Hub : Genes

Speg

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative TSS XM_017596526.2 0.02 0.03 3.3e-03 0.02 0.01 0.02 0.01 5.7e-03 1.6e-02 2.9e-03 1.0e-02
2 Brain alternative TSS XM_006245252.4 0.04 0.04 1.9e-03 0.03 0.03 0.03 0.03 9.1e-04 9.9e-04 8.0e-04 8.8e-04
3 Brain alternative TSS XM_006245252.4 0.04 0.04 2.2e-03 0.03 0.03 0.03 0.03 1.1e-03 1.2e-03 9.8e-04 1.1e-03
4 IL intron excision ratio chr9_76875732_76878408 0.15 0.14 5.8e-03 0.06 0.04 0.01 0.05 1.4e-02 3.9e-02 1.4e-01 2.7e-02
5 BLA gene expression Speg 0.07 0.06 2.4e-03 0.03 0.04 0.04 0.04 7.1e-03 2.3e-03 4.3e-03 2.3e-03
6 PL isoform ratio XM_017596528.2 0.02 0.02 3.7e-03 0.02 0.02 0.02 0.01 3.1e-03 2.3e-03 5.2e-03 1.7e-02
7 PL alternative TSS XM_006245252.4 0.12 0.12 1.4e-12 0.11 0.12 0.12 0.12 3.7e-12 4.5e-13 6.1e-13 5.0e-13
8 PL alternative TSS XM_017596528.2 0.02 0.02 2.5e-03 0.01 0.02 0 0.01 1.2e-02 1.2e-03 1.1e-01 1.2e-02
9 NAcc alternative TSS XM_017596526.2 0.03 0.03 6.2e-05 0.03 0.03 0.03 0.03 1.2e-04 7.5e-05 2.6e-04 3.6e-04
10 Eye intron excision ratio chr9_76875555_76878408 0.36 0.26 8.2e-03 0.03 -0 -0.01 0.01 9.9e-02 3.3e-01 5.3e-01 1.9e-01
11 NAcc gene expression Speg 0.03 0.03 1.9e-04 0.01 0.01 0 0.01 5.8e-03 8.6e-03 1.0e-01 1.2e-02
12 PL gene expression Speg 0.09 0.05 5.4e-11 0.1 0.09 0.09 0.1 9.2e-11 5.3e-10 7.1e-10 1.0e-10
13 PL alternative TSS XM_006245252.4 0.12 0.14 9.9e-11 0.1 0.1 0.1 0.1 4.7e-11 6.4e-11 3.4e-11 2.6e-11
14 NAcc intron excision ratio chr9_76873724_76874610 0.04 0.04 3.7e-04 0.02 0.03 0.03 0.02 2.1e-03 6.2e-04 5.5e-04 9.7e-04
15 PL intron excision ratio chr9_76872721_76873682 0.03 0.03 1.1e-03 0.02 0.02 0.03 0.02 3.5e-03 1.1e-03 6.8e-04 1.0e-03
16 NAcc alternative TSS XM_006245252.4 0.07 0.06 1.9e-09 0.08 0.08 0.07 0.07 5.1e-10 1.6e-09 6.7e-09 9.4e-09
17 NAcc alternative TSS XM_017596526.2 0.04 0.03 4.0e-05 0.04 0.04 0.03 0.03 4.0e-05 6.0e-05 7.8e-05 1.8e-04
18 NAcc alternative TSS XM_006245252.4 0.07 0.06 9.1e-09 0.08 0.07 0.06 0.06 2.8e-09 8.1e-09 5.9e-08 4.6e-08
19 NAcc intron excision ratio chr9_76872721_76873682 0.04 0.03 1.1e-05 0.04 0.04 0.03 0.03 5.0e-05 6.1e-05 1.3e-04 1.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.00.00.20.4-0.3-0.2-0.4-0.10.1-0.10.20.2-0.20.20.2-0.2-0.20.20.2-0.20.20.2
Area under the delay curve2.62.73.7-1.7-1.7-1.91.31.6-1.61.6-1.6-1.61.7-1.7-1.71.71.7-1.6-1.71.7-1.7-1.7
BMI with tail0.00.10.30.6-0.3-0.1-0.5-0.20.3-0.20.30.3-0.20.20.2-0.2-0.10.10.1-0.10.10.1
BMI without tail0.10.31.0-0.40.81.0-0.3-0.30.3-0.30.30.3-0.50.50.5-0.5-0.50.50.5-0.50.50.5
Body weight0.73.14.00.51.81.6-1.9-1.81.8-1.81.81.8-1.81.81.8-1.8-1.82.01.8-1.81.81.8
Weight adjusted by age0.70.85.8-2.40.70.31.20.8-0.80.8-0.8-0.80.6-0.6-0.60.60.7-0.4-0.70.7-0.7-0.7
Bone surface0.20.32.30.8-1.5-1.2-0.10.3-0.30.3-0.2-0.20.4-0.4-0.40.40.4-0.4-0.40.4-0.4-0.4
Bone volume0.00.10.40.6-0.6-0.4-0.4-0.10.1-0.10.10.1-0.10.10.1-0.1-0.10.10.1-0.10.10.1
Breakpoint value in progressive ratio session0.30.41.1-0.3-0.2-0.31.00.6-0.60.6-0.7-0.60.6-0.6-0.60.60.5-0.6-0.60.6-0.6-0.6
Number of licking bursts0.10.20.30.00.40.6-0.4-0.30.3-0.30.30.3-0.40.40.4-0.4-0.40.50.4-0.40.40.4
Context. condit. distance diff. score0.60.72.81.70.60.9-0.8-0.80.8-0.80.80.8-0.80.80.8-0.8-0.80.50.8-0.80.80.8
Locomotion velocity, session 10.10.10.60.80.30.4-0.3-0.30.3-0.30.30.4-0.30.30.3-0.3-0.30.20.3-0.30.30.3
Locomotion distance, session 10.00.10.30.50.50.50.10.1-0.10.1-0.1-0.10.1-0.1-0.10.10.1-0.4-0.10.1-0.1-0.1
Locomotion velocity, session 21.01.21.2-1.1-0.8-0.91.11.1-1.11.1-1.1-1.11.1-1.1-1.11.11.1-1.1-1.11.1-1.1-1.1
Locomotion distance, session 23.34.66.1-1.0-1.8-1.72.12.2-2.22.2-2.2-2.22.2-2.2-2.22.22.2-2.5-2.22.2-2.2-2.2
Locomotion velocity, session 31.61.92.3-1.4-0.7-0.91.51.4-1.41.4-1.4-1.41.4-1.4-1.41.41.4-1.5-1.41.4-1.4-1.4
Locomotion distance, session 30.00.00.1-0.00.40.40.10.1-0.10.1-0.1-0.10.0-0.0-0.00.00.0-0.2-0.00.0-0.0-0.0
Stereotopy head waving bouts, day 30.00.00.10.20.00.1-0.3-0.20.2-0.20.20.2-0.20.20.2-0.2-0.20.30.2-0.20.20.2
Stereotopy head waving duration, day 30.10.10.20.4-0.2-0.1-0.4-0.30.3-0.30.30.3-0.30.30.3-0.3-0.30.30.3-0.30.30.3
Locomotion velocity, session 70.30.30.7-0.8-0.5-0.60.60.5-0.50.5-0.5-0.50.5-0.5-0.50.50.5-0.3-0.50.5-0.5-0.5
Locomotion distance, session 70.10.20.3-0.5-0.2-0.20.60.4-0.40.4-0.5-0.50.4-0.4-0.40.40.4-0.4-0.40.4-0.4-0.4
Stereotopy head waving bouts, day 70.40.41.4-0.4-1.2-1.10.40.5-0.50.5-0.5-0.50.6-0.6-0.60.60.6-0.5-0.60.6-0.6-0.6
Stereotopy head waving duration, day 70.50.61.6-0.5-1.3-1.20.60.7-0.70.7-0.7-0.70.8-0.8-0.80.80.8-0.7-0.80.8-0.8-0.8
Locomotion velocity, session 81.61.92.4-0.5-1.2-1.11.51.4-1.41.4-1.4-1.41.4-1.4-1.41.41.4-1.5-1.41.4-1.4-1.4
Locomotion distance, session 80.30.51.00.8-0.7-0.40.60.7-0.70.7-0.7-0.70.7-0.7-0.70.70.7-1.0-0.70.7-0.7-0.7
Degree of sensitization distance0.00.00.1-0.2-0.4-0.40.10.1-0.10.1-0.1-0.10.1-0.1-0.10.10.10.1-0.10.1-0.1-0.1
Degree of sensitization stereotypy0.91.01.7-0.8-1.3-1.30.81.0-1.01.0-0.9-0.91.0-1.0-1.01.01.0-0.9-1.01.0-1.0-1.0
Conditioned locomotion0.30.30.40.40.50.6-0.7-0.50.5-0.50.50.5-0.60.60.6-0.6-0.60.60.6-0.60.60.6
Cocaine response after cond. corrected7.68.69.02.52.82.8-2.8-3.03.0-3.03.03.0-3.03.03.0-3.0-3.02.93.0-3.03.03.0
Cocaine response after cond. not corrected7.58.310.42.03.23.1-2.6-2.92.9-2.92.92.9-2.92.92.9-2.9-2.92.92.9-2.92.92.9
Cocaine response before conditioning0.20.21.1-1.00.60.30.60.5-0.50.5-0.5-0.50.4-0.4-0.40.40.4-0.4-0.40.4-0.4-0.4
Saline control response1.41.92.5-1.5-0.5-0.71.61.4-1.41.4-1.4-1.41.4-1.4-1.41.41.4-1.5-1.41.4-1.4-1.4
Bone: connectivity density0.10.20.70.8-0.1-0.0-0.6-0.50.5-0.50.50.5-0.40.40.4-0.4-0.40.40.4-0.40.40.4
Bone: cortical apparent density0.20.20.4-0.1-0.6-0.60.40.5-0.50.5-0.5-0.50.5-0.5-0.50.50.5-0.5-0.50.5-0.5-0.5
Bone: cortical area0.00.00.1-0.1-0.4-0.30.10.2-0.20.2-0.2-0.20.2-0.2-0.20.20.2-0.1-0.20.2-0.2-0.2
Bone: cortical porosity0.10.10.2-0.3-0.2-0.20.40.4-0.40.4-0.4-0.40.3-0.3-0.30.40.4-0.4-0.30.3-0.3-0.3
Bone: cortical porosity0.10.10.5-0.70.30.20.40.2-0.20.2-0.3-0.30.2-0.2-0.20.20.2-0.2-0.20.2-0.2-0.2
Bone: cortical thickness0.00.00.0-0.10.10.1-0.2-0.10.1-0.10.10.1-0.20.20.2-0.2-0.20.20.2-0.20.20.2
Bone: cortical thickness0.10.10.70.8-0.8-0.5-0.3-0.10.1-0.00.10.10.0-0.0-0.00.00.0-0.1-0.00.0-0.0-0.0
Bone: cortical tissue density0.20.30.4-0.1-0.6-0.60.40.5-0.50.5-0.5-0.50.5-0.5-0.50.50.5-0.5-0.50.5-0.5-0.5
Condit. Reinf. active minus inactive responses0.00.00.5-0.7-0.1-0.2-0.1-0.00.0-0.00.00.0-0.00.00.00.0-0.00.20.0-0.00.00.0
Condit. Reinf. active-inactive response ratio0.40.50.9-0.70.90.7-0.5-0.60.6-0.60.60.6-0.70.70.7-0.6-0.70.90.7-0.70.70.7
Condit. Reinf. active responses0.00.00.1-0.2-0.4-0.4-0.00.1-0.10.1-0.1-0.10.1-0.1-0.10.10.1-0.1-0.10.1-0.1-0.1
Condit. Reinf. inactive responses0.20.31.20.7-1.1-0.80.10.4-0.40.4-0.4-0.40.5-0.5-0.50.40.5-0.6-0.50.5-0.5-0.5
Incentive salience index mean0.00.00.1-0.2-0.3-0.3-0.00.1-0.10.1-0.1-0.10.1-0.1-0.10.10.1-0.1-0.10.1-0.1-0.1
Condit. Reinf. lever presses0.20.31.01.00.10.2-0.7-0.50.5-0.50.50.5-0.50.50.5-0.5-0.50.40.5-0.50.50.5
Condit. Reinf. active minus inactive responses0.10.10.6-0.50.80.6-0.0-0.20.2-0.20.20.2-0.30.30.3-0.3-0.30.40.3-0.30.30.3
Condit. Reinf. active-inactive response ratio0.40.40.9-0.10.90.7-0.4-0.60.6-0.60.60.6-0.70.70.7-0.7-0.70.80.7-0.70.70.7
Condit. Reinf. active responses0.10.10.6-0.80.30.20.50.4-0.40.4-0.4-0.40.3-0.3-0.30.30.3-0.3-0.30.3-0.3-0.3
Condit. Reinf. inactive responses1.82.22.9-0.9-1.2-1.01.51.6-1.61.6-1.6-1.61.6-1.6-1.61.61.6-1.7-1.61.6-1.6-1.6
Condit. Reinf. lever presses0.50.73.5-1.90.2-0.21.20.8-0.90.8-0.9-0.90.7-0.7-0.70.70.6-0.5-0.70.7-0.7-0.7
Condit. Reinf. lever reinforcers received0.20.20.8-0.90.1-0.00.70.5-0.50.5-0.5-0.50.4-0.4-0.40.40.4-0.4-0.40.4-0.4-0.4
Conditioned reinforcement - actives0.30.30.60.0-0.8-0.60.50.7-0.70.7-0.7-0.60.6-0.6-0.60.50.6-0.4-0.60.6-0.6-0.6
Conditioned reinforcement - inactives1.41.67.6-0.72.82.6-0.3-0.70.7-0.80.70.7-1.21.21.2-1.1-1.11.41.1-1.11.11.1
Conditioned locomotion1.82.27.90.1-2.8-2.60.41.3-1.31.3-1.2-1.21.4-1.4-1.41.41.4-1.3-1.41.4-1.4-1.4
Patch foraging indifference point 0 sec7.412.024.5-4.9-1.8-2.13.73.8-3.83.7-3.8-3.83.3-3.3-3.33.43.4-3.2-3.33.3-3.3-3.3
Patch foraging indifference point AUC0.50.66.22.5-1.7-1.4-0.5-0.10.1-0.10.20.20.3-0.3-0.30.20.1-0.4-0.10.1-0.1-0.1
Delay disc. indifference point, 0s delay0.80.91.4-0.7-0.5-0.61.21.0-1.01.0-1.0-1.01.0-1.0-1.01.01.0-1.1-1.01.0-1.0-1.0
Delay disc. indifference point, 16s delay0.70.72.0-1.4-0.4-0.80.70.8-0.80.8-0.8-0.80.8-0.8-0.80.90.8-0.7-0.80.8-0.8-0.8
Delay disc. indifference point, 2s delay4.34.75.5-2.1-2.2-2.31.92.2-2.22.2-2.1-2.12.2-2.2-2.22.22.2-2.1-2.22.2-2.2-2.2
Delay disc. indifference point, 24s delay0.10.11.2-1.10.1-0.4-0.3-0.00.1-0.00.10.00.1-0.1-0.10.10.10.2-0.10.1-0.1-0.1
Delay disc. indifference point, 4s delay1.81.92.5-0.8-1.6-1.51.21.4-1.41.4-1.4-1.41.4-1.4-1.41.41.4-1.5-1.41.4-1.4-1.4
Delay disc. indifference point, 8s delay3.43.56.6-1.6-2.5-2.61.21.8-1.81.8-1.7-1.71.9-1.9-1.91.91.9-1.8-1.91.9-1.9-1.9
Indifference point function ln k0.40.63.9-2.00.10.00.90.7-0.70.7-0.8-0.70.5-0.5-0.50.60.6-0.4-0.60.6-0.6-0.6
Indifference point function log k0.40.63.9-2.00.10.00.90.7-0.70.7-0.8-0.70.5-0.5-0.50.60.6-0.4-0.60.6-0.6-0.6
Patch foraging total patch changes 0 sec6.811.024.9-5.0-1.9-2.23.53.6-3.63.6-3.6-3.63.1-3.1-3.13.23.2-2.9-3.23.2-3.2-3.2
Patch foraging total patch changes 12 sec4.35.66.6-2.6-1.9-2.12.42.5-2.52.4-2.5-2.52.4-2.4-2.42.52.3-2.3-2.32.3-2.3-2.3
Patch foraging total patch changes 18 sec3.34.25.2-1.9-2.3-2.01.72.3-2.32.2-2.2-2.22.0-2.0-2.02.02.0-1.9-2.02.0-2.0-2.0
Patch foraging total patch changes 24 sec3.03.711.1-3.3-1.2-1.21.82.1-2.12.1-2.1-2.11.7-1.7-1.71.71.8-1.5-1.81.8-1.8-1.8
Patch foraging total patch changes 6 sec2.74.14.7-1.9-2.0-1.82.02.2-2.22.2-2.2-2.12.0-2.0-2.02.01.9-2.1-1.91.9-1.9-1.9
Patch foraging time to switch 0 sec1.01.57.1-1.82.72.4-0.3-0.60.6-0.70.60.6-1.11.11.1-1.0-1.01.21.0-1.01.01.0
Patch foraging water rate 0 sec0.20.31.80.8-1.3-1.30.10.2-0.20.2-0.2-0.20.4-0.4-0.40.40.4-0.3-0.40.4-0.4-0.4
Patch foraging water rate 12 sec0.81.32.8-0.1-1.7-1.61.11.0-1.01.0-1.0-1.01.1-1.1-1.11.11.1-1.0-1.11.1-1.1-1.1
Patch foraging water rate 18 sec0.00.00.20.2-0.3-0.40.10.0-0.00.0-0.0-0.00.1-0.1-0.10.10.1-0.0-0.10.1-0.1-0.1
Patch foraging water rate 24 sec0.91.34.2-1.0-2.0-1.80.61.1-1.11.1-1.0-1.01.0-1.0-1.01.01.0-0.8-1.01.0-1.0-1.0
Patch foraging water rate 6 sec0.60.92.1-1.4-0.3-0.61.20.9-0.90.9-1.0-1.00.9-0.9-0.90.90.9-0.7-0.90.9-0.9-0.9
Seeking ratio, delayed vs. immediate footshock0.00.10.40.40.60.40.40.0-0.00.0-0.1-0.10.0-0.0-0.00.00.0-0.1-0.00.0-0.0-0.0
Distance traveled before self-admin0.10.11.3-1.20.20.1-0.0-0.10.1-0.10.10.1-0.10.10.1-0.1-0.20.30.1-0.10.10.1
Distance traveled after self-admin1.82.02.2-1.4-1.3-1.31.21.5-1.51.5-1.5-1.51.4-1.4-1.41.41.4-1.3-1.41.4-1.4-1.4
Extensor digitorum longus weight0.10.52.40.4-1.6-1.30.20.5-0.50.5-0.5-0.50.7-0.7-0.70.70.7-0.7-0.70.7-0.7-0.7
Bone: elastic displacement3.13.54.4-1.3-2.1-2.11.71.9-1.91.9-1.9-1.91.9-1.9-1.91.91.9-1.9-1.91.9-1.9-1.9
Bone: elastic work0.70.90.9-0.7-1.0-1.00.91.0-1.01.0-1.0-0.90.9-0.9-0.90.90.9-0.9-0.90.9-0.9-0.9
Bone: endosteal estimation1.53.23.5-1.3-1.8-1.91.71.8-1.81.8-1.8-1.81.8-1.8-1.81.81.8-1.9-1.81.8-1.8-1.8
Bone: endosteal perimeter0.20.40.50.60.50.5-0.7-0.70.7-0.70.70.7-0.60.60.6-0.6-0.60.60.6-0.60.60.6
Epididymis fat weight1.53.55.01.32.02.2-1.7-1.61.6-1.61.61.6-2.02.02.0-2.0-2.02.02.0-2.02.02.0
Delta time in closed arm before/after self-admin0.80.83.3-1.21.20.91.80.9-0.90.9-0.9-0.90.6-0.6-0.60.70.8-0.7-0.60.6-0.6-0.6
Delta time in open arm before/after self-admin3.13.04.70.32.22.1-1.6-1.61.6-1.61.61.6-1.81.81.8-1.8-1.81.81.8-1.81.81.8
Diff in mean of infusions in LGA sessions0.80.82.4-0.2-1.6-1.30.40.9-0.90.9-0.8-0.80.9-0.9-0.90.90.9-0.9-0.90.9-0.9-0.9
Delay discount exponential model param2.22.33.11.61.51.7-1.3-1.51.5-1.51.41.5-1.51.51.5-1.5-1.51.41.5-1.51.51.5
Extinction: sum of active levers before priming0.30.31.30.1-1.1-1.00.20.5-0.50.5-0.5-0.50.5-0.5-0.50.50.4-0.4-0.50.5-0.5-0.5
Active lever presses in extinction session 60.70.71.70.8-1.3-1.10.70.7-0.70.7-0.7-0.70.8-0.8-0.80.70.7-0.9-0.80.8-0.8-0.8
Bone: final force1.01.71.8-0.9-1.3-1.31.21.3-1.31.3-1.3-1.31.3-1.3-1.31.31.3-1.3-1.31.3-1.3-1.3
Bone: final moment1.52.52.8-1.0-1.7-1.71.51.6-1.61.6-1.6-1.61.6-1.6-1.61.61.6-1.6-1.61.6-1.6-1.6
Food consumed during 24 hour testing period0.10.10.60.6-0.7-0.80.10.1-0.10.1-0.1-0.10.3-0.3-0.30.30.3-0.4-0.30.3-0.3-0.3
Glucose0.00.00.20.40.20.30.1-0.00.0-0.00.00.0-0.00.00.0-0.0-0.0-0.20.0-0.00.00.0
Heart weight0.60.84.51.0-2.1-2.0-0.10.4-0.40.4-0.4-0.40.6-0.6-0.60.60.8-0.5-0.80.8-0.8-0.8
Delay discount hyperbolic model param3.23.44.21.81.92.1-1.6-1.81.8-1.81.81.8-1.91.91.9-1.9-1.91.81.9-1.91.91.9
Intermittent access intake day 1-15 change1.41.414.1-3.80.3-0.10.91.1-1.11.1-1.1-1.10.8-0.8-0.80.80.7-0.3-0.70.7-0.7-0.7
Intermittent access intake escalation1.91.912.6-3.6-0.2-0.61.21.4-1.41.4-1.4-1.41.1-1.1-1.11.21.0-0.7-1.01.0-1.0-1.0
Intermittent access intake escalation 22.12.111.0-3.3-0.8-1.41.01.4-1.31.3-1.3-1.41.4-1.4-1.41.41.3-0.8-1.31.3-1.3-1.3
Intermitt. access day 1 inactive lever presses0.80.85.2-1.82.31.91.30.5-0.60.5-0.6-0.60.1-0.1-0.10.20.1-0.3-0.10.1-0.1-0.1
Intermitt. access day 15 inactive lever presses0.91.05.2-1.72.22.30.1-0.20.2-0.20.10.2-0.80.80.8-0.7-0.80.70.8-0.80.80.8
Intermitt. access escalation Index0.50.44.22.10.60.5-0.1-0.50.5-0.50.50.5-0.40.40.4-0.4-0.4-0.20.4-0.40.40.4
Intermittent access day 1 total infusions0.20.34.42.1-0.3-0.20.3-0.10.1-0.00.00.00.2-0.2-0.20.10.2-0.2-0.20.2-0.2-0.2
Intermittent access day 15 total infusions0.20.21.5-1.20.80.50.70.5-0.50.4-0.5-0.50.2-0.2-0.20.30.20.1-0.20.2-0.2-0.2
Intermittent access terminal intake (last 3 days)0.40.42.2-1.50.60.31.10.6-0.60.6-0.7-0.70.5-0.5-0.50.50.5-0.0-0.50.5-0.5-0.5
Intermittent access total infusions0.10.10.40.60.40.30.50.1-0.10.1-0.1-0.10.1-0.1-0.10.10.10.0-0.10.1-0.1-0.1
Intermittent access day 1 locomotion0.10.11.11.10.20.10.50.1-0.10.1-0.1-0.10.2-0.2-0.20.20.3-0.4-0.30.3-0.3-0.3
Intermittent access day 15 total locomotion1.21.213.1-3.60.30.20.81.1-1.11.0-1.1-1.10.6-0.6-0.60.70.7-0.2-0.70.7-0.7-0.7
Intermittent access total locomotion0.40.51.2-1.1-0.2-0.30.80.8-0.80.7-0.8-0.70.6-0.6-0.60.60.7-0.5-0.70.7-0.7-0.7
Intermittent access standard deviation2.22.329.2-5.42.01.41.31.1-1.11.0-1.2-1.10.4-0.4-0.40.60.40.2-0.40.4-0.4-0.4
Left kidney weight0.10.42.01.4-0.3-0.6-1.0-0.70.7-0.70.70.7-0.40.40.4-0.4-0.40.60.4-0.40.40.4
Right kidney weight0.41.12.71.60.30.0-1.3-1.21.2-1.21.21.2-0.90.90.9-0.9-0.91.10.9-0.90.90.9
Cocaine induced anxiety0.91.11.5-0.5-0.8-1.21.00.9-0.90.9-0.9-0.91.1-1.1-1.11.11.1-1.1-1.11.1-1.1-1.1
Post-drug Anxiety2.32.53.4-1.9-1.7-1.81.31.5-1.51.5-1.5-1.51.6-1.6-1.61.61.6-1.5-1.61.6-1.6-1.6
Baseline Anxiety0.30.32.21.0-1.5-0.5-0.9-0.20.2-0.20.20.3-0.30.30.3-0.4-0.30.30.3-0.30.30.3
Tail length1.64.710.4-0.53.23.1-1.5-1.81.8-1.81.71.8-2.22.22.2-2.2-2.22.42.3-2.32.32.3
Length with tail1.55.68.90.53.02.6-2.0-2.32.3-2.32.22.2-2.42.42.4-2.4-2.42.72.4-2.42.42.4
Length without tail0.51.21.70.70.90.5-1.3-1.31.3-1.21.31.2-1.11.11.1-1.1-1.01.31.0-1.01.01.0
Times rat made contact with spout0.00.00.1-0.40.10.10.20.2-0.20.2-0.2-0.20.1-0.1-0.10.10.1-0.1-0.10.1-0.1-0.1
Lifetime Intake0.10.11.01.0-0.1-0.00.60.2-0.30.3-0.3-0.30.3-0.3-0.30.30.3-0.1-0.30.3-0.3-0.3
Liver weight, left0.10.11.21.1-0.20.2-0.3-0.10.1-0.10.10.2-0.20.20.2-0.2-0.20.00.2-0.20.20.2
Liver weight, right3.45.616.30.94.04.0-1.5-2.12.0-2.12.02.0-2.32.32.3-2.2-2.31.92.3-2.32.32.3
Locomotor activity1.21.92.5-1.6-0.8-1.01.61.4-1.41.4-1.4-1.41.4-1.4-1.41.41.4-1.4-1.41.4-1.4-1.4
Locomotor testing distance3.25.35.9-2.2-1.8-2.12.42.3-2.32.3-2.3-2.32.3-2.3-2.32.32.3-2.3-2.42.4-2.4-2.4
Locomotor testing rearing5.78.89.7-2.4-2.5-2.73.13.0-3.03.0-3.0-3.03.0-3.0-3.03.03.1-3.0-3.13.1-3.1-3.1
Locomotion in novel chamber0.60.83.71.7-1.9-1.40.20.5-0.50.5-0.5-0.50.7-0.7-0.70.60.7-0.9-0.70.7-0.7-0.7
Locomotion in novel chamber post-restriction0.20.31.90.31.41.10.3-0.40.3-0.30.30.3-0.30.30.3-0.3-0.40.40.3-0.30.30.3
Fecal boli incidents, locomotor time 10.20.20.40.60.50.5-0.3-0.50.5-0.50.50.5-0.40.40.4-0.4-0.40.20.4-0.40.40.4
Change in fecal boli incidents, locomotor task0.10.10.3-0.6-0.5-0.50.00.2-0.20.2-0.2-0.20.2-0.2-0.20.30.2-0.1-0.20.2-0.2-0.2
Time >=10cm from walls, locomotor time 11.11.22.9-0.6-1.7-1.60.61.0-1.01.0-0.9-0.91.1-1.1-1.11.01.0-1.1-1.11.1-1.1-1.1
Bouts of movement, locomotor time 10.00.00.10.20.00.1-0.3-0.20.2-0.20.20.2-0.20.20.2-0.2-0.20.20.2-0.20.20.2
Total resting periods, locomotor time 10.00.10.3-0.6-0.2-0.30.10.2-0.20.2-0.2-0.20.2-0.2-0.20.20.2-0.1-0.20.2-0.2-0.2
Rest time, locomotor task time 10.00.10.1-0.2-0.2-0.20.20.2-0.20.2-0.2-0.20.2-0.2-0.20.20.2-0.2-0.20.2-0.2-0.2
Distance moved, locomotor task time 10.00.00.20.40.00.00.40.2-0.20.2-0.2-0.20.2-0.2-0.20.20.2-0.4-0.20.2-0.2-0.2
Vertical activity count, locomotor time 10.00.00.20.40.1-0.00.20.1-0.10.1-0.1-0.10.1-0.1-0.10.10.1-0.3-0.10.1-0.1-0.1
Time >=10cm from walls, locomotor time 20.60.61.8-1.3-1.3-1.40.10.6-0.60.6-0.6-0.60.7-0.7-0.70.70.7-0.4-0.70.7-0.7-0.7
Bouts of movement, locomotor time 20.10.10.30.2-0.5-0.30.20.3-0.30.3-0.3-0.30.3-0.3-0.30.30.3-0.4-0.30.3-0.3-0.3
Total resting periods, locomotor time 20.20.20.50.1-0.7-0.50.30.4-0.40.4-0.4-0.40.4-0.4-0.40.40.4-0.5-0.40.4-0.4-0.4
Rest time, locomotor task time 21.01.11.5-0.7-1.2-1.20.91.1-1.01.1-1.0-1.01.1-1.1-1.11.11.1-1.2-1.11.1-1.1-1.1
Distance moved, locomotor task time 20.00.00.10.3-0.00.1-0.0-0.10.0-0.10.00.1-0.10.10.1-0.1-0.10.00.1-0.10.10.1
Vertical activity count, locomotor time 20.90.94.42.10.50.8-0.8-0.90.9-0.90.90.9-0.90.90.9-0.9-0.90.50.9-0.90.90.9
Light reinforcement 12.95.311.0-3.3-1.0-1.32.62.3-2.32.3-2.4-2.42.3-2.3-2.32.32.3-2.2-2.32.3-2.3-2.3
Light reinforcement 21.52.03.9-2.0-0.3-0.61.61.4-1.41.4-1.4-1.51.4-1.4-1.41.51.4-1.5-1.41.4-1.4-1.4
Bone: marrow area1.53.23.5-1.4-1.8-1.81.71.8-1.81.8-1.8-1.81.9-1.9-1.91.81.9-1.9-1.91.9-1.9-1.9
Bone: maximum diameter0.30.60.70.60.80.8-0.7-0.80.8-0.80.80.8-0.80.80.8-0.8-0.80.80.8-0.80.80.8
Bone: maximum force1.72.93.0-1.4-1.7-1.71.61.7-1.71.7-1.7-1.71.7-1.7-1.71.71.7-1.7-1.71.7-1.7-1.7
Bone: maximum moment2.44.14.3-1.6-2.1-2.11.92.0-2.02.0-2.0-2.02.1-2.1-2.12.02.1-2.1-2.12.1-2.1-2.1
Mean time between licks in bursts2.02.86.4-2.5-0.6-0.81.91.8-1.81.8-1.8-1.81.6-1.6-1.61.61.6-1.5-1.61.6-1.6-1.6
Mean num. licks in bursts0.81.01.1-0.7-0.9-1.01.01.0-1.01.0-1.0-1.01.0-1.0-1.01.01.0-1.0-1.01.0-1.0-1.0
Cd content in liver1.31.41.9-1.3-0.6-0.81.41.2-1.21.2-1.2-1.21.2-1.2-1.21.21.2-1.2-1.21.2-1.2-1.2
Co content in liver2.83.34.4-1.8-1.0-1.22.11.9-1.91.9-1.9-1.91.9-1.9-1.91.91.9-2.0-1.91.9-1.9-1.9
Cu content in liver1.11.32.10.31.51.3-1.0-1.11.1-1.11.11.1-1.11.11.1-1.1-1.11.21.1-1.11.11.1
Fe content in liver0.00.00.1-0.1-0.0-0.0-0.2-0.10.1-0.10.10.1-0.10.10.1-0.1-0.10.30.1-0.10.10.1
K content in liver0.50.51.6-0.41.31.0-0.4-0.60.6-0.60.60.6-0.60.60.6-0.6-0.60.70.6-0.60.60.6
Mg content in liver0.00.00.2-0.40.40.30.0-0.00.0-0.00.00.0-0.10.10.1-0.0-0.10.10.1-0.10.10.1
Mn content in liver0.40.40.6-0.4-0.4-0.50.70.7-0.70.7-0.7-0.70.7-0.7-0.70.70.7-0.8-0.70.7-0.7-0.7
Na content in liver0.30.32.3-0.41.51.20.1-0.30.3-0.30.30.3-0.40.40.4-0.3-0.40.30.4-0.40.40.4
Rb content in liver0.50.60.70.60.60.7-0.9-0.80.8-0.80.80.8-0.80.80.8-0.8-0.80.80.8-0.80.80.8
Se content in liver1.01.21.60.81.31.2-0.9-1.11.1-1.11.11.1-1.11.11.1-1.1-1.11.11.1-1.11.11.1
Sr content in liver0.00.00.0-0.1-0.1-0.10.10.2-0.20.2-0.2-0.20.1-0.1-0.10.10.1-0.1-0.10.1-0.1-0.1
Zn content in liver0.10.20.3-0.20.50.4-0.4-0.40.4-0.40.40.4-0.40.40.4-0.4-0.40.50.4-0.40.40.4
Bone: minimum diameter0.71.31.9-0.8-1.4-1.31.01.1-1.11.1-1.1-1.11.2-1.2-1.21.11.2-1.1-1.21.2-1.2-1.2
Time in familiar zone, hab. session 14.03.84.61.72.12.1-1.7-1.91.9-1.91.91.9-2.02.02.0-2.0-2.01.92.0-2.02.02.0
Time in novel zone, hab. session 11.81.72.7-1.0-1.6-1.61.11.3-1.31.3-1.3-1.31.3-1.3-1.31.31.3-1.3-1.31.3-1.3-1.3
Total zone transitions, hab. session 10.20.30.6-0.2-0.1-0.10.60.6-0.60.6-0.6-0.60.6-0.6-0.60.60.6-0.7-0.60.6-0.6-0.6
Total locomotion distance, hab. session 10.10.10.30.5-0.10.00.30.3-0.30.3-0.3-0.30.3-0.3-0.30.30.3-0.6-0.30.3-0.3-0.3
Locomotion velocity, hab. session 10.20.20.60.4-0.2-0.10.50.5-0.50.5-0.5-0.50.5-0.5-0.50.50.5-0.7-0.50.5-0.5-0.5
Time in familiar zone, hab. session 22.32.42.71.31.61.6-1.4-1.51.5-1.51.51.5-1.61.61.6-1.6-1.61.51.6-1.61.61.6
Time in novel zone, hab. session 23.23.24.2-1.9-2.0-2.01.61.8-1.81.8-1.7-1.81.8-1.8-1.81.81.8-1.6-1.81.8-1.8-1.8
Total zone transitions, hab. session 20.00.10.60.00.80.70.1-0.10.1-0.10.10.0-0.10.10.1-0.1-0.1-0.10.1-0.10.10.1
Total locomotion distance, hab. session 20.00.00.20.50.40.50.10.0-0.00.0-0.0-0.0-0.00.00.00.0-0.0-0.20.0-0.00.00.0
Locomotion velocity, hab. session 20.20.20.80.80.80.9-0.3-0.40.4-0.40.40.4-0.40.40.4-0.4-0.40.10.4-0.40.40.4
Novel to familiar place preference ratio0.80.81.81.30.60.7-0.9-0.90.9-0.90.90.9-0.90.90.9-0.9-0.90.80.9-0.90.90.9
Novelty place preference0.30.30.60.70.40.5-0.5-0.50.5-0.50.50.5-0.50.50.5-0.5-0.50.40.5-0.50.50.5
Time in novel zone, NPP test0.10.10.30.50.10.2-0.3-0.30.3-0.30.30.3-0.30.30.3-0.3-0.30.30.3-0.30.30.3
Total zone transitions, NPP test0.00.10.40.60.60.60.1-0.0-0.00.0-0.0-0.0-0.00.00.0-0.0-0.0-0.30.0-0.00.00.0
Total locomotion distance, NPP test0.20.30.60.5-0.5-0.30.50.5-0.50.6-0.5-0.50.5-0.5-0.50.50.5-0.8-0.50.5-0.5-0.5
Locomotion velocity, NPP test0.20.30.70.4-0.3-0.20.50.5-0.50.6-0.5-0.50.5-0.5-0.50.50.5-0.8-0.50.5-0.5-0.5
Intraocular pressure1.42.06.70.9-2.6-2.20.71.1-1.11.1-1.1-1.11.4-1.4-1.41.31.3-1.6-1.31.3-1.3-1.3
Delta distance traveled before/after self-admin2.93.13.6-1.6-1.5-1.51.51.9-1.91.9-1.9-1.91.8-1.8-1.81.81.8-1.8-1.81.8-1.8-1.8
Delta ambulatory time before/after self-admin4.85.35.9-1.7-2.3-2.42.02.3-2.32.3-2.3-2.32.4-2.4-2.42.42.3-2.4-2.42.4-2.4-2.4
Parametrial fat weight1.42.78.90.63.02.6-1.0-1.51.5-1.51.51.5-1.61.61.6-1.5-1.51.41.5-1.51.51.5
Pavlov. Cond. lever latency0.50.72.5-1.6-0.2-0.50.90.8-0.80.8-0.8-0.80.8-0.8-0.80.80.8-0.6-0.80.8-0.8-0.8
Pavlov. Cond. magazine entry latency0.20.31.41.20.20.4-0.6-0.50.5-0.50.50.5-0.40.40.4-0.5-0.40.20.4-0.40.40.4
Pavlov. Cond. change in total contacts0.30.30.40.70.50.6-0.5-0.60.6-0.60.60.6-0.60.60.6-0.6-0.60.50.6-0.60.60.6
Pavlov. Cond. index score1.31.74.22.00.81.1-1.4-1.31.3-1.31.31.3-1.31.31.3-1.3-1.31.11.3-1.31.31.3
Pavlov. Cond. latency score0.91.22.91.70.70.9-1.1-1.11.1-1.11.11.1-1.11.11.1-1.1-1.10.91.1-1.11.11.1
Pavlov. Cond. lever contacts1.01.14.32.10.20.5-1.2-1.01.0-1.01.11.1-1.01.01.0-1.0-1.00.91.0-1.01.01.0
Pavlov. Cond. magazine entry number0.20.21.0-1.0-0.4-0.60.40.4-0.40.4-0.4-0.40.4-0.4-0.40.40.4-0.1-0.40.4-0.4-0.4
Pavlov. Cond. intertrial magazine entries0.10.10.40.2-0.5-0.4-0.7-0.30.3-0.30.40.4-0.30.30.3-0.3-0.30.50.3-0.30.30.3
Pavlov. Cond. lever-magazine prob. diff.1.82.25.82.40.91.2-1.6-1.51.5-1.51.51.5-1.41.41.4-1.5-1.41.21.4-1.41.41.4
Pavlov. Cond. response bias0.70.94.32.10.10.5-1.1-0.90.9-0.90.90.9-0.90.90.9-0.9-0.90.70.9-0.90.90.9
Pavlov. Cond. lever latency1.01.36.72.6-0.30.2-1.6-1.21.2-1.21.21.3-0.90.90.9-1.0-0.90.80.9-0.90.90.9
Pavlov. Cond. magazine entry latency0.10.10.8-0.30.90.80.20.0-0.00.0-0.0-0.0-0.10.10.1-0.1-0.1-0.00.1-0.10.10.1
Pavlov. Cond. change in total contacts0.30.42.1-1.40.80.80.90.6-0.60.6-0.7-0.70.3-0.3-0.30.40.3-0.4-0.30.3-0.3-0.3
Pavlov. Cond. index score0.91.14.3-2.10.50.11.51.1-1.11.1-1.2-1.20.9-0.9-0.90.90.9-0.9-0.90.9-0.9-0.9
Pavlov. Cond. latency score0.60.73.1-1.80.60.31.30.9-0.90.9-0.9-0.90.6-0.6-0.60.70.6-0.7-0.60.6-0.6-0.6
Pavlov. Cond. lever contacts1.72.311.2-3.30.3-0.22.01.6-1.61.6-1.7-1.71.3-1.3-1.31.31.3-1.1-1.31.3-1.3-1.3
Pavlov. Cond. magazine entry number0.30.30.70.7-0.2-0.1-0.8-0.60.6-0.60.60.6-0.50.50.5-0.5-0.50.60.5-0.50.50.5
Pavlov. Cond. intertrial magazine entries0.30.32.8-1.7-0.3-0.80.40.5-0.50.5-0.5-0.50.4-0.4-0.40.40.4-0.1-0.40.4-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.0.60.83.6-1.90.60.31.30.9-0.90.9-1.0-1.00.7-0.7-0.70.70.7-0.7-0.70.7-0.7-0.7
Pavlov. Cond. response bias1.72.410.3-3.20.4-0.12.01.6-1.71.6-1.7-1.71.3-1.3-1.31.31.3-1.2-1.31.3-1.3-1.3
Time in closed arm before self-admin1.82.18.32.9-1.5-1.0-2.4-1.41.4-1.41.51.5-1.01.01.0-1.1-1.21.11.0-1.01.01.0
Time in closed arm after self-admin0.50.51.4-0.1-1.2-0.90.60.7-0.80.7-0.7-0.70.7-0.7-0.70.70.8-0.7-0.70.7-0.7-0.7
Time in open arm before self-admin1.11.21.60.0-1.2-1.21.11.0-1.01.0-1.0-1.01.2-1.2-1.21.11.2-1.3-1.21.2-1.2-1.2
Time in open arm after self-admin1.31.45.8-0.32.42.0-0.4-1.01.0-1.01.01.0-1.11.11.1-1.0-1.11.11.1-1.11.11.1
Bone: periosteal estimation0.61.31.7-0.8-1.3-1.31.01.1-1.11.1-1.1-1.11.1-1.1-1.11.11.1-1.1-1.11.1-1.1-1.1
Bone: periosteal perimeter0.20.40.50.50.50.5-0.7-0.60.6-0.60.60.6-0.60.60.6-0.6-0.60.60.6-0.60.60.6
Bone: post-yield work0.50.71.1-0.5-1.1-1.00.70.8-0.80.8-0.8-0.80.9-0.9-0.90.80.9-0.8-0.90.9-0.9-0.9
Progressive ratio test 1 active lever presses0.10.10.80.30.90.70.1-0.30.3-0.30.20.2-0.30.30.3-0.3-0.30.60.3-0.30.30.3
Progressive ratio test 1 breakpoint0.10.10.9-0.30.90.60.70.1-0.10.1-0.2-0.10.1-0.1-0.10.10.10.2-0.10.1-0.1-0.1
Progressive ratio test 1 inactive lever presses0.50.53.7-0.71.91.80.5-0.20.2-0.20.10.1-0.50.50.5-0.4-0.40.60.4-0.40.40.4
Progressive ratio test 2 active lever presses0.80.93.61.2-1.7-1.90.30.6-0.50.6-0.5-0.50.9-0.9-0.90.80.9-0.6-0.90.9-0.9-0.9
Progressive ratio test 2 breakpoint0.70.83.11.1-1.5-1.80.30.6-0.50.6-0.5-0.50.9-0.9-0.90.80.9-0.6-0.90.9-0.9-0.9
Progressive ratio test 2 inactive lever presses0.10.10.3-0.5-0.1-0.20.10.4-0.40.4-0.4-0.30.2-0.2-0.20.30.3-0.2-0.30.3-0.3-0.3
Incentive Sensitization - Responses1.01.05.12.3-1.6-1.80.30.5-0.40.5-0.4-0.50.8-0.8-0.80.80.9-0.8-0.90.9-0.9-0.9
Incentive Sensitization - Breakpoint0.70.74.22.1-1.2-1.50.20.3-0.30.4-0.3-0.30.7-0.7-0.70.60.7-0.6-0.70.7-0.7-0.7
Sum of active levers in priming session hrs 5-60.40.32.41.6-0.10.0-0.7-0.50.5-0.50.50.6-0.50.50.5-0.5-0.50.40.5-0.50.50.5
Progressive ratio0.30.40.80.90.30.4-0.7-0.60.6-0.60.60.6-0.60.60.6-0.6-0.60.50.6-0.60.60.6
Food seeking constrained by brief footshock1.51.84.1-0.3-2.0-1.61.01.3-1.31.3-1.3-1.31.3-1.3-1.31.31.3-1.6-1.31.3-1.3-1.3
Seeking ratio, punishment vs. effort1.51.82.3-0.9-1.5-1.41.21.4-1.41.4-1.4-1.31.3-1.3-1.31.41.4-1.5-1.31.3-1.3-1.3
Retroperitoneal fat weight2.58.210.62.92.52.6-3.3-2.82.8-2.82.92.9-2.92.92.9-2.9-2.92.72.9-2.92.92.9
Reaction time number correct0.30.53.01.4-1.7-1.4-0.40.2-0.10.2-0.1-0.10.3-0.3-0.30.30.4-0.3-0.40.4-0.4-0.4
Reaction time mean minus median0.30.31.4-0.91.01.2-0.4-0.10.1-0.10.10.1-0.60.60.6-0.5-0.50.60.5-0.50.50.5
Reaction time mean minus median AUC0.40.52.8-0.81.51.7-0.4-0.20.2-0.20.20.2-0.70.70.7-0.6-0.60.70.6-0.60.60.6
Reaction time num false alarms0.20.31.41.2-0.4-0.4-0.7-0.60.6-0.60.60.6-0.40.40.4-0.4-0.40.50.4-0.40.40.4
Reaction time num false alarms AUC0.20.32.41.5-0.9-0.7-0.8-0.50.5-0.50.50.5-0.30.30.3-0.3-0.30.30.3-0.30.30.3
Reaction time trials correct on left0.30.53.01.4-1.7-1.4-0.40.2-0.10.2-0.1-0.10.3-0.3-0.30.30.4-0.3-0.40.4-0.4-0.4
Reaction time trials on left0.30.43.01.4-1.7-1.4-0.40.2-0.20.2-0.1-0.10.3-0.3-0.30.30.4-0.3-0.40.4-0.4-0.4
Reaction time mean2.02.94.10.11.81.9-1.8-1.51.5-1.51.51.5-1.81.81.8-1.8-1.82.01.7-1.71.71.7
Reaction time mean AUC1.72.33.7-0.31.91.9-1.5-1.31.3-1.31.31.3-1.61.61.6-1.6-1.61.81.5-1.51.51.5
Median of all reaction times2.53.45.20.11.91.9-1.9-1.71.7-1.81.71.7-2.02.02.0-2.0-1.92.31.9-1.91.91.9
Reaction time omissions0.10.11.2-1.1-0.1-0.20.10.1-0.10.1-0.1-0.10.1-0.1-0.10.10.10.1-0.10.1-0.1-0.1
Reaction time false alarm rate0.10.20.20.20.40.3-0.3-0.40.4-0.40.40.4-0.40.40.4-0.4-0.40.50.4-0.40.40.4
Reaction time premature initiation rate0.20.33.71.9-0.3-0.3-0.3-0.40.4-0.40.40.4-0.10.10.1-0.1-0.2-0.20.2-0.20.20.2
Reaction time premature initiations0.50.78.93.0-1.4-1.1-0.7-0.40.4-0.40.50.40.0-0.0-0.0-0.1-0.1-0.30.1-0.10.10.1
Std. dev. reaction times1.31.82.60.51.41.6-1.5-1.21.1-1.21.21.2-1.41.41.4-1.4-1.41.51.4-1.41.41.4
Reaction time trials completed0.30.43.01.4-1.7-1.4-0.40.2-0.20.2-0.1-0.10.3-0.3-0.30.30.4-0.3-0.40.4-0.4-0.4
Reaction time trials AUC0.20.32.31.4-1.5-1.2-0.50.0-0.00.00.00.00.2-0.2-0.20.10.2-0.1-0.20.2-0.2-0.2
Run reversals in cocaine runway, females0.30.31.50.8-1.2-1.1-0.8-0.40.4-0.40.40.4-0.10.10.1-0.1-0.10.30.1-0.10.10.1
Run reversals in cocaine runway, males2.72.63.00.91.61.7-1.5-1.61.6-1.61.61.6-1.61.61.6-1.7-1.61.71.6-1.61.61.6
Latency to leave start box in cocaine runway0.30.30.9-0.30.20.10.90.5-0.60.5-0.6-0.60.5-0.5-0.50.50.6-0.6-0.60.6-0.6-0.6
Latency to leave start box in cocaine runway, F0.10.10.2-0.5-0.1-0.00.30.3-0.30.3-0.3-0.30.2-0.2-0.20.20.4-0.2-0.30.3-0.3-0.3
Latency to leave start box in cocaine runway, M0.40.41.0-0.30.1-0.11.00.7-0.70.7-0.7-0.70.6-0.6-0.60.60.6-0.7-0.60.6-0.6-0.6
Std. dev. time between licks in bursts0.80.91.0-0.9-0.9-0.81.01.0-1.01.0-1.0-1.01.0-1.0-1.01.01.0-1.0-1.01.0-1.0-1.0
Total sessions with >9 infusions0.60.63.0-0.51.71.70.1-0.50.5-0.50.40.4-0.70.70.7-0.7-0.61.00.6-0.60.60.6
Short access day 1 total inactive lever presses0.50.53.41.8-0.9-0.8-1.2-0.60.6-0.60.70.7-0.40.40.4-0.5-0.40.40.4-0.40.40.4
Short access day 10 total inactive lever presses0.40.42.6-1.31.51.60.4-0.0-0.0-0.0-0.0-0.0-0.30.30.3-0.3-0.50.20.4-0.40.40.4
Short access day 1 total infusions0.60.64.31.8-2.1-1.4-0.20.2-0.20.2-0.1-0.10.4-0.4-0.40.30.4-0.2-0.40.4-0.4-0.4
Short access day 10 total infusions0.20.33.92.00.20.40.70.1-0.10.1-0.1-0.10.1-0.1-0.10.10.2-0.1-0.20.2-0.2-0.2
Short access total infusions0.60.71.51.2-1.2-0.90.70.7-0.70.7-0.7-0.60.7-0.7-0.70.70.8-0.7-0.80.8-0.8-0.8
Short access day 1 locomotion1.61.72.3-0.6-1.4-0.81.51.5-1.51.5-1.5-1.51.2-1.2-1.21.21.3-1.2-1.31.3-1.3-1.3
Short access day 10 total locomotion1.21.37.7-2.82.72.71.30.4-0.40.4-0.5-0.5-0.30.30.3-0.2-0.20.60.2-0.20.20.2
Short access total locomotion0.60.74.3-2.11.61.51.20.6-0.60.5-0.6-0.60.1-0.1-0.10.20.20.1-0.20.2-0.2-0.2
One hour access (0.3 mA shock)0.20.22.21.50.40.20.80.2-0.20.2-0.2-0.20.3-0.3-0.30.30.3-0.4-0.30.3-0.3-0.3
Compulsive drug intake1.11.13.00.3-0.7-0.61.21.1-1.11.1-1.1-1.11.0-1.0-1.01.10.9-1.7-0.90.9-0.9-0.9
One hour access (shock baseline)0.60.73.80.81.91.80.3-0.50.5-0.50.40.5-0.70.70.7-0.7-0.61.00.6-0.60.60.6
Social response proportion1.92.16.52.60.40.6-1.6-1.51.5-1.51.61.6-1.31.31.3-1.4-1.31.21.3-1.31.31.3
Social responses0.00.10.30.50.30.4-0.1-0.30.3-0.30.30.2-0.20.20.2-0.2-0.20.20.2-0.20.20.2
Social time0.00.00.1-0.1-0.3-0.1-0.20.2-0.20.2-0.1-0.10.1-0.1-0.10.00.1-0.1-0.10.1-0.1-0.1
Soleus weight1.23.44.3-1.1-2.1-2.01.61.8-1.81.8-1.8-1.81.9-1.9-1.91.91.9-2.0-1.91.9-1.9-1.9
Bone: stiffness0.50.80.9-0.9-0.7-0.80.90.9-0.90.9-0.9-0.90.9-0.9-0.90.90.9-0.9-0.90.9-0.9-0.9
Tibialis anterior weight0.31.03.60.1-1.9-1.70.50.8-0.80.8-0.8-0.81.0-1.0-1.00.91.0-0.9-1.01.0-1.0-1.0
Time to tail flick, vehicle, before self-admin0.40.40.8-0.1-0.7-0.50.90.7-0.70.7-0.7-0.70.6-0.6-0.60.60.6-0.6-0.60.6-0.6-0.6
Time to tail flick, vehicle, after self-admin12.112.917.13.04.04.1-3.1-3.53.5-3.53.53.5-3.63.63.6-3.6-3.63.53.6-3.63.63.6
Time to tail flick, test, before self-admin0.50.53.92.0-0.7-0.3-1.2-0.50.5-0.50.60.6-0.40.40.4-0.5-0.50.30.4-0.40.40.4
Time to tail flick, test, after self-admin1.41.58.52.90.00.3-1.4-1.21.2-1.11.21.2-1.01.01.0-1.1-1.01.01.0-1.01.01.0
Delta time to tail flick, vehicle, before/after SA11.511.411.72.83.33.4-3.4-3.43.4-3.43.43.4-3.43.43.4-3.4-3.43.33.4-3.43.43.4
Delta time to tail flick, test, before/after SA0.40.31.11.00.20.2-0.5-0.60.6-0.60.60.6-0.50.50.5-0.5-0.50.60.5-0.50.50.5
Tibia length0.20.62.7-0.51.71.3-0.4-0.70.7-0.70.70.6-0.70.70.7-0.7-0.70.80.7-0.70.70.7
Ambulatory time before self-admin0.20.22.4-1.50.40.4-0.0-0.00.0-0.10.00.1-0.20.20.2-0.2-0.20.40.2-0.20.20.2
Ambulatory time after self-admin2.62.94.1-2.0-1.7-1.91.31.7-1.71.7-1.7-1.71.7-1.7-1.71.71.6-1.6-1.71.7-1.7-1.7
Bone: tissue strength1.71.72.2-1.0-1.5-1.41.11.3-1.31.3-1.3-1.31.3-1.3-1.31.31.3-1.2-1.31.3-1.3-1.3
Total heroin consumption0.20.22.21.50.40.4-0.4-0.40.4-0.40.40.4-0.30.30.3-0.3-0.50.10.3-0.30.30.3
Bone: trabecular number0.10.21.31.1-1.1-0.8-0.6-0.20.2-0.10.20.2-0.10.10.1-0.1-0.10.10.1-0.10.10.1
Bone: trabecular spacing0.30.40.5-0.3-0.5-0.50.70.7-0.70.7-0.7-0.70.7-0.7-0.70.70.7-0.7-0.70.7-0.7-0.7
Bone: trabecular thickness0.10.21.0-0.91.00.8-0.0-0.20.2-0.20.20.1-0.30.30.3-0.3-0.30.30.3-0.30.30.3
Bone: trabecular tissue density0.40.51.5-1.20.1-0.11.00.7-0.70.7-0.7-0.80.7-0.7-0.70.70.7-0.7-0.70.7-0.7-0.7
Water consumed over 24 hours0.50.62.31.0-1.4-1.50.30.4-0.40.4-0.4-0.40.8-0.8-0.80.70.7-0.8-0.80.8-0.8-0.8
Number of responses in last shaping day1.21.33.60.01.91.9-0.5-0.90.8-0.90.80.8-1.21.21.2-1.2-1.01.41.0-1.01.01.0