Hub : Genes

Taco1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Taco1 0.09 0.04 2.0e-10 0.09 0.09 0.09 0.1 1.8e-10 2.0e-10 4.1e-10 1.4e-10
2 Adipose gene expression Taco1 0.05 0.03 2.8e-05 0.04 0.04 0.03 0.04 2.3e-05 3.9e-05 8.0e-04 6.3e-05
3 Liver mRNA stability Taco1 0.09 0.04 5.1e-14 0.1 0.11 0.1 0.1 3.0e-11 6.0e-12 1.1e-11 1.1e-11
4 LHb mRNA stability Taco1 0.17 0.09 1.6e-03 0.15 0.09 0.05 0.09 1.9e-04 4.4e-03 3.0e-02 4.5e-03
5 Brain mRNA stability Taco1 0.14 0.06 0.0e+00 0.18 0.17 0.17 0.18 1.0e-16 1.1e-15 3.3e-15 1.0e-16
6 pVTA mRNA stability Taco1 0.07 0.04 3.0e-03 0.1 0.05 0.09 -0 5.7e-05 2.4e-03 1.2e-04 4.8e-01
7 BLA mRNA stability Taco1 0.1 0.05 6.5e-07 0.12 0.1 0.11 0.12 4.0e-07 3.0e-06 1.2e-06 6.4e-07
8 Liver gene expression Taco1 0.12 0.05 8.2e-14 0.11 0.1 0.1 0.1 4.1e-12 7.6e-11 3.4e-11 4.0e-11
9 Adipose mRNA stability Taco1 0.08 0.04 6.5e-08 0.06 0.06 0.06 0.06 5.4e-07 1.1e-07 2.3e-07 8.1e-07
10 NAcc mRNA stability Taco1 0.2 0.11 6.4e-12 0.1 0.1 0.12 0.11 8.9e-12 7.9e-12 2.4e-13 1.1e-12
11 RMTg gene expression Taco1 0.21 0.12 4.4e-03 0.04 0.06 0.08 0.06 4.1e-02 9.6e-03 3.5e-03 1.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density2.84.77.5-2.52.1-2.12.4-2.51.91.62.7-2.11.91.7
Area under the delay curve0.10.10.3-0.20.1-0.50.1-0.20.2-0.10.50.10.30.4
BMI with tail0.20.51.11.1-0.20.2-1.00.6-0.2-0.7-0.60.9-0.7-0.8
BMI without tail0.61.21.9-0.81.2-1.40.6-1.21.01.21.4-0.91.0-1.1
Body weight1.35.69.5-2.13.1-3.02.1-2.33.12.42.0-1.82.0-1.7
Weight adjusted by age1.01.21.81.3-1.30.8-1.11.0-1.2-1.0-1.01.3-0.2-1.1
Bone surface8.515.019.5-4.44.1-4.14.4-4.34.03.84.2-3.73.6-0.3
Bone volume6.911.715.6-3.83.6-3.73.9-3.83.43.04.0-3.33.30.1
Breakpoint value in progressive ratio session1.11.22.1-1.20.8-1.01.1-1.10.71.10.7-1.11.4-1.4
Number of licking bursts0.10.10.4-0.10.0-0.20.3-0.0-0.0-0.2-0.10.20.3-0.6
Context. condit. distance diff. score0.50.71.30.9-0.50.7-1.10.7-0.3-0.6-1.10.8-1.0-0.8
Locomotion velocity, session 12.02.13.1-1.81.7-1.31.4-1.51.61.61.6-1.50.90.9
Locomotion distance, session 10.30.42.1-0.70.4-0.40.2-0.30.61.00.6-0.40.11.4
Locomotion velocity, session 21.01.22.1-1.30.9-0.81.5-1.01.01.20.8-1.41.2-0.5
Locomotion distance, session 20.10.10.6-0.40.4-0.10.10.10.60.8-0.1-0.2-0.10.5
Locomotion velocity, session 30.10.10.30.2-0.50.4-0.00.2-0.4-0.3-0.30.4-0.10.6
Locomotion distance, session 30.10.10.4-0.40.1-0.30.6-0.30.30.40.2-0.10.4-0.1
Stereotopy head waving bouts, day 30.30.32.70.1-0.40.4-0.30.1-0.5-0.50.30.3-0.11.6
Stereotopy head waving duration, day 30.30.40.70.6-0.60.5-0.80.4-0.6-0.7-0.20.7-0.40.8
Locomotion velocity, session 70.40.51.80.4-0.40.7-0.50.5-0.3-0.4-0.60.4-1.11.3
Locomotion distance, session 70.10.10.30.3-0.50.2-0.50.2-0.3-0.1-0.30.2-0.3-0.1
Stereotopy head waving bouts, day 70.20.21.10.1-0.30.5-0.10.3-0.3-0.5-0.00.2-0.31.0
Stereotopy head waving duration, day 71.01.21.80.9-1.01.3-0.81.2-0.9-1.3-1.11.0-1.11.3
Locomotion velocity, session 80.40.51.5-0.41.1-0.60.5-0.21.20.5-0.4-0.4-0.1-1.1
Locomotion distance, session 80.10.10.40.3-0.10.2-0.50.40.3-0.0-0.70.2-0.3-0.4
Degree of sensitization distance0.10.10.50.30.1-0.1-0.70.20.10.1-0.10.0-0.4-0.3
Degree of sensitization stereotypy0.50.61.00.5-0.61.0-0.51.0-0.5-0.8-0.80.6-0.90.8
Conditioned locomotion0.20.30.9-0.30.2-0.60.4-0.40.30.40.5-0.71.0-0.7
Cocaine response after cond. corrected0.20.20.70.6-0.50.1-0.10.3-0.4-0.3-0.50.8-0.2-0.2
Cocaine response after cond. not corrected0.10.10.40.3-0.40.10.30.1-0.2-0.2-0.50.6-0.1-0.0
Cocaine response before conditioning0.10.10.3-0.50.20.00.5-0.40.2-0.00.2-0.30.30.6
Saline control response0.81.03.0-0.80.8-0.90.6-0.90.81.00.8-1.31.1-1.7
Bone: connectivity density3.75.88.0-2.82.4-2.42.6-2.72.32.22.8-2.52.11.2
Bone: cortical apparent density4.96.59.42.5-2.72.6-2.62.5-2.7-2.4-1.92.3-2.53.1
Bone: cortical area2.74.06.6-2.11.7-2.22.4-2.31.81.62.6-1.72.4-0.0
Bone: cortical porosity13.314.522.1-4.13.5-3.64.7-4.33.53.83.3-3.74.0-2.9
Bone: cortical porosity8.08.713.5-3.12.8-2.93.7-3.32.82.92.6-2.73.1-2.3
Bone: cortical thickness2.23.711.81.5-2.21.8-1.21.4-2.2-2.1-0.71.9-1.33.4
Bone: cortical thickness2.12.56.61.2-1.91.7-1.01.1-1.8-1.6-0.91.2-1.52.6
Bone: cortical tissue density4.86.39.02.4-2.62.6-2.62.5-2.7-2.4-1.92.2-2.53.0
Condit. Reinf. active minus inactive responses3.23.64.5-2.11.7-1.91.8-2.11.81.91.9-2.12.0-1.5
Condit. Reinf. active-inactive response ratio1.31.42.0-1.31.2-1.11.0-1.41.31.01.3-1.41.0-1.0
Condit. Reinf. active responses3.74.55.7-2.22.0-2.22.2-2.22.02.22.0-2.32.4-1.5
Condit. Reinf. inactive responses1.21.42.2-1.11.2-1.41.3-1.01.11.41.0-1.11.5-0.2
Incentive salience index mean3.74.56.1-2.52.1-2.02.3-2.22.12.32.0-2.32.1-0.9
Condit. Reinf. lever presses0.91.22.4-1.41.2-0.81.5-0.91.11.30.8-1.31.00.2
Condit. Reinf. active minus inactive responses7.99.712.2-3.43.0-3.43.3-3.53.23.43.0-3.13.1-1.5
Condit. Reinf. active-inactive response ratio5.86.18.2-2.72.4-2.62.8-2.92.42.52.4-2.62.3-0.9
Condit. Reinf. active responses7.410.212.4-3.42.9-3.43.2-3.53.13.53.0-3.33.5-2.0
Condit. Reinf. inactive responses1.41.83.4-1.20.9-1.41.1-1.21.21.51.3-1.51.8-1.2
Condit. Reinf. lever presses2.23.04.7-1.91.6-1.71.9-1.91.62.21.4-1.91.7-0.9
Condit. Reinf. lever reinforcers received6.59.111.4-3.22.6-3.23.1-3.42.83.32.9-3.13.4-1.8
Conditioned reinforcement - actives0.50.51.0-0.81.0-0.80.5-0.70.80.90.8-0.60.4-0.4
Conditioned reinforcement - inactives1.11.22.2-1.21.5-1.21.2-1.11.41.01.2-1.10.6-0.0
Conditioned locomotion2.63.14.1-1.92.0-1.91.7-1.91.91.92.0-1.81.3-0.0
Patch foraging indifference point 0 sec3.55.67.6-2.42.5-2.72.0-2.52.62.12.8-2.62.4-0.5
Patch foraging indifference point AUC0.60.71.2-0.91.0-1.00.7-0.61.10.90.6-0.70.9-0.7
Delay disc. indifference point, 0s delay0.60.71.31.0-1.20.7-0.80.8-1.1-0.9-0.61.0-0.20.6
Delay disc. indifference point, 16s delay0.30.31.2-0.50.1-0.80.5-0.60.20.10.9-0.21.1-0.4
Delay disc. indifference point, 2s delay0.50.61.3-0.70.7-1.10.5-0.70.80.41.0-0.40.41.1
Delay disc. indifference point, 24s delay1.31.22.2-1.21.1-1.50.9-1.01.20.91.4-0.91.3-0.2
Delay disc. indifference point, 4s delay0.30.30.60.5-0.80.5-0.40.5-0.7-0.7-0.40.8-0.40.5
Delay disc. indifference point, 8s delay0.20.21.70.2-0.40.1-0.30.1-0.3-0.50.20.3-0.11.3
Indifference point function ln k0.10.20.60.1-0.60.10.3-0.3-0.6-0.30.40.10.50.8
Indifference point function log k0.10.20.60.1-0.60.10.3-0.3-0.6-0.30.40.10.50.8
Patch foraging total patch changes 0 sec3.86.28.2-2.62.6-2.92.2-2.62.72.22.8-2.72.6-0.7
Patch foraging total patch changes 12 sec3.54.56.9-2.22.6-2.41.6-1.92.62.02.1-2.32.0-1.3
Patch foraging total patch changes 18 sec2.43.03.5-1.71.8-1.91.5-1.71.81.81.5-1.81.8-1.9
Patch foraging total patch changes 24 sec3.64.55.9-2.32.2-2.41.9-2.32.31.92.3-2.22.1-0.5
Patch foraging total patch changes 6 sec2.33.55.0-2.01.9-2.01.7-2.02.01.62.2-1.82.0-0.8
Patch foraging time to switch 0 sec0.10.10.30.3-0.30.60.00.3-0.4-0.4-0.50.1-0.3-0.2
Patch foraging water rate 0 sec1.32.13.2-1.51.6-1.71.2-1.61.71.41.8-1.51.00.5
Patch foraging water rate 12 sec0.60.91.60.8-1.00.8-0.80.6-0.9-1.1-0.31.2-1.01.3
Patch foraging water rate 18 sec0.30.32.5-0.50.2-0.30.3-0.40.40.00.6-0.1-0.21.6
Patch foraging water rate 24 sec0.10.10.30.00.3-0.10.10.10.30.1-0.20.2-0.50.5
Patch foraging water rate 6 sec0.30.42.6-0.40.0-0.30.3-0.7-0.0-0.00.9-0.10.11.6
Seeking ratio, delayed vs. immediate footshock0.00.10.20.20.20.2-0.40.30.20.2-0.2-0.0-0.40.0
Distance traveled before self-admin0.60.64.30.4-0.70.10.30.2-0.7-0.1-0.50.90.5-2.1
Distance traveled after self-admin0.60.65.90.2-0.30.0-0.00.1-0.30.1-0.40.60.5-2.4
Extensor digitorum longus weight2.59.815.23.9-3.13.0-3.63.5-3.2-3.2-3.33.0-2.8-0.6
Bone: elastic displacement1.01.12.80.7-0.81.1-0.80.8-0.7-0.8-0.91.1-1.51.7
Bone: elastic work0.50.62.3-0.80.7-0.40.8-0.70.60.90.7-0.5-0.11.5
Bone: endosteal estimation16.135.140.5-6.16.2-6.26.0-6.26.16.45.4-5.95.8-4.6
Bone: endosteal perimeter17.736.843.4-6.16.4-6.66.0-6.26.46.15.7-5.66.2-5.2
Epididymis fat weight0.51.12.2-0.81.2-1.30.8-1.21.10.81.5-1.10.9-0.3
Delta time in closed arm before/after self-admin0.20.20.6-0.40.6-0.20.3-0.20.80.6-0.1-0.2-0.20.5
Delta time in open arm before/after self-admin0.90.82.01.1-1.20.8-0.90.9-1.4-1.1-0.60.7-0.3-0.1
Diff in mean of infusions in LGA sessions1.01.11.41.2-1.01.2-1.01.1-1.2-1.0-1.21.0-1.10.2
Delay discount exponential model param0.20.20.50.4-0.40.7-0.30.4-0.5-0.1-0.70.2-0.4-0.3
Extinction: sum of active levers before priming0.20.21.3-0.2-0.1-0.40.0-0.2-0.20.30.0-0.20.6-1.2
Active lever presses in extinction session 62.92.84.8-1.71.4-1.62.0-1.81.11.61.7-1.72.2-1.6
Bone: final force1.42.33.6-1.81.4-1.61.6-1.71.41.51.9-1.01.60.5
Bone: final moment1.62.64.0-1.91.5-1.71.8-1.81.51.72.0-1.21.70.6
Food consumed during 24 hour testing period2.12.54.2-1.52.1-1.81.4-1.32.01.81.2-1.61.0-1.4
Glucose1.11.62.71.4-1.51.1-0.91.2-1.4-1.3-1.61.5-0.9-0.7
Heart weight0.10.20.70.5-0.3-0.1-0.20.2-0.3-0.4-0.30.60.0-0.8
Delay discount hyperbolic model param0.10.10.40.3-0.20.6-0.20.3-0.40.1-0.60.1-0.2-0.5
Intermittent access intake day 1-15 change0.40.42.3-0.50.5-0.30.7-0.40.50.60.1-0.50.6-1.5
Intermittent access intake escalation0.10.10.5-0.20.20.10.30.00.20.4-0.2-0.2-0.0-0.7
Intermittent access intake escalation 20.60.60.9-0.80.9-0.60.8-0.60.80.90.5-0.80.5-0.8
Intermitt. access day 1 inactive lever presses6.06.58.6-2.72.4-2.72.9-2.72.62.42.5-2.62.9-1.1
Intermitt. access day 15 inactive lever presses3.53.96.7-2.01.4-1.82.3-2.21.51.72.3-2.42.6-0.5
Intermitt. access escalation Index3.32.94.81.8-1.71.6-1.71.9-1.4-1.8-2.12.2-1.7-0.3
Intermittent access day 1 total infusions0.70.81.4-0.91.0-1.21.0-0.90.80.81.2-0.60.7-0.0
Intermittent access day 15 total infusions0.30.40.7-0.60.8-0.70.6-0.50.70.80.6-0.40.3-0.6
Intermittent access terminal intake (last 3 days)2.12.33.1-1.61.8-1.71.5-1.51.61.71.6-1.51.3-0.9
Intermittent access total infusions2.62.94.3-1.82.1-1.91.7-1.71.92.01.8-1.61.2-0.6
Intermittent access day 1 locomotion3.94.15.8-2.22.4-2.32.0-2.22.12.22.4-1.81.2-0.2
Intermittent access day 15 total locomotion5.05.49.4-2.53.1-2.52.2-2.32.92.72.3-2.31.1-0.1
Intermittent access total locomotion8.09.113.6-3.33.7-3.22.9-3.13.43.43.3-3.11.8-0.1
Intermittent access standard deviation1.61.72.5-1.51.5-1.21.5-1.31.21.61.4-1.60.80.1
Left kidney weight0.41.02.20.9-1.00.8-0.90.9-0.8-0.8-0.81.4-1.11.5
Right kidney weight0.20.53.60.10.10.2-0.20.30.20.0-0.30.7-0.81.9
Cocaine induced anxiety0.10.10.4-0.0-0.30.00.0-0.3-0.4-0.40.50.00.10.6
Post-drug Anxiety0.10.10.50.2-0.60.2-0.1-0.1-0.7-0.40.30.30.10.4
Baseline Anxiety0.80.81.10.9-1.00.9-0.90.9-1.0-0.7-0.91.1-0.90.8
Tail length2.36.88.3-2.82.9-2.92.6-2.72.82.82.7-2.62.4-0.7
Length with tail2.38.311.9-3.13.4-3.33.1-2.83.53.12.5-2.52.6-0.7
Length without tail0.61.22.6-1.21.5-1.21.5-0.91.61.00.6-0.80.80.3
Times rat made contact with spout0.91.12.6-1.21.4-1.00.9-0.91.31.60.6-1.00.3-0.5
Lifetime Intake3.23.74.6-2.02.1-2.12.0-2.01.92.02.1-1.91.7-0.6
Liver weight, left0.81.22.6-1.21.4-1.41.2-1.11.61.10.6-1.00.9-0.2
Liver weight, right0.50.85.50.5-0.30.3-0.60.6-0.2-0.9-0.10.9-0.62.3
Locomotor activity0.50.92.0-1.11.4-0.80.7-0.71.41.30.5-1.0-0.0-0.4
Locomotor testing distance1.52.44.7-1.61.7-1.41.2-1.51.82.21.1-1.80.9-1.6
Locomotor testing rearing1.21.94.2-1.31.7-0.90.9-1.21.61.80.7-1.80.3-2.1
Locomotion in novel chamber0.10.20.5-0.10.6-0.1-0.20.00.70.4-0.30.4-0.70.1
Locomotion in novel chamber post-restriction1.62.03.5-1.41.3-1.91.4-1.61.21.11.7-1.01.6-0.7
Fecal boli incidents, locomotor time 10.30.42.60.1-0.6-0.1-0.10.2-0.4-0.3-0.20.40.9-1.6
Change in fecal boli incidents, locomotor task0.40.40.60.8-0.40.5-0.80.7-0.5-0.4-0.50.6-0.70.6
Time >=10cm from walls, locomotor time 12.52.54.11.9-1.51.6-1.51.7-1.3-1.8-2.01.9-1.4-0.3
Bouts of movement, locomotor time 10.50.61.60.6-0.70.8-0.80.5-0.8-1.0-0.20.3-0.91.3
Total resting periods, locomotor time 10.60.72.30.6-0.80.8-0.80.5-0.9-1.0-0.20.4-0.91.5
Rest time, locomotor task time 10.20.20.70.1-0.80.4-0.20.1-0.8-0.2-0.00.00.40.3
Distance moved, locomotor task time 10.60.72.0-0.71.4-0.70.6-0.61.30.90.7-0.7-0.40.5
Vertical activity count, locomotor time 10.60.61.4-0.71.2-0.70.8-0.61.10.80.7-0.6-0.10.5
Time >=10cm from walls, locomotor time 20.00.00.1-0.00.00.20.3-0.10.1-0.3-0.20.0-0.2-0.4
Bouts of movement, locomotor time 20.50.51.50.7-1.10.6-0.40.4-1.2-1.2-0.20.40.2-0.5
Total resting periods, locomotor time 20.90.92.21.0-1.40.9-0.80.7-1.5-1.5-0.50.7-0.1-0.5
Rest time, locomotor task time 24.35.09.22.4-3.02.1-2.32.0-3.0-2.6-1.82.4-0.9-0.0
Distance moved, locomotor task time 21.31.53.1-1.41.8-0.71.2-1.01.61.40.9-1.4-0.31.2
Vertical activity count, locomotor time 24.34.67.0-2.52.5-1.82.5-2.32.32.42.1-2.61.30.3
Light reinforcement 10.20.41.7-0.4-0.2-0.60.4-0.6-0.10.11.2-0.61.30.3
Light reinforcement 20.81.13.2-0.90.1-0.90.8-1.10.20.51.8-1.01.80.8
Bone: marrow area15.834.339.9-6.06.1-6.16.0-6.26.16.35.3-5.95.7-4.5
Bone: maximum diameter6.812.518.6-3.63.3-3.93.9-3.93.33.13.8-3.14.3-2.1
Bone: maximum force2.23.85.9-2.11.9-2.32.0-2.11.92.02.4-1.52.2-0.0
Bone: maximum moment2.44.26.5-2.22.0-2.32.2-2.22.02.12.5-1.62.20.1
Mean time between licks in bursts0.10.10.70.1-0.0-0.3-0.20.1-0.00.40.10.40.2-0.8
Mean num. licks in bursts0.20.30.9-0.50.6-0.40.1-0.40.61.00.5-0.6-0.10.3
Cd content in liver4.75.18.62.4-1.92.4-2.92.5-2.0-1.9-2.42.2-2.80.9
Co content in liver0.80.92.01.1-0.51.1-1.01.1-0.5-0.8-1.40.8-1.3-0.7
Cu content in liver0.40.41.1-0.60.1-0.50.9-0.80.20.30.9-0.91.10.1
Fe content in liver0.20.20.70.5-0.90.6-0.40.4-0.9-0.2-0.50.2-0.10.2
K content in liver1.21.12.4-1.11.0-1.31.5-0.91.10.50.9-0.91.6-0.5
Mg content in liver0.10.10.4-0.1-0.1-0.20.40.1-0.0-0.60.2-0.30.60.4
Mn content in liver0.40.42.1-0.70.3-0.50.8-0.20.40.10.7-0.40.71.4
Na content in liver0.50.61.7-0.70.2-0.81.0-0.70.40.10.5-0.61.3-1.1
Rb content in liver2.83.44.61.9-2.11.9-1.62.1-1.9-2.0-1.91.8-1.61.4
Se content in liver1.62.03.21.8-1.51.2-1.61.5-1.2-1.8-1.41.6-0.90.2
Sr content in liver0.60.60.8-0.80.9-0.80.8-0.90.90.80.8-0.50.5-0.0
Zn content in liver0.10.10.4-0.20.2-0.60.2-0.40.5-0.00.40.10.50.1
Bone: minimum diameter14.326.732.3-5.25.5-5.75.4-5.55.55.15.1-4.95.3-3.4
Time in familiar zone, hab. session 10.40.32.0-0.10.6-0.50.2-0.10.60.6-0.1-0.40.5-1.4
Time in novel zone, hab. session 10.70.71.60.6-1.10.9-0.50.4-1.1-1.0-0.20.7-0.81.3
Total zone transitions, hab. session 10.20.30.9-0.30.9-0.40.20.01.00.8-0.1-0.2-0.30.4
Total locomotion distance, hab. session 11.52.13.4-1.61.8-1.21.3-1.21.71.91.3-1.40.41.6
Locomotion velocity, hab. session 11.82.54.4-1.82.1-1.41.4-1.42.02.11.4-1.50.51.3
Time in familiar zone, hab. session 21.01.14.4-0.71.2-0.80.4-0.61.21.30.2-0.80.7-2.1
Time in novel zone, hab. session 21.11.16.00.5-1.20.7-0.30.5-1.2-1.20.00.7-0.62.5
Total zone transitions, hab. session 20.10.10.3-0.10.4-0.0-0.00.40.50.2-0.4-0.0-0.30.1
Total locomotion distance, hab. session 20.40.61.7-0.80.9-0.60.4-0.30.90.90.7-0.80.11.3
Locomotion velocity, hab. session 20.40.51.8-0.70.9-0.60.3-0.20.90.90.6-0.7-0.01.4
Novel to familiar place preference ratio0.30.30.7-0.60.4-0.70.6-0.80.50.10.8-0.40.7-0.4
Novelty place preference0.20.20.4-0.40.2-0.40.4-0.60.3-0.00.6-0.30.4-0.3
Time in novel zone, NPP test0.10.10.4-0.40.2-0.30.4-0.60.2-0.00.5-0.20.3-0.2
Total zone transitions, NPP test0.20.21.7-0.30.5-0.20.00.30.60.40.1-0.1-0.21.3
Total locomotion distance, NPP test1.11.53.5-1.31.5-0.90.9-0.81.51.41.1-1.20.11.9
Locomotion velocity, NPP test0.60.82.5-0.91.0-0.80.5-0.41.01.00.9-0.80.11.6
Intraocular pressure0.40.61.6-0.20.0-0.80.5-0.70.10.61.1-0.51.3-1.2
Delta distance traveled before/after self-admin0.20.20.60.3-0.30.6-0.80.4-0.4-0.5-0.30.3-0.50.2
Delta ambulatory time before/after self-admin0.10.10.3-0.20.20.0-0.4-0.00.20.10.1-0.2-0.10.5
Parametrial fat weight1.63.14.0-2.01.9-1.81.9-1.91.71.72.0-1.61.31.5
Pavlov. Cond. lever latency3.54.57.12.5-2.32.0-2.72.1-2.2-2.2-1.92.2-2.00.1
Pavlov. Cond. magazine entry latency5.16.69.6-2.92.6-2.63.1-2.52.52.42.6-2.72.8-0.6
Pavlov. Cond. change in total contacts4.54.88.0-2.42.2-2.02.8-2.22.02.12.0-2.52.4-0.5
Pavlov. Cond. index score4.65.89.0-2.72.5-2.43.0-2.42.42.32.3-2.52.6-0.7
Pavlov. Cond. latency score3.74.77.3-2.52.3-2.22.7-2.12.22.12.0-2.22.3-0.7
Pavlov. Cond. lever contacts2.93.45.9-2.12.0-1.72.4-1.81.91.91.6-2.01.7-0.5
Pavlov. Cond. magazine entry number4.15.17.52.6-2.12.2-2.72.3-2.0-2.0-2.42.5-2.60.2
Pavlov. Cond. intertrial magazine entries0.40.51.9-0.30.4-0.90.2-0.40.50.60.6-0.51.1-1.4
Pavlov. Cond. lever-magazine prob. diff.4.35.48.8-2.62.3-2.33.0-2.32.22.22.2-2.42.6-0.7
Pavlov. Cond. response bias6.07.311.5-3.12.6-2.63.4-2.82.52.62.8-2.93.0-0.1
Pavlov. Cond. lever latency0.40.60.80.8-0.70.8-0.80.9-0.7-0.7-0.60.7-0.70.8
Pavlov. Cond. magazine entry latency2.32.64.21.7-1.71.7-1.61.8-1.6-1.3-2.12.0-1.4-0.1
Pavlov. Cond. change in total contacts0.30.41.4-0.50.7-0.60.4-0.50.80.70.2-0.50.5-1.2
Pavlov. Cond. index score0.10.10.8-0.1-0.0-0.00.1-0.00.00.3-0.30.20.2-0.9
Pavlov. Cond. latency score0.10.10.7-0.0-0.10.10.1-0.0-0.10.3-0.30.30.1-0.9
Pavlov. Cond. lever contacts0.30.40.6-0.70.6-0.60.6-0.70.60.80.6-0.60.5-0.3
Pavlov. Cond. magazine entry number2.63.24.7-1.81.8-1.91.8-1.91.71.52.2-2.21.8-0.3
Pavlov. Cond. intertrial magazine entries12.316.019.7-4.13.8-4.44.2-4.23.93.84.3-4.44.4-2.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.70.1-0.10.1-0.00.1-0.10.1-0.40.40.1-0.8
Pavlov. Cond. response bias0.00.00.1-0.20.1-0.10.0-0.10.10.3-0.00.00.1-0.2
Time in closed arm before self-admin0.60.71.40.5-0.71.1-0.60.8-0.8-0.7-0.70.6-1.21.2
Time in closed arm after self-admin0.70.83.00.4-0.01.0-0.80.80.0-0.2-1.10.8-1.71.0
Time in open arm before self-admin0.30.40.80.6-0.50.5-0.60.4-0.2-0.8-0.70.9-0.8-0.3
Time in open arm after self-admin0.30.31.90.4-0.4-0.3-0.10.0-0.5-0.50.20.20.7-1.4
Bone: periosteal estimation12.225.229.9-5.35.0-5.45.4-5.55.05.15.1-4.95.3-2.7
Bone: periosteal perimeter7.412.214.8-3.73.5-3.83.8-3.83.63.33.6-2.93.8-2.4
Bone: post-yield work2.53.44.5-1.82.0-2.01.8-1.82.12.01.5-1.51.7-2.0
Progressive ratio test 1 active lever presses4.74.96.5-2.32.5-2.52.2-2.32.42.22.4-2.11.9-0.8
Progressive ratio test 1 breakpoint5.96.28.0-2.52.7-2.82.5-2.62.52.42.7-2.42.4-1.3
Progressive ratio test 1 inactive lever presses4.85.26.7-2.32.3-2.62.4-2.42.32.22.4-2.22.5-1.5
Progressive ratio test 2 active lever presses5.45.87.7-2.62.6-2.72.3-2.62.52.52.8-2.42.1-0.5
Progressive ratio test 2 breakpoint6.57.29.4-2.92.8-3.02.7-2.92.72.83.1-2.62.4-1.0
Progressive ratio test 2 inactive lever presses4.35.06.7-2.32.5-2.62.2-2.32.32.32.6-2.22.1-0.5
Incentive Sensitization - Responses3.53.64.6-2.02.0-2.11.8-2.02.12.02.0-1.81.7-1.0
Incentive Sensitization - Breakpoint3.33.44.6-2.02.0-2.11.7-1.92.12.01.9-1.71.6-1.0
Sum of active levers in priming session hrs 5-60.60.51.10.8-1.00.6-0.60.5-1.0-0.8-0.90.60.1-0.7
Progressive ratio0.10.10.30.1-0.00.0-0.20.3-0.2-0.3-0.10.6-0.2-0.2
Food seeking constrained by brief footshock3.13.85.8-2.12.4-1.81.7-1.62.42.31.4-2.01.6-1.9
Seeking ratio, punishment vs. effort1.31.62.5-1.31.3-1.11.2-1.21.61.50.9-1.61.2-1.0
Retroperitoneal fat weight1.34.49.1-2.23.0-2.11.7-1.82.92.32.0-2.20.80.8
Reaction time number correct0.60.81.81.0-0.90.6-0.90.8-0.8-0.8-0.91.4-0.90.7
Reaction time mean minus median0.30.40.80.7-0.80.7-0.40.6-0.9-0.6-0.50.4-0.50.7
Reaction time mean minus median AUC1.21.62.41.3-1.51.3-1.11.3-1.5-1.2-1.11.2-1.01.1
Reaction time num false alarms3.54.86.0-2.22.2-2.42.4-2.32.22.32.0-1.92.3-1.8
Reaction time num false alarms AUC3.95.46.9-2.42.4-2.62.5-2.52.42.42.2-2.22.4-1.2
Reaction time trials correct on left0.60.81.81.0-0.90.6-0.90.8-0.8-0.8-0.91.4-0.90.7
Reaction time trials on left0.50.81.70.9-0.90.5-0.90.8-0.8-0.7-0.81.3-0.80.8
Reaction time mean0.70.91.60.8-1.21.1-0.71.0-1.3-0.9-0.70.6-0.81.1
Reaction time mean AUC0.91.22.31.0-1.51.4-0.71.2-1.5-1.1-1.00.7-0.81.0
Median of all reaction times0.60.81.50.7-1.21.1-0.61.0-1.2-0.9-0.70.5-0.71.0
Reaction time omissions0.20.31.2-0.3-0.3-0.10.5-0.3-0.4-0.10.8-0.40.81.1
Reaction time false alarm rate4.05.66.9-2.52.5-2.42.6-2.52.42.42.1-2.52.4-1.5
Reaction time premature initiation rate0.81.12.3-1.00.7-1.10.7-1.30.81.31.5-1.11.3-0.7
Reaction time premature initiations0.20.30.8-0.40.3-0.70.1-0.70.40.80.9-0.30.7-0.3
Std. dev. reaction times0.40.61.60.7-0.90.8-0.40.7-1.0-0.7-0.50.4-0.61.2
Reaction time trials completed0.50.81.70.9-0.90.5-0.90.8-0.8-0.7-0.81.3-0.80.8
Reaction time trials AUC0.60.91.91.0-0.90.6-1.00.9-0.8-0.8-0.91.4-1.00.8
Run reversals in cocaine runway, females0.30.31.40.4-0.50.6-0.10.3-0.6-0.7-0.00.2-0.51.2
Run reversals in cocaine runway, males0.10.10.20.3-0.40.1-0.00.1-0.3-0.2-0.00.40.3-0.3
Latency to leave start box in cocaine runway0.30.30.60.5-0.80.6-0.50.5-0.7-0.5-0.50.6-0.4-0.1
Latency to leave start box in cocaine runway, F0.50.51.00.7-1.00.7-0.50.6-0.9-0.6-0.71.0-0.5-0.4
Latency to leave start box in cocaine runway, M0.10.10.50.1-0.10.3-0.40.2-0.1-0.3-0.2-0.1-0.30.7
Std. dev. time between licks in bursts0.00.00.20.2-0.30.2-0.20.2-0.4-0.20.10.10.2-0.1
Total sessions with >9 infusions0.10.10.3-0.30.5-0.50.2-0.20.40.30.5-0.20.00.5
Short access day 1 total inactive lever presses1.21.42.0-1.31.3-1.21.2-1.21.41.41.2-1.10.80.0
Short access day 10 total inactive lever presses0.70.82.8-0.70.4-0.81.0-0.70.40.60.8-0.91.7-1.0
Short access day 1 total infusions0.80.81.3-0.91.0-1.10.9-0.90.80.91.1-0.91.0-0.4
Short access day 10 total infusions6.06.78.0-2.62.6-2.82.8-2.72.42.72.8-2.72.7-1.4
Short access total infusions3.54.04.9-2.02.0-2.12.2-2.11.72.02.1-2.12.1-1.2
Short access day 1 locomotion2.93.25.2-1.81.8-2.11.7-2.01.61.72.3-1.71.8-0.6
Short access day 10 total locomotion10.211.415.5-3.63.9-3.53.3-3.43.73.93.5-3.62.5-1.1
Short access total locomotion4.95.17.1-2.42.7-2.42.3-2.42.32.62.5-2.41.6-0.8
One hour access (0.3 mA shock)1.21.42.4-1.11.1-1.21.2-1.11.01.21.0-1.01.3-1.5
Compulsive drug intake0.70.71.30.8-0.90.8-0.90.8-0.6-0.9-0.91.1-1.00.4
One hour access (shock baseline)1.21.42.0-1.21.4-1.21.3-1.11.21.31.1-1.31.1-0.8
Social response proportion0.30.40.80.8-0.60.4-0.60.7-0.6-0.5-0.60.9-0.6-0.3
Social responses0.00.10.4-0.20.2-0.20.1-0.10.20.60.1-0.1-0.0-0.3
Social time0.20.31.8-0.20.1-0.40.3-0.40.00.50.4-0.10.5-1.4
Soleus weight0.20.61.4-0.70.8-0.80.8-0.80.60.80.4-0.30.8-1.2
Bone: stiffness0.71.11.9-1.01.2-1.41.0-0.91.31.01.1-0.61.4-0.6
Tibialis anterior weight0.10.21.50.70.10.0-0.40.30.0-0.3-0.50.0-0.1-1.2
Time to tail flick, vehicle, before self-admin0.00.00.30.0-0.3-0.10.0-0.1-0.0-0.1-0.00.50.10.4
Time to tail flick, vehicle, after self-admin0.70.72.0-0.70.3-1.10.7-1.00.40.61.2-0.51.4-0.5
Time to tail flick, test, before self-admin0.60.61.10.9-0.71.0-0.70.9-0.6-0.4-1.10.8-1.0-0.1
Time to tail flick, test, after self-admin0.10.10.30.0-0.50.10.2-0.1-0.3-0.30.30.20.4-0.0
Delta time to tail flick, vehicle, before/after SA1.91.93.1-1.41.2-1.41.4-1.41.01.41.8-1.71.7-0.3
Delta time to tail flick, test, before/after SA0.10.10.4-0.2-0.2-0.30.4-0.2-0.1-0.30.5-0.00.60.1
Tibia length0.10.41.7-0.50.6-0.50.2-0.20.90.60.20.3-0.21.3
Ambulatory time before self-admin0.40.43.50.2-0.3-0.10.30.0-0.20.0-0.30.60.3-1.9
Ambulatory time after self-admin0.40.53.4-0.40.1-0.40.4-0.40.10.60.2-0.00.8-1.8
Bone: tissue strength1.11.01.81.0-0.90.9-1.11.3-0.8-0.6-1.11.3-1.10.9
Total heroin consumption0.81.01.6-1.00.8-0.91.2-1.00.81.10.6-0.91.3-0.9
Bone: trabecular number3.85.98.6-2.82.4-2.52.7-2.82.32.12.9-2.42.31.0
Bone: trabecular spacing1.52.03.11.5-1.11.3-1.61.7-1.0-1.0-1.81.3-1.5-1.3
Bone: trabecular thickness4.85.78.8-2.52.1-2.53.0-2.82.01.92.9-2.32.60.9
Bone: trabecular tissue density1.01.54.71.2-1.20.8-1.31.0-1.2-1.0-0.51.4-0.92.2
Water consumed over 24 hours0.20.20.6-0.40.6-0.30.2-0.20.60.60.2-0.3-0.50.8
Number of responses in last shaping day1.31.32.1-1.21.0-1.21.4-1.50.81.11.4-1.01.1-0.9