Hub : Genes

Strada

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC isoform ratio NM_001415111.1 0.18 0.1 2.1e-03 0.06 0.06 0.08 0.08 1.5e-02 1.3e-02 7.1e-03 5.2e-03
2 BLA mRNA stability Strada 0.08 0.04 2.0e-05 0.1 0.08 0.08 0.09 9.2e-06 4.8e-05 2.9e-05 1.9e-05
3 IL mRNA stability Strada 0.34 0.11 2.5e-07 0.3 0.24 0.28 0.23 5.8e-08 2.2e-06 2.2e-07 2.4e-06
4 Liver mRNA stability Strada 0.02 0.02 6.3e-03 0 0.01 0 0 3.1e-01 2.6e-02 3.6e-01 3.4e-01
5 BLA gene expression Strada 0.31 0.11 0.0e+00 0.33 0.35 0.37 0.36 1.5e-18 1.2e-19 5.3e-21 2.5e-20
6 RMTg intron excision ratio chr10_91117571_91123739 0.09 0.06 8.9e-03 0.05 0.05 0.04 0.03 2.0e-02 1.7e-02 3.0e-02 4.9e-02
7 IL gene expression Strada 0.35 0.15 3.4e-05 0.1 0.1 0.08 0.11 2.1e-03 1.9e-03 5.0e-03 1.4e-03
8 PL gene expression Strada 0.21 0.07 0.0e+00 0.31 0.32 0.3 0.32 1.7e-34 5.9e-36 8.4e-34 1.7e-36
9 LHb mRNA stability Strada 0.14 0.09 9.3e-03 0.03 0.04 -0 0.01 6.9e-02 4.8e-02 4.4e-01 1.5e-01
10 NAcc mRNA stability Strada 0.08 0.03 3.0e-14 0.12 0.12 0.12 0.12 6.2e-14 9.7e-14 2.4e-14 2.1e-13
11 NAcc gene expression Strada 0.15 0.06 0.0e+00 0.21 0.23 0.23 0.22 4.6e-24 2.8e-26 1.7e-26 1.4e-25
12 Brain mRNA stability Strada 0.23 0.07 0.0e+00 0.34 0.35 0.36 0.36 5.9e-33 8.6e-34 1.1e-34 6.4e-35
13 PL mRNA stability Strada 0.2 0.08 0.0e+00 0.28 0.27 0.27 0.28 1.5e-30 8.2e-30 7.8e-30 4.7e-31
14 Adipose mRNA stability Strada 0.2 0.07 0.0e+00 0.25 0.27 0.27 0.27 5.3e-27 1.1e-29 2.1e-30 5.0e-30
15 NAcc intron excision ratio chr10_91104254_91111276 0.02 0.01 4.2e-03 0.02 0.01 0 0.01 4.5e-03 3.2e-02 1.8e-01 2.1e-02
16 NAcc intron excision ratio chr10_91111304_91114911 0.02 0.02 2.7e-03 0.02 0.01 0.01 0.01 7.0e-04 1.1e-02 5.7e-02 1.9e-02
17 Brain gene expression Strada 0.13 0.05 3.1e-15 0.18 0.16 0.16 0.17 3.9e-16 4.7e-15 1.0e-14 7.8e-16
18 pVTA gene expression Strada 0.12 0.06 4.8e-05 0.12 0.09 0.04 0.09 1.1e-05 1.4e-04 6.7e-03 1.4e-04
19 OFC mRNA stability Strada 0.5 0.14 6.5e-08 0.24 0.26 0.22 0.25 2.6e-06 5.9e-07 6.4e-06 9.6e-07
20 Adipose intron excision ratio chr10_91104254_91117516 0.04 0.02 1.1e-03 0.01 0.02 0.01 0.01 2.7e-02 4.9e-03 2.5e-02 5.6e-02
21 Brain isoform ratio NM_001415111.1 0.03 0.02 4.3e-03 0.01 0 0 0 7.3e-02 2.1e-01 2.3e-01 1.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.22.06.72.5-1.9-2.62.3-1.01.41.31.61.5-0.9-1.41.31.4-1.5-0.6-0.6-1.0-1.0-0.2-0.3-0.4
Area under the delay curve0.10.10.30.1-0.2-0.50.4-0.10.20.50.30.3-0.2-0.30.20.2-0.4-0.2-0.2-0.2-0.20.1-0.1-0.2
BMI with tail0.20.73.8-0.70.3-0.1-1.0-1.30.5-0.10.3-0.1-0.50.70.50.30.9-0.9-0.9-0.6-0.62.0-1.60.9
BMI without tail1.83.68.40.9-1.0-1.81.0-2.61.91.62.01.6-2.1-1.02.21.9-0.9-2.2-2.2-2.3-2.32.9-2.90.2
Body weight1.98.114.52.1-3.0-2.62.2-3.63.23.02.82.7-3.2-2.43.03.0-2.0-3.2-3.2-3.1-3.13.8-2.4-1.0
Weight adjusted by age0.50.61.6-1.11.31.0-1.00.9-0.8-0.5-0.8-0.80.50.7-0.7-0.70.70.60.60.60.6-0.20.60.0
Bone surface4.98.618.24.3-3.9-4.24.0-2.63.43.33.03.0-2.6-3.22.72.8-3.0-2.2-2.2-2.4-2.41.7-0.4-1.5
Bone volume4.27.115.03.8-3.4-3.93.6-2.43.02.92.82.8-2.3-2.82.52.7-2.7-1.9-1.9-2.2-2.21.4-0.7-1.3
Breakpoint value in progressive ratio session1.01.12.11.2-0.8-0.81.0-0.71.01.11.01.1-1.3-1.11.21.1-1.2-0.9-0.9-1.4-1.40.9-0.4-0.8
Number of licking bursts0.10.10.60.10.00.1-0.00.5-0.00.2-0.1-0.1-0.10.0-0.1-0.00.10.30.30.10.1-0.10.80.3
Context. condit. distance diff. score0.20.21.1-0.90.31.0-0.8-0.0-0.4-0.2-0.4-0.40.10.5-0.2-0.40.2-0.1-0.1-0.1-0.10.20.00.7
Locomotion velocity, session 11.01.12.81.5-1.7-1.61.5-1.31.10.91.11.0-0.8-1.11.10.9-0.9-0.6-0.6-0.9-0.90.4-0.4-0.6
Locomotion distance, session 10.10.10.40.2-0.6-0.50.6-0.40.10.20.10.30.0-0.10.10.1-0.1-0.1-0.10.10.1-0.1-0.20.4
Locomotion velocity, session 20.30.41.31.1-1.0-0.61.1-0.50.60.50.40.8-0.5-0.90.40.5-0.9-0.4-0.4-0.2-0.20.10.2-0.1
Locomotion distance, session 20.10.10.5-0.1-0.50.30.4-0.2-0.20.2-0.30.1-0.0-0.1-0.2-0.2-0.20.00.00.30.3-0.30.50.7
Locomotion velocity, session 30.40.52.2-0.30.30.5-0.50.6-0.5-0.6-0.6-0.70.80.7-0.6-0.50.60.80.80.50.5-0.81.01.5
Locomotion distance, session 30.10.10.80.4-0.3-0.00.20.30.10.1-0.2-0.10.2-0.1-0.2-0.0-0.00.30.30.20.2-0.30.90.5
Stereotopy head waving bouts, day 30.30.31.2-0.20.5-0.0-0.20.6-0.6-0.6-0.3-0.50.80.5-0.5-0.50.40.70.70.60.6-1.10.20.3
Stereotopy head waving duration, day 30.20.20.7-0.60.60.4-0.40.6-0.7-0.3-0.3-0.50.50.5-0.4-0.40.30.50.50.30.3-0.80.20.5
Locomotion velocity, session 70.40.40.9-0.60.30.7-0.60.5-0.7-0.9-0.7-0.70.90.8-0.7-0.70.60.70.70.70.7-0.80.30.5
Locomotion distance, session 70.00.10.2-0.50.30.40.00.1-0.2-0.0-0.20.1-0.00.2-0.0-0.2-0.2-0.3-0.3-0.0-0.00.2-0.30.3
Stereotopy head waving bouts, day 70.50.51.8-0.20.30.4-0.30.7-0.7-0.6-0.6-0.60.80.6-0.8-0.60.60.70.70.80.8-1.20.91.3
Stereotopy head waving duration, day 71.82.25.1-1.00.91.4-1.01.7-1.7-1.3-1.5-1.41.61.3-1.6-1.31.01.61.61.51.5-2.31.81.5
Locomotion velocity, session 80.40.51.60.2-1.30.20.3-0.80.80.70.50.5-0.9-0.70.60.8-0.7-0.7-0.7-0.9-0.91.0-0.1-0.7
Locomotion distance, session 80.10.10.7-0.5-0.30.80.0-0.4-0.20.2-0.10.2-0.3-0.10.10.1-0.5-0.4-0.4-0.3-0.30.0-0.10.4
Degree of sensitization distance0.30.31.4-0.5-0.10.10.2-0.60.20.50.30.6-0.7-0.30.60.2-0.6-0.9-0.9-0.6-0.60.9-1.2-0.6
Degree of sensitization stereotypy1.31.44.0-0.70.61.1-0.81.0-1.1-1.1-1.2-1.11.21.1-1.3-1.11.01.01.01.31.3-1.41.42.0
Conditioned locomotion0.80.92.00.4-0.4-0.50.8-0.90.60.90.91.1-1.0-0.90.91.0-1.1-1.3-1.3-0.9-0.90.9-1.4-0.9
Cocaine response after cond. corrected0.40.41.7-0.30.40.2-0.60.8-0.3-0.2-0.6-0.80.60.6-0.7-0.61.10.60.60.70.7-0.21.30.1
Cocaine response after cond. not corrected0.91.05.20.10.20.2-0.61.1-0.4-0.5-0.8-1.00.90.8-1.0-0.91.21.21.21.11.1-0.82.30.7
Cocaine response before conditioning0.30.31.60.5-0.10.00.20.5-0.3-0.3-0.3-0.30.40.3-0.5-0.40.00.80.80.50.5-1.11.31.1
Saline control response1.82.44.70.9-0.8-1.01.1-2.01.31.21.51.6-1.7-1.31.71.5-1.6-2.1-2.1-1.7-1.71.8-2.2-0.8
Bone: connectivity density1.82.97.42.7-2.2-2.72.7-1.31.71.81.81.9-1.2-1.71.51.5-2.0-1.1-1.1-1.2-1.20.2-0.4-0.7
Bone: cortical apparent density3.95.18.1-2.52.72.1-2.12.3-2.8-2.5-2.1-2.22.52.7-2.2-2.12.02.22.22.02.0-2.80.62.1
Bone: cortical area1.52.36.12.3-1.7-2.51.8-1.91.91.51.61.4-1.2-1.41.51.6-0.9-1.1-1.1-1.3-1.31.1-0.50.6
Bone: cortical porosity6.97.620.04.5-3.5-3.52.9-3.03.82.32.92.5-2.7-2.92.62.8-1.9-2.2-2.2-2.2-2.22.9-0.3-1.3
Bone: cortical porosity3.94.312.23.5-2.7-2.82.2-2.33.01.82.21.8-2.0-2.11.82.1-1.3-1.5-1.5-1.5-1.52.30.1-0.4
Bone: cortical thickness3.55.815.3-1.42.21.0-2.01.8-2.1-2.7-2.1-2.52.82.8-2.3-2.03.02.62.62.32.3-2.71.53.9
Bone: cortical thickness3.84.410.5-1.01.81.1-1.61.7-1.8-2.5-1.9-2.12.42.5-2.1-2.02.42.22.22.22.2-2.31.53.2
Bone: cortical tissue density3.84.97.8-2.52.72.1-2.12.3-2.7-2.4-2.1-2.22.42.6-2.1-2.02.02.22.21.91.9-2.80.52.0
Condit. Reinf. active minus inactive responses3.03.44.32.1-1.8-1.92.0-2.01.91.81.92.0-1.9-1.81.91.7-2.0-2.1-2.1-1.7-1.71.8-1.2-0.7
Condit. Reinf. active-inactive response ratio1.31.42.01.4-1.3-1.31.3-1.21.21.21.31.2-1.2-1.21.21.0-1.4-1.3-1.3-1.1-1.11.1-0.6-0.3
Condit. Reinf. active responses3.94.76.42.2-2.0-2.02.4-2.22.12.32.22.4-2.3-2.22.22.2-2.5-2.4-2.4-2.2-2.21.9-1.6-1.2
Condit. Reinf. inactive responses1.21.52.21.0-1.1-1.01.5-1.01.11.51.21.4-1.3-1.31.21.5-1.5-1.2-1.2-1.3-1.30.7-1.0-0.9
Incentive salience index mean2.63.15.32.3-2.0-2.02.2-1.91.91.71.81.9-1.7-1.91.71.8-2.0-1.7-1.7-1.6-1.61.2-0.9-0.8
Condit. Reinf. lever presses0.40.51.11.0-1.0-0.61.0-0.70.70.50.60.8-0.5-0.90.60.9-0.9-0.4-0.4-0.7-0.7-0.1-0.2-0.3
Condit. Reinf. active minus inactive responses5.87.112.53.5-3.2-3.23.5-2.52.83.32.92.9-2.8-2.72.72.6-3.0-2.3-2.3-2.3-2.31.8-0.5-0.5
Condit. Reinf. active-inactive response ratio3.73.98.12.9-2.5-2.62.6-1.72.12.22.22.1-2.0-2.12.01.9-2.1-1.5-1.5-1.7-1.71.2-0.3-0.8
Condit. Reinf. active responses6.69.113.63.4-3.1-3.33.7-3.03.03.53.33.4-3.2-3.13.13.0-3.4-3.0-3.0-2.8-2.82.4-1.6-1.3
Condit. Reinf. inactive responses2.32.84.91.2-1.1-1.31.8-1.91.41.71.61.9-1.7-1.51.71.7-2.0-2.2-2.2-1.6-1.61.5-1.9-0.6
Condit. Reinf. lever presses1.72.33.71.9-1.6-1.61.8-1.71.61.41.61.6-1.5-1.31.61.5-1.6-1.5-1.5-1.4-1.41.3-0.8-0.0
Condit. Reinf. lever reinforcers received5.67.911.93.3-2.8-3.23.4-2.72.83.23.13.1-2.9-2.82.92.8-3.1-2.8-2.8-2.5-2.52.2-1.5-1.2
Conditioned reinforcement - actives0.80.81.40.6-0.8-0.80.7-1.01.00.90.90.9-1.0-0.80.90.9-0.8-0.9-0.9-1.0-1.01.2-0.9-0.3
Conditioned reinforcement - inactives1.11.21.91.1-1.4-1.21.1-1.41.31.11.11.1-1.2-1.01.11.1-0.9-1.1-1.1-1.0-1.01.3-0.9-0.1
Conditioned locomotion2.73.24.21.9-1.9-2.01.8-1.92.11.71.91.8-1.9-1.71.91.8-1.7-1.6-1.6-1.8-1.81.9-1.5-1.2
Patch foraging indifference point 0 sec4.77.69.82.4-2.6-2.73.0-3.12.53.02.93.1-2.7-2.82.92.7-2.9-3.1-3.1-2.7-2.72.3-2.6-1.3
Patch foraging indifference point AUC1.21.42.00.6-1.0-0.70.9-1.21.01.31.11.2-1.2-1.31.11.2-1.3-1.4-1.4-1.3-1.31.1-1.1-1.4
Delay disc. indifference point, 0s delay0.50.61.4-0.81.10.7-0.61.2-0.9-0.5-0.7-0.60.70.5-0.7-0.70.40.90.90.60.6-1.00.60.0
Delay disc. indifference point, 16s delay0.40.40.90.6-0.1-1.00.6-0.50.70.80.80.7-0.7-0.50.60.7-0.7-0.6-0.6-0.5-0.50.8-0.6-0.1
Delay disc. indifference point, 2s delay0.50.61.80.6-0.9-0.91.3-0.20.41.30.70.9-0.6-0.90.60.6-1.1-0.4-0.4-0.5-0.5-0.40.1-0.7
Delay disc. indifference point, 24s delay2.12.02.71.0-1.2-1.51.3-1.51.51.61.51.5-1.5-1.31.51.5-1.5-1.6-1.6-1.3-1.31.6-1.5-0.8
Delay disc. indifference point, 4s delay0.80.81.8-0.50.70.5-0.60.9-0.7-0.8-0.9-0.91.00.8-1.0-0.90.81.01.01.11.1-0.91.40.7
Delay disc. indifference point, 8s delay0.10.10.4-0.30.3-0.10.10.4-0.4-0.1-0.2-0.20.50.3-0.2-0.30.10.20.20.30.3-0.70.0-0.0
Indifference point function ln k0.20.32.60.20.5-0.3-0.00.5-0.4-0.3-0.2-0.40.50.5-0.3-0.20.60.80.80.40.4-0.90.51.6
Indifference point function log k0.20.32.60.20.5-0.3-0.00.5-0.4-0.3-0.2-0.40.50.5-0.3-0.20.60.80.80.40.4-0.90.51.6
Patch foraging total patch changes 0 sec5.18.110.42.5-2.7-2.93.1-3.22.73.23.03.1-2.8-2.93.02.8-2.9-3.2-3.2-2.8-2.82.5-2.6-1.4
Patch foraging total patch changes 12 sec5.77.410.51.9-2.6-2.02.9-2.72.33.12.63.1-2.8-3.02.72.6-3.2-3.2-3.2-2.7-2.72.2-2.4-2.6
Patch foraging total patch changes 18 sec3.03.95.71.7-1.8-1.71.9-2.32.02.01.92.1-2.0-2.02.01.9-1.7-2.4-2.4-1.9-1.92.3-1.7-1.3
Patch foraging total patch changes 24 sec4.25.17.22.2-2.3-2.42.7-2.32.12.52.32.5-2.2-2.32.32.3-2.4-2.6-2.6-2.1-2.11.7-1.8-1.1
Patch foraging total patch changes 6 sec2.63.95.01.9-2.0-2.02.1-2.21.92.12.02.1-1.9-2.12.02.0-2.0-2.2-2.2-2.0-2.01.7-1.5-1.1
Patch foraging time to switch 0 sec0.20.30.8-0.30.40.6-0.60.5-0.4-0.9-0.7-0.60.60.5-0.5-0.60.50.50.50.50.5-0.40.50.2
Patch foraging water rate 0 sec1.62.53.71.4-1.7-1.91.6-1.91.71.51.71.6-1.6-1.41.71.6-1.3-1.8-1.8-1.4-1.41.7-1.8-0.5
Patch foraging water rate 12 sec1.21.85.1-0.70.90.4-1.11.1-0.9-1.2-1.1-1.51.41.6-1.3-1.31.81.51.51.51.5-1.01.62.3
Patch foraging water rate 18 sec0.30.32.70.4-0.5-0.50.40.4-0.20.2-0.0-0.20.50.3-0.3-0.30.30.50.50.60.6-0.91.01.6
Patch foraging water rate 24 sec0.10.10.9-0.0-0.40.00.00.4-0.10.2-0.2-0.20.20.3-0.2-0.30.30.20.20.30.3-0.20.91.0
Patch foraging water rate 6 sec0.10.21.30.5-0.0-0.90.30.20.0-0.10.2-0.20.40.40.0-0.10.40.50.50.20.2-0.50.31.2
Seeking ratio, delayed vs. immediate footshock0.10.10.8-0.1-0.10.0-0.2-0.60.2-0.10.20.2-0.20.00.20.1-0.2-0.7-0.7-0.1-0.10.7-0.90.1
Distance traveled before self-admin0.60.74.00.00.60.4-0.81.0-0.2-0.1-0.6-0.90.30.4-0.7-0.61.11.11.10.60.6-0.12.00.9
Distance traveled after self-admin0.30.42.80.00.30.6-0.60.50.00.0-0.5-0.5-0.00.2-0.6-0.50.60.60.60.60.60.41.70.9
Extensor digitorum longus weight1.03.813.2-3.63.22.8-3.51.2-1.8-2.4-1.7-2.01.22.0-1.2-1.22.40.70.70.60.60.3-1.7-0.8
Bone: elastic displacement2.02.33.6-0.70.71.0-1.31.3-1.2-1.7-1.3-1.61.71.6-1.6-1.41.71.91.91.61.6-1.51.71.8
Bone: elastic work0.10.20.60.7-0.6-0.60.1-0.20.4-0.60.2-0.30.40.2-0.10.10.60.60.60.30.3-0.30.30.6
Bone: endosteal estimation14.331.238.16.2-6.1-5.86.0-5.66.16.15.85.8-5.9-6.15.65.4-5.7-5.4-5.4-5.2-5.25.5-2.8-4.3
Bone: endosteal perimeter16.033.242.76.2-6.4-5.96.0-5.96.56.55.85.9-6.2-6.55.85.7-5.7-5.5-5.5-5.5-5.55.9-2.7-4.4
Epididymis fat weight1.12.55.81.0-1.1-1.71.1-1.81.61.21.61.4-1.6-1.21.71.6-0.9-1.8-1.8-1.5-1.52.0-2.4-1.7
Delta time in closed arm before/after self-admin0.10.11.00.2-0.80.20.10.1-0.0-0.1-0.3-0.20.3-0.0-0.3-0.30.10.40.40.40.4-0.41.00.2
Delta time in open arm before/after self-admin0.30.31.8-0.81.40.5-0.60.6-0.6-0.3-0.1-0.20.10.5-0.0-0.00.3-0.0-0.0-0.1-0.1-0.2-1.00.1
Diff in mean of infusions in LGA sessions0.80.91.7-1.11.21.1-1.30.7-0.9-1.2-1.0-1.10.91.1-0.9-0.91.20.90.90.60.6-0.50.30.7
Delay discount exponential model param0.20.30.6-0.40.50.7-0.60.4-0.5-0.8-0.5-0.50.50.5-0.5-0.50.70.50.50.40.4-0.40.20.5
Extinction: sum of active levers before priming0.50.51.30.20.2-0.20.4-0.60.40.90.70.7-1.0-0.80.90.8-0.9-0.6-0.6-1.1-1.10.8-0.9-0.6
Active lever presses in extinction session 62.52.43.31.8-1.1-1.71.4-1.71.81.41.61.5-1.7-1.71.71.7-1.3-1.5-1.5-1.7-1.71.8-1.2-1.0
Bone: final force0.50.82.81.6-1.4-1.71.4-0.91.11.10.90.8-0.6-0.90.70.7-0.6-0.3-0.3-0.6-0.60.20.50.5
Bone: final moment0.60.93.11.7-1.5-1.81.4-0.91.21.10.90.8-0.6-0.90.70.8-0.7-0.3-0.3-0.6-0.60.20.50.5
Food consumed during 24 hour testing period3.54.25.81.4-2.0-1.51.5-2.42.12.02.12.0-2.2-1.92.22.2-1.6-2.3-2.3-2.4-2.42.4-2.2-1.6
Glucose1.01.42.3-1.11.41.4-1.51.3-1.0-0.9-1.2-1.41.11.3-1.2-1.11.51.21.21.01.0-0.61.41.0
Heart weight0.10.10.8-0.20.30.1-0.40.00.10.30.1-0.2-0.20.20.00.00.40.00.0-0.1-0.10.70.20.9
Delay discount hyperbolic model param0.10.10.4-0.20.40.6-0.60.2-0.3-0.7-0.4-0.40.30.4-0.3-0.30.60.30.30.20.2-0.10.10.4
Intermittent access intake day 1-15 change0.20.21.00.4-0.5-0.1-0.0-0.60.70.10.30.3-0.5-0.60.30.4-0.1-0.4-0.4-0.4-0.41.0-0.3-1.0
Intermittent access intake escalation0.10.10.40.0-0.20.2-0.3-0.30.3-0.2-0.1-0.0-0.2-0.2-0.00.00.2-0.1-0.1-0.0-0.00.5-0.1-0.6
Intermittent access intake escalation 20.50.51.50.7-0.8-0.50.4-0.70.90.40.60.6-0.7-0.80.60.6-0.3-0.7-0.7-0.6-0.61.0-0.6-1.2
Intermitt. access day 1 inactive lever presses4.64.97.62.7-2.5-2.52.8-2.42.42.42.32.5-2.3-2.32.12.2-2.5-2.1-2.1-1.9-1.91.8-1.1-0.8
Intermitt. access day 15 inactive lever presses2.93.25.52.2-1.4-2.31.9-1.92.01.12.01.8-1.6-1.61.91.9-1.5-1.9-1.9-1.6-1.61.7-2.1-1.2
Intermitt. access escalation Index3.83.36.2-1.81.42.1-1.82.1-1.8-1.2-2.0-1.91.81.6-2.0-1.91.71.81.81.81.8-1.62.51.5
Intermittent access day 1 total infusions0.81.01.60.9-0.9-1.20.9-1.01.11.31.10.9-1.2-0.81.11.1-0.8-0.8-0.8-1.1-1.11.1-0.60.1
Intermittent access day 15 total infusions0.60.71.70.5-0.8-0.60.4-1.01.00.80.80.7-1.1-0.70.90.8-0.4-0.8-0.8-0.9-0.91.3-0.8-0.3
Intermittent access terminal intake (last 3 days)2.62.93.91.5-1.6-1.61.5-1.81.91.71.81.7-1.9-1.71.81.8-1.5-1.7-1.7-1.8-1.82.0-1.5-1.0
Intermittent access total infusions3.03.44.41.7-2.0-1.81.7-2.12.02.01.91.9-2.1-1.81.91.9-1.7-1.8-1.8-1.9-1.91.9-1.4-0.6
Intermittent access day 1 locomotion3.94.15.72.1-2.2-2.42.0-2.32.42.22.32.0-2.3-1.92.22.1-1.7-1.8-1.8-2.0-2.02.2-1.4-0.9
Intermittent access day 15 total locomotion5.25.68.82.2-3.0-2.32.3-2.72.62.42.42.4-2.6-2.32.42.4-2.3-2.4-2.4-2.3-2.32.5-1.8-1.4
Intermittent access total locomotion8.19.312.63.0-3.5-3.33.1-3.63.43.03.23.1-3.2-2.93.23.1-2.8-2.9-2.9-3.0-3.03.1-2.5-1.5
Intermittent access standard deviation1.51.62.41.4-1.2-1.41.1-1.51.50.81.31.2-1.3-1.11.31.3-1.0-1.2-1.2-1.2-1.21.4-1.5-0.6
Left kidney weight0.61.89.3-1.00.80.7-1.10.7-1.0-0.9-1.2-1.31.21.6-1.2-1.21.51.21.21.41.4-0.81.43.0
Right kidney weight0.30.85.0-0.4-0.20.3-0.40.5-0.5-0.5-0.9-0.80.81.0-0.9-0.81.00.90.90.90.9-0.81.42.2
Cocaine induced anxiety0.20.20.70.30.4-0.5-0.20.2-0.0-0.5-0.1-0.50.50.5-0.2-0.30.80.50.50.30.3-0.30.30.8
Post-drug Anxiety0.30.31.30.10.7-0.3-0.50.5-0.1-0.7-0.3-0.70.80.6-0.4-0.51.10.70.70.50.5-0.30.60.4
Baseline Anxiety0.90.91.4-0.91.00.8-1.01.0-0.9-1.0-1.0-1.11.01.0-1.0-1.01.21.01.01.01.0-0.80.80.5
Tail length2.37.18.32.6-2.8-2.72.9-2.62.72.82.82.8-2.9-2.72.82.8-2.6-2.6-2.6-2.8-2.82.3-2.1-1.7
Length with tail1.96.812.12.7-3.5-2.63.0-2.42.83.12.52.7-2.7-3.02.52.8-2.7-2.4-2.4-2.6-2.62.0-0.8-1.9
Length without tail0.30.62.61.0-1.6-0.61.0-0.40.80.90.40.7-0.5-1.10.30.7-0.7-0.4-0.4-0.3-0.30.00.8-1.0
Times rat made contact with spout0.70.81.71.0-1.3-1.00.9-1.01.10.90.90.9-1.0-0.70.90.9-0.8-0.8-0.8-0.9-0.91.0-0.4-0.8
Lifetime Intake3.64.15.32.0-2.0-2.12.1-2.32.12.22.22.1-2.3-1.92.22.2-2.0-2.0-2.0-2.2-2.22.0-1.7-0.3
Liver weight, left0.81.32.91.1-1.6-0.91.5-0.80.81.71.11.2-1.1-1.31.01.2-1.6-0.9-0.9-1.2-1.20.00.0-0.8
Liver weight, right0.50.82.1-0.60.30.2-0.30.8-0.9-0.4-0.8-0.81.10.9-0.9-0.90.81.01.01.01.0-1.51.11.2
Locomotor activity0.50.92.20.7-1.5-0.50.9-1.40.80.90.80.9-1.1-0.60.80.8-0.6-1.0-1.0-0.8-0.80.8-0.41.4
Locomotor testing distance1.72.85.81.6-1.8-1.41.5-2.41.71.51.81.7-2.0-1.31.71.6-1.4-1.9-1.9-1.7-1.72.0-1.50.6
Locomotor testing rearing1.32.04.81.3-1.6-0.91.0-2.21.50.91.41.4-1.7-1.11.51.2-1.0-1.8-1.8-1.4-1.42.0-1.4-0.0
Locomotion in novel chamber0.30.32.9-0.0-0.70.2-0.20.20.00.0-0.6-0.50.30.1-0.6-0.60.30.40.40.70.70.01.70.1
Locomotion in novel chamber post-restriction1.92.24.51.6-1.3-1.71.7-0.91.52.11.61.5-1.6-1.81.61.6-1.8-1.0-1.0-1.6-1.61.0-0.3-1.4
Fecal boli incidents, locomotor time 10.10.11.0-0.10.50.1-0.20.20.10.30.10.0-0.3-0.40.10.20.1-0.1-0.1-0.1-0.10.50.1-1.0
Change in fecal boli incidents, locomotor task0.20.20.6-0.60.60.2-0.60.4-0.3-0.5-0.3-0.40.50.8-0.4-0.40.6-0.1-0.10.60.6-0.0-0.40.1
Time >=10cm from walls, locomotor time 13.33.36.3-1.61.31.9-1.82.1-1.7-1.5-1.9-2.01.71.8-2.0-1.91.61.91.91.91.9-1.52.51.8
Bouts of movement, locomotor time 10.20.30.9-0.60.80.3-0.60.2-0.5-1.0-0.4-0.50.70.6-0.3-0.40.50.40.40.30.3-0.4-0.60.1
Total resting periods, locomotor time 10.30.41.1-0.60.80.3-0.70.4-0.6-1.0-0.5-0.60.90.7-0.5-0.50.70.50.50.50.5-0.6-0.5-0.1
Rest time, locomotor task time 10.20.20.8-0.10.80.1-0.00.9-0.5-0.4-0.3-0.20.50.2-0.3-0.30.20.30.30.40.4-0.90.0-0.7
Distance moved, locomotor task time 10.50.51.80.6-1.3-0.60.6-1.40.90.50.60.7-0.6-0.70.60.6-0.8-0.6-0.6-0.6-0.60.9-0.6-0.0
Vertical activity count, locomotor time 10.30.31.20.6-1.1-0.60.6-0.90.70.40.30.4-0.3-0.40.30.4-0.6-0.3-0.3-0.3-0.30.60.10.4
Time >=10cm from walls, locomotor time 20.30.31.50.3-0.10.1-0.50.6-0.2-0.6-0.4-0.70.50.4-0.5-0.60.70.80.80.60.6-0.41.20.4
Bouts of movement, locomotor time 20.20.21.6-0.41.30.3-0.70.3-0.4-0.8-0.3-0.40.30.6-0.2-0.20.40.20.20.30.30.0-0.60.1
Total resting periods, locomotor time 20.50.52.4-0.71.50.6-0.90.6-0.7-1.1-0.6-0.70.60.8-0.6-0.60.70.50.50.60.6-0.3-0.30.3
Rest time, locomotor task time 23.54.09.3-2.13.11.9-2.12.8-2.2-1.8-1.9-2.01.91.9-1.9-2.01.92.02.01.81.8-1.81.40.6
Distance moved, locomotor task time 20.50.52.51.0-1.6-0.70.7-1.40.90.20.60.6-0.3-0.60.60.6-0.8-0.4-0.4-0.5-0.50.5-0.40.1
Vertical activity count, locomotor time 23.03.36.22.3-2.3-2.02.0-2.52.01.31.91.9-1.6-1.81.91.9-1.8-1.5-1.5-1.7-1.71.5-1.6-0.6
Light reinforcement 10.50.93.60.50.1-0.91.0-0.80.30.81.21.1-0.7-0.81.11.2-1.0-1.1-1.1-1.2-1.20.1-1.90.1
Light reinforcement 20.81.12.81.0-0.2-1.41.3-0.80.61.01.31.2-0.8-1.01.11.1-1.2-0.9-0.9-0.9-0.90.0-1.7-0.7
Bone: marrow area13.930.237.36.1-6.1-5.75.9-5.56.16.05.75.7-5.8-6.05.55.3-5.6-5.3-5.3-5.1-5.15.4-2.7-4.3
Bone: maximum diameter4.88.815.23.9-3.3-3.93.5-2.93.43.53.03.0-2.9-3.33.03.0-2.7-2.5-2.5-2.6-2.62.5-0.8-1.4
Bone: maximum force1.42.45.62.0-1.9-2.42.0-1.71.81.91.61.6-1.4-1.61.51.5-1.2-1.2-1.2-1.4-1.41.2-0.50.1
Bone: maximum moment1.52.56.02.2-1.9-2.42.0-1.71.91.81.71.6-1.4-1.61.51.6-1.2-1.2-1.2-1.3-1.31.2-0.5-0.0
Mean time between licks in bursts0.10.10.8-0.10.0-0.2-0.1-0.40.40.50.30.1-0.4-0.30.30.30.1-0.3-0.3-0.3-0.30.9-0.2-0.5
Mean num. licks in bursts0.50.51.90.4-0.5-0.70.5-1.10.60.30.70.7-0.5-0.50.70.6-0.6-0.9-0.9-0.7-0.70.8-1.4-0.9
Cd content in liver3.43.76.8-2.62.02.6-2.21.8-2.2-1.9-2.1-2.01.91.7-2.0-2.31.61.81.81.91.9-1.51.00.1
Co content in liver0.40.52.4-1.10.41.6-1.10.5-0.7-0.7-0.8-0.70.50.5-0.7-0.60.50.50.50.50.5-0.30.3-0.3
Cu content in liver0.40.51.20.8-0.3-0.90.7-0.40.60.40.80.7-0.5-0.70.80.8-0.7-0.8-0.8-0.8-0.80.3-1.1-1.0
Fe content in liver0.20.30.7-0.40.80.6-0.10.7-0.7-0.5-0.5-0.20.40.5-0.4-0.6-0.10.40.40.40.4-0.70.30.6
K content in liver1.01.02.41.0-1.1-0.61.4-0.20.71.60.91.1-1.0-1.50.81.2-1.6-0.8-0.8-1.0-1.0-0.10.2-1.0
Mg content in liver0.30.31.50.0-0.00.20.60.6-0.30.60.30.6-0.2-0.70.30.6-1.1-0.2-0.2-0.7-0.7-1.0-0.3-1.2
Mn content in liver0.30.32.20.3-0.3-0.21.00.6-0.40.6-0.00.40.2-0.4-0.20.1-0.90.10.10.10.1-1.50.80.2
Na content in liver0.60.62.10.8-0.5-0.21.0-0.10.41.20.70.9-0.9-0.90.70.9-1.5-0.5-0.5-1.0-1.0-0.20.3-0.1
Rb content in liver3.03.86.7-2.01.92.2-1.52.5-2.4-1.5-2.1-1.82.01.7-2.1-1.91.21.91.91.81.8-2.61.81.2
Se content in liver1.11.32.7-1.61.21.6-1.11.5-1.5-0.7-1.2-1.11.01.0-1.2-1.10.71.01.01.11.1-1.21.00.6
Sr content in liver0.30.30.80.9-0.9-0.90.5-0.70.80.50.60.3-0.4-0.30.40.4-0.0-0.2-0.2-0.3-0.30.50.20.3
Zn content in liver0.10.20.80.4-0.6-0.30.50.30.00.90.30.2-0.1-0.20.10.3-0.50.00.0-0.2-0.2-0.50.80.0
Bone: minimum diameter13.224.731.15.4-5.4-5.45.1-5.35.65.45.25.0-5.2-5.25.15.1-4.6-4.8-4.8-4.9-4.94.9-2.8-3.2
Time in familiar zone, hab. session 11.00.92.50.0-0.6-0.00.5-0.70.70.90.60.9-1.0-0.90.90.9-1.0-1.2-1.2-1.1-1.11.3-1.1-1.6
Time in novel zone, hab. session 11.51.43.1-0.31.10.2-0.90.9-1.0-1.4-0.9-1.21.31.4-1.1-1.21.41.41.41.41.4-1.31.01.8
Total zone transitions, hab. session 10.10.20.9-0.0-0.9-0.00.3-0.90.40.40.20.3-0.4-0.10.30.4-0.0-0.5-0.5-0.3-0.30.6-0.40.5
Total locomotion distance, hab. session 10.60.83.01.1-1.7-1.21.3-1.41.00.70.80.9-0.6-0.60.80.8-0.5-0.8-0.8-0.6-0.60.5-0.60.6
Locomotion velocity, hab. session 10.91.34.11.2-2.0-1.31.5-1.61.21.11.11.2-0.9-1.01.01.1-0.9-1.1-1.1-0.8-0.80.7-0.70.1
Time in familiar zone, hab. session 21.41.42.30.5-1.2-0.20.8-1.21.11.31.01.2-1.5-1.31.11.0-1.4-1.4-1.4-1.4-1.41.5-0.8-1.1
Time in novel zone, hab. session 21.51.52.5-0.31.2-0.1-0.71.2-1.0-1.3-1.0-1.21.61.3-1.1-1.11.41.51.51.51.5-1.60.91.2
Total zone transitions, hab. session 20.10.10.3-0.3-0.50.40.1-0.60.00.20.00.2-0.4-0.10.10.3-0.2-0.4-0.4-0.3-0.30.2-0.30.5
Total locomotion distance, hab. session 20.50.61.80.2-0.9-0.41.0-1.10.40.70.70.9-0.7-0.60.80.8-0.9-1.0-1.0-0.8-0.80.2-1.3-0.0
Locomotion velocity, hab. session 20.40.51.50.1-0.9-0.40.9-1.00.40.70.60.9-0.6-0.60.70.8-0.8-1.0-1.0-0.7-0.70.2-1.2-0.1
Novel to familiar place preference ratio0.30.30.70.8-0.5-0.80.4-0.80.70.60.70.4-0.4-0.50.60.6-0.2-0.5-0.5-0.5-0.50.6-0.3-0.0
Novelty place preference0.10.10.30.6-0.3-0.60.2-0.60.40.30.40.2-0.2-0.30.30.3-0.0-0.3-0.3-0.3-0.30.3-0.00.2
Time in novel zone, NPP test0.10.10.30.5-0.2-0.50.2-0.50.30.20.30.1-0.0-0.10.20.10.1-0.1-0.1-0.1-0.10.20.20.5
Total zone transitions, NPP test0.10.10.9-0.2-0.60.10.5-0.4-0.10.40.00.3-0.2-0.00.00.2-0.2-0.2-0.20.00.0-0.3-0.10.9
Total locomotion distance, NPP test0.40.62.20.7-1.5-0.91.3-1.20.60.70.60.9-0.5-0.70.60.7-0.7-0.7-0.7-0.4-0.40.1-0.70.2
Locomotion velocity, NPP test0.40.61.50.3-1.0-0.71.1-1.20.50.80.70.9-0.6-0.60.70.8-0.7-0.9-0.9-0.6-0.60.3-1.20.1
Intraocular pressure1.01.44.50.6-0.1-1.10.4-1.61.30.81.20.9-1.2-0.81.31.2-0.2-1.4-1.4-1.3-1.32.1-2.0-0.5
Delta distance traveled before/after self-admin0.30.31.3-0.50.50.6-0.40.2-0.5-0.7-0.5-0.40.50.6-0.6-0.60.30.40.40.70.7-0.30.21.1
Delta ambulatory time before/after self-admin0.00.00.2-0.0-0.10.10.3-0.2-0.0-0.10.00.20.0-0.0-0.1-0.1-0.5-0.2-0.20.20.2-0.1-0.20.2
Parametrial fat weight1.02.04.01.7-1.8-2.01.7-0.91.51.41.61.3-1.1-1.41.51.5-1.2-1.1-1.1-1.4-1.40.5-0.9-1.5
Pavlov. Cond. lever latency1.82.35.2-2.32.11.9-2.01.6-1.8-1.4-1.6-1.61.31.6-1.4-1.71.51.11.11.21.2-0.80.4-0.1
Pavlov. Cond. magazine entry latency3.64.67.72.8-2.5-2.52.7-2.12.32.22.32.3-2.1-2.42.12.4-2.3-1.9-1.9-2.0-2.01.3-1.1-0.9
Pavlov. Cond. change in total contacts3.03.26.32.5-2.0-2.12.1-1.92.01.62.01.9-1.7-1.81.82.2-1.9-1.5-1.5-1.7-1.71.0-1.1-0.5
Pavlov. Cond. index score3.03.87.02.6-2.3-2.32.4-2.02.12.02.22.1-1.9-2.11.92.2-2.2-1.6-1.6-1.8-1.81.1-0.8-0.4
Pavlov. Cond. latency score2.43.15.52.3-2.2-2.02.1-1.81.91.81.91.9-1.8-1.91.72.0-2.0-1.4-1.4-1.6-1.61.0-0.6-0.2
Pavlov. Cond. lever contacts1.61.94.12.0-1.8-1.61.6-1.61.71.11.51.4-1.3-1.51.31.6-1.3-1.0-1.0-1.2-1.20.9-0.5-0.3
Pavlov. Cond. magazine entry number2.83.56.5-2.52.02.3-2.41.7-1.9-1.9-2.1-2.11.82.1-1.9-2.12.21.51.51.71.7-0.81.00.7
Pavlov. Cond. intertrial magazine entries1.41.73.20.3-0.6-0.61.0-1.41.01.61.21.4-1.5-1.21.31.4-1.4-1.8-1.8-1.3-1.31.6-1.8-0.8
Pavlov. Cond. lever-magazine prob. diff.2.73.36.72.6-2.1-2.32.3-1.82.11.82.01.9-1.8-2.01.82.1-2.0-1.4-1.4-1.6-1.61.1-0.7-0.3
Pavlov. Cond. response bias3.34.09.33.1-2.4-2.72.7-1.92.21.92.32.2-1.8-2.21.92.2-2.1-1.5-1.5-1.6-1.60.9-0.8-0.6
Pavlov. Cond. lever latency0.30.40.8-0.80.70.6-0.80.5-0.6-0.9-0.7-0.70.70.7-0.6-0.60.70.50.50.60.6-0.4-0.1-0.2
Pavlov. Cond. magazine entry latency2.93.45.3-1.71.62.1-1.92.1-1.8-1.5-2.0-1.91.71.7-2.0-1.81.71.81.81.81.8-1.62.31.4
Pavlov. Cond. change in total contacts0.30.51.20.5-0.8-0.10.8-0.50.51.00.60.8-0.8-0.80.60.6-1.1-0.7-0.7-0.8-0.80.50.0-0.4
Pavlov. Cond. index score0.10.11.20.0-0.00.3-0.10.3-0.10.1-0.3-0.20.10.1-0.3-0.30.10.20.20.30.3-0.11.10.6
Pavlov. Cond. latency score0.20.21.80.00.00.3-0.20.4-0.2-0.0-0.4-0.40.20.2-0.5-0.40.30.40.40.50.5-0.21.30.9
Pavlov. Cond. lever contacts0.20.30.60.7-0.6-0.60.7-0.60.50.70.60.6-0.5-0.60.50.4-0.7-0.5-0.5-0.5-0.50.3-0.10.1
Pavlov. Cond. magazine entry number3.74.56.81.9-1.7-2.22.1-2.32.11.82.32.2-2.1-2.12.32.2-2.0-2.1-2.1-2.2-2.21.9-2.6-1.9
Pavlov. Cond. intertrial magazine entries15.420.223.44.2-3.9-4.54.4-4.54.64.34.84.6-4.6-4.64.84.8-4.3-4.6-4.6-4.7-4.74.2-4.5-4.2
Pavlov. Cond. lever-magazine prob. diff.0.10.21.5-0.10.10.4-0.20.5-0.30.0-0.4-0.30.20.2-0.4-0.40.20.40.40.40.4-0.31.20.7
Pavlov. Cond. response bias0.00.00.30.1-0.10.00.20.0-0.10.3-0.00.10.00.0-0.1-0.1-0.20.10.10.10.1-0.10.50.4
Time in closed arm before self-admin1.31.53.5-0.70.80.9-1.00.9-1.1-1.4-1.1-1.21.21.3-1.2-1.31.21.31.31.31.3-1.31.11.9
Time in closed arm after self-admin1.61.64.1-0.9-0.01.4-0.91.1-1.1-1.2-1.4-1.31.31.0-1.5-1.51.01.41.41.51.5-1.42.00.7
Time in open arm before self-admin0.60.71.9-0.50.30.7-1.00.5-0.4-0.7-0.9-1.00.80.6-1.0-0.91.11.01.01.01.0-0.11.40.3
Time in open arm after self-admin0.40.41.50.10.5-0.4-0.1-0.50.50.50.60.4-0.7-0.40.70.7-0.1-0.7-0.7-0.7-0.71.2-1.2-0.8
Bone: periosteal estimation9.519.629.75.4-4.9-5.45.0-4.65.04.84.74.6-4.5-4.74.54.5-4.2-4.0-4.0-4.1-4.14.0-2.1-2.4
Bone: periosteal perimeter4.88.114.63.8-3.5-3.73.2-3.03.53.42.92.7-2.9-3.22.72.8-2.4-2.3-2.3-2.4-2.42.6-0.3-1.1
Bone: post-yield work2.12.84.41.8-2.1-1.81.6-1.92.12.01.61.6-1.8-1.91.61.6-1.2-1.6-1.6-1.6-1.62.1-0.5-1.2
Progressive ratio test 1 active lever presses5.05.26.92.3-2.4-2.42.5-2.52.42.62.42.4-2.5-2.22.32.3-2.4-2.3-2.3-2.3-2.32.1-1.5-0.6
Progressive ratio test 1 breakpoint6.77.08.72.6-2.6-2.72.8-2.92.72.92.82.8-2.9-2.62.82.8-2.7-2.7-2.7-2.7-2.72.5-2.0-0.9
Progressive ratio test 1 inactive lever presses5.15.68.02.4-2.3-2.42.6-2.62.42.82.52.6-2.7-2.32.52.5-2.5-2.4-2.4-2.4-2.42.1-1.6-0.1
Progressive ratio test 2 active lever presses5.96.37.72.5-2.6-2.82.7-2.72.72.72.72.6-2.6-2.62.62.6-2.5-2.4-2.4-2.5-2.52.4-1.9-1.4
Progressive ratio test 2 breakpoint6.77.59.32.9-2.8-3.12.8-2.93.02.93.02.8-2.9-2.82.92.8-2.6-2.6-2.6-2.8-2.82.7-1.9-1.6
Progressive ratio test 2 inactive lever presses5.36.17.52.2-2.4-2.62.5-2.72.52.62.72.6-2.5-2.42.72.6-2.4-2.5-2.5-2.6-2.62.3-2.3-1.1
Incentive Sensitization - Responses3.93.94.91.9-2.1-2.02.0-2.12.12.22.02.0-2.0-2.22.02.0-2.0-1.9-1.9-2.0-2.01.9-1.3-1.5
Incentive Sensitization - Breakpoint3.53.54.61.9-2.2-1.91.9-2.02.02.11.91.9-1.9-2.11.91.9-1.9-1.8-1.8-1.9-1.91.8-1.1-1.5
Sum of active levers in priming session hrs 5-60.20.21.0-0.61.00.7-0.50.5-0.5-0.1-0.2-0.2-0.10.1-0.0-0.1-0.10.30.3-0.4-0.4-0.2-0.2-0.0
Progressive ratio0.10.10.5-0.40.20.4-0.10.6-0.20.1-0.4-0.20.2-0.1-0.4-0.3-0.10.40.40.30.3-0.30.7-0.3
Food seeking constrained by brief footshock3.23.95.51.6-2.3-1.31.8-2.32.01.91.82.0-2.1-2.31.91.9-2.0-2.1-2.1-2.0-2.02.1-1.4-2.0
Seeking ratio, punishment vs. effort1.51.83.21.3-1.5-1.11.1-1.81.41.01.31.3-1.4-1.21.41.4-1.1-1.5-1.5-1.3-1.31.5-1.3-0.9
Retroperitoneal fat weight1.54.88.31.7-2.9-2.12.1-2.42.32.02.12.2-2.1-2.02.22.1-1.9-2.6-2.6-2.1-2.12.2-2.3-1.8
Reaction time number correct0.71.01.9-0.80.70.6-0.81.0-0.9-0.3-0.8-1.00.91.0-1.0-1.01.31.21.21.11.1-0.81.31.4
Reaction time mean minus median0.30.41.1-0.61.00.7-0.70.8-0.5-1.0-0.7-0.60.60.6-0.6-0.60.40.60.60.60.6-0.3-0.1-0.4
Reaction time mean minus median AUC1.31.62.8-1.31.61.3-1.11.7-1.4-1.3-1.4-1.21.31.3-1.3-1.30.81.41.41.31.3-1.40.90.6
Reaction time num false alarms3.04.15.72.2-2.2-2.02.2-2.12.32.42.12.1-2.3-2.22.12.2-1.9-1.7-1.7-2.2-2.22.0-0.7-0.4
Reaction time num false alarms AUC3.44.86.62.4-2.5-2.22.5-2.22.42.62.32.3-2.4-2.42.32.4-2.2-1.8-1.8-2.3-2.31.9-0.9-0.7
Reaction time trials correct on left0.71.01.9-0.80.70.6-0.81.0-0.9-0.3-0.8-1.00.91.0-1.0-1.01.31.21.21.11.1-0.81.31.4
Reaction time trials on left0.60.91.7-0.80.70.5-0.81.0-0.9-0.2-0.8-1.00.91.0-0.9-1.01.21.11.11.11.1-0.81.31.3
Reaction time mean1.01.32.2-0.91.41.1-0.71.5-1.2-1.4-1.3-1.01.31.1-1.3-1.20.51.21.21.21.2-1.50.90.3
Reaction time mean AUC1.31.72.8-1.01.61.3-0.91.7-1.4-1.6-1.5-1.11.41.2-1.4-1.30.61.41.41.31.3-1.60.90.4
Median of all reaction times1.01.32.4-0.81.31.0-0.71.5-1.3-1.3-1.3-0.91.31.0-1.3-1.20.51.21.21.21.2-1.61.00.5
Reaction time omissions0.10.10.50.40.5-0.60.40.30.0-0.30.00.10.3-0.1-0.1-0.1-0.10.30.30.30.3-0.3-0.2-0.7
Reaction time false alarm rate3.54.96.12.4-2.4-2.12.4-2.32.42.12.22.3-2.4-2.52.32.4-2.4-2.0-2.0-2.4-2.42.0-1.2-1.2
Reaction time premature initiation rate1.11.52.81.2-0.7-1.71.0-1.51.21.11.51.2-1.2-0.91.41.2-1.0-1.3-1.3-1.3-1.31.3-1.6-0.5
Reaction time premature initiations0.40.61.60.7-0.4-1.20.6-0.90.71.01.10.7-0.8-0.40.90.7-0.4-0.7-0.7-0.7-0.70.8-0.90.0
Std. dev. reaction times0.50.71.3-0.71.10.8-0.61.1-0.8-1.2-0.9-0.70.90.7-0.8-0.80.30.90.90.80.8-0.90.2-0.6
Reaction time trials completed0.60.91.7-0.80.70.5-0.81.0-0.9-0.2-0.8-1.00.91.0-0.9-1.01.21.11.11.11.1-0.81.31.3
Reaction time trials AUC0.71.01.7-0.90.70.6-0.81.0-0.9-0.3-0.9-1.00.91.0-1.0-1.01.21.11.11.11.1-0.81.21.3
Run reversals in cocaine runway, females0.40.41.8-0.40.50.2-0.90.3-0.1-1.3-0.5-0.80.60.8-0.5-0.51.20.50.50.60.60.2-0.6-0.2
Run reversals in cocaine runway, males0.10.10.5-0.00.4-0.0-0.40.3-0.1-0.2-0.3-0.50.30.2-0.4-0.40.60.50.50.50.50.00.70.0
Latency to leave start box in cocaine runway0.40.40.9-0.40.70.4-0.70.7-0.5-0.6-0.6-0.80.60.7-0.6-0.71.00.70.70.70.7-0.40.80.5
Latency to leave start box in cocaine runway, F1.11.22.4-0.50.90.6-1.10.8-0.7-1.0-1.0-1.21.01.1-1.1-1.11.51.31.31.21.2-0.61.51.4
Latency to leave start box in cocaine runway, M0.10.10.6-0.20.00.1-0.00.3-0.2-0.10.10.1-0.10.00.10.1-0.1-0.2-0.2-0.2-0.2-0.3-0.5-0.8
Std. dev. time between licks in bursts0.00.10.5-0.20.40.1-0.2-0.30.0-0.10.10.1-0.2-0.10.20.1-0.00.10.1-0.2-0.20.3-0.7-0.1
Total sessions with >9 infusions0.30.41.70.2-0.4-0.50.6-0.70.30.70.60.6-0.7-0.20.50.6-0.7-0.5-0.5-0.6-0.60.4-0.61.3
Short access day 1 total inactive lever presses0.80.92.01.3-1.4-1.21.0-1.21.20.91.00.8-1.0-0.70.90.9-0.6-0.7-0.7-0.8-0.80.9-0.20.7
Short access day 10 total inactive lever presses0.90.91.90.8-0.3-0.80.8-1.10.90.81.11.0-1.0-1.01.01.1-0.7-1.0-1.0-1.0-1.01.0-1.4-0.9
Short access day 1 total infusions1.31.41.90.9-0.9-1.11.2-1.31.01.41.31.3-1.4-0.81.31.3-1.2-1.1-1.1-1.3-1.31.0-1.11.1
Short access day 10 total infusions6.67.48.92.7-2.4-2.82.6-3.02.92.73.02.8-3.0-2.63.03.0-2.5-2.7-2.7-2.9-2.92.8-2.5-0.9
Short access total infusions3.74.25.42.1-1.8-2.12.1-2.32.12.12.32.2-2.3-1.82.22.2-2.1-2.0-2.0-2.2-2.22.0-1.70.3
Short access day 1 locomotion4.14.45.61.9-1.6-2.31.9-2.32.22.12.32.1-2.3-1.82.42.2-1.8-2.0-2.0-2.3-2.32.3-2.2-0.5
Short access day 10 total locomotion11.512.917.73.4-3.7-3.53.4-4.23.93.43.83.7-3.8-3.63.83.7-3.4-3.5-3.5-3.7-3.73.7-3.4-2.4
Short access total locomotion5.86.19.52.3-2.4-2.52.2-3.12.72.32.62.5-2.8-2.22.72.6-2.3-2.4-2.4-2.6-2.62.8-2.4-0.7
One hour access (0.3 mA shock)1.11.32.11.1-1.1-1.01.0-1.21.31.31.11.1-1.5-1.21.21.2-1.0-1.1-1.1-1.2-1.21.4-0.6-0.6
Compulsive drug intake1.51.53.8-0.80.60.9-1.01.2-1.0-0.9-1.3-1.41.41.1-1.4-1.31.41.31.31.41.4-1.22.01.1
One hour access (shock baseline)1.82.03.01.1-1.2-1.11.2-1.61.41.41.41.5-1.7-1.41.51.5-1.5-1.5-1.5-1.6-1.61.6-1.6-0.9
Social response proportion0.30.30.9-0.60.60.5-0.90.4-0.2-0.4-0.5-0.70.20.5-0.5-0.40.90.50.50.50.50.40.40.2
Social responses0.10.10.40.1-0.30.00.0-0.40.30.30.20.1-0.3-0.20.30.30.0-0.2-0.2-0.4-0.40.5-0.00.6
Social time0.10.21.30.5-0.0-0.5-0.1-0.00.70.30.40.0-0.4-0.20.20.20.4-0.3-0.30.10.11.10.1-0.5
Soleus weight0.10.40.80.8-0.5-0.90.4-0.70.80.70.50.4-0.7-0.20.60.7-0.3-0.5-0.5-0.6-0.60.90.10.7
Bone: stiffness0.61.03.00.8-1.2-0.91.3-0.90.91.70.91.1-1.1-1.20.90.9-1.1-1.0-1.0-1.0-1.00.70.1-0.1
Tibialis anterior weight0.41.36.0-0.3-0.00.0-0.4-1.20.80.10.90.6-1.1-0.41.11.2-0.3-1.4-1.4-1.4-1.41.7-2.4-1.6
Time to tail flick, vehicle, before self-admin0.40.42.90.20.0-0.1-0.21.1-0.1-0.1-0.5-0.60.50.2-0.7-0.60.60.80.80.90.9-0.51.7-0.4
Time to tail flick, vehicle, after self-admin0.91.02.10.9-0.4-1.31.1-0.60.81.41.21.0-1.0-1.11.11.1-1.0-0.9-0.9-1.0-1.00.6-0.7-1.2
Time to tail flick, test, before self-admin0.80.71.3-0.90.60.9-1.10.9-0.7-1.1-1.0-1.00.90.8-1.0-1.01.10.70.71.01.0-0.40.6-0.4
Time to tail flick, test, after self-admin0.10.10.2-0.10.3-0.0-0.20.5-0.3-0.2-0.3-0.30.40.2-0.3-0.30.30.30.30.40.4-0.40.40.1
Delta time to tail flick, vehicle, before/after SA3.03.05.51.3-1.0-1.61.8-1.71.31.61.91.9-1.6-1.71.91.9-1.8-1.8-1.8-2.0-2.01.0-2.4-1.4
Delta time to tail flick, test, before/after SA0.10.10.20.10.1-0.10.40.2-0.10.50.20.2-0.2-0.30.10.2-0.40.00.0-0.2-0.2-0.50.20.2
Tibia length0.10.31.90.1-0.8-0.10.30.1-0.10.2-0.4-0.30.40.4-0.5-0.40.50.30.30.50.5-0.61.41.3
Ambulatory time before self-admin0.40.43.10.10.20.2-0.60.60.00.1-0.4-0.60.10.2-0.4-0.30.80.80.80.40.40.21.81.0
Ambulatory time after self-admin0.10.11.10.5-0.1-0.00.00.00.40.30.0-0.0-0.3-0.1-0.1-0.10.10.20.20.30.30.51.10.7
Bone: tissue strength1.41.42.1-1.20.81.1-0.91.3-1.2-0.7-1.4-1.11.21.2-1.3-1.21.11.21.21.31.3-1.11.41.3
Total heroin consumption0.40.41.31.1-0.7-0.81.0-0.20.70.90.60.7-0.7-0.70.50.6-0.8-0.5-0.5-0.5-0.50.30.60.1
Bone: trabecular number2.03.18.12.7-2.2-2.82.8-1.31.82.01.81.9-1.3-1.81.61.7-2.0-1.1-1.1-1.3-1.30.3-0.3-0.5
Bone: trabecular spacing0.60.73.3-1.61.01.8-1.50.4-0.8-0.7-0.9-0.90.30.6-0.7-0.70.80.40.40.40.40.10.1-0.2
Bone: trabecular thickness2.73.29.92.9-2.0-3.22.4-1.62.11.62.11.8-1.3-1.71.81.9-1.4-1.2-1.2-1.4-1.40.9-0.9-1.1
Bone: trabecular tissue density1.01.42.3-1.01.20.5-0.71.1-1.3-0.8-1.1-1.11.41.5-1.3-1.31.31.21.21.51.5-1.40.81.4
Water consumed over 24 hours0.10.10.30.2-0.5-0.40.3-0.30.30.00.20.2-0.10.10.20.2-0.0-0.2-0.2-0.2-0.20.1-0.30.2
Number of responses in last shaping day0.91.02.11.4-0.9-1.50.9-1.21.40.81.10.8-1.2-0.81.01.0-0.6-0.7-0.7-0.8-0.81.4-0.40.3