Syngap1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Syngap1 0.04 0.03 1.9e-03 0.01 0.01 0.01 0.01 1.4e-02 1.8e-02 1.3e-02 6.6e-02
2 BLA intron excision ratio chr20_5035618_5039363 0.21 0.11 4.5e-04 0 0.02 0.03 0.01 2.1e-01 1.8e-02 1.7e-02 5.0e-02
3 BLA intron excision ratio chr20_5035802_5039363 0.13 0.06 4.4e-04 0 -0 -0 0 2.2e-01 3.7e-01 8.3e-01 2.7e-01
4 PL intron excision ratio chr20_5035802_5039363 0.04 0.02 1.2e-03 0.02 0.01 0.02 0.01 1.8e-03 8.4e-03 2.3e-03 4.6e-02
5 Brain isoform ratio NM_001113409.3 0.06 0.04 5.5e-04 0.02 0.04 0.03 0.02 5.8e-03 1.8e-04 1.3e-03 1.1e-02
6 IC isoform ratio NM_001113409.3 0.07 0.05 8.0e-03 0 0.02 0 0 2.9e-01 7.1e-02 2.6e-01 3.1e-01
7 Brain alternative TSS NM_181092.5 0.06 0.04 4.6e-04 0.02 0.04 0.02 0.02 4.9e-03 1.3e-04 4.8e-03 6.3e-03
8 Brain alternative TSS NM_001113409.3 0.06 0.04 4.5e-04 0.02 0.04 0.02 0.02 5.4e-03 1.8e-04 6.8e-03 7.6e-03
9 IC alternative TSS NM_181092.5 0.16 0.09 4.4e-05 0.04 0.08 0.07 0.07 6.7e-03 3.1e-04 6.4e-04 9.1e-04
10 IC alternative TSS NM_001113409.3 0.17 0.09 2.8e-05 0.05 0.08 0.07 0.06 3.5e-03 2.1e-04 6.9e-04 1.2e-03
11 IC intron excision ratio chr20_5035618_5039363 0.19 0.09 3.9e-05 0.07 0.03 0.03 0.04 5.4e-04 2.4e-02 1.4e-02 6.3e-03
12 Brain gene expression Syngap1 0.09 0.05 4.0e-05 0.03 0.04 0.04 0.04 7.6e-04 3.3e-04 2.1e-04 1.9e-04
13 NAcc intron excision ratio chr20_5035802_5039363 0.04 0.02 2.8e-04 0.03 0.02 0.01 0.02 7.8e-05 4.9e-04 2.7e-03 4.5e-04
14 Liver gene expression Syngap1 0.05 0.03 1.7e-05 0.02 0.03 0.03 0.02 5.6e-03 1.0e-04 1.2e-04 1.5e-03
15 Brain mRNA stability Syngap1 0.06 0.04 5.6e-04 0 0.01 0.01 0.01 2.0e-01 1.5e-02 2.3e-02 5.1e-02
16 RMTg isoform ratio NM_181092.5 0.13 0.08 9.5e-03 0.02 0.06 0.05 0.01 8.2e-02 1.4e-02 1.5e-02 2.2e-01
17 NAcc intron excision ratio chr20_5035618_5039363 0.11 0.1 1.7e-06 0.01 0.03 0.02 0.04 2.5e-03 1.4e-05 2.3e-04 1.0e-06
18 PL gene expression Syngap1 0.05 0.03 3.3e-05 0.05 0.04 0.05 0.04 4.6e-06 1.0e-05 6.0e-06 2.1e-05
19 NAcc gene expression Syngap1 0.03 0.02 1.8e-03 0.01 0.01 0.02 0.01 2.3e-03 2.9e-02 1.3e-03 1.4e-02
20 RMTg alternative TSS NM_001113409.3 0.14 0.08 6.5e-03 0.01 0.02 0.06 0.02 1.3e-01 9.0e-02 1.0e-02 9.3e-02
21 RMTg mRNA stability Syngap1 0.21 0.1 5.8e-04 0.18 0.13 0.17 0.18 1.2e-05 2.7e-04 3.1e-05 1.4e-05
22 BLA gene expression Syngap1 0.09 0.07 8.7e-03 0.04 0.02 0.03 0.04 1.9e-03 4.0e-02 1.1e-02 2.1e-03
23 BLA mRNA stability Syngap1 0.13 0.07 1.4e-04 0.08 0.04 0.05 0.06 4.2e-05 2.0e-03 1.5e-03 4.8e-04
24 RMTg alternative TSS NM_181092.5 0.18 0.1 2.0e-03 0.03 0.04 0.07 0.03 6.6e-02 3.0e-02 5.3e-03 5.3e-02
25 Brain intron excision ratio chr20_5047915_5048243 0.05 0.03 8.5e-03 0.02 0 0 0 4.8e-03 2.3e-01 3.2e-01 1.3e-01
26 NAcc mRNA stability Syngap1 0.06 0.03 2.5e-04 0.02 0.02 0.02 0.02 2.6e-04 1.1e-04 1.5e-04 5.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.61.03.5-1.9-1.01.31.20.3-0.7-0.40.4-0.10.2-0.41.71.0-1.70.4-0.8-1.01.30.8-1.11.21.4-1.40.7-0.1-0.8
Area under the delay curve0.20.21.4-0.1-0.2-0.30.10.40.5-0.30.3-0.20.20.5-0.50.20.80.4-0.5-0.0-0.40.40.50.4-0.2-0.0-1.20.20.7
BMI with tail1.24.111.12.82.2-2.3-2.41.11.7-1.11.0-1.81.83.31.6-2.60.7-2.5-0.22.3-2.9-2.81.8-2.0-1.92.2-1.5-0.41.5
BMI without tail1.75.110.03.22.7-2.8-2.81.72.7-1.61.6-2.32.22.40.9-3.22.6-2.5-0.82.8-2.3-2.02.8-1.7-1.51.8-2.4-1.50.9
Body weight1.67.220.64.51.4-3.4-3.20.52.4-0.30.3-1.51.33.4-0.7-3.32.6-2.60.83.2-4.5-3.51.9-3.4-3.63.9-1.90.32.7
Weight adjusted by age1.11.77.81.41.1-1.5-1.10.10.40.1-0.10.3-0.40.9-1.2-1.30.90.10.61.2-1.8-1.8-0.0-1.7-2.62.8-0.11.52.2
Bone surface0.40.62.9-0.6-1.71.10.8-1.1-0.61.0-1.00.6-0.7-0.3-1.11.0-0.30.11.0-0.4-0.00.4-1.0-0.00.3-0.31.20.5-0.7
Bone volume0.10.21.1-0.8-1.00.70.6-0.2-0.20.1-0.1-0.00.10.10.00.7-0.5-0.1-0.0-0.30.20.4-0.60.40.5-0.70.60.0-0.5
Breakpoint value in progressive ratio session0.20.31.0-0.5-0.80.90.5-0.6-0.40.5-0.50.3-0.3-0.5-0.40.1-0.1-0.00.5-0.20.40.5-0.20.30.8-1.00.6-0.3-1.0
Number of licking bursts0.91.43.7-0.1-1.61.31.1-1.9-1.31.9-1.91.4-1.5-1.2-1.31.1-0.30.51.7-0.80.20.8-1.30.50.7-0.71.00.8-1.1
Context. condit. distance diff. score5.97.212.9-2.8-3.23.43.3-3.0-3.52.9-2.93.1-3.1-2.5-1.43.0-3.12.62.0-3.21.52.0-3.61.61.7-1.82.52.3-0.9
Locomotion velocity, session 11.31.44.2-1.8-1.21.11.3-0.5-1.10.5-0.51.1-1.1-2.0-0.81.4-0.61.8-0.1-0.91.61.9-0.21.51.3-1.20.10.1-0.5
Locomotion distance, session 10.60.72.9-1.7-0.21.00.9-0.1-0.7-0.00.00.2-0.2-0.60.91.7-1.30.4-0.4-0.51.21.3-0.11.01.2-1.10.2-0.3-0.9
Locomotion velocity, session 20.60.72.2-0.7-1.51.10.9-0.9-0.70.9-0.90.6-0.6-0.8-0.51.1-0.30.40.6-0.80.51.2-0.60.81.0-1.00.4-0.0-1.1
Locomotion distance, session 20.60.83.4-1.3-0.51.11.1-0.6-1.30.6-0.61.0-0.9-0.30.31.5-1.80.90.3-1.00.40.6-1.10.40.4-0.40.70.80.2
Locomotion velocity, session 30.50.62.0-0.20.4-0.1-0.30.81.0-0.80.8-1.11.10.10.80.40.9-0.8-0.90.40.40.80.90.60.8-0.6-0.7-1.4-0.9
Locomotion distance, session 31.01.14.1-2.0-0.41.11.0-0.1-0.7-0.00.00.2-0.2-0.90.81.5-1.10.7-0.5-1.11.51.6-0.61.51.6-1.70.5-0.4-1.1
Stereotopy head waving bouts, day 30.60.72.81.5-0.8-0.5-0.5-0.90.11.0-1.00.5-0.6-0.1-1.7-0.11.1-0.21.30.8-1.0-0.60.2-1.2-1.21.10.10.80.4
Stereotopy head waving duration, day 30.40.41.91.40.2-0.7-0.5-0.20.50.3-0.30.1-0.2-0.3-1.2-0.21.3-0.00.50.6-0.6-0.20.7-0.7-0.80.8-0.80.20.5
Locomotion velocity, session 72.32.610.7-2.9-1.11.71.9-0.6-2.20.6-0.61.4-1.3-0.90.92.4-3.32.0-0.2-2.11.51.1-1.91.31.1-1.21.21.20.4
Locomotion distance, session 72.73.412.7-3.6-0.82.12.4-0.2-2.00.1-0.11.3-1.1-1.71.12.4-2.92.4-0.8-2.32.61.9-1.32.22.0-2.10.90.7-0.4
Stereotopy head waving bouts, day 71.11.24.30.90.5-0.9-0.80.81.2-0.80.9-1.01.0-0.90.3-0.91.9-0.3-1.00.80.71.01.61.11.1-1.3-2.1-2.0-1.2
Stereotopy head waving duration, day 70.70.93.41.40.5-1.1-1.10.71.3-0.70.7-1.00.9-0.30.0-0.91.8-0.7-0.61.2-0.00.21.20.20.2-0.3-1.5-1.4-0.6
Locomotion velocity, session 83.33.98.6-1.3-2.92.22.1-2.8-2.32.8-2.82.6-2.7-2.0-2.72.3-0.91.82.3-1.50.21.7-1.80.60.6-0.61.41.6-0.6
Locomotion distance, session 84.97.214.5-3.1-2.83.23.1-3.0-3.72.9-2.93.2-3.2-1.9-1.03.5-3.72.42.1-3.11.11.6-3.81.11.2-1.43.02.4-0.5
Degree of sensitization distance0.70.71.6-0.3-1.10.60.7-1.1-1.11.1-1.11.2-1.2-0.6-1.10.2-0.60.81.1-0.40.0-0.3-0.8-0.4-0.50.40.91.30.3
Degree of sensitization stereotypy1.21.34.30.10.2-0.1-0.10.70.8-0.80.8-0.90.9-1.20.6-0.31.2-0.1-1.20.11.21.51.21.81.9-2.0-1.8-2.1-1.7
Conditioned locomotion0.80.92.41.3-1.1-0.1-0.4-1.1-0.21.1-1.20.4-0.40.9-1.4-0.70.1-0.71.50.1-1.5-1.2-0.7-1.3-1.11.00.51.00.3
Cocaine response after cond. corrected0.81.02.40.2-0.40.50.3-1.2-1.21.2-1.21.0-1.00.9-0.00.0-1.5-0.11.4-0.7-1.0-1.4-1.3-1.0-0.80.81.41.40.6
Cocaine response after cond. not corrected0.70.93.21.0-0.60.1-0.1-1.4-0.61.4-1.40.9-0.90.5-1.0-0.2-0.0-0.41.80.0-1.3-1.1-0.6-1.2-1.01.01.11.00.2
Cocaine response before conditioning1.11.39.81.7-0.2-1.0-1.1-0.01.60.0-0.0-0.70.6-0.2-1.8-0.33.1-1.00.41.9-0.90.41.7-0.8-0.70.6-0.8-1.0-0.5
Saline control response4.86.313.52.72.9-3.6-3.43.13.3-3.03.0-3.03.02.01.3-3.72.8-2.1-2.32.2-1.0-1.82.6-1.0-1.21.3-2.4-2.10.8
Bone: connectivity density0.61.04.0-1.5-1.41.41.3-0.5-1.20.5-0.50.6-0.6-0.30.81.2-2.00.60.3-0.90.60.1-1.80.30.5-0.61.21.0-0.2
Bone: cortical apparent density1.42.04.31.21.2-1.9-2.01.51.8-1.51.4-1.91.92.11.2-0.91.1-1.9-0.91.5-1.2-1.41.0-1.2-1.11.0-0.5-1.10.5
Bone: cortical area0.10.10.40.50.1-0.1-0.2-0.30.30.3-0.2-0.10.10.2-0.3-0.20.6-0.50.30.2-0.60.10.30.00.1-0.1-0.6-0.3-0.3
Bone: cortical porosity1.61.74.7-0.71.2-0.20.11.00.7-1.01.1-0.50.5-1.90.3-0.11.60.8-1.6-0.41.82.11.92.21.9-1.8-1.8-1.7-1.1
Bone: cortical porosity1.11.24.8-0.70.50.00.40.40.2-0.40.50.1-0.2-2.2-0.50.11.21.3-1.0-0.41.62.01.31.91.5-1.5-1.4-1.0-0.8
Bone: cortical thickness1.22.04.40.71.7-1.1-1.21.61.9-1.71.7-2.12.11.22.0-0.71.2-1.8-1.51.0-0.5-0.21.60.20.4-0.3-1.8-2.0-0.5
Bone: cortical thickness2.52.96.11.71.6-1.8-2.11.82.3-1.91.9-2.52.51.91.7-1.61.4-2.4-1.31.7-1.1-1.31.7-0.8-0.50.7-1.7-1.9-0.1
Bone: cortical tissue density1.31.84.01.21.1-1.8-1.91.41.8-1.41.3-1.71.72.01.0-0.91.1-1.8-0.81.5-1.2-1.40.9-1.2-1.11.1-0.4-0.90.5
Condit. Reinf. active minus inactive responses0.40.42.5-0.80.2-0.00.20.7-0.0-0.70.7-0.00.0-1.40.0-0.30.10.9-1.0-0.31.60.7-0.21.00.7-0.7-0.0-0.3-0.3
Condit. Reinf. active-inactive response ratio0.80.82.50.81.0-1.2-1.21.31.2-1.31.3-1.11.1-0.00.7-1.61.1-0.6-1.00.90.3-0.60.5-0.2-0.30.2-0.5-0.9-0.0
Condit. Reinf. active responses0.30.31.8-1.00.2-0.00.20.7-0.2-0.70.7-0.00.1-0.80.3-0.4-0.50.8-0.9-0.11.30.3-0.30.60.4-0.30.4-0.00.0
Condit. Reinf. inactive responses0.50.63.3-1.8-0.20.90.90.5-0.6-0.60.6-0.10.1-0.11.10.3-1.50.6-0.9-0.61.20.6-0.40.90.9-0.70.6-0.1-0.2
Incentive salience index mean1.31.73.3-1.6-1.21.41.6-1.0-1.61.0-1.01.5-1.4-1.7-0.90.9-1.41.70.4-1.61.41.0-1.81.21.1-1.01.21.0-0.4
Condit. Reinf. lever presses3.75.210.6-2.2-2.52.72.6-2.7-3.22.6-2.62.8-2.8-1.6-1.42.1-3.02.21.9-2.70.90.9-3.31.21.2-1.12.52.3-0.3
Condit. Reinf. active minus inactive responses0.10.21.50.10.7-0.3-0.10.20.6-0.10.2-0.20.1-0.1-0.6-0.01.2-0.1-0.10.7-0.20.40.6-0.2-0.30.50.1-0.20.2
Condit. Reinf. active-inactive response ratio0.20.31.20.40.5-0.4-0.2-0.30.20.4-0.40.5-0.5-0.4-1.1-0.21.10.40.50.6-0.40.10.3-0.5-0.70.80.20.40.5
Condit. Reinf. active responses0.10.10.5-0.40.5-0.00.00.30.5-0.30.4-0.30.3-0.2-0.20.30.7-0.0-0.30.50.20.50.40.20.10.10.3-0.4-0.2
Condit. Reinf. inactive responses0.30.31.00.00.3-0.3-0.40.70.8-0.80.8-1.01.00.60.6-0.00.4-0.8-0.70.5-0.0-0.00.50.10.2-0.2-0.4-0.9-0.4
Condit. Reinf. lever presses0.60.83.1-1.20.60.40.70.6-0.1-0.60.6-0.00.1-1.20.80.2-0.10.9-1.1-0.81.51.40.11.71.5-1.2-0.3-0.6-0.7
Condit. Reinf. lever reinforcers received0.10.20.6-0.60.50.10.10.30.4-0.30.3-0.20.2-0.5-0.20.30.80.1-0.40.50.50.70.50.40.4-0.10.3-0.6-0.4
Conditioned reinforcement - actives0.10.21.2-1.1-0.8-0.30.10.50.1-0.50.5-0.20.20.50.40.6-0.40.4-0.7-0.20.00.50.10.4-0.00.1-0.00.20.6
Conditioned reinforcement - inactives0.20.32.4-0.11.5-0.7-0.30.80.2-0.80.8-0.10.10.10.3-0.4-0.10.5-0.80.10.10.00.40.2-0.20.30.0-0.10.8
Conditioned locomotion0.30.41.4-1.0-0.7-0.20.50.1-0.5-0.00.00.5-0.5-0.2-0.10.3-0.71.2-0.3-0.70.20.2-0.70.4-0.30.70.71.11.1
Patch foraging indifference point 0 sec2.24.19.21.52.4-3.0-3.02.32.6-2.32.2-2.32.32.00.8-2.62.3-1.8-1.62.2-1.2-1.62.4-1.1-1.31.6-1.3-1.80.9
Patch foraging indifference point AUC0.20.31.80.2-0.70.0-0.3-0.10.60.0-0.0-0.30.3-0.6-0.70.21.3-0.50.20.50.30.30.7-0.00.2-0.10.3-0.7-0.9
Delay disc. indifference point, 0s delay0.40.40.9-0.5-0.70.30.6-0.7-0.70.8-0.80.9-0.90.3-0.90.7-0.50.90.6-0.2-0.50.1-0.60.1-0.30.3-0.20.90.8
Delay disc. indifference point, 16s delay0.50.51.60.11.0-0.6-0.21.20.9-1.11.1-0.90.90.70.7-0.20.6-0.0-1.3-0.10.20.30.70.50.1-0.4-1.3-0.30.3
Delay disc. indifference point, 2s delay0.30.42.2-0.4-0.7-0.10.5-0.3-0.10.5-0.40.7-0.7-0.3-1.50.50.71.00.3-0.0-0.30.7-0.10.1-0.60.50.20.70.9
Delay disc. indifference point, 24s delay0.80.83.30.41.8-1.4-0.71.31.1-1.21.2-0.60.60.2-0.2-0.91.30.4-1.20.70.1-0.11.20.2-0.60.3-1.4-0.20.9
Delay disc. indifference point, 4s delay0.50.52.80.7-0.9-0.6-0.50.21.1-0.20.2-0.60.51.0-0.8-0.11.7-0.5-0.00.8-1.10.20.8-0.4-0.60.4-0.8-0.50.3
Delay disc. indifference point, 8s delay0.20.22.0-0.30.5-0.30.20.50.2-0.40.4-0.10.10.1-0.2-0.10.30.7-0.6-0.1-0.10.20.50.5-0.0-0.1-1.40.30.8
Indifference point function ln k0.40.81.8-0.7-0.81.00.9-1.0-0.81.0-1.00.9-0.9-1.0-1.01.1-0.20.60.7-1.30.51.3-0.80.81.0-0.80.40.1-0.8
Indifference point function log k0.40.81.8-0.7-0.81.00.9-1.0-0.81.0-1.00.9-0.9-1.0-1.01.1-0.20.60.7-1.30.51.3-0.80.81.0-0.80.40.1-0.8
Patch foraging total patch changes 0 sec2.44.49.61.62.6-3.1-3.12.52.7-2.42.4-2.42.42.01.0-2.62.3-1.8-1.72.2-1.1-1.62.5-1.0-1.21.5-1.4-1.90.9
Patch foraging total patch changes 12 sec1.62.04.41.21.6-1.6-1.91.62.1-1.61.6-1.81.81.50.4-1.22.0-1.7-0.91.8-0.8-1.21.6-1.0-0.91.2-0.1-1.50.1
Patch foraging total patch changes 18 sec2.43.77.01.51.9-2.4-2.62.22.3-2.32.2-2.52.52.32.2-2.21.1-2.2-1.61.9-0.9-2.02.0-1.2-1.11.2-1.3-1.60.6
Patch foraging total patch changes 24 sec1.22.15.1-0.11.9-1.9-1.82.21.4-2.22.2-1.81.81.12.3-1.40.2-0.8-2.10.90.5-0.81.50.30.1-0.0-1.3-1.20.3
Patch foraging total patch changes 6 sec2.33.56.71.42.6-2.5-2.32.42.4-2.42.4-2.22.21.81.3-2.21.9-1.5-1.91.9-0.8-1.22.3-0.6-0.91.2-1.4-1.71.0
Patch foraging time to switch 0 sec0.61.34.91.31.3-0.7-0.70.30.1-0.30.3-0.40.42.21.4-1.3-1.1-1.00.10.7-1.6-2.2-0.3-1.4-1.51.4-0.30.91.3
Patch foraging water rate 0 sec0.10.21.20.50.5-0.7-0.50.30.4-0.20.2-0.10.10.2-0.3-0.10.6-0.10.00.4-0.4-0.40.4-0.8-1.01.10.1-0.00.9
Patch foraging water rate 12 sec0.20.51.8-0.50.2-0.3-0.50.80.6-0.80.8-0.91.00.01.20.50.1-0.6-0.9-0.20.50.40.50.40.7-0.5-0.7-1.3-0.5
Patch foraging water rate 18 sec0.30.51.70.70.2-1.3-1.20.70.8-0.60.6-0.80.81.10.5-0.60.6-0.6-0.50.7-0.6-0.60.5-0.7-0.60.6-1.0-0.40.6
Patch foraging water rate 24 sec0.20.31.2-0.4-0.1-0.3-0.50.50.8-0.60.5-0.80.80.70.50.80.5-0.8-0.40.5-0.10.20.4-0.4-0.1-0.10.3-1.1-0.2
Patch foraging water rate 6 sec0.10.20.70.10.2-0.4-0.60.30.6-0.40.4-0.70.70.70.60.50.4-0.9-0.20.2-0.2-0.10.4-0.3-0.00.30.2-0.7-0.1
Seeking ratio, delayed vs. immediate footshock1.51.98.30.9-0.8-0.9-1.60.52.1-0.60.6-1.81.71.00.1-0.32.9-2.4-0.01.8-0.90.12.1-0.60.3-0.1-0.6-2.2-1.8
Distance traveled before self-admin0.60.82.6-0.1-0.60.5-0.1-1.2-0.61.2-1.20.6-0.60.9-0.50.6-0.5-0.71.60.1-1.6-1.2-0.8-1.3-0.70.91.50.60.0
Distance traveled after self-admin0.81.03.01.5-0.8-1.0-1.5-0.51.00.4-0.4-0.60.50.9-0.7-0.51.7-1.71.01.1-1.6-0.70.5-1.5-0.80.90.0-0.6-0.5
Extensor digitorum longus weight0.31.22.3-0.6-1.51.01.1-1.4-1.21.5-1.51.4-1.40.1-0.91.5-0.90.91.2-1.1-0.50.2-1.50.1-0.10.11.31.50.5
Bone: elastic displacement0.91.03.2-0.61.7-0.7-0.41.60.9-1.51.6-0.90.9-0.21.5-0.30.60.3-1.8-0.10.90.61.10.90.6-0.5-0.8-1.10.2
Bone: elastic work0.20.31.20.01.1-0.7-0.50.80.6-0.70.7-0.50.50.30.6-0.60.6-0.1-0.80.2-0.20.00.80.2-0.0-0.0-0.8-0.60.5
Bone: endosteal estimation1.43.214.32.1-1.8-0.5-0.4-2.3-0.72.5-2.41.8-1.9-0.0-3.8-1.01.10.32.90.5-2.1-1.2-0.7-2.0-2.11.90.72.11.1
Bone: endosteal perimeter1.53.211.10.6-2.21.00.9-2.9-1.93.0-2.92.5-2.5-0.8-3.30.1-0.41.03.0-0.6-1.1-0.4-1.8-0.9-0.80.71.42.30.3
Epididymis fat weight4.716.234.43.15.6-4.2-4.64.64.3-4.64.5-5.15.15.95.3-4.31.2-4.7-3.44.0-2.8-3.94.1-2.4-2.02.2-3.0-3.01.6
Delta time in closed arm before/after self-admin0.40.41.90.41.4-0.6-0.3-0.3-0.20.4-0.40.4-0.40.6-0.5-0.6-0.1-0.00.50.4-1.1-1.00.1-0.3-0.71.10.30.31.0
Delta time in open arm before/after self-admin0.20.21.2-0.1-1.10.10.20.70.5-0.70.7-0.60.6-0.10.50.30.2-0.0-0.8-0.20.40.5-0.00.10.2-0.3-0.3-0.3-0.1
Diff in mean of infusions in LGA sessions1.11.44.0-1.6-1.01.81.5-1.1-1.61.0-1.11.2-1.1-0.70.10.9-2.00.80.8-1.50.80.5-1.80.20.5-1.01.31.1-0.5
Delay discount exponential model param0.20.21.40.10.10.4-0.1-0.5-0.60.4-0.40.3-0.2-0.40.5-0.2-1.0-0.40.60.00.4-0.6-0.6-0.50.10.11.20.0-0.6
Extinction: sum of active levers before priming0.70.82.1-0.5-0.11.10.9-1.2-1.21.2-1.21.3-1.3-0.8-1.00.5-0.70.71.1-0.6-0.20.2-1.1-0.10.1-0.01.40.8-0.1
Active lever presses in extinction session 60.60.63.4-0.71.8-0.20.41.0-0.1-0.90.9-0.10.1-0.10.7-1.3-0.80.8-1.20.10.7-0.20.40.7-0.0-0.1-0.70.21.1
Bone: final force1.93.16.12.41.6-2.4-2.51.01.7-0.90.9-1.41.42.50.6-2.21.2-2.0-0.11.9-2.4-2.41.3-2.2-2.12.0-1.0-0.51.4
Bone: final moment1.42.34.31.91.5-2.1-2.01.01.4-0.90.9-1.21.22.10.6-1.91.0-1.5-0.31.6-2.0-2.01.2-1.7-1.81.7-1.0-0.31.4
Food consumed during 24 hour testing period0.91.33.81.70.1-0.5-0.6-1.1-0.51.1-1.10.7-0.80.9-0.6-1.3-0.3-0.51.60.5-1.7-1.9-1.2-1.6-1.61.40.61.41.0
Glucose3.96.114.7-1.3-1.52.22.6-3.0-3.23.1-3.13.8-3.8-2.7-3.61.6-1.63.22.6-2.10.81.3-2.80.3-0.20.12.63.20.8
Heart weight0.60.93.31.01.8-1.7-1.10.61.0-0.40.5-0.20.10.1-1.1-0.61.80.2-0.30.9-0.7-0.11.6-0.5-1.11.2-0.90.21.3
Delay discount hyperbolic model param0.20.21.20.20.20.3-0.1-0.4-0.70.3-0.40.3-0.2-0.30.6-0.3-1.1-0.40.5-0.00.3-0.8-0.7-0.50.00.21.10.1-0.5
Intermittent access intake day 1-15 change0.10.31.31.2-0.3-0.2-0.60.10.6-0.20.2-0.50.5-0.0-0.2-0.30.9-0.7-0.00.6-0.1-0.10.5-0.10.3-0.2-1.0-0.9-0.8
Intermittent access intake escalation0.61.23.61.20.1-0.8-1.11.21.5-1.21.2-1.51.50.40.6-0.81.5-1.1-1.11.20.1-0.01.50.10.5-0.3-1.9-1.7-0.8
Intermittent access intake escalation 20.20.32.30.6-1.00.20.3-0.10.20.1-0.0-0.10.1-0.6-0.40.20.50.1-0.1-0.20.30.60.30.70.7-0.4-1.5-0.4-0.5
Intermitt. access day 1 inactive lever presses0.41.65.80.6-0.60.90.1-2.2-1.42.1-2.21.6-1.7-0.3-1.71.1-0.4-0.12.4-0.2-1.1-0.1-1.3-0.9-0.10.32.10.6-0.6
Intermitt. access day 15 inactive lever presses0.20.31.11.00.4-0.7-0.8-0.00.20.1-0.1-0.0-0.00.4-0.3-0.60.4-0.40.40.7-1.1-0.90.1-1.0-0.91.0-0.0-0.00.4
Intermitt. access escalation Index1.41.95.7-1.5-2.41.80.9-1.9-1.51.7-1.71.2-1.1-0.8-0.32.0-1.30.01.6-1.00.61.0-1.40.21.3-1.51.90.1-1.6
Intermittent access day 1 total infusions1.11.77.7-2.80.70.41.50.7-1.2-0.60.60.9-0.9-1.20.60.6-1.92.6-1.3-1.81.81.3-0.81.80.6-0.70.81.11.2
Intermittent access day 15 total infusions0.50.72.8-0.80.7-0.5-0.01.40.4-1.41.4-0.60.6-0.30.9-0.3-0.10.7-1.7-0.11.20.70.61.20.7-0.6-0.6-0.60.3
Intermittent access terminal intake (last 3 days)0.50.72.7-0.81.2-0.7-0.11.40.4-1.31.4-0.40.5-0.40.6-0.30.10.9-1.6-0.11.10.60.71.00.4-0.3-0.6-0.40.6
Intermittent access total infusions0.60.72.7-1.30.8-0.40.31.30.0-1.21.2-0.20.2-0.50.8-0.2-0.51.3-1.6-0.51.30.80.21.20.5-0.4-0.0-0.00.7
Intermittent access day 1 locomotion0.30.32.1-1.4-0.1-0.30.10.7-0.2-0.70.70.00.00.20.80.3-1.00.8-0.9-0.50.40.0-0.40.3-0.20.30.30.41.0
Intermittent access day 15 total locomotion0.40.72.20.70.1-1.4-1.00.70.8-0.60.6-0.60.61.10.1-0.90.6-0.4-0.40.7-1.0-1.00.4-0.7-1.31.5-0.50.31.2
Intermittent access total locomotion0.40.51.4-0.1-0.1-1.0-0.51.20.7-1.11.1-0.70.70.70.7-0.60.10.2-1.20.2-0.0-0.40.3-0.0-0.70.7-0.90.11.0
Intermittent access standard deviation1.32.86.42.52.0-2.1-2.31.61.9-1.51.5-1.61.61.80.4-2.11.7-1.6-0.82.1-1.5-1.81.5-1.5-1.41.7-1.4-1.20.8
Left kidney weight1.46.313.83.71.2-3.3-3.31.33.1-1.21.2-2.52.43.30.3-2.63.1-3.1-0.33.0-3.4-2.52.9-2.4-2.42.5-2.8-1.01.4
Right kidney weight1.35.915.03.90.6-3.0-3.10.82.7-0.70.7-2.02.03.40.1-2.42.5-3.00.32.9-3.8-2.92.3-2.9-2.93.0-2.0-0.41.8
Cocaine induced anxiety0.50.73.90.0-2.00.80.2-1.4-0.71.4-1.40.7-0.70.1-0.90.8-0.4-0.51.6-0.1-0.7-0.2-0.7-0.8-0.10.00.80.4-0.7
Post-drug Anxiety0.30.31.10.6-1.0-0.0-0.4-0.8-0.00.7-0.80.1-0.10.7-0.5-0.40.3-0.81.10.8-1.0-0.60.0-0.9-0.40.10.20.1-0.5
Baseline Anxiety0.30.31.50.71.2-0.7-0.50.60.5-0.50.5-0.30.30.50.1-1.00.5-0.0-0.40.7-0.4-0.50.4-0.3-0.60.5-0.60.00.6
Tail length0.51.911.12.5-0.6-1.4-1.2-0.71.20.9-0.90.2-0.3-0.3-2.7-0.93.3-0.51.31.6-1.7-0.41.1-1.4-1.51.7-0.8-0.10.5
Length with tail0.83.610.93.2-0.9-1.9-1.5-1.01.11.3-1.20.4-0.60.8-3.3-1.32.9-0.61.91.8-3.0-1.70.5-2.6-2.93.1-0.71.12.0
Length without tail1.65.117.73.2-0.4-1.8-1.6-1.20.31.5-1.50.6-0.72.6-2.2-1.30.8-1.02.31.5-4.2-3.0-0.4-3.5-3.94.00.02.33.2
Times rat made contact with spout1.71.95.6-0.41.1-0.6-0.52.01.3-2.12.1-1.71.8-0.12.0-0.40.7-0.3-2.4-0.01.30.81.31.41.2-1.4-1.5-2.0-0.7
Lifetime Intake0.50.62.3-1.41.0-0.50.21.20.0-1.11.2-0.10.1-0.30.7-0.4-0.41.3-1.5-0.41.10.50.21.00.2-0.10.30.11.0
Liver weight, left1.22.06.51.6-2.0-0.4-0.6-2.0-0.72.1-2.11.3-1.40.4-2.1-0.30.5-0.22.50.3-1.7-1.2-0.8-1.7-1.61.61.11.60.5
Liver weight, right1.42.510.20.6-2.5-0.0-0.2-2.2-1.22.4-2.31.9-2.0-0.1-3.20.60.20.82.5-0.1-1.4-0.4-1.3-1.3-1.21.31.41.90.8
Locomotor activity0.61.05.51.5-0.5-1.4-2.0-0.41.10.4-0.4-0.60.5-0.0-0.9-0.12.3-1.50.80.9-0.8-0.00.6-0.7-0.1-0.0-0.4-1.4-1.4
Locomotor testing distance0.30.62.21.1-0.4-0.9-1.5-0.80.40.7-0.7-0.10.10.2-0.90.11.3-1.21.10.5-0.9-0.5-0.0-0.9-0.20.30.3-0.6-1.0
Locomotor testing rearing0.50.93.31.0-0.7-0.9-1.4-0.90.20.8-0.90.2-0.20.7-1.20.00.8-1.01.41.0-1.6-1.1-0.2-1.8-1.31.20.80.10.1
Locomotion in novel chamber0.10.10.40.1-0.5-0.1-0.00.10.4-0.10.1-0.40.40.5-0.00.60.2-0.4-0.2-0.6-0.10.4-0.10.20.3-0.20.0-0.1-0.1
Locomotion in novel chamber post-restriction0.61.02.41.00.8-1.2-1.20.71.1-0.60.6-0.90.81.50.3-0.90.8-1.0-0.21.0-1.1-1.40.9-1.2-1.21.6-0.5-0.31.0
Fecal boli incidents, locomotor time 10.30.42.4-0.8-0.40.00.4-0.0-0.90.1-0.10.6-0.6-0.30.30.1-1.51.1-0.2-0.70.4-0.0-1.00.50.0-0.10.11.00.8
Change in fecal boli incidents, locomotor task1.11.13.11.6-0.1-0.2-0.4-1.1-0.11.1-1.10.7-0.70.2-1.8-0.61.0-0.51.71.1-1.2-1.0-0.2-1.6-1.41.31.60.60.1
Time >=10cm from walls, locomotor time 12.22.47.22.2-0.6-0.2-0.8-1.6-0.11.6-1.70.6-0.71.6-1.7-1.30.5-1.32.41.0-2.7-2.5-0.6-2.4-2.02.01.41.00.7
Bouts of movement, locomotor time 10.50.52.2-0.4-1.51.00.5-0.4-0.10.3-0.3-0.10.1-0.50.20.50.0-0.30.2-0.50.61.0-0.30.81.4-1.40.0-0.7-1.5
Total resting periods, locomotor time 10.40.42.3-0.4-1.51.00.6-0.5-0.30.4-0.40.1-0.1-0.70.00.4-0.1-0.00.3-0.50.60.8-0.50.51.1-1.20.2-0.3-1.2
Rest time, locomotor task time 10.60.83.4-1.1-1.80.90.9-0.7-0.50.7-0.70.6-0.6-1.0-0.51.6-0.20.70.2-0.60.31.30.11.21.3-1.00.0-0.1-0.5
Distance moved, locomotor task time 10.91.34.11.61.6-1.5-1.40.70.8-0.60.6-0.60.61.00.0-1.80.8-0.8-0.01.3-0.8-1.80.4-1.8-2.01.6-0.10.10.8
Vertical activity count, locomotor time 11.22.98.82.42.0-2.2-2.11.21.4-1.21.1-1.21.21.90.5-3.01.1-1.5-0.32.0-1.3-2.50.8-2.2-2.52.2-0.7-0.11.2
Time >=10cm from walls, locomotor time 21.42.17.42.01.4-1.6-1.2-0.30.20.5-0.50.6-0.60.9-1.7-1.80.8-0.01.11.4-1.8-2.20.2-2.1-2.72.50.11.62.0
Bouts of movement, locomotor time 20.20.41.60.3-1.3-0.0-0.4-0.00.6-0.10.1-0.50.5-0.1-0.30.21.2-0.5-0.10.20.10.60.60.40.9-0.7-0.3-1.2-1.2
Total resting periods, locomotor time 20.40.62.8-0.4-1.70.60.2-0.40.30.3-0.3-0.10.1-0.7-0.70.71.2-0.10.2-0.20.51.20.30.81.3-1.00.1-1.1-1.6
Rest time, locomotor task time 21.72.28.6-0.7-2.91.81.2-2.3-1.62.3-2.31.6-1.6-0.6-1.51.9-1.00.42.1-1.1-0.40.5-1.60.20.7-0.61.40.9-0.8
Distance moved, locomotor task time 22.53.010.11.83.2-2.3-1.51.91.1-1.71.7-1.01.01.50.8-2.80.3-0.2-1.31.5-0.8-2.51.1-1.4-2.42.4-1.30.72.4
Vertical activity count, locomotor time 21.72.36.21.62.5-2.1-1.31.50.9-1.31.3-0.70.71.40.5-2.30.4-0.1-0.91.5-0.9-2.10.9-1.4-2.42.3-1.10.82.3
Light reinforcement 10.71.76.52.10.3-0.7-1.4-0.40.50.4-0.4-0.40.42.0-0.1-0.70.2-2.01.30.8-2.0-2.4-0.7-2.6-1.92.01.00.20.4
Light reinforcement 20.71.13.41.5-0.1-0.4-0.6-0.7-0.20.7-0.80.4-0.41.4-0.3-0.4-0.4-0.71.20.4-1.8-1.8-0.8-1.8-1.71.80.70.71.1
Bone: marrow area1.53.214.22.3-1.7-0.7-0.6-2.2-0.62.4-2.41.7-1.80.2-3.8-1.11.20.22.80.7-2.3-1.4-0.6-2.1-2.22.00.62.11.2
Bone: maximum diameter1.22.36.4-0.3-2.11.31.4-2.2-1.72.3-2.32.1-2.1-1.3-2.51.2-0.61.32.0-1.2-0.10.8-1.50.30.3-0.21.01.7-0.2
Bone: maximum force0.61.13.21.30.7-1.4-1.30.40.9-0.30.3-0.70.71.7-0.0-1.00.7-1.10.11.2-1.8-1.40.8-1.5-1.51.4-0.6-0.01.2
Bone: maximum moment0.40.71.90.90.7-1.0-0.90.40.7-0.30.3-0.40.41.3-0.0-0.70.5-0.6-0.00.9-1.4-1.00.7-1.1-1.31.2-0.50.21.2
Mean time between licks in bursts1.74.39.2-1.8-3.02.32.2-2.7-2.22.6-2.62.4-2.4-2.1-2.32.8-0.91.62.2-1.70.81.8-2.51.01.2-1.12.01.5-1.2
Mean num. licks in bursts1.82.87.7-0.12.0-1.6-1.32.81.9-2.82.8-2.22.31.12.2-1.00.8-0.8-2.70.70.4-0.22.00.2-0.0-0.1-1.8-1.90.5
Cd content in liver1.01.15.5-0.21.1-0.5-0.10.5-0.7-0.40.40.4-0.41.00.7-0.4-1.90.7-0.20.3-0.4-1.5-0.9-1.2-1.71.80.71.72.4
Co content in liver1.82.15.22.01.6-1.7-1.51.11.0-1.01.0-1.00.91.70.5-2.20.4-1.0-0.41.9-1.4-2.31.2-1.6-2.01.9-1.10.31.7
Cu content in liver1.01.23.9-1.11.3-0.0-0.11.50.9-1.61.6-1.41.40.22.0-0.00.1-0.6-1.70.31.10.61.20.91.0-0.9-0.7-1.4-0.9
Fe content in liver0.50.61.90.60.9-0.7-0.71.00.8-0.90.9-1.01.01.41.1-0.60.2-0.7-0.80.7-0.8-0.70.9-0.6-0.60.7-0.5-0.30.8
K content in liver0.90.92.6-1.2-1.01.61.6-0.8-1.00.8-0.80.7-0.7-0.70.11.5-1.20.60.3-1.10.61.1-0.70.91.1-1.20.30.5-0.7
Mg content in liver2.62.66.2-1.1-2.51.91.5-2.4-2.02.3-2.31.9-1.9-1.5-1.61.8-1.30.92.0-1.40.50.9-1.60.61.1-1.01.61.1-1.2
Mn content in liver3.84.29.1-1.1-2.62.12.0-2.9-2.53.0-3.02.7-2.7-0.9-3.02.3-1.61.52.7-1.8-0.40.5-2.3-0.3-0.20.12.12.50.2
Na content in liver0.60.62.3-0.30.30.3-0.10.50.8-0.60.6-1.01.00.11.20.20.8-0.9-0.70.00.40.80.80.71.1-1.2-0.4-1.5-1.4
Rb content in liver0.40.41.8-0.4-0.90.30.3-0.5-1.00.6-0.60.8-0.80.1-0.20.1-1.30.80.5-0.40.0-0.6-0.9-0.2-0.20.30.91.20.7
Se content in liver1.92.35.3-1.3-1.61.51.4-2.0-1.51.9-1.91.9-1.9-2.1-2.32.0-0.11.41.6-1.10.91.6-0.90.81.1-1.21.50.6-1.2
Sr content in liver0.50.42.00.10.3-0.30.1-0.4-0.80.5-0.50.9-0.90.0-0.5-0.1-0.81.00.4-0.3-0.3-0.3-0.5-0.1-0.80.70.21.31.4
Zn content in liver0.80.92.8-0.6-0.41.01.2-0.9-1.10.9-0.91.2-1.2-0.4-1.31.2-1.01.00.9-0.1-0.1-0.1-1.0-0.5-0.90.81.01.71.0
Bone: minimum diameter1.01.85.60.6-1.40.50.5-2.1-1.32.2-2.21.8-1.9-0.5-2.4-0.2-0.20.62.3-0.1-1.2-0.4-1.1-0.9-0.90.70.61.80.5
Time in familiar zone, hab. session 12.01.96.4-1.40.50.20.41.90.7-2.02.0-1.31.4-0.32.30.2-0.50.4-2.5-0.82.01.30.61.91.8-1.7-1.3-1.3-0.6
Time in novel zone, hab. session 11.31.33.91.4-0.4-0.5-0.6-1.4-0.21.4-1.40.9-0.90.2-2.00.20.9-0.51.91.1-1.7-0.9-0.1-1.7-1.61.70.80.80.6
Total zone transitions, hab. session 10.40.52.5-1.0-0.30.90.6-0.7-0.60.6-0.60.4-0.4-0.70.31.6-0.5-0.10.5-0.40.71.1-0.20.61.0-0.90.5-0.4-1.3
Total locomotion distance, hab. session 10.60.83.4-1.4-0.41.51.2-0.9-0.90.8-0.80.6-0.5-0.40.31.8-1.00.10.6-0.70.61.2-0.40.71.1-0.90.7-0.0-1.2
Locomotion velocity, hab. session 10.40.62.6-1.2-0.11.31.0-0.7-0.60.6-0.60.4-0.4-0.40.31.6-0.60.00.4-0.50.61.1-0.10.71.0-0.90.5-0.2-1.2
Time in familiar zone, hab. session 20.80.83.30.4-0.5-0.2-0.70.61.3-0.80.7-1.51.50.71.30.31.0-1.8-0.40.7-0.10.00.8-0.20.4-0.4-0.5-1.5-1.5
Time in novel zone, hab. session 20.40.42.80.40.8-0.7-0.10.4-0.2-0.30.30.5-0.5-0.3-0.7-0.8-0.21.3-0.40.00.0-0.30.1-0.1-0.70.7-0.20.81.7
Total zone transitions, hab. session 20.30.41.5-0.5-0.80.50.0-0.9-0.30.8-0.80.1-0.10.70.31.2-0.5-1.01.00.1-0.50.2-0.4-0.40.1-0.10.90.1-1.0
Total locomotion distance, hab. session 20.91.14.2-1.4-1.11.51.0-1.3-1.11.1-1.20.6-0.50.30.52.0-1.5-0.41.0-1.30.10.7-1.40.20.8-0.91.40.3-1.3
Locomotion velocity, hab. session 21.31.75.6-1.8-1.21.81.3-1.5-1.41.4-1.40.9-0.9-0.10.32.4-1.7-0.11.2-1.60.41.0-1.60.51.1-1.11.60.4-1.4
Novel to familiar place preference ratio0.20.20.7-0.20.8-0.10.10.4-0.2-0.40.40.2-0.2-0.5-0.0-0.3-0.10.7-0.5-0.80.80.4-0.40.50.3-0.30.50.00.2
Novelty place preference0.10.20.6-0.10.7-0.20.00.4-0.0-0.30.40.1-0.1-0.6-0.2-0.30.20.7-0.5-0.70.70.4-0.20.50.3-0.20.4-0.10.1
Time in novel zone, NPP test0.10.10.5-0.00.5-0.3-0.10.40.1-0.40.40.1-0.1-0.6-0.3-0.30.40.7-0.5-0.60.70.5-0.10.50.2-0.20.3-0.20.1
Total zone transitions, NPP test1.11.64.5-2.1-0.81.81.6-1.1-1.71.0-1.01.2-1.2-0.80.22.1-2.01.00.6-1.20.91.3-1.10.91.1-1.11.10.7-0.7
Total locomotion distance, NPP test1.01.47.1-2.0-0.31.51.5-0.8-1.80.8-0.81.2-1.2-0.20.71.6-2.71.10.4-1.40.60.5-1.40.60.5-0.61.01.20.3
Locomotion velocity, NPP test1.31.89.2-2.2-0.11.81.8-1.0-2.11.0-1.01.4-1.3-0.30.81.6-3.01.10.5-1.70.70.5-1.60.80.9-0.91.21.3-0.0
Intraocular pressure0.20.31.6-0.9-0.4-0.0-0.00.80.2-0.90.8-0.60.60.81.30.0-0.70.0-0.90.40.4-0.30.1-0.2-0.2-0.00.30.10.4
Delta distance traveled before/after self-admin1.21.35.61.50.3-1.7-1.41.01.6-1.01.0-1.21.1-0.0-0.3-1.42.4-0.7-0.81.30.20.41.4-0.1-0.40.1-1.6-1.0-0.3
Delta ambulatory time before/after self-admin0.81.05.31.5-0.4-1.4-1.40.61.4-0.60.6-0.90.9-0.1-0.7-1.22.3-0.8-0.31.20.10.31.2-0.5-0.50.2-1.3-0.9-0.4
Parametrial fat weight1.33.19.32.50.5-2.0-2.30.91.5-0.90.8-1.71.73.01.8-1.70.2-2.4-0.21.8-2.5-2.70.7-2.2-1.92.0-1.2-0.31.3
Pavlov. Cond. lever latency5.36.611.53.12.1-3.1-3.32.23.1-2.22.2-2.92.93.41.7-2.82.1-3.2-1.03.3-2.4-3.02.3-2.9-2.72.4-1.8-1.21.2
Pavlov. Cond. magazine entry latency2.22.87.3-1.9-1.92.02.1-1.2-1.31.1-1.11.3-1.3-2.6-1.11.7-0.21.80.3-1.92.02.7-0.72.32.3-2.30.7-0.0-1.7
Pavlov. Cond. change in total contacts0.80.93.3-1.0-0.80.80.9-0.7-0.80.7-0.60.9-0.9-1.8-1.20.40.11.20.2-0.81.31.4-0.11.31.2-1.10.4-0.0-0.9
Pavlov. Cond. index score4.05.19.4-2.6-2.12.82.9-2.0-2.42.0-1.92.4-2.4-3.1-1.62.3-1.42.70.9-2.92.22.9-1.72.72.6-2.41.20.9-1.3
Pavlov. Cond. latency score4.35.49.9-2.7-2.12.83.0-2.1-2.52.1-2.02.5-2.5-3.1-1.72.3-1.42.71.0-3.02.22.9-1.82.82.7-2.51.30.8-1.4
Pavlov. Cond. lever contacts4.65.59.5-2.7-1.82.83.0-2.4-3.12.4-2.43.0-3.0-2.7-1.72.4-2.33.01.4-2.81.72.2-2.42.11.9-1.71.91.6-0.5
Pavlov. Cond. magazine entry number1.72.15.21.61.5-1.8-1.91.01.2-1.00.9-1.21.22.21.0-1.50.3-1.5-0.31.9-1.8-2.30.7-2.0-2.01.9-0.7-0.11.4
Pavlov. Cond. intertrial magazine entries1.11.33.70.41.9-1.4-1.31.60.7-1.61.6-1.01.11.41.4-1.1-0.5-0.5-1.21.5-0.2-1.50.6-0.8-1.11.1-0.3-0.21.3
Pavlov. Cond. lever-magazine prob. diff.4.04.99.1-2.6-2.02.72.9-1.9-2.41.8-1.82.4-2.3-3.0-1.52.3-1.52.70.8-2.82.22.9-1.72.72.5-2.41.20.9-1.2
Pavlov. Cond. response bias3.03.76.5-2.2-1.92.42.6-1.7-2.01.7-1.72.0-2.0-2.5-1.32.3-1.22.20.8-2.41.82.5-1.42.12.1-2.01.40.8-1.2
Pavlov. Cond. lever latency0.71.03.10.6-1.10.2-0.0-1.3-0.71.4-1.41.0-1.00.4-1.6-0.0-0.3-0.21.80.4-1.1-1.0-0.6-1.5-1.30.91.01.20.4
Pavlov. Cond. magazine entry latency0.30.41.8-0.4-0.40.50.8-0.2-0.80.3-0.30.8-0.8-0.9-0.2-0.2-0.71.3-0.1-1.00.70.4-0.70.90.5-0.4-0.10.70.4
Pavlov. Cond. change in total contacts0.40.71.8-0.31.0-0.3-0.11.10.7-1.11.1-0.80.8-0.70.7-0.60.80.2-1.4-0.01.00.80.61.31.1-0.8-1.0-1.2-0.5
Pavlov. Cond. index score0.30.41.9-0.60.30.30.50.60.0-0.50.6-0.10.1-0.80.5-0.10.00.8-1.0-0.81.00.9-0.01.41.1-0.7-0.5-0.4-0.1
Pavlov. Cond. latency score0.30.41.5-0.50.30.20.50.60.2-0.60.6-0.30.3-0.60.5-0.10.20.6-1.0-0.70.80.80.21.21.0-0.6-0.6-0.4-0.1
Pavlov. Cond. lever contacts0.60.82.5-0.31.2-0.3-0.11.20.7-1.21.3-0.91.0-0.21.5-0.20.30.1-1.6-0.30.90.80.71.31.2-0.8-1.0-1.1-0.3
Pavlov. Cond. magazine entry number0.10.10.50.1-0.1-0.1-0.4-0.10.30.0-0.1-0.30.20.3-0.20.60.5-0.70.30.6-0.30.10.4-0.5-0.30.10.2-0.3-0.4
Pavlov. Cond. intertrial magazine entries0.81.14.1-0.8-2.01.40.9-1.4-0.71.3-1.30.7-0.7-1.1-1.61.40.2-0.11.3-0.20.61.1-0.50.20.7-0.81.3-0.0-1.8
Pavlov. Cond. lever-magazine prob. diff.0.30.41.7-0.50.40.20.50.60.1-0.50.6-0.20.2-0.70.6-0.20.00.8-1.0-0.70.90.8-0.01.31.0-0.7-0.5-0.4-0.1
Pavlov. Cond. response bias0.40.62.6-0.70.40.30.50.6-0.0-0.60.6-0.20.2-0.81.10.1-0.20.8-1.1-0.91.11.10.01.61.4-1.0-0.7-0.5-0.3
Time in closed arm before self-admin0.10.10.60.4-0.70.00.2-0.4-0.20.4-0.40.4-0.4-0.4-0.70.30.20.40.3-0.2-0.10.5-0.1-0.1-0.20.1-0.30.60.2
Time in closed arm after self-admin0.10.10.5-0.60.7-0.20.2-0.2-0.30.2-0.20.4-0.40.1-0.30.2-0.30.50.1-0.3-0.40.10.10.5-0.00.10.20.40.7
Time in open arm before self-admin0.50.62.7-0.90.80.30.50.1-0.4-0.20.20.3-0.3-1.3-0.00.10.00.9-0.5-0.61.70.8-0.01.51.3-1.1-0.0-0.6-0.8
Time in open arm after self-admin0.30.31.3-0.2-0.80.40.40.40.2-0.40.4-0.20.2-0.90.10.30.40.4-0.6-0.41.21.1-0.00.80.8-0.8-0.5-0.6-0.6
Bone: periosteal estimation0.71.46.31.8-1.0-0.6-0.6-1.5-0.01.6-1.50.8-0.90.3-2.5-0.71.3-0.31.90.6-1.8-0.8-0.1-1.3-1.31.2-0.01.00.5
Bone: periosteal perimeter0.40.73.50.9-0.60.10.1-1.4-0.51.4-1.41.0-1.0-0.5-1.9-0.60.60.21.4-0.2-0.8-0.1-0.4-0.2-0.20.2-0.10.6-0.0
Bone: post-yield work1.21.74.40.1-1.90.60.7-1.9-1.62.0-2.01.8-1.9-0.5-2.10.7-0.91.01.9-0.1-0.8-0.3-1.4-0.7-0.70.70.91.80.7
Progressive ratio test 1 active lever presses0.30.41.9-0.91.0-0.30.40.5-0.6-0.40.40.6-0.6-0.20.0-0.4-0.81.4-0.6-0.50.3-0.2-0.60.2-0.60.40.50.81.3
Progressive ratio test 1 breakpoint0.30.41.9-0.81.0-0.30.40.4-0.6-0.30.40.6-0.6-0.2-0.0-0.4-0.81.4-0.6-0.60.3-0.2-0.60.2-0.60.50.50.91.3
Progressive ratio test 1 inactive lever presses0.20.30.90.30.9-0.5-0.50.50.1-0.50.5-0.30.30.90.8-0.4-0.7-0.3-0.40.4-0.7-0.7-0.2-0.7-0.80.30.20.20.6
Progressive ratio test 2 active lever presses0.30.31.0-1.00.10.30.70.4-0.3-0.40.40.1-0.0-0.30.50.3-0.80.8-0.8-0.80.70.7-0.21.00.6-0.60.00.30.1
Progressive ratio test 2 breakpoint0.30.41.3-1.00.20.30.70.6-0.2-0.60.6-0.00.1-0.40.70.3-0.70.8-0.9-0.70.90.8-0.01.10.7-0.8-0.20.10.1
Progressive ratio test 2 inactive lever presses0.60.93.2-0.8-0.10.51.1-0.5-1.40.6-0.61.4-1.4-1.0-0.70.6-1.31.80.2-1.30.60.5-1.40.5-0.1-0.20.91.40.8
Incentive Sensitization - Responses0.40.62.3-0.8-1.10.90.8-0.3-0.30.2-0.20.1-0.1-0.70.21.2-0.30.2-0.1-0.90.91.40.01.21.5-1.3-0.1-0.3-1.1
Incentive Sensitization - Breakpoint0.50.62.5-0.8-1.00.90.7-0.2-0.30.1-0.1-0.00.1-0.60.41.1-0.30.1-0.2-0.80.91.30.11.21.6-1.3-0.2-0.4-1.1
Sum of active levers in priming session hrs 5-60.30.20.9-0.70.30.20.4-0.2-0.50.2-0.20.6-0.6-1.0-0.5-0.1-0.10.9-0.0-0.70.90.3-0.30.70.4-0.50.30.2-0.1
Progressive ratio3.35.110.72.81.8-2.5-2.91.43.0-1.41.4-2.62.52.60.3-2.13.0-3.2-0.43.3-2.6-2.12.9-2.1-1.71.8-1.9-1.80.3
Food seeking constrained by brief footshock0.60.84.00.22.0-0.7-0.11.20.6-1.11.2-0.70.70.20.6-1.30.30.3-1.30.00.5-0.10.91.00.4-0.1-1.7-0.50.4
Seeking ratio, punishment vs. effort1.92.77.2-1.9-0.21.52.1-0.7-2.10.7-0.71.8-1.8-2.3-0.41.1-1.82.7-0.1-2.52.41.8-1.82.21.7-1.50.91.0-0.3
Retroperitoneal fat weight0.10.41.80.50.6-0.2-0.20.20.0-0.20.2-0.30.31.30.9-0.6-0.8-0.5-0.00.5-1.0-1.2-0.1-0.8-0.70.8-0.10.41.0
Reaction time number correct0.91.83.11.51.4-1.6-1.61.51.6-1.51.5-1.71.71.30.8-1.41.1-1.5-1.01.8-0.4-1.01.5-0.9-0.60.8-1.6-1.40.3
Reaction time mean minus median1.02.56.3-1.8-2.51.82.0-1.6-2.01.6-1.61.9-1.9-2.2-0.81.1-1.61.91.0-1.71.21.2-1.80.90.8-1.21.31.5-0.5
Reaction time mean minus median AUC1.23.18.3-2.4-1.91.82.3-1.3-2.51.3-1.32.3-2.2-2.5-0.91.2-2.32.90.6-1.91.71.0-2.11.00.6-1.11.22.10.4
Reaction time num false alarms0.30.41.6-0.3-0.90.70.3-1.0-0.20.9-0.90.4-0.4-0.3-1.10.60.7-0.41.00.3-0.20.60.00.10.6-0.60.8-0.4-1.3
Reaction time num false alarms AUC0.40.62.7-0.1-0.90.70.2-1.10.11.0-1.00.2-0.3-0.3-1.20.61.2-0.71.10.5-0.30.80.40.10.7-0.70.6-0.7-1.6
Reaction time trials correct on left0.91.83.11.51.4-1.6-1.61.51.6-1.51.5-1.71.71.30.8-1.41.1-1.5-1.01.8-0.4-1.01.5-0.9-0.60.8-1.6-1.40.3
Reaction time trials on left0.91.73.11.51.4-1.5-1.61.41.6-1.41.4-1.61.61.30.8-1.41.1-1.5-1.01.8-0.4-1.01.5-0.9-0.70.8-1.6-1.30.3
Reaction time mean2.03.27.2-1.3-2.11.41.8-2.0-2.72.1-2.12.6-2.6-1.9-1.30.7-2.42.41.5-1.70.50.4-2.30.40.1-0.21.32.60.7
Reaction time mean AUC1.72.86.6-1.4-2.01.31.7-1.8-2.61.9-1.92.5-2.5-1.8-1.20.6-2.32.41.3-1.50.50.3-2.10.50.1-0.31.02.40.8
Median of all reaction times1.62.25.7-0.9-1.51.01.3-1.7-2.31.8-1.82.3-2.3-1.3-1.10.4-2.22.01.4-1.30.1-0.0-2.10.1-0.20.21.12.41.0
Reaction time omissions1.31.95.6-1.2-2.41.61.5-1.9-1.91.8-1.81.8-1.8-1.1-1.20.8-1.51.11.6-1.10.40.4-1.7-0.10.1-0.61.31.5-0.4
Reaction time false alarm rate1.11.53.2-1.0-1.51.51.1-1.8-0.91.7-1.71.2-1.3-1.3-1.61.40.50.41.6-0.60.21.4-0.60.71.1-1.11.60.2-1.6
Reaction time premature initiation rate0.10.20.70.70.4-0.4-0.40.10.00.0-0.00.1-0.10.2-0.2-0.1-0.1-0.00.1-0.3-0.5-0.5-0.8-0.5-0.70.80.10.50.8
Reaction time premature initiations0.61.02.61.61.2-1.4-1.40.91.1-0.90.9-1.01.01.20.1-1.10.8-1.0-0.50.8-0.9-1.20.3-1.1-1.21.3-0.9-0.30.9
Std. dev. reaction times1.52.96.2-1.6-2.41.82.1-1.8-2.21.9-1.82.3-2.3-2.5-1.50.8-1.32.31.3-1.51.11.2-1.70.80.6-1.01.11.8-0.3
Reaction time trials completed0.91.73.11.51.4-1.5-1.61.41.6-1.41.4-1.61.61.30.8-1.41.1-1.5-1.01.8-0.4-1.01.5-0.9-0.70.8-1.6-1.30.3
Reaction time trials AUC0.91.63.11.51.3-1.5-1.61.31.5-1.41.3-1.61.51.30.8-1.41.0-1.5-0.91.8-0.5-1.11.4-1.0-0.80.8-1.6-1.20.4
Run reversals in cocaine runway, females0.60.62.6-0.11.6-1.0-0.31.10.3-1.11.1-0.50.50.81.1-0.8-0.50.3-1.10.1-0.1-0.60.50.3-0.50.4-0.60.41.2
Run reversals in cocaine runway, males0.90.93.7-0.8-1.91.21.1-1.0-1.01.0-1.01.0-1.0-0.7-0.61.1-0.71.00.6-1.40.60.8-1.10.80.8-0.70.20.5-0.5
Latency to leave start box in cocaine runway1.11.22.9-0.30.11.11.2-1.5-1.71.5-1.51.7-1.7-1.1-1.00.3-1.41.11.3-1.30.20.3-1.30.30.4-0.11.01.40.1
Latency to leave start box in cocaine runway, F0.70.82.2-0.8-0.20.70.8-1.0-1.51.1-1.11.4-1.4-0.8-0.60.6-1.31.10.9-0.90.30.2-1.00.30.30.01.01.10.2
Latency to leave start box in cocaine runway, M0.40.40.80.70.60.60.6-0.9-0.60.9-0.90.7-0.7-0.3-0.8-0.5-0.30.10.9-0.8-0.4-0.1-0.80.10.20.10.40.70.1
Std. dev. time between licks in bursts3.24.49.7-1.2-2.92.22.0-3.1-2.13.1-3.12.6-2.6-1.8-2.62.9-0.51.42.7-1.40.01.7-2.20.60.8-0.52.11.9-0.9
Total sessions with >9 infusions0.40.51.7-1.31.0-0.7-0.21.20.3-1.11.1-0.30.3-0.10.4-0.40.30.9-1.30.10.70.20.40.60.0-0.00.6-0.40.6
Short access day 1 total inactive lever presses0.60.83.6-1.00.5-0.00.7-0.4-1.30.5-0.51.4-1.4-1.1-0.60.2-0.91.90.2-1.10.70.5-1.20.4-0.3-0.01.11.11.1
Short access day 10 total inactive lever presses0.30.83.40.7-0.80.9-0.4-1.4-0.61.3-1.30.4-0.40.1-0.30.6-0.2-1.31.60.1-0.5-0.4-0.5-1.00.6-0.81.2-0.8-1.8
Short access day 1 total infusions0.50.73.1-1.41.2-0.10.50.5-0.7-0.40.40.8-0.8-0.9-0.1-0.2-0.71.8-0.7-0.81.20.4-0.80.6-0.1-0.01.50.71.0
Short access day 10 total infusions0.30.42.2-1.50.9-0.4-0.21.1-0.0-1.01.0-0.20.2-0.00.8-0.2-0.50.8-1.20.10.8-0.00.40.60.4-0.20.4-0.50.5
Short access total infusions0.50.73.2-1.81.3-0.40.31.0-0.4-0.90.90.4-0.3-0.40.4-0.4-0.71.6-1.2-0.41.00.3-0.20.7-0.00.00.90.31.1
Short access day 1 locomotion0.50.75.4-1.50.10.80.5-0.6-1.00.6-0.60.8-0.8-0.5-0.20.7-0.90.60.5-0.70.60.0-1.20.10.5-0.52.30.3-0.6
Short access day 10 total locomotion0.71.33.51.2-0.7-0.4-1.0-1.10.51.1-1.10.3-0.40.9-1.80.11.7-1.01.70.8-1.9-1.0-0.4-1.7-1.21.71.20.1-0.1
Short access total locomotion0.40.52.7-0.2-0.1-0.1-0.3-0.6-0.40.6-0.60.8-0.80.2-0.90.10.10.30.90.1-0.7-0.9-0.9-1.1-1.01.21.60.60.5
One hour access (0.3 mA shock)1.31.54.3-1.6-1.91.61.4-0.7-0.90.6-0.60.5-0.4-0.70.32.1-1.10.50.1-1.71.31.6-0.91.41.8-1.61.20.1-1.3
Compulsive drug intake3.33.910.9-0.0-3.32.31.5-3.3-2.03.1-3.21.9-1.9-0.5-1.72.1-1.3-0.33.2-1.6-0.80.2-2.4-0.50.5-0.82.41.5-1.6
One hour access (shock baseline)0.91.45.7-1.30.9-0.50.21.90.7-1.91.9-1.01.0-0.11.5-0.3-0.10.9-2.4-0.41.60.91.01.70.9-0.4-1.0-0.70.7
Social response proportion0.40.52.00.60.0-0.2-0.3-0.7-0.10.7-0.70.6-0.60.5-1.4-0.40.6-0.11.00.4-1.1-0.5-0.3-0.9-1.00.90.80.20.6
Social responses0.40.51.80.5-0.3-0.4-0.9-0.50.50.5-0.5-0.10.00.5-1.10.01.3-0.90.91.0-1.0-0.30.1-1.0-0.50.20.8-0.6-0.5
Social time2.73.613.2-0.8-3.62.41.4-3.2-1.63.0-3.01.7-1.8-0.7-1.91.9-0.3-0.43.1-1.0-0.60.6-1.7-0.40.7-0.72.80.5-2.2
Soleus weight2.36.720.6-0.1-2.81.61.6-3.8-2.54.0-4.03.5-3.6-1.0-4.52.1-0.61.64.1-1.1-1.6-0.0-2.5-1.4-1.41.33.03.40.9
Bone: stiffness0.60.93.01.10.4-1.0-1.20.40.9-0.50.4-0.90.91.70.2-0.70.5-1.50.11.1-1.4-1.30.6-1.4-1.21.1-0.4-0.30.5
Tibialis anterior weight0.20.52.90.10.4-0.2-0.30.81.0-0.80.8-1.21.21.71.30.30.4-1.1-0.60.3-0.7-0.40.3-0.20.0-0.10.1-0.6-0.2
Time to tail flick, vehicle, before self-admin0.80.86.4-0.1-2.50.9-0.1-1.00.10.8-0.8-0.40.40.90.51.0-0.1-1.71.10.3-1.0-0.3-0.0-0.90.3-0.5-0.1-0.5-1.5
Time to tail flick, vehicle, after self-admin0.20.30.9-1.0-0.90.50.5-0.5-0.70.5-0.50.7-0.7-0.7-0.30.1-0.30.70.3-0.60.60.4-0.60.20.3-0.40.80.4-0.2
Time to tail flick, test, before self-admin0.80.82.90.1-0.50.2-0.30.41.0-0.50.5-1.11.20.20.70.71.0-1.2-0.50.40.40.61.30.61.3-1.1-1.0-1.6-1.7
Time to tail flick, test, after self-admin1.61.76.5-1.4-1.31.21.10.0-0.5-0.10.20.00.0-1.40.71.1-0.70.8-0.8-1.32.02.00.32.42.5-2.5-1.0-0.8-1.6
Delta time to tail flick, vehicle, before/after SA1.21.24.3-1.31.8-0.10.81.1-0.6-1.01.00.5-0.4-1.30.5-0.9-1.02.1-1.6-0.92.10.7-0.11.80.8-0.60.00.30.9
Delta time to tail flick, test, before/after SA0.30.32.0-0.70.10.40.6-0.1-0.90.1-0.10.5-0.5-0.30.5-0.2-1.40.7-0.2-0.80.50.3-0.60.70.5-0.6-0.20.50.2
Tibia length0.92.510.22.3-1.9-0.6-1.2-2.0-0.02.1-2.10.8-1.00.7-3.2-0.41.5-1.02.70.9-2.3-1.3-0.3-2.0-1.61.51.00.90.1
Ambulatory time before self-admin0.20.31.5-0.7-0.10.60.2-0.7-0.50.6-0.70.4-0.40.4-0.00.6-0.6-0.30.7-0.2-0.7-0.5-0.5-0.30.10.11.20.2-0.2
Ambulatory time after self-admin0.50.62.31.0-0.7-0.8-1.2-0.30.80.3-0.3-0.50.40.5-0.7-0.51.5-1.20.70.9-1.1-0.20.4-1.0-0.50.50.2-0.6-0.5
Bone: tissue strength0.30.32.1-0.10.4-0.6-0.30.3-0.1-0.20.20.2-0.20.50.1-0.4-0.40.5-0.20.1-0.4-0.7-0.1-0.5-0.90.80.20.61.5
Total heroin consumption0.20.21.2-0.0-0.70.6-0.0-0.6-0.00.5-0.50.0-0.0-0.1-0.40.20.4-0.70.70.6-0.00.30.3-0.30.4-0.50.3-0.5-1.1
Bone: trabecular number0.81.24.7-2.0-0.61.41.30.5-0.7-0.60.6-0.20.3-0.42.21.1-1.90.4-1.0-1.01.60.8-1.11.21.4-1.30.7-0.3-0.8
Bone: trabecular spacing1.21.65.32.31.2-1.9-1.7-0.00.90.2-0.2-0.1-0.00.6-1.5-1.82.0-0.50.61.5-1.7-1.11.0-1.4-1.71.4-1.10.11.1
Bone: trabecular thickness0.50.63.0-1.1-1.10.90.80.2-0.6-0.30.3-0.20.20.21.10.7-1.70.3-0.7-1.00.70.3-0.80.91.0-0.90.10.3-0.2
Bone: trabecular tissue density0.20.41.10.00.4-0.3-0.10.50.4-0.50.5-0.20.2-0.9-0.6-0.11.00.5-0.7-0.31.00.90.90.90.7-0.6-0.4-0.6-0.4
Water consumed over 24 hours0.20.20.70.2-0.70.30.2-0.8-0.50.8-0.80.6-0.6-0.3-0.70.3-0.10.20.8-0.3-0.20.1-0.6-0.1-0.1-0.10.60.6-0.1
Number of responses in last shaping day1.01.14.7-0.40.90.21.1-1.0-0.71.1-1.11.5-1.5-1.3-2.20.50.51.51.0-0.8-0.20.7-0.70.5-0.50.71.31.60.7