Hub : Genes

Snrpc

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr20_5897866_5898164 0.39 0.1 0.0e+00 0.19 0.18 0.21 0.2 1.8e-20 2.7e-19 2.5e-23 1.3e-21
2 Liver gene expression Snrpc 0.76 0.07 0.0e+00 0.23 0.27 0.3 0.28 3.1e-25 7.1e-30 1.1e-33 7.4e-31
3 Liver isoform ratio XM_039098816.2 0.37 0.1 0.0e+00 0.17 0.18 0.22 0.17 2.3e-18 8.0e-20 9.3e-24 5.1e-19
4 Liver intron excision ratio chr20_5897976_5898164 0.52 0.1 0.0e+00 0.23 0.29 0.36 0.27 1.6e-25 5.0e-32 3.8e-42 2.9e-30
5 Liver alternative TSS XM_039098816.2 0.52 0.12 0.0e+00 0.18 0.28 0.33 0.19 2.0e-19 1.6e-30 3.7e-37 2.4e-20
6 Liver isoform ratio NM_001271040.1 0.28 0.1 5.1e-11 0.1 0.09 0.1 0.11 5.2e-11 2.0e-10 4.6e-11 4.1e-12
7 Adipose gene expression Snrpc 0.19 0.07 6.5e-10 0.07 0.07 0.07 0.08 4.8e-08 1.7e-08 2.5e-08 3.2e-09
8 Liver alternative TSS XM_063279219.1 0.2 0.07 0.0e+00 0.16 0.18 0.19 0.16 3.8e-17 4.2e-19 2.7e-20 1.1e-17
9 Liver intron excision ratio chr20_5890395_5891581 0.21 0.09 3.1e-14 0.09 0.09 0.1 0.09 3.2e-10 4.4e-10 1.2e-10 6.3e-10
10 PL alternative TSS XM_063279218.1 0.03 0.02 8.9e-03 0.03 0.01 0.01 0.02 5.0e-04 2.5e-02 1.9e-02 2.1e-03
11 Liver isoform ratio XM_063279219.1 0.06 0.03 2.1e-09 0.07 0.08 0.07 0.05 5.8e-08 6.9e-09 2.9e-08 2.0e-06
12 Liver alternative TSS XM_039098816.2 0.39 0.11 0.0e+00 0.29 0.31 0.35 0.29 1.9e-32 2.0e-35 5.2e-40 6.3e-33
13 Liver alternative TSS NM_001271040.1 0.4 0.11 0.0e+00 0.26 0.32 0.35 0.31 2.2e-29 7.4e-36 1.5e-40 2.3e-35
14 Liver intron excision ratio chr20_5890395_5897641 0.11 0.06 8.2e-06 0.01 0.02 0.02 0.01 3.9e-02 3.4e-03 5.9e-03 1.8e-02
15 Liver alternative TSS NM_001271040.1 0.1 0.05 5.8e-08 0.03 0.06 0.06 0.06 4.1e-04 1.9e-07 1.8e-07 7.9e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.10.21.6-0.40.40.30.70.20.3-0.3-0.1-0.71.3-0.00.2-0.1-0.6-0.3
Area under the delay curve0.10.10.50.3-0.1-0.3-0.3-0.3-0.7-0.20.1-0.7-0.30.00.2-0.1-0.30.0
BMI with tail2.79.313.0-3.23.23.33.43.61.7-3.2-3.6-3.2-2.33.1-3.02.9-3.02.2
BMI without tail0.84.17.9-1.82.01.91.72.30.8-1.8-2.6-0.9-2.82.2-2.52.4-1.41.9
Body weight1.25.516.01.5-0.7-1.1-1.20.0-3.2-0.3-1.5-0.7-3.42.7-3.53.3-2.44.0
Weight adjusted by age0.41.13.61.4-0.8-1.2-1.6-0.9-1.90.50.30.5-1.50.1-1.00.9-0.21.1
Bone surface0.51.02.11.4-1.2-1.4-1.2-1.3-1.31.11.00.91.0-0.50.4-0.40.20.1
Bone volume0.10.20.50.5-0.3-0.6-0.3-0.5-0.70.20.30.00.7-0.00.0-0.0-0.30.1
Breakpoint value in progressive ratio session0.30.51.0-0.60.50.51.00.80.2-0.5-0.6-0.60.91.0-0.60.7-0.70.6
Number of licking bursts0.41.42.40.9-1.5-1.0-1.0-1.1-0.31.61.21.41.1-1.01.3-1.41.1-1.0
Context. condit. distance diff. score3.64.411.62.0-2.4-2.0-1.7-2.4-1.32.02.51.33.4-2.02.3-2.21.3-1.6
Locomotion velocity, session 12.02.23.91.3-1.2-1.5-1.6-1.7-0.41.61.61.71.0-2.01.5-1.51.7-1.5
Locomotion distance, session 11.01.34.2-0.50.30.2-0.0-0.31.60.40.80.90.9-1.71.7-1.61.5-2.0
Locomotion velocity, session 21.21.41.91.1-1.3-1.2-1.2-1.3-0.51.31.41.30.9-1.11.3-1.31.2-1.0
Locomotion distance, session 20.40.51.50.2-0.1-0.3-0.4-0.60.40.30.80.11.0-1.21.1-1.00.7-1.2
Locomotion velocity, session 30.40.51.4-0.40.20.30.10.01.00.30.50.9-0.1-0.81.0-1.01.2-1.2
Locomotion distance, session 31.11.34.2-0.80.30.60.40.11.70.30.70.51.0-1.41.7-1.71.4-2.0
Stereotopy head waving bouts, day 31.41.73.71.9-1.8-1.8-1.9-1.5-1.91.51.01.2-0.5-0.10.1-0.20.40.5
Stereotopy head waving duration, day 31.01.22.81.5-1.3-1.5-1.7-1.3-1.41.30.91.2-0.6-0.50.3-0.30.70.1
Locomotion velocity, session 70.60.62.6-0.10.20.10.1-0.50.30.10.9-0.41.6-1.11.2-1.0-0.0-1.3
Locomotion distance, session 70.81.14.00.10.1-0.2-0.1-0.90.30.11.20.12.0-1.71.4-1.30.7-1.6
Stereotopy head waving bouts, day 70.20.31.1-0.1-0.00.0-0.20.10.50.4-0.10.9-1.0-0.30.3-0.31.1-0.4
Stereotopy head waving duration, day 70.20.21.5-0.30.10.20.00.40.50.3-0.30.6-1.20.2-0.0-0.00.6-0.1
Locomotion velocity, session 85.26.310.23.1-3.1-3.2-3.0-3.1-2.52.72.92.32.2-1.91.8-1.91.7-1.0
Locomotion distance, session 82.84.19.81.6-1.9-1.6-1.5-2.2-0.61.62.51.13.1-2.32.6-2.51.5-2.1
Degree of sensitization distance1.11.25.41.6-1.0-1.4-1.0-1.3-2.30.20.50.10.70.3-0.70.8-0.81.2
Degree of sensitization stereotypy0.50.62.3-0.90.60.80.60.61.50.1-0.20.6-0.3-0.50.6-0.71.2-1.1
Conditioned locomotion0.91.03.10.9-0.7-0.6-0.4-0.1-1.7-0.5-0.4-0.9-0.31.4-1.11.1-1.41.7
Cocaine response after cond. corrected0.30.41.5-0.50.20.50.70.60.0-0.6-0.6-0.90.50.9-0.40.4-1.20.5
Cocaine response after cond. not corrected0.10.10.50.5-0.7-0.4-0.4-0.2-0.60.50.10.40.10.3-0.10.0-0.30.4
Cocaine response before conditioning2.02.46.01.8-1.7-1.7-2.1-1.7-1.42.01.42.4-1.0-1.00.4-0.61.7-0.1
Saline control response3.54.913.5-1.62.01.71.52.30.6-2.1-2.7-1.4-3.72.5-2.72.7-1.72.3
Bone: connectivity density0.10.21.90.2-0.1-0.30.1-0.3-0.50.20.3-0.51.4-0.10.0-0.0-0.70.0
Bone: cortical apparent density1.32.13.4-1.71.61.81.61.81.5-1.6-1.6-1.2-1.81.2-0.90.9-1.00.6
Bone: cortical area0.00.00.40.00.1-0.0-0.1-0.10.10.30.00.6-0.2-0.2-0.20.10.2-0.0
Bone: cortical porosity0.60.62.40.30.0-0.4-0.7-0.60.20.40.61.1-0.3-1.20.7-0.71.6-1.0
Bone: cortical porosity0.90.91.91.0-0.5-1.0-1.3-1.2-0.60.90.91.3-0.2-1.30.7-0.71.4-0.9
Bone: cortical thickness2.23.69.3-2.92.82.82.62.33.0-1.7-1.7-0.9-1.10.4-0.60.6-0.3-0.5
Bone: cortical thickness3.94.87.7-2.62.82.72.72.62.0-2.5-2.4-2.0-1.81.8-1.71.7-1.71.1
Bone: cortical tissue density1.01.63.3-1.51.41.51.31.61.2-1.4-1.4-1.1-1.81.1-0.80.8-0.90.6
Condit. Reinf. active minus inactive responses0.10.10.30.40.1-0.5-0.5-0.5-0.5-0.00.30.3-0.2-0.5-0.10.10.3-0.1
Condit. Reinf. active-inactive response ratio0.60.72.0-0.40.70.50.40.7-0.0-0.9-1.0-0.5-1.40.9-1.11.1-0.61.0
Condit. Reinf. active responses0.10.10.30.00.50.10.10.0-0.3-0.5-0.3-0.4-0.30.1-0.60.6-0.40.5
Condit. Reinf. inactive responses0.40.51.1-0.81.00.91.00.50.5-1.0-0.5-1.00.80.1-0.30.3-0.7-0.0
Incentive salience index mean0.60.81.41.0-0.8-1.1-1.0-1.2-0.90.81.10.61.2-1.00.6-0.60.5-0.5
Condit. Reinf. lever presses1.21.75.71.4-1.4-1.4-1.1-1.6-1.11.51.60.62.4-1.21.0-1.00.4-0.7
Condit. Reinf. active minus inactive responses0.60.91.81.2-0.8-1.1-1.3-1.2-0.80.71.01.3-0.2-0.90.4-0.41.2-0.2
Condit. Reinf. active-inactive response ratio0.50.71.61.1-0.9-1.0-1.3-1.0-0.90.80.91.2-0.4-0.60.3-0.30.9-0.1
Condit. Reinf. active responses0.50.71.31.0-0.7-0.9-1.1-1.2-0.70.51.01.00.0-0.90.4-0.41.0-0.3
Condit. Reinf. inactive responses0.00.00.10.10.2-0.0-0.0-0.1-0.1-0.4-0.0-0.2-0.20.1-0.30.3-0.10.3
Condit. Reinf. lever presses0.40.62.30.4-0.2-0.4-0.7-0.70.30.40.71.10.3-1.40.7-0.71.5-0.9
Condit. Reinf. lever reinforcers received0.60.81.71.0-0.6-0.9-1.1-1.2-0.40.71.11.30.1-1.20.6-0.61.3-0.6
Conditioned reinforcement - actives0.00.11.00.10.1-0.00.0-0.1-0.50.10.0-1.0-0.3-0.20.1-0.1-0.6-0.1
Conditioned reinforcement - inactives0.10.10.5-0.10.30.1-0.1-0.10.20.00.10.2-0.7-0.60.3-0.40.6-0.6
Conditioned locomotion0.30.52.60.9-0.4-0.8-0.8-0.6-1.6-0.10.3-0.9-0.2-0.0-0.10.1-0.80.3
Patch foraging indifference point 0 sec1.13.29.2-1.61.71.91.51.91.0-1.5-2.2-1.3-3.01.6-2.01.9-1.31.5
Patch foraging indifference point AUC0.92.16.11.5-1.7-1.5-1.7-1.5-0.81.81.42.50.0-1.21.0-1.11.6-0.6
Delay disc. indifference point, 0s delay0.10.10.20.4-0.4-0.4-0.4-0.4-0.40.20.5-0.30.3-0.30.4-0.4-0.1-0.3
Delay disc. indifference point, 16s delay0.10.10.4-0.30.60.30.20.00.1-0.6-0.4-0.6-0.6-0.20.2-0.20.1-0.2
Delay disc. indifference point, 2s delay0.40.50.90.9-0.8-0.8-1.0-0.8-0.90.80.90.4-0.1-0.60.6-0.70.2-0.4
Delay disc. indifference point, 24s delay0.30.52.0-0.21.00.30.10.1-0.6-1.1-0.7-1.0-1.40.2-0.50.5-0.30.4
Delay disc. indifference point, 4s delay0.20.20.60.6-0.5-0.5-0.6-0.3-0.80.10.1-0.2-0.60.3-0.10.1-0.30.4
Delay disc. indifference point, 8s delay0.10.21.20.5-0.1-0.4-0.3-0.4-1.1-0.3-0.1-0.7-0.30.2-0.20.3-0.40.4
Indifference point function ln k0.10.31.00.1-0.3-0.1-0.1-0.50.30.50.60.31.0-0.80.8-0.80.7-0.9
Indifference point function log k0.10.31.00.1-0.3-0.1-0.1-0.50.30.50.60.31.0-0.80.8-0.80.7-0.9
Patch foraging total patch changes 0 sec1.23.59.6-1.82.02.11.72.11.2-1.6-2.3-1.3-3.11.6-2.01.9-1.21.4
Patch foraging total patch changes 12 sec0.40.62.7-0.90.60.90.60.91.1-0.2-0.80.3-1.60.4-0.50.40.20.2
Patch foraging total patch changes 18 sec1.43.35.6-2.01.92.11.92.21.5-1.8-2.2-1.4-2.41.7-1.71.6-1.51.3
Patch foraging total patch changes 24 sec0.82.74.6-2.12.12.11.82.01.9-1.9-1.8-1.3-1.90.9-1.00.9-0.80.4
Patch foraging total patch changes 6 sec1.62.66.1-1.91.92.01.62.01.6-1.8-2.0-1.1-2.51.2-1.11.0-0.70.6
Patch foraging time to switch 0 sec1.24.79.5-2.02.12.02.32.20.8-2.6-2.3-3.1-0.72.5-2.02.1-2.61.8
Patch foraging water rate 0 sec0.00.20.50.2-0.4-0.1-0.5-0.2-0.00.70.20.6-0.7-0.60.3-0.40.5-0.4
Patch foraging water rate 12 sec0.20.72.8-1.10.81.10.80.71.7-0.5-0.2-0.1-0.3-0.50.8-0.80.5-1.1
Patch foraging water rate 18 sec0.20.41.7-0.40.40.60.40.6-0.0-0.3-0.7-0.4-1.30.5-0.70.6-0.70.5
Patch foraging water rate 24 sec0.40.52.0-0.90.30.90.60.61.40.0-0.00.0-0.3-0.40.9-0.90.5-1.0
Patch foraging water rate 6 sec0.20.20.8-0.30.10.30.10.10.90.00.10.4-0.4-0.50.6-0.60.6-0.7
Seeking ratio, delayed vs. immediate footshock0.10.20.80.2-0.5-0.2-0.20.10.20.40.00.9-0.90.5-0.10.10.30.3
Distance traveled before self-admin0.10.20.60.4-0.8-0.4-0.3-0.1-0.30.70.30.50.50.4-0.00.0-0.20.2
Distance traveled after self-admin0.40.61.40.9-1.2-0.8-0.8-0.3-0.91.00.10.8-1.00.9-0.70.7-0.31.0
Extensor digitorum longus weight1.04.07.62.6-2.8-2.7-2.7-2.5-2.02.42.11.51.0-1.41.4-1.41.2-0.7
Bone: elastic displacement0.30.30.9-0.60.90.50.20.30.9-0.3-0.20.1-0.7-0.70.4-0.40.7-0.9
Bone: elastic work0.20.30.9-0.61.00.50.40.50.4-0.7-0.6-0.4-0.80.1-0.30.3-0.2-0.1
Bone: endosteal estimation2.56.121.03.7-3.3-3.4-3.3-2.4-4.62.11.21.5-0.60.8-1.21.1-0.62.5
Bone: endosteal perimeter1.43.410.22.8-2.8-2.6-2.4-2.0-3.21.81.31.20.90.3-0.20.2-0.21.4
Epididymis fat weight8.341.970.2-8.38.28.48.18.06.4-7.5-7.2-6.4-4.24.9-4.14.2-4.62.1
Delta time in closed arm before/after self-admin0.90.91.8-0.91.30.90.91.00.2-1.4-1.0-1.3-0.60.8-0.60.6-1.00.4
Delta time in open arm before/after self-admin0.20.21.10.5-0.9-0.5-0.5-0.3-0.31.00.50.60.1-0.20.2-0.20.1-0.2
Diff in mean of infusions in LGA sessions0.30.53.2-0.70.50.61.00.50.5-0.7-0.2-0.91.80.30.3-0.1-0.5-0.2
Delay discount exponential model param0.10.10.5-0.40.10.30.40.40.70.1-0.20.60.40.1-0.30.20.20.1
Extinction: sum of active levers before priming0.10.21.1-0.50.40.40.50.30.6-0.2-0.0-0.11.1-0.20.2-0.10.1-0.2
Active lever presses in extinction session 60.90.92.1-0.81.40.80.90.8-0.2-1.3-1.2-1.4-0.20.7-1.01.1-0.90.7
Bone: final force2.74.46.8-1.31.71.61.52.00.1-2.2-2.5-2.1-2.42.6-2.62.6-2.42.4
Bone: final moment1.93.14.8-1.11.41.31.31.60.0-1.8-2.1-1.7-2.12.2-2.22.2-2.02.0
Food consumed during 24 hour testing period0.71.44.70.5-0.3-0.4-0.10.3-1.5-0.6-0.9-1.0-0.71.8-1.61.6-1.72.2
Glucose4.16.510.33.2-3.1-3.2-3.2-3.2-2.52.92.72.32.2-2.21.6-1.71.8-1.0
Heart weight0.60.92.80.7-0.3-0.7-1.3-1.0-0.30.90.61.3-1.7-1.40.3-0.41.4-0.6
Delay discount hyperbolic model param0.10.20.4-0.50.30.50.50.50.7-0.1-0.40.20.30.3-0.50.4-0.10.3
Intermittent access intake day 1-15 change0.10.41.2-0.50.30.50.80.70.2-0.4-0.6-0.2-0.21.1-0.80.8-0.70.7
Intermittent access intake escalation0.20.91.9-0.80.70.91.11.10.3-0.9-1.0-0.6-0.81.4-1.11.1-0.90.9
Intermittent access intake escalation 20.20.41.00.9-1.0-0.8-0.6-0.6-1.00.80.60.50.20.1-0.10.1-0.10.2
Intermitt. access day 1 inactive lever presses0.11.22.90.4-1.2-0.5-0.5-0.70.91.51.11.70.9-0.91.2-1.21.4-1.3
Intermitt. access day 15 inactive lever presses0.10.51.11.0-1.0-0.8-0.8-0.6-0.70.70.20.7-0.70.3-0.50.50.00.7
Intermitt. access escalation Index0.20.73.3-0.6-0.20.40.60.21.50.60.50.41.8-0.51.0-1.00.5-1.1
Intermittent access day 1 total infusions0.20.52.10.30.1-0.4-0.4-0.7-0.40.50.6-0.50.4-1.50.8-0.90.5-1.1
Intermittent access day 15 total infusions0.10.10.4-0.50.60.50.50.40.1-0.2-0.3-0.4-0.5-0.1-0.10.1-0.2-0.2
Intermittent access terminal intake (last 3 days)0.10.10.5-0.40.60.40.30.20.1-0.2-0.2-0.3-0.7-0.3-0.0-0.00.1-0.3
Intermittent access total infusions0.10.10.50.10.2-0.0-0.2-0.2-0.30.30.1-0.2-0.4-0.70.2-0.30.2-0.5
Intermittent access day 1 locomotion0.10.10.20.4-0.3-0.4-0.4-0.4-0.50.30.3-0.4-0.3-0.40.1-0.1-0.2-0.1
Intermittent access day 15 total locomotion0.31.12.80.8-0.3-0.6-0.5-0.1-1.7-0.5-0.5-0.9-1.41.2-1.21.2-1.31.6
Intermittent access total locomotion0.40.52.11.0-0.6-0.8-0.9-0.5-1.50.20.1-0.4-1.00.3-0.60.5-0.70.8
Intermittent access standard deviation0.41.94.3-0.80.91.11.01.30.1-1.0-1.6-0.8-2.11.8-1.91.8-1.11.6
Left kidney weight0.43.310.90.8-0.3-0.4-0.50.3-1.9-0.4-1.4-0.7-3.32.1-2.72.6-1.73.0
Right kidney weight0.64.313.01.4-0.8-1.0-0.9-0.0-2.8-0.3-1.3-0.8-3.02.5-2.92.8-2.33.6
Cocaine induced anxiety0.41.13.51.3-1.9-1.2-1.2-1.1-0.51.41.11.20.8-0.30.6-0.60.4-0.2
Post-drug Anxiety0.20.20.90.6-1.0-0.4-0.5-0.4-0.30.40.30.6-0.00.3-0.20.1-0.00.5
Baseline Anxiety1.62.65.0-2.02.22.02.11.81.0-2.2-1.7-1.9-0.71.2-1.11.1-1.20.7
Tail length1.89.821.24.5-4.1-4.3-4.6-3.5-4.23.52.43.9-1.4-0.9-0.0-0.21.71.1
Length with tail3.214.337.35.8-4.9-5.3-5.6-4.3-6.13.82.53.1-1.9-0.3-1.00.80.62.4
Length without tail0.94.716.73.0-2.3-2.5-2.6-1.7-4.11.00.4-0.2-1.81.2-1.91.8-1.72.8
Times rat made contact with spout0.91.02.9-1.51.41.31.21.21.7-1.1-0.9-0.5-0.70.10.0-0.00.1-0.6
Lifetime Intake0.10.10.20.10.3-0.1-0.2-0.2-0.40.0-0.0-0.4-0.5-0.4-0.0-0.10.0-0.2
Liver weight, left1.62.87.82.4-2.4-2.3-2.2-1.5-2.81.80.81.2-0.40.6-0.80.7-0.51.7
Liver weight, right4.98.518.84.3-4.3-4.1-4.2-3.4-4.13.22.62.6-0.0-0.80.7-0.81.00.8
Locomotor activity0.30.52.30.4-0.9-0.3-0.6-0.40.21.10.21.5-1.4-0.00.1-0.30.8-0.0
Locomotor testing distance0.20.41.2-0.90.40.80.80.81.1-0.1-0.70.1-0.90.7-0.20.2-0.30.2
Locomotor testing rearing0.10.41.4-0.2-0.10.40.40.5-0.1-0.2-0.6-0.4-0.91.2-0.70.7-1.01.0
Locomotion in novel chamber0.10.10.4-0.30.30.20.30.10.40.20.1-0.2-0.1-0.40.2-0.20.1-0.6
Locomotion in novel chamber post-restriction0.51.52.4-0.91.10.80.91.30.0-1.4-1.3-1.2-1.21.5-1.41.5-1.51.4
Fecal boli incidents, locomotor time 10.20.42.00.10.20.10.30.2-0.8-0.6-0.4-1.40.00.6-0.60.6-1.20.7
Change in fecal boli incidents, locomotor task0.10.10.2-0.10.00.20.00.30.1-0.0-0.20.4-0.20.4-0.20.2-0.10.3
Time >=10cm from walls, locomotor time 11.21.54.8-0.2-0.20.30.61.1-0.5-0.5-1.1-1.0-0.22.2-1.81.7-2.02.0
Bouts of movement, locomotor time 10.30.41.00.6-1.0-0.7-0.4-0.4-0.00.80.51.01.0-0.10.2-0.10.4-0.0
Total resting periods, locomotor time 10.60.71.91.1-1.4-1.1-0.9-0.8-0.61.00.71.11.0-0.10.1-0.10.30.2
Rest time, locomotor task time 10.81.32.11.1-1.1-1.1-1.2-1.3-0.61.11.41.00.9-1.31.2-1.20.9-1.0
Distance moved, locomotor task time 10.41.12.2-0.80.80.80.71.10.2-0.8-1.3-0.8-1.51.3-1.31.3-0.81.3
Vertical activity count, locomotor time 10.53.26.5-0.70.90.91.01.6-0.4-1.3-2.1-1.6-2.22.5-2.52.5-2.02.5
Time >=10cm from walls, locomotor time 21.02.85.4-0.51.00.60.71.2-1.0-1.6-1.6-2.2-1.62.2-2.12.1-2.32.2
Bouts of movement, locomotor time 20.51.84.11.9-2.0-2.0-1.9-1.4-1.21.41.31.8-0.0-0.20.5-0.40.90.1
Total resting periods, locomotor time 20.72.85.62.1-2.3-2.3-2.2-1.8-1.11.91.82.40.6-0.81.0-1.01.4-0.5
Rest time, locomotor task time 21.01.73.51.3-1.9-1.4-1.2-1.2-0.51.71.61.21.8-0.91.2-1.20.7-0.8
Distance moved, locomotor task time 22.83.75.4-1.01.91.31.21.5-0.6-2.2-2.3-2.3-2.32.0-2.32.3-2.22.3
Vertical activity count, locomotor time 21.12.54.5-0.31.10.60.60.9-1.2-1.5-1.7-2.0-2.11.8-2.02.0-2.02.1
Light reinforcement 10.41.94.8-1.00.70.91.21.60.3-1.3-1.6-1.6-0.72.2-1.21.3-2.11.6
Light reinforcement 20.40.92.90.3-0.3-0.20.10.4-1.1-0.7-0.6-1.3-0.41.7-0.91.0-1.71.6
Bone: marrow area2.46.020.93.6-3.2-3.3-3.2-2.3-4.61.91.01.4-0.80.9-1.41.3-0.72.6
Bone: maximum diameter2.14.27.62.7-2.7-2.7-2.7-2.5-2.42.52.22.11.3-1.21.0-1.01.0-0.2
Bone: maximum force0.50.92.1-0.30.60.40.40.6-0.4-0.8-1.1-0.9-1.31.1-1.41.4-1.21.3
Bone: maximum moment0.20.41.20.00.30.10.00.2-0.5-0.4-0.7-0.5-1.00.7-1.11.0-0.81.0
Mean time between licks in bursts1.69.614.63.6-3.8-3.6-3.7-3.8-2.43.33.62.82.2-2.72.8-2.82.7-1.7
Mean num. licks in bursts0.71.84.1-1.62.01.51.41.51.3-1.8-1.4-1.2-1.40.7-0.91.0-0.70.3
Cd content in liver1.41.55.3-0.71.10.70.90.9-0.3-1.5-1.1-2.3-0.51.2-1.21.3-2.11.1
Co content in liver4.55.37.1-1.82.22.02.12.30.5-2.7-2.6-2.6-1.72.4-2.62.6-2.72.4
Cu content in liver2.12.56.9-2.42.32.22.21.82.6-1.7-1.3-0.9-0.00.10.1-0.0-0.0-1.0
Fe content in liver0.30.41.3-0.10.40.30.20.3-0.4-1.0-0.6-1.1-0.70.8-0.60.7-0.80.8
K content in liver1.71.72.61.2-1.2-1.2-1.2-1.5-0.41.01.51.01.6-1.61.5-1.51.3-1.2
Mg content in liver3.23.65.52.2-2.3-2.1-2.1-2.3-1.31.92.11.91.9-1.81.7-1.71.5-1.0
Mn content in liver6.77.514.23.7-3.8-3.4-3.5-3.6-2.92.82.92.32.1-1.91.9-1.91.7-0.7
Na content in liver0.30.41.4-0.60.40.50.50.31.2-0.10.10.50.3-0.40.7-0.70.8-0.8
Rb content in liver0.20.31.10.3-0.1-0.3-0.1-0.0-0.8-0.3-0.2-0.90.30.4-0.50.5-1.00.7
Se content in liver7.18.412.43.2-3.2-3.2-3.5-3.5-1.92.93.43.31.5-2.92.5-2.63.1-1.9
Sr content in liver0.20.20.80.00.30.00.00.1-0.6-0.4-0.2-0.9-0.30.3-0.50.5-0.80.5
Zn content in liver1.51.83.11.7-1.5-1.7-1.7-1.8-1.21.11.60.91.0-1.31.1-1.10.9-0.7
Bone: minimum diameter1.02.06.12.1-1.9-1.9-1.8-1.5-2.51.50.80.90.40.2-0.50.4-0.31.2
Time in familiar zone, hab. session 10.60.71.5-1.21.21.21.20.81.2-1.0-0.5-0.90.1-0.1-0.00.1-0.1-0.4
Time in novel zone, hab. session 10.30.30.70.6-0.7-0.7-0.8-0.4-0.50.80.50.8-0.4-0.10.4-0.40.3-0.1
Total zone transitions, hab. session 11.31.85.6-1.10.50.90.60.22.40.50.61.00.7-1.61.7-1.71.6-2.3
Total locomotion distance, hab. session 11.31.84.7-0.4-0.10.1-0.0-0.41.70.91.11.31.4-1.81.9-1.91.7-2.2
Locomotion velocity, hab. session 11.11.63.9-0.1-0.2-0.1-0.2-0.71.30.91.11.31.3-1.81.7-1.71.8-2.0
Time in familiar zone, hab. session 20.10.10.3-0.1-0.20.10.10.10.50.10.10.4-0.20.00.4-0.40.5-0.2
Time in novel zone, hab. session 20.30.30.90.10.4-0.1-0.10.2-0.8-0.3-0.5-0.6-0.60.5-0.90.9-1.00.7
Total zone transitions, hab. session 20.50.72.5-0.70.10.60.40.31.60.30.30.60.3-0.71.2-1.20.8-1.3
Total locomotion distance, hab. session 21.21.64.4-0.7-0.20.40.3-0.11.90.70.80.81.4-1.32.1-2.01.3-2.1
Locomotion velocity, hab. session 21.72.25.9-0.5-0.40.20.1-0.41.90.91.21.11.7-1.72.4-2.41.7-2.4
Novel to familiar place preference ratio0.20.30.8-0.70.90.60.60.50.5-0.8-0.5-0.7-0.20.1-0.10.1-0.2-0.3
Novelty place preference0.10.10.5-0.50.70.40.40.40.4-0.5-0.3-0.4-0.3-0.00.0-0.0-0.0-0.4
Time in novel zone, NPP test0.10.10.3-0.30.60.30.20.30.2-0.5-0.3-0.3-0.3-0.00.0-0.0-0.0-0.3
Total zone transitions, NPP test1.21.74.6-0.0-0.3-0.2-0.3-0.71.10.81.21.01.7-1.82.0-1.91.5-2.1
Total locomotion distance, NPP test0.50.72.0-0.60.40.50.40.01.2-0.10.5-0.31.4-1.01.2-1.10.3-1.4
Locomotion velocity, NPP test0.81.13.0-0.90.50.70.70.21.7-0.20.4-0.31.7-1.11.4-1.30.5-1.7
Intraocular pressure0.10.20.60.3-0.2-0.2-0.1-0.1-0.6-0.3-0.3-0.7-0.00.4-0.60.6-0.80.7
Delta distance traveled before/after self-admin0.40.52.90.5-0.2-0.4-0.6-0.1-0.80.2-0.40.2-1.70.4-0.80.8-0.10.8
Delta ambulatory time before/after self-admin0.30.42.10.6-0.5-0.5-0.6-0.1-0.90.3-0.20.3-1.40.5-0.80.7-0.20.9
Parametrial fat weight1.84.29.4-1.10.81.31.52.0-0.2-1.5-2.3-2.1-2.03.1-2.42.4-2.82.8
Pavlov. Cond. lever latency4.55.79.6-1.81.81.91.92.50.6-2.5-2.8-2.2-3.03.1-2.62.6-2.62.7
Pavlov. Cond. magazine entry latency4.55.89.62.3-2.3-2.4-2.4-2.7-1.12.82.73.12.0-2.62.1-2.22.6-1.9
Pavlov. Cond. change in total contacts1.11.22.71.1-1.0-1.1-1.2-1.3-0.61.41.11.60.6-1.30.7-0.81.4-0.7
Pavlov. Cond. index score4.86.19.02.2-2.2-2.3-2.3-2.8-1.02.82.92.72.7-3.02.4-2.42.7-2.3
Pavlov. Cond. latency score4.76.08.42.2-2.2-2.3-2.2-2.8-1.12.72.92.62.7-2.92.4-2.42.6-2.2
Pavlov. Cond. lever contacts3.34.07.31.5-1.6-1.7-1.6-2.2-0.72.12.41.72.7-2.52.1-2.11.9-2.1
Pavlov. Cond. magazine entry number3.34.27.4-1.71.81.81.92.20.6-2.4-2.3-2.7-1.82.5-1.92.0-2.51.9
Pavlov. Cond. intertrial magazine entries2.12.64.9-1.52.11.61.41.50.7-2.2-1.7-2.0-1.61.3-1.41.5-1.81.1
Pavlov. Cond. lever-magazine prob. diff.4.55.69.01.9-2.0-2.1-2.1-2.6-0.82.62.82.52.7-3.02.4-2.42.6-2.4
Pavlov. Cond. response bias5.16.49.12.2-2.3-2.3-2.4-2.8-0.92.93.02.92.4-3.02.5-2.62.7-2.4
Pavlov. Cond. lever latency0.20.31.20.0-0.4-0.00.30.3-0.60.1-0.3-0.50.31.0-0.40.3-1.10.8
Pavlov. Cond. magazine entry latency0.40.62.71.2-0.8-1.2-0.9-0.9-1.60.40.50.10.50.0-0.40.4-0.20.7
Pavlov. Cond. change in total contacts0.00.10.50.20.3-0.2-0.3-0.3-0.0-0.20.10.5-0.4-0.5-0.20.20.7-0.0
Pavlov. Cond. index score0.20.30.70.8-0.3-0.8-0.8-0.8-0.70.30.60.50.1-0.70.1-0.00.7-0.1
Pavlov. Cond. latency score0.20.30.60.8-0.3-0.8-0.8-0.7-0.70.30.50.40.1-0.60.1-0.00.6-0.0
Pavlov. Cond. lever contacts0.10.20.6-0.20.60.2-0.0-0.00.6-0.30.10.3-0.4-0.70.1-0.10.8-0.5
Pavlov. Cond. magazine entry number0.20.20.6-0.3-0.00.30.10.00.80.30.20.5-0.1-0.40.7-0.70.6-0.8
Pavlov. Cond. intertrial magazine entries1.12.44.11.7-2.0-1.6-1.5-1.8-1.01.71.71.91.5-1.11.4-1.51.5-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.20.50.7-0.2-0.7-0.7-0.6-0.60.20.50.30.1-0.5-0.10.10.50.0
Pavlov. Cond. response bias0.20.30.90.6-0.0-0.6-0.7-0.8-0.30.20.70.70.1-1.00.2-0.20.8-0.4
Time in closed arm before self-admin0.00.00.10.3-0.3-0.2-0.2-0.3-0.30.10.2-0.10.0-0.10.1-0.1-0.1-0.1
Time in closed arm after self-admin0.40.51.7-1.01.30.90.80.60.7-1.0-0.4-0.9-0.2-0.20.3-0.2-0.3-0.7
Time in open arm before self-admin0.30.41.30.2-0.0-0.3-0.4-0.50.10.50.61.00.3-0.80.6-0.61.1-0.8
Time in open arm after self-admin0.91.02.31.1-1.4-1.0-1.0-1.0-0.71.51.01.30.4-0.70.7-0.70.9-0.4
Bone: periosteal estimation1.02.47.52.3-2.0-2.1-2.1-1.5-2.71.40.71.3-0.70.4-0.80.7-0.21.5
Bone: periosteal perimeter0.40.82.11.3-1.3-1.2-1.2-0.8-1.51.00.41.0-0.00.2-0.40.30.10.9
Bone: post-yield work1.11.86.12.0-1.7-1.9-1.7-1.7-2.51.40.90.40.6-0.1-0.50.5-0.51.0
Progressive ratio test 1 active lever presses0.10.10.6-0.30.70.20.20.2-0.2-0.4-0.3-0.8-0.3-0.2-0.20.1-0.3-0.0
Progressive ratio test 1 breakpoint0.00.10.4-0.20.60.20.10.1-0.2-0.3-0.2-0.6-0.3-0.3-0.10.0-0.2-0.1
Progressive ratio test 1 inactive lever presses0.51.42.3-1.41.51.51.51.40.9-1.2-1.3-1.4-0.50.9-0.80.8-1.10.6
Progressive ratio test 2 active lever presses0.10.10.4-0.50.60.40.50.30.3-0.2-0.0-0.40.3-0.30.3-0.30.0-0.5
Progressive ratio test 2 breakpoint0.10.20.4-0.60.70.40.50.30.4-0.2-0.1-0.40.3-0.30.3-0.30.0-0.5
Progressive ratio test 2 inactive lever presses0.20.61.00.8-0.6-0.8-0.9-0.9-0.70.71.00.60.5-0.90.8-0.80.5-0.7
Incentive Sensitization - Responses0.20.51.2-0.3-0.20.10.2-0.10.80.80.60.60.9-0.90.8-0.80.8-1.1
Incentive Sensitization - Breakpoint0.20.30.9-0.4-0.00.20.40.00.90.70.50.40.9-0.70.7-0.60.6-0.9
Sum of active levers in priming session hrs 5-60.10.00.20.1-0.1-0.1-0.1-0.2-0.20.30.10.20.2-0.40.2-0.20.4-0.2
Progressive ratio0.92.56.1-0.91.11.31.11.50.2-1.4-1.8-0.9-2.52.2-2.02.0-1.32.0
Food seeking constrained by brief footshock0.50.71.7-0.81.30.70.80.80.1-1.0-1.0-0.9-0.70.5-0.90.9-0.50.6
Seeking ratio, punishment vs. effort0.51.13.00.2-0.1-0.6-0.5-0.80.30.71.00.61.5-1.71.4-1.41.2-1.7
Retroperitoneal fat weight0.10.61.4-0.20.30.30.40.6-0.3-0.8-0.8-0.9-0.21.1-0.90.9-1.21.1
Reaction time number correct0.93.14.8-2.12.12.22.12.11.4-2.2-2.0-1.8-1.61.7-1.31.3-1.30.8
Reaction time mean minus median1.06.112.63.6-3.5-3.5-3.2-3.0-3.22.72.52.01.8-1.20.8-0.91.00.2
Reaction time mean minus median AUC0.75.011.13.3-3.0-3.2-2.9-2.9-3.32.12.31.11.8-1.20.7-0.70.60.2
Reaction time num false alarms0.91.52.91.4-1.7-1.3-1.3-1.4-0.71.71.21.60.7-0.90.8-0.91.2-0.5
Reaction time num false alarms AUC0.92.14.91.4-1.8-1.4-1.5-1.5-0.52.01.42.20.7-1.31.1-1.21.7-0.8
Reaction time trials correct on left0.93.14.8-2.12.12.22.12.11.4-2.2-2.0-1.8-1.61.7-1.31.3-1.30.8
Reaction time trials on left0.93.04.4-2.02.02.12.12.01.3-2.1-1.9-1.7-1.51.7-1.31.4-1.30.9
Reaction time mean1.43.08.72.7-2.4-2.5-2.2-2.1-2.91.71.50.61.4-0.4-0.0-0.0-0.20.8
Reaction time mean AUC1.22.89.12.6-2.2-2.4-2.0-2.0-3.01.51.30.41.3-0.2-0.20.2-0.41.0
Median of all reaction times0.91.45.11.7-1.5-1.6-1.3-1.3-2.30.90.8-0.11.00.1-0.40.4-0.71.0
Reaction time omissions1.22.05.32.0-2.3-1.9-1.5-1.6-1.81.91.31.11.6-0.30.5-0.50.30.3
Reaction time false alarm rate3.85.39.12.4-2.7-2.4-2.5-2.6-1.13.02.53.01.5-2.21.8-1.92.4-1.4
Reaction time premature initiation rate0.00.10.2-0.30.20.10.20.30.30.1-0.3-0.2-0.40.2-0.30.2-0.20.2
Reaction time premature initiations0.61.72.3-1.41.41.41.41.50.9-1.3-1.5-1.4-1.41.3-1.21.2-1.20.9
Std. dev. reaction times2.16.914.63.8-3.6-3.7-3.4-3.3-3.63.02.52.21.8-1.30.6-0.71.10.4
Reaction time trials completed0.93.04.4-2.02.02.12.12.01.3-2.1-1.9-1.7-1.51.7-1.31.4-1.30.9
Reaction time trials AUC0.93.14.6-2.02.02.12.12.01.3-2.1-1.9-1.8-1.51.7-1.31.4-1.40.9
Run reversals in cocaine runway, females0.40.51.2-0.51.00.50.40.5-0.1-0.9-0.8-1.1-1.00.2-0.70.7-0.60.4
Run reversals in cocaine runway, males3.03.35.92.4-2.4-2.4-2.3-2.2-1.92.41.91.71.2-1.31.0-1.11.0-0.5
Latency to leave start box in cocaine runway0.20.31.2-0.50.30.50.40.10.8-0.00.20.31.1-0.50.5-0.60.5-0.8
Latency to leave start box in cocaine runway, F0.10.20.5-0.40.30.40.40.10.6-0.30.1-0.10.7-0.40.5-0.50.2-0.6
Latency to leave start box in cocaine runway, M0.10.10.3-0.40.30.40.30.20.50.2-0.10.50.6-0.20.1-0.10.4-0.3
Std. dev. time between licks in bursts4.07.610.92.9-3.3-3.0-3.1-3.2-1.83.03.32.52.1-2.52.8-2.82.5-1.8
Total sessions with >9 infusions0.10.10.40.30.0-0.3-0.4-0.3-0.40.20.10.0-0.7-0.40.0-0.10.2-0.2
Short access day 1 total inactive lever presses0.71.43.11.6-1.3-1.6-1.8-1.4-1.61.31.21.0-0.0-0.80.6-0.70.6-0.2
Short access day 10 total inactive lever presses0.10.52.3-0.3-0.60.20.40.21.40.90.31.50.90.10.4-0.40.8-0.4
Short access day 1 total infusions0.20.40.80.7-0.4-0.8-0.9-0.8-0.70.70.50.3-0.1-0.90.4-0.40.6-0.4
Short access day 10 total infusions0.00.00.2-0.10.20.00.00.1-0.1-0.1-0.2-0.4-0.4-0.0-0.20.1-0.10.1
Short access total infusions0.00.10.30.10.3-0.1-0.2-0.1-0.5-0.1-0.1-0.5-0.4-0.3-0.10.0-0.1-0.0
Short access day 1 locomotion0.20.30.60.1-0.4-0.2-0.2-0.30.50.70.40.70.8-0.60.5-0.50.8-0.6
Short access day 10 total locomotion0.20.82.21.1-1.5-1.1-1.3-0.7-0.41.40.81.5-0.4-0.20.1-0.10.60.1
Short access total locomotion0.10.20.60.7-0.7-0.7-0.7-0.4-0.50.50.30.4-0.1-0.0-0.00.00.00.2
One hour access (0.3 mA shock)1.21.53.8-0.0-0.6-0.2-0.1-0.60.91.31.20.91.6-1.61.7-1.71.3-1.9
Compulsive drug intake0.81.35.50.7-1.4-0.9-0.5-0.90.21.51.20.92.3-0.81.2-1.10.6-1.0
One hour access (shock baseline)0.10.10.50.20.1-0.2-0.3-0.3-0.30.20.30.1-0.5-0.70.4-0.40.4-0.6
Social response proportion0.20.20.60.8-0.6-0.7-0.8-0.6-0.70.50.30.4-0.2-0.1-0.10.00.10.2
Social responses0.10.20.50.5-0.6-0.5-0.6-0.3-0.20.50.30.7-0.4-0.00.2-0.20.40.0
Social time2.64.19.22.2-3.0-2.3-1.9-2.2-1.32.82.12.42.4-1.11.6-1.61.3-0.8
Soleus weight5.416.130.55.5-5.4-5.4-5.5-4.9-4.64.74.23.71.6-2.32.2-2.32.2-0.7
Bone: stiffness0.61.12.0-0.60.80.70.80.90.0-1.1-1.2-1.0-0.91.3-1.41.4-1.41.4
Tibialis anterior weight0.00.10.4-0.20.00.10.00.10.6-0.0-0.1-0.1-0.2-0.20.5-0.50.3-0.5
Time to tail flick, vehicle, before self-admin0.20.21.10.3-1.0-0.10.1-0.10.00.30.30.30.90.60.2-0.2-0.30.4
Time to tail flick, vehicle, after self-admin0.10.10.50.3-0.5-0.4-0.3-0.2-0.20.70.40.50.5-0.20.1-0.10.1-0.2
Time to tail flick, test, before self-admin0.40.42.3-0.70.30.60.60.41.50.10.10.60.2-0.30.6-0.60.7-0.9
Time to tail flick, test, after self-admin0.90.91.60.6-0.8-0.8-0.7-0.9-0.11.01.11.31.2-1.01.1-1.01.2-0.9
Delta time to tail flick, vehicle, before/after SA0.30.42.0-0.81.40.60.60.50.4-0.7-0.6-0.7-0.1-0.4-0.30.3-0.1-0.4
Delta time to tail flick, test, before/after SA0.10.10.3-0.00.20.00.20.1-0.4-0.3-0.3-0.50.40.3-0.20.2-0.40.4
Tibia length1.13.210.22.6-2.3-2.3-2.1-1.7-3.21.50.71.4-0.60.9-1.21.1-0.62.1
Ambulatory time before self-admin0.00.10.30.1-0.4-0.1-0.0-0.10.10.50.30.50.60.10.2-0.10.2-0.2
Ambulatory time after self-admin0.30.40.90.7-1.0-0.6-0.6-0.2-0.80.80.10.7-0.80.6-0.50.5-0.10.7
Bone: tissue strength0.50.61.4-0.70.70.70.80.90.2-0.7-0.9-1.2-0.50.7-0.70.7-1.00.4
Total heroin consumption0.10.10.60.1-0.5-0.20.00.00.20.70.10.80.60.20.00.10.40.2
Bone: trabecular number0.20.41.9-0.70.70.50.80.30.6-0.4-0.1-0.81.4-0.20.3-0.2-0.5-0.5
Bone: trabecular spacing0.50.73.40.5-0.3-0.4-0.60.1-1.0-0.1-0.50.2-1.81.0-1.11.0-0.31.3
Bone: trabecular thickness0.20.31.30.10.2-0.00.3-0.1-0.6-0.4-0.1-1.00.70.4-0.50.5-1.20.5
Bone: trabecular tissue density0.50.91.91.1-0.8-1.0-1.2-1.1-0.71.00.81.4-0.4-0.90.4-0.41.3-0.4
Water consumed over 24 hours0.00.10.4-0.0-0.4-0.1-0.20.00.20.70.10.40.1-0.10.4-0.40.2-0.3
Number of responses in last shaping day1.62.14.21.1-0.8-1.2-1.7-1.5-0.61.31.51.50.2-2.11.6-1.72.0-1.7