Hub : Genes

Slc29a1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XM_006244561.3 0.04 0.02 4.4e-03 0.01 0.02 0.01 0.01 6.2e-02 2.7e-03 2.9e-02 2.0e-02
2 Liver alternative TSS XM_006244561.3 0.04 0.02 4.7e-03 0.01 0.02 0.01 0.01 6.9e-02 3.8e-03 3.3e-02 2.4e-02
3 Brain gene expression Slc29a1 0.04 0.03 4.7e-03 0.01 0.01 0.01 0.01 7.5e-02 4.9e-02 2.8e-02 2.7e-02
4 IL gene expression Slc29a1 0.16 0.08 2.2e-03 0.12 0.12 0.11 0.11 7.8e-04 9.7e-04 1.5e-03 1.3e-03
5 Brain alternative TSS XM_006244561.3 0.04 0.02 2.7e-03 0.03 0.03 0.03 0.03 3.4e-04 5.3e-04 1.8e-03 9.5e-04
6 Brain alternative TSS XM_006244561.3 0.04 0.02 2.1e-03 0.04 0.03 0.03 0.03 2.7e-04 5.9e-04 1.8e-03 1.5e-03
7 Adipose gene expression Slc29a1 0.18 0.08 8.1e-15 0.13 0.12 0.12 0.13 7.6e-14 1.6e-13 1.5e-13 5.4e-14
8 Liver gene expression Slc29a1 0.07 0.03 6.9e-08 0.06 0.06 0.04 0.05 1.5e-07 4.6e-07 7.9e-06 1.2e-06
9 Liver isoform ratio XM_039084162.1 0.05 0.03 1.2e-04 0.04 0.01 0.03 0.03 2.2e-05 1.2e-02 4.2e-04 2.4e-04
10 Liver intron excision ratio chr9_15403262_15405034 0.12 0.05 2.9e-15 0.14 0.13 0.11 0.14 1.2e-15 3.4e-14 2.7e-12 3.7e-15
11 Liver alternative TSS NM_031684.2 0.13 0.06 1.0e-15 0.14 0.13 0.13 0.13 8.6e-15 6.9e-14 3.6e-14 2.0e-14
12 Liver alternative TSS XM_039084162.1 0.08 0.04 7.4e-10 0.08 0.07 0.07 0.07 7.5e-09 2.8e-08 5.1e-08 4.3e-08
13 NAcc gene expression Slc29a1 0.1 0.04 1.7e-12 0.09 0.1 0.1 0.11 6.8e-11 1.9e-11 1.3e-11 8.9e-13
14 Liver intron excision ratio chr9_15399733_15405034 0.19 0.07 0.0e+00 0.19 0.19 0.19 0.2 1.0e-20 1.4e-20 2.8e-20 3.1e-21
15 Liver isoform ratio NM_031684.2 0.18 0.08 0.0e+00 0.17 0.16 0.17 0.18 1.4e-18 1.4e-17 1.1e-18 2.9e-19
16 pVTA isoform ratio XM_039084163.1 0.09 0.05 2.0e-03 0.02 0.03 0.03 0.03 5.6e-02 1.8e-02 1.3e-02 2.8e-02
17 Liver isoform ratio XM_006244560.3 0.04 0.02 1.3e-04 0.03 0.03 0.03 0.04 1.0e-04 3.9e-04 3.2e-04 5.7e-05
18 PL gene expression Slc29a1 0.06 0.03 2.4e-06 0.02 0.06 0.05 0.04 3.2e-03 7.0e-07 7.6e-06 4.4e-05
19 Brain intron excision ratio chr9_15403262_15405034 0.09 0.06 1.1e-03 0.01 0.03 0.01 0.01 6.5e-02 1.9e-03 1.3e-02 2.6e-02
20 OFC gene expression Slc29a1 0.2 0.1 1.5e-03 0.1 0.12 0.08 0.08 1.9e-03 7.3e-04 6.5e-03 5.3e-03
21 BLA gene expression Slc29a1 0.11 0.08 6.9e-04 0.01 0.06 0.03 0.03 9.3e-02 2.2e-04 8.6e-03 1.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.50.91.9-1.0-1.00.2-0.21.01.21.10.70.70.7-1.21.2-0.71.01.0-0.1-0.8-0.6-1.2-1.2-1.4
Area under the delay curve2.42.68.7-0.5-0.4-2.93.02.11.31.31.31.31.3-1.11.1-2.21.21.2-1.5-1.6-2.3-0.4-1.6-0.8
BMI with tail3.611.717.03.73.70.5-0.5-4.1-4.0-3.9-3.7-3.7-3.74.1-4.13.2-4.0-4.00.54.02.22.83.53.1
BMI without tail11.724.235.85.35.31.3-1.1-5.3-5.8-5.8-5.5-5.5-5.56.0-6.04.8-5.9-5.91.25.43.53.34.94.7
Body weight1.98.213.42.72.72.2-2.1-3.7-3.2-3.2-2.9-2.9-2.93.5-3.53.3-3.3-3.31.43.22.61.12.62.1
Weight adjusted by age0.40.51.00.00.0-0.90.70.00.70.71.01.01.0-0.60.6-0.80.80.7-0.7-0.2-0.9-0.3-0.8-0.9
Bone surface2.85.08.4-2.0-2.0-0.80.72.42.62.52.02.02.0-2.72.7-2.22.42.5-1.0-2.5-2.0-2.5-2.9-2.9
Bone volume1.93.25.9-1.5-1.5-0.50.41.82.12.01.71.71.7-2.22.2-1.62.02.0-0.7-1.7-1.5-2.1-2.3-2.4
Breakpoint value in progressive ratio session0.50.52.3-0.3-0.3-1.51.00.10.80.80.80.80.8-0.70.7-1.10.70.7-0.5-0.2-0.70.4-0.4-0.1
Number of licking bursts0.50.62.2-0.2-0.31.4-1.5-0.8-0.4-0.4-0.7-0.7-0.70.6-0.61.1-0.6-0.61.20.61.10.30.80.5
Context. condit. distance diff. score1.92.34.92.22.20.8-0.5-1.7-1.6-1.6-1.8-1.8-1.81.8-1.81.4-1.8-1.8-0.41.70.9-0.20.90.5
Locomotion velocity, session 11.01.13.00.40.4-1.71.70.90.70.80.80.80.8-0.50.5-1.30.70.6-1.7-0.7-1.6-1.1-1.4-1.0
Locomotion distance, session 10.50.61.91.41.3-0.50.50.1-0.2-0.2-1.0-1.0-1.00.4-0.4-0.1-0.7-0.7-1.40.3-0.3-1.1-0.3-0.3
Locomotion velocity, session 22.52.97.82.82.8-0.20.4-1.6-1.7-1.6-2.2-2.2-2.22.0-2.01.1-2.1-2.1-0.81.70.6-0.10.81.1
Locomotion distance, session 20.60.82.61.61.6-0.90.8-0.4-0.7-0.6-1.2-1.2-1.20.6-0.60.1-0.9-0.8-1.30.4-0.3-0.50.00.2
Locomotion velocity, session 30.40.51.81.31.3-1.21.2-0.0-0.4-0.3-0.7-0.7-0.70.2-0.2-0.3-0.4-0.4-0.90.5-0.2-0.20.00.5
Locomotion distance, session 30.20.20.80.60.6-0.90.90.3-0.10.0-0.0-0.0-0.0-0.30.3-0.40.10.1-0.9-0.2-0.7-0.8-0.6-0.4
Stereotopy head waving bouts, day 30.10.10.8-0.2-0.20.8-0.9-0.20.10.1-0.2-0.2-0.20.1-0.10.3-0.2-0.20.2-0.40.1-0.5-0.2-0.5
Stereotopy head waving duration, day 30.30.30.60.70.70.0-0.2-0.8-0.4-0.4-0.7-0.7-0.70.7-0.70.3-0.7-0.7-0.10.50.20.60.50.3
Locomotion velocity, session 70.90.92.2-0.2-0.2-0.60.81.30.91.00.50.50.5-1.01.0-1.00.80.8-1.2-1.1-1.1-1.5-1.4-1.4
Locomotion distance, session 70.40.62.70.80.8-1.21.40.50.20.20.20.20.2-0.20.2-0.70.20.2-1.6-0.2-1.1-0.9-0.8-0.8
Stereotopy head waving bouts, day 70.50.51.20.90.90.7-0.7-1.1-0.6-0.6-1.0-1.0-1.00.7-0.70.7-0.8-0.8-0.40.60.30.10.3-0.4
Stereotopy head waving duration, day 70.20.21.10.10.10.9-1.0-0.6-0.3-0.2-0.6-0.6-0.60.2-0.20.6-0.4-0.40.20.10.4-0.10.2-0.2
Locomotion velocity, session 80.50.62.90.20.2-0.30.30.90.60.8-0.2-0.2-0.2-0.90.9-0.60.40.5-1.1-0.6-0.7-1.7-1.2-1.2
Locomotion distance, session 81.31.86.62.62.6-0.30.5-0.9-1.3-1.2-1.8-1.8-1.81.2-1.20.6-1.5-1.4-1.51.00.1-1.20.10.2
Degree of sensitization distance0.10.10.60.60.6-0.50.7-0.0-0.0-0.00.00.00.00.3-0.3-0.2-0.1-0.2-0.70.2-0.4-0.0-0.2-0.2
Degree of sensitization stereotypy0.20.30.80.70.70.2-0.2-0.6-0.4-0.4-0.9-0.9-0.90.3-0.30.3-0.6-0.5-0.60.1-0.1-0.2-0.0-0.5
Conditioned locomotion1.01.23.1-0.1-0.1-1.71.71.20.80.90.90.90.9-1.01.0-1.40.90.9-1.3-1.3-1.5-0.9-1.3-0.9
Cocaine response after cond. corrected0.50.62.2-0.9-0.90.4-0.5-0.10.60.61.51.51.5-0.50.5-0.10.90.90.80.00.30.70.20.1
Cocaine response after cond. not corrected0.80.92.9-1.1-1.10.1-0.20.11.11.01.71.71.7-0.70.7-0.61.21.10.6-0.3-0.10.5-0.2-0.3
Cocaine response before conditioning0.91.12.3-0.5-0.5-1.21.21.11.41.20.80.80.8-1.11.1-1.50.91.0-1.1-0.9-1.4-0.6-1.3-1.2
Saline control response0.30.41.4-0.1-0.1-1.01.20.60.80.7-0.1-0.1-0.1-0.80.8-1.00.40.5-0.50.0-0.7-0.4-0.7-0.5
Bone: connectivity density0.91.42.4-1.5-1.6-0.0-0.01.31.41.31.21.21.2-1.41.4-1.01.31.30.0-1.3-0.8-0.9-1.3-1.3
Bone: cortical apparent density0.30.41.4-0.4-0.40.3-0.10.70.40.40.10.10.1-0.60.6-0.20.40.4-0.5-1.1-0.6-1.1-0.9-1.2
Bone: cortical area0.50.75.90.70.70.1-0.00.50.50.4-0.2-0.2-0.2-0.70.7-0.30.30.3-1.4-0.4-0.6-2.4-1.3-1.5
Bone: cortical porosity1.41.52.90.80.90.5-0.5-1.1-1.6-1.5-1.2-1.2-1.21.3-1.31.3-1.3-1.20.91.21.31.31.61.7
Bone: cortical porosity0.70.81.80.80.80.1-0.1-0.8-1.2-1.2-0.6-0.6-0.60.9-0.90.9-0.8-0.80.41.00.81.11.21.3
Bone: cortical thickness0.61.03.41.91.80.1-0.0-0.5-0.8-0.8-1.3-1.3-1.30.5-0.50.6-0.9-0.8-1.50.5-0.2-1.7-0.4-0.6
Bone: cortical thickness0.30.32.7-0.2-0.30.8-0.70.70.10.1-0.1-0.1-0.1-0.50.50.30.20.3-0.0-1.0-0.0-1.7-0.7-0.8
Bone: cortical tissue density0.20.31.2-0.4-0.50.3-0.10.70.30.30.10.10.1-0.60.6-0.20.40.4-0.4-1.0-0.6-0.9-0.8-1.1
Condit. Reinf. active minus inactive responses1.01.11.9-0.4-0.50.1-0.10.71.31.31.31.31.3-1.31.3-0.71.31.3-0.9-0.7-0.5-1.3-1.1-1.4
Condit. Reinf. active-inactive response ratio0.60.61.9-0.7-0.80.7-0.70.10.70.71.41.41.4-0.90.9-0.11.11.10.1-0.30.1-0.2-0.2-0.6
Condit. Reinf. active responses0.30.41.20.10.00.2-0.20.40.90.90.60.60.6-0.90.9-0.40.80.8-0.60.0-0.1-1.1-0.7-0.8
Condit. Reinf. inactive responses0.50.61.60.80.80.1-0.3-0.4-0.5-0.5-1.3-1.3-1.30.6-0.60.4-0.9-0.90.31.30.70.20.50.6
Incentive salience index mean0.20.31.20.30.30.0-0.00.40.60.60.30.30.3-0.80.8-0.30.60.6-0.8-0.0-0.1-1.1-0.6-0.6
Condit. Reinf. lever presses0.60.82.21.11.10.0-0.0-0.5-0.8-0.8-1.5-1.5-1.50.5-0.50.6-1.0-0.90.01.20.70.20.70.9
Condit. Reinf. active minus inactive responses0.60.71.5-0.1-0.1-0.40.50.80.70.71.21.21.2-0.60.6-0.60.90.9-1.2-0.8-0.8-0.9-0.8-1.1
Condit. Reinf. active-inactive response ratio0.40.41.30.0-0.00.2-0.20.10.40.51.11.11.1-0.20.2-0.10.70.6-0.8-0.3-0.4-0.7-0.5-1.1
Condit. Reinf. active responses0.91.22.4-0.1-0.1-1.21.51.10.90.91.11.11.1-0.80.8-1.21.01.0-1.6-1.3-1.4-1.0-1.2-1.1
Condit. Reinf. inactive responses0.60.72.4-0.1-0.1-1.41.60.90.60.50.20.20.2-0.60.6-1.10.40.5-1.0-1.3-1.3-0.9-1.1-0.6
Condit. Reinf. lever presses0.10.10.70.60.6-0.20.3-0.0-0.2-0.3-0.4-0.4-0.40.2-0.20.1-0.3-0.3-0.8-0.3-0.3-0.6-0.2-0.2
Condit. Reinf. lever reinforcers received0.71.02.30.00.0-1.11.31.10.80.81.01.01.0-0.70.7-1.10.90.9-1.5-1.1-1.3-1.1-1.1-1.0
Conditioned reinforcement - actives0.70.72.30.80.8-1.51.10.20.80.70.60.60.6-0.70.7-1.00.70.7-1.50.2-1.0-0.2-0.8-1.0
Conditioned reinforcement - inactives0.20.21.00.90.9-0.40.5-0.60.10.10.10.10.10.3-0.3-0.2-0.1-0.1-1.00.6-0.40.2-0.1-0.3
Conditioned locomotion0.00.00.20.30.30.1-0.5-0.40.0-0.0-0.0-0.0-0.0-0.10.10.20.00.00.00.20.2-0.10.0-0.2
Patch foraging indifference point 0 sec0.40.71.30.90.90.00.4-1.1-1.0-1.1-1.0-1.0-1.01.1-1.10.6-1.0-1.0-0.40.4-0.20.80.50.0
Patch foraging indifference point AUC1.01.26.11.71.7-2.12.00.0-0.4-0.3-0.1-0.1-0.10.3-0.3-0.7-0.2-0.2-2.5-0.7-1.5-0.1-0.5-0.7
Delay disc. indifference point, 0s delay2.42.76.5-0.5-0.5-1.92.01.71.31.41.31.31.3-1.71.7-1.91.51.5-2.5-1.7-2.5-0.1-1.4-2.2
Delay disc. indifference point, 16s delay1.61.64.1-1.3-1.3-1.82.01.71.21.21.41.41.4-0.90.9-1.71.21.1-0.1-1.4-1.30.4-0.80.1
Delay disc. indifference point, 2s delay1.31.45.7-0.3-0.3-2.32.41.51.00.80.80.80.8-0.80.8-1.70.80.9-1.4-1.0-1.80.6-0.8-0.5
Delay disc. indifference point, 24s delay0.20.21.80.60.6-1.11.3-0.1-0.3-0.4-0.3-0.3-0.30.1-0.1-0.4-0.2-0.2-0.30.1-0.40.0-0.30.3
Delay disc. indifference point, 4s delay1.31.47.20.20.3-2.72.61.60.80.50.40.40.4-0.30.3-1.50.40.4-1.8-1.1-1.90.5-0.7-0.3
Delay disc. indifference point, 8s delay3.13.27.2-0.8-0.7-2.72.62.41.51.71.71.71.7-1.71.7-2.41.71.7-1.5-1.4-2.3-0.8-2.0-1.3
Indifference point function ln k0.81.13.3-0.4-0.41.2-0.8-1.1-0.8-0.9-0.5-0.5-0.50.8-0.81.0-0.7-0.71.71.21.21.81.51.3
Indifference point function log k0.81.13.3-0.4-0.41.2-0.8-1.1-0.8-0.9-0.5-0.5-0.50.8-0.81.0-0.7-0.71.71.21.21.81.51.3
Patch foraging total patch changes 0 sec0.50.91.71.01.0-0.00.4-1.2-1.2-1.3-1.0-1.0-1.01.2-1.20.7-1.2-1.2-0.50.4-0.20.80.60.1
Patch foraging total patch changes 12 sec1.41.85.02.22.2-0.91.1-1.0-1.4-1.4-1.7-1.7-1.71.4-1.40.6-1.6-1.5-1.70.3-0.6-0.5-0.0-0.3
Patch foraging total patch changes 18 sec0.50.72.90.70.7-1.01.20.10.40.30.60.60.6-0.30.3-0.80.40.4-1.7-0.8-1.3-0.8-1.0-1.3
Patch foraging total patch changes 24 sec1.01.23.51.91.9-0.91.0-0.7-1.1-1.1-1.2-1.2-1.21.2-1.20.4-1.2-1.2-1.4-0.1-0.6-0.40.0-0.1
Patch foraging total patch changes 6 sec1.21.74.02.02.0-0.50.7-1.5-1.5-1.6-1.6-1.6-1.61.4-1.40.8-1.6-1.5-1.30.7-0.30.20.40.0
Patch foraging time to switch 0 sec1.92.97.8-2.8-2.80.8-0.92.02.02.01.71.71.7-1.81.8-0.81.81.81.7-1.40.1-1.6-1.3-0.4
Patch foraging water rate 0 sec1.42.38.32.92.8-1.31.5-1.5-1.4-1.5-1.3-1.3-1.31.0-1.00.1-1.2-1.1-2.90.6-1.30.1-0.1-1.1
Patch foraging water rate 12 sec2.84.312.63.63.5-0.20.1-2.6-2.4-2.4-2.1-2.1-2.12.1-2.11.6-2.2-2.1-1.62.80.50.81.40.3
Patch foraging water rate 18 sec1.52.13.81.71.70.1-0.1-1.9-1.9-1.9-1.7-1.7-1.71.5-1.51.3-1.6-1.6-0.21.60.51.11.30.6
Patch foraging water rate 24 sec3.04.16.82.12.11.1-0.7-2.5-2.6-2.6-2.4-2.4-2.42.1-2.12.1-2.3-2.20.02.11.31.82.31.3
Patch foraging water rate 6 sec0.40.52.81.41.3-0.80.7-0.2-0.5-0.6-0.7-0.7-0.70.1-0.1-0.2-0.4-0.3-1.70.2-0.7-0.1-0.1-0.8
Seeking ratio, delayed vs. immediate footshock0.00.10.2-0.0-0.1-0.1-0.40.2-0.3-0.3-0.0-0.0-0.0-0.30.30.20.10.20.20.40.10.40.1-0.2
Distance traveled before self-admin1.11.11.81.01.01.1-1.0-1.1-1.3-1.3-1.4-1.4-1.41.2-1.21.3-1.3-1.20.30.70.9-0.70.60.5
Distance traveled after self-admin0.30.32.00.80.80.0-0.0-0.7-0.2-0.3-0.5-0.5-0.50.3-0.30.1-0.4-0.4-0.31.40.30.70.50.1
Extensor digitorum longus weight0.20.71.41.00.91.2-0.8-1.2-0.9-0.8-0.8-0.8-0.80.9-0.91.1-0.9-0.90.01.10.8-0.40.60.2
Bone: elastic displacement0.30.30.9-0.2-0.20.9-0.8-0.1-0.3-0.3-0.7-0.7-0.70.4-0.40.6-0.5-0.50.90.20.9-0.20.40.8
Bone: elastic work1.31.76.0-0.1-0.12.5-2.2-0.5-0.8-0.8-1.3-1.3-1.30.7-0.71.7-1.0-1.01.80.72.1-0.80.91.4
Bone: endosteal estimation1.12.44.4-2.1-2.10.3-0.41.72.01.81.71.71.7-1.91.9-1.21.81.80.4-1.6-0.6-1.2-1.3-1.4
Bone: endosteal perimeter1.32.84.8-1.6-1.6-0.10.11.82.22.01.61.61.6-2.22.2-1.62.02.0-0.2-1.5-1.0-1.6-1.8-1.9
Epididymis fat weight2.45.69.71.91.92.4-2.4-2.9-3.0-2.9-1.9-1.9-1.92.9-2.93.1-2.5-2.61.52.42.50.72.21.9
Delta time in closed arm before/after self-admin0.50.51.40.50.60.0-0.1-0.4-1.2-1.1-0.6-0.6-0.60.8-0.80.9-0.7-0.70.60.30.50.60.80.9
Delta time in open arm before/after self-admin0.60.63.60.10.1-1.71.90.60.30.3-0.0-0.0-0.0-0.60.6-1.20.30.4-1.0-0.1-1.01.1-0.2-0.1
Diff in mean of infusions in LGA sessions0.30.30.7-0.8-0.80.4-0.60.00.40.40.70.70.7-0.60.6-0.00.60.60.5-0.10.40.80.40.3
Delay discount exponential model param2.32.59.00.30.33.0-3.0-2.1-1.2-1.2-1.2-1.2-1.21.0-1.02.1-1.1-1.11.51.52.30.51.70.8
Extinction: sum of active levers before priming0.60.61.8-0.8-0.7-0.70.41.40.80.80.60.60.6-1.21.2-0.90.91.0-0.2-0.9-0.5-0.4-0.7-0.4
Active lever presses in extinction session 60.10.10.80.60.6-0.40.5-0.10.20.20.20.20.20.3-0.3-0.2-0.1-0.1-0.30.90.10.20.10.5
Bone: final force0.30.54.60.80.71.0-0.9-0.2-0.2-0.2-0.4-0.4-0.40.1-0.10.5-0.2-0.2-0.7-0.10.1-2.1-0.6-0.9
Bone: final moment0.30.54.80.90.90.7-0.6-0.1-0.2-0.2-0.5-0.5-0.50.1-0.10.4-0.3-0.2-1.0-0.2-0.1-2.2-0.7-1.1
Food consumed during 24 hour testing period0.20.21.00.10.1-0.20.3-0.3-0.10.0-1.0-1.0-1.00.1-0.1-0.1-0.5-0.4-0.00.4-0.10.50.1-0.1
Glucose2.03.05.62.22.20.6-0.8-2.4-2.0-2.0-1.6-1.6-1.62.3-2.31.8-2.0-2.1-0.11.91.10.81.61.1
Heart weight1.11.63.9-1.5-1.5-0.10.11.31.31.31.31.31.3-1.21.2-1.01.31.3-0.1-2.0-1.1-1.4-1.5-1.5
Delay discount hyperbolic model param2.52.79.70.30.33.1-3.1-2.1-1.3-1.2-1.2-1.2-1.21.1-1.12.2-1.2-1.21.61.62.40.31.60.8
Intermittent access intake day 1-15 change0.20.20.5-0.3-0.40.1-0.3-0.20.60.60.70.70.7-0.40.4-0.20.50.50.30.20.1-0.1-0.2-0.2
Intermittent access intake escalation0.70.71.4-1.1-1.10.4-0.50.31.01.11.21.21.2-0.90.9-0.51.11.00.7-0.10.2-0.0-0.3-0.4
Intermittent access intake escalation 20.30.30.6-0.1-0.1-0.40.50.40.50.60.60.60.6-0.60.6-0.60.60.6-0.3-0.2-0.5-0.7-0.8-0.6
Intermitt. access day 1 inactive lever presses0.60.72.7-0.7-0.71.5-1.6-0.2-0.2-0.1-0.3-0.3-0.30.1-0.11.0-0.2-0.21.50.81.50.61.00.9
Intermitt. access day 15 inactive lever presses0.50.51.1-0.1-0.10.5-0.6-0.8-0.7-0.6-0.8-0.8-0.81.0-1.00.9-0.9-1.00.40.20.50.90.90.5
Intermitt. access escalation Index1.21.12.50.60.60.3-0.4-0.8-1.3-1.3-1.0-1.0-1.01.1-1.11.0-1.1-1.10.61.10.91.61.61.2
Intermittent access day 1 total infusions0.40.41.30.40.40.4-0.3-1.0-0.4-0.5-0.4-0.4-0.40.6-0.60.5-0.5-0.50.81.10.81.10.80.9
Intermittent access day 15 total infusions0.30.41.6-0.6-0.60.7-0.8-0.60.40.40.60.60.6-0.20.20.10.40.31.30.80.80.60.30.4
Intermittent access terminal intake (last 3 days)0.20.20.7-0.1-0.10.5-0.5-0.80.30.20.30.30.30.1-0.10.10.10.00.90.80.60.40.30.5
Intermittent access total infusions0.30.32.4-0.1-0.1-0.10.1-0.80.10.00.20.20.20.1-0.1-0.10.0-0.00.81.00.51.60.70.9
Intermittent access day 1 locomotion0.60.71.50.10.10.8-0.8-0.7-0.6-0.6-0.5-0.5-0.50.8-0.80.9-0.7-0.71.10.81.21.21.21.2
Intermittent access day 15 total locomotion0.20.30.5-0.6-0.60.1-0.00.30.70.60.70.70.7-0.60.6-0.40.70.60.6-0.40.1-0.1-0.30.0
Intermittent access total locomotion0.30.30.7-0.8-0.8-0.30.20.30.70.60.80.80.8-0.60.6-0.60.70.70.5-0.5-0.20.3-0.3-0.0
Intermittent access standard deviation0.60.61.2-0.9-0.90.1-0.00.61.01.01.11.11.1-0.80.8-0.70.90.90.5-0.5-0.2-0.6-0.8-0.4
Left kidney weight0.31.02.01.11.2-0.40.5-1.1-1.1-1.2-1.4-1.4-1.41.0-1.00.5-1.2-1.2-0.31.10.00.70.50.3
Right kidney weight0.30.92.31.31.3-1.11.1-0.9-1.0-1.1-1.2-1.2-1.20.7-0.70.1-0.9-0.9-1.50.6-0.90.60.1-0.6
Cocaine induced anxiety0.20.20.9-0.8-0.80.4-0.40.10.50.50.50.50.5-0.10.1-0.00.30.30.30.10.40.90.50.5
Post-drug Anxiety1.31.54.9-2.2-2.21.6-1.70.91.11.11.31.31.3-0.80.80.11.11.01.3-0.90.6-0.7-0.3-0.2
Baseline Anxiety1.51.66.5-1.4-1.41.0-0.91.21.11.11.21.21.2-1.21.2-0.41.21.20.6-1.4-0.2-2.5-1.6-1.3
Tail length1.54.66.42.42.41.6-1.3-2.3-2.4-2.5-2.4-2.4-2.42.5-2.52.4-2.5-2.51.02.51.90.11.61.6
Length with tail0.20.85.0-0.3-0.32.1-1.9-0.50.30.20.30.30.3-0.10.10.60.20.20.9-0.10.7-2.2-0.9-1.1
Length without tail2.45.37.9-2.7-2.81.3-1.41.42.62.72.62.62.6-2.62.6-1.42.62.60.3-2.3-0.8-2.8-2.4-2.7
Times rat made contact with spout0.50.51.20.50.50.3-0.3-1.1-0.9-0.9-0.4-0.4-0.41.0-1.00.7-0.7-0.80.61.00.61.00.90.8
Lifetime Intake0.20.21.3-0.3-0.3-0.30.2-0.30.50.40.60.60.6-0.20.2-0.40.40.40.50.50.11.10.30.4
Liver weight, left0.30.41.61.31.3-0.30.6-0.8-0.7-0.8-0.5-0.5-0.50.7-0.70.2-0.7-0.7-0.40.70.0-0.30.20.4
Liver weight, right0.60.93.20.30.31.8-1.4-1.1-0.5-0.5-0.8-0.8-0.80.6-0.61.0-0.7-0.71.11.31.8-0.11.01.2
Locomotor activity1.21.95.70.30.32.4-2.3-1.1-1.3-1.3-1.4-1.4-1.41.2-1.22.1-1.3-1.31.30.91.8-0.51.00.8
Locomotor testing distance1.01.75.70.70.72.4-2.1-0.9-1.4-1.3-1.4-1.4-1.41.0-1.02.0-1.2-1.20.60.51.4-1.60.4-0.0
Locomotor testing rearing1.11.73.51.71.71.6-1.5-1.3-1.6-1.6-1.3-1.3-1.31.1-1.11.9-1.3-1.2-0.31.21.2-0.60.90.1
Locomotion in novel chamber0.50.65.01.01.0-2.21.80.20.0-0.1-0.2-0.2-0.20.1-0.1-0.8-0.1-0.1-1.20.4-0.90.5-0.10.4
Locomotion in novel chamber post-restriction3.34.07.0-0.9-0.9-2.32.41.92.32.32.22.22.2-2.52.5-2.62.42.4-1.4-0.6-2.10.1-1.9-1.7
Fecal boli incidents, locomotor time 10.40.42.10.70.7-0.90.80.4-0.2-0.20.00.00.0-0.50.5-0.40.30.3-1.4-0.6-1.0-0.9-0.7-1.0
Change in fecal boli incidents, locomotor task0.80.71.7-1.0-1.0-0.90.80.51.31.31.01.01.0-0.70.7-1.00.90.80.50.1-0.41.3-0.10.3
Time >=10cm from walls, locomotor time 10.00.00.20.20.2-0.10.4-0.20.10.1-0.0-0.0-0.0-0.00.0-0.20.00.0-0.3-0.0-0.30.30.1-0.1
Bouts of movement, locomotor time 10.40.41.00.90.9-1.00.8-0.6-0.7-0.7-0.5-0.5-0.50.6-0.6-0.1-0.6-0.6-0.50.5-0.20.90.40.2
Total resting periods, locomotor time 10.20.30.70.80.8-0.60.3-0.7-0.6-0.6-0.4-0.4-0.40.5-0.50.1-0.5-0.5-0.50.3-0.20.60.3-0.2
Rest time, locomotor task time 11.01.15.00.30.3-2.21.70.80.30.40.60.60.6-0.50.5-1.10.60.6-1.9-1.1-1.70.7-0.6-1.2
Distance moved, locomotor task time 10.60.72.10.70.71.1-0.3-0.9-0.3-0.4-0.5-0.5-0.51.0-1.00.6-0.8-0.80.71.41.10.10.81.4
Vertical activity count, locomotor time 10.60.73.0-0.0-0.01.2-0.8-0.4-0.0-0.1-0.4-0.4-0.40.5-0.50.6-0.4-0.51.61.41.50.10.81.7
Time >=10cm from walls, locomotor time 20.10.10.2-0.3-0.30.5-0.4-0.10.00.00.10.10.10.2-0.20.1-0.1-0.10.4-0.00.30.40.40.4
Bouts of movement, locomotor time 20.60.62.01.41.4-0.40.8-0.8-1.0-1.0-1.0-1.0-1.00.5-0.50.2-0.8-0.7-0.90.6-0.3-0.2-0.0-0.1
Total resting periods, locomotor time 20.40.51.11.01.0-0.30.6-0.6-1.0-1.0-1.0-1.0-1.00.4-0.40.2-0.7-0.7-0.50.6-0.10.30.20.1
Rest time, locomotor task time 20.40.42.4-0.1-0.1-1.50.90.80.00.10.00.00.0-0.60.6-0.50.30.4-0.7-1.1-1.00.6-0.3-0.7
Distance moved, locomotor task time 20.10.10.50.10.10.7-0.1-0.10.30.20.20.20.20.1-0.1-0.10.00.0-0.00.70.4-0.10.20.4
Vertical activity count, locomotor time 20.80.81.8-1.1-1.10.5-0.21.01.31.31.21.21.2-1.01.0-0.81.11.10.3-0.30.0-0.6-0.5-0.1
Light reinforcement 10.30.61.71.01.00.2-0.0-0.5-0.8-0.9-1.3-1.3-1.30.4-0.40.6-0.8-0.8-0.11.00.50.10.40.2
Light reinforcement 20.50.71.40.20.21.0-0.9-0.7-0.7-0.7-1.1-1.1-1.10.5-0.50.9-0.8-0.80.71.21.10.50.90.7
Bone: marrow area1.22.64.4-2.1-2.10.3-0.41.82.01.91.71.71.7-1.91.9-1.21.91.90.3-1.7-0.6-1.4-1.4-1.4
Bone: maximum diameter1.12.04.3-0.4-0.4-1.11.01.41.61.50.80.80.8-1.81.8-1.61.41.4-1.5-1.2-1.6-1.6-1.8-2.1
Bone: maximum force0.30.52.9-0.0-0.11.6-1.5-0.1-0.1-0.1-0.5-0.5-0.5-0.10.10.8-0.2-0.10.4-0.10.8-1.7-0.1-0.3
Bone: maximum moment0.20.42.50.10.11.4-1.3-0.1-0.2-0.2-0.6-0.6-0.60.0-0.00.8-0.3-0.30.2-0.10.6-1.6-0.1-0.3
Mean time between licks in bursts0.81.13.3-1.8-1.8-0.20.11.11.21.11.11.11.1-1.21.2-0.91.21.20.6-1.2-0.5-0.3-0.8-0.5
Mean num. licks in bursts0.30.42.10.40.5-1.41.50.1-0.0-0.10.60.60.6-0.10.1-0.70.30.3-0.9-0.1-0.90.4-0.3-0.2
Cd content in liver1.21.32.5-1.4-1.4-1.01.01.61.41.41.01.01.0-1.51.5-1.51.31.3-0.3-1.0-0.80.2-0.7-0.4
Co content in liver1.01.15.00.00.10.3-0.3-0.8-0.8-0.8-0.9-0.9-0.90.7-0.70.7-0.8-0.81.21.21.32.21.82.0
Cu content in liver0.40.51.0-0.3-0.3-1.01.00.70.70.70.50.50.5-0.90.9-1.00.70.8-0.6-0.4-0.8-0.4-0.8-0.6
Fe content in liver0.20.31.11.01.0-0.50.4-0.3-0.5-0.5-0.4-0.4-0.40.5-0.50.1-0.4-0.5-0.50.3-0.1-0.7-0.20.3
K content in liver0.80.83.7-1.3-1.31.9-1.70.20.10.10.10.10.1-0.40.40.70.20.31.9-0.31.2-0.80.10.4
Mg content in liver0.10.11.2-0.1-0.10.4-0.00.2-0.1-0.0-0.3-0.3-0.3-0.20.20.1-0.0-0.00.2-0.3-0.0-1.1-0.5-0.2
Mn content in liver0.10.11.6-0.5-0.6-0.20.1-0.2-0.0-0.10.20.20.20.0-0.00.00.10.10.20.1-0.21.30.4-0.1
Na content in liver0.60.61.41.11.10.5-0.4-0.7-0.5-0.7-1.2-1.2-1.20.7-0.70.6-0.9-0.9-0.20.70.4-1.0-0.0-0.0
Rb content in liver2.12.64.5-2.1-2.0-0.40.82.01.71.91.41.41.4-2.12.1-1.61.81.90.3-1.7-0.9-1.6-1.8-0.9
Se content in liver0.81.03.80.90.9-1.92.00.40.1-0.0-0.2-0.2-0.2-0.10.1-1.0-0.0-0.0-1.9-0.7-1.7-0.5-1.1-1.2
Sr content in liver0.10.10.3-0.2-0.20.6-0.50.0-0.0-0.1-0.4-0.4-0.40.1-0.10.3-0.2-0.20.10.20.40.40.50.1
Zn content in liver2.83.06.30.00.0-2.32.41.61.41.41.31.31.3-1.61.6-2.11.51.5-2.5-1.7-2.5-1.6-2.3-2.3
Bone: minimum diameter1.12.14.9-1.1-1.10.1-0.21.51.91.71.41.41.4-1.81.8-1.21.61.6-0.6-1.5-0.9-2.2-1.8-1.8
Time in familiar zone, hab. session 12.92.75.72.12.1-0.50.7-1.4-1.7-1.8-2.4-2.4-2.41.7-1.70.9-2.0-2.0-0.21.90.51.31.31.3
Time in novel zone, hab. session 12.12.04.4-1.9-1.90.2-0.21.21.61.62.12.12.1-1.41.4-0.91.81.70.1-1.7-0.6-0.4-0.8-1.0
Total zone transitions, hab. session 11.11.53.51.91.90.1-0.1-1.2-1.3-1.1-1.7-1.7-1.71.2-1.20.9-1.4-1.4-0.71.30.6-0.20.80.6
Total locomotion distance, hab. session 11.01.54.42.12.10.1-0.3-1.6-1.1-1.1-1.3-1.3-1.31.3-1.31.0-1.3-1.4-0.91.30.5-0.30.70.3
Locomotion velocity, hab. session 10.81.13.81.91.90.2-0.5-1.5-0.9-0.9-1.1-1.1-1.11.1-1.10.9-1.1-1.1-0.91.20.5-0.70.40.2
Time in familiar zone, hab. session 20.40.42.8-0.7-0.70.9-0.9-0.2-0.2-0.2-0.2-0.2-0.20.1-0.10.6-0.2-0.21.70.51.00.80.61.0
Time in novel zone, hab. session 20.50.53.11.21.2-0.90.9-0.5-0.3-0.3-0.3-0.3-0.30.4-0.4-0.2-0.4-0.4-1.8-0.0-0.9-0.3-0.2-0.7
Total zone transitions, hab. session 20.20.31.30.20.21.0-1.1-0.2-0.4-0.3-0.5-0.5-0.50.5-0.50.8-0.5-0.50.20.30.6-0.50.3-0.0
Total locomotion distance, hab. session 20.30.40.70.60.60.6-0.8-0.7-0.4-0.5-0.7-0.7-0.70.7-0.70.7-0.7-0.70.00.80.60.10.50.0
Locomotion velocity, hab. session 20.10.10.60.20.20.6-0.8-0.3-0.1-0.2-0.3-0.3-0.30.4-0.40.4-0.3-0.30.10.40.4-0.00.2-0.2
Novel to familiar place preference ratio0.00.00.40.00.00.3-0.2-0.70.0-0.0-0.1-0.1-0.10.2-0.20.1-0.1-0.10.20.30.20.20.20.1
Novelty place preference0.10.10.60.20.20.6-0.4-0.8-0.2-0.2-0.4-0.4-0.40.4-0.40.3-0.4-0.40.30.40.4-0.10.20.2
Time in novel zone, NPP test0.20.20.90.40.40.3-0.1-0.9-0.4-0.4-0.6-0.6-0.60.5-0.50.3-0.5-0.50.00.40.20.10.30.2
Total zone transitions, NPP test0.81.13.31.81.80.2-0.3-0.7-1.1-1.0-1.3-1.3-1.31.2-1.20.9-1.2-1.2-0.90.60.2-1.00.1-0.1
Total locomotion distance, NPP test0.70.92.81.71.60.4-0.5-0.9-0.9-0.9-1.1-1.1-1.11.1-1.10.9-1.1-1.1-0.90.70.4-0.70.3-0.2
Locomotion velocity, NPP test0.71.02.01.41.41.2-1.3-0.7-0.8-0.9-0.9-0.9-0.91.0-1.01.2-1.0-1.0-0.40.60.8-1.40.2-0.2
Intraocular pressure0.50.63.4-1.2-1.20.4-0.6-0.30.50.50.80.80.8-0.10.10.00.40.31.10.20.71.91.01.0
Delta distance traveled before/after self-admin0.30.32.7-0.0-0.0-0.20.3-0.40.70.60.60.60.6-0.30.3-0.50.40.4-0.21.00.01.60.4-0.0
Delta ambulatory time before/after self-admin0.60.63.2-0.6-0.60.00.0-0.31.11.01.01.01.0-0.70.7-0.70.90.80.21.00.11.80.3-0.1
Parametrial fat weight4.69.013.33.23.21.6-1.6-3.5-3.4-3.3-3.7-3.7-3.73.4-3.43.1-3.6-3.60.53.12.21.42.82.0
Pavlov. Cond. lever latency0.60.72.7-1.6-1.60.7-0.80.30.50.51.21.21.2-0.50.5-0.10.80.81.0-0.70.20.60.2-0.0
Pavlov. Cond. magazine entry latency0.30.42.20.90.9-1.11.10.10.20.3-0.1-0.1-0.1-0.30.3-0.60.10.1-1.50.3-0.9-0.3-0.6-0.8
Pavlov. Cond. change in total contacts0.40.41.21.11.1-0.70.7-0.3-0.3-0.3-1.0-1.0-1.00.3-0.3-0.0-0.6-0.6-0.90.7-0.30.10.1-0.1
Pavlov. Cond. index score0.50.62.31.51.5-0.80.9-0.2-0.2-0.1-0.8-0.8-0.80.1-0.1-0.2-0.4-0.4-1.50.7-0.6-0.6-0.4-0.6
Pavlov. Cond. latency score0.50.62.81.41.4-0.91.10.0-0.00.0-0.6-0.6-0.6-0.00.0-0.4-0.3-0.2-1.70.3-0.8-1.1-0.7-0.7
Pavlov. Cond. lever contacts0.80.92.61.61.6-0.30.4-0.6-0.8-0.8-1.4-1.4-1.40.8-0.80.5-1.1-1.1-0.51.10.3-0.30.30.5
Pavlov. Cond. magazine entry number0.30.31.8-1.0-1.00.8-0.90.1-0.3-0.30.10.10.10.1-0.10.5-0.0-0.01.4-0.60.70.20.40.7
Pavlov. Cond. intertrial magazine entries0.20.30.70.10.10.1-0.1-0.3-0.4-0.5-0.9-0.9-0.90.3-0.30.2-0.6-0.60.60.30.50.40.50.8
Pavlov. Cond. lever-magazine prob. diff.0.40.51.81.31.3-0.80.9-0.3-0.1-0.1-0.7-0.7-0.70.1-0.1-0.3-0.3-0.3-1.30.8-0.5-0.3-0.3-0.4
Pavlov. Cond. response bias0.50.72.21.51.5-0.40.5-0.6-0.7-0.6-1.0-1.0-1.00.7-0.70.3-0.8-0.8-0.71.20.10.20.30.2
Pavlov. Cond. lever latency0.10.21.5-0.5-0.4-0.80.80.30.10.2-0.1-0.1-0.1-0.20.2-0.50.10.10.3-0.1-0.21.20.20.4
Pavlov. Cond. magazine entry latency0.60.72.71.41.40.9-0.9-0.6-0.8-0.8-0.6-0.6-0.60.8-0.81.1-0.7-0.7-0.60.40.5-1.60.00.0
Pavlov. Cond. change in total contacts0.40.61.51.01.01.1-1.0-0.8-0.9-0.9-0.3-0.3-0.30.9-0.91.2-0.6-0.7-0.00.30.7-1.20.20.1
Pavlov. Cond. index score0.81.02.61.61.60.9-0.9-0.9-1.1-1.1-1.0-1.0-1.01.0-1.01.3-1.0-1.0-0.60.50.6-1.50.2-0.1
Pavlov. Cond. latency score1.01.22.81.71.61.0-1.0-0.9-1.2-1.2-1.0-1.0-1.01.2-1.21.4-1.1-1.1-0.50.70.7-1.30.30.1
Pavlov. Cond. lever contacts0.30.42.00.70.71.0-1.0-0.5-0.5-0.6-0.3-0.3-0.30.5-0.50.8-0.4-0.4-0.10.20.5-1.4-0.1-0.2
Pavlov. Cond. magazine entry number0.60.74.5-1.2-1.2-0.90.90.30.70.70.50.50.5-0.70.7-1.00.60.60.6-0.0-0.42.10.30.3
Pavlov. Cond. intertrial magazine entries0.20.31.6-1.0-1.0-0.10.1-0.20.60.50.30.30.3-0.40.4-0.50.40.40.6-0.1-0.21.30.0-0.3
Pavlov. Cond. lever-magazine prob. diff.1.01.22.61.61.61.0-1.0-1.0-1.2-1.2-1.1-1.1-1.11.2-1.21.4-1.2-1.2-0.40.70.8-1.30.40.2
Pavlov. Cond. response bias0.30.55.70.40.40.8-0.70.10.0-0.00.20.20.2-0.10.10.40.10.1-0.5-0.5-0.1-2.4-0.9-0.9
Time in closed arm before self-admin0.30.32.0-0.9-1.01.4-1.20.20.40.40.20.20.2-0.10.10.30.20.20.3-0.60.2-0.3-0.0-0.6
Time in closed arm after self-admin1.41.42.70.30.31.5-1.4-1.2-1.3-1.3-1.0-1.0-1.01.5-1.51.6-1.3-1.30.70.71.11.11.50.8
Time in open arm before self-admin0.30.31.41.21.2-0.00.1-0.6-0.1-0.10.10.10.10.6-0.60.1-0.3-0.3-0.11.00.4-0.6-0.00.5
Time in open arm after self-admin0.30.31.70.40.5-1.21.30.40.30.30.20.20.2-0.30.3-0.80.30.3-0.30.6-0.20.60.00.7
Bone: periosteal estimation0.91.84.6-0.8-0.9-0.0-0.01.51.71.51.11.11.1-1.71.7-1.11.51.5-0.8-1.4-1.0-2.1-1.7-1.9
Bone: periosteal perimeter0.40.74.2-0.3-0.30.8-0.80.80.90.80.20.20.2-1.21.2-0.30.70.8-0.2-0.5-0.0-2.0-1.1-1.3
Bone: post-yield work0.40.51.5-0.2-0.21.2-1.2-0.3-0.5-0.7-0.9-0.9-0.90.1-0.11.0-0.5-0.40.90.21.0-0.00.70.5
Progressive ratio test 1 active lever presses1.11.13.1-0.3-0.31.8-1.6-1.1-0.3-0.4-0.2-0.2-0.20.7-0.71.1-0.5-0.51.71.41.71.31.41.3
Progressive ratio test 1 breakpoint1.11.13.5-0.5-0.51.8-1.6-1.0-0.1-0.20.00.00.00.6-0.61.0-0.3-0.41.91.41.71.31.41.3
Progressive ratio test 1 inactive lever presses0.60.71.70.20.21.3-1.2-1.1-0.6-0.6-0.6-0.6-0.60.8-0.81.0-0.7-0.71.01.11.10.61.00.7
Progressive ratio test 2 active lever presses0.70.73.10.50.50.5-0.5-1.5-0.4-0.4-0.2-0.2-0.20.8-0.80.6-0.5-0.60.71.81.01.61.21.0
Progressive ratio test 2 breakpoint0.91.03.90.70.70.5-0.5-1.8-0.6-0.7-0.5-0.5-0.51.0-1.00.7-0.8-0.80.72.01.11.71.31.1
Progressive ratio test 2 inactive lever presses0.30.41.20.90.9-0.60.7-1.1-0.2-0.2-0.2-0.2-0.20.6-0.6-0.1-0.4-0.5-0.51.0-0.11.00.40.3
Incentive Sensitization - Responses1.61.63.91.71.7-0.30.3-2.0-1.3-1.2-1.1-1.1-1.11.5-1.50.7-1.3-1.4-0.21.90.51.61.31.0
Incentive Sensitization - Breakpoint1.31.33.21.61.6-0.40.4-1.8-1.1-1.0-0.9-0.9-0.91.4-1.40.6-1.2-1.2-0.41.70.31.41.00.8
Sum of active levers in priming session hrs 5-67.16.911.9-1.3-1.3-3.12.92.22.92.83.03.03.0-3.03.0-3.53.03.0-1.7-2.1-2.8-0.7-2.7-2.2
Progressive ratio1.21.48.5-1.1-1.21.4-1.21.20.80.91.01.01.0-0.70.7-0.10.80.80.6-1.4-0.0-2.9-1.5-1.1
Food seeking constrained by brief footshock1.31.52.8-1.3-1.31.7-1.11.01.61.61.51.51.5-1.21.2-0.61.41.30.5-0.70.2-1.5-1.0-0.9
Seeking ratio, punishment vs. effort0.10.21.30.30.4-0.30.4-0.30.30.20.00.00.0-0.20.2-0.30.10.2-0.50.7-0.01.10.40.2
Retroperitoneal fat weight1.03.46.72.62.60.6-0.8-2.4-2.3-2.3-1.6-1.6-1.62.4-2.41.9-2.1-2.1-0.31.91.20.31.51.1
Reaction time number correct1.42.09.41.41.4-2.52.70.50.00.1-0.1-0.1-0.1-0.30.3-1.50.10.1-3.1-0.9-2.4-0.4-1.2-1.8
Reaction time mean minus median0.40.52.3-0.7-0.81.4-1.50.50.30.20.30.30.3-0.10.10.60.20.20.6-0.80.4-1.4-0.3-0.4
Reaction time mean minus median AUC0.60.72.3-1.3-1.41.5-1.40.80.60.60.60.60.6-0.50.50.30.60.60.6-1.20.3-1.3-0.5-0.6
Reaction time num false alarms0.20.31.80.40.4-1.31.20.00.10.1-0.0-0.0-0.00.0-0.0-0.6-0.0-0.0-0.8-0.4-1.00.1-0.5-0.4
Reaction time num false alarms AUC0.20.31.80.50.5-1.31.3-0.1-0.1-0.1-0.4-0.4-0.40.3-0.3-0.4-0.3-0.3-0.6-0.3-0.80.4-0.20.1
Reaction time trials correct on left1.42.09.41.41.4-2.52.70.50.00.1-0.1-0.1-0.1-0.30.3-1.50.10.1-3.1-0.9-2.4-0.4-1.2-1.8
Reaction time trials on left1.31.99.31.51.5-2.52.60.4-0.00.1-0.1-0.1-0.1-0.20.2-1.40.10.1-3.0-0.8-2.4-0.4-1.2-1.7
Reaction time mean1.41.98.0-1.0-1.02.8-2.7-0.5-0.6-0.7-0.4-0.4-0.40.7-0.71.8-0.6-0.62.60.62.30.11.31.5
Reaction time mean AUC1.21.67.9-0.9-0.92.8-2.7-0.5-0.5-0.5-0.2-0.2-0.20.6-0.61.7-0.4-0.52.30.42.0-0.21.01.1
Median of all reaction times1.72.48.3-0.7-0.72.8-2.7-0.9-0.8-0.9-0.7-0.7-0.70.9-0.91.9-0.8-0.82.91.22.60.61.71.9
Reaction time omissions0.50.71.30.70.70.9-0.9-0.9-0.8-0.9-0.7-0.7-0.71.1-1.11.0-0.9-1.00.71.00.90.00.70.8
Reaction time false alarm rate0.10.10.8-0.4-0.40.0-0.2-0.2-0.0-0.1-0.1-0.1-0.10.3-0.30.3-0.2-0.20.90.00.40.50.40.8
Reaction time premature initiation rate0.20.30.70.20.20.3-0.4-0.1-0.7-0.7-0.4-0.4-0.40.7-0.70.8-0.6-0.60.3-0.20.5-0.20.50.8
Reaction time premature initiations0.30.41.21.01.0-0.70.7-0.0-0.8-0.7-0.5-0.5-0.50.6-0.60.2-0.6-0.6-1.1-0.5-0.6-0.4-0.0-0.2
Std. dev. reaction times0.91.26.3-0.9-0.92.5-2.5-0.1-0.3-0.4-0.1-0.1-0.10.5-0.51.5-0.3-0.31.90.01.7-0.70.70.9
Reaction time trials completed1.31.99.31.51.5-2.52.60.4-0.00.1-0.1-0.1-0.1-0.20.2-1.40.10.1-3.0-0.8-2.4-0.4-1.2-1.7
Reaction time trials AUC1.31.89.31.61.6-2.42.60.3-0.1-0.0-0.2-0.2-0.2-0.10.1-1.3-0.00.0-3.0-0.7-2.3-0.4-1.1-1.7
Run reversals in cocaine runway, females0.50.51.0-0.6-0.61.0-0.50.61.01.00.70.70.7-0.80.8-0.30.70.7-0.2-0.40.1-0.8-0.5-0.6
Run reversals in cocaine runway, males0.60.51.10.70.7-0.00.1-0.9-1.0-1.0-1.0-1.0-1.00.9-0.90.7-1.0-0.9-0.40.2-0.10.40.5-0.1
Latency to leave start box in cocaine runway2.12.37.1-0.1-0.12.7-2.4-1.1-1.3-1.3-1.5-1.5-1.50.7-0.71.9-1.1-1.11.81.42.40.81.91.4
Latency to leave start box in cocaine runway, F0.70.73.7-0.5-0.51.9-1.7-0.1-0.6-0.6-0.7-0.7-0.7-0.20.21.1-0.2-0.21.20.51.4-0.10.80.4
Latency to leave start box in cocaine runway, M2.92.84.01.11.11.7-1.6-1.8-1.6-1.7-1.9-1.9-1.91.6-1.61.8-1.8-1.71.01.92.01.22.01.7
Std. dev. time between licks in bursts0.81.01.8-1.2-1.2-0.70.81.31.31.10.90.90.9-1.21.2-1.21.11.1-0.1-0.9-0.6-0.1-0.6-0.2
Total sessions with >9 infusions0.10.10.30.20.20.1-0.2-0.1-0.3-0.4-0.4-0.4-0.40.4-0.40.3-0.4-0.40.20.10.30.40.50.5
Short access day 1 total inactive lever presses0.10.20.80.50.5-0.60.6-0.2-0.2-0.4-0.3-0.3-0.30.2-0.2-0.1-0.3-0.2-0.60.2-0.20.90.50.4
Short access day 10 total inactive lever presses0.30.41.10.70.7-0.50.1-0.1-0.6-0.6-1.0-1.0-1.00.4-0.40.4-0.7-0.6-0.8-0.2-0.2-0.20.1-0.1
Short access day 1 total infusions0.20.20.90.50.5-0.50.3-0.2-0.4-0.5-0.3-0.3-0.30.3-0.30.1-0.3-0.3-0.50.6-0.01.00.60.4
Short access day 10 total infusions0.20.21.0-0.5-0.50.4-0.2-0.40.30.30.40.40.40.0-0.0-0.10.20.11.00.60.61.00.40.7
Short access total infusions0.10.10.3-0.3-0.3-0.10.1-0.10.30.20.40.40.4-0.10.1-0.20.30.20.30.10.00.60.10.2
Short access day 1 locomotion0.20.20.8-0.6-0.60.1-0.50.90.40.30.20.20.2-0.60.6-0.20.40.40.3-0.80.1-0.5-0.1-0.1
Short access day 10 total locomotion0.50.61.2-0.6-0.60.00.10.91.11.11.01.01.0-0.50.5-0.70.70.7-0.0-0.8-0.4-0.9-0.9-0.6
Short access total locomotion0.50.51.3-0.6-0.6-0.40.31.10.80.70.70.70.7-0.70.7-0.70.70.7-0.3-1.1-0.6-0.7-0.8-0.7
One hour access (0.3 mA shock)0.60.83.00.50.5-1.71.4-0.20.90.90.70.70.7-0.80.8-1.30.80.8-1.00.3-1.00.3-0.7-0.5
Compulsive drug intake0.20.20.6-0.5-0.6-0.60.30.50.30.30.10.10.1-0.80.8-0.60.50.5-0.3-0.4-0.50.3-0.1-0.4
One hour access (shock baseline)0.20.32.20.70.70.00.0-1.20.0-0.10.10.10.10.3-0.30.1-0.1-0.20.11.50.40.80.30.3
Social response proportion0.20.20.8-0.6-0.6-0.10.10.50.90.70.50.50.5-0.50.5-0.70.50.50.5-0.1-0.1-0.2-0.50.0
Social responses0.30.41.1-0.5-0.40.1-0.20.90.60.40.80.80.8-0.50.5-0.30.60.60.9-0.10.4-1.1-0.50.5
Social time0.91.26.01.51.5-2.52.20.4-0.2-0.2-0.4-0.4-0.4-0.20.2-0.9-0.1-0.0-2.00.3-1.3-0.4-0.7-0.3
Soleus weight0.20.61.11.00.91.0-1.0-0.4-0.7-0.9-0.9-0.9-0.90.7-0.71.0-0.8-0.70.00.71.0-0.70.50.5
Bone: stiffness0.10.10.40.30.30.3-0.4-0.5-0.1-0.2-0.4-0.4-0.40.1-0.10.3-0.2-0.2-0.10.10.1-0.7-0.1-0.3
Tibialis anterior weight0.31.13.01.71.70.3-0.1-1.2-1.2-1.1-1.1-1.1-1.11.1-1.11.0-1.1-1.1-1.01.00.2-0.10.60.0
Time to tail flick, vehicle, before self-admin0.30.33.10.60.60.6-0.10.5-0.4-0.3-0.1-0.1-0.10.1-0.10.2-0.1-0.1-0.8-0.4-0.3-1.8-0.8-0.8
Time to tail flick, vehicle, after self-admin1.11.22.2-1.2-1.20.5-0.11.31.31.31.51.51.5-1.01.0-1.01.21.20.0-1.2-0.5-1.2-1.1-0.8
Time to tail flick, test, before self-admin4.54.410.4-0.9-0.9-3.22.72.22.32.22.42.42.4-1.81.8-2.92.12.1-2.0-1.5-2.60.1-1.6-1.4
Time to tail flick, test, after self-admin0.10.11.20.50.5-0.2-0.10.7-0.2-0.2-0.2-0.2-0.2-0.10.10.1-0.0-0.0-1.1-0.2-0.1-0.7-0.1-0.3
Delta time to tail flick, vehicle, before/after SA0.70.71.6-1.0-0.9-0.70.40.71.31.21.11.11.1-0.80.8-1.11.01.0-0.1-0.8-0.50.0-0.6-0.3
Delta time to tail flick, test, before/after SA4.23.87.41.31.32.4-2.2-1.7-2.4-2.3-2.3-2.3-2.31.8-1.82.7-2.0-2.01.21.72.3-0.01.71.6
Tibia length0.30.93.81.81.7-1.51.3-0.7-0.4-0.4-0.4-0.4-0.40.3-0.3-0.3-0.4-0.4-2.00.9-0.90.4-0.0-0.6
Ambulatory time before self-admin1.92.03.81.61.60.4-0.4-1.5-1.6-1.6-1.8-1.8-1.81.9-1.91.3-1.9-1.9-0.10.90.7-0.40.90.9
Ambulatory time after self-admin0.70.82.41.41.30.5-0.5-1.2-0.5-0.6-0.9-0.9-0.91.1-1.10.7-1.0-1.0-0.51.50.60.20.70.2
Bone: tissue strength0.40.40.90.70.7-0.10.2-0.7-1.0-0.9-0.8-0.8-0.80.7-0.70.6-0.8-0.80.10.50.30.40.50.7
Total heroin consumption0.00.00.20.10.1-0.30.1-0.50.0-0.00.00.00.0-0.20.2-0.20.10.10.40.40.30.20.00.3
Bone: trabecular number1.01.64.9-0.5-0.5-0.40.31.11.31.21.01.01.0-1.41.4-1.01.21.2-1.1-1.2-1.3-2.1-2.0-2.2
Bone: trabecular spacing1.01.32.51.31.3-0.60.7-1.2-1.3-1.4-1.1-1.1-1.11.6-1.60.6-1.4-1.4-0.10.80.31.21.11.4
Bone: trabecular thickness3.74.46.8-1.9-1.9-0.40.22.22.42.42.32.32.3-2.62.6-1.82.52.5-0.8-2.0-1.6-2.0-2.4-2.6
Bone: trabecular tissue density1.31.88.61.51.5-2.92.80.3-0.1-0.1-0.2-0.2-0.2-0.00.0-1.3-0.1-0.1-2.9-0.4-2.10.6-0.5-1.0
Water consumed over 24 hours1.11.33.11.81.8-0.50.8-1.3-1.0-1.0-1.7-1.7-1.71.0-1.00.4-1.3-1.2-0.81.2-0.20.10.2-0.0
Number of responses in last shaping day0.60.72.91.11.00.00.1-0.9-0.7-0.8-0.6-0.6-0.60.7-0.70.4-0.7-0.7-0.41.70.41.41.00.6