Hub : Genes

Tap1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Tap1 0.32 0.1 0.0e+00 0.34 0.38 0.36 0.37 2.6e-39 5.6e-44 2.4e-42 4.4e-43
2 Adipose gene expression Tap1 0.17 0.08 3.3e-16 0.16 0.14 0.15 0.15 6.7e-18 1.7e-15 4.4e-16 1.3e-16
3 Eye gene expression Tap1 0.51 0.16 4.1e-04 0.09 0.06 0.01 0.07 1.8e-02 4.0e-02 2.5e-01 3.4e-02
4 IL gene expression Tap1 0.21 0.11 3.2e-03 0.06 0.08 0.05 0.1 1.7e-02 5.0e-03 2.6e-02 2.1e-03
5 NAcc gene expression Tap1 0.16 0.06 0.0e+00 0.19 0.18 0.18 0.19 2.1e-28 3.9e-27 2.8e-27 1.4e-27
6 IC gene expression Tap1 0.2 0.1 2.0e-05 0.08 0.08 0.06 0.08 2.2e-04 3.0e-04 1.2e-03 3.6e-04
7 Brain gene expression Tap1 0.11 0.05 1.4e-09 0.1 0.09 0.1 0.1 7.2e-10 8.2e-09 3.1e-09 3.2e-09
8 PL gene expression Tap1 0.29 0.11 0.0e+00 0.25 0.27 0.29 0.28 9.4e-27 6.0e-29 9.1e-32 8.3e-31
9 Adipose mRNA stability Tap1 0.04 0.03 1.1e-04 0.01 0.04 0.02 0.02 1.1e-02 8.6e-05 4.7e-03 2.0e-03
10 BLA gene expression Tap1 0.43 0.12 0.0e+00 0.27 0.38 0.38 0.38 1.7e-14 2.0e-21 2.4e-21 1.3e-21
11 pVTA gene expression Tap1 0.16 0.07 3.1e-11 0.1 0.14 0.11 0.12 1.2e-08 3.7e-11 2.3e-09 1.5e-09
12 PL mRNA stability Tap1 0.04 0.02 1.4e-03 0 0 -0 0 2.9e-01 7.8e-02 7.7e-01 3.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.81.55.21.8-2.3-0.30.8-1.4-1.4-1.4-0.51.70.20.2-0.3
Area under the delay curve0.20.30.9-0.90.30.30.20.50.40.3-0.5-0.90.40.40.8
BMI with tail2.17.312.1-1.81.43.5-3.22.82.82.73.41.0-3.2-3.2-2.1
BMI without tail0.84.39.0-3.02.52.5-2.32.22.22.01.9-1.6-1.5-1.6-0.0
Body weight2.812.419.7-3.83.93.5-3.84.44.44.03.5-1.0-3.2-3.3-1.9
Weight adjusted by age0.61.74.5-1.62.11.0-1.31.61.61.70.9-0.6-0.8-0.9-0.6
Bone surface0.00.10.30.5-0.3-0.30.20.10.10.1-0.50.1-0.00.0-0.3
Bone volume0.10.20.90.6-1.00.00.2-0.2-0.2-0.2-0.20.6-0.1-0.1-0.2
Breakpoint value in progressive ratio session0.10.20.30.6-0.3-0.40.6-0.5-0.4-0.4-0.6-0.10.40.40.1
Number of licking bursts0.10.41.50.9-0.2-1.20.9-0.3-0.3-0.2-0.8-0.30.70.7-0.1
Context. condit. distance diff. score3.44.112.03.5-2.9-2.32.3-1.5-1.5-1.6-1.72.11.21.2-0.9
Locomotion velocity, session 12.22.54.41.2-1.0-2.02.0-1.6-1.6-1.4-2.1-0.41.71.91.2
Locomotion distance, session 10.60.82.31.4-1.5-0.50.7-1.0-1.1-0.9-0.61.10.30.4-0.0
Locomotion velocity, session 20.30.40.90.8-0.7-0.80.9-0.4-0.5-0.5-0.8-0.10.70.70.3
Locomotion distance, session 20.50.73.41.5-1.3-0.20.3-0.3-0.4-0.4-0.01.9-0.3-0.2-1.0
Locomotion velocity, session 30.20.21.0-0.5-0.10.00.0-0.4-0.40.10.0-1.00.30.41.0
Locomotion distance, session 31.31.53.01.5-1.7-0.91.1-1.7-1.7-1.3-0.90.71.00.90.5
Stereotopy head waving bouts, day 30.70.83.0-1.01.7-0.0-0.51.21.21.10.3-1.1-0.3-0.2-0.2
Stereotopy head waving duration, day 30.60.72.5-1.31.5-0.2-0.30.80.80.7-0.1-1.60.20.20.6
Locomotion velocity, session 72.62.99.82.8-2.9-0.80.9-1.5-1.5-1.0-0.43.10.10.1-1.1
Locomotion distance, session 73.74.79.83.0-3.1-1.71.9-2.8-2.8-2.2-1.52.31.41.30.2
Stereotopy head waving bouts, day 71.61.86.1-1.00.3-0.90.8-0.7-0.6-0.9-1.3-2.51.61.52.2
Stereotopy head waving duration, day 70.70.84.2-1.30.9-0.2-0.0-0.00.0-0.1-0.4-2.10.70.71.4
Locomotion velocity, session 81.01.23.61.5-0.7-1.91.8-0.5-0.5-0.3-1.5-0.11.11.2-0.1
Locomotion distance, session 82.73.914.43.8-2.9-1.71.8-1.2-1.2-1.2-0.93.10.40.4-1.8
Degree of sensitization distance0.10.10.40.60.0-0.60.50.10.00.1-0.20.40.00.1-0.5
Degree of sensitization stereotypy1.92.14.6-0.1-0.7-1.21.2-1.3-1.2-1.5-1.7-1.81.81.72.1
Conditioned locomotion1.21.42.6-0.30.90.9-1.01.61.61.61.10.4-1.3-1.3-1.4
Cocaine response after cond. corrected1.11.74.91.0-0.10.8-0.90.90.90.81.42.1-1.5-1.5-2.2
Cocaine response after cond. not corrected0.60.91.7-0.11.00.5-0.71.31.31.10.90.3-1.0-0.9-1.3
Cocaine response before conditioning2.22.712.6-2.42.5-0.2-0.11.01.01.0-0.5-3.50.70.81.7
Saline control response1.92.69.8-3.12.01.9-1.71.11.11.11.0-2.0-0.6-0.71.2
Bone: connectivity density0.71.14.61.7-1.6-0.10.3-0.6-0.6-0.6-0.02.1-0.5-0.4-1.1
Bone: cortical apparent density1.11.73.7-1.51.11.9-1.81.21.21.01.5-0.1-1.4-1.5-0.4
Bone: cortical area0.10.10.4-0.50.20.2-0.10.60.50.50.0-0.6-0.1-0.10.1
Bone: cortical porosity4.24.510.2-0.6-0.2-1.91.9-1.7-1.7-1.8-2.4-2.82.62.73.2
Bone: cortical porosity3.84.17.9-0.3-0.0-2.22.0-1.5-1.5-1.7-2.4-2.52.52.62.8
Bone: cortical thickness0.30.51.7-1.20.01.3-0.80.40.30.30.7-0.6-0.5-0.70.4
Bone: cortical thickness1.31.64.1-1.60.72.0-1.71.01.01.11.5-0.4-1.5-1.4-0.1
Bone: cortical tissue density1.01.63.3-1.51.21.8-1.81.21.21.01.4-0.2-1.3-1.4-0.4
Condit. Reinf. active minus inactive responses1.51.73.00.3-0.3-1.31.4-1.4-1.4-1.7-1.4-0.61.51.51.4
Condit. Reinf. active-inactive response ratio0.30.31.1-1.00.80.10.0-0.1-0.2-0.4-0.0-1.00.40.31.0
Condit. Reinf. active responses0.60.82.20.6-0.6-0.81.0-1.2-1.2-1.5-0.80.30.90.80.6
Condit. Reinf. inactive responses0.81.02.81.4-1.7-0.20.5-1.2-1.3-1.3-0.31.60.30.2-0.2
Incentive salience index mean1.41.83.21.7-1.3-1.71.8-1.2-1.3-1.6-1.40.71.21.20.2
Condit. Reinf. lever presses1.72.59.13.0-2.1-1.61.7-0.8-0.9-1.1-0.92.40.50.4-1.4
Condit. Reinf. active minus inactive responses0.30.52.3-1.10.8-0.20.20.20.20.4-0.1-1.50.40.50.9
Condit. Reinf. active-inactive response ratio0.30.52.0-1.01.1-0.50.30.40.50.5-0.3-1.40.40.50.6
Condit. Reinf. active responses0.20.20.9-0.60.3-0.20.3-0.4-0.3-0.0-0.2-1.00.40.50.8
Condit. Reinf. inactive responses0.10.10.4-0.4-0.00.6-0.5-0.1-0.10.10.4-0.1-0.3-0.30.2
Condit. Reinf. lever presses1.31.92.90.5-1.2-1.31.4-1.7-1.7-1.6-1.4-0.61.61.51.5
Condit. Reinf. lever reinforcers received0.40.51.3-0.40.2-0.60.6-0.7-0.6-0.3-0.6-1.20.70.91.1
Conditioned reinforcement - actives0.00.10.70.1-0.30.8-0.0-0.4-0.3-0.2-0.10.40.0-0.00.0
Conditioned reinforcement - inactives0.00.10.2-0.20.30.3-0.0-0.4-0.5-0.4-0.20.10.30.20.3
Conditioned locomotion0.10.10.20.3-0.3-0.10.3-0.4-0.3-0.3-0.40.50.30.30.0
Patch foraging indifference point 0 sec0.82.37.0-2.62.32.1-1.61.01.01.21.2-1.4-0.9-0.90.6
Patch foraging indifference point AUC0.30.73.0-0.81.1-0.60.5-0.0-0.00.1-0.5-1.70.60.81.1
Delay disc. indifference point, 0s delay0.10.10.20.2-0.10.20.20.40.40.1-0.20.40.0-0.1-0.4
Delay disc. indifference point, 16s delay0.10.20.8-0.7-0.20.5-0.10.10.00.0-0.2-0.60.30.30.9
Delay disc. indifference point, 2s delay0.50.51.4-0.81.0-0.30.70.30.20.2-1.0-1.20.80.80.7
Delay disc. indifference point, 24s delay0.50.82.6-1.40.70.10.1-0.2-0.2-0.1-0.6-1.60.90.81.5
Delay disc. indifference point, 4s delay0.90.92.5-1.61.40.8-0.21.11.00.9-0.1-1.60.00.00.6
Delay disc. indifference point, 8s delay0.10.10.4-0.5-0.2-0.00.30.20.1-0.1-0.5-0.40.40.40.6
Indifference point function ln k0.20.51.10.7-0.6-1.00.8-0.4-0.5-0.5-1.0-0.30.80.80.3
Indifference point function log k0.20.51.10.7-0.6-1.00.8-0.4-0.5-0.5-1.0-0.30.80.80.3
Patch foraging total patch changes 0 sec0.82.37.1-2.72.22.1-1.71.01.01.11.2-1.4-0.9-0.90.7
Patch foraging total patch changes 12 sec1.11.54.3-2.11.91.5-1.10.70.81.00.8-1.5-0.5-0.50.7
Patch foraging total patch changes 18 sec1.02.45.9-1.71.22.4-2.11.11.21.22.00.0-1.7-1.6-0.4
Patch foraging total patch changes 24 sec0.10.31.5-0.6-0.11.2-0.6-0.4-0.4-0.20.60.3-0.4-0.40.4
Patch foraging total patch changes 6 sec0.91.65.1-2.31.71.9-1.20.90.80.81.0-1.1-0.6-0.70.7
Patch foraging time to switch 0 sec0.93.65.70.0-0.02.3-2.11.61.61.32.42.3-2.3-2.4-2.3
Patch foraging water rate 0 sec0.10.31.2-0.91.10.1-0.40.50.50.80.5-0.5-0.3-0.3-0.0
Patch foraging water rate 12 sec0.00.00.2-0.1-0.3-0.0-0.0-0.4-0.4-0.30.10.1-0.0-0.10.3
Patch foraging water rate 18 sec0.20.40.8-0.90.40.9-0.60.40.40.70.7-0.3-0.5-0.5-0.0
Patch foraging water rate 24 sec0.10.10.5-0.50.20.7-0.50.20.20.30.4-0.2-0.4-0.40.0
Patch foraging water rate 6 sec0.20.30.7-0.50.50.6-0.70.50.50.80.8-0.0-0.7-0.6-0.2
Seeking ratio, delayed vs. immediate footshock1.11.67.4-1.92.10.9-0.40.60.50.60.2-2.70.10.11.3
Distance traveled before self-admin0.71.52.90.30.51.0-1.01.41.41.41.31.0-1.5-1.4-1.7
Distance traveled after self-admin0.91.63.5-1.41.90.7-0.91.61.61.60.8-1.4-0.9-0.8-0.2
Extensor digitorum longus weight0.00.20.60.6-0.0-0.10.10.50.50.30.10.6-0.2-0.1-0.7
Bone: elastic displacement0.50.61.9-0.5-0.4-0.30.5-0.9-0.9-0.8-0.7-0.70.90.81.4
Bone: elastic work0.10.10.5-0.70.10.2-0.20.10.10.2-0.1-0.50.00.00.4
Bone: endosteal estimation0.82.06.2-1.22.5-0.1-0.52.12.12.00.4-1.4-0.5-0.4-0.8
Bone: endosteal perimeter0.20.51.40.50.8-0.80.31.21.11.0-0.0-0.1-0.1-0.0-1.1
Epididymis fat weight2.713.834.0-2.81.35.8-5.12.92.92.64.91.9-4.4-4.6-2.1
Delta time in closed arm before/after self-admin0.70.61.0-0.30.40.9-0.80.90.91.00.60.6-0.8-0.9-1.0
Delta time in open arm before/after self-admin0.10.10.3-0.2-0.0-0.40.1-0.4-0.5-0.4-0.3-0.20.30.30.6
Diff in mean of infusions in LGA sessions0.61.14.02.0-1.7-0.50.6-0.7-0.7-0.5-0.11.9-0.1-0.1-1.0
Delay discount exponential model param0.30.41.41.0-0.5-0.2-0.3-0.4-0.3-0.20.61.2-0.6-0.5-1.0
Extinction: sum of active levers before priming0.10.20.70.8-0.1-0.80.40.00.1-0.1-0.50.40.20.2-0.5
Active lever presses in extinction session 60.20.20.70.3-0.7-0.10.1-0.5-0.7-0.4-0.10.90.10.10.1
Bone: final force2.64.36.5-2.01.72.5-2.42.22.22.32.3-0.0-2.2-2.2-1.3
Bone: final moment1.82.94.5-1.71.42.1-2.01.81.81.91.9-0.0-1.8-1.8-1.0
Food consumed during 24 hour testing period1.02.03.6-0.31.00.9-1.31.81.81.71.50.9-1.6-1.6-1.9
Glucose1.21.97.61.7-0.1-2.81.8-0.8-0.8-0.8-1.50.31.51.6-0.3
Heart weight0.81.24.1-2.01.7-0.0-0.00.80.80.9-0.2-2.00.30.41.1
Delay discount hyperbolic model param0.40.51.91.1-0.6-0.2-0.4-0.4-0.3-0.20.71.4-0.7-0.7-1.1
Intermittent access intake day 1-15 change0.00.20.9-0.50.5-0.10.10.00.20.1-0.1-0.90.20.20.5
Intermittent access intake escalation0.10.42.0-1.00.60.2-0.1-0.20.0-0.1-0.0-1.40.40.31.1
Intermittent access intake escalation 20.20.30.8-0.1-0.1-0.70.5-0.4-0.2-0.2-0.7-0.90.70.60.8
Intermitt. access day 1 inactive lever presses0.00.51.70.70.8-0.0-0.00.50.71.00.20.5-0.6-0.5-1.3
Intermitt. access day 15 inactive lever presses0.10.30.9-0.50.90.4-0.60.80.70.70.4-0.2-0.4-0.4-0.3
Intermitt. access escalation Index0.20.83.31.8-1.2-0.80.9-0.5-0.5-0.4-0.21.2-0.2-0.0-1.0
Intermittent access day 1 total infusions0.82.34.51.5-1.7-0.91.5-2.0-1.9-2.1-1.41.31.31.30.6
Intermittent access day 15 total infusions0.30.81.80.1-0.5-0.20.8-1.3-1.1-1.2-0.8-0.11.00.91.1
Intermittent access terminal intake (last 3 days)0.50.81.7-0.2-0.2-0.30.8-1.3-1.1-1.1-0.9-0.41.11.01.3
Intermittent access total infusions0.91.02.30.3-0.7-0.50.9-1.5-1.4-1.4-1.00.21.11.11.1
Intermittent access day 1 locomotion0.10.21.00.5-0.60.40.1-0.6-0.6-0.70.11.0-0.00.0-0.1
Intermittent access day 15 total locomotion0.20.61.7-1.10.91.3-0.80.80.90.90.7-0.3-0.6-0.6-0.1
Intermittent access total locomotion0.10.11.0-0.50.11.0-0.3-0.3-0.1-0.10.2-0.00.0-0.10.3
Intermittent access standard deviation0.42.04.2-2.01.91.9-1.61.21.21.31.3-0.9-1.0-1.00.0
Left kidney weight1.19.014.5-3.83.23.3-3.23.73.73.32.7-1.7-2.5-2.7-0.8
Right kidney weight1.510.215.3-3.53.33.3-3.53.93.93.63.3-0.9-3.0-3.1-1.6
Cocaine induced anxiety0.10.41.10.60.10.0-0.20.70.70.70.40.5-0.7-0.6-1.1
Post-drug Anxiety0.40.40.8-0.10.50.9-0.40.90.80.90.6-0.1-0.7-0.6-0.7
Baseline Anxiety0.10.10.4-0.70.50.7-0.10.20.20.20.1-0.4-0.1-0.00.3
Tail length0.73.914.5-2.83.7-0.5-0.31.71.81.3-0.3-3.80.70.61.2
Length with tail1.35.516.2-3.24.00.6-1.63.23.22.70.9-2.7-0.8-0.9-0.3
Length without tail2.010.519.2-2.22.92.5-3.34.44.34.13.10.5-3.3-3.3-3.0
Times rat made contact with spout0.91.13.0-0.3-0.9-0.10.6-1.3-1.3-1.4-0.8-0.81.00.91.7
Lifetime Intake0.60.71.60.2-0.3-0.20.8-1.2-1.1-1.2-0.90.21.00.90.9
Liver weight, left0.91.64.4-0.52.10.4-0.91.71.81.71.0-0.4-0.9-0.8-1.3
Liver weight, right0.40.72.8-0.31.7-0.20.01.21.31.3-0.1-0.5-0.3-0.2-0.9
Locomotor activity0.71.16.1-1.41.80.20.00.70.70.70.0-2.50.30.40.9
Locomotor testing distance0.20.51.9-0.71.40.4-0.30.80.80.80.5-1.3-0.2-0.2-0.0
Locomotor testing rearing0.31.32.4-0.81.51.0-1.01.31.31.61.1-0.3-1.1-1.0-1.0
Locomotion in novel chamber0.10.10.3-0.3-0.30.6-0.30.30.20.20.2-0.1-0.2-0.30.0
Locomotion in novel chamber post-restriction0.51.52.8-1.31.11.4-1.21.71.61.41.2-0.2-1.2-1.2-0.6
Fecal boli incidents, locomotor time 10.20.52.71.0-1.0-0.3-0.3-0.5-0.5-0.3-0.21.6-0.2-0.2-0.7
Change in fecal boli incidents, locomotor task0.80.82.8-0.91.70.2-0.31.31.21.30.5-1.0-0.4-0.3-0.4
Time >=10cm from walls, locomotor time 13.64.58.7-0.92.31.5-1.73.02.92.71.80.4-2.2-2.2-2.2
Bouts of movement, locomotor time 10.20.20.30.6-0.6-0.50.5-0.5-0.6-0.4-0.5-0.30.60.50.4
Total resting periods, locomotor time 10.20.20.40.6-0.5-0.70.6-0.4-0.5-0.3-0.6-0.20.60.50.4
Rest time, locomotor task time 10.20.30.80.5-0.4-0.90.7-0.2-0.3-0.4-0.8-0.20.80.70.4
Distance moved, locomotor task time 10.30.71.2-1.11.10.9-0.90.70.90.81.1-0.4-0.9-0.8-0.3
Vertical activity count, locomotor time 10.32.03.6-1.71.61.9-1.51.31.41.21.7-0.1-1.5-1.5-0.7
Time >=10cm from walls, locomotor time 20.71.94.8-1.42.20.9-1.21.81.81.80.9-0.4-1.0-1.0-1.0
Bouts of movement, locomotor time 20.20.62.4-0.50.4-0.10.7-0.3-0.3-0.2-0.7-1.50.80.81.2
Total resting periods, locomotor time 20.31.13.2-0.20.1-0.71.2-0.6-0.6-0.5-1.3-1.81.31.41.5
Rest time, locomotor task time 20.30.51.51.2-0.3-0.70.30.60.50.6-0.20.9-0.4-0.3-1.2
Distance moved, locomotor task time 20.81.02.3-1.30.71.5-1.40.60.70.71.40.3-1.0-1.0-0.4
Vertical activity count, locomotor time 20.41.02.1-1.31.01.4-1.10.80.90.71.30.2-0.9-1.0-0.4
Light reinforcement 10.83.76.0-0.71.32.0-2.31.91.92.12.50.8-2.3-2.3-2.1
Light reinforcement 20.92.13.9-0.20.91.4-1.61.51.51.31.61.2-1.6-1.8-2.0
Bone: marrow area0.92.36.9-1.32.60.1-0.72.22.32.10.5-1.4-0.6-0.5-0.8
Bone: maximum diameter0.20.41.70.8-0.1-1.31.00.30.20.1-0.9-0.20.60.7-0.3
Bone: maximum force1.02.12.9-1.31.21.7-1.71.61.61.71.50.1-1.5-1.5-1.0
Bone: maximum moment0.61.11.6-1.10.91.3-1.31.21.21.31.10.1-1.1-1.1-0.7
Mean time between licks in bursts0.31.54.41.7-0.4-2.11.7-0.9-0.9-0.6-1.7-0.21.31.40.1
Mean num. licks in bursts0.10.41.3-1.1-0.21.1-0.6-0.3-0.3-0.40.3-0.3-0.2-0.21.0
Cd content in liver1.51.76.50.6-0.31.1-1.20.40.40.51.52.6-1.4-1.4-1.8
Co content in liver2.02.33.9-1.31.31.8-1.81.51.51.52.00.6-1.7-1.7-1.1
Cu content in liver0.40.51.30.1-0.80.10.4-1.2-1.2-1.0-0.2-0.10.50.41.0
Fe content in liver0.60.71.6-0.70.21.3-1.10.80.80.81.10.4-1.0-1.0-0.5
K content in liver0.60.61.91.3-1.4-0.60.8-0.7-0.7-0.5-0.40.90.30.3-0.2
Mg content in liver0.80.93.41.9-0.9-1.31.5-0.6-0.6-0.5-0.70.70.50.6-0.6
Mn content in liver0.60.62.31.5-0.3-0.90.70.40.40.5-0.31.1-0.2-0.0-1.4
Na content in liver0.20.20.9-0.3-0.3-0.00.4-0.4-0.4-0.2-0.3-1.00.40.40.9
Rb content in liver0.40.42.31.0-0.6-0.00.10.00.0-0.10.41.5-0.4-0.4-1.1
Se content in liver1.61.94.81.0-0.2-2.22.0-0.9-0.9-0.9-1.7-1.11.71.80.8
Sr content in liver0.10.10.40.10.10.0-0.30.30.30.40.30.6-0.2-0.2-0.6
Zn content in liver0.20.20.70.50.1-0.2-0.00.00.00.30.30.8-0.3-0.2-0.8
Bone: minimum diameter0.30.51.50.10.7-0.50.11.21.21.10.1-0.1-0.3-0.3-1.0
Time in familiar zone, hab. session 11.51.73.90.6-2.0-0.30.7-1.9-1.9-1.8-0.90.21.01.01.5
Time in novel zone, hab. session 11.21.33.7-0.91.90.3-0.71.61.61.60.7-0.7-0.8-0.8-0.9
Total zone transitions, hab. session 10.20.31.11.0-0.9-0.60.7-0.6-0.6-0.4-0.40.30.30.4-0.0
Total locomotion distance, hab. session 10.30.51.71.3-1.2-0.40.7-0.5-0.5-0.4-0.30.80.20.1-0.4
Locomotion velocity, hab. session 10.20.30.90.9-0.9-0.40.7-0.4-0.5-0.4-0.40.30.30.3-0.1
Time in familiar zone, hab. session 20.20.20.7-0.60.30.8-0.50.10.10.20.5-0.7-0.4-0.30.3
Time in novel zone, hab. session 20.10.10.2-0.30.5-0.40.1-0.1-0.1-0.1-0.30.00.40.30.2
Total zone transitions, hab. session 20.40.61.30.6-0.60.7-0.40.60.60.60.80.9-0.9-0.9-1.1
Total locomotion distance, hab. session 20.71.03.11.6-1.40.30.10.10.0-0.00.51.8-0.7-0.8-1.4
Locomotion velocity, hab. session 20.81.13.92.0-1.7-0.00.5-0.2-0.2-0.30.11.8-0.4-0.5-1.3
Novel to familiar place preference ratio0.30.40.70.2-0.1-0.70.5-0.7-0.7-0.8-0.8-0.20.80.70.6
Novelty place preference0.40.50.9-0.00.2-0.80.6-0.7-0.7-0.7-0.9-0.50.90.90.9
Time in novel zone, NPP test0.50.61.0-0.20.3-0.80.6-0.6-0.6-0.7-1.0-0.81.01.01.0
Total zone transitions, NPP test0.91.44.62.1-1.9-0.71.0-1.0-1.0-0.9-0.61.80.20.3-0.7
Total locomotion distance, NPP test1.21.77.82.2-1.9-0.10.5-0.5-0.6-0.60.12.8-0.4-0.5-1.5
Locomotion velocity, NPP test1.62.39.92.6-2.4-0.20.6-0.6-0.7-0.80.03.1-0.5-0.5-1.7
Intraocular pressure0.10.20.70.3-0.50.7-0.6-0.2-0.2-0.20.50.8-0.3-0.3-0.1
Delta distance traveled before/after self-admin1.41.56.8-1.91.5-0.30.3-0.1-0.00.1-0.7-2.60.90.91.8
Delta ambulatory time before/after self-admin0.81.46.4-1.81.6-0.60.30.10.20.3-0.6-2.50.80.81.6
Parametrial fat weight2.86.610.4-1.41.13.0-3.12.93.02.13.21.4-3.0-3.2-2.3
Pavlov. Cond. lever latency5.46.912.1-2.92.53.5-3.42.32.32.73.1-0.5-2.7-2.7-1.0
Pavlov. Cond. magazine entry latency3.74.87.61.3-1.4-2.72.8-1.9-2.0-2.2-2.7-1.22.62.61.9
Pavlov. Cond. change in total contacts2.02.13.70.6-0.5-1.91.9-1.1-1.2-1.4-1.9-1.01.81.81.3
Pavlov. Cond. index score4.65.810.32.3-2.3-3.23.2-2.0-2.1-2.4-2.9-0.22.72.61.2
Pavlov. Cond. latency score4.86.111.12.4-2.3-3.33.3-2.0-2.1-2.5-3.0-0.22.72.71.3
Pavlov. Cond. lever contacts3.44.17.92.8-2.2-2.82.7-1.5-1.5-2.0-2.31.01.91.80.1
Pavlov. Cond. magazine entry number2.73.45.4-1.21.32.3-2.31.61.71.92.30.9-2.2-2.2-1.5
Pavlov. Cond. intertrial magazine entries0.81.02.2-0.30.41.5-1.40.20.20.21.31.4-1.2-1.2-0.8
Pavlov. Cond. lever-magazine prob. diff.4.65.810.02.3-2.4-3.13.2-2.0-2.1-2.5-2.9-0.12.72.61.2
Pavlov. Cond. response bias3.13.96.81.9-1.6-2.62.6-1.7-1.7-2.1-2.4-0.22.22.21.0
Pavlov. Cond. lever latency0.71.02.10.11.00.4-0.61.31.31.30.70.6-1.1-0.9-1.4
Pavlov. Cond. magazine entry latency0.40.60.90.7-0.7-0.90.8-0.8-0.8-0.9-0.80.20.90.80.4
Pavlov. Cond. change in total contacts0.51.12.9-0.4-0.5-0.70.9-1.0-1.0-1.1-1.0-1.31.31.21.7
Pavlov. Cond. index score0.71.01.60.2-0.9-0.80.9-1.2-1.2-1.2-1.0-0.61.21.11.2
Pavlov. Cond. latency score0.50.81.4-0.0-0.8-0.60.8-1.0-1.0-1.0-0.8-0.61.11.01.2
Pavlov. Cond. lever contacts0.50.71.6-0.2-0.8-0.30.5-1.1-1.1-1.2-0.4-0.51.00.81.2
Pavlov. Cond. magazine entry number0.10.10.3-0.30.60.3-0.30.40.40.50.2-0.3-0.4-0.2-0.1
Pavlov. Cond. intertrial magazine entries0.20.51.20.70.1-1.11.0-0.5-0.5-0.4-1.1-0.70.70.80.4
Pavlov. Cond. lever-magazine prob. diff.0.50.81.20.1-0.9-0.70.8-1.0-1.0-1.1-0.8-0.51.11.01.1
Pavlov. Cond. response bias0.81.11.90.4-1.3-0.80.9-1.3-1.3-1.4-0.8-0.31.31.11.1
Time in closed arm before self-admin0.00.10.3-0.10.1-0.40.30.20.20.2-0.2-0.50.20.30.3
Time in closed arm after self-admin0.10.10.20.1-0.30.3-0.20.30.30.30.10.4-0.2-0.2-0.3
Time in open arm before self-admin1.51.92.90.6-0.6-1.31.3-1.7-1.6-1.6-1.6-0.71.71.61.4
Time in open arm after self-admin0.91.01.50.0-0.1-1.11.0-1.2-1.1-1.0-1.2-0.81.21.21.2
Bone: periosteal estimation0.61.43.4-1.31.80.3-0.61.71.81.70.4-1.4-0.4-0.4-0.4
Bone: periosteal perimeter0.20.30.8-0.30.8-0.50.30.80.80.6-0.2-0.90.10.2-0.1
Bone: post-yield work0.20.41.60.70.1-0.40.00.70.70.60.10.8-0.4-0.3-1.3
Progressive ratio test 1 active lever presses0.10.20.50.4-0.50.20.3-0.7-0.5-0.7-0.50.60.40.50.2
Progressive ratio test 1 breakpoint0.10.20.50.4-0.40.10.3-0.7-0.5-0.7-0.50.50.40.50.2
Progressive ratio test 1 inactive lever presses0.20.61.50.2-0.21.2-0.80.20.30.21.01.2-1.0-0.9-0.9
Progressive ratio test 2 active lever presses0.30.41.00.7-0.8-0.20.5-1.0-0.9-0.9-0.50.60.60.50.3
Progressive ratio test 2 breakpoint0.40.61.30.7-0.8-0.20.6-1.1-1.1-1.0-0.60.50.70.60.5
Progressive ratio test 2 inactive lever presses0.20.71.31.1-0.7-0.80.9-1.0-0.9-0.7-0.90.90.80.7-0.1
Incentive Sensitization - Responses0.20.61.00.7-0.5-0.80.8-1.0-1.0-0.8-0.7-0.10.80.70.6
Incentive Sensitization - Breakpoint0.20.50.90.8-0.6-0.70.7-1.0-0.9-0.8-0.50.10.60.60.4
Sum of active levers in priming session hrs 5-60.80.71.30.4-0.2-1.20.9-0.9-0.9-0.8-1.1-0.41.11.00.7
Progressive ratio1.95.610.5-3.22.92.6-2.52.52.42.62.4-1.8-2.0-1.9-0.2
Food seeking constrained by brief footshock0.20.30.7-0.4-0.40.10.1-0.7-0.7-0.6-0.4-0.30.60.40.8
Seeking ratio, punishment vs. effort2.14.66.22.2-2.2-2.32.2-2.5-2.4-2.5-2.50.72.22.10.9
Retroperitoneal fat weight0.41.62.90.10.01.3-1.21.21.30.61.71.6-1.6-1.6-1.6
Reaction time number correct0.31.12.4-1.41.11.4-1.50.60.61.11.1-0.4-1.0-0.90.0
Reaction time mean minus median0.32.04.71.9-1.3-2.22.0-1.1-1.0-1.4-1.40.61.31.30.1
Reaction time mean minus median AUC0.43.05.92.3-1.7-2.42.2-1.5-1.5-1.9-1.71.31.51.50.1
Reaction time num false alarms0.10.20.90.10.3-0.40.6-0.2-0.2-0.1-0.5-0.90.50.50.3
Reaction time num false alarms AUC0.20.52.6-0.30.8-0.40.7-0.1-0.10.0-0.6-1.60.70.60.6
Reaction time trials correct on left0.31.12.4-1.41.11.4-1.50.60.61.11.1-0.4-1.0-0.90.0
Reaction time trials on left0.31.02.2-1.31.11.3-1.50.60.61.11.0-0.5-1.0-0.90.0
Reaction time mean0.71.54.62.1-1.5-1.81.3-0.3-0.3-0.8-0.81.80.50.5-1.1
Reaction time mean AUC0.61.54.32.1-1.5-1.71.3-0.4-0.3-0.9-0.91.80.50.5-1.0
Median of all reaction times0.61.03.61.7-1.2-1.20.80.10.1-0.4-0.41.90.00.0-1.3
Reaction time omissions0.50.82.91.7-1.0-1.11.2-0.4-0.4-0.6-0.61.10.40.3-0.8
Reaction time false alarm rate0.81.12.70.5-0.0-1.41.6-0.6-0.5-0.7-1.3-1.31.31.30.7
Reaction time premature initiation rate0.10.20.4-0.3-0.00.2-0.60.50.50.50.40.3-0.4-0.5-0.5
Reaction time premature initiations0.41.12.5-1.20.81.1-1.61.01.01.21.0-0.1-1.0-1.1-0.4
Std. dev. reaction times0.72.36.11.8-1.2-2.52.2-1.0-1.0-1.4-1.80.31.61.60.3
Reaction time trials completed0.31.02.2-1.31.11.3-1.50.60.61.11.0-0.5-1.0-0.90.0
Reaction time trials AUC0.31.12.5-1.31.11.4-1.60.70.71.21.2-0.3-1.1-1.0-0.2
Run reversals in cocaine runway, females0.20.31.1-0.1-0.61.0-0.5-0.2-0.0-0.20.60.7-0.3-0.4-0.2
Run reversals in cocaine runway, males0.50.61.01.0-0.8-0.70.9-0.7-0.8-0.7-1.00.20.80.80.1
Latency to leave start box in cocaine runway0.40.51.71.3-0.7-1.10.5-0.10.10.0-0.41.20.00.0-0.9
Latency to leave start box in cocaine runway, F0.30.41.61.3-0.6-0.80.5-0.3-0.2-0.3-0.41.20.20.2-0.7
Latency to leave start box in cocaine runway, M0.20.20.60.2-0.4-0.3-0.10.60.80.70.00.4-0.5-0.4-0.7
Std. dev. time between licks in bursts0.50.93.21.1-0.3-1.81.6-0.1-0.10.1-1.2-0.61.01.0-0.1
Total sessions with >9 infusions0.60.81.6-0.30.30.10.7-1.0-0.9-1.3-1.1-0.61.11.11.2
Short access day 1 total inactive lever presses0.30.51.20.8-0.1-0.90.9-0.5-0.5-0.8-1.10.50.90.80.1
Short access day 10 total inactive lever presses0.10.41.40.80.40.2-0.20.20.10.60.70.6-0.8-0.7-1.2
Short access day 1 total infusions0.51.12.10.5-0.1-0.91.1-1.3-1.2-1.4-1.40.21.21.20.8
Short access day 10 total infusions0.30.51.70.4-0.30.30.5-1.1-1.0-1.3-0.50.50.60.60.5
Short access total infusions0.50.82.20.4-0.2-0.20.9-1.1-1.1-1.5-1.00.41.00.90.7
Short access day 1 locomotion0.30.41.31.1-0.5-0.30.8-0.6-0.6-1.0-0.70.70.40.5-0.2
Short access day 10 total locomotion0.41.65.3-1.42.31.3-0.71.41.51.50.3-1.7-0.4-0.4-0.2
Short access total locomotion0.10.21.1-0.21.10.5-0.10.50.60.3-0.0-0.1-0.2-0.1-0.4
One hour access (0.3 mA shock)0.70.92.21.5-1.4-0.41.0-1.2-1.1-1.0-0.70.70.70.60.1
Compulsive drug intake0.71.13.71.8-0.7-0.30.41.00.80.90.41.2-0.8-0.8-1.9
One hour access (shock baseline)0.30.81.9-0.1-0.6-0.20.5-1.4-1.3-1.3-0.6-0.01.10.91.3
Social response proportion0.40.51.3-0.71.10.4-0.31.01.01.00.2-0.5-0.5-0.4-0.4
Social responses0.50.61.9-1.01.40.4-0.20.81.01.00.2-1.3-0.3-0.10.1
Social time0.30.41.61.30.3-0.70.90.40.50.4-0.30.0-0.20.0-1.0
Soleus weight0.31.02.70.61.4-0.90.21.41.41.3-0.00.0-0.3-0.2-1.6
Bone: stiffness1.01.83.0-0.90.91.7-1.61.21.21.51.50.3-1.6-1.6-1.1
Tibialis anterior weight0.20.62.3-0.70.51.5-0.90.40.40.60.90.0-0.8-0.8-0.1
Time to tail flick, vehicle, before self-admin0.70.81.60.4-0.10.9-0.61.01.00.91.20.5-1.3-1.1-1.1
Time to tail flick, vehicle, after self-admin0.20.40.70.6-0.3-0.80.8-0.6-0.6-0.5-0.8-0.10.70.70.3
Time to tail flick, test, before self-admin0.20.21.1-0.30.10.20.3-0.2-0.2-0.40.2-1.10.30.30.9
Time to tail flick, test, after self-admin2.42.54.51.4-1.8-1.41.5-2.1-2.0-1.9-1.50.01.51.51.2
Delta time to tail flick, vehicle, before/after SA2.02.13.80.8-1.3-1.31.2-1.9-1.9-1.9-1.60.41.71.51.2
Delta time to tail flick, test, before/after SA0.50.62.31.1-1.4-0.30.1-0.7-0.6-0.4-0.21.5-0.1-0.2-0.6
Tibia length0.92.65.9-1.32.40.6-1.02.42.42.20.8-1.3-1.1-1.0-1.0
Ambulatory time before self-admin0.10.30.70.5-0.10.5-0.30.40.40.40.50.7-0.6-0.6-0.8
Ambulatory time after self-admin0.50.82.4-1.21.50.3-0.41.11.11.10.3-1.4-0.4-0.30.1
Bone: tissue strength0.20.20.6-0.20.20.4-0.50.20.30.30.60.8-0.4-0.5-0.6
Total heroin consumption0.00.00.20.10.3-0.20.20.20.20.2-0.1-0.40.00.1-0.0
Bone: trabecular number1.01.95.92.0-2.4-0.30.7-1.6-1.7-1.6-0.32.00.20.2-0.3
Bone: trabecular spacing1.42.05.8-2.12.40.5-1.01.81.91.20.3-1.9-0.3-0.30.3
Bone: trabecular thickness0.71.04.11.4-2.00.30.2-0.8-0.8-0.50.22.0-0.4-0.4-0.7
Bone: trabecular tissue density0.81.33.2-0.50.3-1.10.8-0.7-0.7-0.8-1.3-1.81.51.51.8
Water consumed over 24 hours0.00.00.10.10.1-0.30.20.30.30.2-0.2-0.10.00.0-0.2
Number of responses in last shaping day0.71.02.5-0.40.5-1.51.0-0.1-0.1-0.1-1.6-1.41.21.10.8