 2.6e-03 1.3e-02 3.4e-03
5 Brain mRNA stability Tcte1 0.29 0.08 0.0e+00 0.31 0.33 0.33 0.33 2.0e-29 5.7e-31 3.4e-31 3.0e-31
6 BLA isoform ratio XM_006244539.4 0.07 0.04 2.4e-03 0.07 0.04 0.05 0.06 1.5e-04 3.6e-03 9.3e-04 5.5e-04
7 LHb gene expression Tcte1 0.23 0.13 3.5e-03 0.02 0.01 0.01 0.03 8.8e-02 1.7e-01 1.8e-01 7.2e-02
8 Brain isoform ratio XM_006244539.4 0.06 0.03 8.5e-05 0.03 0.03 0.01 0.02 3.4e-04 1.2e-03 2.4e-02 3.3e-03
9 LHb mRNA stability Tcte1 0.22 0.14 8.6e-03 0.05 0.03 0.04 0.02 2.2e-02 6.2e-02 3.5e-02 1.2e-01
10 PL isoform ratio XM_006244539.4 0.03 0.02 3.0e-03 0.03 0.01 0.01 0.01 1.2e-04 1.6e-02 7.4e-03 4.3e-02
11 BLA mRNA stability Tcte1 0.19 0.07 4.8e-10 0.19 0.17 0.18 0.19 1.5e-10 2.0e-09 8.9e-10 2.1e-10
12 BLA gene expression Tcte1 0.08 0.05 4.3e-03 0.06 0.05 0.06 0.06 2.5e-04 1.3e-03 6.6e-04 3.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.81.31.7-0.0-1.3-0.21.2-1.31.2-1.21.21.21.31.3-1.3
Area under the delay curve2.32.57.0-1.02.12.61.11.7-1.41.4-1.4-1.4-1.4-1.41.4
BMI with tail2.89.018.8-0.82.9-0.5-4.32.7-3.13.2-3.2-3.2-3.2-3.33.2
BMI without tail7.816.136.6-0.53.6-1.2-6.13.7-4.34.2-4.2-4.2-4.3-4.24.3
Body weight0.62.313.20.50.6-2.1-3.60.7-1.11.1-1.1-1.1-1.2-1.21.2
Weight adjusted by age0.10.20.6-0.7-0.00.80.60.1-0.10.2-0.2-0.2-0.3-0.30.4
Bone surface1.83.27.0-0.2-1.80.72.7-1.71.9-1.91.91.91.81.8-1.8
Bone volume1.32.34.6-0.3-1.50.42.1-1.51.6-1.61.61.61.61.6-1.6
Breakpoint value in progressive ratio session0.40.41.5-0.51.01.20.50.6-0.30.4-0.4-0.4-0.4-0.50.4
Number of licking bursts0.60.71.90.5-1.1-1.4-0.6-0.80.8-0.70.70.70.70.7-0.7
Context. condit. distance diff. score0.70.82.8-1.0-0.0-0.7-1.70.6-0.90.8-0.8-0.8-0.9-0.90.9
Locomotion velocity, session 10.91.03.0-1.51.11.70.50.9-0.90.8-0.8-0.8-0.8-0.80.8
Locomotion distance, session 10.50.63.4-1.80.20.6-0.40.4-0.70.8-0.8-0.8-0.7-0.70.7
Locomotion velocity, session 22.73.24.4-2.01.00.3-2.01.5-2.11.9-1.9-1.9-2.0-2.02.0
Locomotion distance, session 21.21.73.3-1.81.20.9-0.61.0-1.41.4-1.4-1.4-1.4-1.41.4
Locomotion velocity, session 31.31.52.1-1.41.31.2-0.21.2-1.41.3-1.3-1.3-1.3-1.31.3
Locomotion distance, session 30.40.41.2-1.10.80.90.30.6-0.60.5-0.5-0.5-0.5-0.50.5
Stereotopy head waving bouts, day 30.30.31.00.3-1.0-0.8-0.1-0.70.5-0.50.50.50.50.5-0.5
Stereotopy head waving duration, day 30.20.30.5-0.40.3-0.1-0.70.4-0.50.6-0.6-0.6-0.6-0.60.6
Locomotion velocity, session 70.30.41.1-0.6-1.10.71.1-0.30.4-0.50.50.50.40.4-0.4
Locomotion distance, session 70.60.72.1-1.40.71.20.30.9-0.80.7-0.7-0.7-0.8-0.80.8
Stereotopy head waving bouts, day 70.10.20.6-0.7-0.5-0.7-0.7-0.2-0.20.1-0.1-0.1-0.1-0.10.1
Stereotopy head waving duration, day 70.30.41.10.1-0.9-1.1-0.3-0.80.5-0.60.60.60.50.5-0.5
Locomotion velocity, session 80.50.51.7-1.2-1.30.30.9-0.70.4-0.60.60.60.50.5-0.5
Locomotion distance, session 81.21.85.2-2.30.50.4-1.11.0-1.41.4-1.4-1.4-1.4-1.41.4
Degree of sensitization distance0.30.30.5-0.60.30.5-0.20.7-0.60.6-0.6-0.6-0.6-0.60.6
Degree of sensitization stereotypy0.10.10.7-0.8-0.3-0.3-0.3-0.0-0.30.2-0.2-0.2-0.2-0.20.2
Conditioned locomotion0.60.72.8-1.30.61.71.00.8-0.50.6-0.6-0.6-0.6-0.60.6
Cocaine response after cond. corrected0.50.50.90.00.2-0.50.5-0.71.0-0.90.90.90.80.8-0.8
Cocaine response after cond. not corrected0.50.60.90.1-0.1-0.30.8-0.71.0-0.90.90.90.90.8-0.9
Cocaine response before conditioning0.20.21.2-0.5-0.41.11.00.0-0.1-0.10.10.10.20.1-0.2
Saline control response0.10.20.9-0.6-0.01.00.80.1-0.1-0.00.00.00.0-0.0-0.0
Bone: connectivity density0.91.41.90.5-1.0-0.11.4-1.31.2-1.31.31.31.31.3-1.3
Bone: cortical apparent density0.30.41.50.3-1.2-0.30.6-0.60.5-0.50.50.50.50.5-0.5
Bone: cortical area0.50.74.3-2.1-1.3-0.10.7-0.60.6-0.50.50.50.50.5-0.5
Bone: cortical porosity0.70.71.70.61.1-0.4-1.30.7-0.90.8-0.8-0.8-0.8-0.80.8
Bone: cortical porosity0.60.71.80.31.30.0-1.00.8-0.80.8-0.8-0.8-0.8-0.80.8
Bone: cortical thickness0.50.85.2-2.3-0.2-0.0-0.50.4-0.50.7-0.7-0.7-0.8-0.80.8
Bone: cortical thickness0.60.71.9-0.2-1.4-0.80.5-1.01.0-0.80.80.80.70.7-0.7
Bone: cortical tissue density0.20.31.30.3-1.1-0.30.5-0.60.5-0.50.50.50.50.5-0.5
Condit. Reinf. active minus inactive responses1.21.31.6-0.9-1.3-0.11.3-1.01.2-1.31.31.31.21.2-1.2
Condit. Reinf. active-inactive response ratio1.11.21.7-0.0-0.8-0.70.8-1.01.2-1.31.31.31.31.3-1.3
Condit. Reinf. active responses0.70.91.5-1.2-0.9-0.10.9-0.91.0-1.01.01.01.01.0-1.0
Condit. Reinf. inactive responses0.10.10.5-0.70.20.0-0.60.0-0.30.4-0.4-0.4-0.4-0.40.4
Incentive salience index mean0.50.52.0-1.4-0.8-0.00.7-0.60.6-0.70.70.70.60.7-0.6
Condit. Reinf. lever presses0.20.31.3-1.10.30.0-0.50.3-0.50.4-0.4-0.4-0.4-0.40.4
Condit. Reinf. active minus inactive responses0.20.21.2-1.1-0.10.30.6-0.20.3-0.40.40.40.50.5-0.5
Condit. Reinf. active-inactive response ratio0.30.30.6-0.8-0.2-0.20.2-0.50.6-0.50.50.50.70.6-0.7
Condit. Reinf. active responses0.20.31.5-1.20.41.20.80.5-0.40.2-0.2-0.2-0.1-0.10.1
Condit. Reinf. inactive responses0.40.51.9-0.30.21.40.60.9-0.80.6-0.6-0.6-0.6-0.60.6
Condit. Reinf. lever presses0.10.20.2-0.5-0.00.3-0.20.5-0.40.5-0.5-0.5-0.4-0.40.4
Condit. Reinf. lever reinforcers received0.20.31.6-1.30.31.10.70.4-0.30.2-0.2-0.2-0.1-0.10.1
Conditioned reinforcement - actives0.80.84.3-2.10.41.30.80.7-0.50.7-0.7-0.7-0.7-0.70.7
Conditioned reinforcement - inactives0.40.50.7-0.90.40.3-0.30.7-0.60.8-0.8-0.8-0.8-0.80.8
Conditioned locomotion0.10.10.6-0.3-0.8-0.10.1-0.20.2-0.10.10.10.10.1-0.1
Patch foraging indifference point 0 sec0.50.91.50.10.80.1-1.01.2-1.01.1-1.1-1.1-1.0-1.01.0
Patch foraging indifference point AUC3.03.46.8-2.61.41.9-0.32.2-1.81.9-1.9-1.9-1.8-1.81.9
Delay disc. indifference point, 0s delay0.80.94.4-2.10.41.71.70.6-0.40.2-0.2-0.2-0.2-0.30.3
Delay disc. indifference point, 16s delay0.70.72.10.61.31.40.90.7-0.80.6-0.6-0.6-0.6-0.60.6
Delay disc. indifference point, 2s delay1.61.84.4-1.11.82.10.81.4-1.21.1-1.1-1.1-1.3-1.21.3
Delay disc. indifference point, 24s delay1.01.02.4-0.21.51.1-0.11.3-1.11.0-1.0-1.0-0.9-0.90.8
Delay disc. indifference point, 4s delay3.53.76.4-1.72.32.50.32.0-1.91.9-1.9-1.9-1.9-2.01.9
Delay disc. indifference point, 8s delay1.41.56.1-1.11.62.51.71.0-0.60.7-0.7-0.7-0.8-0.80.7
Indifference point function ln k0.30.43.01.70.4-1.1-0.8-0.20.0-0.10.10.1-0.1-0.10.1
Indifference point function log k0.30.43.01.70.4-1.1-0.8-0.20.0-0.10.10.1-0.1-0.10.1
Patch foraging total patch changes 0 sec0.81.22.10.11.00.2-1.11.5-1.21.2-1.2-1.2-1.2-1.21.2
Patch foraging total patch changes 12 sec2.22.94.0-1.71.11.0-1.32.0-1.81.9-1.9-1.9-1.8-1.81.8
Patch foraging total patch changes 18 sec0.40.51.3-1.20.40.90.30.9-0.60.6-0.6-0.6-0.5-0.60.5
Patch foraging total patch changes 24 sec2.42.94.0-0.91.21.0-1.22.0-1.92.0-2.0-2.0-1.9-1.91.9
Patch foraging total patch changes 6 sec1.72.63.4-1.11.10.7-1.41.9-1.81.8-1.8-1.8-1.8-1.81.8
Patch foraging time to switch 0 sec3.04.76.02.4-1.3-0.61.9-2.52.4-2.32.32.32.42.4-2.4
Patch foraging water rate 0 sec2.74.49.0-3.01.11.2-1.12.4-2.32.1-2.1-2.1-2.2-2.22.3
Patch foraging water rate 12 sec2.74.19.1-3.00.80.0-2.11.8-2.22.1-2.1-2.1-2.2-2.12.1
Patch foraging water rate 18 sec1.11.52.6-0.50.7-0.2-1.61.2-1.61.3-1.3-1.3-1.4-1.31.3
Patch foraging water rate 24 sec1.21.64.7-0.90.5-1.1-2.21.0-1.61.2-1.2-1.2-1.3-1.31.3
Patch foraging water rate 6 sec0.50.84.0-2.00.10.8-0.10.9-1.00.7-0.7-0.7-0.7-0.70.7
Seeking ratio, delayed vs. immediate footshock0.00.00.20.50.30.20.3-0.10.20.00.00.00.1-0.0-0.2
Distance traveled before self-admin0.20.21.8-0.1-0.2-1.0-1.4-0.2-0.10.0-0.0-0.00.00.10.0
Distance traveled after self-admin0.10.11.2-1.10.3-0.3-0.30.1-0.10.1-0.1-0.1-0.1-0.10.1
Extensor digitorum longus weight0.10.21.1-0.1-0.7-1.0-0.9-0.20.0-0.10.10.10.10.1-0.1
Bone: elastic displacement0.30.30.90.7-0.9-0.8-0.3-0.70.3-0.30.30.30.30.3-0.3
Bone: elastic work1.41.85.11.3-2.0-2.3-0.8-1.71.1-1.01.01.01.11.1-1.1
Bone: endosteal estimation1.53.34.30.8-1.7-0.31.8-1.92.1-2.12.12.12.02.0-2.0
Bone: endosteal perimeter1.63.34.8-0.1-2.00.12.2-1.72.0-2.02.02.02.02.0-2.0
Epididymis fat weight0.71.59.20.80.2-2.2-3.00.3-0.70.7-0.7-0.7-0.8-0.80.8
Delta time in closed arm before/after self-admin0.50.51.30.40.70.1-1.10.7-0.80.7-0.7-0.7-0.7-0.70.7
Delta time in open arm before/after self-admin1.31.22.8-1.21.71.50.81.2-1.20.9-0.9-0.9-0.9-0.90.9
Diff in mean of infusions in LGA sessions0.30.40.70.2-0.7-0.30.2-0.80.9-0.60.60.60.60.7-0.7
Delay discount exponential model param2.72.87.61.0-2.2-2.8-1.0-1.81.5-1.51.51.51.61.6-1.5
Extinction: sum of active levers before priming0.30.31.1-0.8-0.30.61.0-0.20.4-0.50.50.50.50.5-0.5
Active lever presses in extinction session 60.40.41.8-1.30.60.4-0.40.5-0.60.5-0.5-0.5-0.6-0.50.6
Bone: final force0.40.71.8-1.3-1.4-0.9-0.1-0.70.7-0.70.70.70.70.7-0.7
Bone: final moment0.30.42.1-1.5-1.1-0.6-0.1-0.50.4-0.30.30.30.40.4-0.4
Food consumed during 24 hour testing period0.00.00.0-0.2-0.00.2-0.10.1-0.10.2-0.2-0.2-0.2-0.20.2
Glucose1.42.15.5-0.70.4-0.7-2.31.1-1.51.6-1.6-1.6-1.6-1.61.6
Heart weight0.71.01.31.1-0.80.11.1-0.81.1-1.01.01.01.01.0-1.1
Delay discount hyperbolic model param2.93.18.31.2-2.3-2.9-1.1-1.81.5-1.51.51.51.61.6-1.5
Intermittent access intake day 1-15 change0.30.30.50.7-0.0-0.30.3-0.70.7-0.50.50.50.50.5-0.5
Intermittent access intake escalation1.31.32.11.0-0.6-0.70.9-1.31.5-1.21.21.21.21.2-1.2
Intermittent access intake escalation 20.10.10.30.10.30.40.60.00.1-0.00.00.00.00.0-0.0
Intermitt. access day 1 inactive lever presses1.41.52.61.4-0.8-1.5-0.1-1.61.3-1.21.21.21.21.2-1.2
Intermitt. access day 15 inactive lever presses0.20.21.11.00.2-0.6-0.9-0.1-0.20.1-0.1-0.1-0.1-0.10.1
Intermitt. access escalation Index0.40.40.90.20.7-0.5-1.00.6-0.60.6-0.6-0.6-0.6-0.60.6
Intermittent access day 1 total infusions0.10.10.30.50.2-0.4-0.50.3-0.30.2-0.2-0.2-0.2-0.20.2
Intermittent access day 15 total infusions0.70.71.61.3-0.4-0.90.2-0.91.0-0.90.90.90.90.9-0.9
Intermittent access terminal intake (last 3 days)0.10.10.60.8-0.2-0.5-0.1-0.40.3-0.20.20.20.20.2-0.2
Intermittent access total infusions0.10.10.60.70.80.1-0.00.3-0.20.3-0.3-0.3-0.3-0.30.3
Intermittent access day 1 locomotion0.20.20.80.9-0.2-0.8-0.7-0.20.0-0.10.10.10.10.1-0.1
Intermittent access day 15 total locomotion0.20.30.30.5-0.2-0.10.5-0.50.5-0.60.60.60.60.6-0.6
Intermittent access total locomotion0.10.10.50.7-0.00.30.7-0.20.2-0.30.30.30.30.3-0.3
Intermittent access standard deviation0.60.61.71.3-0.4-0.10.9-0.80.8-0.70.70.70.70.7-0.7
Left kidney weight0.41.21.8-0.31.10.5-1.01.3-1.31.2-1.2-1.2-1.1-1.11.1
Right kidney weight0.72.02.9-1.21.31.1-0.81.7-1.61.5-1.5-1.5-1.4-1.51.5
Cocaine induced anxiety0.20.20.40.6-0.3-0.50.1-0.70.5-0.50.50.50.50.5-0.5
Post-drug Anxiety4.14.65.82.2-2.1-1.70.8-2.42.3-2.32.32.32.32.3-2.3
Baseline Anxiety2.83.03.81.2-2.0-0.81.2-1.81.9-1.91.91.91.91.9-1.9
Tail length0.41.36.30.50.3-1.6-2.50.7-1.00.8-0.8-0.8-1.0-0.91.0
Length with tail1.03.56.41.3-2.5-2.10.1-1.81.9-2.02.02.01.91.9-1.9
Length without tail4.49.713.71.4-3.7-1.32.5-3.23.6-3.43.43.43.53.4-3.4
Times rat made contact with spout0.40.51.00.60.6-0.2-1.00.7-0.60.7-0.7-0.7-0.7-0.70.7
Lifetime Intake0.10.10.20.50.40.30.30.1-0.00.1-0.1-0.1-0.1-0.10.1
Liver weight, left0.50.91.3-1.10.70.4-0.71.1-1.01.1-1.1-1.1-0.9-0.90.9
Liver weight, right0.71.22.8-0.2-0.8-1.7-0.6-1.11.1-1.21.21.21.11.2-1.1
Locomotor activity1.01.64.91.6-1.4-2.2-1.1-1.21.0-0.90.90.91.00.9-1.1
Locomotor testing distance0.91.55.01.0-1.9-2.2-1.0-1.21.0-0.90.90.90.90.9-1.0
Locomotor testing rearing0.30.42.0-0.8-0.7-1.4-1.3-0.30.1-0.20.20.20.20.2-0.3
Locomotion in novel chamber3.03.77.8-1.72.82.3-0.11.9-1.71.9-1.9-1.9-1.8-1.91.8
Locomotion in novel chamber post-restriction0.91.15.8-1.60.42.22.40.6-0.0-0.20.20.20.10.2-0.1
Fecal boli incidents, locomotor time 10.50.52.3-1.50.40.90.50.6-0.60.5-0.5-0.5-0.6-0.60.6
Change in fecal boli incidents, locomotor task0.20.21.00.70.71.00.70.10.2-0.00.00.00.20.1-0.2
Time >=10cm from walls, locomotor time 10.10.10.3-0.30.40.50.00.3-0.30.3-0.3-0.3-0.5-0.40.3
Bouts of movement, locomotor time 11.01.12.4-0.81.50.8-0.61.2-0.91.2-1.2-1.2-0.8-0.90.9
Total resting periods, locomotor time 10.40.40.7-0.70.80.3-0.50.7-0.50.8-0.8-0.8-0.4-0.50.5
Rest time, locomotor task time 11.51.74.3-2.11.71.90.51.4-0.71.2-1.2-1.2-0.9-0.90.8
Distance moved, locomotor task time 10.20.20.90.4-0.4-1.0-1.0-0.1-0.5-0.00.00.0-0.2-0.30.3
Vertical activity count, locomotor time 10.30.41.51.2-0.4-0.9-0.5-0.50.1-0.40.40.40.60.4-0.6
Time >=10cm from walls, locomotor time 20.10.10.20.5-0.3-0.4-0.2-0.30.2-0.00.00.00.20.1-0.2
Bouts of movement, locomotor time 20.91.01.6-0.81.20.5-0.51.0-1.30.9-0.9-0.9-1.3-1.11.3
Total resting periods, locomotor time 20.70.81.7-0.41.30.4-0.40.9-1.00.8-0.8-0.8-1.1-0.91.1
Rest time, locomotor task time 20.60.72.1-0.81.31.50.60.9-0.20.9-0.9-0.9-0.4-0.60.3
Distance moved, locomotor task time 20.20.20.7-0.1-0.8-0.7-0.1-0.40.1-0.40.40.40.30.4-0.2
Vertical activity count, locomotor time 21.01.11.70.4-1.2-0.41.0-1.00.9-1.21.21.21.21.3-1.2
Light reinforcement 10.00.10.2-0.5-0.1-0.2-0.40.3-0.30.2-0.2-0.2-0.2-0.10.2
Light reinforcement 20.30.31.10.4-0.2-1.1-0.5-0.60.5-0.50.50.50.60.6-0.6
Bone: marrow area1.63.54.50.8-1.9-0.41.8-1.92.1-2.12.12.12.12.1-2.1
Bone: maximum diameter0.61.13.3-1.8-1.01.01.8-0.40.8-0.80.80.80.70.7-0.7
Bone: maximum force1.01.73.4-0.1-1.9-1.50.0-1.41.3-1.31.31.31.31.3-1.3
Bone: maximum moment0.61.02.5-0.2-1.6-1.3-0.0-1.21.0-0.90.90.91.01.0-1.0
Mean time between licks in bursts0.60.91.50.8-0.4-0.01.2-0.81.0-1.01.01.01.01.1-1.0
Mean num. licks in bursts1.11.42.70.01.71.50.11.3-1.21.2-1.2-1.2-1.2-1.21.2
Cd content in liver0.40.42.2-0.30.00.91.5-0.50.4-0.50.50.50.50.5-0.5
Co content in liver0.20.20.80.70.9-0.3-0.70.3-0.60.3-0.3-0.3-0.3-0.30.3
Cu content in liver0.20.21.0-0.80.51.00.90.20.1-0.00.00.00.00.0-0.0
Fe content in liver0.60.71.0-1.00.70.6-0.51.0-0.90.9-0.9-0.9-0.9-0.90.9
K content in liver3.03.04.62.1-2.0-1.80.4-1.81.7-1.71.71.71.71.7-1.7
Mg content in liver0.10.20.80.5-0.9-0.30.2-0.30.2-0.30.30.30.30.3-0.3
Mn content in liver0.10.10.90.90.5-0.1-0.00.1-0.00.1-0.1-0.1-0.1-0.10.1
Na content in liver0.20.20.6-0.3-0.8-0.4-0.70.1-0.30.3-0.3-0.3-0.3-0.30.3
Rb content in liver1.61.94.50.8-1.00.52.1-1.31.2-1.51.51.51.51.5-1.5
Se content in liver1.61.93.2-1.71.01.80.11.7-1.41.3-1.3-1.3-1.3-1.31.3
Sr content in liver0.30.20.30.2-0.4-0.5-0.1-0.50.4-0.50.50.50.50.5-0.5
Zn content in liver1.01.14.9-1.60.52.21.60.9-0.50.5-0.5-0.5-0.5-0.50.5
Bone: minimum diameter1.32.43.2-0.7-1.8-0.11.7-1.61.8-1.71.71.71.61.6-1.6
Time in familiar zone, hab. session 13.33.14.4-0.71.50.6-1.71.8-2.12.0-2.0-2.0-2.0-2.02.0
Time in novel zone, hab. session 11.81.82.40.7-0.9-0.41.5-1.31.5-1.51.51.51.51.5-1.5
Total zone transitions, hab. session 10.81.11.7-1.30.40.0-1.20.7-1.01.1-1.1-1.1-1.1-1.11.1
Total locomotion distance, hab. session 10.81.23.0-1.70.4-0.0-1.30.8-0.91.2-1.2-1.2-1.1-1.11.1
Locomotion velocity, hab. session 10.50.83.4-1.80.1-0.1-1.10.5-0.50.9-0.9-0.9-0.7-0.80.7
Time in familiar zone, hab. session 20.50.52.81.7-0.4-0.9-0.2-0.70.5-0.60.60.60.60.6-0.6
Time in novel zone, hab. session 21.11.13.0-1.71.00.9-0.41.0-1.01.1-1.1-1.1-1.0-1.01.0
Total zone transitions, hab. session 20.20.31.0-0.1-0.5-1.0-0.5-0.80.6-0.40.40.40.50.5-0.5
Total locomotion distance, hab. session 20.10.10.5-0.3-0.2-0.6-0.7-0.30.20.1-0.1-0.10.10.1-0.1
Locomotion velocity, hab. session 20.10.10.30.0-0.4-0.5-0.4-0.50.4-0.20.20.20.30.3-0.3
Novel to familiar place preference ratio0.00.00.30.5-0.1-0.3-0.2-0.10.1-0.00.00.00.10.1-0.1
Novelty place preference0.10.10.30.6-0.4-0.5-0.4-0.10.10.0-0.0-0.00.00.0-0.0
Time in novel zone, NPP test0.10.10.20.4-0.1-0.3-0.50.2-0.30.3-0.3-0.3-0.3-0.30.3
Total zone transitions, NPP test0.50.72.2-1.50.0-0.1-1.20.4-0.70.8-0.8-0.8-0.8-0.80.8
Total locomotion distance, NPP test0.30.42.2-1.5-0.1-0.3-1.10.2-0.30.6-0.6-0.6-0.4-0.40.4
Locomotion velocity, NPP test0.30.41.2-1.1-1.0-1.1-1.0-0.60.4-0.10.10.10.30.3-0.3
Intraocular pressure0.30.41.31.20.5-0.50.0-0.60.8-0.60.60.60.60.6-0.7
Delta distance traveled before/after self-admin0.10.10.3-0.60.1-0.00.50.00.1-0.00.00.00.10.0-0.1
Delta ambulatory time before/after self-admin0.30.31.0-0.2-0.3-0.21.0-0.50.7-0.60.60.60.60.6-0.7
Parametrial fat weight1.63.012.5-0.40.6-1.8-3.51.2-1.71.6-1.6-1.6-1.7-1.61.8
Pavlov. Cond. lever latency0.81.02.21.5-0.5-0.70.5-0.91.2-1.11.11.11.11.1-1.1
Pavlov. Cond. magazine entry latency0.40.61.9-1.40.41.00.30.8-0.70.6-0.6-0.6-0.7-0.70.7
Pavlov. Cond. change in total contacts0.60.71.8-1.30.50.7-0.30.8-0.90.8-0.8-0.8-0.8-0.80.8
Pavlov. Cond. index score0.60.82.7-1.60.20.8-0.20.8-1.00.9-0.9-0.9-0.9-0.90.9
Pavlov. Cond. latency score0.60.83.1-1.70.10.9-0.00.8-0.90.8-0.8-0.8-0.9-0.90.9
Pavlov. Cond. lever contacts0.70.81.2-1.10.30.3-0.80.8-1.11.0-1.0-1.0-1.0-1.01.0
Pavlov. Cond. magazine entry number0.30.41.71.3-0.2-0.8-0.1-0.60.6-0.60.60.60.60.6-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.20.40.10.0-0.40.3-0.20.3-0.3-0.3-0.3-0.30.3
Pavlov. Cond. lever-magazine prob. diff.0.60.72.4-1.50.30.8-0.10.8-0.90.8-0.8-0.8-0.8-0.80.8
Pavlov. Cond. response bias0.70.81.2-1.10.50.4-0.70.8-1.01.0-1.0-1.0-1.0-1.01.0
Pavlov. Cond. lever latency0.20.31.40.11.20.70.20.4-0.50.4-0.4-0.4-0.4-0.40.4
Pavlov. Cond. magazine entry latency0.30.31.4-1.2-0.6-0.7-0.8-0.0-0.10.3-0.3-0.3-0.4-0.30.4
Pavlov. Cond. change in total contacts0.10.21.0-0.2-0.5-1.0-0.9-0.10.00.1-0.1-0.1-0.2-0.20.2
Pavlov. Cond. index score0.30.41.1-0.9-0.8-0.8-1.10.2-0.20.4-0.4-0.4-0.5-0.50.5
Pavlov. Cond. latency score0.30.41.4-0.8-0.6-0.8-1.20.2-0.30.5-0.5-0.5-0.6-0.50.6
Pavlov. Cond. lever contacts0.20.21.1-0.0-1.1-0.9-0.5-0.30.4-0.30.20.20.20.2-0.2
Pavlov. Cond. magazine entry number0.20.31.00.91.00.70.70.2-0.1-0.10.10.10.30.2-0.3
Pavlov. Cond. intertrial magazine entries0.20.31.51.2-0.2-0.00.4-0.30.3-0.40.40.40.50.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.30.41.4-0.7-0.7-0.8-1.20.2-0.30.5-0.5-0.5-0.5-0.50.5
Pavlov. Cond. response bias0.30.42.1-0.3-1.5-0.60.1-0.60.7-0.50.50.50.50.5-0.5
Time in closed arm before self-admin1.21.42.00.8-1.4-1.30.4-1.31.3-1.21.21.21.11.1-1.3
Time in closed arm after self-admin0.40.42.20.5-0.2-1.5-1.4-0.30.2-0.10.10.10.00.1-0.1
Time in open arm before self-admin0.40.40.7-0.70.30.3-0.80.5-0.50.7-0.7-0.7-0.7-0.70.7
Time in open arm after self-admin0.91.02.1-1.01.51.40.31.0-1.00.9-0.9-0.9-0.9-0.91.0
Bone: periosteal estimation1.02.13.0-1.0-1.7-0.01.7-1.41.6-1.61.61.61.51.5-1.5
Bone: periosteal perimeter1.52.45.4-0.8-2.3-0.81.2-1.61.7-1.71.71.71.61.6-1.6
Bone: post-yield work0.40.61.41.1-0.9-1.2-0.1-0.80.7-0.60.60.60.70.7-0.7
Progressive ratio test 1 active lever presses1.11.12.81.4-0.9-1.7-0.6-1.11.0-0.90.90.90.90.9-0.9
Progressive ratio test 1 breakpoint1.31.33.01.5-1.0-1.7-0.5-1.31.1-1.11.11.11.11.1-1.1
Progressive ratio test 1 inactive lever presses0.30.41.71.0-0.4-1.3-0.7-0.60.3-0.40.40.40.40.4-0.4
Progressive ratio test 2 active lever presses0.10.10.6-0.00.3-0.6-0.7-0.1-0.00.1-0.1-0.1-0.1-0.10.1
Progressive ratio test 2 breakpoint0.20.21.0-0.00.5-0.6-1.00.1-0.30.4-0.4-0.4-0.4-0.40.4
Progressive ratio test 2 inactive lever presses0.80.91.2-0.70.90.5-0.51.0-1.11.0-1.0-1.0-1.0-1.01.0
Incentive Sensitization - Responses2.02.02.5-0.91.50.2-1.51.4-1.41.6-1.6-1.6-1.6-1.61.6
Incentive Sensitization - Breakpoint2.02.02.5-1.01.40.3-1.41.4-1.41.6-1.6-1.6-1.6-1.61.6
Sum of active levers in priming session hrs 5-61.61.57.9-1.10.72.82.80.7-0.00.2-0.2-0.2-0.2-0.20.2
Progressive ratio2.93.48.41.4-2.9-1.40.7-1.91.8-2.02.02.01.81.8-1.8
Food seeking constrained by brief footshock3.03.75.51.4-2.3-1.61.3-2.11.9-2.12.12.12.02.0-1.9
Seeking ratio, punishment vs. effort0.20.20.7-0.60.80.30.20.3-0.40.4-0.4-0.4-0.3-0.30.4
Retroperitoneal fat weight0.62.16.5-1.11.0-0.5-2.51.3-1.41.4-1.4-1.4-1.4-1.41.4
Reaction time number correct2.74.06.2-2.51.72.30.22.1-2.02.0-2.0-2.0-2.0-2.02.0
Reaction time mean minus median1.31.85.11.5-2.3-1.2-0.0-1.51.3-1.21.21.21.21.2-1.2
Reaction time mean minus median AUC2.22.86.51.6-2.5-1.40.3-1.81.7-1.71.71.71.71.7-1.6
Reaction time num false alarms0.81.11.8-0.71.21.30.01.4-1.01.1-1.1-1.1-1.1-1.11.0
Reaction time num false alarms AUC1.11.52.4-0.61.41.3-0.21.6-1.21.3-1.3-1.3-1.3-1.31.3
Reaction time trials correct on left2.74.06.2-2.51.72.30.22.1-2.02.0-2.0-2.0-2.0-2.02.0
Reaction time trials on left2.84.06.1-2.51.62.30.12.1-2.12.1-2.1-2.1-2.0-2.02.0
Reaction time mean2.53.58.83.0-1.8-2.5-0.7-2.01.5-1.71.71.71.71.7-1.6
Reaction time mean AUC2.73.77.52.7-2.1-2.5-0.6-2.01.6-1.81.81.81.81.8-1.7
Median of all reaction times2.12.98.22.9-1.3-2.5-0.9-1.71.3-1.51.51.51.51.5-1.4
Reaction time omissions0.20.31.30.8-0.6-0.7-1.2-0.0-0.10.3-0.3-0.3-0.3-0.30.3
Reaction time false alarm rate0.00.00.30.60.40.0-0.20.3-0.00.1-0.1-0.1-0.1-0.10.0
Reaction time premature initiation rate0.10.20.5-0.10.5-0.3-0.70.4-0.30.5-0.5-0.5-0.3-0.30.2
Reaction time premature initiations1.01.31.8-1.31.00.7-0.71.3-1.21.4-1.4-1.4-1.2-1.21.1
Std. dev. reaction times2.12.95.32.3-2.2-2.2-0.7-1.91.5-1.51.51.51.51.5-1.5
Reaction time trials completed2.84.06.1-2.51.62.30.12.1-2.12.1-2.1-2.1-2.0-2.02.0
Reaction time trials AUC2.73.96.4-2.51.52.20.02.1-2.12.0-2.0-2.0-2.0-2.02.0
Run reversals in cocaine runway, females1.61.54.0-0.3-2.0-1.00.8-1.21.1-1.31.31.31.31.3-1.2
Run reversals in cocaine runway, males0.40.30.7-0.20.5-0.1-0.80.8-0.60.6-0.6-0.6-0.6-0.60.6
Latency to leave start box in cocaine runway2.32.47.31.6-1.3-2.7-0.7-1.61.3-1.51.51.51.41.4-1.5
Latency to leave start box in cocaine runway, F2.42.64.41.1-1.8-2.10.2-1.61.6-1.71.71.71.71.7-1.7
Latency to leave start box in cocaine runway, M0.40.42.50.30.3-1.4-1.6-0.3-0.10.0-0.0-0.0-0.1-0.00.1
Std. dev. time between licks in bursts0.30.41.50.00.30.71.2-0.30.5-0.60.60.60.60.6-0.6
Total sessions with >9 infusions0.10.10.20.1-0.1-0.0-0.40.4-0.40.4-0.4-0.4-0.4-0.40.4
Short access day 1 total inactive lever presses0.80.91.2-1.10.90.7-0.10.9-1.01.0-1.0-1.0-1.0-1.01.0
Short access day 10 total inactive lever presses0.50.50.7-0.70.40.5-0.40.7-0.70.9-0.9-0.9-0.9-0.90.8
Short access day 1 total infusions0.60.60.8-0.70.90.5-0.10.8-0.70.9-0.9-0.9-0.9-0.90.8
Short access day 10 total infusions0.10.21.11.0-0.2-0.40.0-0.30.3-0.30.30.30.30.3-0.3
Short access total infusions0.00.00.20.50.00.10.20.10.10.1-0.1-0.1-0.1-0.10.1
Short access day 1 locomotion0.30.30.60.1-0.8-0.10.6-0.50.6-0.50.50.50.50.5-0.5
Short access day 10 total locomotion0.20.20.80.1-0.9-0.00.6-0.50.5-0.40.40.40.40.4-0.4
Short access total locomotion0.10.20.6-0.2-0.70.40.8-0.20.3-0.30.30.30.30.3-0.3
One hour access (0.3 mA shock)0.80.93.1-0.91.21.80.80.8-0.70.8-0.8-0.8-0.8-0.80.8
Compulsive drug intake0.10.10.80.10.40.60.9-0.20.1-0.20.20.20.20.2-0.2
One hour access (shock baseline)0.10.10.2-0.10.5-0.0-0.30.3-0.20.3-0.3-0.3-0.3-0.30.3
Social response proportion0.20.20.70.7-0.80.10.6-0.30.4-0.30.30.30.30.3-0.2
Social responses0.20.30.60.8-0.7-0.00.5-0.60.5-0.40.40.40.50.5-0.5
Social time2.83.76.3-2.31.62.50.22.1-2.01.9-1.9-1.9-1.9-1.91.9
Soleus weight0.10.20.8-0.9-0.7-0.9-0.7-0.40.3-0.20.20.20.20.3-0.2
Bone: stiffness0.10.10.3-0.3-0.5-0.3-0.2-0.10.2-0.30.30.30.30.3-0.3
Tibialis anterior weight0.20.72.0-1.40.3-0.2-1.10.9-0.80.8-0.8-0.8-0.8-0.80.8
Time to tail flick, vehicle, before self-admin0.10.10.5-0.7-0.6-0.1-0.1-0.00.1-0.10.10.10.20.2-0.2
Time to tail flick, vehicle, after self-admin1.01.11.80.5-1.2-0.41.3-1.11.1-1.11.11.11.01.1-0.9
Time to tail flick, test, before self-admin2.32.38.5-1.41.82.92.01.3-0.61.1-1.1-1.1-1.1-1.11.1
Time to tail flick, test, after self-admin0.20.22.6-1.60.10.10.1-0.10.2-0.00.00.0-0.2-0.10.1
Delta time to tail flick, vehicle, before/after SA0.20.21.20.1-0.20.41.1-0.30.5-0.30.30.30.20.2-0.2
Delta time to tail flick, test, before/after SA1.00.95.00.2-0.7-2.2-1.9-0.70.2-0.50.50.50.30.3-0.3
Tibia length0.82.27.3-2.71.61.4-0.31.6-1.41.3-1.3-1.3-1.2-1.21.2
Ambulatory time before self-admin1.01.04.3-0.50.5-0.5-2.10.8-1.01.0-1.0-1.0-1.0-0.91.0
Ambulatory time after self-admin0.30.31.9-1.4-0.2-0.8-1.00.1-0.30.3-0.3-0.3-0.3-0.20.2
Bone: tissue strength0.40.40.8-0.10.80.2-0.70.8-0.90.7-0.7-0.7-0.5-0.50.5
Total heroin consumption0.00.00.30.20.60.20.10.10.10.1-0.1-0.1-0.1-0.10.1
Bone: trabecular number0.60.91.9-0.8-1.30.31.4-0.90.9-0.90.90.90.90.9-0.9
Bone: trabecular spacing2.22.84.0-0.51.80.6-1.62.0-1.81.9-1.9-1.9-1.8-1.81.8
Bone: trabecular thickness2.73.26.5-0.0-1.70.22.6-1.92.0-1.91.91.91.91.9-1.9
Bone: trabecular tissue density3.75.17.8-2.82.52.7-0.02.5-2.32.1-2.1-2.1-2.2-2.22.2
Water consumed over 24 hours1.41.72.3-0.80.90.7-1.01.4-1.51.5-1.5-1.5-1.5-1.51.5
Number of responses in last shaping day0.60.61.2-1.11.0-0.0-0.60.8-0.80.8-0.8-0.8-0.8-0.80.8