Hub : Genes

Tap2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Tap2 0.17 0.07 3.3e-13 0.12 0.14 0.14 0.14 1.2e-09 3.9e-11 1.5e-11 3.9e-11
2 Eye mRNA stability Tap2 0.74 0.14 8.2e-06 0.08 0.13 0.06 0.08 2.5e-02 5.1e-03 5.2e-02 2.6e-02
3 IC gene expression Tap2 0.38 0.12 8.3e-16 0.2 0.28 0.25 0.25 6.8e-09 3.8e-12 6.6e-11 6.1e-11
4 NAcc mRNA stability Tap2 0.28 0.08 0.0e+00 0.31 0.34 0.35 0.35 8.5e-48 3.1e-54 1.1e-55 5.6e-55
5 Brain gene expression Tap2 0.21 0.07 0.0e+00 0.17 0.2 0.18 0.18 1.7e-15 1.8e-18 8.0e-17 8.0e-17
6 PL gene expression Tap2 0.12 0.05 2.8e-16 0.15 0.16 0.14 0.14 1.2e-15 7.1e-17 3.6e-15 1.9e-15
7 NAcc gene expression Tap2 0.07 0.04 3.2e-11 0.07 0.06 0.06 0.06 1.0e-10 6.8e-09 5.8e-09 3.7e-09
8 LHb mRNA stability Tap2 0.54 0.14 1.4e-11 0.39 0.36 0.41 0.41 2.3e-10 1.4e-09 6.4e-11 7.9e-11
9 BLA mRNA stability Tap2 0.49 0.11 0.0e+00 0.4 0.49 0.5 0.49 7.7e-23 1.5e-29 1.3e-29 1.8e-29
10 pVTA mRNA stability Tap2 0.45 0.11 0.0e+00 0.42 0.41 0.42 0.43 4.2e-36 1.0e-35 7.3e-37 1.5e-37
11 Liver gene expression Tap2 0.27 0.09 0.0e+00 0.32 0.31 0.31 0.31 6.9e-36 6.0e-35 2.6e-35 4.5e-35
12 Brain mRNA stability Tap2 0.65 0.08 0.0e+00 0.63 0.65 0.66 0.66 1.5e-74 1.5e-79 1.3e-80 5.0e-81
13 Liver mRNA stability Tap2 0.38 0.09 0.0e+00 0.5 0.5 0.51 0.51 1.2e-62 2.6e-64 4.6e-65 1.2e-65
14 Adipose gene expression Tap2 0.61 0.1 0.0e+00 0.51 0.54 0.54 0.54 3.6e-65 1.4e-70 1.7e-70 5.2e-71
15 PL mRNA stability Tap2 0.48 0.1 0.0e+00 0.52 0.53 0.6 0.6 2.4e-66 2.2e-68 3.2e-81 7.4e-82
16 RMTg gene expression Tap2 0.18 0.1 1.9e-03 0.1 0.13 0.09 0.1 1.2e-03 2.5e-04 2.4e-03 1.4e-03
17 Adipose mRNA stability Tap2 0.63 0.09 0.0e+00 0.69 0.72 0.72 0.73 1.3e-106 5.4e-114 4.6e-116 7.1e-117
18 IL mRNA stability Tap2 0.43 0.14 4.3e-09 0.28 0.22 0.29 0.29 1.8e-07 5.8e-06 8.9e-08 1.1e-07
19 OFC mRNA stability Tap2 0.51 0.13 1.3e-11 0.26 0.35 0.4 0.41 8.2e-07 3.3e-09 1.2e-10 6.1e-11
20 IC mRNA stability Tap2 0.47 0.13 0.0e+00 0.26 0.37 0.37 0.35 1.5e-11 2.5e-16 1.4e-16 1.6e-15
21 BLA gene expression Tap2 0.53 0.14 0.0e+00 0.42 0.47 0.48 0.48 3.6e-24 1.7e-27 1.1e-28 3.5e-28
22 OFC gene expression Tap2 0.42 0.14 1.9e-06 0.03 0.04 0.11 0.07 5.5e-02 5.0e-02 1.4e-03 8.3e-03
23 Liver intron excision ratio chr20_4650951_4651037 0.07 0.04 5.3e-03 0.01 -0 -0 -0 1.4e-02 6.0e-01 5.1e-01 7.4e-01
24 Liver intron excision ratio chr20_4651537_4652216 0.07 0.04 6.0e-03 0.01 -0 0 -0 1.9e-02 5.2e-01 3.7e-01 7.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.72.96.2-2.4-1.7-1.8-1.80.0-1.2-1.1-2.1-1.6-1.92.5-1.8-1.82.5-1.72.3-1.3-1.8-1.3-1.7-1.50.70.8-0.8
Area under the delay curve0.30.30.80.70.90.80.30.20.60.60.80.10.4-0.30.70.7-0.60.7-0.50.30.70.50.30.6-0.2-0.50.5
BMI with tail1.13.88.20.91.61.72.52.21.62.41.82.92.1-1.42.22.3-1.02.3-1.22.52.12.72.32.00.30.6-0.6
BMI without tail2.16.59.02.63.03.02.82.42.93.02.82.82.7-2.52.93.0-2.22.9-2.22.72.72.82.72.30.40.1-0.1
Body weight3.013.118.73.43.43.84.21.92.93.64.34.34.0-3.94.34.3-3.94.2-3.93.84.24.14.23.4-1.3-0.10.1
Weight adjusted by age1.82.85.91.91.41.61.70.00.91.12.21.41.8-2.11.81.7-2.41.8-1.91.31.81.62.01.6-1.4-1.61.6
Bone surface0.10.31.2-0.3-0.5-0.3-0.2-0.6-0.4-0.4-0.3-0.3-0.30.5-0.2-0.40.2-0.2-0.2-0.5-0.1-0.2-0.1-0.6-1.01.1-1.1
Bone volume0.20.31.2-0.9-0.5-0.5-0.50.1-0.3-0.3-0.7-0.5-0.61.1-0.4-0.50.9-0.40.6-0.4-0.4-0.3-0.5-0.5-0.20.8-0.8
Breakpoint value in progressive ratio session0.20.31.1-0.2-0.5-0.4-0.4-0.5-0.4-0.6-0.5-0.5-0.40.2-0.5-0.60.3-0.50.1-0.5-0.5-0.6-0.5-0.4-0.01.1-1.1
Number of licking bursts0.30.62.5-0.1-0.9-0.6-0.4-1.6-1.0-1.0-0.4-0.3-0.50.2-0.4-0.60.0-0.6-0.5-0.9-0.5-0.8-0.6-1.0-0.81.1-1.1
Context. condit. distance diff. score6.17.312.5-3.2-3.5-3.3-2.9-3.3-3.5-3.3-2.8-2.6-3.02.7-2.7-2.92.3-2.81.6-3.0-2.6-2.8-2.5-2.7-0.90.4-0.4
Locomotion velocity, session 11.51.63.2-0.6-1.1-1.2-1.6-1.4-1.2-1.7-1.2-1.8-1.31.0-1.4-1.50.8-1.50.9-1.5-1.4-1.6-1.4-1.3-0.0-0.90.9
Locomotion distance, session 11.41.83.1-1.8-1.3-1.5-1.4-0.2-1.0-1.1-1.7-1.2-1.51.6-1.4-1.41.7-1.41.6-1.1-1.5-1.2-1.4-1.11.60.6-0.6
Locomotion velocity, session 20.50.50.9-0.6-0.7-0.6-0.8-0.8-0.6-0.8-0.8-0.7-0.90.7-0.7-0.80.6-0.70.2-0.8-0.7-0.8-0.9-1.00.10.7-0.7
Locomotion distance, session 21.11.53.4-1.8-1.6-1.6-1.1-0.8-1.5-1.2-1.4-0.9-1.41.2-1.3-1.21.4-1.31.3-1.0-1.3-1.0-1.2-1.20.5-0.10.1
Locomotion velocity, session 30.20.31.20.50.70.60.21.00.90.6-0.10.40.1-0.30.20.30.30.20.20.20.20.10.10.51.10.6-0.6
Locomotion distance, session 31.92.13.4-1.7-1.4-1.5-1.7-0.4-1.1-1.3-1.8-1.3-1.71.4-1.7-1.51.8-1.71.7-1.4-1.6-1.5-1.6-1.01.30.4-0.4
Stereotopy head waving bouts, day 31.31.64.31.90.91.21.3-0.40.60.61.51.11.4-2.11.31.1-1.91.2-1.90.71.30.91.30.6-1.50.1-0.1
Stereotopy head waving duration, day 31.21.44.52.11.31.41.2-0.10.90.71.40.91.3-1.91.21.1-1.71.1-1.60.71.20.81.10.6-1.1-0.60.6
Locomotion velocity, session 75.15.612.8-3.6-2.9-3.0-2.4-1.3-2.8-2.2-2.8-2.1-2.72.7-2.6-2.52.9-2.52.8-1.9-2.4-2.0-2.2-1.70.5-0.80.8
Locomotion distance, session 76.07.511.6-3.4-2.9-3.2-3.1-1.4-2.7-2.6-3.2-2.8-3.12.8-3.2-2.93.2-3.13.3-2.7-3.0-2.8-2.9-2.31.2-0.90.9
Stereotopy head waving bouts, day 70.30.42.11.41.31.00.20.41.10.50.5-0.10.3-0.50.40.4-0.40.3-0.50.20.20.1-0.1-0.00.8-0.10.1
Stereotopy head waving duration, day 70.70.83.51.91.41.30.80.61.30.91.00.60.9-1.20.90.9-0.90.8-0.90.70.70.60.60.50.20.1-0.1
Locomotion velocity, session 81.31.57.7-0.4-1.5-1.2-1.2-2.8-1.9-2.0-0.7-1.2-1.10.5-0.8-1.20.1-1.0-0.5-1.5-0.7-1.4-0.8-1.4-1.40.1-0.1
Locomotion distance, session 85.58.015.7-3.8-4.0-3.6-2.8-3.1-3.9-3.4-3.0-2.4-3.12.7-2.8-3.02.6-2.91.9-2.8-2.7-2.7-2.5-2.6-0.70.6-0.6
Degree of sensitization distance0.30.32.0-0.2-0.7-0.5-0.2-1.2-0.9-0.8-0.1-0.3-0.10.2-0.3-0.4-0.3-0.3-0.3-0.4-0.2-0.50.0-0.4-1.4-0.20.2
Degree of sensitization stereotypy0.30.31.60.40.50.2-0.60.20.5-0.1-0.5-0.7-0.60.6-0.4-0.30.6-0.50.4-0.5-0.7-0.6-1.0-0.61.30.2-0.2
Conditioned locomotion0.70.82.20.60.20.61.1-0.20.20.60.81.20.9-0.61.00.8-0.91.0-1.30.71.10.91.10.6-1.51.1-1.1
Cocaine response after cond. corrected0.30.31.6-1.3-1.2-0.90.1-0.6-1.2-0.5-0.40.4-0.30.3-0.2-0.30.3-0.20.1-0.0-0.10.10.1-0.2-0.70.8-0.8
Cocaine response after cond. not corrected0.50.61.70.4-0.10.30.9-0.7-0.20.10.71.00.7-0.80.70.5-1.00.7-1.30.50.80.60.90.3-1.20.9-0.9
Cocaine response before conditioning3.54.212.93.62.62.71.80.52.31.62.51.52.3-2.62.22.0-2.71.9-2.81.42.01.31.91.5-0.90.3-0.3
Saline control response3.95.210.52.63.22.92.23.03.22.92.31.92.5-2.02.32.6-1.62.3-1.12.52.12.32.12.00.7-0.90.9
Bone: connectivity density1.32.04.6-2.1-1.8-1.7-1.4-0.5-1.5-1.1-1.7-1.3-1.52.0-1.4-1.51.7-1.41.6-1.1-1.3-1.0-1.2-1.4-0.20.9-0.9
Bone: cortical apparent density1.41.94.30.81.51.51.52.11.71.91.21.61.3-1.21.41.6-0.71.5-0.61.71.41.81.41.40.30.5-0.5
Bone: cortical area0.10.20.50.50.50.60.40.10.40.50.50.40.3-0.10.60.5-0.30.7-0.70.30.60.50.40.4-0.2-0.10.1
Bone: cortical porosity0.50.51.51.00.90.5-0.8-0.10.7-0.2-0.0-1.2-0.5-0.1-0.3-0.20.0-0.30.2-0.7-0.6-0.7-0.9-0.31.2-1.21.2
Bone: cortical porosity0.50.62.21.10.60.3-0.9-0.60.3-0.60.0-1.3-0.5-0.1-0.4-0.4-0.3-0.4-0.0-0.9-0.6-0.9-0.9-0.50.5-1.51.5
Bone: cortical thickness0.61.03.90.21.31.10.82.01.61.50.40.90.50.00.91.00.31.00.11.00.71.10.51.11.40.4-0.4
Bone: cortical thickness1.92.26.11.01.71.61.62.52.12.11.01.81.3-0.81.51.7-0.31.5-0.41.81.41.71.31.70.70.9-0.9
Bone: cortical tissue density1.31.83.80.81.51.41.52.01.71.81.21.51.3-1.21.41.6-0.81.5-0.61.71.41.71.41.40.20.5-0.5
Condit. Reinf. active minus inactive responses0.50.61.4-0.0-0.2-0.5-1.0-0.3-0.2-0.7-0.5-1.2-0.50.6-1.0-0.80.4-1.00.8-0.8-0.9-1.1-0.8-0.6-0.2-1.01.0
Condit. Reinf. active-inactive response ratio0.40.41.21.11.10.90.40.91.10.70.70.30.8-0.60.40.6-0.60.5-0.20.60.50.30.50.8-0.0-0.50.5
Condit. Reinf. active responses0.50.71.4-0.7-0.6-0.8-1.1-0.1-0.5-0.7-0.7-1.1-0.60.8-1.2-0.90.8-1.21.2-0.7-1.0-1.1-0.8-0.4-0.1-0.70.7
Condit. Reinf. inactive responses1.51.84.3-2.1-1.4-1.6-1.50.1-1.1-0.9-1.6-1.2-1.41.6-1.7-1.31.9-1.62.0-1.0-1.5-1.2-1.3-0.60.90.1-0.1
Incentive salience index mean1.92.43.5-1.5-1.7-1.7-1.8-1.6-1.7-1.8-1.5-1.8-1.61.6-1.7-1.71.2-1.71.1-1.8-1.6-1.9-1.6-1.5-0.7-0.50.5
Condit. Reinf. lever presses3.85.410.3-3.0-3.2-2.9-2.3-2.8-3.2-2.7-2.3-2.1-2.52.2-2.3-2.41.9-2.31.3-2.5-2.1-2.3-2.1-2.4-1.00.4-0.4
Condit. Reinf. active minus inactive responses0.60.82.21.51.21.10.60.20.90.71.10.50.9-1.00.90.8-1.10.7-1.00.50.90.40.81.1-0.7-0.50.5
Condit. Reinf. active-inactive response ratio0.81.02.51.61.01.00.6-0.40.60.41.30.51.0-1.30.90.8-1.60.7-1.40.50.90.41.00.9-1.4-0.90.9
Condit. Reinf. active responses0.10.20.70.80.60.60.20.30.60.30.40.10.4-0.50.20.3-0.40.2-0.30.20.30.00.40.6-0.3-0.20.2
Condit. Reinf. inactive responses0.10.21.00.20.40.30.31.00.70.50.00.40.10.00.20.30.30.20.20.40.20.30.10.30.80.6-0.6
Condit. Reinf. lever presses0.60.81.7-0.4-0.3-0.6-1.3-0.2-0.3-0.7-0.9-1.2-1.00.9-1.1-0.91.0-1.11.1-1.1-1.1-1.2-1.1-0.40.7-0.80.8
Condit. Reinf. lever reinforcers received0.10.10.70.80.50.4-0.10.10.50.10.3-0.10.2-0.30.00.1-0.3-0.1-0.2-0.00.1-0.20.10.5-0.2-0.20.2
Conditioned reinforcement - actives0.00.10.3-0.4-0.1-0.2-0.30.3-0.10.0-0.1-0.3-0.20.2-0.3-0.10.3-0.20.6-0.1-0.30.0-0.20.10.2-0.50.5
Conditioned reinforcement - inactives0.10.10.70.30.1-0.10.10.2-0.0-0.00.2-0.20.1-0.3-0.2-0.0-0.2-0.10.40.1-0.20.1-0.20.10.2-0.80.8
Conditioned locomotion0.20.31.1-0.2-0.4-0.5-0.5-0.5-0.6-0.4-0.2-0.7-0.50.3-0.4-0.40.1-0.40.5-0.5-0.4-0.3-0.2-0.3-0.7-1.01.0
Patch foraging indifference point 0 sec2.24.16.82.22.62.42.12.32.52.42.21.82.2-2.32.02.2-1.92.0-1.22.52.02.11.92.00.1-0.50.5
Patch foraging indifference point AUC0.30.51.81.30.91.00.40.20.90.50.70.30.7-1.10.50.4-0.90.5-0.90.20.50.10.5-0.0-0.40.7-0.7
Delay disc. indifference point, 0s delay0.20.21.0-0.3-0.4-0.3-0.2-0.8-0.6-0.40.1-0.3-0.30.10.1-0.0-0.2-0.0-0.3-0.20.1-0.0-0.0-0.2-0.6-1.01.0
Delay disc. indifference point, 16s delay0.20.20.70.40.80.50.20.90.80.70.30.10.10.30.30.50.20.40.30.20.20.4-0.10.50.7-0.20.2
Delay disc. indifference point, 2s delay0.50.52.11.00.70.70.1-0.70.20.21.0-0.10.5-1.00.60.5-1.40.5-1.00.20.70.20.40.3-1.4-0.70.7
Delay disc. indifference point, 24s delay0.70.82.51.61.51.20.50.61.20.81.20.30.8-0.70.81.0-1.00.8-0.50.60.70.60.50.90.2-1.01.0
Delay disc. indifference point, 4s delay1.51.52.61.61.51.61.20.51.31.21.61.01.3-1.41.51.4-1.51.4-1.51.01.51.21.20.8-0.8-0.00.0
Delay disc. indifference point, 8s delay0.10.10.80.10.50.3-0.20.00.20.20.4-0.2-0.00.20.30.3-0.20.3-0.0-0.00.20.2-0.00.40.3-0.90.9
Indifference point function ln k0.20.40.9-0.1-0.6-0.5-0.5-1.0-0.7-0.8-0.6-0.6-0.60.7-0.5-0.60.3-0.60.0-0.8-0.5-0.8-0.7-0.6-0.60.1-0.1
Indifference point function log k0.20.40.9-0.1-0.6-0.5-0.5-1.0-0.7-0.8-0.6-0.6-0.60.7-0.5-0.60.3-0.60.0-0.8-0.5-0.8-0.7-0.6-0.60.1-0.1
Patch foraging total patch changes 0 sec2.24.17.02.22.72.42.12.42.62.52.11.92.1-2.32.02.2-1.92.0-1.22.52.02.11.91.90.3-0.60.6
Patch foraging total patch changes 12 sec2.12.74.92.12.22.01.71.92.22.01.71.41.9-1.91.61.6-1.61.5-1.11.71.61.61.71.2-0.20.2-0.2
Patch foraging total patch changes 18 sec1.42.27.00.71.71.51.72.62.02.11.11.71.3-1.51.31.6-0.61.5-0.22.01.31.81.21.21.40.4-0.4
Patch foraging total patch changes 24 sec0.30.53.1-0.40.60.2-0.11.80.91.0-0.20.0-0.00.1-0.20.10.60.01.10.6-0.10.4-0.20.11.6-0.40.4
Patch foraging total patch changes 6 sec1.82.75.21.72.32.01.62.22.22.21.71.31.8-1.61.51.7-1.41.6-0.72.01.51.81.51.30.6-1.01.0
Patch foraging time to switch 0 sec0.20.41.3-1.0-0.3-0.10.70.9-0.10.60.11.20.30.10.40.60.30.70.20.90.51.10.61.10.70.1-0.1
Patch foraging water rate 0 sec0.30.61.61.10.80.80.90.20.60.61.00.70.9-1.30.80.8-1.10.7-0.80.90.80.70.80.2-0.6-0.60.6
Patch foraging water rate 12 sec0.10.21.0-0.50.1-0.0-0.00.80.40.2-0.5-0.1-0.40.1-0.2-0.10.7-0.10.70.2-0.3-0.0-0.5-0.31.00.6-0.6
Patch foraging water rate 18 sec0.30.51.00.80.90.80.70.80.81.00.70.80.7-0.50.80.9-0.60.7-0.40.90.80.80.60.70.1-0.10.1
Patch foraging water rate 24 sec0.20.20.70.30.50.50.50.80.70.70.20.60.4-0.40.40.5-0.10.3-0.10.70.30.40.30.70.30.3-0.3
Patch foraging water rate 6 sec0.20.30.60.30.50.50.70.80.60.60.20.70.4-0.70.50.5-0.20.5-0.20.60.40.50.50.50.30.5-0.5
Seeking ratio, delayed vs. immediate footshock2.53.15.92.22.22.31.41.52.41.61.71.51.8-2.21.81.5-1.61.8-1.81.51.71.41.61.50.81.7-1.7
Distance traveled before self-admin0.20.20.6-0.4-0.4-0.00.4-0.3-0.30.00.20.7-0.0-0.40.50.2-0.40.5-0.80.40.50.60.50.2-0.20.8-0.8
Distance traveled after self-admin1.92.44.11.91.51.81.70.71.51.31.61.81.6-1.81.81.6-1.81.7-2.01.21.71.41.61.1-0.91.2-1.2
Extensor digitorum longus weight0.10.21.4-0.5-0.7-0.5-0.3-1.2-0.9-0.6-0.2-0.3-0.4-0.2-0.1-0.3-0.0-0.2-0.3-0.7-0.1-0.3-0.2-0.6-0.7-0.10.1
Bone: elastic displacement0.30.31.50.00.60.2-0.50.80.60.3-0.1-0.6-0.10.5-0.2-0.10.3-0.20.70.0-0.3-0.1-0.40.21.1-1.21.2
Bone: elastic work0.20.20.60.30.70.50.20.50.60.60.5-0.00.3-0.00.50.4-0.20.5-0.20.40.40.50.30.40.2-0.80.8
Bone: endosteal estimation1.63.510.92.60.91.51.7-1.60.20.42.31.51.9-2.41.81.5-3.11.7-3.30.92.01.21.90.9-3.3-0.60.6
Bone: endosteal perimeter0.51.06.90.7-0.7-0.10.3-2.4-1.1-0.90.60.30.3-0.70.4-0.0-1.40.4-1.9-0.40.5-0.10.6-0.1-2.6-0.10.1
Epididymis fat weight2.48.230.90.32.72.33.15.63.44.31.63.62.6-1.02.43.10.02.90.44.02.43.92.43.33.30.9-0.9
Delta time in closed arm before/after self-admin0.40.41.50.00.10.20.5-0.2-0.10.20.60.50.6-0.60.50.4-0.70.6-0.60.50.60.70.90.8-0.7-1.21.2
Delta time in open arm before/after self-admin0.10.10.3-0.00.30.1-0.00.50.40.3-0.2-0.1-0.10.1-0.10.10.3-0.10.4-0.1-0.2-0.1-0.2-0.20.1-0.30.3
Diff in mean of infusions in LGA sessions1.82.24.2-2.0-2.0-1.9-1.4-1.1-1.8-1.5-1.8-1.1-1.61.8-1.6-1.51.7-1.61.3-1.3-1.4-1.4-1.4-1.00.10.3-0.3
Delay discount exponential model param0.30.41.0-0.9-1.0-0.9-0.4-0.2-0.7-0.6-0.9-0.2-0.50.4-0.7-0.80.7-0.70.6-0.3-0.7-0.5-0.3-0.60.20.4-0.4
Extinction: sum of active levers before priming0.30.41.5-0.2-0.9-0.7-0.5-1.2-1.0-0.9-0.2-0.6-0.40.0-0.5-0.6-0.1-0.5-0.1-0.5-0.4-0.6-0.2-0.8-1.00.2-0.2
Active lever presses in extinction session 60.40.41.3-0.8-0.4-0.6-0.80.1-0.5-0.3-0.5-0.8-0.70.6-0.7-0.50.6-0.61.1-0.3-0.7-0.4-0.70.00.5-1.21.2
Bone: final force2.33.75.91.61.81.92.31.71.72.22.12.42.1-1.62.12.2-1.62.2-1.62.42.22.32.22.1-0.50.3-0.3
Bone: final moment1.62.64.21.31.61.61.91.41.51.91.82.01.8-1.41.81.9-1.31.8-1.32.01.82.01.81.8-0.3-0.20.2
Food consumed during 24 hour testing period0.50.72.00.3-0.00.41.1-0.4-0.20.40.91.30.9-0.91.00.8-1.21.0-1.30.81.00.91.00.5-1.40.3-0.3
Glucose1.82.914.1-0.3-2.0-1.6-1.4-3.7-2.6-2.5-0.5-1.5-1.1-0.3-1.3-1.5-0.7-1.5-0.5-1.9-1.1-1.9-0.8-1.5-2.1-1.71.7
Heart weight1.62.56.02.41.91.91.10.31.41.32.10.91.7-1.61.71.6-2.21.6-1.71.11.61.21.61.2-0.9-1.81.8
Delay discount hyperbolic model param0.40.41.2-0.9-1.1-1.0-0.3-0.2-0.8-0.6-0.9-0.1-0.50.5-0.8-0.80.8-0.80.7-0.3-0.7-0.5-0.3-0.60.30.4-0.4
Intermittent access intake day 1-15 change0.10.21.01.00.60.60.60.40.70.50.40.50.6-0.40.40.4-0.50.4-0.50.40.30.30.20.00.20.5-0.5
Intermittent access intake escalation0.30.72.01.31.31.10.71.31.41.10.60.70.8-0.50.60.8-0.40.6-0.30.80.50.60.40.51.00.4-0.4
Intermittent access intake escalation 20.10.10.60.80.30.20.1-0.10.20.00.00.00.10.20.00.1-0.2-0.0-0.2-0.2-0.0-0.2-0.1-0.50.30.3-0.3
Intermitt. access day 1 inactive lever presses0.20.72.80.4-0.9-0.40.5-1.5-1.0-0.70.10.50.4-0.80.1-0.2-0.80.0-1.1-0.10.2-0.10.1-0.6-1.31.7-1.7
Intermitt. access day 15 inactive lever presses0.20.51.10.90.50.60.70.10.30.50.80.60.8-1.10.70.5-1.00.7-0.80.70.60.80.70.5-0.2-0.60.6
Intermitt. access escalation Index1.31.93.6-1.9-1.8-1.5-1.2-1.2-1.6-1.6-1.6-0.9-1.21.3-1.3-1.51.3-1.30.6-1.1-1.2-1.3-1.2-1.30.11.9-1.9
Intermittent access day 1 total infusions2.03.25.5-1.8-1.6-2.0-2.2-1.0-1.7-1.6-1.6-2.3-1.91.7-2.0-1.81.6-2.02.3-1.7-2.0-1.7-1.8-1.20.1-2.02.0
Intermittent access day 15 total infusions0.30.41.4-0.30.0-0.4-0.70.40.0-0.1-0.5-0.9-0.50.6-0.8-0.50.6-0.71.2-0.4-0.8-0.5-0.7-0.20.6-0.90.9
Intermittent access terminal intake (last 3 days)0.20.31.50.20.3-0.1-0.60.30.1-0.1-0.1-0.9-0.40.1-0.6-0.30.2-0.50.9-0.3-0.6-0.4-0.6-0.30.4-1.21.2
Intermittent access total infusions0.60.72.0-0.6-0.3-0.7-1.10.0-0.4-0.5-0.6-1.3-0.80.7-1.0-0.80.7-0.91.4-0.7-1.1-0.8-0.9-0.40.4-1.41.4
Intermittent access day 1 locomotion0.40.51.9-1.0-0.5-0.7-0.70.1-0.5-0.4-0.6-0.8-0.80.5-0.7-0.50.7-0.61.1-0.3-0.7-0.3-0.50.00.2-1.41.4
Intermittent access day 15 total locomotion0.50.81.40.91.01.00.80.70.91.11.10.80.9-0.91.11.1-0.91.1-0.70.91.01.11.21.0-0.3-0.40.4
Intermittent access total locomotion0.20.21.30.10.60.30.10.70.50.70.30.10.1-0.00.20.5-0.00.30.30.40.20.50.30.50.2-1.11.1
Intermittent access standard deviation1.53.04.32.12.01.92.01.72.02.01.91.82.0-1.91.71.9-1.61.8-1.22.11.71.91.61.6-0.1-0.90.9
Left kidney weight2.511.417.03.03.73.93.82.73.53.93.73.93.6-3.34.04.1-3.13.9-3.23.53.93.73.63.5-0.00.1-0.1
Right kidney weight2.410.916.62.63.23.53.82.43.03.63.74.13.4-3.43.93.9-3.13.9-3.23.53.93.83.73.6-0.20.9-0.9
Cocaine induced anxiety0.30.43.7-0.3-0.6-0.30.3-0.6-0.5-0.3-0.20.30.0-0.20.1-0.1-0.1-0.0-0.5-0.00.1-0.00.2-0.3-0.21.9-1.9
Post-drug Anxiety0.30.30.70.30.10.40.6-0.00.20.20.40.70.6-0.60.60.5-0.50.6-0.90.50.60.50.70.3-0.10.7-0.7
Baseline Anxiety0.40.53.00.80.70.60.30.30.50.50.70.30.5-0.40.50.6-0.50.6-0.30.50.60.60.50.3-0.6-1.71.7
Tail length1.76.816.54.12.83.12.3-0.32.11.63.61.92.6-3.72.92.7-4.02.6-3.91.72.71.82.51.5-1.9-0.70.7
Length with tail2.39.921.44.02.93.43.1-0.32.02.14.22.83.3-4.13.63.4-4.63.3-4.52.53.62.63.42.4-2.8-1.21.2
Length without tail2.37.412.62.21.62.33.30.11.02.13.33.33.0-3.03.33.1-3.53.2-3.52.73.43.13.42.4-2.9-0.20.2
Times rat made contact with spout0.50.63.2-0.20.60.1-0.61.40.90.4-0.6-0.6-0.50.6-0.5-0.21.1-0.41.3-0.1-0.7-0.3-0.9-0.11.8-0.50.5
Lifetime Intake0.50.62.0-0.5-0.2-0.6-1.00.0-0.3-0.4-0.4-1.2-0.70.3-0.8-0.60.5-0.71.2-0.5-0.9-0.6-0.8-0.20.3-1.41.4
Liver weight, left1.01.65.51.40.30.91.4-1.2-0.00.31.51.51.2-1.81.31.1-2.21.1-2.40.71.50.71.60.7-1.40.8-0.8
Liver weight, right0.81.49.01.20.00.50.8-1.8-0.5-0.21.20.60.9-1.50.90.6-2.00.7-2.10.11.10.31.10.2-3.00.3-0.3
Locomotor activity1.42.24.82.21.61.81.40.31.50.81.51.41.4-2.01.51.3-1.81.4-2.01.11.30.91.21.2-0.51.7-1.7
Locomotor testing distance0.71.23.21.30.81.11.10.00.80.40.91.20.9-1.61.10.9-1.41.0-1.60.81.00.70.90.7-0.51.8-1.8
Locomotor testing rearing0.61.32.91.10.61.01.3-0.00.50.61.31.31.2-1.71.31.0-1.61.2-1.71.21.21.01.30.9-1.11.0-1.0
Locomotion in novel chamber0.10.10.3-0.20.30.30.20.50.40.5-0.10.30.00.40.30.40.30.3-0.00.20.30.20.10.00.00.5-0.5
Locomotion in novel chamber post-restriction0.91.42.10.81.21.31.41.11.21.31.41.31.2-1.21.41.4-1.11.4-1.01.41.31.41.31.4-0.0-0.30.3
Fecal boli incidents, locomotor time 10.60.92.4-1.5-1.2-1.3-0.8-0.5-1.2-0.7-0.9-0.9-1.00.9-1.0-0.91.0-1.01.2-0.9-0.9-0.7-0.8-0.6-0.1-0.80.8
Change in fecal boli incidents, locomotor task1.71.74.11.90.81.11.3-0.50.50.51.51.11.5-1.71.31.0-1.91.1-2.01.11.40.81.50.5-1.91.1-1.1
Time >=10cm from walls, locomotor time 12.62.86.01.00.61.22.1-0.20.50.91.92.01.7-2.41.91.6-2.21.9-2.41.42.01.72.01.1-1.71.6-1.6
Bouts of movement, locomotor time 10.20.30.6-0.6-0.4-0.4-0.5-0.2-0.2-0.4-0.8-0.3-0.60.7-0.5-0.40.7-0.60.4-0.7-0.5-0.6-0.6-0.20.30.5-0.5
Total resting periods, locomotor time 10.20.30.5-0.5-0.5-0.4-0.5-0.3-0.3-0.5-0.7-0.4-0.70.6-0.5-0.40.6-0.60.3-0.7-0.5-0.7-0.6-0.40.00.3-0.3
Rest time, locomotor task time 10.20.30.6-0.5-0.5-0.4-0.6-0.7-0.5-0.7-0.5-0.7-0.70.5-0.4-0.50.3-0.40.1-0.8-0.5-0.6-0.7-0.50.0-0.10.1
Distance moved, locomotor task time 10.71.12.11.51.11.11.20.81.01.11.31.21.4-1.01.11.1-1.21.1-0.91.21.11.11.20.8-0.10.2-0.2
Vertical activity count, locomotor time 11.02.44.21.51.51.61.71.41.51.61.71.71.9-1.41.61.7-1.51.6-1.12.11.61.81.91.8-0.10.4-0.4
Time >=10cm from walls, locomotor time 21.62.46.01.71.11.41.6-0.20.70.92.21.41.8-2.41.71.6-2.41.7-2.11.41.81.51.70.9-1.2-0.50.5
Bouts of movement, locomotor time 20.10.20.60.80.70.70.10.20.70.20.30.10.5-0.50.30.2-0.40.3-0.60.10.30.10.10.6-0.20.4-0.4
Total resting periods, locomotor time 20.10.10.40.60.40.4-0.3-0.30.4-0.20.0-0.30.2-0.20.1-0.2-0.2-0.0-0.5-0.30.0-0.3-0.20.3-0.40.4-0.4
Rest time, locomotor task time 20.60.72.5-1.0-1.3-0.9-0.4-1.6-1.4-1.1-0.7-0.3-0.70.5-0.4-0.70.2-0.5-0.4-0.9-0.3-0.7-0.4-0.5-1.31.1-1.1
Distance moved, locomotor task time 21.01.21.91.11.21.01.11.31.01.31.31.01.2-0.81.01.3-0.91.1-0.21.30.91.41.10.70.6-1.41.4
Vertical activity count, locomotor time 20.91.32.11.11.21.01.11.00.91.01.51.01.3-1.01.11.4-1.21.2-0.51.41.01.31.31.00.0-1.21.2
Light reinforcement 10.71.63.70.80.50.91.80.80.71.21.01.91.4-1.51.31.2-1.01.3-1.31.71.41.51.60.5-0.21.6-1.6
Light reinforcement 20.40.51.30.3-0.00.31.1-0.1-0.10.50.91.20.9-0.80.70.7-0.90.8-1.01.00.91.01.1-0.1-0.40.5-0.5
Bone: marrow area1.83.911.42.71.11.71.9-1.50.40.62.51.72.1-2.52.01.7-3.21.9-3.41.12.11.42.11.0-3.3-0.70.7
Bone: maximum diameter0.40.74.30.1-0.9-0.6-0.5-2.1-1.2-1.1-0.2-0.6-0.50.3-0.3-0.6-0.4-0.3-0.8-1.1-0.2-0.8-0.3-0.8-1.6-0.50.5
Bone: maximum force1.01.72.71.01.21.31.60.91.01.41.41.61.4-1.21.51.5-1.21.5-1.21.61.51.61.51.5-0.8-0.10.1
Bone: maximum moment0.61.01.70.80.91.01.20.60.71.11.21.21.1-1.01.21.2-1.01.2-0.91.21.21.31.21.2-0.7-0.50.5
Mean time between licks in bursts0.81.96.4-0.6-1.6-1.3-1.4-2.5-1.8-2.0-1.1-1.3-1.40.5-1.1-1.50.3-1.3-0.2-1.8-1.0-1.7-1.1-1.7-1.50.8-0.8
Mean num. licks in bursts0.50.85.00.11.30.70.22.21.51.20.20.00.3-0.00.30.60.50.41.00.90.20.70.20.91.7-1.11.1
Cd content in liver0.40.42.1-1.1-0.9-0.9-0.10.0-0.9-0.3-0.3-0.1-0.10.5-0.4-0.40.4-0.21.00.3-0.20.30.20.00.2-1.41.4
Co content in liver1.41.63.21.01.11.11.61.31.01.41.41.51.5-1.31.31.4-1.01.4-0.71.81.31.71.71.40.3-0.20.2
Cu content in liver0.50.63.5-0.60.2-0.2-0.61.30.50.2-0.8-0.4-0.50.9-0.6-0.31.2-0.61.4-0.2-0.7-0.4-0.70.01.90.2-0.2
Fe content in liver0.40.41.30.00.70.60.81.10.70.90.40.80.5-0.30.60.8-0.00.70.00.90.60.90.60.80.9-0.20.2
K content in liver1.31.22.1-1.4-1.2-1.2-1.0-0.7-1.1-1.0-1.4-1.0-1.30.9-1.0-1.11.5-1.11.0-1.2-1.2-1.0-1.2-1.00.90.8-0.8
Mg content in liver1.91.94.0-1.4-1.9-1.5-1.3-2.0-1.8-1.7-1.4-1.1-1.50.7-1.2-1.50.9-1.40.2-1.6-1.3-1.6-1.1-1.3-0.61.5-1.5
Mn content in liver1.11.26.1-0.9-1.7-1.3-0.6-2.5-2.0-1.5-0.7-0.6-1.00.2-0.6-0.80.0-0.8-0.5-1.2-0.5-0.9-0.4-1.2-1.70.2-0.2
Na content in liver0.30.32.00.20.50.40.10.80.80.4-0.20.2-0.1-0.10.10.20.50.10.20.1-0.00.0-0.30.21.41.1-1.1
Rb content in liver0.50.52.0-1.4-1.1-1.0-0.6-0.7-1.2-0.8-0.7-0.6-0.70.5-0.7-0.80.6-0.70.6-0.6-0.6-0.5-0.4-0.6-0.2-0.20.2
Se content in liver0.81.04.40.1-0.9-0.7-1.1-2.1-1.1-1.6-0.5-1.1-0.8-0.0-0.9-1.1-0.3-1.1-0.5-1.3-0.9-1.5-0.9-1.2-0.80.4-0.4
Sr content in liver0.20.21.7-0.2-0.3-0.30.1-0.7-0.6-0.40.1-0.0-0.1-0.10.1-0.1-0.40.2-0.1-0.0-0.00.20.0-0.20.2-1.31.3
Zn content in liver0.20.20.9-0.1-0.7-0.6-0.2-0.9-0.8-0.6-0.1-0.2-0.2-0.2-0.3-0.4-0.3-0.4-0.1-0.3-0.2-0.30.1-0.3-0.9-0.30.3
Bone: minimum diameter0.40.74.30.6-0.30.10.3-1.7-0.7-0.40.80.40.4-0.50.60.3-1.30.6-1.7-0.10.70.20.70.2-2.1-0.30.3
Time in familiar zone, hab. session 11.81.75.7-1.3-0.3-0.9-1.31.10.0-0.3-1.6-1.3-1.41.9-1.3-1.02.2-1.22.4-1.0-1.4-0.9-1.5-0.42.1-0.80.8
Time in novel zone, hab. session 11.91.95.21.70.71.21.5-0.70.40.51.71.31.6-1.91.41.2-2.21.3-2.31.21.51.01.60.6-1.70.6-0.6
Total zone transitions, hab. session 10.50.81.7-0.9-0.9-0.9-0.7-0.5-0.7-0.8-1.0-0.5-0.90.9-0.8-0.90.9-0.80.6-0.8-0.9-0.8-0.9-0.70.81.3-1.3
Total locomotion distance, hab. session 10.81.12.2-1.5-1.2-1.1-1.0-0.6-1.0-0.9-1.3-0.8-1.21.1-1.0-1.01.3-1.00.8-1.0-1.0-1.0-1.0-1.00.81.2-1.2
Locomotion velocity, hab. session 10.50.71.2-1.0-0.9-0.8-0.8-0.4-0.6-0.7-1.0-0.6-0.90.8-0.7-0.80.9-0.80.6-0.8-0.8-0.8-0.8-0.80.81.1-1.1
Time in familiar zone, hab. session 20.80.84.40.40.80.80.71.41.20.90.10.90.4-0.50.60.60.20.6-0.10.60.40.60.40.81.02.1-2.1
Time in novel zone, hab. session 20.50.55.30.50.20.0-0.0-0.5-0.2-0.10.5-0.40.3-0.3-0.00.1-0.60.0-0.10.10.1-0.00.1-0.4-0.7-2.32.3
Total zone transitions, hab. session 20.40.54.0-1.0-0.6-0.40.10.1-0.3-0.1-0.50.4-0.40.3-0.0-0.10.60.00.0-0.0-0.10.1-0.1-0.10.62.0-2.0
Total locomotion distance, hab. session 21.21.65.1-2.2-1.6-1.4-0.8-0.4-1.2-0.9-1.6-0.4-1.41.2-1.0-1.01.6-0.90.9-0.9-1.0-0.7-1.0-1.00.52.1-2.1
Locomotion velocity, hab. session 21.72.36.2-2.5-2.0-1.7-1.2-0.8-1.5-1.2-1.8-0.8-1.71.4-1.3-1.31.8-1.31.1-1.2-1.3-1.1-1.4-1.30.52.1-2.1
Novel to familiar place preference ratio0.20.21.0-0.1-0.2-0.3-0.4-0.3-0.3-0.4-0.3-0.8-0.30.1-0.5-0.40.1-0.50.5-0.4-0.5-0.5-0.5-1.00.1-0.90.9
Novelty place preference0.20.20.80.20.1-0.1-0.3-0.3-0.1-0.3-0.1-0.7-0.2-0.2-0.3-0.3-0.2-0.40.2-0.4-0.4-0.4-0.4-0.9-0.1-0.90.9
Time in novel zone, NPP test0.20.20.90.50.30.1-0.2-0.20.1-0.20.1-0.6-0.0-0.2-0.2-0.1-0.4-0.20.1-0.3-0.2-0.3-0.3-0.8-0.2-1.01.0
Total zone transitions, NPP test2.02.95.3-2.3-2.1-2.1-1.7-1.1-1.9-1.8-2.0-1.5-1.92.0-1.8-1.81.9-1.81.6-1.6-1.8-1.5-1.7-1.60.70.6-0.6
Total locomotion distance, NPP test2.23.08.6-2.9-2.3-2.3-1.7-1.0-2.1-1.6-2.0-1.4-1.92.1-1.8-1.72.0-1.71.9-1.4-1.7-1.3-1.6-1.40.5-0.10.1
Locomotion velocity, NPP test3.04.311.9-3.5-2.8-2.7-2.0-1.2-2.5-1.9-2.4-1.6-2.32.3-2.1-2.12.4-2.02.2-1.7-2.1-1.6-2.0-1.80.70.3-0.3
Intraocular pressure0.20.31.2-0.7-0.2-0.4-0.40.7-0.00.1-0.6-0.4-0.20.4-0.5-0.40.8-0.31.0-0.2-0.4-0.1-0.2-0.11.1-0.80.8
Delta distance traveled before/after self-admin1.81.96.52.62.01.91.20.91.91.31.61.01.7-1.51.31.4-1.51.2-1.30.91.30.81.11.0-0.8-0.40.4
Delta ambulatory time before/after self-admin1.51.96.12.51.91.91.20.71.71.21.61.01.7-1.61.41.4-1.61.2-1.50.91.30.81.21.1-1.00.1-0.1
Parametrial fat weight1.12.65.80.31.11.32.22.11.32.11.32.41.7-1.31.81.9-0.62.0-0.82.21.82.41.81.50.50.6-0.6
Pavlov. Cond. lever latency6.07.511.42.32.92.93.23.33.13.42.63.23.0-2.62.93.0-2.03.0-1.63.42.93.33.03.10.60.7-0.7
Pavlov. Cond. magazine entry latency1.72.24.6-0.6-1.1-1.2-1.9-1.8-1.2-1.8-1.3-2.0-1.71.5-1.6-1.61.0-1.70.7-2.1-1.7-2.1-1.9-1.80.1-0.10.1
Pavlov. Cond. change in total contacts0.70.71.8-0.1-0.5-0.6-1.1-1.3-0.7-1.1-0.5-1.2-0.80.6-0.9-0.80.2-1.00.1-1.2-0.9-1.4-0.9-1.0-0.4-0.10.1
Pavlov. Cond. index score4.05.18.5-1.8-2.2-2.2-2.7-2.8-2.4-2.8-2.1-2.7-2.62.4-2.4-2.41.6-2.41.2-2.9-2.4-2.8-2.6-2.5-0.4-0.50.5
Pavlov. Cond. latency score4.25.39.0-1.8-2.3-2.3-2.7-2.9-2.5-2.9-2.1-2.8-2.62.5-2.4-2.51.6-2.51.1-3.0-2.4-2.9-2.6-2.6-0.5-0.40.4
Pavlov. Cond. lever contacts4.95.910.1-2.4-2.8-2.7-2.7-3.2-3.1-3.0-2.2-2.7-2.72.3-2.5-2.61.6-2.61.3-2.8-2.4-2.8-2.4-2.6-0.9-0.60.6
Pavlov. Cond. magazine entry number1.41.73.60.61.01.11.61.61.11.61.21.71.4-1.31.41.4-0.91.5-0.71.91.51.91.61.6-0.00.1-0.1
Pavlov. Cond. intertrial magazine entries0.20.31.7-0.40.1-0.00.41.30.30.70.10.40.4-0.3-0.00.20.20.10.90.80.20.60.50.60.8-0.10.1
Pavlov. Cond. lever-magazine prob. diff.4.25.28.4-1.8-2.2-2.2-2.7-2.8-2.4-2.7-2.1-2.8-2.62.4-2.4-2.41.7-2.51.3-2.9-2.4-2.8-2.6-2.6-0.3-0.60.6
Pavlov. Cond. response bias2.73.35.9-1.3-1.8-1.8-2.1-2.3-1.9-2.2-1.6-2.2-2.01.6-2.0-1.91.2-2.10.9-2.4-1.9-2.4-2.0-2.2-0.3-0.30.3
Pavlov. Cond. lever latency0.30.41.60.3-0.30.10.7-0.7-0.4-0.10.60.60.6-0.80.60.3-1.00.5-1.10.40.60.50.7-0.0-1.30.7-0.7
Pavlov. Cond. magazine entry latency0.50.61.6-0.5-0.7-0.8-0.9-0.9-0.9-0.8-0.6-0.9-0.80.6-0.8-0.80.4-0.70.5-0.9-0.7-0.8-0.8-0.6-0.4-1.31.3
Pavlov. Cond. change in total contacts0.10.20.40.30.60.3-0.50.40.60.1-0.2-0.6-0.30.5-0.3-0.10.3-0.20.5-0.3-0.3-0.4-0.40.20.6-0.50.5
Pavlov. Cond. index score0.30.41.0-0.2-0.0-0.3-0.9-0.1-0.1-0.3-0.5-0.8-0.60.8-0.6-0.50.7-0.60.7-0.7-0.7-0.7-0.7-0.10.4-1.01.0
Pavlov. Cond. latency score0.20.20.9-0.00.1-0.1-0.60.10.1-0.1-0.3-0.6-0.40.7-0.4-0.30.5-0.40.6-0.5-0.4-0.5-0.50.10.4-0.90.9
Pavlov. Cond. lever contacts0.20.31.7-0.20.3-0.0-0.60.70.40.2-0.5-0.4-0.50.7-0.4-0.20.9-0.40.9-0.3-0.5-0.4-0.60.11.3-0.60.6
Pavlov. Cond. magazine entry number0.20.20.70.40.40.40.50.40.50.30.30.40.4-0.50.40.3-0.40.4-0.40.40.40.30.40.00.30.9-0.9
Pavlov. Cond. intertrial magazine entries0.30.53.10.1-0.5-0.3-0.4-0.9-0.4-0.8-0.4-0.4-0.2-0.1-0.4-0.6-0.0-0.6-0.4-0.7-0.5-0.9-0.4-0.8-0.41.8-1.8
Pavlov. Cond. lever-magazine prob. diff.0.20.31.0-0.3-0.0-0.3-0.8-0.1-0.1-0.3-0.5-0.8-0.60.8-0.6-0.40.6-0.50.7-0.6-0.6-0.6-0.7-0.10.3-1.01.0
Pavlov. Cond. response bias0.50.71.2-0.6-0.3-0.6-1.1-0.1-0.3-0.5-0.9-0.9-1.01.0-0.9-0.71.1-0.81.1-0.9-0.9-0.9-1.0-0.30.8-0.80.8
Time in closed arm before self-admin0.10.10.40.70.20.20.2-0.40.0-0.00.30.20.3-0.00.20.1-0.30.1-0.4-0.00.2-0.00.2-0.2-0.60.7-0.7
Time in closed arm after self-admin0.10.10.3-0.5-0.2-0.2-0.2-0.3-0.4-0.20.0-0.20.00.30.0-0.10.0-0.0-0.0-0.10.00.20.10.2-0.0-0.60.6
Time in open arm before self-admin0.70.71.5-0.1-0.4-0.6-1.2-0.6-0.4-0.9-0.7-1.2-0.80.6-1.0-0.90.5-1.00.7-1.0-0.9-1.2-1.1-0.80.2-1.21.2
Time in open arm after self-admin0.20.20.80.40.1-0.1-0.4-0.10.1-0.2-0.4-0.5-0.40.3-0.5-0.30.1-0.50.4-0.6-0.5-0.7-0.6-0.7-0.5-0.90.9
Bone: periosteal estimation1.12.46.82.11.11.51.5-0.70.70.81.91.41.6-1.71.81.5-2.31.7-2.60.91.81.21.61.0-2.2-0.40.4
Bone: periosteal perimeter0.30.52.30.90.20.50.4-1.1-0.1-0.10.80.50.4-0.60.70.5-1.10.6-1.50.10.70.20.60.4-1.2-0.30.3
Bone: post-yield work0.30.53.2-0.1-0.9-0.60.0-1.7-1.2-0.90.10.0-0.1-0.2-0.1-0.3-0.6-0.1-0.8-0.30.0-0.10.1-0.4-1.8-0.10.1
Progressive ratio test 1 active lever presses0.40.52.5-0.3-0.5-0.7-0.7-0.5-0.7-0.6-0.3-0.9-0.60.4-0.7-0.50.3-0.60.8-0.4-0.6-0.4-0.6-0.2-0.2-1.61.6
Progressive ratio test 1 breakpoint0.40.42.4-0.3-0.4-0.6-0.7-0.5-0.7-0.6-0.2-0.9-0.50.3-0.6-0.50.2-0.50.7-0.4-0.6-0.4-0.6-0.2-0.3-1.61.6
Progressive ratio test 1 inactive lever presses0.10.10.3-0.6-0.3-0.30.20.5-0.20.1-0.20.2-0.00.1-0.10.10.50.00.60.5-0.10.5-0.00.20.50.2-0.2
Progressive ratio test 2 active lever presses0.50.61.4-0.9-0.7-0.9-0.9-0.1-0.6-0.5-0.9-0.9-0.90.9-0.9-0.71.0-0.91.2-0.8-1.0-0.7-0.9-0.80.5-0.40.4
Progressive ratio test 2 breakpoint0.60.71.6-0.9-0.6-0.8-0.9-0.0-0.5-0.5-0.9-0.9-1.00.9-1.0-0.81.1-0.91.3-0.8-1.0-0.7-0.9-0.80.6-0.50.5
Progressive ratio test 2 inactive lever presses0.71.12.1-0.5-1.2-1.3-0.9-1.4-1.5-1.3-0.8-1.2-0.90.6-1.1-1.10.5-1.10.8-1.0-1.1-1.0-1.0-1.2-0.8-1.21.2
Incentive Sensitization - Responses0.40.50.9-0.6-0.6-0.7-0.7-0.2-0.4-0.5-0.9-0.5-0.80.7-0.8-0.70.8-0.80.7-0.9-0.9-0.8-0.8-1.00.50.7-0.7
Incentive Sensitization - Breakpoint0.40.61.0-0.7-0.6-0.7-0.7-0.1-0.4-0.5-1.0-0.5-0.80.8-0.8-0.71.0-0.80.8-0.8-0.9-0.8-0.8-0.90.70.7-0.7
Sum of active levers in priming session hrs 5-60.30.20.60.0-0.3-0.4-0.7-0.8-0.5-0.7-0.3-0.8-0.40.3-0.5-0.60.0-0.60.2-0.7-0.6-0.7-0.6-0.0-0.10.1-0.1
Progressive ratio5.28.211.23.03.23.33.02.73.33.23.03.13.1-2.73.33.2-2.53.3-2.53.13.13.22.83.10.30.9-0.9
Food seeking constrained by brief footshock0.10.10.70.20.50.2-0.20.60.40.30.2-0.10.10.3-0.10.20.2-0.10.5-0.0-0.0-0.0-0.1-0.10.8-0.60.6
Seeking ratio, punishment vs. effort3.24.66.7-1.8-2.2-2.4-2.4-2.1-2.3-2.4-2.1-2.5-2.32.0-2.5-2.31.7-2.61.9-2.5-2.3-2.6-2.1-2.5-0.0-0.50.5
Retroperitoneal fat weight0.00.10.6-0.7-0.2-0.20.50.5-0.20.40.10.80.2-0.10.20.40.20.40.20.60.30.60.20.30.3-0.10.1
Reaction time number correct0.81.53.21.31.41.31.61.81.61.50.91.41.3-1.11.21.3-0.61.2-0.41.51.11.31.21.00.60.1-0.1
Reaction time mean minus median1.12.64.3-1.8-1.9-1.8-2.0-2.1-2.0-2.0-1.3-2.0-1.81.4-1.7-1.91.2-1.60.9-2.0-1.7-1.8-1.6-1.40.0-0.50.5
Reaction time mean minus median AUC1.84.57.0-2.3-2.4-2.4-2.6-2.4-2.6-2.6-1.8-2.7-2.31.7-2.2-2.31.5-2.21.6-2.3-2.2-2.2-2.1-1.8-0.0-1.61.6
Reaction time num false alarms0.10.21.10.30.00.2-0.1-0.60.0-0.20.20.10.2-0.60.2-0.0-0.50.1-0.8-0.10.3-0.10.30.0-0.71.1-1.1
Reaction time num false alarms AUC0.30.52.40.90.50.70.2-0.40.50.10.50.40.5-1.00.60.3-0.90.4-1.20.10.60.10.60.3-0.71.5-1.5
Reaction time trials correct on left0.81.53.21.31.41.31.61.81.61.50.91.41.3-1.11.21.3-0.61.2-0.41.51.11.31.21.00.60.1-0.1
Reaction time trials on left0.71.42.91.31.41.31.61.71.51.50.91.31.3-1.11.11.3-0.71.1-0.41.51.11.31.11.00.50.1-0.1
Reaction time mean2.03.27.1-2.2-2.4-2.2-1.9-2.6-2.7-2.3-1.3-1.8-1.81.5-1.6-1.81.0-1.60.8-1.9-1.5-1.6-1.5-1.5-1.0-1.61.6
Reaction time mean AUC2.03.26.8-2.2-2.3-2.2-1.9-2.5-2.6-2.2-1.3-1.8-1.81.5-1.6-1.81.1-1.60.9-1.8-1.6-1.6-1.5-1.4-0.8-1.71.7
Median of all reaction times1.52.25.3-1.9-2.0-1.8-1.4-2.2-2.3-1.8-1.0-1.3-1.41.3-1.2-1.40.7-1.20.6-1.4-1.1-1.1-1.1-1.1-1.2-1.71.7
Reaction time omissions1.11.63.4-1.8-1.8-1.6-1.4-1.8-1.8-1.7-1.0-1.1-1.41.1-1.2-1.20.9-1.20.4-1.2-1.2-1.2-1.1-1.0-0.60.0-0.0
Reaction time false alarm rate0.30.52.20.1-0.4-0.2-0.8-1.5-0.5-0.9-0.1-0.6-0.3-0.3-0.2-0.5-0.4-0.4-0.8-0.9-0.2-0.8-0.2-0.3-1.21.1-1.1
Reaction time premature initiation rate0.10.10.30.20.20.20.50.10.10.30.30.30.50.00.40.4-0.20.4-0.30.40.40.40.3-0.3-0.4-0.20.2
Reaction time premature initiations0.71.22.51.11.21.21.61.21.21.41.01.21.3-0.81.21.3-0.81.2-0.71.41.21.31.10.4-0.00.0-0.0
Std. dev. reaction times1.42.56.2-1.3-1.8-1.7-2.0-2.5-2.0-2.2-1.1-2.0-1.71.2-1.5-1.70.8-1.50.5-2.0-1.5-1.8-1.5-1.3-0.7-0.90.9
Reaction time trials completed0.71.42.91.31.41.31.61.71.51.50.91.31.3-1.11.11.3-0.71.1-0.41.51.11.31.11.00.50.1-0.1
Reaction time trials AUC0.71.32.81.21.31.21.61.71.41.50.91.41.3-1.11.11.3-0.61.1-0.41.51.11.31.11.00.50.2-0.2
Run reversals in cocaine runway, females0.10.10.6-0.50.1-0.1-0.20.60.10.4-0.1-0.1-0.20.4-0.00.00.50.10.70.1-0.10.40.20.20.2-0.80.8
Run reversals in cocaine runway, males0.80.81.4-0.8-1.0-0.9-0.9-1.1-1.0-1.1-1.0-1.0-1.10.9-0.8-1.00.6-0.90.4-1.2-0.8-1.0-0.9-1.1-0.50.4-0.4
Latency to leave start box in cocaine runway0.80.92.5-1.1-1.5-1.2-0.7-1.6-1.6-1.4-0.7-0.7-0.90.9-0.8-0.90.5-0.90.3-1.0-0.8-0.9-0.7-1.2-0.7-0.40.4
Latency to leave start box in cocaine runway, F0.80.92.2-1.2-1.4-1.3-0.8-1.3-1.5-1.5-0.7-0.8-0.90.6-0.9-1.00.5-1.00.5-0.9-0.9-0.9-0.7-0.8-0.2-0.60.6
Latency to leave start box in cocaine runway, M0.10.10.6-0.2-0.3-0.10.1-0.6-0.4-0.1-0.10.2-0.20.50.20.10.10.1-0.4-0.30.2-0.1-0.0-0.5-0.80.4-0.4
Std. dev. time between licks in bursts0.81.16.70.1-1.1-0.7-0.8-2.6-1.4-1.5-0.4-0.6-0.60.4-0.4-0.8-0.3-0.6-1.1-1.4-0.3-1.2-0.4-0.9-2.10.8-0.8
Total sessions with >9 infusions0.20.31.80.00.3-0.0-0.80.10.2-0.20.1-1.1-0.2-0.4-0.4-0.3-0.1-0.30.6-0.1-0.4-0.2-0.40.30.4-1.31.3
Short access day 1 total inactive lever presses0.60.82.0-0.5-0.9-1.0-0.9-1.4-1.3-1.3-0.3-1.1-0.60.0-0.9-0.8-0.0-0.90.4-0.7-0.9-0.9-0.7-0.3-1.0-1.01.0
Short access day 10 total inactive lever presses0.20.65.4-0.6-0.8-0.50.3-0.4-0.5-0.4-0.50.50.1-0.3-0.2-0.40.2-0.2-0.30.0-0.2-0.2-0.3-0.40.32.3-2.3
Short access day 1 total infusions0.70.92.9-0.3-0.6-0.8-1.3-0.8-0.8-1.0-0.4-1.7-0.7-0.0-1.0-1.00.3-1.00.9-0.7-1.0-0.9-1.0-0.8-0.4-1.71.7
Short access day 10 total infusions0.40.51.4-0.8-0.4-0.7-1.00.0-0.5-0.6-0.5-1.2-0.60.1-0.9-0.80.6-0.81.2-0.2-0.9-0.5-0.90.10.8-0.70.7
Short access total infusions0.60.82.8-0.7-0.5-0.8-1.3-0.4-0.7-0.8-0.4-1.6-0.80.1-1.0-0.90.4-0.91.2-0.5-1.0-0.7-0.9-0.10.2-1.71.7
Short access day 1 locomotion0.70.91.5-1.2-1.1-1.1-1.2-0.8-1.0-1.1-0.9-1.1-1.10.2-1.0-1.10.7-1.00.7-0.9-1.0-1.0-1.1-0.6-0.10.3-0.3
Short access day 10 total locomotion1.63.06.62.31.41.81.7-0.11.21.12.01.61.8-2.41.91.7-2.41.8-2.61.22.01.31.91.4-1.81.1-1.1
Short access total locomotion0.20.31.30.40.10.20.1-0.6-0.1-0.10.70.00.3-1.10.40.3-1.00.4-0.80.30.50.20.60.5-1.1-0.40.4
One hour access (0.3 mA shock)1.51.72.6-1.3-1.3-1.4-1.2-0.5-1.0-1.1-1.6-1.1-1.41.3-1.4-1.41.6-1.41.3-1.5-1.4-1.4-1.5-1.30.71.4-1.4
Compulsive drug intake1.51.810.1-1.1-1.8-1.1-0.2-1.7-1.6-1.3-1.10.0-0.70.7-0.5-0.90.7-0.5-0.6-1.1-0.3-0.7-0.5-1.5-0.93.2-3.2
One hour access (shock baseline)0.40.62.4-0.40.2-0.3-0.80.80.20.1-0.5-1.0-0.60.6-0.7-0.40.8-0.71.5-0.4-0.8-0.5-0.70.11.0-1.51.5
Social response proportion0.80.92.61.20.50.80.8-0.50.20.21.10.60.9-1.01.00.7-1.40.9-1.40.81.00.71.00.6-1.6-1.01.0
Social responses0.81.02.41.41.01.21.00.10.80.51.20.91.0-1.31.21.0-1.41.1-1.60.91.10.81.00.9-0.4-0.10.1
Social time0.91.26.4-0.7-1.3-0.7-0.4-1.8-1.2-1.3-0.5-0.0-0.6-0.3-0.2-0.8-0.2-0.4-1.1-0.8-0.2-0.8-0.1-0.7-1.62.5-2.5
Soleus weight0.61.812.40.9-0.9-0.10.4-3.1-1.6-1.10.90.20.6-1.50.50.0-2.10.3-2.5-0.50.7-0.20.9-0.5-3.50.1-0.1
Bone: stiffness0.71.12.40.70.81.01.51.10.91.20.91.61.1-1.01.11.2-0.71.2-0.81.31.21.31.21.1-0.30.7-0.7
Tibialis anterior weight0.10.52.00.10.80.70.61.41.01.00.20.80.4-0.50.70.70.10.70.10.60.60.70.50.60.50.8-0.8
Time to tail flick, vehicle, before self-admin0.70.76.6-0.9-0.3-0.00.30.50.20.2-0.40.8-0.10.40.30.10.50.3-0.30.40.20.40.40.50.52.6-2.6
Time to tail flick, vehicle, after self-admin0.30.41.2-0.3-0.6-0.6-0.7-0.8-0.6-0.8-0.4-0.7-0.40.3-0.6-0.60.3-0.60.2-0.6-0.5-0.7-0.5-0.2-0.1-1.11.1
Time to tail flick, test, before self-admin0.40.42.70.40.60.50.40.90.90.5-0.20.40.10.10.20.10.40.20.00.20.20.1-0.10.51.01.6-1.6
Time to tail flick, test, after self-admin2.12.24.0-1.1-1.1-1.4-1.5-0.4-0.9-1.3-1.9-1.4-1.61.9-1.7-1.71.9-1.61.7-1.7-1.8-1.7-2.0-1.41.4-0.10.1
Delta time to tail flick, vehicle, before/after SA2.12.06.8-0.8-0.8-1.2-1.6-0.7-1.0-1.0-1.0-1.8-1.11.1-1.5-1.21.1-1.51.7-1.2-1.5-1.4-1.6-0.90.6-2.62.6
Delta time to tail flick, test, before/after SA1.01.12.1-1.5-1.2-1.3-1.0-0.4-1.2-0.9-1.1-0.8-1.11.3-1.1-1.01.3-1.01.2-0.8-1.1-0.8-1.0-1.00.5-0.80.8
Tibia length1.33.510.12.21.11.72.1-0.80.71.02.11.92.1-2.52.01.8-2.71.8-3.21.32.01.42.10.9-2.60.9-0.9
Ambulatory time before self-admin0.10.10.4-0.6-0.5-0.4-0.2-0.2-0.4-0.3-0.3-0.1-0.50.1-0.1-0.30.1-0.1-0.0-0.1-0.20.0-0.2-0.50.30.3-0.3
Ambulatory time after self-admin1.21.42.61.61.21.41.20.41.20.91.31.21.3-1.51.41.2-1.51.3-1.60.91.31.01.30.7-0.90.8-0.8
Bone: tissue strength0.10.11.2-0.1-0.0-0.10.1-0.0-0.20.10.40.10.3-0.10.10.2-0.40.20.00.40.20.40.30.3-0.5-1.11.1
Total heroin consumption0.10.11.30.3-0.00.10.1-0.10.1-0.00.10.20.1-0.40.10.0-0.10.0-0.50.10.1-0.20.0-0.10.21.2-1.2
Bone: trabecular number2.13.57.3-2.6-1.9-2.1-1.90.1-1.3-1.2-2.4-1.8-2.02.6-2.1-2.02.7-2.02.6-1.4-2.0-1.5-1.9-1.61.20.9-0.9
Bone: trabecular spacing2.93.97.82.62.02.22.00.11.51.42.61.72.1-2.52.12.1-2.82.1-2.61.72.11.81.91.6-1.3-1.21.2
Bone: trabecular thickness1.51.94.9-2.2-1.4-1.5-1.20.2-1.0-0.7-1.8-1.0-1.42.1-1.3-1.32.2-1.32.0-1.0-1.3-0.9-1.3-1.11.00.5-0.5
Bone: trabecular tissue density0.10.21.31.10.70.50.1-0.10.6-0.00.3-0.30.3-0.60.10.1-0.50.1-0.2-0.3-0.0-0.2-0.1-0.00.1-0.80.8
Water consumed over 24 hours0.00.10.40.1-0.2-0.00.1-0.6-0.3-0.20.10.1-0.0-0.20.10.0-0.30.0-0.5-0.20.0-0.1-0.0-0.2-0.60.2-0.2
Number of responses in last shaping day0.70.74.21.10.30.5-0.1-1.4-0.2-0.50.8-0.50.3-0.50.50.2-1.30.3-1.2-0.50.5-0.10.6-0.3-2.1-1.41.4