Hub : Genes

Tcp11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Tcp11 0.07 0.04 2.1e-06 0.05 0.06 0.06 0.06 2.3e-05 2.3e-06 6.2e-06 2.6e-06
2 pVTA gene expression Tcp11 0.06 0.05 5.8e-04 0.02 0.02 0.01 0.02 1.5e-02 7.9e-03 4.7e-02 1.4e-02
3 IL gene expression Tcp11 0.15 0.09 1.6e-03 0.12 0.09 0.11 0.1 6.8e-04 3.9e-03 1.2e-03 1.7e-03
4 LHb gene expression Tcp11 0.18 0.1 3.4e-03 0.06 0.07 0.06 0.07 1.4e-02 1.2e-02 1.5e-02 8.6e-03
5 BLA gene expression Tcp11 0.2 0.13 6.5e-08 0.17 0.14 0.14 0.16 2.5e-09 5.5e-08 4.3e-08 5.8e-09
6 PL gene expression Tcp11 0.11 0.06 6.7e-16 0.15 0.14 0.14 0.14 5.5e-16 5.2e-15 3.3e-15 1.7e-15
7 NAcc gene expression Tcp11 0.33 0.12 0.0e+00 0.27 0.28 0.28 0.28 5.7e-41 1.2e-41 2.8e-43 1.5e-42

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.00.00.10.20.10.00.1-0.2-0.20.1
Area under the delay curve0.00.00.1-0.20.30.30.30.20.2-0.0
BMI with tail2.910.212.63.53.5-3.13.2-3.0-3.0-3.0
BMI without tail0.84.46.02.22.5-2.22.2-1.7-1.8-2.0
Body weight1.04.46.61.12.1-2.12.6-2.0-2.0-2.4
Weight adjusted by age0.10.20.9-0.9-0.3-0.00.20.30.30.1
Bone surface0.20.40.7-0.8-0.80.5-0.70.40.40.7
Bone volume0.00.00.0-0.1-0.00.1-0.0-0.1-0.10.1
Breakpoint value in progressive ratio session0.71.22.21.00.6-0.71.0-1.5-1.5-1.1
Number of licking bursts0.41.21.9-1.1-1.41.3-1.21.01.00.8
Context. condit. distance diff. score2.93.64.7-2.1-2.21.6-2.01.81.81.7
Locomotion velocity, session 13.43.94.6-2.0-1.82.0-1.92.01.92.1
Locomotion distance, session 11.82.33.6-0.9-1.31.7-1.81.51.51.9
Locomotion velocity, session 21.21.42.1-1.2-1.40.9-1.31.11.11.1
Locomotion distance, session 20.71.01.7-0.8-0.91.0-1.10.90.91.3
Locomotion velocity, session 30.40.50.8-0.2-0.20.4-0.90.80.80.8
Locomotion distance, session 31.01.11.7-0.6-0.60.8-1.31.31.31.3
Stereotopy head waving bouts, day 30.20.20.7-0.8-0.60.2-0.40.30.30.2
Stereotopy head waving duration, day 30.40.61.0-1.0-0.80.6-0.60.70.70.6
Locomotion velocity, session 70.70.71.3-0.7-0.40.8-0.81.01.01.1
Locomotion distance, session 71.62.03.0-1.2-1.01.4-1.41.61.61.7
Stereotopy head waving bouts, day 70.10.10.2-0.10.20.0-0.30.50.50.3
Stereotopy head waving duration, day 70.00.00.20.20.4-0.30.10.10.1-0.2
Locomotion velocity, session 83.94.76.8-2.6-2.51.9-2.12.02.01.9
Locomotion distance, session 83.04.35.5-2.0-2.21.8-2.32.02.02.2
Degree of sensitization distance0.10.10.2-0.5-0.40.10.2-0.3-0.3-0.1
Degree of sensitization stereotypy0.20.20.40.00.00.2-0.50.60.60.5
Conditioned locomotion1.31.62.30.80.8-1.51.3-1.3-1.3-1.5
Cocaine response after cond. corrected0.50.81.01.00.8-0.90.8-0.9-0.9-1.0
Cocaine response after cond. not corrected0.00.10.10.10.0-0.30.1-0.2-0.2-0.4
Cocaine response before conditioning1.61.93.1-1.8-1.51.1-1.31.31.41.3
Saline control response3.85.35.62.32.3-2.42.4-2.4-2.4-2.1
Bone: connectivity density0.00.00.1-0.1-0.20.10.0-0.1-0.00.2
Bone: cortical apparent density1.21.82.61.61.4-1.41.2-1.4-1.3-1.2
Bone: cortical area0.10.10.3-0.2-0.20.6-0.20.20.20.3
Bone: cortical porosity1.11.21.7-1.0-0.61.1-1.01.31.21.3
Bone: cortical porosity1.81.92.6-1.5-0.91.5-1.01.61.51.5
Bone: cortical thickness0.40.72.21.51.2-0.10.5-0.7-0.7-0.2
Bone: cortical thickness3.13.86.02.42.0-1.61.7-2.1-2.0-1.6
Bone: cortical tissue density1.01.62.11.51.2-1.31.1-1.3-1.2-1.1
Condit. Reinf. active minus inactive responses0.30.30.5-0.7-0.40.5-0.40.70.70.7
Condit. Reinf. active-inactive response ratio0.60.60.90.70.7-0.90.9-0.8-0.8-0.8
Condit. Reinf. active responses0.00.00.0-0.10.1-0.10.20.10.10.1
Condit. Reinf. inactive responses0.00.10.10.30.4-0.20.3-0.2-0.2-0.0
Incentive salience index mean0.91.21.6-1.3-1.01.0-0.91.21.21.1
Condit. Reinf. lever presses1.01.52.0-1.4-1.21.3-1.11.21.21.1
Condit. Reinf. active minus inactive responses0.81.31.8-1.2-1.00.8-1.01.31.31.0
Condit. Reinf. active-inactive response ratio0.40.71.1-1.0-0.80.5-0.71.00.90.7
Condit. Reinf. active responses0.81.11.6-1.1-1.00.9-1.01.31.21.0
Condit. Reinf. inactive responses0.00.00.00.20.10.0-0.0-0.00.00.1
Condit. Reinf. lever presses1.31.82.2-1.3-1.41.2-1.21.51.41.4
Condit. Reinf. lever reinforcers received1.31.82.3-1.3-1.31.2-1.31.51.51.4
Conditioned reinforcement - actives0.00.00.2-0.20.20.10.40.10.10.1
Conditioned reinforcement - inactives0.10.20.5-0.5-0.2-0.2-0.40.70.70.4
Conditioned locomotion0.10.10.3-0.50.30.00.60.30.3-0.0
Patch foraging indifference point 0 sec0.92.73.01.71.7-1.41.6-1.6-1.7-1.7
Patch foraging indifference point AUC0.92.12.7-1.5-1.61.2-1.61.41.41.3
Delay disc. indifference point, 0s delay0.10.10.2-0.5-0.30.3-0.20.40.40.3
Delay disc. indifference point, 16s delay0.10.20.6-0.00.40.80.10.40.40.2
Delay disc. indifference point, 2s delay0.50.61.0-1.0-0.70.8-0.30.80.80.6
Delay disc. indifference point, 24s delay0.10.20.80.10.90.20.60.10.1-0.2
Delay disc. indifference point, 4s delay0.10.10.2-0.10.2-0.50.3-0.2-0.2-0.3
Delay disc. indifference point, 8s delay0.10.10.3-0.10.5-0.10.60.00.0-0.2
Indifference point function ln k0.10.40.5-0.5-0.60.7-0.60.60.50.6
Indifference point function log k0.10.40.5-0.5-0.60.7-0.60.60.50.6
Patch foraging total patch changes 0 sec0.92.63.31.71.8-1.41.6-1.6-1.6-1.6
Patch foraging total patch changes 12 sec0.10.20.40.60.3-0.20.2-0.5-0.5-0.4
Patch foraging total patch changes 18 sec1.43.44.32.11.9-1.81.5-1.9-1.8-1.8
Patch foraging total patch changes 24 sec0.31.12.11.41.3-1.00.9-0.8-0.8-0.8
Patch foraging total patch changes 6 sec1.11.82.61.61.6-1.41.2-1.2-1.3-1.2
Patch foraging time to switch 0 sec1.87.07.72.72.6-2.52.6-2.8-2.8-2.5
Patch foraging water rate 0 sec0.10.40.6-0.7-0.50.7-0.50.80.80.6
Patch foraging water rate 12 sec0.00.20.30.30.10.1-0.50.50.60.4
Patch foraging water rate 18 sec0.10.20.50.30.4-0.30.7-0.2-0.1-0.6
Patch foraging water rate 24 sec0.00.00.20.1-0.10.1-0.40.20.20.2
Patch foraging water rate 6 sec0.10.20.5-0.1-0.20.5-0.70.40.50.5
Seeking ratio, delayed vs. immediate footshock0.20.30.50.60.1-0.7-0.1-0.7-0.7-0.5
Distance traveled before self-admin0.10.30.50.30.1-0.60.1-0.7-0.7-0.7
Distance traveled after self-admin0.40.61.10.40.1-1.10.4-0.9-0.9-1.1
Extensor digitorum longus weight0.72.84.4-2.1-2.11.8-1.51.31.31.4
Bone: elastic displacement0.30.40.7-0.30.20.5-0.40.80.80.9
Bone: elastic work0.10.10.40.20.6-0.10.30.10.10.2
Bone: endosteal estimation0.10.31.3-1.1-0.6-0.30.4-0.2-0.3-0.7
Bone: endosteal perimeter0.10.20.9-1.0-0.8-0.2-0.00.00.0-0.4
Epididymis fat weight6.131.048.26.96.5-5.55.0-5.0-5.0-4.6
Delta time in closed arm before/after self-admin1.11.02.01.01.4-0.81.1-0.7-0.9-0.9
Delta time in open arm before/after self-admin0.10.20.5-0.5-0.70.3-0.40.30.30.1
Diff in mean of infusions in LGA sessions0.10.20.40.60.3-0.20.4-0.6-0.7-0.4
Delay discount exponential model param0.10.10.20.3-0.2-0.4-0.2-0.3-0.3-0.0
Extinction: sum of active levers before priming0.00.00.00.1-0.10.1-0.10.1-0.00.2
Active lever presses in extinction session 60.60.61.30.61.0-1.01.1-0.3-0.5-0.6
Bone: final force3.96.36.92.42.6-2.32.5-2.6-2.6-2.5
Bone: final moment2.74.34.91.92.2-1.92.2-2.1-2.1-2.0
Food consumed during 24 hour testing period1.12.13.01.11.0-1.71.6-1.5-1.5-1.7
Glucose3.96.29.8-3.1-2.62.4-2.12.42.42.1
Heart weight1.72.84.4-1.7-1.32.1-1.11.91.81.7
Delay discount hyperbolic model param0.10.10.30.50.0-0.60.1-0.5-0.5-0.3
Intermittent access intake day 1-15 change0.21.11.41.10.9-1.20.9-1.1-1.1-0.9
Intermittent access intake escalation0.31.71.91.41.3-1.31.2-1.4-1.4-1.2
Intermittent access intake escalation 20.00.00.1-0.3-0.2-0.20.20.0-0.0-0.1
Intermitt. access day 1 inactive lever presses0.10.81.9-0.5-1.31.1-1.40.40.40.7
Intermitt. access day 15 inactive lever presses0.00.10.3-0.1-0.1-0.20.0-0.5-0.5-0.3
Intermitt. access escalation Index0.10.30.70.2-0.50.8-0.90.10.10.5
Intermittent access day 1 total infusions0.51.62.2-1.5-0.91.4-0.51.41.51.3
Intermittent access day 15 total infusions0.00.00.1-0.10.2-0.00.30.10.10.2
Intermittent access terminal intake (last 3 days)0.10.10.2-0.30.1-0.00.10.50.40.4
Intermittent access total infusions0.30.40.7-0.8-0.30.5-0.10.80.80.7
Intermittent access day 1 locomotion0.00.10.2-0.5-0.20.0-0.00.40.40.2
Intermittent access day 15 total locomotion0.41.42.60.61.2-1.61.4-1.0-1.0-1.2
Intermittent access total locomotion0.10.20.6-0.30.3-0.80.60.0-0.0-0.3
Intermittent access standard deviation0.62.93.61.61.5-1.61.6-1.9-1.9-1.7
Left kidney weight0.42.93.91.11.8-1.62.0-1.6-1.7-2.0
Right kidney weight0.64.25.61.32.0-2.12.3-2.0-2.1-2.4
Cocaine induced anxiety0.10.30.9-0.6-0.90.2-0.70.00.20.4
Post-drug Anxiety0.10.10.20.0-0.3-0.4-0.1-0.3-0.2-0.1
Baseline Anxiety1.01.62.31.51.5-1.31.3-1.1-1.1-1.2
Tail length0.52.97.1-2.7-1.91.3-1.41.51.41.1
Length with tail0.52.18.2-2.9-1.71.2-0.61.00.90.5
Length without tail0.10.71.5-0.70.3-0.51.2-0.9-0.8-1.1
Times rat made contact with spout0.10.10.40.60.4-0.10.20.00.0-0.0
Lifetime Intake0.20.20.4-0.6-0.10.30.10.60.60.5
Liver weight, left0.10.20.5-0.7-0.6-0.30.2-0.2-0.3-0.6
Liver weight, right1.11.95.5-2.4-1.90.5-1.31.01.00.6
Locomotor activity0.00.10.3-0.1-0.40.2-0.5-0.1-0.1-0.1
Locomotor testing distance0.20.61.01.00.4-0.70.3-0.9-1.0-0.8
Locomotor testing rearing0.41.42.01.10.8-1.40.9-1.3-1.4-1.3
Locomotion in novel chamber0.10.10.5-0.3-0.40.7-0.10.30.20.1
Locomotion in novel chamber post-restriction0.92.63.51.51.7-1.91.6-1.5-1.4-1.6
Fecal boli incidents, locomotor time 10.20.41.10.30.5-0.31.0-0.6-0.6-0.7
Change in fecal boli incidents, locomotor task0.10.10.50.40.2-0.70.1-0.3-0.3-0.3
Time >=10cm from walls, locomotor time 13.13.85.01.61.3-1.91.9-2.2-2.2-2.2
Bouts of movement, locomotor time 10.10.10.3-0.2-0.6-0.2-0.50.00.00.1
Total resting periods, locomotor time 10.10.10.4-0.4-0.6-0.2-0.50.10.10.1
Rest time, locomotor task time 10.91.41.9-1.4-1.10.7-1.21.31.31.4
Distance moved, locomotor task time 10.51.41.91.11.1-1.41.1-1.2-1.2-1.2
Vertical activity count, locomotor time 10.75.26.72.01.8-2.12.4-2.5-2.5-2.6
Time >=10cm from walls, locomotor time 21.33.75.31.61.9-1.92.3-1.9-1.9-2.0
Bouts of movement, locomotor time 20.10.30.8-0.7-0.8-0.5-0.90.20.20.3
Total resting periods, locomotor time 20.31.12.1-1.2-1.4-0.2-1.50.80.80.9
Rest time, locomotor task time 20.50.81.6-1.1-1.30.1-1.10.70.70.7
Distance moved, locomotor task time 22.93.85.61.72.3-1.92.4-1.7-1.7-2.0
Vertical activity count, locomotor time 21.12.64.51.31.7-1.32.1-1.5-1.5-1.7
Light reinforcement 11.04.76.12.31.8-2.01.9-2.5-2.5-2.1
Light reinforcement 21.12.53.31.21.2-1.81.5-1.8-1.8-1.7
Bone: marrow area0.20.41.0-1.0-0.5-0.40.5-0.4-0.4-0.8
Bone: maximum diameter1.22.44.0-2.0-1.81.5-1.41.41.41.2
Bone: maximum force0.51.01.30.91.1-0.61.1-1.1-1.1-0.9
Bone: maximum moment0.20.30.60.40.7-0.30.8-0.6-0.6-0.5
Mean time between licks in bursts1.48.611.4-3.2-3.42.6-3.02.82.82.5
Mean num. licks in bursts0.30.81.51.11.2-1.00.9-0.6-0.6-0.5
Cd content in liver1.31.52.31.01.3-1.11.5-1.2-1.2-1.2
Co content in liver5.46.37.02.32.6-2.32.6-2.6-2.6-2.4
Cu content in liver0.20.21.21.10.6-0.10.2-0.3-0.3-0.0
Fe content in liver0.50.70.90.70.9-0.80.7-0.9-0.9-0.7
K content in liver2.42.42.7-1.4-1.41.5-1.61.61.61.5
Mg content in liver3.03.35.0-2.0-2.21.6-2.11.51.51.6
Mn content in liver3.74.17.7-2.8-2.71.7-2.31.21.21.7
Na content in liver0.10.10.30.2-0.00.0-0.50.30.30.4
Rb content in liver0.10.10.30.10.2-0.30.5-0.4-0.4-0.3
Se content in liver8.09.411.1-3.3-3.32.9-3.12.92.92.9
Sr content in liver0.10.10.50.00.4-0.10.7-0.0-0.0-0.3
Zn content in liver1.72.02.7-1.7-1.61.5-1.31.21.31.3
Bone: minimum diameter0.10.20.7-0.8-0.60.20.00.20.2-0.2
Time in familiar zone, hab. session 10.10.10.40.50.6-0.20.2-0.2-0.20.1
Time in novel zone, hab. session 10.10.10.2-0.4-0.4-0.0-0.30.40.40.2
Total zone transitions, hab. session 11.31.82.5-0.6-1.11.5-1.61.31.31.6
Total locomotion distance, hab. session 11.72.53.9-0.9-1.41.7-2.01.51.51.8
Locomotion velocity, hab. session 11.92.73.8-1.0-1.41.9-1.91.61.61.8
Time in familiar zone, hab. session 20.10.10.30.3-0.50.0-0.4-0.3-0.3-0.2
Time in novel zone, hab. session 20.20.20.7-0.00.8-0.30.8-0.2-0.2-0.3
Total zone transitions, hab. session 20.20.30.80.0-0.50.5-0.90.30.30.6
Total locomotion distance, hab. session 20.91.22.4-0.3-1.11.2-1.60.90.91.1
Locomotion velocity, hab. session 21.52.13.8-0.7-1.51.6-1.91.31.31.5
Novel to familiar place preference ratio0.10.10.40.30.60.10.4-0.1-0.10.0
Novelty place preference0.00.00.20.10.40.20.20.10.10.2
Time in novel zone, NPP test0.00.00.10.00.40.10.20.10.10.2
Total zone transitions, NPP test1.72.53.6-1.1-1.41.6-1.91.61.61.8
Total locomotion distance, NPP test0.40.61.0-0.4-0.50.9-0.90.70.71.0
Locomotion velocity, NPP test0.50.71.1-0.2-0.61.0-1.00.70.71.0
Intraocular pressure0.10.10.30.30.5-0.40.3-0.3-0.3-0.5
Delta distance traveled before/after self-admin0.10.10.2-0.0-0.0-0.30.4-0.2-0.2-0.3
Delta ambulatory time before/after self-admin0.00.10.1-0.0-0.2-0.40.4-0.2-0.2-0.3
Parametrial fat weight4.09.411.12.82.7-3.32.9-3.1-3.1-3.3
Pavlov. Cond. lever latency7.29.110.33.12.6-3.22.8-3.2-3.2-3.1
Pavlov. Cond. magazine entry latency5.97.68.5-2.9-2.72.6-2.82.82.82.7
Pavlov. Cond. change in total contacts1.71.92.4-1.5-1.11.2-1.21.61.51.4
Pavlov. Cond. index score7.29.110.0-3.2-2.73.0-2.93.23.13.0
Pavlov. Cond. latency score6.78.69.4-3.1-2.63.0-2.83.03.02.9
Pavlov. Cond. lever contacts5.06.16.9-2.6-2.12.6-2.22.62.62.5
Pavlov. Cond. magazine entry number5.06.36.62.62.5-2.42.6-2.6-2.5-2.5
Pavlov. Cond. intertrial magazine entries1.61.92.91.51.7-1.21.5-1.3-1.3-1.0
Pavlov. Cond. lever-magazine prob. diff.7.18.910.0-3.1-2.63.0-2.83.23.13.0
Pavlov. Cond. response bias7.59.310.1-3.2-2.93.0-3.03.13.13.1
Pavlov. Cond. lever latency0.71.01.60.80.7-0.90.9-1.2-1.2-1.2
Pavlov. Cond. magazine entry latency0.10.10.4-0.6-0.2-0.00.10.20.20.1
Pavlov. Cond. change in total contacts0.10.30.6-0.5-0.40.5-0.40.70.70.7
Pavlov. Cond. index score0.40.61.0-1.0-0.60.6-0.60.90.90.8
Pavlov. Cond. latency score0.30.40.7-0.8-0.60.5-0.50.80.80.7
Pavlov. Cond. lever contacts0.40.61.0-0.6-0.50.7-0.61.01.00.9
Pavlov. Cond. magazine entry number0.10.10.3-0.0-0.30.4-0.50.30.30.4
Pavlov. Cond. intertrial magazine entries0.81.73.6-1.2-1.90.9-1.61.11.11.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.7-0.8-0.50.4-0.40.80.70.6
Pavlov. Cond. response bias0.81.11.6-1.1-0.80.9-0.91.31.21.2
Time in closed arm before self-admin0.00.10.1-0.3-0.30.4-0.00.20.20.0
Time in closed arm after self-admin0.10.10.30.20.50.50.20.50.30.1
Time in open arm before self-admin0.50.60.8-0.8-0.60.7-0.80.70.80.9
Time in open arm after self-admin0.60.71.4-1.0-1.20.6-0.80.60.60.6
Bone: periosteal estimation0.00.10.5-0.7-0.40.10.1-0.1-0.1-0.3
Bone: periosteal perimeter0.00.10.2-0.5-0.4-0.00.10.00.0-0.3
Bone: post-yield work0.30.41.1-1.0-0.81.1-0.10.40.40.2
Progressive ratio test 1 active lever presses0.00.10.1-0.20.2-0.30.40.30.20.0
Progressive ratio test 1 breakpoint0.00.10.1-0.30.1-0.10.30.30.30.1
Progressive ratio test 1 inactive lever presses0.61.52.21.21.3-1.51.1-1.1-1.1-1.1
Progressive ratio test 2 active lever presses0.10.10.2-0.10.1-0.30.00.40.30.3
Progressive ratio test 2 breakpoint0.10.10.2-0.10.1-0.20.00.50.40.3
Progressive ratio test 2 inactive lever presses0.30.81.4-1.1-0.80.4-0.61.11.20.8
Incentive Sensitization - Responses0.20.50.6-0.5-0.70.6-0.80.80.60.7
Incentive Sensitization - Breakpoint0.10.20.3-0.3-0.50.3-0.60.50.40.6
Sum of active levers in priming session hrs 5-60.20.20.3-0.4-0.30.6-0.30.50.40.4
Progressive ratio1.64.98.72.02.0-3.01.9-2.1-2.1-2.2
Food seeking constrained by brief footshock0.20.30.80.40.8-0.10.9-0.1-0.2-0.5
Seeking ratio, punishment vs. effort1.43.16.7-1.4-1.32.6-1.31.81.71.8
Retroperitoneal fat weight0.31.32.21.01.3-1.51.0-0.9-0.9-1.2
Reaction time number correct0.93.34.62.12.0-2.11.6-1.6-1.5-1.7
Reaction time mean minus median0.42.85.9-2.4-2.11.6-1.41.31.31.2
Reaction time mean minus median AUC0.42.55.6-2.4-1.71.5-1.01.61.51.1
Reaction time num false alarms0.71.11.6-1.0-1.31.0-1.21.01.00.8
Reaction time num false alarms AUC0.92.02.8-1.3-1.71.5-1.51.41.41.2
Reaction time trials correct on left0.93.34.62.12.0-2.11.6-1.6-1.5-1.7
Reaction time trials on left1.03.34.42.12.0-2.01.6-1.6-1.5-1.8
Reaction time mean0.40.82.6-1.6-1.21.0-0.30.50.40.3
Reaction time mean AUC0.20.52.0-1.4-0.90.7-0.10.40.30.1
Median of all reaction times0.10.20.8-0.9-0.50.50.20.1-0.0-0.2
Reaction time omissions0.20.41.2-1.0-1.10.3-0.60.30.20.0
Reaction time false alarm rate4.25.87.1-2.5-2.72.5-2.42.32.22.2
Reaction time premature initiation rate0.10.10.30.20.1-0.10.3-0.6-0.6-0.3
Reaction time premature initiations0.72.22.61.51.4-1.41.4-1.6-1.6-1.5
Std. dev. reaction times1.03.37.2-2.7-2.31.8-1.41.51.31.2
Reaction time trials completed1.03.34.42.12.0-2.01.6-1.6-1.5-1.8
Reaction time trials AUC1.03.44.62.12.0-2.11.6-1.6-1.6-1.8
Run reversals in cocaine runway, females0.20.20.60.20.7-0.10.80.0-0.1-0.1
Run reversals in cocaine runway, males2.32.54.0-1.9-1.52.0-1.41.51.41.3
Latency to leave start box in cocaine runway0.20.30.8-0.3-0.40.9-0.50.40.40.6
Latency to leave start box in cocaine runway, F0.10.10.3-0.2-0.30.4-0.30.20.20.5
Latency to leave start box in cocaine runway, M0.10.10.3-0.0-0.10.6-0.20.20.20.2
Std. dev. time between licks in bursts3.56.57.9-2.8-2.72.2-2.82.52.52.2
Total sessions with >9 infusions0.10.10.3-0.6-0.30.4-0.00.40.40.3
Short access day 1 total inactive lever presses0.61.11.9-1.4-0.91.0-0.51.31.30.8
Short access day 10 total inactive lever presses0.00.30.50.6-0.4-0.2-0.7-0.6-0.6-0.1
Short access day 1 total infusions0.40.71.2-1.1-0.80.7-0.41.01.00.7
Short access day 10 total infusions0.00.00.1-0.10.00.10.3-0.1-0.1-0.1
Short access total infusions0.10.10.2-0.5-0.10.30.20.40.40.3
Short access day 1 locomotion0.10.20.5-0.3-0.60.2-0.70.30.30.5
Short access day 10 total locomotion0.00.20.7-0.5-0.8-0.1-0.60.10.10.1
Short access total locomotion0.00.00.1-0.2-0.30.0-0.1-0.1-0.1-0.1
One hour access (0.3 mA shock)1.62.02.5-1.2-1.51.4-1.51.31.31.6
Compulsive drug intake0.50.82.0-0.6-1.41.4-0.90.20.10.7
One hour access (shock baseline)0.20.51.2-0.8-0.30.2-0.41.11.10.7
Social response proportion0.10.10.3-0.5-0.50.4-0.20.20.20.2
Social responses0.00.00.2-0.1-0.50.1-0.30.10.00.0
Social time1.11.84.4-1.4-2.11.3-1.60.70.70.9
Soleus weight3.08.814.8-3.8-3.32.8-2.62.82.82.3
Bone: stiffness0.91.62.21.31.1-1.01.1-1.5-1.5-1.2
Tibialis anterior weight0.00.10.20.1-0.40.4-0.3-0.1-0.10.2
Time to tail flick, vehicle, before self-admin0.50.62.10.80.4-1.4-0.1-0.7-0.7-0.7
Time to tail flick, vehicle, after self-admin0.10.10.4-0.5-0.60.5-0.20.10.20.3
Time to tail flick, test, before self-admin0.10.10.50.3-0.1-0.1-0.7-0.0-0.00.2
Time to tail flick, test, after self-admin0.80.91.4-0.9-0.80.0-1.21.11.01.1
Delta time to tail flick, vehicle, before/after SA0.30.31.2-0.5-0.11.10.30.40.50.6
Delta time to tail flick, test, before/after SA0.10.20.60.30.5-0.70.4-0.1-0.1-0.2
Tibia length0.10.40.7-0.4-0.1-0.60.4-0.7-0.9-0.8
Ambulatory time before self-admin0.00.10.10.10.0-0.1-0.1-0.3-0.3-0.4
Ambulatory time after self-admin0.10.20.60.2-0.1-0.50.3-0.6-0.6-0.8
Bone: tissue strength0.50.51.00.50.9-0.61.0-0.6-0.6-0.7
Total heroin consumption0.10.10.30.2-0.40.5-0.2-0.3-0.4-0.1
Bone: trabecular number0.00.00.10.2-0.00.3-0.0-0.1-0.10.3
Bone: trabecular spacing0.40.61.00.40.7-1.00.9-0.7-0.7-1.0
Bone: trabecular thickness0.20.20.30.30.5-0.30.4-0.6-0.6-0.3
Bone: trabecular tissue density0.61.01.4-1.2-0.81.0-0.91.01.01.0
Water consumed over 24 hours0.00.10.2-0.2-0.50.1-0.20.20.20.1
Number of responses in last shaping day3.14.15.2-2.2-1.81.9-1.52.32.22.1