Hub : Genes

Snrpd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	mRNA stability	Snrpd2	0.15	0.12	2.7e-08	0.06	0.07	0.07	0.07	1.6e-07	7.7e-08	1.6e-08	4.1e-08
2	Adipose	isoform ratio	NM_001109399.2	0.02	0.02	9.6e-03	0.01	0.01	0.01	0	3.5e-02	4.2e-02	3.9e-02	8.3e-02
3	Adipose	alternative TSS	NM_001109399.2	0.02	0.02	4.3e-03	0.01	0.01	0.01	0.01	2.0e-02	2.3e-02	3.1e-02	5.5e-02
4	Adipose	alternative TSS	XM_063273625.1	0.02	0.02	5.8e-03	0.01	0.01	0.01	0	2.9e-02	3.5e-02	4.6e-02	9.0e-02
5	Adipose	gene expression	Snrpd2	0.27	0.16	0.0e+00	0.19	0.19	0.19	0.19	2.5e-20	2.5e-20	1.7e-20	4.6e-21
6	Brain	gene expression	Snrpd2	0.09	0.08	5.9e-08	0.07	0.07	0.07	0.07	7.5e-07	2.6e-07	1.9e-07	7.9e-07
7	PL	gene expression	Snrpd2	0.04	0.03	1.9e-04	0.03	0.04	0.03	0.03	4.6e-04	9.9e-05	2.3e-04	3.4e-04
8	pVTA	gene expression	Snrpd2	0.05	0.06	9.7e-03	0.01	0.01	0	0.01	6.2e-02	3.8e-02	1.7e-01	9.2e-02
9	LHb	gene expression	Snrpd2	0.14	0.14	6.2e-03	0.1	0.08	0.09	0.08	2.5e-03	5.4e-03	4.8e-03	6.6e-03
10	NAcc	gene expression	Snrpd2	0.05	0.04	1.5e-07	0.04	0.04	0.04	0.04	2.8e-07	3.5e-07	1.2e-06	1.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.0	0.0	0.0	-0.0	-0.2	-0.2	0.2	-0.0	-0.0	-0.0	-0.0	-0.1	-0.1
Area under the delay curve	1.2	1.8	2.7	1.0	1.0	1.3	-1.3	-1.2	1.4	-1.4	-1.4	1.6	1.6
BMI with tail	0.7	2.6	4.0	-1.7	-2.0	-1.7	1.7	1.7	-1.5	1.4	1.3	-1.5	-1.5
BMI without tail	0.6	3.0	5.6	-2.0	-2.4	-1.9	1.9	2.0	-1.6	1.5	1.3	-1.3	-1.3
Body weight	1.5	6.6	10.2	-2.8	-3.2	-2.7	2.7	2.8	-2.5	2.3	2.1	-2.2	-2.2
Weight adjusted by age	0.0	0.0	0.1	0.0	-0.1	-0.4	0.4	0.0	0.0	0.0	0.0	0.0	0.0
Bone surface	0.3	0.6	0.8	-0.8	-0.9	-0.8	0.8	0.8	-0.6	0.6	0.6	-0.8	-0.8
Bone volume	0.2	0.4	0.5	-0.6	-0.7	-0.7	0.7	0.6	-0.5	0.5	0.5	-0.7	-0.7
Breakpoint value in progressive ratio session	1.6	2.9	3.5	1.9	1.8	1.7	-1.7	-1.7	1.5	-1.6	-1.6	1.7	1.7
Number of licking bursts	1.2	3.7	4.7	-2.2	-1.9	-2.0	2.0	2.0	-2.1	2.0	2.0	-1.5	-1.5
Context. condit. distance diff. score	0.1	0.1	0.2	-0.1	-0.1	-0.1	0.1	0.2	-0.3	0.4	0.4	-0.4	-0.4
Locomotion velocity, session 1	0.1	0.1	0.3	0.6	0.5	0.2	-0.2	-0.4	0.2	-0.2	-0.2	0.4	0.4
Locomotion distance, session 1	0.0	0.0	0.2	0.2	0.2	-0.0	0.0	-0.1	0.1	0.1	0.2	-0.4	-0.4
Locomotion velocity, session 2	1.4	1.7	2.3	-1.5	-1.5	-1.3	1.3	1.4	-1.3	1.3	1.2	-1.0	-1.0
Locomotion distance, session 2	0.3	0.4	0.8	-0.5	-0.6	-0.6	0.6	0.6	-0.4	0.6	0.6	-0.9	-0.9
Locomotion velocity, session 3	0.3	0.3	0.5	-0.7	-0.7	-0.5	0.5	0.6	-0.5	0.5	0.5	-0.5	-0.5
Locomotion distance, session 3	0.7	0.8	1.1	0.7	0.7	1.0	-1.0	-0.8	1.1	-0.9	-0.9	0.8	0.8
Stereotopy head waving bouts, day 3	0.9	1.1	1.4	-1.2	-1.0	-1.1	1.1	1.1	-1.2	1.1	1.1	-0.7	-0.7
Stereotopy head waving duration, day 3	0.9	1.1	1.4	-1.0	-0.9	-1.0	1.0	1.0	-1.1	1.1	1.2	-1.0	-1.0
Locomotion velocity, session 7	0.2	0.2	0.4	0.7	0.5	0.6	-0.6	-0.5	0.5	-0.4	-0.4	0.1	0.1
Locomotion distance, session 7	0.0	0.0	0.1	-0.2	-0.3	-0.0	0.0	0.2	-0.0	0.1	0.1	-0.3	-0.3
Stereotopy head waving bouts, day 7	0.9	1.0	1.4	-0.9	-0.8	-1.1	1.1	0.9	-1.2	1.1	1.1	-1.0	-1.0
Stereotopy head waving duration, day 7	0.7	0.9	1.2	-1.0	-0.8	-1.1	1.1	0.9	-1.1	1.0	1.0	-0.8	-0.8
Locomotion velocity, session 8	0.0	0.0	0.0	0.1	0.1	0.2	-0.2	-0.1	0.1	-0.1	-0.0	0.1	0.1
Locomotion distance, session 8	0.0	0.0	0.2	0.1	-0.0	0.1	-0.1	0.0	0.1	0.1	0.1	-0.4	-0.4
Degree of sensitization distance	0.5	0.6	0.6	-0.7	-0.7	-0.7	0.7	0.8	-0.8	0.8	0.8	-0.8	-0.8
Degree of sensitization stereotypy	1.0	1.1	1.5	-0.9	-0.9	-1.2	1.2	0.9	-1.2	1.1	1.1	-1.0	-1.0
Conditioned locomotion	0.0	0.0	0.1	0.3	0.3	0.2	-0.2	-0.3	0.2	-0.2	-0.2	0.1	0.1
Cocaine response after cond. corrected	0.4	0.6	1.1	-0.7	-0.6	-0.6	0.6	0.7	-0.8	0.8	0.8	-1.0	-1.0
Cocaine response after cond. not corrected	1.2	1.7	2.4	-1.2	-1.2	-1.1	1.1	1.2	-1.3	1.3	1.3	-1.5	-1.5
Cocaine response before conditioning	1.7	2.0	2.3	-1.4	-1.5	-1.5	1.5	1.4	-1.5	1.4	1.4	-1.3	-1.3
Saline control response	2.0	2.8	3.1	-1.8	-1.6	-1.7	1.7	1.7	-1.7	1.7	1.7	-1.6	-1.6
Bone: connectivity density	0.0	0.0	0.1	0.1	-0.1	-0.1	0.1	-0.1	0.2	-0.2	-0.2	-0.1	-0.1
Bone: cortical apparent density	0.0	0.1	0.2	0.5	0.2	0.1	-0.1	-0.3	0.2	-0.3	-0.3	0.1	0.1
Bone: cortical area	1.5	2.4	3.4	-1.8	-1.6	-1.4	1.4	1.6	-1.6	1.6	1.6	-1.4	-1.4
Bone: cortical porosity	0.2	0.2	0.4	0.2	0.4	0.6	-0.6	-0.3	0.4	-0.4	-0.4	0.6	0.6
Bone: cortical porosity	0.0	0.0	0.1	-0.3	-0.1	0.2	-0.2	0.1	-0.1	-0.0	-0.0	0.2	0.2
Bone: cortical thickness	0.6	0.9	1.2	-1.1	-0.9	-0.9	0.9	1.0	-1.0	1.0	1.0	-1.0	-1.0
Bone: cortical thickness	1.3	1.6	1.8	-1.3	-1.2	-1.3	1.3	1.2	-1.3	1.3	1.3	-1.3	-1.3
Bone: cortical tissue density	0.1	0.1	0.3	0.6	0.3	0.2	-0.2	-0.4	0.3	-0.4	-0.4	0.2	0.2
Condit. Reinf. active minus inactive responses	0.5	0.6	0.8	-0.8	-0.9	-0.8	0.8	0.7	-0.8	0.7	0.6	-0.8	-0.8
Condit. Reinf. active-inactive response ratio	0.4	0.5	0.6	-0.6	-0.8	-0.7	0.7	0.6	-0.7	0.6	0.5	-0.8	-0.8
Condit. Reinf. active responses	0.3	0.4	0.7	-0.6	-0.7	-0.6	0.6	0.6	-0.6	0.5	0.5	-0.8	-0.8
Condit. Reinf. inactive responses	0.1	0.1	0.2	0.4	0.4	0.4	-0.4	-0.3	0.4	-0.2	-0.2	-0.2	-0.2
Incentive salience index mean	0.4	0.5	0.8	-0.8	-0.9	-0.8	0.8	0.7	-0.7	0.5	0.5	-0.6	-0.6
Condit. Reinf. lever presses	0.1	0.1	0.4	-0.4	-0.6	-0.4	0.4	0.4	-0.3	0.1	0.1	-0.2	-0.2
Condit. Reinf. active minus inactive responses	0.0	0.1	0.2	-0.1	-0.0	-0.1	0.1	0.1	-0.2	0.3	0.3	-0.4	-0.4
Condit. Reinf. active-inactive response ratio	0.2	0.3	0.8	-0.3	-0.2	-0.4	0.4	0.4	-0.5	0.6	0.7	-0.9	-0.9
Condit. Reinf. active responses	0.1	0.1	0.2	0.4	0.4	0.4	-0.4	-0.4	0.3	-0.3	-0.3	0.3	0.3
Condit. Reinf. inactive responses	0.6	0.9	1.1	0.9	0.9	0.9	-0.9	-0.9	0.8	-0.9	-0.9	1.0	1.0
Condit. Reinf. lever presses	0.1	0.1	0.2	-0.4	-0.4	-0.2	0.2	0.4	-0.3	0.4	0.4	-0.4	-0.4
Condit. Reinf. lever reinforcers received	0.1	0.2	0.2	0.4	0.5	0.5	-0.5	-0.4	0.4	-0.4	-0.3	0.4	0.4
Conditioned reinforcement - actives	0.7	2.7	3.6	-1.8	-1.9	-1.9	1.9	1.7	-1.4	1.5	1.4	-1.5	-1.5
Conditioned reinforcement - inactives	0.4	1.1	2.4	-1.2	-1.6	-1.2	1.2	1.2	-0.7	0.8	0.7	-0.7	-0.7
Conditioned locomotion	1.9	2.9	4.1	-1.4	-1.4	-2.0	2.0	1.5	-1.7	1.7	1.8	-1.7	-1.7
Patch foraging indifference point 0 sec	0.2	0.5	0.9	-0.7	-0.4	-0.3	0.3	0.6	-0.7	0.9	0.9	-0.8	-0.8
Patch foraging indifference point AUC	2.3	5.4	7.2	-2.4	-2.6	-2.7	2.7	2.4	-2.3	2.1	2.0	-1.9	-1.9
Delay disc. indifference point, 0s delay	1.0	1.1	1.7	0.9	0.7	0.9	-0.9	-0.9	1.1	-1.2	-1.2	1.3	1.3
Delay disc. indifference point, 16s delay	0.7	1.1	1.6	0.7	0.6	1.0	-1.0	-0.9	1.1	-1.1	-1.1	1.2	1.2
Delay disc. indifference point, 2s delay	3.1	3.5	5.7	1.5	1.3	1.5	-1.5	-1.6	1.9	-2.0	-2.0	2.4	2.4
Delay disc. indifference point, 24s delay	0.0	0.0	0.1	-0.2	0.0	0.2	-0.2	0.0	-0.1	0.2	0.3	-0.3	-0.3
Delay disc. indifference point, 4s delay	0.0	0.0	0.0	-0.0	-0.1	-0.1	0.1	0.0	-0.0	-0.0	-0.0	0.2	0.2
Delay disc. indifference point, 8s delay	1.1	1.9	2.4	1.3	1.3	1.3	-1.3	-1.3	1.3	-1.4	-1.4	1.6	1.6
Indifference point function ln k	0.8	2.5	4.4	1.6	1.9	2.1	-2.1	-1.7	1.5	-1.2	-1.1	1.0	1.0
Indifference point function log k	0.8	2.5	4.4	1.6	1.9	2.1	-2.1	-1.7	1.5	-1.2	-1.1	1.0	1.0
Patch foraging total patch changes 0 sec	0.3	0.8	1.3	-0.8	-0.6	-0.5	0.5	0.8	-0.9	1.1	1.2	-1.1	-1.1
Patch foraging total patch changes 12 sec	1.8	2.4	3.3	-1.8	-1.8	-1.7	1.7	1.7	-1.6	1.4	1.3	-1.2	-1.2
Patch foraging total patch changes 18 sec	1.3	3.1	3.6	-1.5	-1.5	-1.9	1.9	1.6	-1.9	1.7	1.8	-1.8	-1.8
Patch foraging total patch changes 24 sec	0.3	1.0	2.1	-0.9	-1.1	-1.4	1.4	1.0	-0.9	0.8	0.7	-0.8	-0.8
Patch foraging total patch changes 6 sec	2.1	3.5	3.9	-2.0	-1.8	-1.6	1.6	1.9	-2.0	1.9	2.0	-1.9	-1.9
Patch foraging time to switch 0 sec	1.3	4.9	6.6	2.3	2.1	1.9	-1.9	-2.2	2.1	-2.3	-2.3	2.6	2.6
Patch foraging water rate 0 sec	1.5	5.7	6.7	-2.5	-2.3	-2.1	2.1	2.4	-2.3	2.5	2.5	-2.6	-2.6
Patch foraging water rate 12 sec	0.1	0.2	0.5	-0.5	-0.4	-0.3	0.3	0.4	-0.3	0.5	0.5	-0.7	-0.7
Patch foraging water rate 18 sec	0.1	0.2	0.3	-0.5	-0.5	-0.3	0.3	0.5	-0.1	0.4	0.4	-0.6	-0.6
Patch foraging water rate 24 sec	0.4	0.6	1.0	-0.6	-0.4	-0.5	0.5	0.6	-0.8	0.9	0.9	-1.0	-1.0
Patch foraging water rate 6 sec	0.7	1.0	1.5	-1.0	-1.0	-1.0	1.0	1.0	-0.8	1.0	1.0	-1.2	-1.2
Seeking ratio, delayed vs. immediate footshock	1.7	2.4	3.1	1.8	1.7	1.5	-1.5	-1.6	1.5	-1.5	-1.5	1.4	1.4
Distance traveled before self-admin	0.0	0.0	0.1	-0.1	-0.1	-0.1	0.1	0.2	-0.0	0.3	0.3	-0.3	-0.3
Distance traveled after self-admin	0.2	0.3	0.6	0.5	0.8	0.6	-0.6	-0.6	0.7	-0.5	-0.4	0.4	0.4
Extensor digitorum longus weight	2.0	8.0	9.4	-3.1	-3.0	-3.1	3.1	2.9	-2.8	2.7	2.7	-2.4	-2.4
Bone: elastic displacement	0.7	0.9	1.1	1.0	0.9	0.8	-0.8	-1.0	0.8	-1.0	-1.0	1.0	1.0
Bone: elastic work	0.1	0.1	0.2	-0.4	-0.4	-0.3	0.3	0.3	-0.3	0.2	0.1	-0.1	-0.1
Bone: endosteal estimation	0.0	0.0	0.1	-0.0	-0.2	0.2	-0.2	0.0	0.2	-0.2	-0.3	0.2	0.2
Bone: endosteal perimeter	0.0	0.0	0.0	-0.1	-0.1	0.2	-0.2	0.1	0.0	-0.0	-0.0	0.1	0.1
Epididymis fat weight	0.1	0.6	0.9	0.7	0.5	0.6	-0.6	-0.7	0.8	-0.9	-0.9	1.0	1.0
Delta time in closed arm before/after self-admin	0.5	0.4	0.9	0.8	0.9	0.9	-0.9	-0.7	0.5	-0.3	-0.2	0.2	0.2
Delta time in open arm before/after self-admin	0.1	0.1	0.4	-0.4	-0.5	-0.6	0.6	0.3	-0.0	-0.1	-0.2	0.2	0.2
Diff in mean of infusions in LGA sessions	1.0	1.8	2.7	1.5	1.6	1.1	-1.1	-1.5	1.1	-1.3	-1.3	1.3	1.3
Delay discount exponential model param	1.0	1.3	2.0	-0.9	-0.8	-1.1	1.1	1.0	-1.2	1.2	1.2	-1.4	-1.4
Extinction: sum of active levers before priming	0.0	0.1	0.1	0.2	0.2	0.3	-0.3	-0.1	-0.2	-0.2	-0.2	0.3	0.3
Active lever presses in extinction session 6	0.1	0.1	0.3	-0.6	-0.6	-0.3	0.3	0.5	-0.4	0.3	0.2	-0.2	-0.2
Bone: final force	0.4	0.7	1.0	-1.0	-1.0	-0.8	0.8	0.9	-0.9	0.8	0.8	-0.6	-0.6
Bone: final moment	0.6	1.0	1.6	-1.2	-1.2	-0.9	0.9	1.1	-1.1	1.0	0.9	-0.7	-0.7
Food consumed during 24 hour testing period	3.4	6.9	8.0	2.8	2.7	2.6	-2.6	-2.7	2.7	-2.7	-2.6	2.4	2.4
Glucose	0.4	0.6	1.0	1.0	1.0	0.8	-0.8	-0.8	0.7	-0.6	-0.6	0.8	0.8
Heart weight	1.9	3.0	3.5	-1.8	-1.6	-1.7	1.7	1.8	-1.8	1.8	1.9	-1.7	-1.7
Delay discount hyperbolic model param	0.9	1.2	1.9	-0.8	-0.8	-1.0	1.0	1.0	-1.1	1.1	1.1	-1.4	-1.4
Intermittent access intake day 1-15 change	0.0	0.2	0.3	-0.6	-0.5	-0.4	0.4	0.4	-0.4	0.4	0.4	-0.4	-0.4
Intermittent access intake escalation	0.1	0.3	0.5	-0.7	-0.7	-0.5	0.5	0.6	-0.5	0.5	0.5	-0.5	-0.5
Intermittent access intake escalation 2	0.0	0.0	0.2	0.1	0.3	0.4	-0.4	-0.2	0.0	0.0	0.1	-0.1	-0.1
Intermitt. access day 1 inactive lever presses	0.0	0.1	0.2	-0.2	-0.5	-0.3	0.3	0.3	-0.1	0.1	0.0	-0.0	-0.0
Intermitt. access day 15 inactive lever presses	0.0	0.1	0.3	0.2	-0.2	-0.6	0.6	0.2	0.1	0.1	0.0	-0.0	-0.0
Intermitt. access escalation Index	0.1	0.3	0.4	0.6	0.6	0.5	-0.5	-0.6	0.4	-0.5	-0.5	0.5	0.5
Intermittent access day 1 total infusions	1.1	3.2	4.5	-2.0	-2.1	-2.0	2.0	1.9	-1.5	1.6	1.5	-1.5	-1.5
Intermittent access day 15 total infusions	0.7	1.7	2.8	-1.2	-1.4	-1.7	1.7	1.3	-1.1	1.1	1.0	-1.0	-1.0
Intermittent access terminal intake (last 3 days)	1.0	1.8	2.5	-1.3	-1.4	-1.6	1.6	1.3	-1.3	1.2	1.2	-1.2	-1.2
Intermittent access total infusions	3.0	3.5	4.8	-1.8	-1.9	-2.2	2.2	1.9	-1.9	1.7	1.7	-1.7	-1.7
Intermittent access day 1 locomotion	0.3	0.6	1.1	-0.7	-1.0	-1.1	1.1	0.8	-0.6	0.6	0.6	-0.6	-0.6
Intermittent access day 15 total locomotion	0.1	0.3	0.5	-0.5	-0.6	-0.7	0.7	0.6	-0.3	0.5	0.5	-0.5	-0.5
Intermittent access total locomotion	1.9	2.3	3.0	-1.5	-1.6	-1.7	1.7	1.5	-1.3	1.4	1.4	-1.4	-1.4
Intermittent access standard deviation	0.0	0.2	0.3	0.5	0.5	0.4	-0.4	-0.5	0.4	-0.5	-0.4	0.5	0.5
Left kidney weight	3.5	27.8	31.0	-5.6	-5.6	-5.1	5.1	5.4	-5.2	5.1	5.0	-5.4	-5.4
Right kidney weight	3.5	24.7	26.5	-5.1	-5.2	-4.8	4.8	5.0	-5.1	4.8	4.8	-5.1	-5.1
Cocaine induced anxiety	0.1	0.2	0.3	0.6	0.0	-0.3	0.3	-0.2	0.4	-0.5	-0.5	0.6	0.6
Post-drug Anxiety	0.0	0.0	0.1	0.3	0.1	-0.1	0.1	-0.1	0.1	-0.2	-0.2	0.3	0.3
Baseline Anxiety	0.2	0.3	1.0	0.5	1.0	0.8	-0.8	-0.6	-0.0	-0.0	0.1	-0.0	-0.0
Tail length	0.4	1.9	3.7	-1.7	-1.9	-1.4	1.4	1.6	-1.3	1.2	1.1	-0.9	-0.9
Length with tail	0.5	2.0	3.5	-1.7	-1.9	-1.5	1.5	1.6	-1.4	1.2	1.2	-1.1	-1.1
Length without tail	0.3	1.3	1.6	-1.1	-1.2	-1.3	1.3	1.1	-1.2	1.0	1.0	-1.1	-1.1
Times rat made contact with spout	0.1	0.1	0.2	0.4	0.4	0.4	-0.4	-0.3	0.2	-0.1	-0.1	-0.2	-0.2
Lifetime Intake	3.0	3.7	5.2	-1.9	-2.1	-2.3	2.3	1.9	-1.9	1.7	1.7	-1.7	-1.7
Liver weight, left	2.2	3.8	4.6	-2.2	-2.1	-2.0	2.0	2.0	-2.0	1.9	1.9	-1.7	-1.7
Liver weight, right	1.8	3.1	4.4	-1.9	-2.1	-1.8	1.8	1.8	-1.8	1.5	1.5	-1.6	-1.6
Locomotor activity	1.9	3.0	3.6	-1.9	-1.6	-1.6	1.6	1.8	-1.8	1.9	1.9	-1.6	-1.6
Locomotor testing distance	0.8	2.0	2.5	-1.6	-1.4	-1.5	1.5	1.5	-1.2	1.4	1.4	-1.3	-1.3
Locomotor testing rearing	2.5	9.1	9.9	-3.1	-3.1	-3.1	3.1	3.1	-3.0	3.0	2.9	-2.9	-2.9
Locomotion in novel chamber	0.4	0.6	1.5	0.6	1.0	1.2	-1.2	-0.8	0.5	-0.5	-0.4	0.4	0.4
Locomotion in novel chamber post-restriction	0.6	1.7	2.6	1.2	1.3	1.6	-1.6	-1.2	1.4	-1.2	-1.2	1.1	1.1
Fecal boli incidents, locomotor time 1	0.0	0.1	0.3	-0.5	-0.4	-0.1	0.1	0.4	-0.2	0.2	0.2	-0.1	-0.1
Change in fecal boli incidents, locomotor task	0.7	0.7	1.1	0.8	0.6	0.7	-0.7	-0.7	0.8	-0.9	-0.9	1.1	1.1
Time >=10cm from walls, locomotor time 1	0.0	0.0	0.1	0.1	0.0	0.0	-0.0	-0.0	0.1	-0.0	-0.0	-0.3	-0.3
Bouts of movement, locomotor time 1	2.1	2.7	3.6	1.9	1.6	1.7	-1.7	-1.7	1.7	-1.6	-1.6	1.5	1.5
Total resting periods, locomotor time 1	2.9	3.4	4.4	2.1	1.8	1.8	-1.8	-1.9	1.9	-1.9	-1.8	1.7	1.7
Rest time, locomotor task time 1	0.1	0.2	0.3	0.6	0.4	0.5	-0.5	-0.4	0.5	-0.5	-0.5	0.3	0.3
Distance moved, locomotor task time 1	0.2	0.5	0.7	-0.8	-0.7	-0.8	0.8	0.7	-0.8	0.7	0.7	-0.5	-0.5
Vertical activity count, locomotor time 1	0.0	0.1	0.1	-0.4	-0.4	-0.3	0.3	0.2	-0.2	-0.0	-0.1	0.3	0.3
Time >=10cm from walls, locomotor time 2	0.0	0.1	0.2	0.2	0.1	0.3	-0.3	-0.2	0.3	-0.3	-0.3	0.4	0.4
Bouts of movement, locomotor time 2	2.4	8.0	10.5	3.2	3.1	2.8	-2.8	-3.0	2.8	-2.7	-2.6	2.5	2.5
Total resting periods, locomotor time 2	1.8	7.3	10.0	3.2	3.1	2.7	-2.7	-2.9	2.7	-2.6	-2.5	2.3	2.3
Rest time, locomotor task time 2	0.1	0.1	0.4	0.7	0.5	0.3	-0.3	-0.4	0.2	-0.2	-0.1	-0.1	-0.1
Distance moved, locomotor task time 2	0.7	0.9	1.6	-1.3	-1.2	-0.9	0.9	1.1	-1.0	1.0	0.9	-0.6	-0.6
Vertical activity count, locomotor time 2	0.1	0.1	0.4	-0.3	-0.4	0.0	-0.0	0.1	0.1	-0.3	-0.4	0.6	0.6
Light reinforcement 1	0.0	0.2	0.2	-0.4	-0.5	-0.5	0.5	0.4	-0.2	0.4	0.4	-0.5	-0.5
Light reinforcement 2	0.2	0.4	1.0	-0.8	-1.0	-0.8	0.8	0.8	-0.4	0.3	0.2	-0.3	-0.3
Bone: marrow area	0.0	0.0	0.1	-0.1	-0.3	0.2	-0.2	0.1	0.1	-0.2	-0.2	0.2	0.2
Bone: maximum diameter	2.1	4.3	5.3	-2.3	-2.2	-1.9	1.9	2.2	-2.1	2.1	2.0	-2.0	-2.0
Bone: maximum force	0.2	0.3	0.6	-0.8	-0.7	-0.5	0.5	0.6	-0.6	0.5	0.5	-0.4	-0.4
Bone: maximum moment	0.2	0.4	0.9	-0.9	-0.9	-0.5	0.5	0.8	-0.7	0.6	0.6	-0.4	-0.4
Mean time between licks in bursts	0.0	0.1	0.1	0.1	0.1	0.2	-0.2	-0.2	0.2	-0.3	-0.3	0.4	0.4
Mean num. licks in bursts	1.6	4.3	6.0	2.4	2.2	2.3	-2.3	-2.2	2.3	-2.0	-2.0	1.3	1.3
Cd content in liver	0.1	0.2	0.6	0.8	0.7	0.2	-0.2	-0.5	0.3	-0.2	-0.2	0.0	0.0
Co content in liver	1.2	1.4	1.8	1.3	1.2	1.0	-1.0	-1.2	1.1	-1.2	-1.2	1.3	1.3
Cu content in liver	0.4	0.5	0.8	-0.8	-0.8	-0.9	0.9	0.7	-0.7	0.6	0.6	-0.4	-0.4
Fe content in liver	4.4	5.4	6.7	-2.3	-2.0	-2.5	2.5	2.3	-2.6	2.5	2.5	-2.0	-2.0
K content in liver	0.3	0.3	1.1	-1.1	-0.8	-0.5	0.5	0.7	-0.4	0.4	0.3	0.0	0.0
Mg content in liver	0.6	0.7	1.4	-1.2	-1.1	-0.8	0.8	1.0	-0.8	0.8	0.7	-0.4	-0.4
Mn content in liver	1.1	1.2	1.9	-1.4	-1.3	-1.1	1.1	1.2	-1.1	1.0	1.0	-1.0	-1.0
Na content in liver	0.1	0.1	0.3	-0.5	-0.2	-0.4	0.4	0.4	-0.4	0.4	0.5	-0.0	-0.0
Rb content in liver	0.1	0.1	0.3	-0.2	-0.2	-0.1	0.1	0.2	-0.2	0.3	0.3	-0.5	-0.5
Se content in liver	3.9	4.6	5.9	-2.4	-2.3	-2.2	2.2	2.3	-2.3	2.2	2.1	-1.7	-1.7
Sr content in liver	0.0	0.0	0.1	-0.2	-0.2	-0.2	0.2	0.2	-0.2	0.2	0.2	0.2	0.2
Zn content in liver	1.0	1.1	2.0	-1.4	-1.3	-1.1	1.1	1.2	-1.0	0.9	0.9	-0.7	-0.7
Bone: minimum diameter	0.2	0.4	0.7	-0.9	-0.8	-0.5	0.5	0.7	-0.5	0.6	0.6	-0.4	-0.4
Time in familiar zone, hab. session 1	0.1	0.1	0.2	-0.4	-0.2	-0.2	0.2	0.3	-0.3	0.4	0.4	-0.3	-0.3
Time in novel zone, hab. session 1	0.7	0.7	1.0	-0.9	-0.9	-1.0	1.0	0.8	-1.0	0.8	0.8	-0.7	-0.7
Total zone transitions, hab. session 1	0.1	0.2	0.5	-0.2	-0.2	-0.4	0.4	0.3	-0.3	0.4	0.5	-0.7	-0.7
Total locomotion distance, hab. session 1	0.4	0.5	0.7	0.7	0.7	0.7	-0.7	-0.7	0.8	-0.7	-0.7	0.8	0.8
Locomotion velocity, hab. session 1	1.2	1.7	2.0	1.3	1.2	1.2	-1.2	-1.3	1.4	-1.3	-1.3	1.3	1.3
Time in familiar zone, hab. session 2	0.3	0.3	0.5	-0.5	-0.6	-0.7	0.7	0.6	-0.7	0.6	0.5	-0.3	-0.3
Time in novel zone, hab. session 2	0.1	0.2	0.3	0.4	0.6	0.6	-0.6	-0.4	0.4	-0.2	-0.2	0.1	0.1
Total zone transitions, hab. session 2	0.4	0.6	0.7	-0.8	-0.7	-0.8	0.8	0.7	-0.8	0.8	0.8	-0.6	-0.6
Total locomotion distance, hab. session 2	0.5	0.7	1.0	0.7	0.8	0.7	-0.7	-0.8	0.8	-0.8	-0.8	1.0	1.0
Locomotion velocity, hab. session 2	0.3	0.4	0.6	0.5	0.6	0.6	-0.6	-0.6	0.7	-0.7	-0.7	0.8	0.8
Novel to familiar place preference ratio	0.5	0.7	1.8	-0.6	-0.7	-0.6	0.6	0.7	-0.5	0.8	0.8	-1.3	-1.3
Novelty place preference	0.5	0.6	1.6	-0.6	-0.6	-0.5	0.5	0.6	-0.4	0.7	0.8	-1.2	-1.2
Time in novel zone, NPP test	0.6	0.7	1.7	-0.7	-0.6	-0.5	0.5	0.7	-0.5	0.8	0.9	-1.3	-1.3
Total zone transitions, NPP test	0.1	0.1	0.2	-0.4	-0.3	-0.2	0.2	0.4	-0.2	0.4	0.4	-0.4	-0.4
Total locomotion distance, NPP test	0.1	0.1	0.2	-0.2	-0.1	-0.1	0.1	0.2	-0.2	0.3	0.4	-0.4	-0.4
Locomotion velocity, NPP test	0.0	0.1	0.2	-0.2	-0.1	-0.1	0.1	0.2	-0.1	0.3	0.3	-0.4	-0.4
Intraocular pressure	0.1	0.1	0.5	0.4	0.7	0.5	-0.5	-0.4	0.0	-0.1	-0.0	0.2	0.2
Delta distance traveled before/after self-admin	1.3	1.4	2.2	0.9	0.8	1.0	-1.0	-1.0	1.3	-1.4	-1.5	1.4	1.4
Delta ambulatory time before/after self-admin	0.2	0.3	0.6	0.4	0.3	0.4	-0.4	-0.5	0.8	-0.7	-0.7	0.7	0.7
Parametrial fat weight	0.1	0.2	0.4	-0.5	-0.6	-0.4	0.4	0.5	-0.5	0.4	0.3	-0.5	-0.5
Pavlov. Cond. lever latency	0.6	0.8	1.0	0.8	0.9	1.0	-1.0	-0.8	0.9	-0.8	-0.8	0.8	0.8
Pavlov. Cond. magazine entry latency	0.1	0.1	0.2	-0.4	-0.4	-0.4	0.4	0.3	-0.4	0.3	0.3	-0.3	-0.3
Pavlov. Cond. change in total contacts	0.5	0.5	0.8	0.9	0.7	0.6	-0.6	-0.8	0.7	-0.8	-0.8	0.6	0.6
Pavlov. Cond. index score	0.3	0.4	0.5	-0.6	-0.6	-0.7	0.7	0.6	-0.7	0.6	0.5	-0.6	-0.6
Pavlov. Cond. latency score	0.1	0.1	0.2	-0.3	-0.3	-0.5	0.5	0.3	-0.4	0.3	0.2	-0.2	-0.2
Pavlov. Cond. lever contacts	0.4	0.5	0.7	-0.7	-0.7	-0.8	0.8	0.7	-0.7	0.6	0.6	-0.6	-0.6
Pavlov. Cond. magazine entry number	0.0	0.0	0.1	0.3	0.2	0.3	-0.3	-0.1	0.3	-0.1	-0.1	0.1	0.1
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	-0.1	-0.1	-0.3	0.3	0.2	-0.3	0.3	0.3	-0.5	-0.5
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.4	0.5	-0.6	-0.6	-0.7	0.7	0.6	-0.7	0.6	0.6	-0.6	-0.6
Pavlov. Cond. response bias	1.0	1.2	1.4	-1.2	-1.2	-1.1	1.1	1.0	-1.1	1.0	1.0	-1.1	-1.1
Pavlov. Cond. lever latency	0.0	0.0	0.0	0.2	0.2	0.1	-0.1	-0.2	0.1	-0.1	-0.1	0.0	0.0
Pavlov. Cond. magazine entry latency	0.0	0.1	0.3	0.1	-0.1	-0.1	0.1	0.1	-0.1	0.1	0.1	-0.5	-0.5
Pavlov. Cond. change in total contacts	0.2	0.4	0.6	0.6	0.7	0.7	-0.7	-0.7	0.7	-0.5	-0.5	0.4	0.4
Pavlov. Cond. index score	0.0	0.0	0.1	0.2	0.1	0.2	-0.2	-0.2	0.2	-0.2	-0.2	-0.1	-0.1
Pavlov. Cond. latency score	0.0	0.1	0.1	0.3	0.2	0.3	-0.3	-0.3	0.3	-0.3	-0.3	0.1	0.1
Pavlov. Cond. lever contacts	0.1	0.1	0.2	-0.4	-0.4	-0.2	0.2	0.4	-0.3	0.3	0.3	-0.3	-0.3
Pavlov. Cond. magazine entry number	0.3	0.4	0.6	-0.8	-0.6	-0.6	0.6	0.6	-0.7	0.6	0.6	-0.3	-0.3
Pavlov. Cond. intertrial magazine entries	0.0	0.0	0.0	-0.0	0.1	-0.0	0.0	-0.0	-0.0	0.1	0.1	-0.1	-0.1
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.0	0.0	0.0	-0.0	0.0	-0.0	0.0	0.0	0.0	0.0	-0.2	-0.2
Pavlov. Cond. response bias	0.0	0.0	0.0	0.1	0.0	0.1	-0.1	-0.0	0.1	-0.1	-0.1	-0.1	-0.1
Time in closed arm before self-admin	0.6	1.1	1.8	-0.8	-0.9	-1.3	1.3	0.9	-1.0	1.0	1.0	-1.1	-1.1
Time in closed arm after self-admin	1.1	1.2	2.1	1.4	1.5	1.1	-1.1	-1.3	1.1	-0.9	-0.9	0.8	0.8
Time in open arm before self-admin	0.9	1.1	1.8	0.8	0.8	1.4	-1.4	-0.9	1.0	-0.9	-1.0	1.0	1.0
Time in open arm after self-admin	0.1	0.1	0.2	-0.2	-0.3	0.0	-0.0	0.1	0.1	-0.3	-0.4	0.4	0.4
Bone: periosteal estimation	0.3	0.6	1.2	-1.1	-1.0	-0.6	0.6	1.0	-0.7	0.7	0.7	-0.6	-0.6
Bone: periosteal perimeter	0.2	0.5	0.9	-1.0	-0.9	-0.6	0.6	0.8	-0.7	0.7	0.6	-0.5	-0.5
Bone: post-yield work	0.6	1.0	1.2	1.0	0.7	1.0	-1.0	-0.9	1.1	-1.1	-1.1	1.0	1.0
Progressive ratio test 1 active lever presses	2.3	4.0	5.4	-2.3	-2.3	-2.1	2.1	2.1	-1.8	1.8	1.7	-1.8	-1.8
Progressive ratio test 1 breakpoint	2.2	3.8	5.6	-2.2	-2.4	-2.0	2.0	2.1	-1.8	1.7	1.6	-1.7	-1.7
Progressive ratio test 1 inactive lever presses	0.9	2.3	3.3	-1.6	-1.8	-1.6	1.6	1.7	-1.2	1.4	1.3	-1.3	-1.3
Progressive ratio test 2 active lever presses	2.5	3.5	4.9	-2.1	-2.1	-2.2	2.2	1.9	-1.8	1.7	1.6	-1.5	-1.5
Progressive ratio test 2 breakpoint	3.0	3.9	5.4	-2.1	-2.2	-2.3	2.3	2.0	-1.9	1.8	1.7	-1.6	-1.6
Progressive ratio test 2 inactive lever presses	0.2	0.8	1.8	-1.0	-1.3	-1.3	1.3	1.0	-0.5	0.5	0.3	-0.3	-0.3
Incentive Sensitization - Responses	0.8	2.1	3.0	-1.6	-1.5	-1.7	1.7	1.5	-1.4	1.3	1.2	-1.1	-1.1
Incentive Sensitization - Breakpoint	0.8	1.9	2.9	-1.5	-1.5	-1.7	1.7	1.4	-1.3	1.2	1.1	-1.1	-1.1
Sum of active levers in priming session hrs 5-6	0.4	0.4	0.8	0.6	0.9	0.7	-0.7	-0.7	0.2	-0.5	-0.5	0.5	0.5
Progressive ratio	0.5	1.5	2.0	1.4	1.1	1.0	-1.0	-1.2	1.1	-1.2	-1.3	1.3	1.3
Food seeking constrained by brief footshock	5.2	6.5	7.4	2.7	2.6	2.4	-2.4	-2.6	2.7	-2.6	-2.6	2.5	2.5
Seeking ratio, punishment vs. effort	0.4	0.8	1.2	0.9	0.9	1.0	-1.0	-0.9	1.1	-0.9	-0.9	0.7	0.7
Retroperitoneal fat weight	0.0	0.1	0.2	-0.3	-0.4	-0.4	0.4	0.4	-0.5	0.3	0.3	-0.3	-0.3
Reaction time number correct	1.9	6.6	8.0	-2.6	-2.2	-2.3	2.3	2.5	-2.6	2.7	2.8	-2.7	-2.7
Reaction time mean minus median	0.1	0.6	1.9	1.1	1.4	0.9	-0.9	-0.9	0.5	-0.4	-0.3	0.2	0.2
Reaction time mean minus median AUC	0.0	0.2	0.4	0.3	0.6	0.2	-0.2	-0.2	-0.2	0.3	0.5	-0.6	-0.6
Reaction time num false alarms	4.3	7.2	8.9	-2.8	-3.0	-2.8	2.8	2.8	-2.7	2.5	2.4	-2.5	-2.5
Reaction time num false alarms AUC	2.8	6.3	8.3	-2.8	-2.9	-2.6	2.6	2.7	-2.6	2.3	2.2	-2.2	-2.2
Reaction time trials correct on left	1.9	6.6	8.0	-2.6	-2.2	-2.3	2.3	2.5	-2.6	2.7	2.8	-2.7	-2.7
Reaction time trials on left	2.0	6.7	8.0	-2.6	-2.3	-2.3	2.3	2.5	-2.6	2.7	2.8	-2.8	-2.8
Reaction time mean	1.0	2.2	3.6	1.9	1.8	1.6	-1.6	-1.7	1.4	-1.4	-1.3	1.0	1.0
Reaction time mean AUC	0.7	1.7	2.7	1.6	1.6	1.5	-1.5	-1.4	1.2	-1.2	-1.1	0.8	0.8
Median of all reaction times	1.4	2.3	3.3	1.8	1.6	1.6	-1.6	-1.6	1.4	-1.5	-1.5	1.1	1.1
Reaction time omissions	0.0	0.0	0.1	0.1	-0.1	-0.0	0.0	0.0	-0.1	0.0	0.0	-0.3	-0.3
Reaction time false alarm rate	0.3	0.4	1.1	-0.8	-1.0	-0.8	0.8	0.8	-0.6	0.4	0.3	-0.3	-0.3
Reaction time premature initiation rate	0.3	0.5	0.9	0.6	0.5	0.8	-0.8	-0.6	0.9	-0.8	-0.8	0.6	0.6
Reaction time premature initiations	0.1	0.4	0.6	-0.7	-0.6	-0.4	0.4	0.6	-0.4	0.6	0.7	-0.8	-0.8
Std. dev. reaction times	0.2	0.7	1.7	1.2	1.3	1.0	-1.0	-1.0	0.6	-0.6	-0.5	0.4	0.4
Reaction time trials completed	2.0	6.7	8.0	-2.6	-2.3	-2.3	2.3	2.5	-2.6	2.7	2.8	-2.8	-2.8
Reaction time trials AUC	2.4	8.2	9.7	-2.9	-2.5	-2.6	2.6	2.8	-2.9	3.0	3.1	-3.0	-3.0
Run reversals in cocaine runway, females	0.2	0.2	0.5	0.3	0.3	0.4	-0.4	-0.4	0.7	-0.5	-0.6	0.5	0.5
Run reversals in cocaine runway, males	0.4	0.5	0.5	-0.6	-0.6	-0.6	0.6	0.7	-0.7	0.7	0.7	-0.7	-0.7
Latency to leave start box in cocaine runway	0.1	0.1	0.3	-0.1	0.3	0.4	-0.4	-0.1	0.2	0.2	0.3	-0.6	-0.6
Latency to leave start box in cocaine runway, F	0.4	0.5	1.1	-0.8	-0.3	-0.2	0.2	0.5	-0.5	0.8	1.0	-1.0	-1.0
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	0.5	0.4	0.4	-0.4	-0.4	0.5	-0.4	-0.3	0.1	0.1
Std. dev. time between licks in bursts	0.0	0.1	0.2	-0.3	-0.4	-0.2	0.2	0.2	-0.2	0.1	0.1	-0.3	-0.3
Total sessions with >9 infusions	3.9	4.9	5.3	-2.3	-2.2	-2.3	2.3	2.2	-2.3	2.2	2.2	-2.1	-2.1
Short access day 1 total inactive lever presses	0.9	1.8	4.1	-1.5	-2.0	-1.7	1.7	1.5	-1.1	0.9	0.7	-0.7	-0.7
Short access day 10 total inactive lever presses	0.2	1.3	1.6	1.2	1.1	1.0	-1.0	-1.1	1.0	-1.2	-1.2	1.2	1.2
Short access day 1 total infusions	1.5	3.0	3.5	-1.8	-1.8	-1.9	1.9	1.7	-1.8	1.6	1.6	-1.6	-1.6
Short access day 10 total infusions	3.3	5.4	6.1	-2.5	-2.5	-2.5	2.5	2.4	-2.3	2.2	2.1	-2.1	-2.1
Short access total infusions	2.5	3.5	4.4	-2.0	-2.1	-2.1	2.1	1.9	-1.9	1.7	1.7	-1.6	-1.6
Short access day 1 locomotion	3.1	5.2	7.1	-2.2	-2.5	-2.7	2.7	2.3	-2.2	2.1	2.0	-2.0	-2.0
Short access day 10 total locomotion	0.0	0.0	0.0	0.0	0.2	0.1	-0.1	-0.1	-0.1	0.1	0.1	-0.1	-0.1
Short access total locomotion	0.8	1.2	1.7	-1.0	-1.2	-1.3	1.3	1.1	-1.1	1.0	0.9	-1.0	-1.0
One hour access (0.3 mA shock)	0.1	0.1	0.2	-0.3	-0.4	-0.3	0.3	0.3	-0.2	0.2	0.2	-0.2	-0.2
Compulsive drug intake	0.1	0.1	0.4	-0.3	-0.1	0.0	-0.0	0.2	-0.3	0.4	0.5	-0.6	-0.6
One hour access (shock baseline)	0.7	1.8	3.0	-1.2	-1.5	-1.7	1.7	1.4	-1.3	1.2	1.1	-1.1	-1.1
Social response proportion	0.8	1.0	1.7	-0.8	-0.8	-0.8	0.8	0.9	-0.9	1.0	1.1	-1.3	-1.3
Social responses	0.8	1.0	1.2	-1.1	-1.0	-0.9	0.9	1.0	-0.9	1.0	1.0	-1.1	-1.1
Social time	2.9	4.6	5.9	1.8	1.7	2.4	-2.4	-1.9	2.4	-2.2	-2.2	2.1	2.1
Soleus weight	0.1	0.4	0.5	-0.7	-0.7	-0.7	0.7	0.7	-0.6	0.6	0.6	-0.6	-0.6
Bone: stiffness	0.7	1.3	1.8	-1.3	-1.2	-1.1	1.1	1.2	-1.1	1.1	1.1	-0.9	-0.9
Tibialis anterior weight	3.6	12.4	14.0	-3.7	-3.7	-3.6	3.6	3.6	-3.4	3.4	3.3	-3.4	-3.4
Time to tail flick, vehicle, before self-admin	2.4	3.0	3.9	-2.0	-1.5	-1.6	1.6	1.7	-1.8	1.8	1.8	-1.8	-1.8
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.4	0.3	0.6	0.5	-0.5	-0.3	0.1	0.1	0.2	-0.1	-0.1
Time to tail flick, test, before self-admin	0.3	0.3	0.7	0.8	0.6	0.3	-0.3	-0.6	0.2	-0.6	-0.6	0.7	0.7
Time to tail flick, test, after self-admin	0.1	0.1	0.2	0.0	-0.0	0.2	-0.2	-0.2	0.5	-0.4	-0.5	0.4	0.4
Delta time to tail flick, vehicle, before/after SA	0.3	0.4	0.7	0.7	0.7	0.9	-0.9	-0.6	0.5	-0.3	-0.3	0.3	0.3
Delta time to tail flick, test, before/after SA	0.7	0.9	1.7	-1.3	-1.1	-0.7	0.7	1.0	-0.6	0.9	0.9	-1.0	-1.0
Tibia length	0.3	0.7	1.1	-0.8	-1.0	-0.9	0.9	0.9	-0.8	0.8	0.7	-0.9	-0.9
Ambulatory time before self-admin	0.0	0.0	0.1	0.1	0.2	0.3	-0.3	-0.2	0.1	-0.1	-0.0	0.1	0.1
Ambulatory time after self-admin	0.4	0.7	1.0	0.7	1.0	0.9	-0.9	-0.9	0.9	-0.7	-0.7	0.7	0.7
Bone: tissue strength	0.8	0.9	0.9	1.0	0.9	0.9	-0.9	-0.9	0.9	-0.9	-0.9	0.9	0.9
Total heroin consumption	0.0	0.0	0.0	-0.2	-0.2	0.2	-0.2	0.1	-0.1	-0.1	-0.1	0.1	0.1
Bone: trabecular number	0.0	0.0	0.1	0.3	0.1	-0.0	0.0	-0.3	0.2	-0.2	-0.2	0.0	0.0
Bone: trabecular spacing	0.0	0.0	0.1	-0.3	-0.1	0.0	-0.0	0.2	-0.1	0.2	0.2	0.0	0.0
Bone: trabecular thickness	1.4	1.9	2.1	-1.3	-1.3	-1.4	1.4	1.3	-1.4	1.3	1.3	-1.4	-1.4
Bone: trabecular tissue density	0.2	0.4	0.6	-0.6	-0.5	-0.5	0.5	0.6	-0.6	0.7	0.7	-0.8	-0.8
Water consumed over 24 hours	0.1	0.2	0.5	0.7	0.7	0.6	-0.6	-0.6	0.5	-0.4	-0.4	0.1	0.1
Number of responses in last shaping day	2.4	3.1	4.8	-1.5	-1.5	-1.8	1.8	1.7	-2.2	1.8	1.9	-1.8	-1.8