Hub : Genes

Taco1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Taco1 0.05 0.03 1.2e-05 0.04 0.04 0.04 0.04 9.8e-06 2.0e-05 6.5e-05 4.8e-05
2 Brain mRNA stability Taco1 0.14 0.06 5.6e-17 0.18 0.17 0.18 0.18 9.2e-17 4.9e-16 1.2e-16 6.1e-17
3 NAcc mRNA stability Taco1 0.13 0.06 0.0e+00 0.15 0.14 0.14 0.15 6.9e-22 3.1e-20 3.0e-21 4.9e-22
4 LHb mRNA stability Taco1 0.18 0.09 1.6e-03 0.09 0.09 0.07 0.09 3.8e-03 3.9e-03 1.0e-02 4.1e-03
5 Liver mRNA stability Taco1 0.09 0.04 6.8e-14 0.1 0.1 0.1 0.11 1.9e-11 1.1e-11 6.5e-11 5.1e-12
6 IC mRNA stability Taco1 0.07 0.04 5.6e-03 0.05 0.05 0.02 0.01 4.1e-03 5.0e-03 5.6e-02 1.7e-01
7 Adipose mRNA stability Taco1 0.08 0.04 3.8e-08 0.06 0.07 0.05 0.06 4.1e-07 6.5e-08 4.9e-06 6.8e-07
8 pVTA mRNA stability Taco1 0.09 0.04 1.9e-08 0.12 0.11 0.1 0.12 5.0e-10 2.9e-09 1.7e-08 2.9e-10
9 Liver gene expression Taco1 0.12 0.05 2.3e-14 0.12 0.1 0.1 0.1 1.8e-13 2.3e-11 1.1e-11 9.5e-12
10 PL mRNA stability Taco1 0.1 0.04 1.9e-10 0.07 0.09 0.07 0.08 1.0e-07 7.5e-10 1.4e-08 1.0e-08
11 BLA mRNA stability Taco1 0.11 0.05 1.2e-07 0.12 0.11 0.11 0.12 6.3e-07 1.5e-06 1.4e-06 1.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.93.55.61.6-1.8-2.01.8-2.21.9-1.6-1.72.2-2.40.5
Area under the delay curve0.10.20.50.1-0.5-0.40.1-0.70.4-0.0-0.60.7-0.2-0.1
BMI with tail0.41.53.61.2-1.4-1.20.7-1.10.8-0.8-1.91.5-0.51.4
BMI without tail1.05.29.02.4-2.7-2.21.6-2.22.0-2.0-3.02.7-1.82.0
Body weight2.912.717.23.8-4.0-3.83.3-3.63.1-3.0-4.13.9-3.03.1
Weight adjusted by age0.41.21.8-1.21.01.0-1.10.9-0.91.31.1-1.11.3-0.9
Bone surface6.613.016.03.8-3.7-3.83.8-4.03.7-3.3-3.33.8-3.92.2
Bone volume5.310.513.43.2-3.3-3.53.4-3.73.3-2.9-3.13.6-3.51.8
Breakpoint value in progressive ratio session0.10.30.50.2-0.2-0.40.7-0.20.7-0.7-0.60.5-0.40.7
Number of licking bursts0.00.00.2-0.10.2-0.40.5-0.20.10.10.1-0.10.2-0.0
Context. condit. distance diff. score0.50.71.4-0.30.71.2-1.10.7-0.60.80.6-0.91.20.1
Locomotion velocity, session 11.82.02.91.6-1.4-1.71.6-1.31.6-1.3-1.11.3-1.70.6
Locomotion distance, session 10.10.10.30.5-0.5-0.50.3-0.20.1-0.2-0.00.2-0.5-0.4
Locomotion velocity, session 20.91.02.40.9-0.7-1.11.5-0.61.1-1.3-0.40.5-1.21.2
Locomotion distance, session 20.10.10.40.2-0.00.3-0.10.4-0.2-0.10.5-0.60.10.1
Locomotion velocity, session 30.10.10.3-0.50.4-0.10.10.4-0.10.40.5-0.40.2-0.6
Locomotion distance, session 30.10.10.50.1-0.2-0.60.7-0.20.3-0.10.00.1-0.30.1
Stereotopy head waving bouts, day 30.10.10.6-0.60.40.1-0.20.10.00.40.20.1-0.1-0.8
Stereotopy head waving duration, day 30.30.41.0-1.00.80.5-0.70.4-0.30.80.4-0.30.7-0.7
Locomotion velocity, session 70.30.30.7-0.80.60.4-0.40.7-0.30.40.6-0.50.3-0.6
Locomotion distance, session 70.20.30.7-0.80.50.4-0.40.6-0.50.30.5-0.60.6-0.2
Stereotopy head waving bouts, day 70.20.20.5-0.40.60.3-0.20.4-0.30.40.7-0.50.1-0.7
Stereotopy head waving duration, day 70.81.01.7-0.91.30.9-0.61.1-0.90.91.3-1.20.7-1.1
Locomotion velocity, session 80.20.31.20.9-0.3-0.50.6-0.30.4-0.3-0.3-0.00.11.1
Locomotion distance, session 80.20.30.60.10.30.7-0.50.5-0.40.20.4-0.80.80.6
Degree of sensitization distance0.10.10.4-0.00.10.5-0.60.3-0.40.10.0-0.30.60.2
Degree of sensitization stereotypy0.60.61.3-0.50.90.8-0.50.9-0.80.61.1-1.10.4-0.8
Conditioned locomotion0.20.20.90.0-0.3-0.20.1-0.40.0-0.6-0.70.4-0.10.9
Cocaine response after cond. corrected0.20.30.9-0.60.20.3-0.30.0-0.10.80.6-0.40.5-1.0
Cocaine response after cond. not corrected0.10.20.9-0.40.20.10.1-0.10.30.50.7-0.3-0.0-1.0
Cocaine response before conditioning0.20.20.60.2-0.1-0.40.7-0.20.6-0.5-0.00.2-0.8-0.0
Saline control response1.01.45.00.8-0.9-0.80.9-0.90.9-1.5-1.40.9-0.72.2
Bone: connectivity density2.84.56.52.0-2.1-2.22.1-2.42.3-2.0-1.92.3-2.51.1
Bone: cortical apparent density3.55.57.6-2.52.22.3-2.72.4-2.52.32.0-1.91.9-2.8
Bone: cortical area1.82.94.51.5-1.8-2.11.9-1.91.6-1.2-1.62.1-2.00.4
Bone: cortical porosity11.913.019.53.3-3.4-3.94.4-3.64.4-3.5-2.93.3-4.02.6
Bone: cortical porosity8.99.814.03.0-3.0-3.43.7-3.33.6-2.8-2.73.1-3.42.1
Bone: cortical thickness2.94.814.8-2.52.11.3-1.72.0-2.22.52.1-1.31.0-3.8
Bone: cortical thickness1.82.25.8-1.81.51.2-1.21.5-1.31.41.6-1.00.5-2.4
Bone: cortical tissue density3.35.37.2-2.52.22.3-2.62.4-2.52.22.0-1.81.8-2.7
Condit. Reinf. active minus inactive responses3.33.74.51.7-1.8-1.82.0-1.92.1-2.1-1.91.9-1.82.1
Condit. Reinf. active-inactive response ratio1.41.52.21.1-1.2-0.91.1-1.21.4-1.3-1.21.2-1.21.5
Condit. Reinf. active responses3.74.86.02.0-2.0-2.22.3-2.12.2-2.3-2.32.1-1.92.5
Condit. Reinf. inactive responses1.11.42.21.2-1.1-1.51.3-1.21.0-1.1-1.31.2-0.91.0
Incentive salience index mean3.64.65.52.1-2.0-2.12.3-2.02.2-2.3-2.02.1-2.32.1
Condit. Reinf. lever presses1.01.62.71.5-1.0-1.51.7-0.80.9-1.5-1.01.0-1.61.0
Condit. Reinf. active minus inactive responses6.710.313.03.0-3.3-3.33.5-3.63.5-3.1-3.13.2-3.12.7
Condit. Reinf. active-inactive response ratio4.26.78.62.3-2.5-2.72.9-2.82.9-2.6-2.32.5-2.72.0
Condit. Reinf. active responses7.811.213.03.0-3.4-3.33.4-3.63.4-3.4-3.43.4-3.13.2
Condit. Reinf. inactive responses1.42.03.31.1-1.5-1.31.3-1.41.1-1.6-1.81.5-1.11.8
Condit. Reinf. lever presses2.63.84.82.0-2.0-2.02.2-1.81.9-2.2-1.81.8-2.11.9
Condit. Reinf. lever reinforcers received7.310.212.02.8-3.3-3.23.3-3.53.3-3.3-3.23.2-3.03.0
Conditioned reinforcement - actives0.10.51.01.0-0.9-0.70.6-0.70.6-0.6-0.50.3-0.40.9
Conditioned reinforcement - inactives0.51.42.01.4-1.3-1.21.1-1.11.4-1.1-1.01.0-1.20.9
Conditioned locomotion2.84.15.42.3-2.3-2.01.9-2.12.2-2.1-1.71.7-2.02.0
Patch foraging indifference point 0 sec2.05.77.62.1-2.5-2.32.1-2.72.3-2.4-2.72.5-2.02.3
Patch foraging indifference point AUC0.30.71.41.2-1.0-0.50.4-0.80.7-0.7-1.00.7-0.41.1
Delay disc. indifference point, 0s delay0.40.41.0-1.00.70.5-0.70.3-0.60.80.3-0.30.8-0.7
Delay disc. indifference point, 16s delay0.40.61.30.3-0.9-0.90.6-1.20.8-0.4-1.01.1-0.50.4
Delay disc. indifference point, 2s delay0.60.71.80.7-0.9-0.80.5-1.30.8-0.4-1.11.2-0.60.2
Delay disc. indifference point, 24s delay0.91.52.11.2-1.4-1.41.0-1.41.1-0.9-1.41.4-0.91.0
Delay disc. indifference point, 4s delay0.20.30.7-0.80.50.3-0.40.2-0.10.70.6-0.30.2-0.9
Delay disc. indifference point, 8s delay0.00.10.3-0.2-0.2-0.1-0.2-0.20.10.2-0.30.5-0.2-0.6
Indifference point function ln k0.10.21.0-0.90.4-0.40.30.0-0.10.20.20.1-0.1-1.0
Indifference point function log k0.10.21.0-0.90.4-0.40.30.0-0.10.20.20.1-0.1-1.0
Patch foraging total patch changes 0 sec2.16.38.42.2-2.7-2.52.2-2.92.4-2.5-2.92.7-2.12.3
Patch foraging total patch changes 12 sec3.44.68.32.5-2.3-1.71.7-2.21.8-2.4-2.31.8-1.52.9
Patch foraging total patch changes 18 sec1.43.44.31.8-2.0-1.61.6-2.01.9-2.0-2.01.7-1.52.1
Patch foraging total patch changes 24 sec1.55.16.72.2-2.6-1.91.8-2.62.4-2.2-2.52.5-2.11.9
Patch foraging total patch changes 6 sec2.23.74.51.7-2.1-1.91.8-2.12.0-1.9-2.12.0-1.71.8
Patch foraging time to switch 0 sec0.10.30.7-0.70.90.20.10.8-0.60.30.8-0.70.2-0.4
Patch foraging water rate 0 sec0.83.04.31.8-2.1-1.71.4-1.91.5-1.6-2.12.0-1.61.4
Patch foraging water rate 12 sec0.20.72.9-1.00.70.5-0.70.5-0.51.10.8-0.30.4-1.7
Patch foraging water rate 18 sec0.10.20.40.2-0.5-0.30.2-0.60.4-0.1-0.20.5-0.6-0.5
Patch foraging water rate 24 sec0.00.00.20.10.00.1-0.0-0.1-0.30.30.2-0.20.2-0.4
Patch foraging water rate 6 sec0.30.40.90.2-0.6-0.60.4-0.90.7-0.3-0.61.0-0.9-0.6
Seeking ratio, delayed vs. immediate footshock0.10.20.50.10.30.7-0.70.5-0.50.20.1-0.20.40.3
Distance traveled before self-admin0.20.31.0-1.00.5-0.00.20.1-0.10.80.7-0.40.4-0.9
Distance traveled after self-admin0.00.10.3-0.20.30.4-0.10.0-0.00.40.2-0.20.5-0.0
Extensor digitorum longus weight2.710.617.2-3.43.43.1-3.63.4-4.13.32.3-2.93.9-1.8
Bone: elastic displacement0.91.13.1-0.91.10.9-1.01.1-0.71.21.2-0.80.5-1.8
Bone: elastic work0.30.41.40.6-0.6-0.70.5-0.40.4-0.3-0.30.7-1.2-0.6
Bone: endosteal estimation14.435.239.36.3-6.2-5.86.1-6.16.1-6.1-5.75.4-5.46.0
Bone: endosteal perimeter14.735.942.06.5-6.3-5.96.1-6.56.1-5.7-5.95.6-5.16.1
Epididymis fat weight0.20.81.20.9-1.0-1.00.7-0.90.8-0.7-1.10.9-0.60.8
Delta time in closed arm before/after self-admin0.10.10.2-0.10.10.2-0.10.3-0.30.20.4-0.2-0.2-0.5
Delta time in open arm before/after self-admin0.20.21.0-0.50.50.3-0.50.4-0.50.30.0-0.41.00.0
Diff in mean of infusions in LGA sessions1.42.53.4-1.61.81.6-1.51.9-1.61.41.6-1.61.4-1.3
Delay discount exponential model param0.20.30.7-0.30.60.5-0.20.8-0.50.10.7-0.80.3-0.1
Extinction: sum of active levers before priming0.10.10.5-0.50.30.3-0.30.2-0.10.2-0.2-0.10.70.3
Active lever presses in extinction session 61.91.93.11.0-1.2-1.41.5-1.31.8-1.4-1.51.5-1.21.3
Bone: final force1.01.62.41.1-1.4-1.61.5-1.51.2-0.7-0.91.4-1.5-0.1
Bone: final moment1.11.82.81.2-1.5-1.71.6-1.61.2-0.8-1.01.5-1.7-0.1
Food consumed during 24 hour testing period1.32.64.62.2-1.5-1.71.5-1.41.3-1.6-1.91.5-1.11.9
Glucose1.32.13.1-1.51.51.2-1.11.4-1.21.81.6-1.51.6-1.4
Heart weight0.20.41.5-0.30.20.5-0.80.1-0.51.10.20.00.6-1.2
Delay discount hyperbolic model param0.20.30.7-0.30.60.5-0.20.9-0.60.20.7-0.80.4-0.1
Intermittent access intake day 1-15 change0.00.10.5-0.10.30.00.10.5-0.40.20.5-0.70.40.3
Intermittent access intake escalation0.00.10.60.4-0.2-0.40.5-0.00.0-0.2-0.0-0.20.10.8
Intermittent access intake escalation 20.10.20.90.6-0.3-0.50.7-0.20.2-0.5-0.20.0-0.20.9
Intermitt. access day 1 inactive lever presses0.45.36.62.2-2.3-2.42.4-2.12.3-2.6-2.32.2-2.42.2
Intermitt. access day 15 inactive lever presses0.63.04.91.2-1.7-2.01.8-1.51.9-2.2-1.51.6-2.21.3
Intermitt. access escalation Index1.03.24.3-1.91.91.9-1.71.5-1.52.11.8-1.72.0-1.5
Intermittent access day 1 total infusions0.41.31.91.4-1.2-1.21.2-1.21.3-1.0-1.00.8-0.90.8
Intermittent access day 15 total infusions0.61.42.51.6-1.4-1.31.2-1.21.2-1.0-1.10.8-0.61.4
Intermittent access terminal intake (last 3 days)1.62.94.82.2-1.9-1.81.7-1.71.7-1.6-1.51.1-1.22.0
Intermittent access total infusions2.32.75.12.3-1.9-1.61.6-1.71.6-1.5-1.51.1-1.11.8
Intermittent access day 1 locomotion3.15.77.62.8-2.6-2.32.3-2.42.7-2.3-2.32.2-2.42.0
Intermittent access day 15 total locomotion1.56.010.93.3-2.6-2.32.2-2.42.4-2.4-2.42.1-2.02.6
Intermittent access total locomotion7.89.315.13.9-3.3-2.92.9-3.03.1-3.1-2.82.6-2.93.0
Intermittent access standard deviation0.20.81.91.4-0.9-0.90.9-0.50.6-1.1-0.80.6-1.00.9
Left kidney weight0.00.21.3-0.1-0.10.0-0.10.0-0.00.60.30.1-0.1-1.1
Right kidney weight0.00.30.80.7-0.7-0.40.1-0.50.30.3-0.20.5-0.5-0.9
Cocaine induced anxiety0.10.21.1-0.40.20.4-0.40.2-0.10.40.5-0.1-0.2-1.1
Post-drug Anxiety0.40.41.7-0.50.40.7-0.70.5-0.40.70.6-0.30.0-1.3
Baseline Anxiety0.10.20.3-0.30.40.5-0.50.5-0.50.40.2-0.20.3-0.4
Tail length2.412.915.23.9-3.8-3.73.5-3.43.6-3.7-3.43.6-3.92.9
Length with tail2.29.814.73.8-3.4-3.33.2-3.22.8-2.8-3.13.1-2.92.6
Length without tail0.10.41.21.1-0.8-0.90.7-0.70.2-0.3-0.60.6-0.40.6
Times rat made contact with spout0.91.12.71.7-1.1-0.80.9-0.90.9-1.0-1.01.0-1.10.9
Lifetime Intake2.73.45.22.3-2.0-1.91.8-1.91.9-1.8-1.71.4-1.41.9
Liver weight, left5.18.713.53.7-3.0-2.83.2-2.93.0-2.8-2.72.7-2.92.6
Liver weight, right0.20.42.9-0.40.20.1-0.10.4-0.50.50.7-0.2-0.5-1.7
Locomotor activity0.40.61.41.2-1.0-0.50.8-0.81.0-1.0-0.30.1-0.60.9
Locomotor testing distance0.61.42.31.4-1.4-0.91.2-1.11.5-1.5-0.80.5-1.11.4
Locomotor testing rearing0.31.33.11.4-1.1-0.50.9-0.71.3-1.7-0.60.2-1.11.8
Locomotion in novel chamber0.10.10.40.6-0.20.20.1-0.00.20.20.6-0.4-0.3-0.4
Locomotion in novel chamber post-restriction0.51.63.71.1-1.4-1.21.1-1.91.5-0.7-1.41.5-0.70.6
Fecal boli incidents, locomotor time 10.00.10.3-0.60.20.0-0.1-0.00.10.20.1-0.10.50.3
Change in fecal boli incidents, locomotor task0.10.10.5-0.10.10.3-0.60.4-0.70.40.1-0.10.2-0.4
Time >=10cm from walls, locomotor time 12.63.23.8-1.61.81.9-1.71.7-1.61.91.9-1.91.9-1.6
Bouts of movement, locomotor time 10.20.30.5-0.70.70.5-0.70.7-0.60.40.1-0.10.2-0.7
Total resting periods, locomotor time 10.30.30.6-0.70.70.5-0.70.7-0.60.40.2-0.10.2-0.8
Rest time, locomotor task time 10.00.10.3-0.60.30.1-0.00.10.00.00.1-0.0-0.1-0.4
Distance moved, locomotor task time 10.10.41.11.1-0.6-0.60.4-0.40.3-0.5-0.60.6-0.60.6
Vertical activity count, locomotor time 10.10.40.80.9-0.7-0.80.7-0.60.4-0.5-0.50.6-0.70.5
Time >=10cm from walls, locomotor time 20.00.10.5-0.10.20.10.10.20.30.10.7-0.6-0.2-0.5
Bouts of movement, locomotor time 20.10.41.2-1.10.80.4-0.50.6-0.90.60.2-0.10.5-0.6
Total resting periods, locomotor time 20.20.71.8-1.31.00.7-0.80.8-1.10.80.4-0.30.7-0.8
Rest time, locomotor task time 22.74.58.0-2.82.42.2-2.21.9-2.02.31.4-1.32.3-1.9
Distance moved, locomotor task time 20.81.02.31.5-0.9-1.01.1-0.60.8-1.2-0.50.6-1.50.7
Vertical activity count, locomotor time 21.74.05.82.1-2.0-2.22.3-1.62.0-2.4-1.41.5-2.41.7
Light reinforcement 10.10.41.5-0.3-0.4-0.80.3-0.70.2-0.5-1.21.1-0.20.1
Light reinforcement 20.30.71.70.2-0.8-1.00.6-1.10.6-0.7-1.21.3-0.80.2
Bone: marrow area13.934.138.46.2-6.1-5.66.0-6.06.1-6.0-5.65.3-5.45.9
Bone: maximum diameter5.511.014.63.2-3.5-3.73.7-3.83.3-2.8-3.23.4-3.12.4
Bone: maximum force1.52.94.41.6-2.0-2.11.8-2.11.4-1.1-1.51.9-1.80.3
Bone: maximum moment1.73.25.01.7-2.1-2.22.0-2.11.5-1.3-1.62.0-2.00.3
Mean time between licks in bursts0.00.00.10.1-0.3-0.1-0.2-0.20.00.3-0.20.10.30.1
Mean num. licks in bursts0.10.30.80.9-0.7-0.1-0.1-0.20.3-0.6-0.70.7-0.60.5
Cd content in liver5.25.78.9-2.12.43.0-3.02.6-2.32.22.1-2.42.5-1.2
Co content in liver1.92.23.0-1.21.61.7-1.71.6-1.51.51.5-1.71.7-0.5
Cu content in liver0.60.71.20.4-0.7-1.11.0-0.80.7-0.9-0.90.9-0.80.6
Fe content in liver0.00.10.20.20.00.10.30.00.2-0.30.3-0.3-0.10.4
K content in liver0.40.30.80.6-0.4-0.80.9-0.70.2-0.5-0.50.3-0.20.7
Mg content in liver0.40.41.1-0.70.90.5-0.50.6-1.00.50.5-0.70.7-0.2
Mn content in liver0.10.10.2-0.20.2-0.40.4-0.2-0.0-0.00.2-0.0-0.2-0.3
Na content in liver0.50.61.40.7-0.5-0.81.0-0.80.7-0.8-0.70.6-0.41.2
Rb content in liver3.44.05.3-2.02.31.9-1.72.0-2.22.02.2-2.11.8-1.9
Se content in liver1.31.52.8-1.21.21.3-1.41.0-1.21.50.9-1.01.7-0.9
Sr content in liver1.00.81.20.8-1.0-1.00.9-1.01.0-0.7-1.01.1-0.90.5
Zn content in liver0.30.40.7-0.70.50.6-0.60.3-0.40.80.6-0.50.6-0.8
Bone: minimum diameter13.926.730.45.4-5.5-5.35.2-5.55.2-4.8-5.25.2-4.74.7
Time in familiar zone, hab. session 10.20.21.40.5-0.30.00.0-0.30.1-0.4-0.50.10.21.2
Time in novel zone, hab. session 10.40.52.0-1.00.80.3-0.40.6-0.20.70.8-0.30.1-1.4
Total zone transitions, hab. session 10.10.10.40.6-0.3-0.40.30.10.0-0.10.0-0.2-0.10.1
Total locomotion distance, hab. session 11.01.42.71.5-1.3-1.41.3-0.91.1-1.2-0.81.0-1.60.3
Locomotion velocity, hab. session 11.31.83.21.8-1.6-1.61.4-1.11.2-1.3-1.01.1-1.70.6
Time in familiar zone, hab. session 20.50.53.01.1-0.6-0.10.3-0.40.6-0.8-0.50.1-0.01.7
Time in novel zone, hab. session 20.50.63.7-1.10.40.0-0.30.1-0.40.70.40.1-0.2-1.9
Total zone transitions, hab. session 20.10.10.40.50.10.0-0.00.3-0.3-0.00.3-0.60.30.3
Total locomotion distance, hab. session 20.20.20.70.8-0.5-0.50.3-0.30.2-0.7-0.40.2-0.50.5
Locomotion velocity, hab. session 20.10.20.70.8-0.5-0.40.2-0.20.1-0.5-0.30.1-0.40.4
Novel to familiar place preference ratio0.40.51.10.4-0.7-0.80.7-0.80.7-0.4-0.91.1-0.60.2
Novelty place preference0.20.30.60.2-0.5-0.60.5-0.60.5-0.2-0.60.8-0.50.1
Time in novel zone, NPP test0.20.20.50.2-0.4-0.50.5-0.50.6-0.2-0.50.7-0.5-0.0
Total zone transitions, NPP test0.00.10.20.5-0.1-0.30.20.1-0.30.00.2-0.40.0-0.2
Total locomotion distance, NPP test0.60.81.91.4-1.1-1.00.9-0.80.7-1.0-0.60.6-1.20.3
Locomotion velocity, NPP test0.20.30.80.9-0.8-0.80.5-0.50.3-0.6-0.50.4-0.70.2
Intraocular pressure0.30.40.8-0.0-0.9-0.90.5-0.70.8-0.5-0.90.9-0.40.5
Delta distance traveled before/after self-admin0.20.20.70.10.40.8-0.70.5-0.40.1-0.1-0.00.40.3
Delta ambulatory time before/after self-admin0.10.10.30.40.00.4-0.40.1-0.2-0.2-0.30.20.10.6
Parametrial fat weight0.51.21.91.0-1.2-1.31.1-1.21.1-0.7-1.01.4-1.4-0.1
Pavlov. Cond. lever latency3.13.96.3-2.31.82.4-2.51.6-1.82.01.6-1.72.3-1.6
Pavlov. Cond. magazine entry latency5.77.49.52.8-2.5-3.03.1-2.52.6-2.8-2.62.7-2.92.4
Pavlov. Cond. change in total contacts5.05.48.52.2-2.0-2.82.9-1.92.2-2.5-2.12.2-2.62.1
Pavlov. Cond. index score5.06.49.02.7-2.3-2.93.0-2.22.3-2.5-2.32.4-2.72.3
Pavlov. Cond. latency score4.05.17.42.5-2.1-2.62.7-2.02.1-2.3-2.12.1-2.32.1
Pavlov. Cond. lever contacts3.94.77.12.5-1.9-2.52.7-1.72.0-2.3-1.81.9-2.51.8
Pavlov. Cond. magazine entry number4.35.57.3-2.32.12.6-2.72.1-2.22.52.2-2.32.5-2.2
Pavlov. Cond. intertrial magazine entries0.30.41.10.2-0.8-0.40.1-0.80.4-0.5-0.90.60.21.0
Pavlov. Cond. lever-magazine prob. diff.5.36.69.62.6-2.4-3.03.1-2.32.4-2.5-2.32.5-2.72.2
Pavlov. Cond. response bias7.99.813.63.2-2.9-3.63.7-2.83.0-3.2-2.83.1-3.62.3
Pavlov. Cond. lever latency0.50.70.9-0.90.90.8-0.90.9-0.80.80.7-0.70.7-0.8
Pavlov. Cond. magazine entry latency2.43.34.2-1.71.81.7-1.51.7-1.92.02.0-2.02.0-1.5
Pavlov. Cond. change in total contacts0.20.51.80.8-0.7-0.50.7-0.70.7-0.8-0.60.3-0.21.4
Pavlov. Cond. index score0.00.00.10.2-0.0-0.00.3-0.10.10.00.2-0.20.20.2
Pavlov. Cond. latency score0.00.00.20.00.10.00.20.00.00.20.4-0.40.2-0.0
Pavlov. Cond. lever contacts0.30.40.50.7-0.7-0.60.7-0.70.6-0.7-0.60.5-0.50.7
Pavlov. Cond. magazine entry number3.24.25.71.8-2.0-2.11.8-1.91.9-2.1-2.42.3-2.01.9
Pavlov. Cond. intertrial magazine entries8.719.023.54.0-4.5-4.64.2-4.34.1-4.4-4.84.7-4.14.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.1-0.00.10.10.10.0-0.10.20.3-0.40.30.0
Pavlov. Cond. response bias0.00.00.10.3-0.20.00.1-0.20.1-0.10.0-0.10.10.3
Time in closed arm before self-admin0.00.00.10.30.10.10.10.10.3-0.2-0.30.3-0.3-0.1
Time in closed arm after self-admin0.40.51.1-0.10.71.1-0.80.9-0.60.70.6-0.50.4-0.7
Time in open arm before self-admin0.81.01.8-1.00.81.0-0.90.7-0.81.21.4-1.00.7-1.3
Time in open arm after self-admin0.00.10.3-0.2-0.0-0.1-0.0-0.2-0.00.10.0-0.20.60.2
Bone: periosteal estimation10.224.327.65.0-5.2-5.25.2-5.35.0-4.7-4.74.9-4.84.1
Bone: periosteal perimeter5.611.114.43.5-3.6-3.63.7-3.83.4-2.7-3.23.4-3.12.5
Bone: post-yield work1.32.23.01.7-1.6-1.51.6-1.51.5-1.3-1.31.4-1.41.2
Progressive ratio test 1 active lever presses2.13.74.42.0-2.1-2.12.0-2.12.1-1.8-1.91.8-1.71.6
Progressive ratio test 1 breakpoint2.54.35.12.1-2.2-2.32.1-2.22.1-2.0-2.12.0-1.91.7
Progressive ratio test 1 inactive lever presses1.84.85.72.2-2.4-2.42.3-2.32.4-2.2-2.01.9-1.92.0
Progressive ratio test 2 active lever presses4.86.88.52.6-2.9-2.82.6-2.92.6-2.4-2.62.5-2.22.3
Progressive ratio test 2 breakpoint5.67.29.02.7-3.0-2.92.7-3.02.7-2.5-2.72.6-2.32.4
Progressive ratio test 2 inactive lever presses1.23.74.52.0-2.1-2.11.7-2.11.9-1.8-2.01.9-1.71.6
Incentive Sensitization - Responses1.43.95.22.0-2.3-2.12.0-2.31.9-1.7-2.01.9-1.52.0
Incentive Sensitization - Breakpoint1.73.85.12.1-2.3-2.01.9-2.31.9-1.7-1.91.8-1.52.0
Sum of active levers in priming session hrs 5-61.11.02.2-1.51.30.8-0.71.0-0.80.80.9-1.11.4-0.3
Progressive ratio0.00.10.40.2-0.1-0.20.2-0.4-0.00.2-0.70.60.30.3
Food seeking constrained by brief footshock2.63.36.22.5-1.6-1.31.6-1.62.0-2.0-1.71.2-1.32.5
Seeking ratio, punishment vs. effort0.71.62.81.5-1.3-1.01.1-1.01.6-1.7-0.70.6-1.41.6
Retroperitoneal fat weight0.52.22.71.7-1.6-1.61.4-1.31.2-1.5-1.71.6-1.60.8
Reaction time number correct0.20.61.8-0.80.60.6-0.80.3-0.71.20.6-0.40.9-1.3
Reaction time mean minus median0.00.30.5-0.70.70.6-0.60.6-0.50.40.6-0.50.2-0.5
Reaction time mean minus median AUC0.21.62.1-1.51.41.3-1.31.1-1.11.31.4-1.21.1-1.3
Reaction time num false alarms3.05.06.72.6-2.3-2.42.4-2.52.2-2.0-2.32.1-1.82.0
Reaction time num false alarms AUC2.65.97.72.8-2.5-2.52.5-2.72.4-2.2-2.52.4-2.12.1
Reaction time trials correct on left0.20.61.8-0.80.60.6-0.80.3-0.71.20.6-0.40.9-1.3
Reaction time trials on left0.20.61.8-0.70.50.6-0.80.3-0.61.20.5-0.30.8-1.4
Reaction time mean0.40.91.7-1.21.20.9-0.81.0-0.70.61.3-1.10.5-0.9
Reaction time mean AUC0.61.42.4-1.51.51.2-0.91.2-0.80.81.6-1.40.7-1.0
Median of all reaction times0.60.91.7-1.21.20.9-0.71.0-0.60.61.3-1.10.5-1.0
Reaction time omissions0.30.51.40.2-0.7-0.60.5-0.80.7-0.7-0.50.9-1.2-0.2
Reaction time false alarm rate4.15.77.32.7-2.3-2.42.6-2.32.3-2.4-2.32.1-2.22.4
Reaction time premature initiation rate0.71.12.20.7-1.2-0.90.7-1.21.1-1.0-1.51.5-1.00.7
Reaction time premature initiations0.20.51.30.3-0.8-0.50.2-1.00.7-0.4-1.11.2-0.40.1
Std. dev. reaction times0.10.40.7-0.80.80.6-0.60.7-0.60.40.8-0.70.2-0.6
Reaction time trials completed0.20.61.8-0.70.50.6-0.80.3-0.61.20.5-0.30.8-1.4
Reaction time trials AUC0.20.61.8-0.70.60.6-0.80.4-0.81.20.6-0.40.9-1.3
Run reversals in cocaine runway, females0.20.20.8-0.50.3-0.2-0.20.4-0.30.30.5-0.3-0.2-0.9
Run reversals in cocaine runway, males0.00.10.2-0.40.10.1-0.10.0-0.20.40.20.00.1-0.4
Latency to leave start box in cocaine runway0.20.30.4-0.70.50.5-0.50.4-0.50.50.6-0.50.3-0.6
Latency to leave start box in cocaine runway, F0.30.41.0-0.90.70.5-0.40.5-0.40.70.8-0.50.3-1.0
Latency to leave start box in cocaine runway, M0.00.00.20.1-0.10.2-0.20.0-0.2-0.3-0.0-0.20.10.4
Std. dev. time between licks in bursts0.00.10.2-0.30.20.1-0.30.4-0.50.20.2-0.30.30.1
Total sessions with >9 infusions0.10.10.20.5-0.4-0.40.3-0.30.4-0.2-0.20.1-0.10.2
Short access day 1 total inactive lever presses1.83.54.71.9-2.1-1.91.8-1.92.1-1.8-1.71.8-2.21.1
Short access day 10 total inactive lever presses0.00.20.4-0.2-0.4-0.60.3-0.30.2-0.4-0.40.5-0.50.1
Short access day 1 total infusions0.20.40.70.5-0.6-0.80.7-0.80.8-0.5-0.50.5-0.40.4
Short access day 10 total infusions2.13.44.42.1-1.9-2.12.0-1.92.0-1.9-1.61.4-1.61.8
Short access total infusions1.31.92.51.4-1.3-1.61.5-1.51.6-1.4-1.21.1-1.21.2
Short access day 1 locomotion1.22.02.91.2-1.6-1.71.4-1.51.5-1.3-1.31.4-1.31.2
Short access day 10 total locomotion2.08.210.93.3-2.8-2.62.6-2.63.0-3.1-2.92.7-2.83.0
Short access total locomotion2.43.74.62.1-2.0-2.01.8-1.82.0-1.9-1.81.8-1.91.8
One hour access (0.3 mA shock)1.11.32.11.1-1.1-1.41.4-1.21.2-1.0-0.90.8-0.71.3
Compulsive drug intake0.40.61.4-0.90.70.8-0.70.4-0.51.00.7-0.40.6-1.2
One hour access (shock baseline)0.61.62.81.5-1.3-1.51.4-1.11.1-1.3-1.00.7-0.81.7
Social response proportion0.30.40.7-0.40.60.4-0.40.7-0.80.80.5-0.60.8-0.5
Social responses0.00.00.20.2-0.2-0.10.10.0-0.0-0.10.0-0.20.10.4
Social time0.00.10.30.1-0.2-0.20.3-0.20.5-0.00.00.1-0.10.1
Soleus weight0.10.40.80.7-0.7-0.80.8-0.90.3-0.3-0.60.7-0.50.5
Bone: stiffness0.30.51.11.0-1.0-1.00.9-1.00.4-0.4-0.60.5-0.40.4
Tibialis anterior weight0.10.30.9-0.20.3-0.1-0.30.4-0.90.2-0.5-0.00.70.9
Time to tail flick, vehicle, before self-admin0.10.20.6-0.2-0.2-0.00.1-0.50.30.30.8-0.5-0.3-0.7
Time to tail flick, vehicle, after self-admin0.10.10.5-0.2-0.4-0.30.1-0.70.30.2-0.30.40.1-0.3
Time to tail flick, test, before self-admin0.20.20.4-0.10.60.6-0.30.7-0.20.10.5-0.60.20.1
Time to tail flick, test, after self-admin0.00.00.10.00.0-0.20.2-0.20.3-0.1-0.20.2-0.10.0
Delta time to tail flick, vehicle, before/after SA1.11.22.60.9-0.9-1.10.9-0.91.0-1.1-1.61.5-0.71.0
Delta time to tail flick, test, before/after SA0.00.00.20.0-0.1-0.30.2-0.40.00.1-0.20.10.2-0.1
Tibia length0.10.20.90.7-0.6-0.30.2-0.5-0.10.3-0.00.3-0.4-0.9
Ambulatory time before self-admin0.00.10.4-0.50.1-0.10.3-0.10.00.50.20.00.2-0.6
Ambulatory time after self-admin0.00.00.1-0.00.00.10.1-0.20.10.0-0.30.40.00.1
Bone: tissue strength1.51.62.2-1.01.11.1-1.11.2-1.51.41.5-1.31.2-1.5
Total heroin consumption0.70.81.90.9-0.8-0.71.2-0.91.4-1.0-0.50.5-0.90.9
Bone: trabecular number2.95.47.22.0-2.3-2.52.4-2.72.6-2.1-2.12.6-2.71.1
Bone: trabecular spacing1.21.83.2-0.91.31.5-1.31.6-1.51.11.2-1.71.8-0.1
Bone: trabecular thickness4.36.09.41.7-2.5-2.92.5-2.82.4-2.0-2.53.1-2.90.7
Bone: trabecular tissue density0.71.24.4-1.10.80.7-1.10.7-1.01.40.9-0.50.7-2.1
Water consumed over 24 hours0.10.20.70.8-0.4-0.40.3-0.30.1-0.4-0.40.5-0.6-0.0
Number of responses in last shaping day0.30.40.90.2-0.7-0.80.8-0.71.0-0.6-0.10.4-1.00.0