Hub : Genes

Stap2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Stap2 0.06 0.04 5.5e-06 0.02 0.03 0.05 0.03 5.3e-03 1.3e-04 1.9e-06 2.9e-04
2 PL mRNA stability Stap2 0.02 0.02 7.6e-03 0.01 0.01 0.01 0.01 5.6e-02 2.2e-02 3.1e-02 3.4e-02
3 Liver gene expression Stap2 0.28 0.14 0.0e+00 0.15 0.21 0.21 0.2 3.7e-16 2.1e-22 1.3e-22 1.9e-21
4 BLA mRNA stability Stap2 0.06 0.04 3.2e-03 0.03 0.04 0.03 0.04 1.4e-02 2.7e-03 9.8e-03 3.2e-03
5 BLA gene expression Stap2 0.07 0.05 6.8e-04 0.06 0.05 0.05 0.05 4.4e-04 1.4e-03 1.7e-03 1.8e-03
6 NAcc gene expression Stap2 0.03 0.02 6.0e-04 0.03 0.03 0.03 0.03 2.2e-04 1.6e-04 3.1e-04 3.9e-04
7 PL gene expression Stap2 0.02 0.02 4.0e-03 0.02 0.02 0.02 0.02 5.9e-03 1.9e-03 4.8e-03 4.3e-03
8 Liver intron excision ratio chr9_831075_831437 0.06 0.04 6.4e-06 0.04 0.04 0.04 0.04 2.7e-05 4.4e-05 3.5e-05 6.8e-05
9 Liver intron excision ratio chr9_831571_831851 0.08 0.06 1.6e-07 0.05 0.05 0.05 0.05 2.1e-06 2.4e-06 2.3e-06 4.1e-06
10 Liver mRNA stability Stap2 0.02 0.02 5.6e-03 0.01 0.01 0 0.01 1.6e-02 3.6e-02 1.2e-01 5.6e-02
11 pVTA isoform ratio XM_039083945.1 0.15 0.11 1.5e-03 0.07 0.07 0.06 0.06 5.0e-04 8.5e-04 8.6e-04 1.6e-03
12 Brain mRNA stability Stap2 0.04 0.03 5.2e-04 0.03 0.03 0.04 0.03 3.6e-04 8.7e-04 7.4e-05 9.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.10.30.50.10.00.2-0.30.40.50.3-0.3-0.3-0.2-0.1
Area under the delay curve3.13.38.72.8-2.02.4-1.81.3-1.1-0.6-1.31.31.3-3.01.4
BMI with tail2.68.310.7-0.53.1-2.83.2-3.23.23.03.1-3.1-3.11.5-3.3
BMI without tail2.04.16.7-2.62.3-2.32.2-2.01.81.51.9-1.9-1.91.9-2.1
Body weight0.31.12.30.00.9-0.61.0-1.21.41.51.1-1.1-1.1-0.4-1.2
Weight adjusted by age0.10.10.20.0-0.40.4-0.40.2-0.3-0.2-0.40.40.4-0.20.5
Bone surface0.10.20.80.90.3-0.20.3-0.50.50.60.5-0.5-0.5-0.0-0.4
Bone volume0.50.81.10.80.8-0.70.9-1.01.01.01.0-1.0-1.00.4-0.9
Breakpoint value in progressive ratio session2.12.314.93.90.50.00.7-1.11.31.71.1-1.1-1.1-1.0-1.0
Number of licking bursts2.32.73.7-0.31.9-1.91.8-1.71.61.41.7-1.7-1.71.5-1.6
Context. condit. distance diff. score0.40.42.0-0.30.7-0.90.6-0.50.40.20.5-0.5-0.51.4-0.3
Locomotion velocity, session 11.21.22.2-0.51.3-1.51.2-1.01.00.71.1-1.1-1.11.3-1.1
Locomotion distance, session 10.70.91.20.01.1-1.11.0-1.00.90.81.0-1.0-1.01.1-0.9
Locomotion velocity, session 20.10.20.30.40.4-0.50.4-0.30.30.20.4-0.4-0.40.4-0.3
Locomotion distance, session 20.30.41.7-0.90.7-0.90.6-0.30.2-0.00.3-0.3-0.31.3-0.4
Locomotion velocity, session 31.61.85.92.40.8-0.41.0-1.31.41.71.4-1.4-1.4-0.6-1.1
Locomotion distance, session 32.02.25.42.31.0-0.61.2-1.61.71.91.5-1.5-1.5-0.3-1.4
Stereotopy head waving bouts, day 33.13.74.7-1.12.2-2.22.2-2.02.01.82.0-2.0-2.01.2-2.1
Stereotopy head waving duration, day 30.80.93.9-2.01.0-1.30.9-0.60.50.20.6-0.6-0.61.3-0.6
Locomotion velocity, session 70.10.10.2-0.4-0.1-0.0-0.20.3-0.4-0.5-0.30.30.30.40.3
Locomotion distance, session 70.40.51.21.10.5-0.30.6-0.70.80.90.7-0.7-0.70.0-0.7
Stereotopy head waving bouts, day 70.80.91.1-0.11.0-1.01.0-1.01.00.91.1-1.1-1.10.4-1.0
Stereotopy head waving duration, day 70.40.50.7-0.10.8-0.80.8-0.80.80.70.8-0.8-0.80.1-0.7
Locomotion velocity, session 80.30.41.6-0.70.6-0.90.5-0.30.20.00.4-0.4-0.41.3-0.3
Locomotion distance, session 81.21.84.1-0.01.5-1.71.5-1.31.20.91.3-1.3-1.32.0-1.1
Degree of sensitization distance0.60.62.2-1.50.8-1.10.6-0.30.2-0.10.3-0.3-0.31.3-0.4
Degree of sensitization stereotypy0.50.50.80.70.6-0.40.6-0.80.80.90.8-0.8-0.8-0.3-0.8
Conditioned locomotion2.53.04.71.0-2.02.2-1.91.7-1.6-1.3-1.71.71.7-1.91.6
Cocaine response after cond. corrected0.20.20.3-0.0-0.50.5-0.50.4-0.4-0.3-0.40.40.4-0.60.4
Cocaine response after cond. not corrected0.00.00.00.1-0.1-0.0-0.10.1-0.1-0.2-0.00.00.00.10.2
Cocaine response before conditioning0.10.20.30.50.4-0.40.4-0.40.40.40.4-0.4-0.40.5-0.4
Saline control response3.14.05.50.72.0-1.72.1-2.32.32.42.2-2.2-2.20.5-2.2
Bone: connectivity density0.10.21.31.10.00.20.1-0.30.40.60.4-0.4-0.4-0.6-0.2
Bone: cortical apparent density1.62.13.6-0.8-1.30.9-1.41.7-1.7-1.9-1.61.61.60.21.5
Bone: cortical area0.10.10.60.1-0.30.6-0.2-0.00.10.3-0.00.00.0-0.80.0
Bone: cortical porosity0.20.31.61.0-0.30.5-0.2-0.00.10.30.2-0.2-0.2-1.3-0.1
Bone: cortical porosity0.40.41.81.3-0.10.40.0-0.30.40.60.4-0.4-0.4-1.2-0.3
Bone: cortical thickness0.61.11.3-0.9-1.01.0-1.11.1-1.1-1.1-1.21.21.2-0.51.0
Bone: cortical thickness2.22.53.60.5-1.91.9-1.81.6-1.5-1.3-1.51.51.5-1.81.7
Bone: cortical tissue density1.52.03.5-0.8-1.20.8-1.41.6-1.7-1.9-1.61.61.60.31.5
Condit. Reinf. active minus inactive responses0.30.30.40.00.5-0.40.6-0.60.60.70.6-0.6-0.60.0-0.6
Condit. Reinf. active-inactive response ratio0.20.20.40.40.4-0.30.5-0.60.60.60.5-0.5-0.50.1-0.6
Condit. Reinf. active responses0.10.10.3-0.60.2-0.20.2-0.20.20.20.2-0.2-0.2-0.1-0.4
Condit. Reinf. inactive responses0.10.10.6-0.80.4-0.50.4-0.30.20.10.2-0.2-0.20.2-0.4
Incentive salience index mean0.10.20.60.1-0.40.6-0.40.3-0.2-0.1-0.30.30.3-0.80.2
Condit. Reinf. lever presses1.21.62.0-0.5-1.41.3-1.41.4-1.4-1.3-1.41.41.4-0.91.2
Condit. Reinf. active minus inactive responses0.10.10.6-0.70.1-0.30.00.1-0.2-0.3-0.10.10.10.80.1
Condit. Reinf. active-inactive response ratio0.10.10.7-0.80.3-0.40.2-0.1-0.0-0.10.0-0.0-0.00.7-0.1
Condit. Reinf. active responses0.20.31.5-1.20.3-0.50.10.1-0.2-0.4-0.10.10.11.10.0
Condit. Reinf. inactive responses0.40.51.1-0.40.8-0.90.8-0.70.60.40.6-0.6-0.61.0-0.7
Condit. Reinf. lever presses0.50.72.4-1.6-0.3-0.1-0.40.7-0.8-1.1-0.70.70.70.90.7
Condit. Reinf. lever reinforcers received0.20.31.6-1.20.2-0.50.10.1-0.2-0.5-0.20.20.21.10.1
Conditioned reinforcement - actives1.31.38.72.9-0.91.0-0.80.7-0.6-0.4-0.80.80.8-0.81.0
Conditioned reinforcement - inactives0.40.50.6-0.50.8-0.70.8-0.80.70.60.7-0.7-0.70.2-0.8
Conditioned locomotion2.73.34.31.9-2.02.1-1.91.8-1.6-1.4-1.81.81.8-1.71.7
Patch foraging indifference point 0 sec0.71.12.30.40.8-0.41.0-1.21.31.51.1-1.1-1.1-0.7-1.1
Patch foraging indifference point AUC2.83.24.3-0.7-1.81.7-1.91.9-2.0-1.9-2.12.12.1-0.61.9
Delay disc. indifference point, 0s delay1.01.19.13.0-0.61.0-0.50.10.00.4-0.10.10.1-1.50.3
Delay disc. indifference point, 16s delay3.13.111.13.3-1.82.3-1.61.1-0.8-0.3-1.11.11.1-2.81.2
Delay disc. indifference point, 2s delay1.11.35.21.1-1.31.6-1.10.7-0.5-0.1-0.70.70.7-2.30.7
Delay disc. indifference point, 24s delay3.02.93.90.0-2.02.0-1.91.8-1.7-1.4-1.71.71.7-1.91.7
Delay disc. indifference point, 4s delay1.41.53.81.9-1.31.5-1.20.9-0.8-0.4-0.90.90.9-1.91.0
Delay disc. indifference point, 8s delay2.42.57.72.6-1.72.1-1.51.0-0.8-0.3-1.01.01.0-2.81.1
Indifference point function ln k3.44.77.11.42.1-1.62.2-2.42.52.72.4-2.4-2.40.1-2.3
Indifference point function log k3.44.77.11.42.1-1.62.2-2.42.52.72.4-2.4-2.40.1-2.3
Patch foraging total patch changes 0 sec0.71.22.50.40.9-0.51.0-1.31.41.61.1-1.1-1.1-0.8-1.1
Patch foraging total patch changes 12 sec0.00.00.2-0.0-0.10.2-0.0-0.10.10.2-0.10.10.1-0.50.1
Patch foraging total patch changes 18 sec0.10.10.50.4-0.10.5-0.1-0.10.20.4-0.10.10.1-0.70.1
Patch foraging total patch changes 24 sec0.60.81.7-0.3-1.01.2-0.90.6-0.6-0.4-0.90.90.9-1.30.8
Patch foraging total patch changes 6 sec0.91.31.9-1.01.3-1.11.3-1.41.31.31.1-1.1-1.10.7-1.2
Patch foraging time to switch 0 sec0.40.71.00.7-0.80.7-0.90.9-0.9-0.9-0.80.80.8-0.21.0
Patch foraging water rate 0 sec1.01.62.3-0.81.2-1.01.3-1.41.51.51.4-1.4-1.4-0.1-1.4
Patch foraging water rate 12 sec2.03.14.80.41.7-1.41.8-2.02.12.22.0-2.0-2.0-0.1-2.1
Patch foraging water rate 18 sec2.73.65.60.71.8-1.42.0-2.22.32.42.1-2.1-2.1-0.0-2.2
Patch foraging water rate 24 sec1.82.64.3-0.41.5-1.11.6-1.91.92.11.8-1.8-1.8-0.3-1.8
Patch foraging water rate 6 sec7.010.215.21.03.1-2.53.3-3.63.83.93.6-3.6-3.60.3-3.4
Seeking ratio, delayed vs. immediate footshock0.50.50.70.10.8-0.80.8-0.60.70.60.8-0.8-0.80.7-0.8
Distance traveled before self-admin0.10.10.40.70.2-0.20.2-0.20.20.20.2-0.2-0.20.0-0.2
Distance traveled after self-admin0.10.10.40.60.3-0.30.4-0.40.40.40.4-0.4-0.4-0.0-0.4
Extensor digitorum longus weight0.41.62.31.21.2-0.91.3-1.41.51.51.4-1.4-1.40.7-1.2
Bone: elastic displacement2.22.54.11.7-1.92.0-1.81.5-1.3-1.0-1.31.31.3-1.81.6
Bone: elastic work0.50.74.12.0-0.71.1-0.50.2-0.00.3-0.10.10.1-1.30.4
Bone: endosteal estimation0.30.63.31.80.2-0.00.4-0.60.70.90.7-0.7-0.7-0.6-0.4
Bone: endosteal perimeter0.40.91.81.00.6-0.20.7-1.01.11.41.0-1.0-1.0-0.6-0.8
Epididymis fat weight0.51.21.60.31.2-1.21.2-1.01.21.11.2-1.2-1.20.8-1.1
Delta time in closed arm before/after self-admin2.32.33.2-0.71.7-1.81.7-1.61.41.21.6-1.6-1.61.5-1.5
Delta time in open arm before/after self-admin0.20.20.3-0.3-0.40.3-0.40.5-0.5-0.5-0.50.50.50.20.4
Diff in mean of infusions in LGA sessions0.40.43.4-1.8-0.30.2-0.30.4-0.5-0.6-0.50.50.50.40.3
Delay discount exponential model param2.82.98.0-2.21.9-2.31.8-1.31.10.61.3-1.3-1.32.8-1.3
Extinction: sum of active levers before priming0.50.51.01.00.5-0.30.6-0.70.81.00.8-0.8-0.8-0.5-0.5
Active lever presses in extinction session 60.80.72.00.90.40.00.5-0.80.91.20.7-0.7-0.7-1.4-1.0
Bone: final force0.00.00.00.00.1-0.10.1-0.10.20.20.2-0.2-0.2-0.2-0.1
Bone: final moment0.00.00.20.3-0.10.2-0.0-0.10.10.20.1-0.1-0.1-0.40.0
Food consumed during 24 hour testing period0.00.00.0-0.1-0.10.2-0.10.1-0.1-0.1-0.20.20.2-0.00.1
Glucose0.60.91.9-0.71.1-1.21.0-0.80.80.60.9-0.9-0.91.4-0.8
Heart weight1.62.23.6-1.91.6-1.81.6-1.41.31.01.4-1.4-1.41.4-1.4
Delay discount hyperbolic model param2.72.98.2-2.12.0-2.31.8-1.31.10.61.3-1.3-1.32.9-1.3
Intermittent access intake day 1-15 change1.11.17.0-2.6-0.60.3-0.70.8-0.9-1.1-0.80.80.8-0.30.8
Intermittent access intake escalation1.21.25.5-2.3-0.70.5-0.80.9-1.1-1.3-0.90.90.9-0.01.1
Intermittent access intake escalation 20.90.93.3-1.8-0.60.4-0.70.8-1.0-1.2-0.90.90.90.21.1
Intermitt. access day 1 inactive lever presses1.21.25.22.30.7-0.40.8-1.01.21.40.9-0.9-0.9-0.7-1.1
Intermitt. access day 15 inactive lever presses0.50.50.90.3-0.80.8-0.70.7-0.6-0.5-0.80.80.8-0.90.6
Intermitt. access escalation Index0.30.21.0-0.10.6-0.60.5-0.40.30.20.3-0.3-0.31.0-0.1
Intermittent access day 1 total infusions1.92.218.74.30.7-0.40.8-1.01.11.30.9-0.9-0.90.5-0.5
Intermittent access day 15 total infusions0.20.21.51.20.2-0.20.1-0.20.10.00.2-0.2-0.20.50.3
Intermittent access terminal intake (last 3 days)0.10.10.90.90.1-0.10.00.1-0.1-0.10.0-0.0-0.00.70.5
Intermittent access total infusions0.60.78.12.80.10.10.1-0.20.30.30.2-0.2-0.20.20.3
Intermittent access day 1 locomotion1.71.815.03.90.6-0.20.7-0.91.01.20.8-0.8-0.8-0.4-0.5
Intermittent access day 15 total locomotion0.10.10.30.50.2-0.20.2-0.30.20.20.3-0.3-0.30.0-0.1
Intermittent access total locomotion0.70.89.13.0-0.10.3-0.0-0.10.20.30.0-0.0-0.0-0.30.1
Intermittent access standard deviation0.80.84.4-2.1-0.40.1-0.50.6-0.9-1.1-0.60.60.60.80.8
Left kidney weight0.10.33.1-1.80.2-0.30.2-0.00.0-0.00.1-0.1-0.10.2-0.2
Right kidney weight0.10.21.7-1.30.3-0.40.3-0.20.30.20.3-0.3-0.30.2-0.3
Cocaine induced anxiety1.61.82.61.01.5-1.41.5-1.51.41.31.2-1.2-1.21.4-1.6
Post-drug Anxiety0.10.10.3-0.5-0.20.2-0.30.3-0.3-0.4-0.50.50.5-0.0-0.1
Baseline Anxiety4.64.95.6-2.2-2.32.1-2.32.4-2.3-2.2-2.32.32.3-1.92.0
Tail length0.41.36.1-2.5-0.70.4-0.81.0-1.1-1.3-1.01.01.00.41.0
Length with tail0.62.23.10.4-1.71.8-1.61.5-1.4-1.1-1.51.51.5-1.51.7
Length without tail0.30.73.92.0-0.70.9-0.60.4-0.20.0-0.40.40.4-1.40.5
Times rat made contact with spout0.10.10.10.2-0.20.1-0.20.3-0.3-0.3-0.30.30.30.40.2
Lifetime Intake1.01.212.63.50.20.00.3-0.40.50.70.4-0.4-0.4-0.00.0
Liver weight, left1.72.67.1-2.7-1.30.9-1.41.6-1.8-1.9-1.71.71.70.01.5
Liver weight, right0.30.50.7-0.90.8-0.70.8-0.80.70.60.7-0.7-0.70.6-0.7
Locomotor activity1.32.12.7-0.11.6-1.61.6-1.61.51.31.6-1.6-1.61.0-1.6
Locomotor testing distance2.13.64.70.72.0-1.92.0-2.02.01.92.2-2.2-2.20.8-2.1
Locomotor testing rearing0.81.31.80.41.2-1.11.2-1.31.21.21.3-1.3-1.30.4-1.4
Locomotion in novel chamber0.80.91.20.71.1-1.01.1-1.11.00.91.0-1.0-1.00.9-0.9
Locomotion in novel chamber post-restriction0.30.30.4-0.40.5-0.40.5-0.60.60.60.6-0.6-0.60.1-0.6
Fecal boli incidents, locomotor time 11.61.72.50.71.2-1.11.3-1.41.51.51.6-1.6-1.60.4-1.2
Change in fecal boli incidents, locomotor task0.30.30.9-0.90.6-0.60.5-0.40.30.20.3-0.3-0.30.8-0.4
Time >=10cm from walls, locomotor time 10.20.21.20.3-0.20.5-0.1-0.10.20.40.1-0.1-0.1-1.1-0.1
Bouts of movement, locomotor time 10.00.00.00.20.0-0.10.0-0.10.10.10.2-0.2-0.2-0.1-0.0
Total resting periods, locomotor time 10.00.00.0-0.2-0.1-0.0-0.10.1-0.1-0.10.0-0.0-0.0-0.10.1
Rest time, locomotor task time 13.03.35.80.1-2.22.3-2.11.9-1.6-1.2-1.61.61.6-2.41.9
Distance moved, locomotor task time 11.71.92.9-1.01.6-1.71.5-1.41.20.91.3-1.3-1.31.5-1.5
Vertical activity count, locomotor time 10.30.30.50.00.7-0.70.6-0.60.40.30.4-0.4-0.40.7-0.7
Time >=10cm from walls, locomotor time 20.30.31.11.1-0.60.7-0.50.3-0.2-0.0-0.30.30.3-0.90.3
Bouts of movement, locomotor time 20.50.52.0-1.40.7-1.00.6-0.40.30.00.3-0.3-0.31.3-0.5
Total resting periods, locomotor time 20.50.52.7-1.70.7-0.90.6-0.30.20.00.3-0.3-0.31.1-0.4
Rest time, locomotor task time 20.60.71.70.00.4-0.10.6-0.81.01.31.0-1.0-1.0-0.8-0.7
Distance moved, locomotor task time 20.10.10.40.60.2-0.30.2-0.10.0-0.10.1-0.1-0.10.5-0.1
Vertical activity count, locomotor time 20.80.82.21.5-0.80.6-0.80.9-1.0-1.0-1.01.01.0-0.10.8
Light reinforcement 11.12.12.7-0.3-1.61.4-1.61.6-1.6-1.6-1.51.51.5-0.81.6
Light reinforcement 21.62.12.80.3-1.51.3-1.61.6-1.7-1.7-1.51.51.5-0.91.6
Bone: marrow area0.20.53.11.80.10.10.2-0.50.60.80.6-0.6-0.6-0.6-0.3
Bone: maximum diameter0.10.10.40.20.20.10.2-0.40.50.60.4-0.4-0.4-0.3-0.3
Bone: maximum force0.10.20.70.80.2-0.00.3-0.40.50.60.5-0.5-0.5-0.3-0.3
Bone: maximum moment0.10.21.11.00.00.20.1-0.30.40.60.4-0.4-0.4-0.5-0.2
Mean time between licks in bursts0.20.31.01.0-0.50.5-0.50.4-0.4-0.3-0.30.30.3-0.60.4
Mean num. licks in bursts2.53.03.80.2-2.01.9-1.91.9-1.8-1.7-1.91.91.9-1.21.8
Cd content in liver0.40.50.60.40.8-0.80.8-0.70.70.70.7-0.7-0.70.4-0.7
Co content in liver1.61.92.6-0.7-1.41.2-1.41.6-1.6-1.6-1.51.51.5-0.41.6
Cu content in liver0.91.04.80.8-1.21.6-1.00.6-0.4-0.0-0.60.60.6-2.20.7
Fe content in liver1.31.61.90.71.4-1.31.4-1.31.31.31.4-1.4-1.40.9-1.2
K content in liver2.22.13.10.4-1.71.7-1.71.6-1.5-1.3-1.41.41.4-1.31.8
Mg content in liver2.82.93.7-0.2-1.91.9-1.91.8-1.8-1.6-1.71.71.7-1.31.9
Mn content in liver4.14.76.2-0.8-2.31.9-2.32.5-2.5-2.5-2.32.32.3-0.72.5
Na content in liver0.20.20.5-0.7-0.2-0.0-0.30.4-0.5-0.6-0.40.40.40.40.3
Rb content in liver0.00.00.1-0.20.2-0.20.2-0.10.10.10.1-0.1-0.10.2-0.2
Se content in liver1.51.93.40.7-1.61.8-1.51.3-1.2-0.9-1.21.21.2-1.71.5
Sr content in liver0.40.42.41.0-0.50.7-0.40.2-0.10.1-0.20.20.2-1.6-0.2
Zn content in liver1.71.95.00.1-1.71.9-1.51.2-1.1-0.8-1.21.21.2-2.21.1
Bone: minimum diameter0.10.10.80.9-0.10.30.0-0.20.20.40.2-0.2-0.2-0.3-0.1
Time in familiar zone, hab. session 11.11.14.8-2.2-0.40.1-0.60.9-1.0-1.3-0.90.90.90.80.8
Time in novel zone, hab. session 10.60.61.61.30.5-0.20.6-0.70.81.00.8-0.8-0.8-0.5-0.8
Total zone transitions, hab. session 10.81.13.3-0.81.2-1.41.1-0.90.70.50.8-0.8-0.81.8-0.9
Total locomotion distance, hab. session 10.40.61.1-0.80.9-1.00.9-0.70.60.50.7-0.7-0.70.9-0.8
Locomotion velocity, hab. session 10.20.30.9-1.00.5-0.70.4-0.30.2-0.00.2-0.2-0.20.9-0.3
Time in familiar zone, hab. session 20.40.41.0-1.0-0.50.4-0.60.6-0.7-0.7-0.70.70.7-0.20.6
Time in novel zone, hab. session 20.70.72.71.70.4-0.20.6-0.80.91.10.8-0.8-0.8-0.3-0.7
Total zone transitions, hab. session 20.91.22.50.21.2-1.31.2-1.11.00.91.0-1.0-1.01.6-0.9
Total locomotion distance, hab. session 20.81.01.20.51.1-1.01.1-1.11.11.01.0-1.0-1.01.0-1.0
Locomotion velocity, hab. session 20.60.70.90.50.9-0.90.9-0.90.90.80.9-0.9-0.90.9-0.8
Novel to familiar place preference ratio0.60.63.1-1.60.6-1.00.5-0.1-0.0-0.40.2-0.2-0.21.8-0.2
Novelty place preference0.70.72.8-1.50.8-1.20.7-0.40.2-0.10.4-0.4-0.41.7-0.4
Time in novel zone, NPP test1.21.24.0-1.61.2-1.61.1-0.70.50.20.8-0.8-0.82.0-0.7
Total zone transitions, NPP test0.81.13.6-0.91.3-1.51.1-0.90.70.40.8-0.8-0.81.9-0.9
Total locomotion distance, NPP test0.91.22.5-0.21.3-1.31.2-1.11.00.81.0-1.0-1.01.6-1.0
Locomotion velocity, NPP test0.60.81.8-0.21.0-1.11.0-0.90.80.70.8-0.8-0.81.3-0.8
Intraocular pressure0.50.71.00.80.9-0.70.9-0.91.01.00.9-0.9-0.90.2-1.0
Delta distance traveled before/after self-admin0.10.10.2-0.50.3-0.40.3-0.30.30.30.3-0.3-0.30.3-0.3
Delta ambulatory time before/after self-admin0.20.20.5-0.70.5-0.70.5-0.30.30.10.4-0.4-0.40.7-0.3
Parametrial fat weight3.67.08.4-0.82.9-2.82.9-2.92.82.62.9-2.9-2.91.5-2.9
Pavlov. Cond. lever latency0.60.70.90.50.8-0.80.9-0.90.90.91.0-1.0-1.00.2-0.9
Pavlov. Cond. magazine entry latency0.10.10.70.8-0.20.4-0.2-0.00.10.2-0.00.00.0-0.70.1
Pavlov. Cond. change in total contacts0.40.42.31.5-0.10.50.1-0.40.50.80.3-0.3-0.3-1.1-0.3
Pavlov. Cond. index score0.70.91.20.1-1.11.1-1.11.0-1.0-0.9-1.11.11.1-0.71.1
Pavlov. Cond. latency score1.21.52.00.2-1.41.4-1.41.3-1.2-1.1-1.31.31.3-1.01.3
Pavlov. Cond. lever contacts1.72.02.4-0.2-1.61.5-1.61.5-1.5-1.4-1.61.61.6-0.91.5
Pavlov. Cond. magazine entry number0.10.20.3-0.4-0.40.3-0.40.5-0.5-0.5-0.40.40.4-0.00.5
Pavlov. Cond. intertrial magazine entries0.20.31.4-1.20.5-0.60.5-0.40.30.20.3-0.3-0.30.3-0.5
Pavlov. Cond. lever-magazine prob. diff.0.70.91.30.3-1.11.1-1.10.9-0.9-0.8-1.01.01.0-0.81.0
Pavlov. Cond. response bias0.00.10.1-0.1-0.20.2-0.20.2-0.2-0.2-0.30.30.3-0.20.2
Pavlov. Cond. lever latency0.20.30.8-0.50.6-0.70.5-0.30.30.10.4-0.4-0.40.9-0.4
Pavlov. Cond. magazine entry latency0.81.02.41.5-1.11.3-1.00.8-0.6-0.3-0.70.70.7-1.40.9
Pavlov. Cond. change in total contacts0.10.10.2-0.00.3-0.30.3-0.30.40.40.4-0.4-0.40.1-0.3
Pavlov. Cond. index score0.10.10.70.8-0.30.4-0.20.1-0.00.1-0.00.00.0-0.50.2
Pavlov. Cond. latency score0.20.20.80.9-0.50.7-0.40.3-0.2-0.0-0.20.20.2-0.70.4
Pavlov. Cond. lever contacts0.10.10.20.3-0.40.4-0.40.3-0.3-0.2-0.30.30.3-0.40.3
Pavlov. Cond. magazine entry number0.20.21.2-1.10.5-0.60.4-0.20.1-0.10.1-0.1-0.10.8-0.3
Pavlov. Cond. intertrial magazine entries0.40.62.5-1.60.0-0.4-0.10.5-0.7-1.0-0.50.50.51.30.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.7-0.30.3-0.20.1-0.00.1-0.00.00.0-0.40.2
Pavlov. Cond. response bias0.10.10.50.7-0.10.3-0.1-0.10.10.30.1-0.1-0.1-0.60.0
Time in closed arm before self-admin0.10.10.40.60.2-0.10.2-0.30.30.30.2-0.2-0.20.1-0.2
Time in closed arm after self-admin1.41.41.9-0.41.4-1.41.3-1.31.21.11.3-1.3-1.30.8-1.3
Time in open arm before self-admin0.30.40.70.5-0.70.6-0.70.7-0.6-0.6-0.60.60.6-0.30.8
Time in open arm after self-admin0.80.92.4-1.5-0.60.3-0.70.9-1.0-1.2-0.90.90.90.71.0
Bone: periosteal estimation0.20.31.81.30.10.20.2-0.40.50.70.5-0.5-0.5-0.6-0.2
Bone: periosteal perimeter0.10.10.30.30.10.10.2-0.30.40.50.3-0.3-0.3-0.3-0.2
Bone: post-yield work0.00.00.1-0.2-0.10.0-0.20.2-0.2-0.3-0.20.20.20.20.2
Progressive ratio test 1 active lever presses0.91.02.21.50.9-0.81.0-1.01.00.91.0-1.0-1.00.9-0.5
Progressive ratio test 1 breakpoint1.41.51.71.31.3-1.21.3-1.31.21.21.3-1.3-1.31.3-0.7
Progressive ratio test 1 inactive lever presses0.50.60.90.30.8-0.60.8-0.90.90.90.8-0.8-0.80.0-0.9
Progressive ratio test 2 active lever presses0.10.10.30.6-0.20.1-0.20.2-0.3-0.3-0.20.20.20.10.4
Progressive ratio test 2 breakpoint0.20.20.30.3-0.40.3-0.40.4-0.5-0.6-0.50.50.50.10.6
Progressive ratio test 2 inactive lever presses1.41.613.23.6-0.81.0-0.70.6-0.4-0.2-0.60.60.6-1.20.8
Incentive Sensitization - Responses0.40.41.41.2-0.50.6-0.50.4-0.3-0.2-0.40.40.4-1.10.2
Incentive Sensitization - Breakpoint0.40.41.00.8-0.60.7-0.60.5-0.5-0.4-0.60.60.6-1.00.3
Sum of active levers in priming session hrs 5-61.21.16.52.50.30.10.5-0.71.01.30.8-0.8-0.8-1.0-0.9
Progressive ratio2.93.44.7-0.6-2.01.8-2.02.2-2.0-2.0-1.91.91.9-0.92.1
Food seeking constrained by brief footshock0.40.42.3-1.50.0-0.4-0.10.4-0.5-0.7-0.30.30.31.20.4
Seeking ratio, punishment vs. effort2.02.43.5-0.41.8-1.91.8-1.71.51.31.5-1.5-1.51.6-1.6
Retroperitoneal fat weight1.44.55.51.72.2-2.02.2-2.32.32.32.3-2.3-2.31.3-2.0
Reaction time number correct0.10.20.3-0.20.5-0.40.5-0.50.50.50.5-0.5-0.5-0.1-0.5
Reaction time mean minus median1.11.54.32.1-1.21.1-1.21.3-1.2-1.1-1.01.01.0-0.61.2
Reaction time mean minus median AUC0.81.04.02.0-1.01.0-1.00.9-0.8-0.7-0.70.70.7-0.70.9
Reaction time num false alarms0.50.71.21.00.7-0.50.8-1.01.01.10.9-0.9-0.9-0.1-0.9
Reaction time num false alarms AUC0.20.30.50.60.4-0.20.4-0.60.60.70.5-0.5-0.5-0.1-0.5
Reaction time trials correct on left0.10.20.3-0.20.5-0.40.5-0.50.50.50.5-0.5-0.5-0.1-0.5
Reaction time trials on left0.10.10.2-0.30.4-0.30.4-0.40.40.40.4-0.4-0.4-0.1-0.4
Reaction time mean0.10.10.80.9-0.30.2-0.30.4-0.3-0.2-0.10.10.1-0.20.2
Reaction time mean AUC0.00.10.40.6-0.20.1-0.20.3-0.3-0.3-0.10.10.1-0.00.2
Median of all reaction times0.10.10.40.60.1-0.10.1-0.10.20.20.3-0.3-0.3-0.2-0.2
Reaction time omissions2.63.66.2-2.0-1.61.0-1.82.1-2.3-2.5-2.02.02.00.21.9
Reaction time false alarm rate0.10.20.90.90.10.00.2-0.40.40.50.4-0.4-0.4-0.3-0.3
Reaction time premature initiation rate1.62.12.6-0.91.6-1.61.6-1.51.51.41.6-1.6-1.61.1-1.5
Reaction time premature initiations1.62.22.7-1.11.6-1.61.6-1.51.51.41.6-1.6-1.61.0-1.5
Std. dev. reaction times0.60.81.40.4-0.90.7-1.01.1-1.1-1.2-0.90.90.90.11.0
Reaction time trials completed0.10.10.2-0.30.4-0.30.4-0.40.40.40.4-0.4-0.4-0.1-0.4
Reaction time trials AUC0.30.50.6-0.40.8-0.70.8-0.80.80.70.7-0.7-0.70.2-0.7
Run reversals in cocaine runway, females4.74.520.0-4.5-1.61.2-1.71.9-2.1-2.3-1.91.91.9-0.41.7
Run reversals in cocaine runway, males1.11.01.60.80.9-0.71.0-1.11.21.31.1-1.1-1.10.1-1.1
Latency to leave start box in cocaine runway1.21.313.8-3.7-0.0-0.2-0.10.3-0.5-0.6-0.30.30.30.50.2
Latency to leave start box in cocaine runway, F0.30.33.2-1.8-0.20.1-0.20.2-0.2-0.2-0.10.10.1-0.10.1
Latency to leave start box in cocaine runway, M2.32.214.5-3.81.1-1.70.9-0.40.0-0.50.4-0.4-0.42.5-0.4
Std. dev. time between licks in bursts1.31.64.72.2-1.41.7-1.20.9-0.7-0.4-0.90.90.9-1.80.9
Total sessions with >9 infusions1.01.112.73.6-0.10.4-0.0-0.10.30.50.2-0.2-0.2-0.30.2
Short access day 1 total inactive lever presses0.20.21.41.2-0.20.3-0.20.10.00.1-0.10.10.1-0.80.0
Short access day 10 total inactive lever presses0.20.21.10.9-0.00.20.1-0.20.30.50.2-0.2-0.2-1.0-0.6
Short access day 1 total infusions0.80.88.02.8-0.30.5-0.2-0.00.20.40.0-0.0-0.0-1.0-0.1
Short access day 10 total infusions1.82.021.54.6-0.60.8-0.50.3-0.10.1-0.30.30.3-0.30.9
Short access total infusions2.12.425.55.00.20.20.3-0.60.81.00.5-0.5-0.5-0.4-0.2
Short access day 1 locomotion3.63.819.74.4-1.82.1-1.71.4-1.1-0.6-1.41.41.4-2.11.4
Short access day 10 total locomotion0.80.910.53.2-0.30.5-0.2-0.00.20.4-0.10.10.1-0.50.1
Short access total locomotion3.94.132.15.7-1.51.8-1.31.0-0.7-0.3-1.11.11.1-1.81.2
One hour access (0.3 mA shock)1.41.69.23.00.8-0.60.9-1.11.11.21.0-1.0-1.00.3-0.7
Compulsive drug intake1.11.16.72.60.6-0.40.7-0.91.01.10.8-0.8-0.8-0.0-0.8
One hour access (shock baseline)0.00.10.40.60.2-0.20.1-0.20.10.10.2-0.2-0.20.30.1
Social response proportion0.20.20.4-0.2-0.50.5-0.50.6-0.5-0.5-0.50.50.5-0.40.4
Social responses1.01.31.80.2-1.31.2-1.31.3-1.2-1.1-1.11.11.1-1.21.1
Social time0.81.08.12.90.4-0.20.5-0.60.70.80.7-0.7-0.7-0.6-0.7
Soleus weight0.20.53.50.8-0.61.1-0.4-0.10.20.6-0.10.10.1-1.9-0.1
Bone: stiffness0.10.20.2-0.10.4-0.40.4-0.40.40.40.5-0.5-0.50.0-0.4
Tibialis anterior weight0.20.81.61.3-1.01.2-0.90.7-0.6-0.4-0.70.70.7-0.90.8
Time to tail flick, vehicle, before self-admin1.01.01.3-1.0-1.00.9-1.11.1-1.1-1.2-1.11.11.1-0.30.9
Time to tail flick, vehicle, after self-admin1.31.41.9-1.11.3-1.31.2-1.11.10.91.1-1.1-1.11.2-1.4
Time to tail flick, test, before self-admin2.22.12.9-0.21.6-1.41.6-1.61.71.71.6-1.6-1.60.9-1.4
Time to tail flick, test, after self-admin0.91.02.3-1.5-0.80.7-0.91.0-1.0-1.1-1.11.11.1-0.00.7
Delta time to tail flick, vehicle, before/after SA1.01.01.71.30.8-0.60.9-1.01.11.20.9-0.9-0.90.1-1.2
Delta time to tail flick, test, before/after SA2.01.85.5-2.3-1.00.7-1.11.3-1.5-1.6-1.41.41.40.30.9
Tibia length0.61.610.51.5-1.21.9-0.90.2-0.00.6-0.30.30.3-3.20.5
Ambulatory time before self-admin0.10.10.5-0.20.4-0.40.3-0.20.20.10.1-0.1-0.10.7-0.1
Ambulatory time after self-admin0.10.10.2-0.30.4-0.40.3-0.20.20.10.2-0.2-0.20.2-0.3
Bone: tissue strength0.40.40.60.10.7-0.70.7-0.60.60.50.6-0.6-0.60.8-0.6
Total heroin consumption0.91.11.80.11.0-1.01.1-1.11.11.11.3-1.3-1.30.1-0.9
Bone: trabecular number0.71.11.50.71.0-0.81.0-1.21.21.21.2-1.2-1.20.0-1.0
Bone: trabecular spacing0.10.10.2-0.2-0.40.3-0.40.4-0.4-0.4-0.40.40.4-0.20.3
Bone: trabecular thickness0.10.20.50.70.2-0.10.3-0.40.50.60.4-0.4-0.4-0.2-0.3
Bone: trabecular tissue density2.23.14.10.1-2.02.0-2.01.8-1.8-1.6-1.91.91.9-1.81.6
Water consumed over 24 hours1.92.33.2-0.41.8-1.81.7-1.61.51.31.6-1.6-1.61.6-1.5
Number of responses in last shaping day1.31.34.9-2.2-1.10.9-1.11.1-1.1-1.1-1.01.01.0-1.00.7