Hub : Genes

Slc1a7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	PL	alternative polyA	NM_001108973.1	0.02	0.01	5.7e-03	0	-0	-0	0.02	3.0e-01	6.0e-01	8.9e-01	3.5e-03
2	PL	alternative polyA	XM_017593537.2	0.02	0.01	4.1e-03	0.01	0	-0	0	1.6e-02	2.1e-01	6.9e-01	1.3e-01
3	PL	alternative polyA	NM_001108973.1	0.02	0.01	2.8e-03	0.01	0	-0	0	3.0e-02	1.4e-01	4.2e-01	1.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	0.6	1.1	1.2	0.9	1.1	-1.1
Area under the delay curve	0.1	0.2	0.3	0.5	0.2	-0.3
BMI with tail	1.2	3.8	4.5	-1.8	-2.1	1.9
BMI without tail	0.0	0.1	0.2	0.1	0.3	-0.4
Body weight	0.8	3.3	4.0	-2.0	-1.8	1.7
Weight adjusted by age	0.2	0.2	0.3	-0.4	-0.4	0.5
Bone surface	0.3	0.5	0.6	0.5	0.8	-0.7
Bone volume	0.1	0.1	0.2	0.2	0.4	-0.4
Breakpoint value in progressive ratio session	0.4	0.4	0.5	0.7	0.7	-0.6
Number of licking bursts	0.2	0.3	0.4	-0.3	-0.6	0.6
Context. condit. distance diff. score	0.1	0.1	0.2	0.1	0.4	-0.3
Locomotion velocity, session 1	2.7	2.9	3.2	1.6	1.8	-1.8
Locomotion distance, session 1	0.0	0.0	0.0	0.2	0.1	-0.1
Locomotion velocity, session 2	2.5	2.9	3.4	1.6	1.9	-1.7
Locomotion distance, session 2	0.5	0.6	0.7	-0.8	-0.8	0.7
Locomotion velocity, session 3	0.3	0.4	0.5	0.4	0.7	-0.7
Locomotion distance, session 3	0.1	0.1	0.1	-0.3	-0.3	0.3
Stereotopy head waving bouts, day 3	0.0	0.1	0.1	-0.2	-0.3	0.2
Stereotopy head waving duration, day 3	0.0	0.0	0.0	-0.1	0.1	-0.1
Locomotion velocity, session 7	0.0	0.0	0.1	-0.2	0.0	-0.3
Locomotion distance, session 7	0.1	0.1	0.3	-0.5	0.3	-0.2
Stereotopy head waving bouts, day 7	0.7	0.8	0.9	0.9	0.8	-0.9
Stereotopy head waving duration, day 7	1.2	1.4	1.6	1.3	1.1	-1.2
Locomotion velocity, session 8	1.5	1.8	2.3	1.1	1.4	-1.5
Locomotion distance, session 8	0.0	0.1	0.2	-0.4	-0.1	0.0
Degree of sensitization distance	0.1	0.1	0.4	-0.7	0.0	0.0
Degree of sensitization stereotypy	0.5	0.6	0.7	0.8	0.6	-0.8
Conditioned locomotion	0.1	0.2	0.3	-0.6	0.0	0.4
Cocaine response after cond. corrected	1.8	2.1	2.1	-1.4	-1.5	1.4
Cocaine response after cond. not corrected	2.8	3.1	3.3	-1.7	-1.7	1.8
Cocaine response before conditioning	0.1	0.2	0.3	-0.3	-0.4	0.5
Saline control response	0.0	0.0	0.1	0.1	-0.3	-0.0
Bone: connectivity density	1.1	1.7	2.1	1.1	1.4	-1.4
Bone: cortical apparent density	1.8	2.3	2.5	1.5	1.6	-1.5
Bone: cortical area	1.2	1.9	2.8	-1.7	-1.2	1.1
Bone: cortical porosity	0.0	0.0	0.0	-0.0	0.2	-0.0
Bone: cortical porosity	0.2	0.2	0.2	0.4	0.4	-0.5
Bone: cortical thickness	2.9	4.8	5.2	-2.3	-2.2	2.1
Bone: cortical thickness	1.7	2.0	2.1	-1.4	-1.5	1.3
Bone: cortical tissue density	1.9	2.5	2.7	1.5	1.7	-1.5
Condit. Reinf. active minus inactive responses	0.3	0.4	0.5	-0.5	-0.5	0.7
Condit. Reinf. active-inactive response ratio	0.6	0.7	0.7	-0.9	-0.9	0.8
Condit. Reinf. active responses	0.7	0.9	1.4	-0.7	-1.0	1.2
Condit. Reinf. inactive responses	0.1	0.1	0.1	0.3	-0.1	0.3
Incentive salience index mean	1.4	1.7	2.2	-1.2	-1.3	1.5
Condit. Reinf. lever presses	1.4	1.8	2.1	-1.3	-1.3	1.4
Condit. Reinf. active minus inactive responses	0.4	0.4	0.9	-0.9	-0.5	0.4
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.3	-0.6	-0.1	0.0
Condit. Reinf. active responses	0.4	0.5	0.9	-1.0	-0.5	0.6
Condit. Reinf. inactive responses	0.4	0.6	0.8	-0.6	-0.7	0.9
Condit. Reinf. lever presses	0.2	0.3	0.4	0.5	0.7	-0.4
Condit. Reinf. lever reinforcers received	0.3	0.4	0.7	-0.8	-0.5	0.5
Conditioned reinforcement - actives	2.4	2.4	2.5	-1.5	-1.5	1.6
Conditioned reinforcement - inactives	0.3	0.3	0.4	-0.7	-0.5	0.6
Conditioned locomotion	0.5	0.6	0.6	-0.7	-0.8	0.8
Patch foraging indifference point 0 sec	0.3	0.5	0.7	-0.8	-0.7	0.6
Patch foraging indifference point AUC	0.1	0.1	0.2	-0.1	0.4	-0.4
Delay disc. indifference point, 0s delay	0.6	0.7	0.8	0.9	0.8	-0.8
Delay disc. indifference point, 16s delay	1.0	1.0	1.3	-0.8	-1.1	1.1
Delay disc. indifference point, 2s delay	0.2	0.3	0.4	0.6	0.5	-0.4
Delay disc. indifference point, 24s delay	0.3	0.3	0.4	0.5	0.5	-0.6
Delay disc. indifference point, 4s delay	0.1	0.1	0.2	0.4	-0.0	-0.0
Delay disc. indifference point, 8s delay	0.1	0.1	0.1	0.3	0.1	-0.2
Indifference point function ln k	0.3	0.5	0.5	-0.7	-0.7	0.7
Indifference point function log k	0.3	0.5	0.5	-0.7	-0.7	0.7
Patch foraging total patch changes 0 sec	0.2	0.3	0.6	-0.7	-0.5	0.4
Patch foraging total patch changes 12 sec	1.3	1.7	2.3	1.1	1.5	-1.3
Patch foraging total patch changes 18 sec	0.3	0.3	0.5	-0.7	-0.6	0.5
Patch foraging total patch changes 24 sec	0.9	1.1	1.3	-1.1	-1.1	1.0
Patch foraging total patch changes 6 sec	0.1	0.2	0.5	-0.7	-0.2	0.2
Patch foraging time to switch 0 sec	2.0	3.2	5.2	2.3	1.5	-1.4
Patch foraging water rate 0 sec	2.5	4.0	5.3	-2.3	-1.9	1.8
Patch foraging water rate 12 sec	4.3	6.6	8.9	-3.0	-2.3	2.4
Patch foraging water rate 18 sec	0.0	0.0	0.0	-0.1	0.1	-0.0
Patch foraging water rate 24 sec	0.1	0.1	0.2	-0.5	-0.3	0.3
Patch foraging water rate 6 sec	1.4	2.1	2.1	-1.4	-1.5	1.4
Seeking ratio, delayed vs. immediate footshock	3.3	3.8	4.6	-2.1	-1.8	1.9
Distance traveled before self-admin	0.3	0.3	0.7	-0.8	-0.3	0.4
Distance traveled after self-admin	3.1	3.5	4.5	-2.1	-1.7	1.8
Extensor digitorum longus weight	1.3	4.9	6.3	-2.0	-2.5	2.1
Bone: elastic displacement	0.2	0.3	0.4	-0.7	-0.4	0.4
Bone: elastic work	0.3	0.4	0.8	-0.9	-0.4	0.5
Bone: endosteal estimation	0.1	0.2	0.4	0.1	0.5	-0.6
Bone: endosteal perimeter	0.3	0.6	0.9	0.4	0.8	-0.9
Epididymis fat weight	0.1	0.1	0.2	-0.1	0.4	-0.4
Delta time in closed arm before/after self-admin	0.8	0.8	1.7	-1.3	-0.6	0.6
Delta time in open arm before/after self-admin	0.2	0.2	0.5	0.7	0.3	-0.3
Diff in mean of infusions in LGA sessions	0.0	0.0	0.1	0.0	0.2	-0.2
Delay discount exponential model param	0.2	0.2	0.3	-0.6	-0.2	0.3
Extinction: sum of active levers before priming	0.0	0.0	0.1	0.3	0.1	-0.1
Active lever presses in extinction session 6	1.4	1.4	1.8	-1.4	-1.0	1.1
Bone: final force	0.0	0.0	0.0	-0.1	0.0	-0.1
Bone: final moment	0.0	0.0	0.1	-0.3	-0.1	0.0
Food consumed during 24 hour testing period	0.1	0.1	0.2	-0.4	-0.4	0.4
Glucose	0.0	0.1	0.1	0.2	-0.3	-0.1
Heart weight	1.2	1.8	1.9	-1.3	-1.4	1.3
Delay discount hyperbolic model param	0.2	0.2	0.4	-0.7	-0.3	0.4
Intermittent access intake day 1-15 change	1.8	1.8	1.9	-1.3	-1.4	1.4
Intermittent access intake escalation	1.5	1.5	1.6	-1.1	-1.2	1.3
Intermittent access intake escalation 2	0.1	0.1	0.1	-0.2	-0.3	0.3
Intermitt. access day 1 inactive lever presses	1.6	1.7	1.7	-1.3	-1.3	1.3
Intermitt. access day 15 inactive lever presses	0.3	0.4	0.5	-0.5	-0.7	0.7
Intermitt. access escalation Index	0.5	0.4	0.6	-0.6	-0.8	0.6
Intermittent access day 1 total infusions	0.1	0.1	0.1	-0.3	-0.3	0.3
Intermittent access day 15 total infusions	1.3	1.5	1.7	-1.2	-1.2	1.3
Intermittent access terminal intake (last 3 days)	0.4	0.4	0.5	-0.7	-0.6	0.6
Intermittent access total infusions	0.6	0.6	0.7	-0.8	-0.7	0.8
Intermittent access day 1 locomotion	0.4	0.4	0.6	-0.4	-0.8	0.8
Intermittent access day 15 total locomotion	0.1	0.1	0.2	0.1	-0.4	0.4
Intermittent access total locomotion	0.5	0.5	0.7	-0.5	-0.8	0.9
Intermittent access standard deviation	4.5	4.8	5.5	-1.9	-2.3	2.3
Left kidney weight	8.7	24.5	27.8	-5.3	-4.8	4.8
Right kidney weight	6.5	18.2	20.0	-4.5	-4.2	4.2
Cocaine induced anxiety	0.1	0.1	0.1	-0.1	-0.3	0.3
Post-drug Anxiety	0.3	0.3	0.5	0.7	0.5	-0.5
Baseline Anxiety	0.0	0.0	0.1	-0.2	-0.2	0.2
Tail length	0.6	1.8	2.5	0.9	1.6	-1.4
Length with tail	0.0	0.1	0.2	-0.4	0.3	-0.1
Length without tail	0.9	1.9	2.0	-1.4	-1.4	1.4
Times rat made contact with spout	0.1	0.1	0.2	-0.3	-0.5	0.3
Lifetime Intake	0.6	0.7	0.8	-0.9	-0.8	0.9
Liver weight, left	0.4	0.6	1.2	-1.1	-0.6	0.6
Liver weight, right	0.0	0.0	0.1	-0.3	-0.1	-0.0
Locomotor activity	0.0	0.0	0.0	0.2	0.2	0.0
Locomotor testing distance	0.1	0.2	0.2	-0.5	-0.3	0.5
Locomotor testing rearing	0.0	0.0	0.1	-0.0	-0.3	0.2
Locomotion in novel chamber	2.1	2.6	2.8	-1.7	-1.5	1.7
Locomotion in novel chamber post-restriction	0.3	0.3	0.4	-0.6	-0.5	0.6
Fecal boli incidents, locomotor time 1	0.0	0.0	0.0	0.0	-0.0	-0.1
Change in fecal boli incidents, locomotor task	0.9	0.8	0.9	1.0	0.9	-0.8
Time >=10cm from walls, locomotor time 1	0.6	0.6	0.8	0.3	0.9	-0.9
Bouts of movement, locomotor time 1	0.9	1.0	1.1	1.0	0.9	-1.0
Total resting periods, locomotor time 1	0.7	0.8	0.9	1.0	0.8	-0.9
Rest time, locomotor task time 1	0.2	0.2	0.3	0.5	0.4	-0.5
Distance moved, locomotor task time 1	0.1	0.1	0.1	-0.3	0.3	-0.1
Vertical activity count, locomotor time 1	0.4	0.5	0.7	-0.8	-0.5	0.7
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.4	-0.7	-0.2	0.2
Bouts of movement, locomotor time 2	0.4	0.4	0.5	0.6	0.7	-0.7
Total resting periods, locomotor time 2	0.5	0.5	0.5	0.7	0.7	-0.7
Rest time, locomotor task time 2	0.3	0.3	0.6	0.8	0.3	-0.4
Distance moved, locomotor task time 2	1.3	1.5	2.7	-1.6	-0.8	1.0
Vertical activity count, locomotor time 2	2.1	2.3	3.4	-1.8	-1.2	1.3
Light reinforcement 1	0.1	0.2	0.4	-0.4	-0.4	0.6
Light reinforcement 2	1.4	1.9	2.5	-1.6	-1.2	1.4
Bone: marrow area	0.1	0.2	0.3	-0.0	0.4	-0.5
Bone: maximum diameter	0.1	0.1	0.4	-0.6	-0.2	0.2
Bone: maximum force	0.0	0.0	0.1	-0.3	-0.1	-0.0
Bone: maximum moment	0.1	0.1	0.3	-0.5	-0.2	0.1
Mean time between licks in bursts	1.4	2.0	2.4	1.5	1.4	-1.3
Mean num. licks in bursts	0.1	0.1	0.1	-0.3	-0.4	0.1
Cd content in liver	0.1	0.2	0.3	0.3	0.4	-0.5
Co content in liver	0.6	0.7	0.9	0.7	0.8	-0.9
Cu content in liver	0.0	0.1	0.1	0.1	0.3	-0.3
Fe content in liver	1.0	1.2	1.4	-1.1	-1.2	1.1
K content in liver	1.3	1.3	1.8	1.0	1.3	-1.1
Mg content in liver	0.0	0.0	0.1	-0.1	-0.2	0.1
Mn content in liver	0.0	0.0	0.1	-0.2	0.2	-0.0
Na content in liver	0.9	0.9	1.4	0.7	1.2	-1.0
Rb content in liver	0.0	0.0	0.1	0.1	-0.3	-0.1
Se content in liver	0.2	0.2	0.4	-0.1	0.6	-0.5
Sr content in liver	0.0	0.0	0.0	-0.1	0.1	0.0
Zn content in liver	0.2	0.2	0.3	0.5	0.3	-0.5
Bone: minimum diameter	0.3	0.5	1.3	-1.1	-0.5	0.4
Time in familiar zone, hab. session 1	0.2	0.2	0.3	0.1	0.6	-0.6
Time in novel zone, hab. session 1	0.1	0.1	0.1	0.3	0.2	-0.3
Total zone transitions, hab. session 1	0.0	0.0	0.0	0.2	0.1	-0.2
Total locomotion distance, hab. session 1	0.3	0.5	0.6	-0.6	-0.8	0.7
Locomotion velocity, hab. session 1	0.1	0.2	0.3	-0.3	-0.6	0.5
Time in familiar zone, hab. session 2	0.6	0.6	0.8	0.5	0.9	-0.9
Time in novel zone, hab. session 2	0.2	0.2	0.2	-0.3	-0.5	0.4
Total zone transitions, hab. session 2	0.0	0.0	0.0	0.0	-0.0	-0.0
Total locomotion distance, hab. session 2	0.3	0.4	0.5	-0.6	-0.7	0.7
Locomotion velocity, hab. session 2	0.5	0.6	0.7	-0.8	-0.8	0.8
Novel to familiar place preference ratio	1.0	1.0	1.1	-1.0	-1.0	1.0
Novelty place preference	0.5	0.5	0.6	-0.7	-0.7	0.7
Time in novel zone, NPP test	0.3	0.3	0.4	-0.6	-0.6	0.6
Total zone transitions, NPP test	0.7	1.0	1.0	-1.0	-1.0	1.0
Total locomotion distance, NPP test	1.0	1.3	1.4	-1.1	-1.2	1.2
Locomotion velocity, NPP test	1.6	2.3	2.3	-1.5	-1.5	1.5
Intraocular pressure	0.3	0.4	0.5	-0.6	-0.7	0.5
Delta distance traveled before/after self-admin	3.3	3.5	4.0	-1.6	-2.0	2.0
Delta ambulatory time before/after self-admin	2.4	2.6	3.0	-1.4	-1.7	1.7
Parametrial fat weight	0.1	0.2	0.3	0.4	0.5	-0.4
Pavlov. Cond. lever latency	2.1	2.7	2.9	1.7	1.5	-1.7
Pavlov. Cond. magazine entry latency	0.4	0.5	0.6	0.8	0.7	-0.6
Pavlov. Cond. change in total contacts	0.0	0.0	0.0	0.0	0.1	0.0
Pavlov. Cond. index score	0.3	0.4	0.5	-0.7	-0.5	0.7
Pavlov. Cond. latency score	0.4	0.5	0.7	-0.8	-0.6	0.8
Pavlov. Cond. lever contacts	1.6	1.9	2.2	-1.4	-1.3	1.5
Pavlov. Cond. magazine entry number	0.3	0.3	0.4	-0.6	-0.7	0.4
Pavlov. Cond. intertrial magazine entries	0.5	0.6	0.7	-0.6	-0.8	0.8
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.4	0.5	-0.7	-0.5	0.7
Pavlov. Cond. response bias	0.1	0.1	0.1	-0.3	-0.1	0.3
Pavlov. Cond. lever latency	0.1	0.2	0.2	-0.5	-0.4	0.3
Pavlov. Cond. magazine entry latency	1.6	1.9	2.1	1.4	1.3	-1.4
Pavlov. Cond. change in total contacts	0.2	0.3	0.3	0.6	0.6	-0.5
Pavlov. Cond. index score	0.8	1.0	1.2	1.1	1.0	-1.0
Pavlov. Cond. latency score	0.6	0.7	0.8	0.9	0.8	-0.9
Pavlov. Cond. lever contacts	0.1	0.1	0.1	0.3	0.3	-0.2
Pavlov. Cond. magazine entry number	2.4	2.9	3.3	-1.7	-1.6	1.8
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	0.5	-0.0	0.3
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.2	1.4	1.2	1.0	-1.1
Pavlov. Cond. response bias	0.6	0.9	0.9	1.0	0.9	-0.9
Time in closed arm before self-admin	0.9	1.0	1.5	1.2	0.8	-0.9
Time in closed arm after self-admin	0.0	0.0	0.0	0.0	-0.1	-0.0
Time in open arm before self-admin	0.0	0.0	0.1	-0.2	0.2	-0.2
Time in open arm after self-admin	0.0	0.0	0.0	-0.1	-0.0	0.1
Bone: periosteal estimation	0.3	0.6	1.3	-1.1	-0.5	0.5
Bone: periosteal perimeter	0.1	0.1	0.3	-0.5	0.0	-0.1
Bone: post-yield work	0.2	0.2	0.3	0.5	0.5	-0.4
Progressive ratio test 1 active lever presses	0.2	0.2	0.2	-0.4	-0.4	0.5
Progressive ratio test 1 breakpoint	0.4	0.4	0.4	-0.6	-0.6	0.6
Progressive ratio test 1 inactive lever presses	0.7	0.8	0.9	-1.0	-0.8	0.8
Progressive ratio test 2 active lever presses	1.1	1.2	1.4	-1.2	-1.0	1.1
Progressive ratio test 2 breakpoint	1.2	1.3	1.6	-1.3	-1.1	1.1
Progressive ratio test 2 inactive lever presses	1.2	1.4	1.4	-1.2	-1.2	1.2
Incentive Sensitization - Responses	0.1	0.1	0.1	-0.4	-0.3	0.3
Incentive Sensitization - Breakpoint	0.2	0.2	0.3	-0.5	-0.4	0.4
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	0.1	0.3	-0.2
Progressive ratio	0.1	0.1	0.2	-0.1	-0.4	0.4
Food seeking constrained by brief footshock	3.4	4.2	4.5	2.0	2.1	-2.1
Seeking ratio, punishment vs. effort	2.6	3.2	3.7	1.5	1.9	-1.9
Retroperitoneal fat weight	0.0	0.2	0.3	0.1	0.5	-0.4
Reaction time number correct	0.0	0.0	0.0	-0.2	-0.1	-0.0
Reaction time mean minus median	0.3	0.4	0.5	0.6	0.6	-0.7
Reaction time mean minus median AUC	0.2	0.3	0.4	0.4	0.6	-0.6
Reaction time num false alarms	0.8	1.1	1.3	-0.9	-1.0	1.2
Reaction time num false alarms AUC	1.4	2.0	2.2	-1.3	-1.4	1.5
Reaction time trials correct on left	0.0	0.0	0.0	-0.2	-0.1	-0.0
Reaction time trials on left	0.0	0.0	0.0	-0.1	-0.1	-0.1
Reaction time mean	0.7	0.9	1.4	1.2	0.9	-0.8
Reaction time mean AUC	0.9	1.1	1.5	1.2	1.0	-0.9
Median of all reaction times	0.9	1.3	2.1	1.4	1.0	-0.8
Reaction time omissions	0.3	0.4	0.7	0.8	0.4	-0.5
Reaction time false alarm rate	1.4	1.9	2.4	-1.3	-1.3	1.5
Reaction time premature initiation rate	0.4	0.6	0.8	0.8	0.9	-0.5
Reaction time premature initiations	0.4	0.6	0.8	0.8	0.9	-0.6
Std. dev. reaction times	0.2	0.2	0.3	0.4	0.5	-0.5
Reaction time trials completed	0.0	0.0	0.0	-0.1	-0.1	-0.1
Reaction time trials AUC	0.1	0.1	0.1	-0.3	-0.3	0.2
Run reversals in cocaine runway, females	0.6	0.6	0.9	1.0	0.7	-0.6
Run reversals in cocaine runway, males	2.3	2.2	2.6	-1.6	-1.5	1.4
Latency to leave start box in cocaine runway	1.1	1.2	1.4	-1.2	-1.1	1.1
Latency to leave start box in cocaine runway, F	1.7	1.8	2.3	-1.5	-1.3	1.3
Latency to leave start box in cocaine runway, M	0.0	0.0	0.0	-0.1	-0.1	0.1
Std. dev. time between licks in bursts	2.8	3.3	3.5	1.8	1.9	-1.8
Total sessions with >9 infusions	0.1	0.1	0.2	0.3	0.4	-0.3
Short access day 1 total inactive lever presses	5.2	5.8	6.4	-2.5	-2.3	2.3
Short access day 10 total inactive lever presses	1.8	2.0	2.1	-1.5	-1.4	1.3
Short access day 1 total infusions	0.3	0.3	0.3	-0.6	-0.6	0.6
Short access day 10 total infusions	0.6	0.6	0.7	-0.7	-0.8	0.8
Short access total infusions	0.7	0.8	0.9	-0.8	-0.9	0.9
Short access day 1 locomotion	1.6	1.7	1.8	-1.2	-1.4	1.3
Short access day 10 total locomotion	1.0	1.2	1.5	-0.8	-1.2	1.2
Short access total locomotion	0.2	0.2	0.3	-0.3	-0.5	0.5
One hour access (0.3 mA shock)	0.1	0.2	0.2	0.5	0.4	-0.4
Compulsive drug intake	0.3	0.3	0.4	0.7	0.4	-0.6
One hour access (shock baseline)	0.3	0.3	0.4	-0.6	-0.5	0.6
Social response proportion	0.6	0.7	0.8	0.9	0.8	-0.7
Social responses	2.1	2.7	3.1	1.8	1.6	-1.6
Social time	0.0	0.0	0.1	-0.0	-0.2	0.3
Soleus weight	2.7	8.0	9.0	-2.8	-3.0	2.7
Bone: stiffness	0.0	0.0	0.0	0.0	0.1	-0.2
Tibialis anterior weight	4.4	15.2	16.2	-3.8	-4.0	3.9
Time to tail flick, vehicle, before self-admin	1.2	1.2	1.4	-1.0	-1.2	1.1
Time to tail flick, vehicle, after self-admin	0.7	0.8	1.1	-0.5	-1.1	0.9
Time to tail flick, test, before self-admin	1.8	1.7	2.1	-1.1	-1.4	1.4
Time to tail flick, test, after self-admin	1.3	1.4	1.5	-1.0	-1.2	1.2
Delta time to tail flick, vehicle, before/after SA	0.0	0.0	0.1	-0.2	-0.2	0.2
Delta time to tail flick, test, before/after SA	0.1	0.1	0.1	0.3	0.4	-0.3
Tibia length	0.1	0.3	0.5	-0.4	-0.3	0.7
Ambulatory time before self-admin	0.4	0.4	0.9	-0.9	-0.3	0.3
Ambulatory time after self-admin	2.5	2.7	3.0	-1.7	-1.6	1.6
Bone: tissue strength	0.6	0.6	0.8	0.6	0.9	-0.7
Total heroin consumption	2.6	3.0	3.9	2.0	1.6	-1.6
Bone: trabecular number	0.9	1.4	1.4	1.2	1.2	-1.2
Bone: trabecular spacing	1.5	1.9	2.6	-1.0	-1.6	1.5
Bone: trabecular thickness	1.3	1.5	2.1	0.9	1.4	-1.3
Bone: trabecular tissue density	0.1	0.2	0.3	0.3	0.6	-0.4
Water consumed over 24 hours	0.5	0.6	1.0	-1.0	-0.7	0.6
Number of responses in last shaping day	2.4	2.5	2.6	-1.6	-1.6	1.5