Hub : Genes

Tap2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Tap2 0.17 0.07 3.3e-13 0.12 0.14 0.14 0.14 1.2e-09 3.9e-11 1.5e-11 3.8e-11
2 Eye mRNA stability Tap2 0.74 0.14 8.2e-06 0.08 0.13 0.06 0.08 2.5e-02 5.1e-03 5.2e-02 2.5e-02
3 IC gene expression Tap2 0.38 0.12 8.3e-16 0.2 0.28 0.25 0.25 6.8e-09 3.8e-12 6.6e-11 6.0e-11
4 NAcc mRNA stability Tap2 0.28 0.08 0.0e+00 0.31 0.34 0.35 0.35 8.5e-48 3.1e-54 1.1e-55 5.8e-55
5 Brain gene expression Tap2 0.21 0.07 0.0e+00 0.17 0.2 0.18 0.18 1.7e-15 1.8e-18 8.0e-17 8.4e-17
6 PL gene expression Tap2 0.12 0.05 2.8e-16 0.15 0.16 0.14 0.14 1.2e-15 7.1e-17 3.6e-15 1.8e-15
7 NAcc gene expression Tap2 0.07 0.04 3.2e-11 0.07 0.06 0.06 0.06 1.0e-10 6.8e-09 5.8e-09 3.8e-09
8 LHb mRNA stability Tap2 0.54 0.14 1.4e-11 0.39 0.36 0.41 0.41 2.3e-10 1.4e-09 6.3e-11 8.0e-11
9 BLA mRNA stability Tap2 0.49 0.11 0.0e+00 0.4 0.49 0.5 0.49 7.7e-23 1.5e-29 1.3e-29 1.8e-29
10 pVTA mRNA stability Tap2 0.45 0.11 0.0e+00 0.42 0.41 0.42 0.43 4.2e-36 1.0e-35 7.3e-37 1.4e-37
11 IL mRNA stability Tap2 0.43 0.14 4.3e-09 0.28 0.22 0.29 0.29 1.8e-07 5.8e-06 9.8e-08 9.3e-08
12 Liver gene expression Tap2 0.27 0.09 0.0e+00 0.32 0.31 0.31 0.31 6.9e-36 6.0e-35 2.7e-35 4.1e-35
13 Brain mRNA stability Tap2 0.65 0.08 0.0e+00 0.63 0.65 0.66 0.66 1.5e-74 1.5e-79 1.5e-80 4.8e-81
14 Liver mRNA stability Tap2 0.38 0.09 0.0e+00 0.5 0.5 0.51 0.51 1.2e-62 2.6e-64 4.6e-65 1.2e-65
15 Adipose gene expression Tap2 0.61 0.1 0.0e+00 0.51 0.54 0.54 0.54 3.6e-65 1.4e-70 1.7e-70 5.2e-71
16 PL mRNA stability Tap2 0.48 0.1 0.0e+00 0.52 0.53 0.6 0.6 2.4e-66 2.2e-68 3.2e-81 7.9e-82
17 RMTg gene expression Tap2 0.18 0.1 1.9e-03 0.1 0.13 0.09 0.1 1.2e-03 2.5e-04 2.4e-03 1.4e-03
18 Adipose mRNA stability Tap2 0.63 0.09 0.0e+00 0.69 0.72 0.72 0.73 1.3e-106 5.4e-114 4.4e-116 7.7e-117
19 OFC mRNA stability Tap2 0.51 0.13 1.3e-11 0.26 0.35 0.4 0.41 8.2e-07 3.3e-09 1.2e-10 5.9e-11
20 IC mRNA stability Tap2 0.47 0.13 0.0e+00 0.26 0.37 0.37 0.35 1.5e-11 2.5e-16 1.4e-16 1.6e-15
21 BLA gene expression Tap2 0.53 0.14 0.0e+00 0.42 0.47 0.48 0.48 3.6e-24 1.7e-27 1.1e-28 3.5e-28
22 OFC gene expression Tap2 0.42 0.14 1.9e-06 0.03 0.04 0.11 0.07 5.5e-02 5.0e-02 1.4e-03 8.1e-03
23 Liver intron excision ratio chr20_4650951_4651037 0.07 0.04 5.3e-03 0.01 -0 -0 -0 1.4e-02 6.0e-01 5.1e-01 7.0e-01
24 Liver intron excision ratio chr20_4651537_4652216 0.07 0.04 6.0e-03 0.01 -0 0 -0 1.9e-02 5.2e-01 3.7e-01 8.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.62.96.22.4-1.7-1.81.80.0-1.21.12.11.6-1.9-2.0-2.5-1.8-1.82.5-1.72.3-1.3-1.31.71.5-0.7-0.80.8
Area under the delay curve0.20.30.8-0.70.90.8-0.30.20.6-0.6-0.8-0.10.40.80.30.70.7-0.60.7-0.50.30.5-0.3-0.60.20.5-0.5
BMI with tail1.13.78.2-0.91.61.7-2.52.21.6-2.4-1.8-2.92.11.91.42.22.3-1.02.3-1.22.52.7-2.3-2.0-0.3-0.60.6
BMI without tail1.26.59.0-2.63.03.0-2.82.42.9-3.0-2.8-2.82.72.82.52.93.0-2.22.9-2.22.72.8-2.7-2.3-0.4-0.10.1
Body weight3.013.118.7-3.43.43.8-4.21.92.9-3.6-4.3-4.34.04.23.94.34.3-3.94.2-3.93.84.1-4.2-3.41.30.1-0.1
Weight adjusted by age1.02.85.9-1.91.41.6-1.70.00.9-1.1-2.2-1.41.81.92.11.81.7-2.41.8-1.91.31.6-2.0-1.61.41.6-1.6
Bone surface0.10.31.20.3-0.5-0.30.2-0.6-0.40.40.30.3-0.3-0.1-0.5-0.2-0.40.2-0.2-0.2-0.5-0.20.10.61.0-1.11.1
Bone volume0.20.31.20.9-0.5-0.50.50.1-0.30.30.70.5-0.6-0.5-1.1-0.4-0.50.9-0.40.6-0.4-0.30.50.50.2-0.80.8
Breakpoint value in progressive ratio session0.10.31.10.2-0.5-0.40.4-0.5-0.40.60.50.5-0.4-0.4-0.2-0.5-0.60.3-0.50.1-0.5-0.60.50.40.0-1.11.1
Number of licking bursts0.20.62.50.1-0.9-0.60.4-1.6-1.01.00.50.3-0.5-0.4-0.2-0.4-0.6-0.0-0.6-0.5-0.9-0.80.61.00.8-1.11.1
Context. condit. distance diff. score6.17.412.53.2-3.5-3.32.9-3.3-3.53.32.82.6-3.0-2.8-2.7-2.7-2.92.3-2.81.6-3.0-2.82.52.70.9-0.40.4
Locomotion velocity, session 11.41.63.20.6-1.1-1.21.6-1.4-1.21.71.21.8-1.3-1.3-1.0-1.4-1.50.8-1.50.9-1.5-1.61.41.30.00.9-0.9
Locomotion distance, session 11.41.83.11.8-1.3-1.51.4-0.2-1.01.11.71.2-1.5-1.6-1.6-1.4-1.41.7-1.41.6-1.1-1.21.41.1-1.6-0.60.6
Locomotion velocity, session 20.40.50.90.6-0.7-0.60.8-0.8-0.60.80.80.7-0.9-0.6-0.7-0.7-0.80.6-0.70.2-0.8-0.80.91.0-0.1-0.70.7
Locomotion distance, session 21.11.53.41.8-1.6-1.61.1-0.8-1.51.21.40.9-1.4-1.4-1.2-1.3-1.21.4-1.31.3-1.0-1.01.21.2-0.50.1-0.1
Locomotion velocity, session 30.20.31.2-0.50.70.6-0.21.00.9-0.60.1-0.40.10.30.30.20.30.30.20.20.20.1-0.1-0.5-1.1-0.60.6
Locomotion distance, session 31.82.13.41.7-1.4-1.51.7-0.4-1.11.31.81.3-1.7-1.7-1.4-1.7-1.51.8-1.71.7-1.4-1.51.61.0-1.3-0.40.4
Stereotopy head waving bouts, day 31.31.64.3-1.90.91.2-1.3-0.40.6-0.6-1.5-1.11.41.42.11.31.1-1.91.2-1.90.70.9-1.3-0.61.5-0.10.1
Stereotopy head waving duration, day 31.21.54.5-2.11.31.4-1.2-0.10.9-0.7-1.4-0.91.31.41.91.21.1-1.71.1-1.60.70.8-1.1-0.61.10.6-0.6
Locomotion velocity, session 75.25.712.83.6-2.9-3.02.4-1.3-2.82.22.82.1-2.7-2.7-2.7-2.6-2.52.9-2.52.8-1.9-2.02.21.7-0.50.8-0.8
Locomotion distance, session 75.97.611.63.4-2.9-3.23.1-1.4-2.72.63.22.8-3.1-3.2-2.8-3.2-2.93.2-3.13.3-2.7-2.82.92.3-1.20.9-0.9
Stereotopy head waving bouts, day 70.30.42.1-1.41.31.0-0.20.41.1-0.5-0.50.10.30.50.50.40.4-0.40.3-0.50.20.10.10.0-0.80.1-0.1
Stereotopy head waving duration, day 70.70.93.5-1.91.41.3-0.80.61.3-0.9-1.0-0.60.91.01.20.90.9-0.90.8-0.90.70.6-0.6-0.5-0.2-0.10.1
Locomotion velocity, session 81.31.57.70.4-1.5-1.21.2-2.8-1.92.00.71.2-1.1-0.7-0.5-0.8-1.20.1-1.0-0.5-1.5-1.40.81.41.4-0.10.1
Locomotion distance, session 85.58.115.73.8-4.0-3.62.8-3.1-3.93.43.02.4-3.1-3.0-2.7-2.8-3.02.6-2.91.9-2.8-2.72.52.60.7-0.60.6
Degree of sensitization distance0.30.32.00.2-0.7-0.50.2-1.2-0.90.80.10.3-0.1-0.2-0.2-0.3-0.4-0.3-0.3-0.3-0.4-0.5-0.00.41.40.2-0.2
Degree of sensitization stereotypy0.30.31.6-0.40.50.20.60.20.50.10.50.7-0.6-0.3-0.6-0.4-0.30.6-0.50.4-0.5-0.61.00.6-1.3-0.20.2
Conditioned locomotion0.70.82.2-0.60.20.6-1.1-0.20.2-0.6-0.8-1.20.91.00.61.00.8-0.91.0-1.30.70.9-1.1-0.61.5-1.11.1
Cocaine response after cond. corrected0.20.41.61.3-1.2-0.9-0.1-0.6-1.20.50.4-0.4-0.3-0.4-0.3-0.2-0.30.3-0.20.1-0.00.1-0.10.20.7-0.80.8
Cocaine response after cond. not corrected0.40.51.7-0.4-0.10.3-0.9-0.7-0.2-0.1-0.7-1.00.70.70.80.70.5-1.00.7-1.30.50.6-0.9-0.31.2-0.90.9
Cocaine response before conditioning3.64.312.9-3.62.62.7-1.80.52.3-1.6-2.5-1.52.32.42.62.22.0-2.71.9-2.81.41.3-1.9-1.50.9-0.30.3
Saline control response3.85.210.5-2.63.22.9-2.23.03.2-2.9-2.3-1.92.52.22.02.32.6-1.62.3-1.12.52.3-2.1-2.0-0.70.9-0.9
Bone: connectivity density1.32.04.62.1-1.8-1.71.4-0.5-1.51.11.71.3-1.5-1.6-2.0-1.4-1.51.7-1.41.6-1.1-1.01.21.40.2-0.90.9
Bone: cortical apparent density1.21.94.3-0.81.51.5-1.52.11.7-1.9-1.2-1.61.31.31.21.41.6-0.71.5-0.61.71.8-1.4-1.4-0.3-0.50.5
Bone: cortical area0.10.20.5-0.50.50.6-0.40.10.4-0.5-0.5-0.40.30.70.10.60.5-0.30.7-0.70.30.5-0.4-0.40.20.1-0.1
Bone: cortical porosity0.50.51.5-1.00.90.50.8-0.10.70.20.01.2-0.5-0.00.1-0.3-0.20.0-0.30.2-0.7-0.70.90.3-1.21.2-1.2
Bone: cortical porosity0.50.52.2-1.10.60.30.9-0.60.30.6-0.01.3-0.5-0.10.1-0.4-0.4-0.3-0.4-0.0-0.9-0.90.90.5-0.51.5-1.5
Bone: cortical thickness0.61.03.9-0.21.31.1-0.82.01.6-1.5-0.4-0.90.50.8-0.00.91.00.31.00.11.01.1-0.5-1.1-1.4-0.40.4
Bone: cortical thickness1.82.26.1-1.01.71.6-1.62.52.1-2.1-1.0-1.81.31.30.81.51.7-0.31.5-0.41.81.7-1.3-1.7-0.7-0.90.9
Bone: cortical tissue density1.11.83.8-0.81.51.4-1.52.01.7-1.8-1.2-1.51.31.31.21.41.6-0.81.5-0.61.71.7-1.4-1.4-0.2-0.50.5
Condit. Reinf. active minus inactive responses0.50.61.40.0-0.2-0.51.0-0.3-0.20.70.51.2-0.5-0.8-0.6-1.0-0.80.4-1.00.8-0.8-1.10.80.60.21.0-1.0
Condit. Reinf. active-inactive response ratio0.40.41.2-1.11.10.9-0.40.91.1-0.7-0.7-0.30.80.50.60.40.6-0.60.5-0.20.60.3-0.5-0.80.00.5-0.5
Condit. Reinf. active responses0.50.71.40.7-0.6-0.81.1-0.1-0.50.70.71.1-0.6-1.1-0.8-1.2-0.90.8-1.21.2-0.7-1.10.80.40.10.7-0.7
Condit. Reinf. inactive responses1.41.94.32.1-1.4-1.61.50.1-1.10.91.61.2-1.4-1.7-1.6-1.7-1.31.9-1.62.0-1.0-1.21.30.6-0.9-0.10.1
Incentive salience index mean1.82.43.51.5-1.7-1.71.8-1.6-1.71.81.51.8-1.6-1.6-1.6-1.7-1.71.2-1.71.1-1.8-1.91.61.50.70.5-0.5
Condit. Reinf. lever presses3.65.410.33.0-3.2-2.92.3-2.8-3.22.72.32.1-2.5-2.3-2.2-2.3-2.41.9-2.31.3-2.5-2.32.12.31.0-0.40.4
Condit. Reinf. active minus inactive responses0.50.82.2-1.51.21.1-0.60.20.9-0.7-1.1-0.50.91.01.00.90.8-1.10.7-1.00.50.4-0.8-1.10.70.5-0.5
Condit. Reinf. active-inactive response ratio0.61.02.5-1.61.01.0-0.6-0.40.6-0.4-1.3-0.51.01.11.30.90.8-1.60.7-1.40.50.4-1.0-0.91.40.9-0.9
Condit. Reinf. active responses0.10.20.7-0.80.60.6-0.20.30.6-0.3-0.4-0.10.40.40.50.20.3-0.40.2-0.30.20.0-0.4-0.60.30.2-0.2
Condit. Reinf. inactive responses0.10.21.0-0.20.40.3-0.31.00.7-0.5-0.0-0.40.10.1-0.00.20.30.30.20.20.40.3-0.1-0.3-0.8-0.60.6
Condit. Reinf. lever presses0.60.81.70.4-0.3-0.61.3-0.2-0.30.70.91.2-1.0-1.0-0.9-1.1-0.91.0-1.11.1-1.1-1.21.10.4-0.70.8-0.8
Condit. Reinf. lever reinforcers received0.10.10.7-0.80.50.40.10.10.5-0.1-0.30.10.20.20.30.00.1-0.3-0.1-0.2-0.0-0.2-0.1-0.50.20.2-0.2
Conditioned reinforcement - actives0.00.10.30.4-0.1-0.20.30.3-0.1-0.00.10.3-0.2-0.3-0.2-0.3-0.10.3-0.20.6-0.10.00.2-0.1-0.20.5-0.5
Conditioned reinforcement - inactives0.00.10.7-0.30.1-0.1-0.10.2-0.00.0-0.20.20.1-0.20.3-0.2-0.0-0.2-0.10.40.10.10.2-0.1-0.20.8-0.8
Conditioned locomotion0.20.31.10.2-0.4-0.50.5-0.5-0.60.40.20.7-0.5-0.4-0.3-0.4-0.40.1-0.40.5-0.5-0.30.20.30.71.0-1.0
Patch foraging indifference point 0 sec1.54.16.8-2.22.62.4-2.12.32.5-2.4-2.2-1.82.22.02.32.02.2-1.92.0-1.22.52.1-1.9-2.0-0.10.5-0.5
Patch foraging indifference point AUC0.20.51.8-1.30.91.0-0.40.20.9-0.5-0.7-0.30.70.71.10.50.4-0.90.5-0.90.20.1-0.50.00.4-0.70.7
Delay disc. indifference point, 0s delay0.20.21.00.3-0.4-0.30.2-0.8-0.60.4-0.10.3-0.3-0.0-0.10.1-0.0-0.2-0.0-0.3-0.2-0.00.00.20.61.0-1.0
Delay disc. indifference point, 16s delay0.10.20.7-0.40.80.5-0.20.90.8-0.7-0.3-0.10.10.4-0.30.30.50.20.40.30.20.40.1-0.5-0.70.2-0.2
Delay disc. indifference point, 2s delay0.50.52.1-1.00.70.7-0.1-0.70.2-0.2-1.00.10.50.81.00.60.5-1.40.5-1.00.20.2-0.4-0.31.40.7-0.7
Delay disc. indifference point, 24s delay0.50.82.5-1.61.51.2-0.50.61.2-0.8-1.2-0.30.80.90.70.81.0-1.00.8-0.50.60.6-0.5-0.9-0.21.0-1.0
Delay disc. indifference point, 4s delay1.51.62.6-1.61.51.6-1.20.51.3-1.2-1.6-1.01.31.61.41.51.4-1.51.4-1.51.01.2-1.2-0.80.80.0-0.0
Delay disc. indifference point, 8s delay0.10.10.8-0.10.50.30.20.00.2-0.2-0.40.2-0.00.4-0.20.30.3-0.20.3-0.0-0.00.20.0-0.4-0.30.9-0.9
Indifference point function ln k0.10.30.90.1-0.6-0.50.5-1.0-0.70.80.60.6-0.6-0.4-0.7-0.5-0.60.3-0.60.0-0.8-0.80.70.60.6-0.10.1
Indifference point function log k0.10.30.90.1-0.6-0.50.5-1.0-0.70.80.60.6-0.6-0.4-0.7-0.5-0.60.3-0.60.0-0.8-0.80.70.60.6-0.10.1
Patch foraging total patch changes 0 sec1.44.17.0-2.22.72.4-2.12.42.6-2.5-2.1-1.92.12.02.32.02.2-1.92.0-1.22.52.1-1.9-1.9-0.30.6-0.6
Patch foraging total patch changes 12 sec2.02.74.9-2.12.22.0-1.71.92.2-2.0-1.7-1.41.91.71.91.61.6-1.61.5-1.11.71.6-1.7-1.20.2-0.20.2
Patch foraging total patch changes 18 sec0.92.27.0-0.71.71.5-1.72.62.0-2.1-1.1-1.71.31.21.51.31.6-0.61.5-0.22.01.8-1.2-1.2-1.4-0.40.4
Patch foraging total patch changes 24 sec0.10.53.10.40.60.20.11.80.9-1.00.2-0.0-0.0-0.2-0.1-0.20.10.60.01.10.60.40.2-0.1-1.60.4-0.4
Patch foraging total patch changes 6 sec1.62.75.2-1.72.32.0-1.62.22.2-2.2-1.7-1.31.81.51.61.51.7-1.41.6-0.72.01.8-1.5-1.3-0.61.0-1.0
Patch foraging time to switch 0 sec0.10.41.31.0-0.3-0.1-0.70.9-0.1-0.6-0.1-1.20.30.1-0.10.40.60.30.70.20.91.1-0.6-1.1-0.7-0.10.1
Patch foraging water rate 0 sec0.20.61.6-1.10.80.8-0.90.20.6-0.6-1.0-0.70.90.81.30.80.8-1.10.7-0.80.90.7-0.8-0.20.60.6-0.6
Patch foraging water rate 12 sec0.00.21.00.50.1-0.00.00.80.4-0.20.50.1-0.4-0.3-0.1-0.2-0.10.7-0.10.70.2-0.00.50.3-1.0-0.60.6
Patch foraging water rate 18 sec0.20.51.0-0.80.90.8-0.70.80.8-1.0-0.7-0.80.70.80.50.80.9-0.60.7-0.40.90.8-0.6-0.7-0.10.1-0.1
Patch foraging water rate 24 sec0.20.20.7-0.30.50.5-0.50.80.7-0.7-0.2-0.60.40.30.40.40.5-0.10.3-0.10.70.4-0.3-0.7-0.3-0.30.3
Patch foraging water rate 6 sec0.20.30.6-0.30.50.5-0.70.80.6-0.6-0.2-0.70.40.40.70.50.5-0.20.5-0.20.60.5-0.5-0.5-0.3-0.50.5
Seeking ratio, delayed vs. immediate footshock2.23.15.9-2.22.22.3-1.41.52.4-1.6-1.7-1.51.81.82.21.81.5-1.61.8-1.81.51.4-1.6-1.5-0.8-1.71.7
Distance traveled before self-admin0.10.20.60.4-0.4-0.0-0.4-0.3-0.3-0.0-0.2-0.7-0.00.30.40.50.2-0.40.5-0.80.40.6-0.5-0.20.2-0.80.8
Distance traveled after self-admin1.42.44.1-1.91.51.8-1.70.71.5-1.3-1.6-1.81.61.81.81.81.6-1.81.7-2.01.21.4-1.6-1.10.9-1.21.2
Extensor digitorum longus weight0.10.21.40.5-0.7-0.50.3-1.2-0.90.60.20.3-0.4-0.20.2-0.1-0.3-0.0-0.2-0.3-0.7-0.30.20.60.70.1-0.1
Bone: elastic displacement0.20.31.5-0.00.60.20.50.80.6-0.30.10.6-0.1-0.1-0.5-0.2-0.10.3-0.20.70.0-0.10.4-0.2-1.11.2-1.2
Bone: elastic work0.20.20.6-0.30.70.5-0.20.50.6-0.6-0.50.00.30.50.00.50.4-0.20.5-0.20.40.5-0.3-0.4-0.20.8-0.8
Bone: endosteal estimation1.43.510.9-2.60.91.5-1.7-1.60.2-0.4-2.3-1.51.92.12.41.81.5-3.11.7-3.30.91.2-1.9-0.93.30.6-0.6
Bone: endosteal perimeter0.41.06.9-0.7-0.7-0.1-0.3-2.4-1.10.9-0.6-0.30.30.60.70.4-0.0-1.40.4-1.9-0.4-0.1-0.60.12.60.1-0.1
Epididymis fat weight1.68.130.9-0.32.72.3-3.15.63.4-4.3-1.6-3.62.61.91.02.43.10.02.90.44.03.9-2.4-3.3-3.3-0.90.9
Delta time in closed arm before/after self-admin0.40.41.5-0.00.10.2-0.5-0.2-0.1-0.2-0.6-0.50.60.50.60.50.4-0.70.6-0.60.50.7-0.9-0.80.71.2-1.2
Delta time in open arm before/after self-admin0.00.10.30.00.30.10.00.50.4-0.30.20.1-0.1-0.1-0.1-0.10.10.3-0.10.4-0.1-0.10.20.2-0.10.3-0.3
Diff in mean of infusions in LGA sessions1.22.24.22.0-2.0-1.91.4-1.1-1.81.51.81.1-1.6-1.6-1.8-1.6-1.51.7-1.61.3-1.3-1.41.41.0-0.1-0.30.3
Delay discount exponential model param0.30.41.00.9-1.0-0.90.4-0.2-0.70.60.90.2-0.5-0.9-0.4-0.7-0.80.7-0.70.6-0.3-0.50.30.6-0.2-0.40.4
Extinction: sum of active levers before priming0.20.41.50.2-0.9-0.70.5-1.2-1.00.90.20.6-0.4-0.4-0.0-0.5-0.6-0.1-0.5-0.1-0.5-0.60.20.81.0-0.20.2
Active lever presses in extinction session 60.40.41.30.8-0.4-0.60.80.1-0.50.30.50.8-0.7-0.7-0.6-0.7-0.50.6-0.61.1-0.3-0.40.7-0.0-0.51.2-1.2
Bone: final force2.23.65.9-1.61.81.9-2.31.71.7-2.2-2.1-2.42.12.01.62.12.2-1.62.2-1.62.42.3-2.2-2.10.5-0.30.3
Bone: final moment1.62.64.2-1.31.61.6-1.91.41.5-1.9-1.8-2.01.81.71.41.81.9-1.31.8-1.32.02.0-1.8-1.80.30.2-0.2
Food consumed during 24 hour testing period0.40.72.0-0.3-0.00.4-1.1-0.4-0.2-0.4-0.9-1.30.90.80.91.00.8-1.21.0-1.30.80.9-1.0-0.51.4-0.30.3
Glucose1.82.914.10.3-2.0-1.61.4-3.7-2.62.50.51.5-1.1-1.10.3-1.3-1.5-0.7-1.5-0.5-1.9-1.90.81.52.11.7-1.7
Heart weight1.62.66.0-2.41.91.9-1.10.31.4-1.3-2.1-0.91.71.91.61.71.6-2.21.6-1.71.11.2-1.6-1.20.91.8-1.8
Delay discount hyperbolic model param0.30.51.20.9-1.1-1.00.3-0.2-0.80.60.90.1-0.5-1.0-0.5-0.8-0.80.8-0.80.7-0.3-0.50.30.6-0.3-0.40.4
Intermittent access intake day 1-15 change0.00.21.0-1.00.60.6-0.60.40.7-0.5-0.4-0.50.60.40.40.40.4-0.50.4-0.50.40.3-0.2-0.0-0.2-0.50.5
Intermittent access intake escalation0.10.72.0-1.31.31.1-0.71.31.4-1.1-0.6-0.70.80.60.50.60.8-0.40.6-0.30.80.6-0.4-0.5-1.0-0.40.4
Intermittent access intake escalation 20.00.10.6-0.80.30.2-0.1-0.10.2-0.0-0.0-0.00.10.1-0.20.00.1-0.2-0.0-0.2-0.2-0.20.10.5-0.3-0.30.3
Intermitt. access day 1 inactive lever presses0.10.62.8-0.4-0.9-0.4-0.5-1.5-1.00.7-0.1-0.50.40.10.80.1-0.2-0.80.0-1.1-0.1-0.1-0.10.61.3-1.71.7
Intermitt. access day 15 inactive lever presses0.10.51.1-0.90.50.6-0.70.10.3-0.5-0.8-0.60.80.71.10.70.5-1.00.7-0.80.70.8-0.7-0.50.20.6-0.6
Intermitt. access escalation Index0.61.93.61.9-1.8-1.51.2-1.2-1.61.61.60.9-1.2-1.4-1.3-1.3-1.51.3-1.30.6-1.1-1.31.21.3-0.1-1.91.9
Intermittent access day 1 total infusions1.13.25.51.8-1.6-2.02.2-1.0-1.71.61.62.3-1.9-2.1-1.7-2.0-1.81.6-2.02.3-1.7-1.71.81.2-0.12.0-2.0
Intermittent access day 15 total infusions0.20.41.40.30.0-0.40.70.40.00.10.50.9-0.5-0.8-0.6-0.8-0.50.6-0.71.2-0.4-0.50.70.2-0.60.9-0.9
Intermittent access terminal intake (last 3 days)0.20.31.5-0.20.3-0.10.60.30.10.10.10.9-0.4-0.5-0.1-0.6-0.30.2-0.50.9-0.3-0.40.60.3-0.41.2-1.2
Intermittent access total infusions0.60.72.00.6-0.3-0.71.10.0-0.40.50.61.3-0.8-1.0-0.7-1.0-0.80.7-0.91.4-0.7-0.80.90.4-0.41.4-1.4
Intermittent access day 1 locomotion0.30.51.91.0-0.5-0.70.70.1-0.50.40.60.8-0.8-0.7-0.5-0.7-0.50.7-0.61.1-0.3-0.30.5-0.0-0.21.4-1.4
Intermittent access day 15 total locomotion0.20.81.4-0.91.01.0-0.80.70.9-1.1-1.1-0.80.91.00.91.11.1-0.91.1-0.70.91.1-1.2-1.00.30.4-0.4
Intermittent access total locomotion0.20.21.3-0.10.60.3-0.10.70.5-0.7-0.3-0.10.10.20.00.20.5-0.00.30.30.40.5-0.3-0.5-0.21.1-1.1
Intermittent access standard deviation0.63.14.3-2.12.01.9-2.01.72.0-2.0-1.9-1.81.91.71.91.71.9-1.61.8-1.22.11.9-1.6-1.60.10.9-0.9
Left kidney weight1.411.417.0-3.03.73.9-3.82.73.5-3.9-3.7-3.93.64.03.34.04.1-3.13.9-3.23.53.7-3.6-3.50.0-0.10.1
Right kidney weight1.610.916.6-2.63.23.5-3.82.43.0-3.6-3.7-4.13.43.83.43.93.9-3.13.9-3.23.53.8-3.7-3.60.2-0.90.9
Cocaine induced anxiety0.10.43.70.3-0.6-0.3-0.3-0.6-0.50.30.2-0.30.0-0.00.20.1-0.1-0.1-0.0-0.5-0.0-0.0-0.20.30.2-1.91.9
Post-drug Anxiety0.20.30.7-0.30.10.4-0.6-0.00.2-0.2-0.4-0.70.60.50.60.60.5-0.50.6-0.90.50.5-0.7-0.30.1-0.70.7
Baseline Anxiety0.30.53.0-0.80.70.6-0.30.30.5-0.5-0.7-0.30.50.50.40.50.6-0.50.6-0.30.50.6-0.5-0.30.61.7-1.7
Tail length1.36.916.5-4.12.83.1-2.3-0.32.1-1.6-3.6-1.92.63.23.72.92.7-4.02.6-3.91.71.8-2.5-1.51.90.7-0.7
Length with tail2.310.021.4-4.02.93.4-3.1-0.32.0-2.1-4.2-2.83.33.84.13.63.4-4.63.3-4.52.52.6-3.4-2.42.81.2-1.2
Length without tail1.47.412.6-2.21.62.3-3.30.11.0-2.1-3.3-3.33.03.23.03.33.1-3.53.2-3.52.73.1-3.4-2.42.90.2-0.2
Times rat made contact with spout0.50.53.20.20.60.10.61.40.9-0.40.60.6-0.5-0.6-0.6-0.5-0.21.1-0.41.3-0.1-0.30.90.1-1.80.5-0.5
Lifetime Intake0.40.62.00.5-0.2-0.61.00.0-0.30.40.41.2-0.7-0.8-0.3-0.8-0.60.5-0.71.2-0.5-0.60.80.2-0.31.4-1.4
Liver weight, left0.91.65.5-1.40.30.9-1.4-1.2-0.0-0.3-1.5-1.51.21.31.81.31.1-2.21.2-2.40.70.7-1.6-0.71.4-0.80.8
Liver weight, right0.81.49.0-1.20.00.5-0.8-1.8-0.50.2-1.2-0.60.91.01.50.90.6-2.00.7-2.10.10.3-1.1-0.23.0-0.30.3
Locomotor activity1.42.24.8-2.21.61.8-1.40.31.5-0.8-1.5-1.41.41.52.01.51.3-1.81.4-2.01.10.9-1.2-1.20.5-1.71.7
Locomotor testing distance0.51.23.2-1.30.81.1-1.10.00.8-0.4-0.9-1.20.91.11.61.10.9-1.41.0-1.60.80.7-0.9-0.70.5-1.81.8
Locomotor testing rearing0.41.32.9-1.10.61.0-1.3-0.00.5-0.6-1.3-1.31.21.21.71.31.0-1.61.2-1.71.21.0-1.3-0.91.1-1.01.0
Locomotion in novel chamber0.10.10.30.20.30.3-0.20.50.4-0.50.1-0.30.00.3-0.40.30.40.20.3-0.00.20.2-0.1-0.0-0.0-0.50.5
Locomotion in novel chamber post-restriction0.51.42.1-0.81.21.3-1.41.11.2-1.3-1.4-1.31.21.31.21.41.4-1.11.4-1.01.41.4-1.3-1.40.00.3-0.3
Fecal boli incidents, locomotor time 10.30.92.41.5-1.2-1.30.8-0.5-1.20.70.90.9-1.0-1.0-0.9-1.0-0.91.0-1.01.2-0.9-0.70.80.60.10.8-0.8
Change in fecal boli incidents, locomotor task1.61.74.1-1.90.81.1-1.3-0.50.5-0.5-1.5-1.11.51.41.71.31.0-1.91.1-2.01.10.8-1.5-0.51.9-1.11.1
Time >=10cm from walls, locomotor time 12.22.86.0-1.00.61.2-2.1-0.20.5-0.9-1.9-2.01.71.82.41.91.6-2.21.9-2.41.41.7-2.0-1.11.7-1.61.6
Bouts of movement, locomotor time 10.20.30.60.6-0.4-0.40.5-0.2-0.20.40.80.3-0.6-0.5-0.7-0.5-0.40.7-0.60.4-0.7-0.60.60.2-0.3-0.50.5
Total resting periods, locomotor time 10.20.30.50.5-0.5-0.40.5-0.3-0.30.50.70.4-0.7-0.5-0.6-0.5-0.40.6-0.60.3-0.7-0.70.60.4-0.0-0.30.3
Rest time, locomotor task time 10.20.30.60.5-0.5-0.40.6-0.7-0.50.70.50.7-0.7-0.4-0.5-0.4-0.50.3-0.40.1-0.8-0.60.70.5-0.00.1-0.1
Distance moved, locomotor task time 10.41.12.1-1.51.11.1-1.20.81.0-1.1-1.3-1.21.41.01.01.11.1-1.21.1-0.91.21.1-1.2-0.80.1-0.20.2
Vertical activity count, locomotor time 10.32.44.2-1.51.51.6-1.71.41.5-1.6-1.7-1.71.91.41.41.61.7-1.51.6-1.12.11.8-1.9-1.80.1-0.40.4
Time >=10cm from walls, locomotor time 20.82.46.0-1.71.11.4-1.6-0.20.7-0.9-2.2-1.41.71.82.41.71.6-2.41.7-2.11.41.5-1.7-0.91.20.5-0.5
Bouts of movement, locomotor time 20.10.20.6-0.80.70.7-0.10.20.7-0.2-0.3-0.10.50.50.50.30.2-0.40.3-0.60.10.1-0.1-0.60.2-0.40.4
Total resting periods, locomotor time 20.00.10.4-0.60.40.40.3-0.30.40.2-0.00.30.20.30.20.0-0.2-0.2-0.0-0.5-0.3-0.30.2-0.30.4-0.40.4
Rest time, locomotor task time 20.40.72.51.0-1.3-0.90.4-1.6-1.41.10.70.3-0.7-0.4-0.5-0.4-0.70.2-0.5-0.4-0.9-0.70.40.51.3-1.11.1
Distance moved, locomotor task time 20.91.21.9-1.11.21.0-1.11.31.0-1.3-1.3-1.01.20.90.81.01.3-0.91.1-0.21.31.4-1.1-0.7-0.61.4-1.4
Vertical activity count, locomotor time 20.51.32.1-1.11.21.0-1.11.00.9-1.0-1.5-1.01.30.91.01.11.4-1.21.2-0.51.41.3-1.3-1.0-0.01.2-1.2
Light reinforcement 10.41.63.8-0.80.50.9-1.80.80.7-1.2-1.0-1.91.41.11.51.31.2-1.01.3-1.31.71.5-1.6-0.50.2-1.61.6
Light reinforcement 20.20.51.3-0.3-0.00.3-1.1-0.1-0.1-0.5-0.9-1.20.90.60.80.70.7-0.90.8-1.01.01.0-1.10.10.4-0.50.5
Bone: marrow area1.63.911.4-2.71.11.7-1.9-1.50.4-0.6-2.5-1.72.12.22.52.01.7-3.21.9-3.41.11.4-2.1-1.03.30.7-0.7
Bone: maximum diameter0.30.74.3-0.1-0.9-0.60.5-2.1-1.21.10.20.6-0.5-0.1-0.3-0.3-0.6-0.4-0.3-0.8-1.1-0.80.30.81.60.5-0.5
Bone: maximum force0.91.72.7-1.01.21.3-1.60.91.0-1.4-1.4-1.61.41.41.21.51.5-1.21.5-1.21.61.6-1.5-1.50.80.1-0.1
Bone: maximum moment0.61.01.7-0.80.91.0-1.20.60.7-1.1-1.2-1.21.11.11.01.21.2-1.01.2-0.91.21.3-1.2-1.20.70.5-0.5
Mean time between licks in bursts0.31.96.40.6-1.6-1.31.4-2.5-1.82.01.11.3-1.3-1.0-0.5-1.1-1.50.3-1.3-0.2-1.8-1.71.11.71.5-0.80.8
Mean num. licks in bursts0.30.85.0-0.11.30.7-0.22.21.5-1.2-0.2-0.00.30.20.00.30.60.50.41.00.90.7-0.2-0.9-1.71.1-1.1
Cd content in liver0.40.42.11.1-0.9-0.90.10.0-0.90.30.30.1-0.1-0.6-0.5-0.4-0.40.4-0.21.00.30.3-0.2-0.0-0.21.4-1.4
Co content in liver1.31.63.2-1.01.11.1-1.61.31.0-1.4-1.4-1.51.51.21.31.31.4-1.01.4-0.71.81.7-1.7-1.4-0.30.2-0.2
Cu content in liver0.50.63.50.60.2-0.20.61.30.5-0.20.80.4-0.5-0.7-0.9-0.6-0.31.2-0.61.4-0.2-0.40.7-0.0-1.9-0.20.2
Fe content in liver0.40.41.3-0.00.70.6-0.81.10.7-0.9-0.4-0.80.50.60.30.60.8-0.00.70.00.90.9-0.6-0.8-0.90.2-0.2
K content in liver1.21.22.11.4-1.2-1.21.0-0.7-1.11.01.41.0-1.3-1.2-0.9-1.0-1.11.5-1.11.0-1.2-1.01.21.0-0.9-0.80.8
Mg content in liver1.81.94.01.4-1.9-1.51.3-2.0-1.81.71.41.1-1.5-1.4-0.7-1.2-1.50.9-1.40.2-1.6-1.61.11.30.6-1.51.5
Mn content in liver1.11.26.10.9-1.7-1.30.6-2.5-2.01.50.70.6-1.0-0.7-0.2-0.6-0.80.0-0.8-0.5-1.2-0.90.41.21.7-0.20.2
Na content in liver0.30.32.0-0.20.50.4-0.10.80.8-0.40.2-0.2-0.10.10.10.10.20.50.10.20.10.00.3-0.2-1.4-1.11.1
Rb content in liver0.50.52.01.4-1.1-1.00.6-0.7-1.20.80.70.6-0.7-0.8-0.5-0.7-0.80.6-0.70.6-0.6-0.50.40.60.20.2-0.2
Se content in liver0.81.04.4-0.1-0.9-0.71.1-2.1-1.11.60.51.1-0.8-0.70.0-0.9-1.1-0.3-1.1-0.5-1.3-1.50.91.20.8-0.40.4
Sr content in liver0.20.21.70.2-0.3-0.3-0.1-0.7-0.60.4-0.10.0-0.10.10.10.1-0.1-0.40.2-0.1-0.00.2-0.00.2-0.21.3-1.3
Zn content in liver0.20.20.90.1-0.7-0.60.2-0.9-0.80.60.10.2-0.2-0.40.2-0.3-0.4-0.3-0.4-0.1-0.3-0.3-0.10.30.90.3-0.3
Bone: minimum diameter0.40.74.3-0.6-0.30.1-0.3-1.7-0.70.4-0.8-0.40.40.70.50.60.3-1.30.6-1.7-0.10.2-0.7-0.22.10.3-0.3
Time in familiar zone, hab. session 11.61.75.71.3-0.3-0.91.31.10.00.31.61.3-1.4-1.3-1.9-1.3-1.02.2-1.22.4-1.0-0.91.50.4-2.10.8-0.8
Time in novel zone, hab. session 11.71.95.2-1.70.71.2-1.5-0.70.4-0.5-1.7-1.31.61.51.91.41.2-2.21.3-2.31.21.0-1.6-0.61.7-0.60.6
Total zone transitions, hab. session 10.50.81.70.9-0.9-0.90.7-0.5-0.70.81.00.5-0.9-0.9-0.9-0.8-0.90.9-0.80.6-0.8-0.80.90.7-0.8-1.31.3
Total locomotion distance, hab. session 10.81.12.21.5-1.2-1.11.0-0.6-1.00.91.30.8-1.2-1.1-1.1-1.0-1.01.3-1.00.8-1.0-1.01.01.0-0.8-1.21.2
Locomotion velocity, hab. session 10.50.71.21.0-0.9-0.80.8-0.4-0.60.71.00.6-0.9-0.8-0.8-0.7-0.80.9-0.80.6-0.8-0.80.80.8-0.8-1.11.1
Time in familiar zone, hab. session 20.70.84.4-0.40.80.8-0.71.41.2-0.9-0.1-0.90.40.50.50.60.60.20.6-0.10.60.6-0.4-0.8-1.0-2.12.1
Time in novel zone, hab. session 20.50.55.3-0.50.20.00.0-0.5-0.20.1-0.50.40.30.10.3-0.00.1-0.60.0-0.10.1-0.0-0.10.40.72.3-2.3
Total zone transitions, hab. session 20.40.54.01.0-0.6-0.4-0.10.1-0.30.10.5-0.4-0.4-0.2-0.3-0.0-0.10.60.00.0-0.00.10.10.1-0.6-2.02.0
Total locomotion distance, hab. session 21.21.65.12.2-1.6-1.40.8-0.4-1.20.91.60.4-1.4-1.2-1.2-1.0-1.01.6-0.90.9-0.9-0.71.01.0-0.5-2.12.1
Locomotion velocity, hab. session 21.72.36.22.5-2.0-1.71.2-0.8-1.51.21.80.8-1.7-1.5-1.4-1.3-1.31.8-1.31.1-1.2-1.11.41.3-0.5-2.12.1
Novel to familiar place preference ratio0.20.21.00.1-0.2-0.30.4-0.3-0.30.40.30.8-0.3-0.4-0.1-0.5-0.40.1-0.50.5-0.4-0.50.51.0-0.10.9-0.9
Novelty place preference0.10.20.8-0.20.1-0.10.3-0.3-0.10.30.10.7-0.2-0.20.2-0.3-0.3-0.2-0.40.2-0.4-0.40.40.90.10.9-0.9
Time in novel zone, NPP test0.10.20.9-0.50.30.10.2-0.20.10.2-0.10.6-0.0-0.10.2-0.2-0.1-0.4-0.20.1-0.3-0.30.30.80.21.0-1.0
Total zone transitions, NPP test2.02.95.32.3-2.1-2.11.7-1.1-1.91.82.01.5-1.9-2.0-2.0-1.8-1.81.9-1.81.6-1.6-1.51.71.6-0.7-0.60.6
Total locomotion distance, NPP test2.23.18.62.9-2.3-2.31.7-1.0-2.11.62.01.4-1.9-2.0-2.1-1.8-1.72.0-1.71.9-1.4-1.31.61.4-0.50.1-0.1
Locomotion velocity, NPP test3.04.311.93.5-2.8-2.72.0-1.2-2.51.92.41.6-2.3-2.4-2.3-2.1-2.12.4-2.12.2-1.7-1.62.01.7-0.7-0.30.3
Intraocular pressure0.20.31.20.7-0.2-0.40.40.7-0.0-0.10.60.4-0.2-0.5-0.4-0.5-0.40.8-0.31.0-0.2-0.10.20.1-1.10.8-0.8
Delta distance traveled before/after self-admin1.81.96.5-2.62.01.9-1.20.91.9-1.3-1.6-1.01.71.61.51.31.4-1.51.2-1.30.90.8-1.1-1.00.80.4-0.4
Delta ambulatory time before/after self-admin1.11.96.1-2.51.91.9-1.20.71.7-1.2-1.6-1.01.71.61.61.41.4-1.61.2-1.50.90.8-1.2-1.11.0-0.10.1
Parametrial fat weight1.12.65.8-0.31.11.3-2.22.11.3-2.1-1.3-2.41.71.51.31.81.9-0.62.0-0.82.22.4-1.8-1.5-0.5-0.60.6
Pavlov. Cond. lever latency5.97.511.4-2.32.92.9-3.23.33.1-3.4-2.6-3.23.02.82.62.93.0-2.03.0-1.63.43.3-3.0-3.1-0.6-0.70.7
Pavlov. Cond. magazine entry latency1.72.24.60.6-1.1-1.21.9-1.8-1.21.81.32.0-1.6-1.4-1.5-1.6-1.61.0-1.70.7-2.1-2.11.91.8-0.10.1-0.1
Pavlov. Cond. change in total contacts0.60.71.80.1-0.5-0.61.1-1.3-0.71.10.51.2-0.8-0.7-0.6-0.9-0.80.2-1.00.1-1.2-1.40.91.00.40.1-0.1
Pavlov. Cond. index score4.05.08.51.8-2.2-2.22.7-2.8-2.42.82.12.7-2.6-2.2-2.4-2.4-2.41.6-2.41.2-2.9-2.82.62.50.40.5-0.5
Pavlov. Cond. latency score4.25.39.01.8-2.3-2.32.7-2.9-2.52.92.12.8-2.6-2.2-2.5-2.4-2.51.6-2.51.1-3.0-2.92.62.60.50.4-0.4
Pavlov. Cond. lever contacts4.95.910.12.4-2.8-2.72.7-3.2-3.13.02.22.7-2.7-2.4-2.3-2.5-2.61.6-2.61.3-2.8-2.82.42.60.90.6-0.6
Pavlov. Cond. magazine entry number1.31.73.6-0.61.01.1-1.61.61.1-1.6-1.2-1.71.41.21.31.41.4-0.91.5-0.71.91.9-1.6-1.60.0-0.10.1
Pavlov. Cond. intertrial magazine entries0.20.31.70.40.1-0.0-0.41.30.3-0.7-0.1-0.40.4-0.10.3-0.00.20.20.10.90.80.6-0.5-0.6-0.80.1-0.1
Pavlov. Cond. lever-magazine prob. diff.4.25.28.41.8-2.2-2.22.7-2.8-2.42.72.12.8-2.6-2.2-2.4-2.4-2.41.7-2.51.3-2.9-2.82.62.60.30.6-0.6
Pavlov. Cond. response bias2.63.35.91.3-1.8-1.82.1-2.3-1.92.21.62.2-2.0-1.8-1.6-2.0-1.91.2-2.10.9-2.4-2.42.02.20.30.3-0.3
Pavlov. Cond. lever latency0.30.41.6-0.3-0.30.1-0.7-0.7-0.40.1-0.6-0.60.60.60.80.60.3-1.00.5-1.10.40.5-0.70.01.3-0.70.7
Pavlov. Cond. magazine entry latency0.40.61.60.5-0.7-0.80.9-0.9-0.90.80.60.9-0.8-0.7-0.6-0.8-0.80.4-0.70.5-0.9-0.80.80.60.41.3-1.3
Pavlov. Cond. change in total contacts0.10.20.4-0.30.60.30.50.40.6-0.10.20.6-0.3-0.1-0.5-0.3-0.10.3-0.20.5-0.3-0.40.4-0.2-0.60.5-0.5
Pavlov. Cond. index score0.20.41.00.2-0.0-0.30.9-0.1-0.10.30.50.8-0.6-0.5-0.8-0.6-0.50.7-0.60.7-0.7-0.70.70.1-0.41.0-1.0
Pavlov. Cond. latency score0.10.20.90.00.1-0.10.60.10.10.10.30.6-0.4-0.3-0.7-0.4-0.30.5-0.40.6-0.5-0.50.5-0.1-0.40.9-0.9
Pavlov. Cond. lever contacts0.20.31.70.20.3-0.00.60.70.4-0.20.50.4-0.5-0.4-0.7-0.4-0.20.9-0.40.9-0.3-0.40.6-0.1-1.30.6-0.6
Pavlov. Cond. magazine entry number0.20.20.7-0.40.40.4-0.50.40.5-0.3-0.3-0.40.40.40.50.40.3-0.40.4-0.40.40.3-0.4-0.0-0.3-0.90.9
Pavlov. Cond. intertrial magazine entries0.20.53.1-0.1-0.5-0.30.4-0.9-0.40.80.40.4-0.2-0.40.1-0.4-0.6-0.0-0.6-0.4-0.7-0.90.40.90.4-1.81.8
Pavlov. Cond. lever-magazine prob. diff.0.20.31.00.3-0.0-0.30.8-0.1-0.10.30.50.8-0.6-0.5-0.8-0.6-0.40.6-0.50.7-0.6-0.60.70.1-0.31.0-1.0
Pavlov. Cond. response bias0.50.71.20.6-0.3-0.61.1-0.1-0.30.50.90.9-1.0-0.8-1.0-0.9-0.71.1-0.81.1-0.9-0.91.00.3-0.80.8-0.8
Time in closed arm before self-admin0.10.10.4-0.70.20.2-0.2-0.40.00.0-0.3-0.20.30.20.00.20.1-0.30.1-0.4-0.0-0.0-0.20.20.6-0.70.7
Time in closed arm after self-admin0.10.10.30.5-0.2-0.20.2-0.3-0.40.2-0.00.20.00.0-0.30.0-0.10.0-0.0-0.0-0.10.2-0.1-0.20.00.6-0.6
Time in open arm before self-admin0.60.71.50.1-0.4-0.61.2-0.6-0.40.90.71.2-0.8-0.7-0.6-1.0-0.90.5-1.00.7-1.0-1.21.10.8-0.21.2-1.2
Time in open arm after self-admin0.20.20.8-0.40.1-0.10.4-0.10.10.20.40.5-0.4-0.3-0.3-0.5-0.30.1-0.50.4-0.6-0.70.60.70.50.9-0.9
Bone: periosteal estimation1.02.46.8-2.11.11.5-1.5-0.70.7-0.8-1.9-1.41.61.91.71.81.5-2.31.7-2.60.91.2-1.6-1.02.20.4-0.4
Bone: periosteal perimeter0.20.52.3-0.90.20.5-0.4-1.1-0.10.1-0.8-0.50.40.90.60.70.5-1.10.6-1.50.10.2-0.6-0.41.20.3-0.3
Bone: post-yield work0.30.53.20.1-0.9-0.6-0.0-1.7-1.20.9-0.1-0.0-0.1-0.00.2-0.1-0.3-0.6-0.1-0.8-0.3-0.1-0.10.41.80.1-0.1
Progressive ratio test 1 active lever presses0.30.52.50.3-0.5-0.70.7-0.5-0.70.60.30.9-0.6-0.7-0.4-0.7-0.50.3-0.60.8-0.4-0.40.60.20.21.6-1.6
Progressive ratio test 1 breakpoint0.30.42.40.3-0.4-0.60.7-0.5-0.70.60.20.9-0.5-0.6-0.3-0.6-0.50.2-0.50.7-0.4-0.40.60.20.31.6-1.6
Progressive ratio test 1 inactive lever presses0.00.10.30.6-0.3-0.3-0.20.5-0.2-0.10.2-0.2-0.0-0.3-0.1-0.10.10.50.00.60.50.50.0-0.2-0.5-0.20.2
Progressive ratio test 2 active lever presses0.50.61.40.9-0.7-0.90.9-0.1-0.60.50.90.9-0.9-1.0-0.9-0.9-0.71.0-0.91.2-0.8-0.70.90.8-0.50.4-0.4
Progressive ratio test 2 breakpoint0.50.71.60.9-0.6-0.80.9-0.0-0.50.50.90.9-1.0-1.0-0.9-1.0-0.81.1-0.91.3-0.8-0.70.90.8-0.60.5-0.5
Progressive ratio test 2 inactive lever presses0.41.12.10.5-1.2-1.30.9-1.4-1.51.30.81.2-0.9-1.1-0.6-1.1-1.10.5-1.10.8-1.0-1.01.01.20.81.2-1.2
Incentive Sensitization - Responses0.20.50.90.6-0.6-0.70.7-0.2-0.40.50.90.5-0.8-0.8-0.7-0.8-0.70.8-0.80.7-0.9-0.80.81.0-0.5-0.70.7
Incentive Sensitization - Breakpoint0.20.61.00.7-0.6-0.70.7-0.1-0.40.51.00.5-0.8-0.9-0.8-0.8-0.71.0-0.80.8-0.8-0.80.80.9-0.7-0.70.7
Sum of active levers in priming session hrs 5-60.20.20.6-0.0-0.3-0.40.7-0.8-0.50.70.30.8-0.4-0.4-0.3-0.5-0.60.0-0.60.2-0.7-0.70.60.00.1-0.10.1
Progressive ratio2.88.211.2-3.03.23.3-3.02.73.3-3.2-3.0-3.13.13.12.73.33.2-2.53.3-2.53.13.2-2.8-3.1-0.3-0.90.9
Food seeking constrained by brief footshock0.10.10.7-0.20.50.20.20.60.4-0.3-0.20.10.1-0.0-0.3-0.10.20.2-0.10.5-0.0-0.00.10.1-0.80.6-0.6
Seeking ratio, punishment vs. effort2.04.56.71.8-2.2-2.42.4-2.1-2.32.42.12.5-2.3-2.3-2.0-2.5-2.31.7-2.61.9-2.5-2.62.12.50.00.5-0.5
Retroperitoneal fat weight0.00.10.60.7-0.2-0.2-0.50.5-0.2-0.4-0.1-0.80.20.00.10.20.40.20.40.20.60.6-0.2-0.3-0.30.1-0.1
Reaction time number correct0.41.53.2-1.31.41.3-1.61.81.6-1.5-0.9-1.41.31.11.11.21.3-0.61.2-0.41.51.3-1.2-1.0-0.6-0.10.1
Reaction time mean minus median0.42.64.31.8-1.9-1.82.0-2.1-2.02.01.32.0-1.8-1.6-1.4-1.7-1.91.2-1.60.9-2.0-1.81.61.4-0.00.5-0.5
Reaction time mean minus median AUC0.74.57.02.3-2.4-2.42.6-2.4-2.62.61.82.6-2.3-2.2-1.7-2.2-2.31.5-2.21.6-2.3-2.22.11.80.01.6-1.6
Reaction time num false alarms0.10.21.1-0.30.00.20.1-0.60.00.2-0.2-0.10.20.30.60.2-0.0-0.50.1-0.8-0.1-0.1-0.3-0.00.7-1.11.1
Reaction time num false alarms AUC0.20.52.4-0.90.50.7-0.2-0.40.5-0.1-0.5-0.40.50.71.00.60.3-0.90.4-1.20.10.1-0.6-0.30.7-1.51.5
Reaction time trials correct on left0.41.53.2-1.31.41.3-1.61.81.6-1.5-0.9-1.41.31.11.11.21.3-0.61.2-0.41.51.3-1.2-1.0-0.6-0.10.1
Reaction time trials on left0.41.42.9-1.31.41.3-1.61.71.5-1.5-0.9-1.31.31.11.11.11.3-0.71.1-0.41.51.3-1.1-1.0-0.5-0.10.1
Reaction time mean1.53.27.12.2-2.4-2.21.9-2.6-2.72.31.31.8-1.8-1.6-1.5-1.6-1.81.0-1.60.8-1.9-1.61.51.51.01.6-1.6
Reaction time mean AUC1.33.26.82.2-2.3-2.21.9-2.5-2.62.21.31.8-1.8-1.6-1.5-1.6-1.81.1-1.60.9-1.8-1.61.51.40.81.7-1.7
Median of all reaction times1.42.25.31.9-2.0-1.81.4-2.2-2.31.81.01.3-1.4-1.2-1.3-1.2-1.40.7-1.20.6-1.4-1.11.11.11.21.7-1.7
Reaction time omissions1.01.63.41.8-1.8-1.61.4-1.8-1.81.71.01.1-1.4-1.2-1.1-1.2-1.20.9-1.20.4-1.2-1.21.11.00.6-0.00.0
Reaction time false alarm rate0.30.52.2-0.1-0.4-0.20.8-1.5-0.50.90.10.6-0.3-0.10.3-0.2-0.5-0.4-0.4-0.8-0.9-0.80.20.31.2-1.11.1
Reaction time premature initiation rate0.10.10.3-0.20.20.2-0.50.10.1-0.3-0.3-0.30.50.4-0.00.40.4-0.20.4-0.30.40.4-0.30.30.40.2-0.2
Reaction time premature initiations0.41.22.5-1.11.21.2-1.61.21.2-1.4-1.0-1.21.31.20.81.21.3-0.81.2-0.71.41.3-1.1-0.40.0-0.00.0
Std. dev. reaction times0.72.56.21.3-1.8-1.72.0-2.5-2.02.21.12.0-1.7-1.4-1.2-1.5-1.70.8-1.50.5-2.0-1.81.51.30.70.9-0.9
Reaction time trials completed0.41.42.9-1.31.41.3-1.61.71.5-1.5-0.9-1.31.31.11.11.11.3-0.71.1-0.41.51.3-1.1-1.0-0.5-0.10.1
Reaction time trials AUC0.41.32.8-1.21.31.2-1.61.71.4-1.5-0.9-1.41.31.11.11.11.3-0.61.1-0.41.51.3-1.1-1.0-0.5-0.20.2
Run reversals in cocaine runway, females0.10.10.60.50.1-0.10.20.60.1-0.40.00.1-0.2-0.2-0.4-0.00.00.50.10.70.10.4-0.2-0.2-0.20.8-0.8
Run reversals in cocaine runway, males0.70.81.40.8-1.0-0.90.9-1.1-1.01.11.01.0-1.1-0.8-0.9-0.8-1.00.6-0.90.4-1.2-1.00.91.10.5-0.40.4
Latency to leave start box in cocaine runway0.70.92.51.1-1.5-1.20.7-1.6-1.61.40.70.7-0.9-0.8-0.9-0.8-0.90.5-0.90.3-1.0-0.90.71.20.70.4-0.4
Latency to leave start box in cocaine runway, F0.70.92.21.2-1.4-1.30.8-1.3-1.51.50.70.8-0.9-1.1-0.6-0.9-1.00.5-1.00.5-0.9-0.90.70.80.20.6-0.6
Latency to leave start box in cocaine runway, M0.10.10.60.2-0.3-0.1-0.1-0.6-0.40.10.1-0.2-0.20.2-0.50.20.10.10.1-0.4-0.3-0.10.00.50.8-0.40.4
Std. dev. time between licks in bursts0.61.16.7-0.1-1.1-0.70.8-2.6-1.41.50.40.6-0.6-0.2-0.4-0.4-0.8-0.3-0.6-1.1-1.4-1.20.40.92.1-0.80.8
Total sessions with >9 infusions0.20.31.8-0.00.3-0.00.80.10.20.2-0.11.0-0.2-0.30.4-0.4-0.3-0.1-0.30.6-0.1-0.20.4-0.3-0.41.3-1.3
Short access day 1 total inactive lever presses0.40.82.00.5-0.9-1.00.9-1.4-1.31.30.31.1-0.6-0.8-0.0-0.9-0.8-0.0-0.90.4-0.7-0.90.70.31.01.0-1.0
Short access day 10 total inactive lever presses0.10.65.40.6-0.8-0.5-0.3-0.4-0.50.40.5-0.50.1-0.30.3-0.2-0.40.2-0.2-0.30.0-0.20.30.4-0.3-2.32.3
Short access day 1 total infusions0.50.92.90.3-0.6-0.81.3-0.8-0.81.00.41.7-0.7-0.90.0-1.0-1.00.3-1.00.9-0.7-0.91.00.80.41.7-1.7
Short access day 10 total infusions0.30.51.40.8-0.4-0.71.00.0-0.50.60.51.2-0.6-1.0-0.1-0.9-0.80.6-0.81.2-0.2-0.50.9-0.1-0.80.7-0.7
Short access total infusions0.60.82.80.7-0.5-0.81.3-0.4-0.70.80.41.5-0.8-0.9-0.1-1.0-0.90.4-0.91.2-0.5-0.70.90.1-0.21.7-1.7
Short access day 1 locomotion0.50.91.51.2-1.1-1.11.2-0.8-1.01.10.91.1-1.1-1.0-0.2-1.0-1.10.7-1.00.7-0.9-1.01.10.60.1-0.30.3
Short access day 10 total locomotion0.73.06.6-2.31.41.8-1.7-0.11.2-1.1-2.0-1.61.82.12.41.91.7-2.41.8-2.61.21.3-1.9-1.41.8-1.11.1
Short access total locomotion0.20.31.3-0.40.10.2-0.1-0.6-0.10.1-0.7-0.00.30.51.10.40.3-1.00.4-0.80.30.2-0.6-0.51.10.4-0.4
One hour access (0.3 mA shock)1.51.72.61.3-1.3-1.41.2-0.5-1.01.11.61.1-1.4-1.5-1.3-1.4-1.41.6-1.41.3-1.5-1.41.51.3-0.7-1.41.4
Compulsive drug intake1.21.810.11.1-1.8-1.10.2-1.7-1.61.31.1-0.0-0.7-0.5-0.7-0.5-0.90.7-0.5-0.6-1.1-0.70.51.50.9-3.23.2
One hour access (shock baseline)0.20.62.40.40.2-0.30.80.80.2-0.10.51.0-0.6-0.8-0.6-0.7-0.40.8-0.71.5-0.4-0.50.7-0.1-1.01.5-1.5
Social response proportion0.70.92.6-1.20.50.8-0.8-0.50.2-0.2-1.1-0.60.91.01.01.00.7-1.40.9-1.40.80.7-1.0-0.61.61.0-1.0
Social responses0.81.02.4-1.41.01.2-1.00.10.8-0.5-1.2-0.91.01.11.31.21.0-1.41.1-1.60.90.8-1.0-0.90.40.1-0.1
Social time0.81.26.40.7-1.3-0.70.4-1.8-1.21.30.50.0-0.6-0.30.3-0.2-0.8-0.2-0.4-1.1-0.8-0.80.10.71.6-2.52.5
Soleus weight0.61.812.4-0.9-0.9-0.1-0.4-3.1-1.61.1-0.9-0.20.60.61.50.50.0-2.10.3-2.5-0.5-0.2-0.90.53.5-0.10.1
Bone: stiffness0.61.12.4-0.70.81.0-1.51.10.9-1.2-0.9-1.61.11.01.01.11.2-0.71.2-0.81.31.3-1.2-1.10.3-0.70.7
Tibialis anterior weight0.10.52.0-0.10.80.7-0.61.41.0-1.0-0.2-0.80.40.50.50.70.70.10.70.10.60.7-0.5-0.6-0.5-0.80.8
Time to tail flick, vehicle, before self-admin0.60.76.60.9-0.3-0.0-0.30.50.2-0.20.4-0.8-0.10.0-0.40.30.10.50.3-0.30.40.4-0.4-0.5-0.5-2.62.6
Time to tail flick, vehicle, after self-admin0.20.41.20.3-0.6-0.60.7-0.8-0.60.80.40.7-0.4-0.5-0.3-0.6-0.60.3-0.60.2-0.6-0.70.50.20.11.1-1.1
Time to tail flick, test, before self-admin0.40.42.7-0.40.60.5-0.40.90.9-0.50.2-0.40.10.2-0.10.20.10.40.20.00.20.10.1-0.5-1.0-1.61.6
Time to tail flick, test, after self-admin2.12.24.01.1-1.1-1.41.5-0.4-0.91.31.91.4-1.6-1.7-1.9-1.7-1.71.9-1.61.7-1.7-1.72.01.4-1.40.1-0.1
Delta time to tail flick, vehicle, before/after SA1.82.06.80.8-0.8-1.21.6-0.7-1.01.01.01.8-1.1-1.4-1.1-1.5-1.21.1-1.51.7-1.2-1.41.60.9-0.62.6-2.6
Delta time to tail flick, test, before/after SA0.91.12.11.5-1.2-1.31.0-0.4-1.20.91.10.8-1.1-1.3-1.3-1.1-1.01.3-1.01.2-0.8-0.81.01.0-0.50.8-0.8
Tibia length1.33.510.1-2.21.11.7-2.1-0.80.7-1.0-2.1-1.92.12.02.52.01.8-2.71.8-3.21.31.4-2.1-0.92.6-0.90.9
Ambulatory time before self-admin0.00.10.40.6-0.5-0.40.2-0.2-0.40.30.30.1-0.5-0.3-0.1-0.1-0.30.1-0.1-0.0-0.10.00.20.5-0.3-0.30.3
Ambulatory time after self-admin0.91.42.6-1.61.21.4-1.20.41.2-0.9-1.3-1.21.31.41.51.41.2-1.51.3-1.60.91.0-1.3-0.70.9-0.80.8
Bone: tissue strength0.10.11.20.1-0.0-0.1-0.1-0.0-0.2-0.1-0.4-0.10.30.10.10.10.2-0.40.10.00.40.4-0.3-0.30.51.1-1.1
Total heroin consumption0.10.11.3-0.3-0.00.1-0.1-0.10.10.0-0.1-0.20.10.10.40.10.0-0.10.0-0.50.1-0.2-0.00.1-0.2-1.21.2
Bone: trabecular number1.93.67.32.6-1.9-2.11.90.1-1.31.22.41.8-2.0-2.3-2.6-2.1-2.02.7-2.02.6-1.4-1.51.91.6-1.2-0.90.9
Bone: trabecular spacing2.73.97.9-2.62.02.2-2.00.11.5-1.4-2.6-1.72.12.42.52.12.1-2.82.1-2.61.71.8-1.9-1.61.31.2-1.2
Bone: trabecular thickness1.41.94.92.2-1.4-1.51.20.2-1.00.71.81.0-1.4-1.5-2.1-1.3-1.32.2-1.32.0-1.0-0.91.31.1-1.0-0.50.5
Bone: trabecular tissue density0.10.21.3-1.10.70.5-0.1-0.10.60.0-0.30.30.30.30.60.10.1-0.50.1-0.2-0.3-0.20.10.0-0.10.8-0.8
Water consumed over 24 hours0.00.10.4-0.1-0.2-0.0-0.1-0.6-0.30.2-0.1-0.1-0.00.10.20.10.0-0.30.0-0.5-0.2-0.10.00.20.6-0.20.2
Number of responses in last shaping day0.60.74.2-1.10.30.50.1-1.4-0.20.5-0.80.50.30.70.50.50.2-1.30.3-1.2-0.5-0.1-0.60.32.11.4-1.4