Hub : Genes

Spats1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Spats1 0.19 0.1 8.2e-03 0.07 0.02 0.05 0.08 7.3e-03 9.5e-02 2.7e-02 5.8e-03
2 PL mRNA stability Spats1 0.14 0.06 8.6e-13 0.08 0.1 0.11 0.1 4.0e-09 1.7e-11 5.0e-12 5.2e-11
3 pVTA gene expression Spats1 0.12 0.07 1.4e-03 0.04 0.06 0.04 0.02 6.6e-03 1.1e-03 9.5e-03 3.1e-02
4 Brain mRNA stability Spats1 0.1 0.05 2.8e-06 0.08 0.06 0.04 0.06 1.2e-07 5.3e-06 1.9e-04 1.4e-06
5 BLA mRNA stability Spats1 0.17 0.08 1.3e-06 0.04 0.07 0.05 0.07 1.9e-03 7.7e-05 1.3e-03 1.4e-04
6 Brain gene expression Spats1 0.44 0.15 0.0e+00 0.27 0.33 0.33 0.34 7.1e-25 5.9e-32 7.0e-32 1.6e-32
7 LHb mRNA stability Spats1 0.24 0.13 7.3e-03 0.03 0.04 0.06 -0.01 5.7e-02 4.4e-02 1.4e-02 7.3e-01
8 PL gene expression Spats1 0.1 0.05 7.4e-08 0.07 0.06 0.05 0.06 2.7e-08 2.0e-07 2.2e-06 4.5e-07
9 OFC mRNA stability Spats1 0.19 0.1 2.7e-03 0.06 0.1 0.06 0 1.6e-02 2.2e-03 1.3e-02 3.2e-01
10 Adipose gene expression Spats1 0.08 0.04 1.0e-07 0.06 0.06 0.05 0.06 1.0e-07 4.0e-07 1.7e-06 3.5e-07
11 NAcc gene expression Spats1 0.06 0.03 2.5e-06 0.07 0.06 0.06 0.04 1.5e-08 3.1e-07 3.8e-07 1.7e-05
12 BLA gene expression Spats1 0.11 0.07 5.6e-04 0.03 0.04 0.05 0.05 1.6e-02 5.6e-03 1.1e-03 1.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.61.02.01.0-0.8-1.4-0.20.7-1.41.10.70.81.41.40.5
Area under the delay curve2.62.77.2-0.62.4-1.42.7-2.30.21.31.3-1.4-1.1-1.41.9
BMI with tail2.47.618.1-2.81.64.3-0.4-1.23.80.7-3.7-2.2-3.3-3.2-2.7
BMI without tail7.014.330.2-4.01.75.4-1.2-1.45.20.4-5.5-2.4-4.4-4.3-4.4
Body weight0.83.58.7-1.8-0.42.6-2.10.72.40.9-2.9-0.3-1.3-1.1-2.9
Weight adjusted by age0.40.41.3-0.40.3-0.50.8-0.5-0.20.91.0-0.4-0.10.11.2
Bone surface1.73.08.61.5-0.6-2.90.80.4-2.41.62.01.02.11.91.8
Bone volume1.22.15.11.3-0.7-2.30.40.5-2.01.31.60.81.81.71.4
Breakpoint value in progressive ratio session0.50.52.0-0.20.7-0.31.4-0.9-0.10.40.8-0.4-0.5-0.31.1
Number of licking bursts0.60.71.70.6-1.20.3-1.31.3-0.3-0.2-0.70.80.50.8-1.0
Context. condit. distance diff. score1.21.43.4-1.70.21.6-0.8-0.21.51.1-1.9-0.6-1.0-0.9-1.3
Locomotion velocity, session 11.11.22.5-1.01.2-0.81.6-1.50.21.40.8-1.0-0.8-0.71.4
Locomotion distance, session 10.50.72.0-1.30.40.70.4-0.90.61.4-1.1-0.6-0.7-0.5-0.1
Locomotion velocity, session 22.52.97.2-2.71.01.70.3-1.32.11.6-2.2-1.2-2.0-1.9-1.1
Locomotion distance, session 21.01.42.9-1.71.01.00.9-1.31.11.5-1.3-1.1-1.2-1.2-0.2
Locomotion velocity, session 31.01.13.0-1.71.10.71.2-1.51.00.3-0.7-0.8-1.1-1.30.1
Locomotion distance, session 30.40.41.1-1.00.8-0.10.9-0.90.50.4-0.1-0.6-0.4-0.60.3
Stereotopy head waving bouts, day 30.30.30.60.7-0.7-0.3-0.80.8-0.40.8-0.10.30.50.6-0.3
Stereotopy head waving duration, day 30.20.30.9-0.20.20.9-0.1-0.20.50.6-0.6-0.7-0.6-0.4-0.2
Locomotion velocity, session 70.30.41.40.20.1-0.90.6-0.3-0.71.20.50.00.50.30.8
Locomotion distance, session 70.60.71.7-0.91.10.21.2-1.30.40.80.2-1.0-0.7-0.90.8
Stereotopy head waving bouts, day 70.40.42.2-0.2-0.20.6-0.70.30.31.5-1.1-0.40.0-0.1-0.7
Stereotopy head waving duration, day 70.30.40.90.4-0.70.1-0.90.8-0.30.7-0.70.30.70.5-0.7
Locomotion velocity, session 80.30.32.2-0.2-0.2-0.50.4-0.1-0.61.5-0.20.30.60.40.4
Locomotion distance, session 81.32.05.8-2.40.81.50.3-1.21.51.5-1.9-1.0-1.3-1.4-0.7
Degree of sensitization distance0.30.30.5-0.50.60.30.5-0.70.40.50.1-0.7-0.7-0.60.4
Degree of sensitization stereotypy0.40.43.0-0.50.10.2-0.2-0.10.31.7-1.0-0.4-0.1-0.2-0.5
Conditioned locomotion0.80.92.8-0.61.2-0.81.7-1.4-0.00.40.9-0.7-0.4-0.61.3
Cocaine response after cond. corrected1.01.14.11.3-0.9-0.1-0.50.8-1.0-2.01.50.60.81.00.7
Cocaine response after cond. not corrected1.11.23.01.5-0.8-0.4-0.30.7-1.2-1.61.70.50.81.11.0
Cocaine response before conditioning0.50.61.50.10.5-0.91.1-0.7-0.61.20.8-0.40.10.11.2
Saline control response0.30.41.9-0.50.6-0.51.0-0.7-0.11.4-0.2-0.1-0.1-0.20.5
Bone: connectivity density0.81.33.41.3-0.7-1.9-0.10.7-1.50.61.20.81.51.40.7
Bone: cortical apparent density0.20.31.40.3-0.1-1.0-0.30.4-0.41.20.10.20.80.6-0.0
Bone: cortical area0.10.21.0-0.4-0.4-0.3-0.0-0.0-0.41.0-0.20.20.70.60.2
Bone: cortical porosity0.70.81.6-0.90.31.3-0.4-0.11.3-1.1-1.2-0.2-0.8-0.8-1.2
Bone: cortical porosity0.60.72.4-0.90.51.3-0.0-0.41.1-1.6-0.6-0.4-0.8-0.8-0.6
Bone: cortical thickness0.50.82.7-1.60.30.70.0-0.60.91.4-1.3-0.6-0.4-0.5-0.6
Bone: cortical thickness0.50.51.40.5-0.9-0.7-0.90.8-0.60.0-0.10.81.20.8-0.6
Bone: cortical tissue density0.20.31.20.3-0.1-0.9-0.30.4-0.41.10.10.20.80.5-0.0
Condit. Reinf. active minus inactive responses0.91.01.91.2-1.0-0.3-0.10.5-1.4-0.91.20.61.31.31.2
Condit. Reinf. active-inactive response ratio1.31.44.61.5-1.1-0.0-0.71.0-1.1-2.11.40.71.41.20.7
Condit. Reinf. active responses0.40.51.10.5-1.00.0-0.10.4-1.0-0.60.60.71.01.00.7
Condit. Reinf. inactive responses0.30.41.6-0.9-0.20.60.0-0.10.51.1-1.30.2-0.4-0.2-0.6
Incentive salience index mean0.20.20.60.2-0.70.30.10.1-0.6-0.80.30.40.70.60.6
Condit. Reinf. lever presses0.40.52.1-1.10.01.10.1-0.30.80.3-1.5-0.0-0.5-0.6-0.8
Condit. Reinf. active minus inactive responses0.30.41.20.50.1-0.10.4-0.2-0.6-0.91.1-0.30.40.41.0
Condit. Reinf. active-inactive response ratio0.40.41.10.9-0.40.1-0.20.3-0.7-0.81.0-0.10.50.70.8
Condit. Reinf. active responses0.40.61.5-0.20.9-0.61.2-1.1-0.2-0.11.0-0.7-0.1-0.31.2
Condit. Reinf. inactive responses0.70.82.0-0.81.3-1.01.4-1.30.41.10.2-0.6-0.6-0.80.6
Condit. Reinf. lever presses0.10.20.3-0.60.50.30.3-0.50.50.3-0.5-0.5-0.4-0.4-0.2
Condit. Reinf. lever reinforcers received0.40.51.4-0.30.8-0.41.2-1.0-0.2-0.30.9-0.6-0.1-0.31.2
Conditioned reinforcement - actives0.70.72.0-0.90.70.31.3-1.20.10.30.6-1.0-0.7-0.51.4
Conditioned reinforcement - inactives0.30.30.7-0.30.50.60.3-0.70.40.00.1-0.8-0.9-0.60.6
Conditioned locomotion0.00.00.2-0.4-0.40.3-0.10.20.20.1-0.00.10.00.20.0
Patch foraging indifference point 0 sec0.61.02.2-1.11.20.50.1-0.61.51.2-1.0-1.3-1.1-1.1-0.7
Patch foraging indifference point AUC2.52.95.7-1.92.21.02.0-2.41.40.4-0.1-2.3-1.8-1.91.0
Delay disc. indifference point, 0s delay1.51.64.40.51.7-0.21.8-1.5-0.40.91.3-1.90.0-0.52.1
Delay disc. indifference point, 16s delay1.01.12.4-0.01.5-1.51.4-1.2-0.10.71.4-0.4-0.3-0.81.3
Delay disc. indifference point, 2s delay1.51.74.9-0.12.0-0.42.2-1.90.10.20.8-1.5-1.0-1.21.5
Delay disc. indifference point, 24s delay1.01.02.3-1.51.3-0.51.0-1.21.10.9-0.3-0.5-1.1-1.00.0
Delay disc. indifference point, 4s delay2.82.96.6-0.92.60.12.5-2.50.80.80.4-2.1-1.7-2.01.4
Delay disc. indifference point, 8s delay2.22.26.6-0.31.7-1.82.6-1.9-0.41.01.7-0.8-0.5-0.62.2
Indifference point function ln k0.30.41.50.3-0.20.5-1.20.80.50.0-0.50.30.20.0-1.1
Indifference point function log k0.30.41.50.3-0.20.5-1.20.80.50.0-0.50.30.20.0-1.1
Patch foraging total patch changes 0 sec0.81.32.9-1.21.40.70.1-0.81.71.3-1.0-1.5-1.2-1.3-0.7
Patch foraging total patch changes 12 sec2.63.36.4-2.51.90.91.1-1.82.12.3-1.7-1.9-2.0-2.0-0.6
Patch foraging total patch changes 18 sec0.50.71.3-0.71.1-0.41.0-1.20.30.70.6-1.1-0.5-0.70.9
Patch foraging total patch changes 24 sec2.22.64.7-2.21.80.81.0-1.72.01.7-1.2-1.8-1.8-2.0-0.4
Patch foraging total patch changes 6 sec1.72.54.0-2.01.61.10.7-1.42.01.7-1.6-1.8-1.8-1.8-0.7
Patch foraging time to switch 0 sec2.84.48.42.5-2.1-2.9-0.61.9-2.7-0.41.72.92.22.30.5
Patch foraging water rate 0 sec2.84.510.1-2.72.51.91.2-2.32.42.0-1.3-3.2-2.0-2.20.1
Patch foraging water rate 12 sec2.94.410.9-2.71.53.30.1-1.42.72.0-2.1-2.5-1.7-2.1-0.9
Patch foraging water rate 18 sec1.62.14.2-1.81.11.7-0.2-0.72.11.6-1.7-1.5-1.1-1.5-1.2
Patch foraging water rate 24 sec2.02.88.8-1.50.93.0-1.3-0.22.30.6-2.4-1.6-0.8-1.5-1.9
Patch foraging water rate 6 sec0.71.12.4-1.41.21.30.8-1.21.00.9-0.7-1.5-0.6-1.00.2
Seeking ratio, delayed vs. immediate footshock0.00.00.3-0.1-0.10.10.30.1-0.10.5-0.00.00.20.20.1
Distance traveled before self-admin0.50.51.9-0.1-0.40.8-0.90.50.50.0-1.40.2-0.1-0.1-1.4
Distance traveled after self-admin0.20.21.5-0.20.11.2-0.3-0.10.4-0.3-0.5-0.5-0.1-0.1-0.0
Extensor digitorum longus weight0.10.41.3-0.2-0.51.1-1.10.50.40.2-0.8-0.00.10.1-0.8
Bone: elastic displacement0.30.40.90.1-0.7-0.2-0.90.7-0.2-0.1-0.61.00.50.3-0.9
Bone: elastic work1.82.35.20.5-2.10.2-2.31.9-0.5-1.1-1.32.11.41.0-2.0
Bone: endosteal estimation1.22.65.12.3-1.3-1.7-0.41.2-2.2-0.71.71.42.12.00.9
Bone: endosteal perimeter1.02.24.51.7-1.1-1.70.10.8-2.1-0.21.71.22.02.01.4
Epididymis fat weight0.92.16.7-1.2-0.81.6-2.11.11.9-0.1-1.90.3-0.7-0.8-2.6
Delta time in closed arm before/after self-admin0.40.30.9-0.70.60.40.0-0.20.90.3-0.6-0.3-0.7-0.8-0.8
Delta time in open arm before/after self-admin1.11.12.8-0.81.70.21.5-1.60.5-0.3-0.0-1.3-0.8-1.20.8
Diff in mean of infusions in LGA sessions0.40.41.01.0-0.80.1-0.20.7-0.7-0.80.70.60.60.90.3
Delay discount exponential model param2.82.97.80.9-2.41.5-2.82.4-0.4-1.4-1.21.41.31.5-1.8
Extinction: sum of active levers before priming0.20.20.50.10.1-0.70.6-0.2-0.5-0.60.60.30.50.40.6
Active lever presses in extinction session 60.20.21.0-1.00.30.40.5-0.60.40.10.2-0.2-0.5-0.60.5
Bone: final force0.20.30.8-0.3-0.80.1-0.90.6-0.20.0-0.40.50.70.7-0.5
Bone: final moment0.10.20.3-0.5-0.50.2-0.60.3-0.00.4-0.50.10.50.4-0.4
Food consumed during 24 hour testing period0.30.43.0-0.20.40.20.3-0.20.31.7-1.0-0.3-0.3-0.2-0.3
Glucose1.11.74.6-1.20.42.1-0.8-0.31.71.2-1.6-1.1-1.6-1.3-1.2
Heart weight0.71.04.10.9-0.4-2.00.00.5-1.00.91.30.71.01.10.7
Delay discount hyperbolic model param2.93.18.60.8-2.51.4-2.92.5-0.3-1.2-1.21.51.31.6-2.0
Intermittent access intake day 1-15 change0.30.30.70.8-0.7-0.1-0.30.5-0.6-0.10.70.40.60.70.6
Intermittent access intake escalation1.11.12.11.3-1.1-0.5-0.61.0-1.2-0.31.21.01.41.50.7
Intermittent access intake escalation 20.20.20.6-0.40.2-0.70.4-0.30.10.80.60.10.20.10.6
Intermitt. access day 1 inactive lever presses1.71.83.71.5-1.90.5-1.51.7-1.0-1.8-0.31.51.21.3-0.8
Intermitt. access day 15 inactive lever presses0.30.30.80.9-0.30.7-0.60.50.10.0-0.8-0.3-0.1-0.2-0.8
Intermitt. access escalation Index0.80.72.8-0.50.51.7-0.4-0.11.1-0.5-1.0-0.6-0.7-0.6-0.9
Intermittent access day 1 total infusions0.10.10.3-0.5-0.10.3-0.40.10.4-0.1-0.40.2-0.3-0.3-0.5
Intermittent access day 15 total infusions0.60.61.30.8-1.1-0.2-0.81.1-0.8-0.40.61.10.91.00.1
Intermittent access terminal intake (last 3 days)0.10.20.50.1-0.7-0.1-0.50.5-0.3-0.10.30.70.20.30.0
Intermittent access total infusions0.00.00.1-0.30.00.20.1-0.00.1-0.10.20.1-0.3-0.20.2
Intermittent access day 1 locomotion0.30.30.6-0.2-0.50.7-0.80.60.3-0.5-0.50.50.10.0-0.8
Intermittent access day 15 total locomotion0.30.30.7-0.1-0.5-0.8-0.00.3-0.5-0.70.70.80.60.50.3
Intermittent access total locomotion0.20.20.60.1-0.1-0.80.30.1-0.4-0.20.80.40.30.20.5
Intermittent access standard deviation0.60.61.90.4-0.6-1.4-0.10.5-0.70.31.11.00.80.80.6
Left kidney weight0.61.73.3-1.81.30.60.4-0.91.71.8-1.4-1.0-1.4-1.3-0.8
Right kidney weight1.02.98.3-1.82.00.61.0-1.51.92.9-1.2-2.0-1.7-1.7-0.2
Cocaine induced anxiety0.50.51.71.3-0.80.2-0.50.7-0.8-1.30.50.40.50.50.3
Post-drug Anxiety3.74.18.12.9-2.4-1.5-1.72.3-2.3-1.31.32.32.32.3-0.0
Baseline Anxiety2.22.46.11.3-1.6-2.5-0.81.5-1.80.41.22.01.81.90.2
Tail length0.72.15.8-1.7-0.31.4-1.70.31.80.6-2.40.1-1.1-0.9-2.4
Length with tail0.72.44.50.5-2.1-1.6-2.12.1-1.01.10.31.91.62.0-0.8
Length without tail3.16.813.22.6-2.7-3.1-1.22.5-3.20.42.62.63.33.61.3
Times rat made contact with spout0.20.30.7-0.60.30.6-0.2-0.10.80.3-0.4-0.3-0.8-0.6-0.5
Lifetime Intake0.10.10.30.00.0-0.10.3-0.1-0.2-0.10.60.1-0.2-0.00.5
Liver weight, left0.50.82.5-1.60.90.70.5-1.01.20.3-0.5-0.6-1.3-1.1-0.3
Liver weight, right0.81.43.00.3-1.70.9-1.61.4-0.3-1.7-0.81.50.71.2-1.1
Locomotor activity1.21.95.20.1-1.70.3-2.31.90.1-0.4-1.41.41.11.1-2.1
Locomotor testing distance1.01.64.8-0.0-1.50.1-2.21.70.10.4-1.41.21.11.0-1.9
Locomotor testing rearing0.50.82.9-0.5-0.81.7-1.40.70.8-0.4-1.3-0.10.20.1-1.3
Locomotion in novel chamber1.92.45.7-1.81.90.42.4-2.21.10.6-0.2-1.4-2.0-1.70.9
Locomotion in novel chamber post-restriction1.72.07.3-0.71.2-1.62.2-1.5-0.60.52.2-0.50.00.12.7
Fecal boli incidents, locomotor time 10.40.40.9-0.90.80.10.9-1.00.30.70.0-0.9-0.5-0.60.5
Change in fecal boli incidents, locomotor task0.40.41.40.70.4-0.51.0-0.3-0.5-0.61.00.1-0.1-0.11.2
Time >=10cm from walls, locomotor time 10.10.10.3-0.20.60.40.2-0.50.30.3-0.0-0.6-0.4-0.20.3
Bouts of movement, locomotor time 10.91.01.5-1.11.20.80.9-1.01.20.9-0.5-1.2-1.2-0.90.1
Total resting periods, locomotor time 10.40.51.0-0.60.70.90.4-0.60.80.9-0.4-1.0-0.8-0.50.0
Rest time, locomotor task time 11.51.63.8-0.31.80.41.9-1.70.40.90.6-1.9-1.3-1.01.5
Distance moved, locomotor task time 10.30.40.9-0.5-0.40.8-1.00.20.6-0.9-0.50.50.1-0.3-0.8
Vertical activity count, locomotor time 10.60.62.2-0.1-1.00.1-0.90.70.1-1.5-0.41.40.30.3-0.9
Time >=10cm from walls, locomotor time 20.10.10.20.5-0.30.3-0.40.4-0.2-0.30.10.20.20.4-0.1
Bouts of movement, locomotor time 21.01.12.6-1.61.20.30.3-1.11.21.3-1.0-1.0-0.7-1.3-0.4
Total resting periods, locomotor time 20.70.81.8-1.31.00.30.2-0.81.11.1-1.0-0.8-0.5-1.1-0.5
Rest time, locomotor task time 20.50.61.8-0.21.1-0.11.3-0.90.21.00.0-1.0-0.9-0.60.6
Distance moved, locomotor task time 20.20.21.10.2-0.40.4-0.80.3-0.1-1.00.20.40.50.3-0.1
Vertical activity count, locomotor time 20.91.01.80.9-0.9-0.9-0.50.7-1.0-1.31.21.21.21.10.7
Light reinforcement 10.20.41.7-1.00.20.7-0.0-0.20.80.4-1.3-0.2-0.2-0.3-0.8
Light reinforcement 20.40.51.20.1-0.70.7-0.90.80.2-0.7-1.10.60.50.6-1.0
Bone: marrow area1.22.75.02.2-1.4-1.8-0.41.3-2.2-0.61.71.52.22.10.9
Bone: maximum diameter0.40.72.00.30.2-1.01.0-0.5-1.01.20.9-0.20.80.71.4
Bone: maximum force0.71.22.40.5-1.5-0.1-1.41.4-0.7-0.6-0.51.31.41.3-1.0
Bone: maximum moment0.50.81.50.3-1.20.1-1.21.1-0.5-0.3-0.71.01.21.0-0.9
Mean time between licks in bursts0.91.22.81.5-0.5-1.50.00.6-1.3-1.71.10.91.21.20.5
Mean num. licks in bursts0.91.02.4-0.91.5-0.01.3-1.40.70.50.6-1.2-1.0-1.10.9
Cd content in liver0.60.61.50.90.2-0.80.9-0.3-1.0-0.61.10.20.80.41.2
Co content in liver0.50.63.00.1-0.01.4-0.30.10.5-1.7-0.90.1-0.3-0.7-0.8
Cu content in liver0.20.31.0-0.10.5-0.61.0-0.6-0.30.20.6-0.20.0-0.00.9
Fe content in liver0.50.62.3-1.50.60.00.6-0.90.90.3-0.4-0.3-1.0-0.9-0.2
K content in liver2.32.34.81.2-1.9-1.3-1.82.0-1.2-0.70.12.21.71.7-1.1
Mg content in liver0.30.31.2-0.4-0.2-0.9-0.30.2-0.11.1-0.30.60.30.2-0.5
Mn content in liver0.10.10.50.70.30.10.00.10.00.30.1-0.60.2-0.00.0
Na content in liver0.40.41.7-0.8-0.10.2-0.4-0.00.41.3-1.20.1-0.5-0.3-0.9
Rb content in liver1.51.97.50.9-0.5-2.70.40.4-1.80.91.41.51.71.21.0
Se content in liver2.02.55.9-1.52.1-0.41.9-1.91.12.4-0.2-1.8-1.5-1.50.7
Sr content in liver0.30.30.80.9-0.60.7-0.50.5-0.3-0.7-0.20.10.40.4-0.2
Zn content in liver1.82.04.8-0.61.7-1.32.2-1.8-0.21.81.3-1.3-0.4-0.62.0
Bone: minimum diameter0.91.73.51.2-1.1-1.5-0.10.8-1.90.01.41.11.81.81.1
Time in familiar zone, hab. session 13.53.25.4-2.31.61.60.5-1.42.22.0-2.3-1.4-2.0-2.1-1.2
Time in novel zone, hab. session 12.12.14.72.2-0.9-1.0-0.21.0-1.8-1.72.10.81.61.51.2
Total zone transitions, hab. session 10.81.13.1-1.30.31.7-0.1-0.61.20.8-1.7-0.7-1.1-0.8-0.9
Total locomotion distance, hab. session 10.71.03.6-1.20.21.90.3-0.61.10.3-1.4-0.9-1.2-0.7-0.5
Locomotion velocity, hab. session 10.40.62.8-1.0-0.21.70.1-0.30.8-0.0-1.1-0.5-0.9-0.3-0.3
Time in familiar zone, hab. session 20.50.51.20.5-0.8-0.5-1.01.0-0.3-0.4-0.11.10.50.5-0.8
Time in novel zone, hab. session 21.01.02.6-0.81.21.11.0-1.20.90.6-0.3-1.6-1.0-1.00.5
Total zone transitions, hab. session 20.30.41.20.4-1.00.4-1.10.9-0.2-0.0-0.50.50.40.8-0.7
Total locomotion distance, hab. session 20.20.20.7-0.0-0.60.8-0.60.50.20.4-0.7-0.0-0.10.3-0.5
Locomotion velocity, hab. session 20.10.20.50.2-0.70.3-0.50.6-0.10.3-0.30.20.20.6-0.3
Novel to familiar place preference ratio0.00.00.10.2-0.20.2-0.30.2-0.10.1-0.10.10.10.2-0.1
Novelty place preference0.10.10.2-0.1-0.30.1-0.50.30.10.4-0.50.20.00.1-0.5
Time in novel zone, NPP test0.10.10.6-0.30.10.3-0.30.00.40.8-0.6-0.2-0.3-0.2-0.5
Total zone transitions, NPP test0.50.71.8-1.30.11.0-0.1-0.40.91.2-1.3-0.6-0.7-0.7-0.7
Total locomotion distance, NPP test0.40.51.5-1.0-0.21.2-0.3-0.10.70.6-1.2-0.5-0.5-0.4-0.6
Locomotion velocity, NPP test0.40.51.1-0.7-1.10.9-1.00.70.20.0-1.00.40.20.3-0.9
Intraocular pressure1.11.59.41.9-0.90.7-0.50.8-1.0-3.10.80.40.60.90.3
Delta distance traveled before/after self-admin0.20.20.70.10.00.7-0.1-0.1-0.1-0.50.6-0.40.10.10.8
Delta ambulatory time before/after self-admin0.40.41.10.6-0.50.4-0.30.4-0.6-0.91.00.10.70.71.0
Parametrial fat weight2.44.613.3-1.90.23.4-1.60.12.80.9-3.7-1.1-1.7-1.7-2.9
Pavlov. Cond. lever latency1.01.23.21.8-0.8-0.6-0.81.2-1.1-1.61.20.81.11.20.2
Pavlov. Cond. magazine entry latency0.60.71.5-0.70.90.41.1-1.10.41.2-0.1-1.1-0.6-0.80.7
Pavlov. Cond. change in total contacts0.70.81.6-0.90.70.90.8-0.90.81.3-1.0-1.0-0.8-0.80.0
Pavlov. Cond. index score0.81.02.6-1.30.80.70.9-1.20.71.6-0.7-1.0-0.9-1.00.3
Pavlov. Cond. latency score0.81.02.7-1.40.80.41.1-1.20.61.7-0.6-1.0-0.8-1.00.4
Pavlov. Cond. lever contacts0.81.02.6-1.60.50.90.5-0.81.11.1-1.4-0.6-1.0-1.1-0.5
Pavlov. Cond. magazine entry number0.40.51.20.5-0.6-0.7-0.90.9-0.3-1.10.11.00.60.6-0.7
Pavlov. Cond. intertrial magazine entries0.10.20.8-0.50.10.20.0-0.00.50.1-0.90.2-0.3-0.1-0.7
Pavlov. Cond. lever-magazine prob. diff.0.60.81.5-1.10.70.80.9-1.10.71.2-0.6-1.0-0.8-0.90.4
Pavlov. Cond. response bias0.70.81.4-1.20.61.10.5-0.81.01.0-1.0-0.9-1.0-1.0-0.2
Pavlov. Cond. lever latency0.20.20.6-0.10.8-0.30.6-0.50.20.7-0.0-0.4-0.4-0.50.2
Pavlov. Cond. magazine entry latency0.30.30.7-0.7-0.60.9-0.70.20.4-0.8-0.60.1-0.2-0.2-0.7
Pavlov. Cond. change in total contacts0.30.41.2-0.5-0.60.6-1.00.50.4-1.1-0.40.30.0-0.0-0.8
Pavlov. Cond. index score0.30.41.1-0.9-0.41.0-0.70.20.7-0.2-1.1-0.0-0.4-0.2-1.0
Pavlov. Cond. latency score0.40.51.2-0.9-0.41.1-0.80.20.8-0.4-1.1-0.1-0.4-0.3-1.1
Pavlov. Cond. lever contacts0.20.20.5-0.3-0.70.2-0.70.60.1-0.5-0.30.50.30.4-0.7
Pavlov. Cond. magazine entry number0.20.20.50.70.6-0.40.7-0.3-0.20.30.6-0.30.0-0.10.7
Pavlov. Cond. intertrial magazine entries0.20.31.50.8-0.0-0.60.10.3-0.51.20.3-0.10.30.30.3
Pavlov. Cond. lever-magazine prob. diff.0.40.51.4-1.0-0.51.0-0.80.20.8-0.2-1.20.0-0.4-0.3-1.1
Pavlov. Cond. response bias0.20.30.7-0.2-0.8-0.5-0.50.5-0.4-0.10.10.70.60.6-0.3
Time in closed arm before self-admin1.11.23.31.8-1.4-0.3-1.31.4-1.1-0.80.20.81.21.3-0.2
Time in closed arm after self-admin0.90.92.31.0-0.71.5-1.51.00.4-0.8-1.0-0.10.10.2-1.3
Time in open arm before self-admin0.20.31.3-1.20.00.50.3-0.50.50.40.1-0.0-0.7-0.50.2
Time in open arm after self-admin0.70.81.7-1.21.10.51.3-1.30.4-0.60.2-0.5-0.9-1.00.7
Bone: periosteal estimation0.61.22.91.1-0.9-1.20.00.5-1.60.11.10.81.71.50.9
Bone: periosteal perimeter0.71.13.00.6-1.4-0.7-0.81.0-1.30.00.21.31.71.60.1
Bone: post-yield work0.50.71.60.5-0.90.3-1.11.1-0.0-0.7-0.90.90.80.6-1.3
Progressive ratio test 1 active lever presses1.31.43.01.2-1.60.8-1.71.6-0.6-1.7-0.21.20.81.0-0.8
Progressive ratio test 1 breakpoint1.61.73.61.4-1.80.7-1.71.7-0.8-1.90.01.40.91.1-0.7
Progressive ratio test 1 inactive lever presses0.50.51.70.5-0.90.7-1.31.00.0-0.4-0.60.50.30.3-0.9
Progressive ratio test 2 active lever presses0.20.21.50.2-0.51.2-0.60.30.1-0.8-0.20.1-0.1-0.0-0.1
Progressive ratio test 2 breakpoint0.30.32.0-0.0-0.31.4-0.60.20.4-0.5-0.5-0.1-0.4-0.3-0.3
Progressive ratio test 2 inactive lever presses0.50.61.2-0.80.80.80.4-0.90.80.4-0.2-1.0-1.1-1.10.3
Incentive Sensitization - Responses1.41.43.5-1.11.01.90.2-0.91.40.6-1.1-1.3-1.6-1.4-0.4
Incentive Sensitization - Breakpoint1.31.32.9-1.11.01.70.3-1.01.30.7-0.9-1.4-1.6-1.4-0.2
Sum of active levers in priming session hrs 5-63.73.610.5-0.41.6-2.52.8-1.9-1.01.23.0-0.7-0.1-0.03.2
Progressive ratio1.92.24.30.8-1.6-2.1-1.61.7-1.40.61.01.91.91.7-0.2
Food seeking constrained by brief footshock2.22.75.01.6-2.0-1.4-1.71.7-1.9-0.61.51.82.21.90.4
Seeking ratio, punishment vs. effort0.20.20.80.10.20.90.4-0.50.0-0.80.0-0.6-0.3-0.40.5
Retroperitoneal fat weight0.72.25.3-2.20.52.3-0.5-0.42.31.0-1.6-1.1-1.7-1.3-1.3
Reaction time number correct3.34.711.5-2.03.00.32.4-2.81.53.4-0.1-2.9-1.8-1.91.4
Reaction time mean minus median1.01.42.71.6-1.6-0.7-1.31.5-1.4-0.10.31.31.11.2-0.4
Reaction time mean minus median AUC1.62.14.92.2-1.7-1.0-1.41.8-1.7-0.40.61.51.61.6-0.2
Reaction time num false alarms0.81.02.0-1.11.4-0.31.4-1.30.81.0-0.0-1.1-1.1-0.90.6
Reaction time num false alarms AUC0.91.32.4-1.41.5-0.01.4-1.41.11.0-0.4-1.2-1.4-1.20.3
Reaction time trials correct on left3.34.711.5-2.03.00.32.4-2.81.53.4-0.1-2.9-1.8-1.91.4
Reaction time trials on left3.34.711.6-2.02.90.42.4-2.71.53.4-0.1-2.9-1.8-1.91.3
Reaction time mean2.63.67.01.8-2.6-0.0-2.62.7-1.1-2.2-0.42.41.41.6-1.7
Reaction time mean AUC2.53.36.81.8-2.6-0.1-2.62.6-1.2-1.8-0.22.31.51.6-1.5
Median of all reaction times2.43.36.61.3-2.40.3-2.62.5-0.7-2.4-0.72.31.21.3-1.9
Reaction time omissions0.20.20.7-0.4-0.60.5-0.70.50.50.2-0.70.3-0.30.0-0.8
Reaction time false alarm rate0.10.11.0-0.1-0.1-0.20.00.10.1-1.0-0.10.4-0.2-0.1-0.3
Reaction time premature initiation rate0.10.20.5-0.40.10.5-0.30.10.6-0.3-0.4-0.0-0.4-0.3-0.7
Reaction time premature initiations0.91.22.6-1.41.40.60.8-1.11.31.6-0.5-1.3-1.1-1.1-0.1
Std. dev. reaction times2.02.85.91.8-2.4-0.3-2.32.4-1.3-1.5-0.12.11.41.5-1.2
Reaction time trials completed3.34.711.6-2.02.90.42.4-2.71.53.4-0.1-2.9-1.8-1.91.3
Reaction time trials AUC3.24.711.7-2.12.90.52.3-2.71.63.4-0.2-2.9-1.8-1.91.3
Run reversals in cocaine runway, females0.80.81.70.5-1.1-0.5-1.00.9-0.8-1.00.70.91.31.00.2
Run reversals in cocaine runway, males0.60.61.7-0.50.80.8-0.1-0.41.30.4-1.0-1.0-0.6-0.6-0.8
Latency to leave start box in cocaine runway2.83.17.70.9-2.01.4-2.82.20.1-2.1-1.51.51.51.3-2.2
Latency to leave start box in cocaine runway, F1.92.14.41.0-1.70.4-2.11.8-0.4-1.8-0.71.41.71.5-1.4
Latency to leave start box in cocaine runway, M1.51.44.2-0.4-0.82.0-1.60.90.9-1.1-1.90.3-0.0-0.1-1.9
Std. dev. time between licks in bursts0.60.73.30.80.0-0.90.7-0.2-0.9-1.80.90.40.70.50.8
Total sessions with >9 infusions0.10.10.3-0.40.30.5-0.1-0.10.60.0-0.4-0.2-0.5-0.4-0.4
Short access day 1 total inactive lever presses0.60.61.1-0.90.90.80.7-0.90.90.2-0.3-0.9-1.0-1.00.2
Short access day 10 total inactive lever presses0.40.51.1-0.80.50.60.4-0.60.90.4-1.0-0.8-0.8-0.7-0.5
Short access day 1 total infusions0.40.40.9-0.40.60.90.5-0.70.6-0.2-0.3-0.8-0.9-0.80.1
Short access day 10 total infusions0.10.10.30.1-0.4-0.2-0.40.5-0.3-0.30.40.60.20.30.1
Short access total infusions0.00.00.20.20.0-0.20.10.0-0.1-0.00.40.1-0.10.10.3
Short access day 1 locomotion0.20.21.20.4-0.4-0.1-0.10.4-0.5-1.10.20.50.60.6-0.1
Short access day 10 total locomotion0.30.31.20.0-0.5-1.10.00.2-0.60.21.00.60.50.50.7
Short access total locomotion0.20.20.6-0.10.0-0.80.4-0.1-0.30.10.70.10.30.30.6
One hour access (0.3 mA shock)0.80.93.2-0.50.80.01.8-1.4-0.10.00.7-0.8-0.8-0.71.6
Compulsive drug intake0.10.10.30.50.30.00.6-0.2-0.4-0.20.1-0.20.30.10.4
One hour access (shock baseline)0.10.10.2-0.4-0.20.4-0.0-0.10.20.00.1-0.1-0.4-0.20.3
Social response proportion0.20.21.0-0.2-0.4-1.00.20.2-0.50.20.50.70.30.40.3
Social responses0.40.51.8-0.4-0.7-1.10.10.3-0.6-0.40.81.30.60.50.2
Social time2.53.36.7-2.42.20.52.6-2.61.50.9-0.4-1.8-1.9-2.00.9
Soleus weight0.20.51.5-0.5-0.71.0-0.90.50.1-1.2-0.80.50.20.2-0.8
Bone: stiffness0.10.10.2-0.2-0.30.1-0.30.20.10.4-0.40.10.20.3-0.4
Tibialis anterior weight0.20.92.4-1.20.51.6-0.3-0.51.20.4-1.1-1.0-0.9-0.8-0.6
Time to tail flick, vehicle, before self-admin0.10.10.8-0.50.0-0.5-0.1-0.10.10.9-0.10.10.00.1-0.1
Time to tail flick, vehicle, after self-admin1.11.22.71.0-0.9-1.6-0.50.7-1.3-0.91.51.21.21.10.8
Time to tail flick, test, before self-admin3.13.19.70.41.8-0.82.8-2.2-0.8-0.12.4-1.5-1.1-0.63.1
Time to tail flick, test, after self-admin0.20.21.90.1-0.20.60.1-0.2-0.1-1.4-0.2-0.10.10.20.1
Delta time to tail flick, vehicle, before/after SA0.40.41.30.6-0.3-0.80.30.0-0.8-0.91.10.40.40.50.9
Delta time to tail flick, test, before/after SA2.42.26.7-0.4-1.31.5-2.21.40.9-1.2-2.31.00.50.2-2.6
Tibia length0.72.03.7-1.61.61.51.4-1.81.30.7-0.5-1.9-1.5-1.50.7
Ambulatory time before self-admin1.01.13.2-0.90.41.4-0.5-0.31.30.4-1.8-0.6-1.1-1.0-1.4
Ambulatory time after self-admin0.40.42.6-0.3-0.21.6-0.90.10.6-0.1-0.9-0.6-0.3-0.3-0.5
Bone: tissue strength0.60.61.5-1.20.80.50.3-0.51.10.3-0.8-0.4-0.8-1.0-0.6
Total heroin consumption0.10.10.8-0.90.1-0.30.4-0.10.30.40.00.30.00.10.0
Bone: trabecular number0.71.03.60.5-0.3-1.70.30.2-1.21.90.90.31.11.00.9
Bone: trabecular spacing1.62.04.0-1.81.51.30.8-1.32.0-0.6-1.0-1.3-2.0-1.9-0.6
Bone: trabecular thickness2.63.16.32.0-1.0-2.30.20.8-2.50.82.21.02.32.11.8
Bone: trabecular tissue density3.44.810.1-1.73.01.32.7-3.01.61.6-0.2-3.2-2.2-2.31.5
Water consumed over 24 hours1.92.36.6-2.01.30.60.8-1.21.72.6-1.7-1.3-1.6-1.5-0.6
Number of responses in last shaping day0.60.62.8-0.40.51.70.0-0.50.7-0.3-0.6-1.0-0.9-0.8-0.1