Hub : Genes

Snrpd2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Snrpd2 0.15 0.12 2.7e-08 0.06 0.07 0.07 0.07 1.6e-07 7.7e-08 1.6e-08 4.3e-08
2 Adipose isoform ratio NM_001109399.2 0.02 0.02 9.6e-03 0.01 0.01 0.01 0 3.5e-02 4.2e-02 3.9e-02 8.7e-02
3 Adipose alternative TSS NM_001109399.2 0.02 0.02 4.3e-03 0.01 0.01 0.01 0.01 2.0e-02 2.3e-02 3.2e-02 5.8e-02
4 Adipose alternative TSS XM_063273625.1 0.02 0.02 5.8e-03 0.01 0.01 0.01 0 2.9e-02 3.5e-02 4.6e-02 9.2e-02
5 Adipose gene expression Snrpd2 0.27 0.16 0.0e+00 0.19 0.19 0.19 0.19 2.5e-20 2.5e-20 1.8e-20 4.6e-21
6 Brain gene expression Snrpd2 0.09 0.08 5.9e-08 0.07 0.07 0.07 0.07 7.5e-07 2.6e-07 1.9e-07 7.5e-07
7 PL gene expression Snrpd2 0.04 0.03 1.9e-04 0.03 0.04 0.03 0.03 4.6e-04 9.9e-05 2.3e-04 3.4e-04
8 pVTA gene expression Snrpd2 0.05 0.06 9.7e-03 0.01 0.01 0 0.01 6.2e-02 3.8e-02 1.7e-01 8.9e-02
9 LHb gene expression Snrpd2 0.14 0.14 6.2e-03 0.1 0.08 0.09 0.08 2.5e-03 5.4e-03 4.8e-03 7.3e-03
10 NAcc gene expression Snrpd2 0.05 0.04 1.5e-07 0.04 0.04 0.04 0.04 2.8e-07 3.5e-07 1.2e-06 1.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.00.00.0-0.00.20.2-0.2-0.00.0-0.0-0.00.10.1
Area under the delay curve1.51.82.7-1.0-1.0-1.31.3-1.2-1.4-1.4-1.4-1.6-1.6
BMI with tail0.82.64.01.72.01.7-1.71.71.51.41.31.51.5
BMI without tail1.03.15.62.02.41.9-1.92.01.61.51.31.31.3
Body weight1.56.610.22.83.22.7-2.72.82.52.32.12.22.2
Weight adjusted by age0.00.00.1-0.00.10.4-0.40.0-0.00.00.0-0.0-0.0
Bone surface0.30.60.80.80.90.8-0.80.80.60.60.60.80.8
Bone volume0.20.40.50.60.70.7-0.70.60.50.50.50.70.7
Breakpoint value in progressive ratio session2.42.93.5-1.9-1.8-1.71.7-1.7-1.5-1.6-1.6-1.7-1.7
Number of licking bursts2.33.74.82.21.92.0-2.02.02.12.02.01.51.5
Context. condit. distance diff. score0.10.10.20.10.10.1-0.10.20.30.40.40.40.4
Locomotion velocity, session 10.10.10.3-0.6-0.5-0.20.2-0.4-0.2-0.2-0.2-0.4-0.4
Locomotion distance, session 10.00.00.2-0.2-0.20.0-0.0-0.1-0.10.10.20.40.4
Locomotion velocity, session 21.41.72.31.51.51.3-1.31.41.31.31.21.01.0
Locomotion distance, session 20.30.40.80.50.60.6-0.60.60.40.60.60.90.9
Locomotion velocity, session 30.30.30.50.70.70.5-0.50.60.50.50.50.50.5
Locomotion distance, session 30.70.81.1-0.7-0.7-1.01.0-0.8-1.1-0.9-0.9-0.8-0.8
Stereotopy head waving bouts, day 30.91.11.41.21.01.1-1.11.11.21.11.10.70.7
Stereotopy head waving duration, day 30.91.11.41.00.91.0-1.01.01.11.11.21.01.0
Locomotion velocity, session 70.20.20.5-0.7-0.5-0.60.6-0.5-0.5-0.4-0.4-0.1-0.1
Locomotion distance, session 70.00.00.10.10.30.0-0.00.20.00.10.10.30.3
Stereotopy head waving bouts, day 70.91.01.40.90.81.1-1.10.91.21.11.11.01.0
Stereotopy head waving duration, day 70.80.91.21.00.81.1-1.10.91.11.01.00.80.8
Locomotion velocity, session 80.00.00.0-0.1-0.1-0.20.2-0.1-0.1-0.1-0.0-0.1-0.1
Locomotion distance, session 80.00.00.2-0.10.0-0.10.10.0-0.10.10.10.40.4
Degree of sensitization distance0.50.60.60.70.70.7-0.70.80.80.80.80.80.8
Degree of sensitization stereotypy1.11.11.50.90.91.2-1.20.91.21.11.11.01.0
Conditioned locomotion0.00.00.1-0.3-0.3-0.20.2-0.3-0.2-0.2-0.2-0.1-0.1
Cocaine response after cond. corrected0.50.61.10.70.60.6-0.60.70.80.80.81.01.0
Cocaine response after cond. not corrected1.41.72.41.21.21.1-1.11.21.31.31.31.51.5
Cocaine response before conditioning1.72.02.31.41.51.5-1.51.41.51.41.41.31.3
Saline control response2.12.83.11.81.61.7-1.71.71.71.71.71.61.6
Bone: connectivity density0.00.00.1-0.10.10.1-0.1-0.1-0.2-0.2-0.20.10.1
Bone: cortical apparent density0.00.10.2-0.5-0.2-0.10.1-0.3-0.2-0.3-0.3-0.1-0.1
Bone: cortical area1.62.43.41.91.61.4-1.41.61.61.61.61.41.4
Bone: cortical porosity0.20.20.4-0.2-0.4-0.60.6-0.3-0.4-0.4-0.4-0.6-0.6
Bone: cortical porosity0.00.00.10.30.1-0.20.20.10.1-0.0-0.0-0.2-0.2
Bone: cortical thickness0.60.91.21.10.90.9-0.91.01.01.01.01.01.0
Bone: cortical thickness1.41.61.81.31.21.3-1.31.21.31.31.31.31.3
Bone: cortical tissue density0.10.10.4-0.6-0.3-0.20.2-0.4-0.3-0.4-0.4-0.2-0.2
Condit. Reinf. active minus inactive responses0.50.60.80.80.90.8-0.80.70.80.70.60.80.8
Condit. Reinf. active-inactive response ratio0.40.50.60.60.80.7-0.70.60.70.60.50.80.8
Condit. Reinf. active responses0.30.40.70.60.70.6-0.60.60.60.50.50.80.8
Condit. Reinf. inactive responses0.10.10.2-0.4-0.4-0.40.4-0.3-0.4-0.2-0.20.20.2
Incentive salience index mean0.40.50.80.80.90.8-0.80.70.70.50.50.60.6
Condit. Reinf. lever presses0.10.10.40.40.60.4-0.40.40.30.10.10.20.2
Condit. Reinf. active minus inactive responses0.00.10.20.00.00.1-0.10.10.20.30.30.40.4
Condit. Reinf. active-inactive response ratio0.30.30.80.30.20.4-0.40.40.50.60.70.90.9
Condit. Reinf. active responses0.10.10.2-0.4-0.4-0.40.4-0.4-0.3-0.3-0.3-0.3-0.3
Condit. Reinf. inactive responses0.70.91.1-0.9-0.9-0.90.9-0.9-0.8-0.9-0.9-1.0-1.0
Condit. Reinf. lever presses0.10.10.20.40.40.2-0.20.40.30.40.40.40.4
Condit. Reinf. lever reinforcers received0.10.20.2-0.4-0.5-0.50.5-0.4-0.4-0.4-0.3-0.4-0.4
Conditioned reinforcement - actives1.62.73.61.81.91.9-1.91.71.41.51.41.51.5
Conditioned reinforcement - inactives0.71.12.41.21.61.2-1.21.20.70.80.70.70.7
Conditioned locomotion2.22.94.11.41.42.0-2.01.51.71.71.81.71.7
Patch foraging indifference point 0 sec0.30.50.90.60.40.3-0.30.60.70.90.90.80.8
Patch foraging indifference point AUC3.85.47.22.52.62.7-2.72.42.32.12.01.91.9
Delay disc. indifference point, 0s delay1.01.11.7-0.9-0.7-0.90.9-0.9-1.1-1.2-1.2-1.3-1.3
Delay disc. indifference point, 16s delay1.01.11.6-0.7-0.6-1.01.0-0.9-1.1-1.1-1.1-1.2-1.2
Delay disc. indifference point, 2s delay3.13.45.7-1.5-1.3-1.51.5-1.6-1.9-2.0-2.0-2.4-2.4
Delay disc. indifference point, 24s delay0.00.00.10.2-0.0-0.20.20.00.10.20.30.30.3
Delay disc. indifference point, 4s delay0.00.00.00.00.10.1-0.10.00.0-0.0-0.0-0.2-0.2
Delay disc. indifference point, 8s delay1.61.92.4-1.3-1.3-1.31.3-1.3-1.3-1.4-1.4-1.6-1.6
Indifference point function ln k1.42.54.4-1.6-1.9-2.12.1-1.7-1.5-1.2-1.1-1.0-1.0
Indifference point function log k1.42.54.4-1.6-1.9-2.12.1-1.7-1.5-1.2-1.1-1.0-1.0
Patch foraging total patch changes 0 sec0.40.81.30.80.60.5-0.50.80.91.11.21.11.1
Patch foraging total patch changes 12 sec1.92.43.41.81.81.7-1.71.71.61.41.31.21.2
Patch foraging total patch changes 18 sec2.03.13.61.51.51.9-1.91.61.91.71.81.81.8
Patch foraging total patch changes 24 sec0.61.02.10.91.11.4-1.41.00.90.80.70.80.8
Patch foraging total patch changes 6 sec2.33.53.92.01.81.6-1.61.92.01.92.01.91.9
Patch foraging time to switch 0 sec2.44.96.6-2.2-2.1-1.91.9-2.2-2.1-2.3-2.3-2.6-2.6
Patch foraging water rate 0 sec2.75.76.72.52.32.1-2.12.42.32.52.52.62.6
Patch foraging water rate 12 sec0.10.20.50.50.40.3-0.30.40.30.50.50.70.7
Patch foraging water rate 18 sec0.10.20.30.50.50.3-0.30.50.10.40.40.60.6
Patch foraging water rate 24 sec0.40.61.00.60.40.5-0.50.60.80.90.91.01.0
Patch foraging water rate 6 sec0.71.01.51.01.01.0-1.01.00.81.01.01.21.2
Seeking ratio, delayed vs. immediate footshock2.02.43.2-1.8-1.7-1.51.5-1.6-1.5-1.5-1.5-1.4-1.4
Distance traveled before self-admin0.00.00.10.10.10.1-0.10.20.00.30.30.30.3
Distance traveled after self-admin0.30.30.6-0.5-0.8-0.60.6-0.6-0.7-0.5-0.4-0.4-0.4
Extensor digitorum longus weight2.08.09.43.13.03.1-3.12.92.82.72.72.42.4
Bone: elastic displacement0.70.91.1-1.0-0.9-0.80.8-1.0-0.8-1.0-1.0-1.0-1.0
Bone: elastic work0.10.10.20.40.40.3-0.30.30.30.20.10.10.1
Bone: endosteal estimation0.00.00.10.00.2-0.20.20.0-0.2-0.2-0.3-0.2-0.2
Bone: endosteal perimeter0.00.00.00.10.1-0.20.20.1-0.0-0.0-0.0-0.1-0.1
Epididymis fat weight0.20.60.9-0.7-0.5-0.60.6-0.7-0.8-0.9-0.9-1.0-1.0
Delta time in closed arm before/after self-admin0.50.40.9-0.9-0.9-0.90.9-0.7-0.5-0.3-0.2-0.2-0.2
Delta time in open arm before/after self-admin0.10.10.40.40.50.6-0.60.30.0-0.1-0.2-0.2-0.2
Diff in mean of infusions in LGA sessions1.41.82.7-1.5-1.6-1.11.1-1.5-1.1-1.3-1.3-1.3-1.3
Delay discount exponential model param1.21.32.00.80.81.1-1.11.01.21.21.21.41.4
Extinction: sum of active levers before priming0.10.10.1-0.2-0.2-0.30.3-0.10.2-0.2-0.2-0.3-0.3
Active lever presses in extinction session 60.10.10.30.60.60.3-0.30.50.40.30.20.20.2
Bone: final force0.40.71.11.01.00.8-0.80.90.90.80.80.60.6
Bone: final moment0.61.01.61.31.20.9-0.91.11.11.00.90.70.7
Food consumed during 24 hour testing period5.06.98.0-2.8-2.7-2.62.6-2.7-2.7-2.7-2.6-2.4-2.4
Glucose0.40.61.0-1.0-1.0-0.80.8-0.8-0.7-0.6-0.6-0.8-0.8
Heart weight2.03.03.51.81.61.7-1.71.81.81.81.91.71.7
Delay discount hyperbolic model param1.01.21.90.80.81.0-1.01.01.11.11.11.41.4
Intermittent access intake day 1-15 change0.10.20.30.60.50.4-0.40.40.40.40.40.40.4
Intermittent access intake escalation0.10.30.50.70.70.5-0.50.60.50.50.50.50.5
Intermittent access intake escalation 20.00.00.2-0.1-0.3-0.40.4-0.2-0.00.00.10.10.1
Intermitt. access day 1 inactive lever presses0.00.10.20.20.50.3-0.30.30.10.10.00.00.0
Intermitt. access day 15 inactive lever presses0.00.10.3-0.20.20.6-0.60.2-0.10.10.00.00.0
Intermitt. access escalation Index0.20.30.4-0.6-0.6-0.50.5-0.6-0.4-0.5-0.5-0.5-0.5
Intermittent access day 1 total infusions2.03.24.52.02.12.0-2.01.91.51.61.51.51.5
Intermittent access day 15 total infusions1.11.72.81.31.41.7-1.71.31.11.11.01.01.0
Intermittent access terminal intake (last 3 days)1.41.82.51.31.41.6-1.61.31.31.21.21.21.2
Intermittent access total infusions3.03.54.81.81.92.2-2.21.91.91.71.71.71.7
Intermittent access day 1 locomotion0.50.61.10.71.01.1-1.10.80.60.60.60.60.6
Intermittent access day 15 total locomotion0.20.30.50.50.60.7-0.70.60.30.50.50.50.5
Intermittent access total locomotion1.92.33.01.51.61.7-1.71.51.31.41.41.41.4
Intermittent access standard deviation0.10.20.3-0.5-0.5-0.40.4-0.5-0.4-0.5-0.4-0.5-0.5
Left kidney weight6.027.831.05.55.65.1-5.15.45.25.15.05.45.4
Right kidney weight5.424.726.55.15.24.8-4.85.05.14.84.85.15.1
Cocaine induced anxiety0.10.20.3-0.6-0.00.3-0.3-0.2-0.4-0.5-0.5-0.6-0.6
Post-drug Anxiety0.00.00.1-0.3-0.10.1-0.1-0.1-0.1-0.2-0.2-0.3-0.3
Baseline Anxiety0.30.31.0-0.5-1.0-0.80.8-0.60.0-0.00.10.00.0
Tail length0.51.93.71.71.91.4-1.41.61.31.21.10.90.9
Length with tail0.52.03.51.71.91.5-1.51.61.41.21.21.11.1
Length without tail0.41.31.61.11.21.3-1.31.11.21.01.01.11.1
Times rat made contact with spout0.10.10.2-0.4-0.4-0.40.4-0.3-0.2-0.1-0.10.20.2
Lifetime Intake3.13.75.21.92.12.3-2.31.91.91.71.71.71.7
Liver weight, left2.33.84.72.22.12.0-2.02.02.01.91.91.71.7
Liver weight, right1.83.14.41.82.11.8-1.81.81.81.51.51.61.6
Locomotor activity1.93.03.61.91.61.6-1.61.81.81.91.91.61.6
Locomotor testing distance1.12.02.51.61.41.5-1.51.51.21.41.41.31.3
Locomotor testing rearing4.59.19.93.23.13.1-3.13.13.03.02.92.92.9
Locomotion in novel chamber0.50.61.5-0.5-1.0-1.21.2-0.8-0.5-0.5-0.4-0.4-0.4
Locomotion in novel chamber post-restriction1.01.72.6-1.2-1.3-1.61.6-1.2-1.4-1.2-1.2-1.1-1.1
Fecal boli incidents, locomotor time 10.10.10.30.50.40.1-0.10.40.20.20.20.10.1
Change in fecal boli incidents, locomotor task0.70.71.1-0.8-0.6-0.70.7-0.7-0.8-0.9-0.9-1.1-1.1
Time >=10cm from walls, locomotor time 10.00.00.1-0.1-0.0-0.00.0-0.0-0.1-0.0-0.00.30.3
Bouts of movement, locomotor time 12.42.73.7-1.9-1.6-1.71.7-1.7-1.7-1.6-1.6-1.5-1.5
Total resting periods, locomotor time 13.03.44.4-2.1-1.8-1.81.8-1.9-1.9-1.9-1.8-1.7-1.7
Rest time, locomotor task time 10.20.20.3-0.6-0.4-0.50.5-0.4-0.5-0.5-0.5-0.3-0.3
Distance moved, locomotor task time 10.40.50.70.90.70.8-0.80.70.80.70.70.50.5
Vertical activity count, locomotor time 10.00.10.10.40.40.3-0.30.20.2-0.0-0.1-0.3-0.3
Time >=10cm from walls, locomotor time 20.10.10.2-0.1-0.1-0.30.3-0.2-0.3-0.3-0.3-0.4-0.4
Bouts of movement, locomotor time 25.08.010.6-3.3-3.1-2.82.8-3.0-2.8-2.7-2.6-2.5-2.5
Total resting periods, locomotor time 24.27.310.2-3.2-3.1-2.72.7-2.9-2.7-2.6-2.5-2.3-2.3
Rest time, locomotor task time 20.10.10.5-0.7-0.5-0.30.3-0.4-0.2-0.2-0.10.10.1
Distance moved, locomotor task time 20.81.01.71.31.20.9-0.91.11.01.00.90.60.6
Vertical activity count, locomotor time 20.10.10.40.40.4-0.00.00.1-0.1-0.3-0.4-0.6-0.6
Light reinforcement 10.10.20.20.40.50.5-0.50.40.20.40.40.50.5
Light reinforcement 20.30.41.00.81.00.8-0.80.80.40.30.20.30.3
Bone: marrow area0.00.00.10.10.3-0.20.20.1-0.1-0.2-0.2-0.2-0.2
Bone: maximum diameter2.34.35.42.32.21.9-1.92.22.12.12.02.02.0
Bone: maximum force0.20.30.60.80.70.5-0.50.60.60.50.50.40.4
Bone: maximum moment0.20.40.90.90.90.5-0.50.80.70.60.60.40.4
Mean time between licks in bursts0.00.10.1-0.1-0.1-0.20.2-0.2-0.2-0.3-0.3-0.4-0.4
Mean num. licks in bursts2.84.36.2-2.5-2.2-2.32.3-2.2-2.3-2.0-2.0-1.3-1.3
Cd content in liver0.20.20.6-0.8-0.7-0.20.2-0.5-0.3-0.2-0.2-0.0-0.0
Co content in liver1.21.41.8-1.3-1.2-1.01.0-1.2-1.1-1.2-1.2-1.3-1.3
Cu content in liver0.40.50.80.80.80.9-0.90.70.70.60.60.40.4
Fe content in liver4.45.46.72.32.02.5-2.52.32.62.52.52.02.0
K content in liver0.30.31.21.10.80.5-0.50.70.40.40.3-0.0-0.0
Mg content in liver0.70.71.51.21.10.8-0.81.00.80.80.70.40.4
Mn content in liver1.11.22.01.41.31.1-1.11.21.11.01.01.01.0
Na content in liver0.10.10.30.60.20.4-0.40.40.40.40.50.00.0
Rb content in liver0.10.10.30.20.20.1-0.10.20.20.30.30.50.5
Se content in liver3.94.66.02.42.32.2-2.22.32.32.22.11.71.7
Sr content in liver0.00.00.10.20.20.2-0.20.20.20.20.2-0.2-0.2
Zn content in liver1.01.12.01.41.31.1-1.11.21.00.90.90.70.7
Bone: minimum diameter0.20.40.70.90.80.5-0.50.70.50.60.60.40.4
Time in familiar zone, hab. session 10.10.10.20.40.20.2-0.20.30.30.40.40.30.3
Time in novel zone, hab. session 10.70.71.00.90.91.0-1.00.81.00.80.80.70.7
Total zone transitions, hab. session 10.10.20.50.20.20.4-0.40.30.30.40.50.70.7
Total locomotion distance, hab. session 10.40.50.7-0.7-0.7-0.70.7-0.7-0.8-0.7-0.7-0.8-0.8
Locomotion velocity, hab. session 11.21.72.0-1.3-1.2-1.21.2-1.3-1.4-1.3-1.3-1.3-1.3
Time in familiar zone, hab. session 20.30.30.50.50.60.7-0.70.60.70.60.50.30.3
Time in novel zone, hab. session 20.20.20.3-0.4-0.6-0.60.6-0.4-0.4-0.2-0.2-0.1-0.1
Total zone transitions, hab. session 20.40.60.70.80.70.8-0.80.70.80.80.80.60.6
Total locomotion distance, hab. session 20.50.71.0-0.7-0.8-0.70.7-0.8-0.8-0.8-0.8-1.0-1.0
Locomotion velocity, hab. session 20.30.40.6-0.5-0.6-0.60.6-0.6-0.7-0.7-0.7-0.8-0.8
Novel to familiar place preference ratio0.60.71.80.60.70.6-0.60.70.50.80.81.31.3
Novelty place preference0.50.61.60.50.60.5-0.50.60.40.70.81.21.2
Time in novel zone, NPP test0.60.71.70.60.60.5-0.50.70.50.80.91.31.3
Total zone transitions, NPP test0.10.10.20.40.30.2-0.20.40.20.40.40.40.4
Total locomotion distance, NPP test0.10.10.20.20.10.1-0.10.20.20.30.40.40.4
Locomotion velocity, NPP test0.00.10.20.20.10.1-0.10.20.10.30.30.40.4
Intraocular pressure0.10.10.5-0.4-0.7-0.50.5-0.4-0.0-0.1-0.0-0.2-0.2
Delta distance traveled before/after self-admin1.31.42.2-0.9-0.8-1.01.0-1.0-1.3-1.4-1.5-1.4-1.4
Delta ambulatory time before/after self-admin0.30.30.6-0.3-0.3-0.40.4-0.5-0.8-0.7-0.7-0.7-0.7
Parametrial fat weight0.10.20.40.60.60.4-0.40.50.50.40.30.50.5
Pavlov. Cond. lever latency0.60.81.0-0.8-0.9-1.01.0-0.8-0.9-0.8-0.8-0.8-0.8
Pavlov. Cond. magazine entry latency0.10.10.20.40.40.4-0.40.30.40.30.30.30.3
Pavlov. Cond. change in total contacts0.50.50.8-0.9-0.7-0.60.6-0.8-0.7-0.8-0.8-0.6-0.6
Pavlov. Cond. index score0.30.40.50.60.60.7-0.70.60.70.60.50.60.6
Pavlov. Cond. latency score0.10.10.20.30.30.5-0.50.30.40.30.20.20.2
Pavlov. Cond. lever contacts0.40.50.70.70.70.8-0.80.70.70.60.60.60.6
Pavlov. Cond. magazine entry number0.00.00.1-0.3-0.2-0.30.3-0.1-0.3-0.1-0.1-0.1-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.20.10.10.3-0.30.20.30.30.30.50.5
Pavlov. Cond. lever-magazine prob. diff.0.30.40.50.60.60.7-0.70.60.70.60.60.60.6
Pavlov. Cond. response bias1.01.21.41.21.21.1-1.11.01.11.01.01.11.1
Pavlov. Cond. lever latency0.00.00.0-0.2-0.2-0.10.1-0.2-0.1-0.1-0.1-0.0-0.0
Pavlov. Cond. magazine entry latency0.00.10.3-0.20.10.1-0.10.10.10.10.10.50.5
Pavlov. Cond. change in total contacts0.20.40.6-0.6-0.7-0.70.7-0.7-0.7-0.5-0.5-0.4-0.4
Pavlov. Cond. index score0.00.00.1-0.2-0.1-0.20.2-0.2-0.2-0.2-0.20.10.1
Pavlov. Cond. latency score0.10.10.1-0.3-0.2-0.30.3-0.3-0.3-0.3-0.3-0.1-0.1
Pavlov. Cond. lever contacts0.10.10.20.40.40.2-0.20.40.30.30.30.30.3
Pavlov. Cond. magazine entry number0.30.40.60.80.60.6-0.60.60.70.60.60.30.3
Pavlov. Cond. intertrial magazine entries0.00.00.00.0-0.10.0-0.0-0.00.00.10.10.10.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.0-0.10.0-0.00.00.0-0.00.00.00.20.2
Pavlov. Cond. response bias0.00.00.0-0.1-0.0-0.10.1-0.0-0.1-0.1-0.10.10.1
Time in closed arm before self-admin0.91.11.80.80.91.3-1.30.91.01.01.01.11.1
Time in closed arm after self-admin1.21.32.2-1.5-1.5-1.11.1-1.3-1.1-0.9-0.9-0.8-0.8
Time in open arm before self-admin1.01.11.8-0.8-0.8-1.41.4-0.9-1.0-0.9-1.0-1.0-1.0
Time in open arm after self-admin0.10.10.20.20.3-0.00.00.1-0.1-0.3-0.4-0.4-0.4
Bone: periosteal estimation0.30.61.21.11.00.6-0.61.00.70.70.70.60.6
Bone: periosteal perimeter0.30.50.91.00.90.6-0.60.80.70.70.60.50.5
Bone: post-yield work0.71.01.2-1.0-0.7-1.01.0-0.9-1.1-1.1-1.1-1.0-1.0
Progressive ratio test 1 active lever presses3.24.05.42.32.32.1-2.12.11.81.81.71.81.8
Progressive ratio test 1 breakpoint3.13.85.62.32.42.0-2.02.11.81.71.61.71.7
Progressive ratio test 1 inactive lever presses1.62.33.31.61.81.6-1.61.71.21.41.31.31.3
Progressive ratio test 2 active lever presses3.03.54.92.12.12.2-2.21.91.81.71.61.51.5
Progressive ratio test 2 breakpoint3.43.95.42.12.22.3-2.32.01.91.81.71.61.6
Progressive ratio test 2 inactive lever presses0.50.81.81.11.31.3-1.31.00.50.50.30.30.3
Incentive Sensitization - Responses1.52.13.01.71.51.7-1.71.51.41.31.21.11.1
Incentive Sensitization - Breakpoint1.51.92.91.51.51.7-1.71.41.31.21.11.11.1
Sum of active levers in priming session hrs 5-60.40.40.8-0.6-0.9-0.70.7-0.7-0.2-0.5-0.5-0.5-0.5
Progressive ratio1.01.52.0-1.4-1.1-1.01.0-1.2-1.1-1.2-1.3-1.3-1.3
Food seeking constrained by brief footshock5.36.57.5-2.7-2.6-2.42.4-2.6-2.7-2.6-2.6-2.5-2.5
Seeking ratio, punishment vs. effort0.60.81.2-0.9-0.9-1.01.0-0.9-1.1-0.9-0.9-0.7-0.7
Retroperitoneal fat weight0.00.10.20.30.40.4-0.40.40.50.30.30.30.3
Reaction time number correct3.56.68.02.62.22.3-2.32.52.62.72.82.72.7
Reaction time mean minus median0.30.61.9-1.2-1.4-0.90.9-0.9-0.5-0.4-0.3-0.2-0.2
Reaction time mean minus median AUC0.10.20.4-0.4-0.6-0.20.2-0.20.20.30.50.60.6
Reaction time num false alarms5.17.28.92.83.02.8-2.82.82.72.52.42.52.5
Reaction time num false alarms AUC4.16.38.32.82.92.6-2.62.72.62.32.22.22.2
Reaction time trials correct on left3.56.68.02.62.22.3-2.32.52.62.72.82.72.7
Reaction time trials on left3.56.78.02.62.32.3-2.32.52.62.72.82.82.8
Reaction time mean1.42.33.7-1.9-1.8-1.61.6-1.7-1.4-1.4-1.3-1.0-1.0
Reaction time mean AUC1.11.72.8-1.7-1.6-1.51.5-1.4-1.2-1.2-1.1-0.8-0.8
Median of all reaction times1.62.33.3-1.8-1.6-1.61.6-1.6-1.4-1.5-1.5-1.1-1.1
Reaction time omissions0.00.00.1-0.10.10.0-0.00.00.10.00.00.30.3
Reaction time false alarm rate0.30.51.10.81.00.8-0.80.80.60.40.30.30.3
Reaction time premature initiation rate0.40.50.9-0.6-0.5-0.80.8-0.6-0.9-0.8-0.8-0.6-0.6
Reaction time premature initiations0.20.40.60.70.60.4-0.40.60.40.60.70.80.8
Std. dev. reaction times0.40.71.7-1.2-1.3-1.01.0-1.0-0.6-0.6-0.5-0.4-0.4
Reaction time trials completed3.56.78.02.62.32.3-2.32.52.62.72.82.82.8
Reaction time trials AUC4.38.29.72.92.52.6-2.62.82.93.03.13.03.0
Run reversals in cocaine runway, females0.20.20.5-0.3-0.3-0.40.4-0.4-0.7-0.5-0.6-0.5-0.5
Run reversals in cocaine runway, males0.50.50.50.60.60.6-0.60.70.70.70.70.70.7
Latency to leave start box in cocaine runway0.10.10.30.1-0.3-0.40.4-0.1-0.20.20.30.60.6
Latency to leave start box in cocaine runway, F0.40.51.10.80.30.2-0.20.50.50.81.01.01.0
Latency to leave start box in cocaine runway, M0.10.10.2-0.5-0.4-0.40.4-0.4-0.5-0.4-0.3-0.1-0.1
Std. dev. time between licks in bursts0.00.10.20.30.40.2-0.20.20.20.10.10.30.3
Total sessions with >9 infusions4.04.95.32.32.22.3-2.32.22.32.22.22.12.1
Short access day 1 total inactive lever presses1.41.84.11.52.01.7-1.71.51.10.90.70.70.7
Short access day 10 total inactive lever presses0.51.31.6-1.2-1.1-1.01.0-1.1-1.0-1.2-1.2-1.2-1.2
Short access day 1 total infusions2.33.03.51.81.81.9-1.91.71.81.61.61.61.6
Short access day 10 total infusions4.25.46.12.52.52.5-2.52.42.32.22.12.12.1
Short access total infusions2.83.54.42.12.12.1-2.11.91.91.71.71.61.6
Short access day 1 locomotion4.25.27.12.22.52.7-2.72.32.22.12.02.02.0
Short access day 10 total locomotion0.00.00.0-0.0-0.2-0.10.1-0.10.10.10.10.10.1
Short access total locomotion1.01.21.71.01.21.3-1.31.11.11.00.91.01.0
One hour access (0.3 mA shock)0.10.10.20.30.40.3-0.30.30.20.20.20.20.2
Compulsive drug intake0.10.10.40.20.1-0.00.00.20.30.40.50.60.6
One hour access (shock baseline)1.21.83.01.21.51.7-1.71.41.31.21.11.11.1
Social response proportion0.91.01.70.80.80.8-0.80.90.91.01.11.31.3
Social responses0.81.01.21.11.00.9-0.91.00.91.01.01.11.1
Social time3.44.65.9-1.8-1.7-2.42.4-1.9-2.4-2.2-2.2-2.1-2.1
Soleus weight0.10.40.50.70.70.7-0.70.70.60.60.60.60.6
Bone: stiffness0.81.31.81.41.21.1-1.11.21.11.11.10.90.9
Tibialis anterior weight3.712.414.03.73.73.6-3.63.63.43.43.33.43.4
Time to tail flick, vehicle, before self-admin2.93.03.92.01.51.6-1.61.71.81.81.81.81.8
Time to tail flick, vehicle, after self-admin0.10.10.4-0.3-0.6-0.50.5-0.3-0.10.10.20.10.1
Time to tail flick, test, before self-admin0.30.30.7-0.8-0.6-0.30.3-0.6-0.2-0.6-0.6-0.7-0.7
Time to tail flick, test, after self-admin0.10.10.20.00.0-0.20.2-0.2-0.5-0.4-0.5-0.4-0.4
Delta time to tail flick, vehicle, before/after SA0.40.40.7-0.7-0.7-0.90.9-0.6-0.5-0.3-0.3-0.3-0.3
Delta time to tail flick, test, before/after SA0.80.91.71.31.10.7-0.71.00.60.90.91.01.0
Tibia length0.30.71.10.81.00.9-0.90.90.80.80.70.90.9
Ambulatory time before self-admin0.00.00.1-0.1-0.2-0.30.3-0.2-0.1-0.1-0.0-0.1-0.1
Ambulatory time after self-admin0.60.71.0-0.7-1.0-0.90.9-0.9-0.9-0.7-0.7-0.7-0.7
Bone: tissue strength0.90.90.9-1.0-0.9-0.90.9-0.9-0.9-0.9-0.9-0.9-0.9
Total heroin consumption0.00.00.10.20.2-0.20.20.10.1-0.1-0.1-0.1-0.1
Bone: trabecular number0.00.00.1-0.3-0.10.0-0.0-0.3-0.2-0.2-0.2-0.0-0.0
Bone: trabecular spacing0.00.00.10.30.1-0.00.00.20.10.20.2-0.0-0.0
Bone: trabecular thickness1.51.92.11.31.31.4-1.41.31.41.31.31.41.4
Bone: trabecular tissue density0.30.40.60.60.50.5-0.50.60.60.70.70.80.8
Water consumed over 24 hours0.20.30.5-0.7-0.7-0.60.6-0.6-0.5-0.4-0.4-0.1-0.1
Number of responses in last shaping day2.93.14.81.41.51.8-1.81.72.21.81.91.81.8