Hub : Genes

Strada

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC mRNA stability Strada 0.06 0.04 3.0e-03 0.06 0.05 0.03 0.06 1.2e-03 3.1e-03 2.7e-02 1.4e-03
2 BLA mRNA stability Strada 0.09 0.04 2.5e-06 0.09 0.09 0.1 0.09 1.7e-05 1.6e-05 8.5e-06 1.7e-05
3 IL mRNA stability Strada 0.34 0.11 3.2e-07 0.32 0.22 0.28 0.09 1.4e-08 4.2e-06 2.3e-07 3.7e-03
4 BLA gene expression Strada 0.32 0.13 0.0e+00 0.28 0.31 0.33 0.32 5.5e-15 5.5e-17 5.6e-18 3.2e-17
5 Liver mRNA stability Strada 0.03 0.02 6.0e-03 0 0.01 0.01 0 3.5e-01 2.8e-02 3.9e-02 1.7e-01
6 NAcc gene expression Strada 0.18 0.06 0.0e+00 0.24 0.27 0.26 0.27 1.2e-36 6.9e-41 4.6e-40 1.9e-40
7 IC gene expression Strada 0.3 0.1 4.4e-16 0.32 0.3 0.32 0.33 4.0e-14 6.1e-13 2.8e-14 2.0e-14
8 NAcc mRNA stability Strada 0.07 0.03 0.0e+00 0.12 0.13 0.13 0.13 2.6e-18 2.0e-19 1.6e-18 1.1e-18
9 LHb mRNA stability Strada 0.15 0.09 6.8e-03 0.03 0.04 0 0.03 5.3e-02 4.2e-02 2.7e-01 6.1e-02
10 PL gene expression Strada 0.2 0.06 0.0e+00 0.29 0.31 0.32 0.31 7.3e-32 2.2e-34 5.1e-35 1.5e-34
11 PL isoform ratio NM_001415111.1 0.03 0.03 8.7e-03 0 0.01 0.01 0.01 9.9e-02 4.4e-02 6.9e-02 3.7e-02
12 pVTA mRNA stability Strada 0.04 0.02 3.6e-04 0.04 0.03 0.04 0.04 1.9e-04 8.6e-04 5.9e-04 5.5e-04
13 IL gene expression Strada 0.21 0.11 5.1e-04 0.14 0.1 0.09 0.15 3.1e-04 2.7e-03 4.6e-03 1.9e-04
14 PL mRNA stability Strada 0.2 0.08 0.0e+00 0.26 0.27 0.26 0.28 1.3e-28 1.3e-29 3.5e-28 1.2e-30
15 Brain mRNA stability Strada 0.24 0.08 0.0e+00 0.34 0.34 0.32 0.34 3.6e-32 3.1e-32 1.5e-30 6.7e-33
16 Adipose mRNA stability Strada 0.2 0.07 0.0e+00 0.25 0.27 0.27 0.27 5.0e-28 4.5e-30 2.5e-30 5.4e-30
17 pVTA gene expression Strada 0.13 0.06 1.4e-12 0.17 0.14 0.15 0.16 2.6e-13 1.3e-11 3.3e-12 6.1e-13
18 OFC mRNA stability Strada 0.59 0.13 1.6e-09 0.24 0.36 0.32 0.34 1.9e-06 2.7e-09 2.0e-08 7.3e-09
19 NAcc intron excision ratio chr10_91604053_91614708 0.01 0.01 8.4e-03 0 0 -0 0 1.1e-01 7.3e-02 9.9e-01 3.7e-01
20 Brain gene expression Strada 0.14 0.06 4.6e-15 0.16 0.15 0.15 0.15 9.7e-15 3.3e-14 1.6e-13 9.9e-14
21 Brain isoform ratio NM_001415111.1 0.07 0.05 7.4e-04 0.01 0.02 0.02 0.03 3.4e-02 3.1e-03 7.7e-03 1.5e-03
22 NAcc intron excision ratio chr10_91604053_91611075 0.03 0.02 3.3e-04 0.03 0.03 0.04 0.03 1.0e-05 3.8e-05 2.5e-06 9.9e-06
23 Adipose intron excision ratio chr10_91604053_91617313 0.04 0.02 1.5e-03 0.01 0.02 0.02 0.01 1.0e-02 6.1e-03 1.1e-03 1.8e-02
24 NAcc intron excision ratio chr10_91611103_91614708 0.02 0.01 7.6e-04 0.01 0.01 0.01 0.01 1.9e-02 3.9e-03 3.4e-03 3.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.61.03.71.61.11.90.31.81.21.10.81.21.40.40.60.81.10.71.20.7-0.50.10.90.7-0.2-0.50.1
Area under the delay curve0.10.20.80.60.20.90.00.50.20.50.10.50.40.20.30.30.40.40.40.40.10.30.10.5-0.0-0.8-0.5
BMI with tail1.24.211.92.01.41.43.30.71.51.92.01.61.61.12.22.22.12.21.12.43.4-1.52.31.71.9-3.41.3
BMI without tail2.98.818.83.52.42.74.32.02.53.02.92.72.92.13.23.33.03.02.03.24.3-1.93.02.12.5-4.31.7
Body weight3.414.725.44.73.83.95.03.13.74.14.03.83.73.13.84.14.13.93.23.84.8-3.33.93.92.7-4.32.1
Weight adjusted by age0.40.61.3-1.1-1.0-0.7-1.0-1.0-1.0-0.8-0.8-0.8-0.8-0.7-0.8-0.8-0.9-0.7-0.6-0.8-0.40.5-0.8-0.1-0.60.7-0.3
Bone surface3.66.513.63.63.13.71.73.53.02.92.62.82.72.62.32.42.62.32.81.91.5-2.22.23.00.9-0.51.0
Bone volume2.95.211.93.22.73.51.53.22.62.62.32.62.62.12.12.22.52.12.51.81.1-1.62.12.50.7-0.91.1
Breakpoint value in progressive ratio session0.20.21.2-0.40.50.10.10.30.40.10.40.20.40.60.10.10.40.30.40.30.2-0.80.6-0.31.10.20.7
Number of licking bursts0.00.10.6-0.50.1-0.1-0.7-0.0-0.1-0.1-0.1-0.1-0.20.20.2-0.30.00.10.10.3-0.2-0.3-0.00.2-0.10.70.0
Context. condit. distance diff. score0.10.10.9-0.6-0.2-0.90.3-0.7-0.4-0.3-0.2-0.4-0.3-0.10.2-0.3-0.4-0.1-0.20.00.2-0.2-0.1-0.90.1-0.0-0.2
Locomotion velocity, session 10.70.82.51.61.11.01.01.31.10.90.81.01.20.80.91.00.80.50.80.60.4-0.50.40.7-0.0-0.60.1
Locomotion distance, session 10.10.10.80.90.10.30.40.50.10.2-0.10.30.40.00.10.3-0.1-0.10.0-0.1-0.00.5-0.4-0.1-0.5-0.2-0.4
Locomotion velocity, session 20.40.41.40.40.90.30.71.00.90.60.70.60.71.20.40.60.40.20.9-0.00.0-1.10.2-0.10.80.60.9
Locomotion distance, session 20.10.10.90.10.1-0.40.10.20.0-0.1-0.2-0.00.10.4-0.20.0-0.3-0.20.2-0.3-0.4-0.1-0.6-1.0-0.20.8-0.3
Locomotion velocity, session 30.40.41.1-0.7-0.3-0.3-0.4-0.5-0.6-0.7-0.6-0.6-0.5-0.6-0.7-0.8-0.5-0.5-0.6-1.1-0.70.5-0.7-1.0-1.00.7-0.7
Locomotion distance, session 30.10.10.9-0.10.30.2-0.20.20.0-0.1-0.1-0.1-0.20.1-0.4-0.20.0-0.00.2-0.6-0.4-0.2-0.20.1-0.61.0-0.4
Stereotopy head waving bouts, day 30.40.51.4-0.6-0.8-0.1-0.7-0.3-0.6-0.6-0.7-0.5-0.3-1.0-0.3-0.6-0.4-0.7-0.6-0.7-1.21.2-0.6-0.6-0.9-0.2-0.7
Stereotopy head waving duration, day 30.40.41.0-1.0-0.8-0.5-0.8-0.5-0.7-0.6-0.7-0.5-0.3-0.7-0.1-0.6-0.4-0.6-0.5-0.6-1.01.0-0.5-0.9-0.5-0.0-0.4
Locomotion velocity, session 70.50.51.1-0.9-0.7-0.3-0.4-0.6-0.6-0.8-0.7-0.7-0.5-0.9-0.6-0.7-0.7-0.7-0.8-1.1-0.80.8-0.8-0.7-0.90.2-0.9
Locomotion distance, session 70.10.10.5-0.5-0.3-0.10.1-0.1-0.3-0.1-0.2-0.00.00.1-0.20.1-0.4-0.2-0.1-0.70.30.3-0.4-0.40.2-0.00.2
Stereotopy head waving bouts, day 70.70.82.1-0.7-0.6-0.7-1.0-0.5-0.7-0.9-0.9-0.8-0.8-0.7-0.8-1.0-0.8-1.1-0.7-1.1-1.40.7-0.9-1.3-1.01.2-0.9
Stereotopy head waving duration, day 71.92.35.8-1.5-1.1-1.7-1.9-1.0-1.3-1.6-1.5-1.4-1.4-1.1-1.3-1.7-1.3-1.7-1.0-1.6-2.41.1-1.4-2.1-1.31.9-1.2
Locomotion velocity, session 80.40.52.00.40.9-0.60.60.20.70.60.80.40.30.90.80.50.80.60.80.90.6-1.40.70.60.4-0.10.1
Locomotion distance, session 80.10.21.3-0.20.3-0.70.70.10.10.10.00.10.30.50.40.1-0.00.30.50.2-0.1-0.50.1-1.10.50.10.3
Degree of sensitization distance0.20.21.00.30.0-0.10.60.20.20.40.30.50.50.60.60.70.10.20.30.30.9-0.10.30.00.9-1.00.6
Degree of sensitization stereotypy1.21.33.2-0.9-0.7-1.3-1.0-0.8-0.9-1.2-1.1-1.1-1.2-0.7-1.2-1.3-1.2-1.3-1.0-1.2-1.30.7-1.2-1.8-1.11.7-1.1
Conditioned locomotion0.80.93.20.30.60.61.20.80.70.90.81.01.10.90.80.90.81.01.00.40.7-0.61.1-0.21.8-1.21.7
Cocaine response after cond. corrected0.40.51.3-0.5-0.6-0.1-1.0-0.7-0.7-0.5-0.6-0.7-0.8-0.6-0.7-0.6-0.7-0.7-0.9-0.7-0.10.4-1.01.1-1.11.0-0.7
Cocaine response after cond. not corrected0.91.03.9-0.6-0.40.0-1.3-0.6-0.8-0.8-0.8-0.9-1.0-0.6-1.0-1.0-0.9-1.0-1.0-1.1-0.60.3-1.30.9-1.62.0-1.2
Cocaine response before conditioning0.20.21.4-0.20.30.2-0.50.20.0-0.4-0.2-0.3-0.3-0.1-0.4-0.6-0.3-0.3-0.0-0.4-1.00.0-0.4-0.6-0.81.2-0.7
Saline control response2.53.48.50.71.40.82.51.21.61.71.91.61.61.92.11.81.81.91.72.12.0-1.92.10.42.9-1.92.4
Bone: connectivity density1.21.85.31.91.62.20.72.31.61.61.31.71.81.21.11.21.41.21.71.10.1-0.61.21.00.3-0.50.4
Bone: cortical apparent density3.95.310.8-2.0-2.5-1.6-2.1-2.1-2.5-2.5-2.6-2.2-1.7-2.9-2.4-2.3-2.2-2.1-2.3-2.5-2.73.3-2.1-2.8-2.10.7-1.7
Bone: cortical area0.61.04.31.61.12.11.11.21.01.00.91.01.10.40.80.91.10.90.50.00.8-0.40.71.5-0.2-0.40.6
Bone: cortical porosity5.35.814.92.53.03.22.12.52.82.42.92.12.02.62.02.22.42.01.91.22.6-3.31.83.91.2-0.01.8
Bone: cortical porosity4.14.411.52.42.63.01.92.12.42.22.51.91.82.21.81.92.21.81.70.92.4-2.71.83.40.9-0.21.4
Bone: cortical thickness5.69.216.8-2.1-3.2-1.5-2.5-2.7-3.1-3.1-3.1-3.1-2.6-4.1-3.4-3.1-2.7-3.1-3.7-3.9-2.94.0-3.1-2.0-3.81.5-2.6
Bone: cortical thickness3.84.56.9-1.7-2.2-1.1-1.9-1.8-2.1-2.2-2.1-2.2-1.9-2.6-2.6-2.2-2.1-2.2-2.4-2.6-2.12.6-2.1-1.8-2.31.5-1.9
Bone: cortical tissue density3.75.110.4-2.0-2.5-1.6-2.0-2.0-2.4-2.5-2.5-2.1-1.7-2.9-2.3-2.3-2.2-2.1-2.3-2.5-2.73.2-2.1-2.8-2.00.7-1.6
Condit. Reinf. active minus inactive responses3.03.44.31.42.01.91.92.02.02.02.01.92.02.12.01.91.81.82.01.61.8-1.91.81.11.9-1.01.8
Condit. Reinf. active-inactive response ratio1.11.21.90.71.31.21.11.21.21.21.21.11.21.41.21.11.01.11.30.81.0-1.31.10.51.2-0.40.9
Condit. Reinf. active responses4.04.96.31.82.32.22.32.42.32.32.32.42.42.42.52.32.42.32.52.01.8-2.22.31.22.4-1.52.3
Condit. Reinf. inactive responses1.31.62.51.31.31.21.11.51.31.31.21.51.61.21.51.31.51.41.51.30.7-0.81.40.71.1-1.11.1
Incentive salience index mean2.43.04.61.72.11.91.82.12.01.81.91.91.81.91.61.71.81.72.01.31.2-1.81.81.11.6-0.71.4
Condit. Reinf. lever presses0.40.61.41.01.20.60.91.21.10.70.80.80.70.80.30.71.00.61.0-0.2-0.2-0.80.80.20.50.00.5
Condit. Reinf. active minus inactive responses5.47.012.42.73.23.22.33.52.92.92.63.03.03.32.52.72.62.53.22.51.8-2.62.51.42.0-0.92.0
Condit. Reinf. active-inactive response ratio3.13.66.81.92.32.41.42.62.22.12.02.12.02.31.91.82.01.72.32.01.1-2.01.71.41.3-0.51.3
Condit. Reinf. active responses6.99.714.22.93.53.53.13.83.33.43.13.43.53.73.03.23.03.13.63.02.5-2.93.01.72.8-1.82.7
Condit. Reinf. inactive responses2.73.45.61.41.71.92.21.91.71.91.72.02.22.01.82.01.72.01.91.51.7-1.31.90.42.4-1.82.3
Condit. Reinf. lever presses2.12.94.11.82.01.72.02.01.91.81.81.81.82.01.51.81.71.61.91.61.4-1.81.60.71.6-0.91.5
Condit. Reinf. lever reinforcers received6.18.512.62.83.33.42.93.53.13.22.93.23.33.42.83.02.92.93.32.92.3-2.72.81.72.6-1.82.6
Conditioned reinforcement - actives0.61.02.11.21.01.11.30.70.91.01.01.01.00.91.21.01.01.20.91.01.5-0.90.70.70.5-0.80.2
Conditioned reinforcement - inactives0.91.42.81.51.31.51.50.91.21.11.31.01.20.81.21.01.11.30.81.41.7-1.00.91.20.4-1.2-0.3
Conditioned locomotion3.24.26.72.52.22.62.12.02.22.22.32.12.21.92.22.12.12.32.02.22.5-1.91.81.71.0-1.30.6
Patch foraging indifference point 0 sec4.07.410.52.62.72.83.13.02.63.02.53.03.12.63.02.82.72.92.73.22.3-1.92.91.32.7-2.62.6
Patch foraging indifference point AUC0.71.01.61.31.10.81.20.91.01.01.01.11.00.90.81.10.91.21.11.20.9-1.01.10.50.8-1.00.5
Delay disc. indifference point, 0s delay0.30.41.1-0.8-0.8-0.3-1.0-0.3-0.7-0.5-0.7-0.4-0.4-0.6-0.5-0.7-0.4-0.3-0.3-0.6-1.00.9-0.3-0.5-0.1-0.1-0.8
Delay disc. indifference point, 16s delay0.70.81.70.90.51.30.60.80.61.00.81.00.90.70.90.90.90.90.91.11.0-0.40.61.10.7-1.30.5
Delay disc. indifference point, 2s delay0.50.51.81.10.71.10.01.30.60.80.31.00.90.60.60.50.80.71.00.4-0.60.10.50.5-0.3-0.5-0.6
Delay disc. indifference point, 24s delay1.82.04.11.91.11.51.41.31.31.51.41.51.51.21.51.61.41.41.31.61.6-0.81.21.20.9-2.00.5
Delay disc. indifference point, 4s delay0.60.71.4-0.7-0.7-0.1-0.9-0.6-0.8-0.6-0.8-0.8-0.9-0.7-1.0-0.9-0.8-0.8-0.8-1.0-0.80.8-1.20.1-1.21.0-1.1
Delay disc. indifference point, 8s delay0.10.10.90.2-0.20.5-0.40.2-0.20.0-0.30.10.2-0.4-0.20.0-0.2-0.1-0.2-0.0-0.50.9-0.1-0.0-0.3-0.8-0.7
Indifference point function ln k0.20.31.0-0.8-0.6-0.1-0.5-0.3-0.6-0.6-0.7-0.5-0.3-0.6-0.5-0.6-0.3-0.6-0.7-0.6-0.91.0-0.5-0.7-0.40.30.1
Indifference point function log k0.20.31.0-0.8-0.6-0.1-0.5-0.3-0.6-0.6-0.7-0.5-0.3-0.6-0.5-0.6-0.3-0.6-0.7-0.6-0.91.0-0.5-0.7-0.40.30.1
Patch foraging total patch changes 0 sec4.27.910.72.72.82.93.13.02.73.12.63.03.12.73.12.92.73.02.73.32.5-2.02.91.62.7-2.62.6
Patch foraging total patch changes 12 sec5.67.29.92.82.72.12.82.92.82.92.63.02.83.02.72.92.62.83.13.02.0-2.52.91.32.9-2.22.5
Patch foraging total patch changes 18 sec2.84.35.72.02.11.82.42.02.12.22.12.12.12.12.22.31.92.21.82.42.4-2.02.21.22.3-1.72.0
Patch foraging total patch changes 24 sec2.84.87.12.52.42.52.32.72.32.52.12.52.62.12.22.42.12.32.22.51.8-1.52.30.91.6-1.81.4
Patch foraging total patch changes 6 sec2.63.95.61.92.12.12.42.12.02.11.92.12.11.92.02.01.92.11.92.21.7-1.62.01.41.8-1.71.8
Patch foraging time to switch 0 sec0.30.61.5-0.9-0.9-0.9-1.0-0.8-0.6-0.8-0.6-0.8-1.0-0.5-0.9-0.7-0.6-1.0-0.7-1.2-0.50.3-0.90.2-0.30.90.2
Patch foraging water rate 0 sec1.63.35.12.21.82.12.21.81.82.01.81.92.11.41.82.01.72.01.52.21.9-1.01.91.21.3-2.30.8
Patch foraging water rate 12 sec0.81.64.5-0.8-1.1-0.5-1.2-1.2-1.3-1.2-1.3-1.3-1.3-1.4-1.2-1.3-1.2-1.3-1.5-1.3-0.61.4-1.4-0.4-2.11.0-1.9
Patch foraging water rate 18 sec0.20.31.50.10.00.4-0.70.4-0.2-0.1-0.4-0.10.1-0.1-0.2-0.3-0.3-0.3-0.1-0.2-0.80.6-0.3-0.9-1.10.6-1.2
Patch foraging water rate 24 sec0.10.10.7-0.1-0.0-0.0-0.6-0.1-0.3-0.1-0.3-0.2-0.30.1-0.1-0.3-0.3-0.2-0.1-0.3-0.10.1-0.4-0.1-0.80.8-0.7
Patch foraging water rate 6 sec0.10.20.90.40.20.9-0.30.40.00.1-0.10.10.4-0.30.2-0.00.10.3-0.20.4-0.10.70.0-0.1-0.8-0.2-0.8
Seeking ratio, delayed vs. immediate footshock0.10.10.50.1-0.2-0.50.5-0.4-0.10.00.2-0.1-0.1-0.00.20.3-0.1-0.0-0.10.10.7-0.20.50.10.4-0.6-0.5
Distance traveled before self-admin0.60.83.3-1.3-0.6-0.4-1.4-0.8-0.9-0.9-0.8-0.9-1.0-0.6-1.0-1.0-0.8-0.8-0.8-0.7-0.60.3-0.90.3-1.11.8-0.4
Distance traveled after self-admin0.20.21.5-0.70.1-0.1-0.7-0.3-0.3-0.3-0.3-0.4-0.60.3-0.4-0.6-0.6-0.2-0.1-0.4-0.1-0.6-0.4-0.1-0.11.2-0.3
Extensor digitorum longus weight0.93.612.4-2.6-3.0-3.5-1.0-3.4-2.4-1.8-1.6-2.0-2.1-2.5-0.9-1.5-1.3-1.3-2.3-0.90.01.7-0.80.00.1-1.8-0.7
Bone: elastic displacement2.52.85.5-1.0-1.5-1.1-1.7-1.5-1.5-1.7-1.6-1.7-1.7-2.0-2.1-1.8-1.6-1.9-1.8-1.9-1.61.7-1.8-0.9-2.31.3-2.0
Bone: elastic work0.30.41.70.6-0.10.6-0.3-0.1-0.1-0.3-0.1-0.3-0.1-1.0-0.9-0.3-0.1-0.4-0.7-1.0-0.30.7-0.40.6-1.3-0.1-1.0
Bone: endosteal estimation14.832.543.05.86.56.05.46.16.26.06.15.95.66.66.05.95.55.75.95.65.6-6.35.35.44.9-2.74.6
Bone: endosteal perimeter15.833.743.66.16.55.85.66.06.26.36.26.05.56.66.06.05.85.86.15.75.8-6.65.66.14.7-2.84.4
Epididymis fat weight0.41.52.81.30.91.01.40.91.01.21.21.21.21.01.51.51.21.20.91.31.6-0.81.11.21.1-1.71.0
Delta time in closed arm before/after self-admin0.40.31.0-0.1-0.3-0.1-0.6-0.3-0.4-0.6-0.5-0.5-0.5-0.5-0.7-0.6-0.7-0.7-0.6-0.8-0.70.5-0.7-0.0-1.00.7-0.8
Delta time in open arm before/after self-admin0.30.31.3-0.3-0.2-0.20.0-0.1-0.00.10.10.30.6-0.00.70.30.40.60.30.60.20.10.4-0.91.1-1.00.9
Diff in mean of infusions in LGA sessions1.62.04.1-1.7-1.6-2.0-1.0-1.7-1.5-1.6-1.4-1.5-1.3-1.5-1.5-1.5-1.3-1.5-1.5-1.1-1.31.3-1.3-1.7-0.40.3-1.1
Delay discount exponential model param0.20.30.9-0.8-0.3-1.0-0.2-0.7-0.4-0.6-0.3-0.6-0.5-0.3-0.4-0.5-0.5-0.5-0.5-0.5-0.2-0.1-0.2-0.7-0.00.80.4
Extinction: sum of active levers before priming0.20.21.3-0.30.10.10.30.10.10.20.20.30.40.30.80.10.30.50.50.30.2-0.30.5-0.61.2-0.60.9
Active lever presses in extinction session 61.91.93.10.91.31.31.81.21.41.41.51.31.31.31.61.31.41.31.21.61.5-1.41.61.21.5-1.01.6
Bone: final force0.30.43.01.20.81.70.30.90.60.50.40.50.50.20.10.30.40.40.3-0.20.2-0.10.11.2-0.90.4-0.3
Bone: final moment0.30.43.31.10.81.80.30.90.60.50.40.50.50.20.10.30.40.40.2-0.30.1-0.10.11.2-1.00.5-0.4
Food consumed during 24 hour testing period3.04.26.62.22.11.42.61.62.02.02.12.02.11.92.32.22.22.31.72.02.3-1.92.31.52.0-2.41.7
Glucose1.32.03.4-1.6-1.4-1.6-1.2-1.8-1.6-1.5-1.4-1.6-1.8-1.3-1.4-1.5-1.4-1.6-1.6-1.7-0.80.8-1.6-0.5-1.41.4-1.0
Heart weight0.30.41.70.2-0.60.2-0.4-0.7-0.7-0.4-0.6-0.5-0.6-0.8-0.6-0.5-0.5-0.5-0.9-0.80.30.8-0.50.2-1.30.1-0.9
Delay discount hyperbolic model param0.20.30.9-0.8-0.4-1.0-0.2-0.7-0.4-0.6-0.3-0.6-0.5-0.3-0.4-0.4-0.5-0.5-0.5-0.5-0.1-0.1-0.2-0.70.00.80.5
Intermittent access intake day 1-15 change0.10.11.0-0.20.0-0.40.5-0.5-0.0-0.00.2-0.2-0.5-0.00.0-0.1-0.00.1-0.3-0.10.6-0.60.11.00.10.3-0.0
Intermittent access intake escalation0.20.42.10.30.50.11.0-0.10.40.50.70.2-0.00.50.50.40.50.50.10.41.1-1.10.61.50.5-0.10.3
Intermittent access intake escalation 20.40.52.60.50.60.30.90.10.60.60.80.40.20.60.60.50.60.70.20.41.2-1.20.71.60.7-0.20.5
Intermitt. access day 1 inactive lever presses1.24.56.62.12.32.22.62.32.32.22.32.22.31.92.42.22.22.22.12.31.8-1.82.21.71.9-1.71.6
Intermitt. access day 15 inactive lever presses1.42.94.91.41.42.11.91.51.71.71.81.61.91.01.81.81.71.81.12.21.9-0.82.01.51.7-2.01.8
Intermitt. access escalation Index2.23.15.2-2.2-1.8-2.0-2.1-1.8-1.9-1.8-1.8-1.9-2.2-1.3-1.8-1.9-1.9-1.9-1.6-1.6-1.51.0-1.6-1.2-1.52.3-0.9
Intermittent access day 1 total infusions0.71.11.91.31.41.21.21.21.11.11.01.11.31.21.11.01.11.21.21.20.9-1.00.90.00.2-0.2-0.1
Intermittent access day 15 total infusions1.62.44.91.71.71.42.01.11.51.61.61.51.41.51.71.51.61.81.31.72.2-1.81.61.50.8-0.90.4
Intermittent access terminal intake (last 3 days)3.14.05.92.32.31.92.31.82.12.12.12.02.02.12.22.02.12.31.92.12.4-2.22.01.81.2-1.00.8
Intermittent access total infusions2.93.45.42.32.21.82.21.81.92.01.92.02.02.02.11.92.02.12.02.12.0-2.01.91.00.8-0.80.2
Intermittent access day 1 locomotion3.54.57.42.72.52.62.62.22.42.22.32.12.42.12.22.12.22.32.02.22.5-2.01.91.20.8-1.40.1
Intermittent access day 15 total locomotion3.66.611.23.33.02.23.12.42.82.72.82.62.52.82.82.62.62.82.62.92.9-2.72.71.61.5-1.70.3
Intermittent access total locomotion7.48.915.23.93.53.03.73.13.33.23.23.13.23.23.23.13.13.23.13.13.1-2.92.91.51.5-1.90.6
Intermittent access standard deviation0.40.92.01.41.20.91.30.81.10.81.10.91.00.71.00.91.01.10.70.91.1-0.91.00.80.3-0.8-0.2
Left kidney weight0.10.72.60.2-0.4-0.0-0.5-0.3-0.7-0.5-0.8-0.6-0.5-0.7-1.2-0.7-0.7-0.9-0.7-1.0-0.70.9-0.9-0.9-1.60.9-1.2
Right kidney weight0.10.53.70.90.10.4-0.30.1-0.3-0.2-0.5-0.3-0.2-0.5-0.7-0.3-0.4-0.6-0.4-0.8-0.50.6-0.5-0.2-1.90.7-1.7
Cocaine induced anxiety0.50.72.3-0.5-0.5-0.1-0.7-0.6-0.7-0.7-0.8-0.9-0.7-0.9-0.9-0.9-0.8-0.8-0.9-1.0-0.81.0-1.0-0.5-1.50.7-0.7
Post-drug Anxiety0.91.03.6-0.5-0.7-0.3-0.8-0.9-0.9-0.9-1.0-1.1-1.0-1.2-1.1-1.1-1.0-1.0-1.2-1.0-0.71.2-1.0-0.4-1.90.7-1.2
Baseline Anxiety0.10.10.4-0.1-0.4-0.4-0.2-0.6-0.4-0.4-0.3-0.4-0.4-0.6-0.3-0.3-0.4-0.4-0.6-0.20.10.4-0.1-0.1-0.4-0.2-0.5
Tail length2.49.416.14.03.43.73.53.63.53.33.33.33.53.02.93.33.22.93.12.62.7-2.52.72.51.9-2.21.7
Length with tail1.87.715.13.93.32.92.93.23.13.12.93.02.82.92.42.93.02.53.12.22.3-2.82.63.11.4-1.61.0
Length without tail0.10.52.41.20.80.40.60.60.70.70.70.70.50.60.40.70.80.50.70.20.3-0.80.51.6-0.2-0.4-0.2
Times rat made contact with spout0.70.81.91.41.10.70.60.91.00.91.00.90.80.90.81.00.80.80.80.80.9-1.10.80.90.4-0.40.2
Lifetime Intake3.34.05.62.42.31.92.42.02.12.12.12.12.22.12.22.02.22.32.12.32.1-2.02.11.01.1-1.10.6
Liver weight, left3.05.010.63.33.12.12.02.92.72.42.42.42.13.01.72.32.21.82.71.41.4-2.92.11.51.2-0.20.9
Liver weight, right1.01.74.5-0.2-1.0-0.4-0.8-0.7-1.1-1.0-1.3-1.2-1.0-1.4-1.6-1.1-1.4-1.6-1.5-1.7-1.31.7-1.6-1.2-2.10.9-1.9
Locomotor activity0.60.91.90.91.30.81.40.90.90.80.80.80.91.11.10.80.61.20.71.41.0-1.20.7-0.80.70.00.5
Locomotor testing distance1.11.94.11.21.71.52.01.21.41.21.41.21.41.61.61.31.01.60.91.62.0-1.71.0-0.11.4-0.61.4
Locomotor testing rearing1.02.15.10.91.61.02.30.91.51.11.61.11.11.71.71.30.91.60.81.62.3-2.01.10.11.9-0.61.8
Locomotion in novel chamber0.50.73.20.30.1-0.1-0.4-0.3-0.2-0.2-0.3-0.5-0.90.0-0.9-0.5-0.7-0.9-0.3-1.1-0.2-0.3-1.30.8-1.71.8-1.7
Locomotion in novel chamber post-restriction0.91.53.41.21.31.50.41.51.21.41.11.41.21.31.40.91.31.31.61.70.6-1.01.21.80.4-0.60.0
Fecal boli incidents, locomotor time 10.20.21.9-0.3-0.10.40.1-0.10.00.20.20.20.00.30.30.10.10.30.20.20.5-0.40.01.20.8-0.21.4
Change in fecal boli incidents, locomotor task0.10.10.60.3-0.50.0-0.4-0.3-0.3-0.1-0.2-0.1-0.1-0.7-0.30.2-0.1-0.2-0.4-0.70.10.7-0.00.2-0.3-0.8-0.3
Time >=10cm from walls, locomotor time 13.43.67.9-2.1-1.6-1.7-2.4-1.9-1.9-1.9-1.9-2.0-2.2-1.2-2.0-2.0-2.0-1.8-1.6-2.1-1.51.0-1.9-1.2-1.92.8-1.8
Bouts of movement, locomotor time 10.30.31.1-0.5-0.7-0.30.3-0.6-0.5-0.4-0.5-0.5-0.3-0.9-0.5-0.4-0.5-0.6-0.7-0.7-0.31.0-0.7-0.50.0-1.1-0.2
Total resting periods, locomotor time 10.30.41.2-0.4-0.8-0.30.2-0.6-0.6-0.5-0.5-0.5-0.4-1.0-0.5-0.4-0.6-0.7-0.8-0.7-0.41.1-0.8-0.3-0.2-1.0-0.4
Rest time, locomotor task time 10.10.10.4-0.4-0.4-0.1-0.5-0.0-0.2-0.3-0.3-0.10.0-0.6-0.2-0.1-0.2-0.3-0.3-0.3-0.60.6-0.30.00.3-0.20.5
Distance moved, locomotor task time 10.20.31.01.00.50.20.90.40.60.60.60.50.20.50.30.40.60.40.50.30.7-0.60.70.5-0.5-0.3-0.3
Vertical activity count, locomotor time 10.10.20.50.70.60.70.20.40.50.40.50.40.20.40.00.20.40.40.40.00.6-0.50.30.7-0.70.2-0.7
Time >=10cm from walls, locomotor time 20.30.53.0-0.7-0.2-0.2-1.0-0.6-0.4-0.7-0.4-0.8-0.8-0.5-0.7-0.7-0.6-0.5-0.8-0.8-0.30.0-0.50.2-1.11.7-0.7
Bouts of movement, locomotor time 20.20.31.0-1.0-0.9-0.40.0-0.7-0.7-0.4-0.4-0.5-0.5-0.6-0.5-0.4-0.3-0.5-0.6-0.5-0.10.7-0.3-0.10.4-0.70.8
Total resting periods, locomotor time 20.30.51.6-1.3-1.1-0.6-0.2-0.9-0.9-0.6-0.7-0.7-0.7-0.8-0.8-0.7-0.5-0.7-0.8-0.8-0.40.9-0.5-0.30.2-0.60.8
Rest time, locomotor task time 22.73.46.3-2.5-2.4-1.8-2.4-2.0-2.2-2.0-2.0-1.9-1.9-2.0-1.9-2.0-1.8-1.9-1.7-2.0-1.81.9-1.7-1.0-0.50.5-0.7
Distance moved, locomotor task time 20.30.31.41.20.90.11.00.60.90.50.80.40.30.50.30.50.60.40.50.30.5-0.70.50.2-0.50.2-0.5
Vertical activity count, locomotor time 21.62.23.61.81.81.61.81.71.91.41.81.51.71.41.41.51.61.51.41.41.4-1.51.30.80.8-0.70.9
Light reinforcement 10.41.04.20.30.40.91.00.90.50.70.51.01.50.10.90.80.91.10.81.40.10.61.6-0.91.4-2.01.3
Light reinforcement 20.50.82.90.70.41.40.61.20.60.70.51.11.50.00.80.80.81.00.81.0-0.10.61.2-0.10.9-1.70.7
Bone: marrow area14.331.241.35.76.45.95.36.06.15.95.95.85.46.45.95.75.45.65.75.45.6-6.25.25.34.8-2.64.5
Bone: maximum diameter3.97.212.03.03.13.52.33.12.93.02.82.92.72.82.72.82.82.62.72.32.3-2.72.43.41.6-1.01.9
Bone: maximum force0.81.55.12.11.32.21.11.51.11.41.11.31.31.01.01.31.21.00.90.31.2-0.60.72.0-0.2-0.50.4
Bone: maximum moment0.81.55.62.11.32.41.01.51.21.31.11.21.30.91.01.21.21.00.80.21.1-0.50.72.0-0.3-0.50.4
Mean time between licks in bursts0.10.31.80.70.30.80.5-0.00.20.40.40.30.20.20.40.40.40.50.20.61.1-0.40.11.4-0.1-0.50.0
Mean num. licks in bursts0.30.51.91.30.40.41.20.50.70.60.70.60.70.30.41.00.50.40.40.20.9-0.20.60.40.5-1.40.3
Cd content in liver2.73.06.3-2.3-2.1-2.5-1.5-2.2-1.9-1.9-1.8-1.9-1.8-1.6-1.6-1.7-1.9-1.8-1.6-1.9-1.51.4-1.5-1.3-0.80.7-1.3
Co content in liver1.21.44.5-1.4-1.3-2.1-1.4-1.5-1.2-1.3-1.1-1.3-1.3-1.0-0.9-1.2-1.0-1.1-0.9-0.6-1.40.5-0.8-1.3-0.80.8-1.1
Cu content in liver0.40.51.00.30.50.70.30.80.70.70.70.81.00.40.70.70.90.80.80.70.1-0.41.00.80.8-0.50.6
Fe content in liver0.20.32.5-0.40.2-0.2-0.30.30.1-0.2-0.1-0.1-0.20.4-0.6-0.4-0.3-0.40.4-1.0-0.7-0.4-0.3-0.6-0.21.6-0.1
K content in liver0.40.41.30.30.80.3-0.11.00.60.60.40.80.60.90.50.30.70.61.20.6-0.8-0.60.6-0.30.50.30.7
Mg content in liver0.50.54.3-0.9-0.6-1.0-1.1-0.1-0.5-0.5-0.7-0.3-0.3-0.3-0.4-0.6-0.2-0.30.2-0.2-2.10.8-0.0-1.60.10.30.0
Mn content in liver0.50.64.7-0.4-0.20.0-1.10.6-0.2-0.4-0.7-0.10.0-0.1-0.4-0.6-0.3-0.40.3-0.5-2.20.9-0.4-1.6-0.81.0-0.6
Na content in liver0.60.62.20.10.90.00.21.00.80.70.70.80.81.00.70.41.00.71.50.7-0.7-1.11.0-0.41.00.30.7
Rb content in liver4.45.19.6-2.4-2.2-2.5-2.7-1.8-2.2-2.2-2.4-2.1-2.2-1.8-2.5-2.4-2.2-2.3-1.7-2.1-3.11.9-2.0-2.6-1.92.5-1.9
Se content in liver1.01.12.8-1.3-1.1-1.5-1.3-0.9-1.2-1.0-1.2-0.9-0.9-0.9-0.9-0.9-1.0-1.1-0.5-1.0-1.61.0-0.7-1.7-0.60.9-0.5
Sr content in liver0.60.51.30.90.80.80.70.60.70.70.80.60.70.30.60.70.90.70.50.90.7-0.60.91.20.2-0.70.3
Zn content in liver0.50.51.0-0.6-0.8-0.7-1.0-0.6-0.8-0.6-0.8-0.7-0.7-0.6-0.9-0.6-0.7-0.8-0.7-0.9-0.90.7-0.7-0.5-0.70.8-0.8
Bone: minimum diameter12.823.329.15.35.35.45.05.05.15.25.15.04.84.95.25.05.14.94.84.34.8-4.94.64.93.4-3.03.7
Time in familiar zone, hab. session 11.11.02.30.80.80.10.90.60.91.11.01.00.71.21.11.10.90.91.11.11.3-1.31.11.01.5-0.81.1
Time in novel zone, hab. session 11.51.52.4-1.3-1.2-0.4-1.1-1.1-1.2-1.3-1.2-1.3-1.0-1.5-1.2-1.3-1.3-1.2-1.5-1.3-1.11.5-1.3-1.0-1.50.8-1.0
Total zone transitions, hab. session 10.10.10.80.90.40.10.90.20.30.20.20.30.40.30.40.40.30.30.10.10.6-0.2-0.0-0.2-0.2-0.1-0.4
Total locomotion distance, hab. session 10.50.62.81.70.91.21.21.10.90.70.70.81.00.40.60.80.70.60.50.30.6-0.10.40.3-0.4-0.5-0.5
Locomotion velocity, hab. session 10.81.13.82.01.31.41.51.41.21.11.01.11.30.80.91.11.00.90.90.70.8-0.50.70.5-0.2-0.7-0.4
Time in familiar zone, hab. session 21.31.43.70.91.20.21.30.81.21.11.21.00.81.71.41.20.91.11.31.41.4-1.91.00.51.6-0.41.1
Time in novel zone, hab. session 21.41.54.5-0.8-1.30.1-1.4-0.6-1.2-1.1-1.3-1.0-0.7-1.8-1.3-1.1-1.0-1.1-1.4-1.3-1.42.1-1.1-0.3-1.80.4-1.3
Total zone transitions, hab. session 20.10.10.70.50.3-0.50.80.10.20.10.10.20.30.40.50.10.20.20.30.40.1-0.3-0.0-0.80.10.0-0.1
Total locomotion distance, hab. session 20.50.61.71.20.60.41.30.90.80.70.50.91.20.51.20.80.80.70.91.00.20.00.5-0.50.4-1.10.1
Locomotion velocity, hab. session 20.40.51.61.30.50.31.20.90.70.70.40.81.00.41.00.70.70.60.80.80.10.10.4-0.50.3-1.1-0.0
Novel to familiar place preference ratio0.20.21.10.50.51.00.60.40.40.50.50.40.40.20.10.50.60.40.30.30.5-0.30.50.80.1-0.50.6
Novelty place preference0.10.10.50.20.30.70.40.20.20.20.20.20.10.0-0.10.20.30.20.10.10.2-0.10.20.5-0.0-0.30.4
Time in novel zone, NPP test0.00.00.40.20.20.70.20.10.10.10.10.0-0.0-0.0-0.30.10.20.0-0.1-0.10.1-0.10.00.3-0.2-0.00.2
Total zone transitions, NPP test0.10.21.30.80.2-0.20.50.40.10.1-0.20.30.40.20.50.10.10.00.30.1-0.40.4-0.2-1.1-0.60.0-0.7
Total locomotion distance, NPP test0.50.72.61.60.90.91.21.30.90.80.60.91.20.61.10.80.60.60.80.80.30.00.3-0.2-0.3-0.6-0.6
Locomotion velocity, NPP test0.50.62.01.40.60.71.31.00.70.80.50.91.20.41.20.80.70.70.70.90.40.20.4-0.2-0.0-1.1-0.2
Intraocular pressure1.11.66.60.90.71.41.80.40.71.11.11.01.20.61.31.41.11.20.21.42.6-0.50.91.61.1-2.11.4
Delta distance traveled before/after self-admin0.10.11.4-0.1-0.0-0.30.1-0.2-0.1-0.2-0.1-0.1-0.20.2-0.2-0.3-0.3-0.10.0-0.2-0.0-0.20.2-1.20.5-0.3-0.2
Delta ambulatory time before/after self-admin0.10.10.50.40.30.20.50.30.30.30.30.30.30.50.20.10.10.40.50.00.2-0.40.5-0.60.7-0.60.2
Parametrial fat weight0.20.41.71.20.71.3-0.10.90.60.50.40.50.7-0.10.30.50.60.40.4-0.0-0.30.10.31.3-0.6-0.3-0.7
Pavlov. Cond. lever latency1.31.63.2-1.8-1.8-1.4-1.6-1.7-1.6-1.2-1.5-1.3-1.3-1.4-1.0-1.2-1.5-1.1-1.4-0.4-0.61.5-1.1-0.5-0.50.3-0.6
Pavlov. Cond. magazine entry latency3.34.26.72.42.52.12.12.62.52.12.32.22.32.11.92.12.41.92.41.61.0-2.02.21.31.6-1.11.6
Pavlov. Cond. change in total contacts2.62.84.41.62.01.72.02.02.01.71.91.81.91.71.51.72.11.61.90.90.8-1.71.70.61.4-0.91.6
Pavlov. Cond. index score2.73.45.52.22.31.82.02.32.21.92.12.02.02.01.51.92.21.72.31.10.9-2.01.91.01.3-0.81.4
Pavlov. Cond. latency score2.22.74.52.02.11.51.92.12.01.71.91.81.71.91.41.72.01.52.11.00.8-1.91.70.81.1-0.61.1
Pavlov. Cond. lever contacts1.72.03.81.92.01.51.71.81.91.41.71.51.51.51.11.41.71.31.60.50.8-1.71.30.90.8-0.40.9
Pavlov. Cond. magazine entry number2.53.25.4-1.9-2.1-1.9-1.8-2.3-2.1-1.8-1.9-2.0-2.1-1.9-1.6-1.8-2.1-1.7-2.2-1.2-0.61.7-1.9-0.8-1.50.9-1.6
Pavlov. Cond. intertrial magazine entries1.72.03.90.60.91.11.41.11.01.51.21.51.71.32.01.61.31.71.41.81.7-0.91.30.41.8-1.61.8
Pavlov. Cond. lever-magazine prob. diff.2.63.25.42.12.21.91.92.32.21.92.02.02.01.91.51.92.21.62.21.10.9-1.91.81.11.2-0.81.4
Pavlov. Cond. response bias3.64.48.62.72.72.62.12.92.62.22.32.42.42.11.72.12.41.92.51.20.8-1.92.01.31.2-0.91.4
Pavlov. Cond. lever latency0.40.51.1-0.8-1.0-0.7-0.6-0.9-0.8-0.8-0.7-0.8-0.7-1.0-0.6-0.7-0.6-0.7-0.9-0.8-0.50.9-0.7-0.2-0.60.0-0.7
Pavlov. Cond. magazine entry latency2.73.35.3-2.0-1.6-2.0-2.1-1.9-1.9-1.8-1.8-1.9-2.2-1.4-1.9-1.9-1.8-1.7-1.6-2.2-1.61.0-1.8-1.4-1.62.3-1.3
Pavlov. Cond. change in total contacts0.60.92.40.51.10.20.81.00.91.00.90.90.81.60.90.90.80.91.40.90.4-1.40.9-0.21.30.11.1
Pavlov. Cond. index score0.10.11.0-0.10.3-0.3-0.20.00.0-0.0-0.0-0.1-0.30.4-0.1-0.1-0.1-0.10.2-0.2-0.1-0.6-0.2-0.40.01.00.2
Pavlov. Cond. latency score0.10.21.9-0.30.1-0.4-0.5-0.2-0.2-0.3-0.3-0.3-0.50.2-0.5-0.3-0.3-0.3-0.1-0.5-0.3-0.4-0.5-0.5-0.31.4-0.0
Pavlov. Cond. lever contacts0.30.40.80.60.80.50.50.80.70.70.60.70.60.90.50.70.60.60.80.70.4-0.70.60.00.7-0.20.6
Pavlov. Cond. magazine entry number3.74.67.42.11.82.22.42.12.22.22.22.32.41.72.22.32.32.12.02.42.0-1.32.31.82.1-2.71.9
Pavlov. Cond. intertrial magazine entries12.919.322.64.54.24.44.54.44.54.64.64.74.83.94.44.74.74.54.24.64.2-3.44.74.14.0-4.73.8
Pavlov. Cond. lever-magazine prob. diff.0.10.11.2-0.30.2-0.3-0.4-0.1-0.2-0.2-0.2-0.2-0.40.2-0.3-0.3-0.3-0.20.0-0.3-0.3-0.4-0.3-0.5-0.11.10.0
Pavlov. Cond. response bias0.00.10.20.10.3-0.1-0.10.30.10.20.00.10.00.50.10.10.10.10.4-0.0-0.1-0.40.1-0.30.10.50.1
Time in closed arm before self-admin0.10.10.4-0.1-0.0-0.50.0-0.3-0.1-0.4-0.1-0.4-0.2-0.3-0.3-0.4-0.3-0.4-0.4-0.1-0.0-0.00.3-0.6-0.40.3-0.4
Time in closed arm after self-admin1.11.23.1-0.5-0.6-1.2-1.1-1.0-0.8-1.2-0.9-1.2-1.2-0.9-1.2-1.2-1.2-1.3-1.0-1.1-0.90.4-0.8-0.4-1.51.3-1.8
Time in open arm before self-admin1.51.73.7-1.1-1.0-0.8-1.2-1.3-1.2-1.1-1.2-1.4-1.7-1.1-1.4-1.4-1.4-1.4-1.4-1.2-0.80.8-1.60.2-1.91.7-1.6
Time in open arm after self-admin0.30.30.90.10.20.30.50.10.20.60.40.50.40.40.80.60.60.60.40.70.8-0.40.20.50.8-0.70.9
Bone: periosteal estimation8.417.727.74.74.95.34.14.84.64.54.54.44.34.44.44.34.34.24.23.63.9-4.23.84.42.9-2.03.3
Bone: periosteal perimeter3.96.712.43.13.23.42.42.92.82.92.82.62.42.72.42.52.72.52.62.02.4-3.02.43.51.1-0.71.3
Bone: post-yield work1.32.04.51.71.61.71.51.31.41.41.51.31.11.71.51.41.21.21.10.71.9-1.71.02.10.8-0.41.1
Progressive ratio test 1 active lever presses3.03.76.12.12.12.52.32.01.92.01.92.02.31.82.31.92.02.21.82.12.0-1.51.81.11.1-1.50.9
Progressive ratio test 1 breakpoint3.54.36.62.32.22.62.52.22.12.12.12.22.41.92.42.12.22.42.02.22.1-1.62.01.21.4-1.71.0
Progressive ratio test 1 inactive lever presses3.34.76.52.22.42.42.52.32.22.32.22.32.42.22.52.22.32.42.22.52.2-2.02.01.31.6-1.41.3
Progressive ratio test 2 active lever presses6.17.110.92.92.93.32.92.72.72.92.72.82.92.52.92.72.83.02.62.82.8-2.32.62.31.7-1.91.4
Progressive ratio test 2 breakpoint6.77.711.23.03.03.43.02.82.83.02.82.93.02.73.02.82.93.12.62.93.0-2.52.72.51.8-1.91.5
Progressive ratio test 2 inactive lever presses2.84.56.82.52.12.32.62.12.12.32.12.32.41.82.52.22.32.41.92.62.2-1.42.31.41.4-2.21.0
Incentive Sensitization - Responses3.14.35.92.12.32.32.22.12.12.42.22.22.02.22.02.12.12.22.12.02.2-2.22.12.31.4-1.21.2
Incentive Sensitization - Breakpoint3.34.25.72.22.32.22.22.02.12.42.12.11.92.22.02.12.12.22.02.02.3-2.22.12.31.3-1.11.2
Sum of active levers in priming session hrs 5-60.50.42.4-1.6-0.8-1.0-0.4-0.9-0.7-0.7-0.5-0.6-0.5-0.4-0.2-0.7-0.4-0.3-0.4-0.2-0.30.2-0.4-1.00.90.20.6
Progressive ratio0.10.10.40.20.20.1-0.30.30.10.20.10.30.10.30.30.00.30.20.60.4-0.1-0.30.30.50.3-0.30.3
Food seeking constrained by brief footshock3.34.07.32.02.31.22.31.82.21.92.21.91.62.32.21.92.02.02.12.21.9-2.72.11.82.2-1.11.7
Seeking ratio, punishment vs. effort1.21.84.01.31.41.02.01.21.51.31.51.31.21.51.41.51.21.31.11.41.5-1.61.21.01.3-0.51.2
Retroperitoneal fat weight0.52.14.72.21.41.51.81.41.51.41.41.51.60.91.61.61.41.31.11.41.4-0.71.51.30.9-2.00.5
Reaction time number correct0.30.71.8-0.4-0.7-0.3-0.6-0.7-1.0-0.7-1.0-0.7-0.7-0.9-0.6-0.8-0.9-0.7-0.9-0.7-0.51.1-0.8-0.5-1.30.4-1.3
Reaction time mean minus median0.10.30.6-0.6-0.8-0.6-0.5-0.7-0.5-0.5-0.4-0.6-0.6-0.6-0.4-0.5-0.6-0.6-0.6-0.5-0.20.6-0.6-0.1-0.30.1-0.3
Reaction time mean minus median AUC0.71.72.4-1.3-1.6-1.4-1.5-1.2-1.4-1.3-1.4-1.3-1.3-1.2-1.1-1.4-1.3-1.4-1.1-1.3-1.41.4-1.4-1.2-1.21.0-1.1
Reaction time num false alarms2.94.16.32.42.51.91.72.22.22.12.12.12.02.22.01.92.22.22.12.51.9-2.32.31.51.4-0.81.1
Reaction time num false alarms AUC2.94.67.02.52.62.11.82.42.32.32.22.32.22.22.12.02.42.32.32.51.7-2.32.51.61.4-1.01.1
Reaction time trials correct on left0.30.71.8-0.4-0.7-0.3-0.6-0.7-1.0-0.7-1.0-0.7-0.7-0.9-0.6-0.8-0.9-0.7-0.9-0.7-0.51.1-0.8-0.5-1.30.4-1.3
Reaction time trials on left0.30.61.8-0.4-0.7-0.3-0.6-0.6-1.0-0.7-1.0-0.7-0.7-0.9-0.6-0.8-0.9-0.7-0.9-0.6-0.51.1-0.8-0.4-1.30.3-1.3
Reaction time mean0.81.32.6-1.3-1.2-0.9-1.6-0.8-1.0-1.1-1.2-1.1-1.1-0.9-0.9-1.3-1.3-1.2-0.9-1.2-1.41.1-1.4-1.1-0.81.4-0.5
Reaction time mean AUC1.11.83.1-1.7-1.5-1.3-1.8-1.0-1.2-1.4-1.3-1.3-1.3-1.1-1.1-1.5-1.4-1.4-1.1-1.3-1.51.2-1.6-1.3-0.81.5-0.5
Median of all reaction times1.01.42.9-1.4-1.2-0.9-1.7-0.7-1.1-1.2-1.2-1.1-1.1-0.9-1.0-1.3-1.3-1.3-0.9-1.2-1.51.1-1.4-1.2-0.91.5-0.5
Reaction time omissions0.10.20.90.6-0.00.90.20.60.30.50.30.50.6-0.10.20.40.20.20.20.40.30.6-0.00.70.0-0.90.3
Reaction time false alarm rate3.24.56.42.32.51.81.82.32.42.22.42.22.12.32.02.02.42.22.32.41.7-2.52.31.71.8-0.91.6
Reaction time premature initiation rate1.11.53.31.01.01.61.61.01.11.21.21.21.50.61.41.31.21.50.91.51.3-0.61.50.61.4-1.81.0
Reaction time premature initiations0.40.82.40.80.71.21.10.70.60.80.60.81.10.21.10.80.71.10.51.20.9-0.11.10.30.7-1.60.2
Std. dev. reaction times0.30.51.0-0.8-1.0-0.8-1.0-0.6-0.7-0.7-0.7-0.7-0.8-0.7-0.7-0.8-0.8-0.8-0.6-0.8-0.90.9-0.9-0.3-0.50.5-0.4
Reaction time trials completed0.30.61.8-0.4-0.7-0.3-0.6-0.6-1.0-0.7-1.0-0.7-0.7-0.9-0.6-0.8-0.9-0.7-0.9-0.6-0.51.1-0.8-0.4-1.30.3-1.3
Reaction time trials AUC0.30.61.9-0.4-0.7-0.3-0.6-0.7-1.0-0.7-1.0-0.7-0.7-0.9-0.6-0.8-0.9-0.7-0.9-0.7-0.51.1-0.7-0.5-1.30.3-1.4
Run reversals in cocaine runway, females0.50.51.5-0.1-0.9-0.1-0.1-0.9-0.5-0.4-0.3-0.6-0.6-1.2-0.5-0.4-0.3-0.5-1.2-0.30.41.0-0.60.9-0.9-0.7-0.9
Run reversals in cocaine runway, males0.20.20.8-0.4-0.40.1-0.3-0.5-0.4-0.3-0.2-0.4-0.5-0.5-0.5-0.3-0.4-0.4-0.5-0.50.10.2-0.20.9-0.70.5-0.3
Latency to leave start box in cocaine runway0.30.30.7-0.7-0.5-0.3-0.5-0.6-0.6-0.6-0.5-0.6-0.5-0.5-0.6-0.6-0.6-0.4-0.7-0.4-0.30.4-0.3-0.1-0.70.9-0.8
Latency to leave start box in cocaine runway, F0.70.81.4-1.0-0.9-0.4-0.5-1.0-0.9-0.9-0.8-1.0-1.0-0.8-1.1-1.0-0.9-1.0-1.1-1.1-0.30.6-1.10.2-1.21.1-0.8
Latency to leave start box in cocaine runway, M0.20.10.70.00.30.0-0.10.40.30.20.30.40.40.30.40.20.20.60.40.7-0.1-0.20.9-0.50.40.3-0.2
Std. dev. time between licks in bursts0.00.10.30.0-0.10.10.4-0.2-0.00.10.10.00.1-0.10.30.10.20.10.00.10.30.1-0.10.30.2-0.60.5
Total sessions with >9 infusions0.30.31.20.70.50.61.00.20.40.40.50.50.70.30.60.50.60.70.20.81.1-0.30.5-0.20.1-0.6-0.1
Short access day 1 total inactive lever presses1.72.34.32.11.71.72.01.61.61.61.61.51.61.31.51.61.61.51.11.71.8-1.21.51.40.4-1.30.1
Short access day 10 total inactive lever presses0.20.41.60.30.10.70.80.40.40.50.50.50.7-0.10.90.60.60.70.20.90.60.30.80.70.6-1.31.0
Short access day 1 total infusions0.40.51.20.70.60.70.90.70.60.70.70.81.00.70.80.70.90.90.61.10.9-0.40.8-0.50.5-0.60.4
Short access day 10 total infusions2.93.75.52.12.01.92.31.82.01.92.02.02.11.82.22.02.12.21.82.42.2-1.82.01.01.3-1.21.1
Short access total infusions1.51.93.01.41.41.41.61.41.41.41.41.41.61.41.51.41.51.61.31.71.5-1.21.40.30.9-0.80.9
Short access day 1 locomotion2.12.65.81.81.32.12.01.31.41.61.71.61.91.11.81.71.81.81.21.72.4-1.01.41.01.0-1.90.7
Short access day 10 total locomotion4.27.912.73.33.02.63.62.73.12.83.12.82.92.63.12.92.92.92.73.13.0-2.72.81.72.1-2.51.3
Short access total locomotion3.13.76.72.41.92.12.61.72.01.92.11.92.11.72.12.02.12.11.62.12.6-1.71.81.21.1-1.80.6
One hour access (0.3 mA shock)1.21.42.31.01.31.21.21.01.11.31.31.21.11.31.11.21.21.31.11.11.4-1.51.01.51.1-0.31.0
Compulsive drug intake0.91.12.0-1.0-0.9-0.8-1.1-0.9-1.1-1.0-1.1-1.2-1.3-1.0-1.4-1.1-1.2-1.3-1.1-1.0-1.10.8-1.2-0.1-1.11.0-0.4
One hour access (shock baseline)1.52.33.21.51.61.41.71.41.61.61.61.61.71.61.71.61.71.81.61.51.7-1.61.61.11.2-0.80.6
Social response proportion0.30.30.9-0.2-0.5-0.4-0.3-0.9-0.6-0.5-0.4-0.6-0.8-0.5-0.6-0.3-0.5-0.5-0.8-0.60.50.1-0.50.7-0.60.2-0.8
Social responses0.10.10.50.10.40.10.50.00.20.20.30.20.10.50.30.40.20.40.10.20.7-0.60.30.10.20.10.1
Social time0.10.22.0-0.00.10.5-0.1-0.30.10.10.4-0.0-0.20.20.20.20.00.1-0.20.11.2-0.6-0.21.4-0.00.20.3
Soleus weight0.10.31.40.60.50.30.60.30.40.60.60.40.20.50.20.50.60.40.30.30.7-0.80.71.20.2-0.1-0.1
Bone: stiffness0.30.51.51.20.90.80.51.00.60.80.50.80.71.20.80.70.60.60.9-0.00.5-0.80.40.50.00.50.2
Tibialis anterior weight0.31.06.40.0-0.1-0.81.3-0.50.40.60.90.50.50.11.00.81.10.90.40.71.3-0.71.41.31.5-2.50.9
Time to tail flick, vehicle, before self-admin0.60.63.6-0.3-0.20.1-1.2-0.0-0.4-0.3-0.5-0.4-0.6-0.3-0.8-0.6-0.5-0.6-0.3-0.7-0.80.3-1.30.9-1.61.9-0.8
Time to tail flick, vehicle, after self-admin0.10.10.20.00.10.3-0.40.40.00.3-0.10.30.40.00.30.30.20.10.30.4-0.30.20.10.4-0.1-0.00.4
Time to tail flick, test, before self-admin0.20.20.9-0.6-0.2-0.9-0.3-0.5-0.2-0.5-0.2-0.5-0.7-0.2-0.5-0.3-0.4-0.6-0.4-0.5-0.1-0.2-0.2-0.10.30.40.3
Time to tail flick, test, after self-admin0.00.00.2-0.10.0-0.30.10.20.00.2-0.00.10.0-0.00.3-0.10.2-0.10.20.1-0.40.00.3-0.30.20.10.4
Delta time to tail flick, vehicle, before/after SA1.61.53.81.00.90.71.11.11.21.11.11.31.40.81.51.31.31.21.11.40.9-0.71.70.51.8-1.91.3
Delta time to tail flick, test, before/after SA0.10.10.60.10.1-0.1-0.20.40.00.2-0.20.20.20.10.3-0.20.20.10.40.1-0.80.20.2-0.5-0.30.4-0.2
Tibia length0.20.53.60.90.00.3-0.60.1-0.3-0.3-0.5-0.3-0.4-0.3-0.9-0.3-0.5-0.5-0.4-0.7-0.60.6-0.4-0.3-1.81.1-1.9
Ambulatory time before self-admin0.30.42.3-0.9-0.2-0.2-1.0-0.5-0.6-0.6-0.5-0.6-0.7-0.3-0.8-0.7-0.6-0.6-0.5-0.5-0.4-0.0-0.60.4-0.81.5-0.5
Ambulatory time after self-admin0.00.10.3-0.30.10.1-0.4-0.0-0.1-0.1-0.0-0.1-0.20.3-0.3-0.3-0.2-0.00.0-0.20.1-0.40.00.00.10.60.1
Bone: tissue strength1.61.73.8-0.7-1.1-1.0-1.3-1.0-1.3-1.2-1.4-1.2-1.2-0.9-1.3-1.2-1.4-1.4-1.2-2.0-1.11.1-1.7-1.0-1.61.5-1.4
Total heroin consumption0.40.51.40.21.10.60.21.00.80.50.60.60.71.20.30.40.50.41.00.70.1-1.20.2-0.30.51.10.5
Bone: trabecular number1.32.26.42.11.72.50.72.51.71.71.31.82.01.21.21.31.61.31.81.20.1-0.61.21.00.3-0.50.6
Bone: trabecular spacing0.30.42.3-1.0-0.5-1.50.1-1.3-0.7-0.7-0.4-0.7-0.9-0.2-0.0-0.5-0.6-0.3-0.6-0.10.3-0.3-0.4-0.60.30.40.2
Bone: trabecular thickness1.92.39.12.11.53.01.02.11.61.71.51.71.80.60.91.41.71.41.21.10.8-0.31.42.20.2-1.50.8
Bone: trabecular tissue density1.31.94.6-0.3-1.4-0.4-1.2-0.8-1.4-1.2-1.6-1.1-0.9-1.5-1.4-1.1-1.4-1.6-1.5-1.8-1.32.1-1.7-0.9-2.20.8-1.6
Water consumed over 24 hours0.10.10.50.70.30.1-0.00.20.30.20.20.20.30.0-0.00.30.20.1-0.0-0.20.10.00.20.1-0.3-0.3-0.6
Number of responses in last shaping day0.10.10.70.30.30.80.40.20.30.30.40.20.30.00.30.30.40.3-0.10.50.7-0.1-0.10.9-0.2-0.20.2