Sez6

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Sez6 0.23 0.23 0.0e+00 0.14 0.16 0.17 0.17 4.1e-21 3.7e-23 4.0e-25 4.7e-25
2 Brain gene expression Sez6 0.45 0.25 0.0e+00 0.37 0.4 0.4 0.4 7.1e-36 4.3e-39 3.2e-39 3.0e-39
3 PL gene expression Sez6 0.11 0.1 2.4e-11 0.09 0.1 0.1 0.1 2.4e-10 1.7e-11 2.7e-11 3.7e-11
4 IL gene expression Sez6 0.16 0.15 1.4e-03 0.11 0.12 0.1 0.1 1.6e-03 8.3e-04 1.7e-03 1.8e-03
5 NAcc mRNA stability Sez6 0.03 0.03 2.6e-05 0.02 0.03 0.03 0.03 1.5e-04 1.8e-05 2.4e-05 2.5e-05
6 pVTA gene expression Sez6 0.09 0.08 2.4e-07 0.07 0.09 0.08 0.08 2.3e-06 2.0e-07 9.2e-07 8.1e-07
7 RMTg gene expression Sez6 0.1 0.1 6.9e-03 0.06 0.09 0.07 0.06 8.6e-03 2.5e-03 6.2e-03 9.3e-03
8 Liver gene expression Sez6 0.52 0.19 0.0e+00 0.41 0.43 0.44 0.44 8.4e-49 1.2e-52 3.9e-53 5.7e-53
9 BLA gene expression Sez6 0.29 0.2 1.4e-11 0.12 0.17 0.15 0.18 3.7e-07 2.1e-09 1.7e-08 1.2e-09
10 Liver mRNA stability Sez6 0.04 0.04 1.1e-04 0.03 0.03 0.02 0.03 5.2e-04 5.3e-04 2.1e-03 8.3e-04
11 Brain mRNA stability Sez6 0.28 0.2 0.0e+00 0.24 0.26 0.25 0.26 2.9e-22 1.2e-24 1.4e-23 2.6e-24
12 IC intron excision ratio chr10_63365555_63365712 0.08 0.08 4.3e-03 0.05 0.02 0.03 0.02 4.8e-03 5.5e-02 1.7e-02 4.1e-02
13 NAcc intron excision ratio chr10_63364752_63364971 0.04 0.04 1.6e-05 0.03 0.03 0.03 0.03 1.1e-05 2.9e-05 1.2e-05 1.5e-05
14 LHb gene expression Sez6 0.56 0.25 9.7e-12 0.33 0.44 0.38 0.44 1.0e-08 9.9e-12 4.3e-10 9.4e-12
15 pVTA mRNA stability Sez6 0.03 0.03 4.9e-03 0.03 0.02 0.02 0.02 3.6e-03 7.8e-03 1.8e-02 1.1e-02
16 PL mRNA stability Sez6 0.04 0.04 1.0e-04 0.03 0.04 0.04 0.04 1.1e-04 8.6e-05 4.8e-05 7.7e-05
17 IC gene expression Sez6 0.08 0.08 3.5e-03 0.06 0.05 0.07 0.05 1.5e-03 3.8e-03 6.0e-04 4.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density2.24.04.31.9-2.0-2.0-2.02.0-2.0-2.02.1-2.02.02.0-2.0-2.0-1.9-2.1-2.1-2.1
Area under the delay curve2.03.13.9-1.51.81.71.8-1.81.81.8-1.81.7-2.0-1.81.71.61.71.81.81.9
BMI with tail1.65.76.32.5-2.4-2.4-2.42.4-2.4-2.42.4-2.32.52.3-2.3-2.5-2.2-2.5-2.3-2.3
BMI without tail1.26.47.02.6-2.5-2.6-2.62.6-2.6-2.62.6-2.62.62.6-2.5-2.6-2.5-2.3-2.4-2.3
Body weight2.410.512.03.5-3.2-3.3-3.33.3-3.3-3.33.3-3.33.23.3-3.2-3.3-3.2-3.4-2.9-2.6
Weight adjusted by age0.10.30.70.4-0.6-0.5-0.50.5-0.5-0.50.4-0.50.20.5-0.5-0.5-0.5-0.0-0.8-0.7
Bone surface1.63.13.51.7-1.8-1.7-1.71.7-1.7-1.71.8-1.81.71.7-1.7-1.8-1.7-1.8-1.8-1.9
Bone volume1.32.62.81.6-1.6-1.6-1.61.6-1.6-1.61.7-1.61.61.6-1.6-1.6-1.6-1.7-1.7-1.7
Breakpoint value in progressive ratio session0.50.81.20.7-1.0-1.0-1.01.0-1.0-1.00.9-1.00.81.0-1.0-1.0-1.1-0.8-0.7-0.5
Number of licking bursts0.10.40.6-0.70.60.60.6-0.60.60.6-0.70.6-0.6-0.60.50.60.50.70.60.6
Context. condit. distance diff. score0.60.70.80.9-0.8-0.8-0.80.8-0.8-0.80.9-0.80.80.8-0.8-0.8-0.8-0.8-0.8-0.8
Locomotion velocity, session 12.02.22.61.5-1.5-1.5-1.51.5-1.5-1.51.5-1.51.51.5-1.5-1.5-1.6-1.5-1.3-1.2
Locomotion distance, session 10.20.20.40.5-0.5-0.5-0.50.5-0.5-0.50.5-0.50.30.5-0.5-0.5-0.6-0.5-0.3-0.0
Locomotion velocity, session 20.00.10.10.2-0.2-0.2-0.20.2-0.2-0.20.2-0.20.20.3-0.2-0.2-0.3-0.2-0.2-0.1
Locomotion distance, session 21.21.72.21.3-1.3-1.3-1.31.3-1.3-1.31.2-1.31.21.3-1.3-1.3-1.4-1.3-1.5-1.5
Locomotion velocity, session 33.03.44.0-2.01.81.91.9-1.91.91.9-1.91.9-1.7-1.91.91.91.91.91.71.5
Locomotion distance, session 30.40.50.6-0.70.70.70.7-0.70.70.7-0.80.7-0.6-0.70.70.70.70.70.80.8
Stereotopy head waving bouts, day 30.00.00.20.1-0.2-0.2-0.20.2-0.2-0.20.2-0.20.20.2-0.2-0.2-0.2-0.3-0.3-0.4
Stereotopy head waving duration, day 30.20.30.6-0.80.50.60.6-0.60.60.6-0.50.5-0.4-0.50.50.50.50.60.30.2
Locomotion velocity, session 70.40.50.60.5-0.7-0.7-0.70.7-0.7-0.70.7-0.70.80.7-0.7-0.7-0.7-0.7-0.7-0.6
Locomotion distance, session 70.50.70.80.8-0.8-0.8-0.90.9-0.9-0.80.8-0.80.90.9-0.8-0.8-0.9-0.7-0.8-0.7
Stereotopy head waving bouts, day 70.60.71.20.8-0.8-0.8-0.80.8-0.8-0.80.8-0.80.80.8-0.8-0.8-0.8-0.9-1.0-1.1
Stereotopy head waving duration, day 70.30.40.80.5-0.7-0.6-0.60.6-0.6-0.60.6-0.60.60.6-0.6-0.6-0.6-0.7-0.8-0.9
Locomotion velocity, session 80.00.00.00.1-0.1-0.1-0.10.1-0.1-0.10.1-0.10.20.1-0.1-0.1-0.2-0.2-0.1-0.1
Locomotion distance, session 80.81.21.31.1-1.1-1.1-1.11.1-1.1-1.11.1-1.11.01.1-1.1-1.1-1.1-1.1-1.1-1.1
Degree of sensitization distance3.33.53.71.8-1.9-1.9-1.91.9-1.9-1.91.9-1.91.81.9-1.9-1.9-1.9-1.8-1.8-1.7
Degree of sensitization stereotypy0.70.71.20.8-0.9-0.8-0.80.8-0.8-0.80.8-0.80.80.8-0.8-0.8-0.8-0.8-1.0-1.1
Conditioned locomotion1.31.52.0-1.41.21.31.3-1.21.21.3-1.21.3-1.0-1.21.21.31.21.41.10.9
Cocaine response after cond. corrected1.31.92.21.3-1.4-1.4-1.41.4-1.4-1.41.4-1.31.51.4-1.4-1.4-1.4-1.3-1.4-1.5
Cocaine response after cond. not corrected1.82.62.81.5-1.6-1.6-1.61.6-1.6-1.61.6-1.61.71.6-1.6-1.6-1.6-1.5-1.6-1.7
Cocaine response before conditioning0.20.20.40.4-0.5-0.5-0.50.5-0.5-0.50.4-0.60.40.5-0.5-0.5-0.5-0.5-0.5-0.3
Saline control response0.00.00.0-0.1-0.10.00.0-0.00.00.0-0.0-0.10.0-0.00.1-0.10.10.0-0.0-0.1
Bone: connectivity density4.06.47.12.4-2.6-2.5-2.52.5-2.5-2.52.6-2.62.52.5-2.5-2.6-2.4-2.6-2.6-2.7
Bone: cortical apparent density0.30.50.6-0.80.70.70.7-0.70.70.7-0.70.7-0.5-0.70.70.70.60.80.60.5
Bone: cortical area1.42.32.6-1.41.61.51.5-1.51.51.5-1.41.6-1.5-1.51.51.61.51.51.51.5
Bone: cortical porosity0.30.30.50.5-0.6-0.6-0.60.6-0.6-0.60.6-0.60.70.6-0.5-0.7-0.6-0.7-0.5-0.5
Bone: cortical porosity0.10.10.20.3-0.4-0.4-0.40.4-0.4-0.40.4-0.40.40.3-0.3-0.5-0.3-0.5-0.3-0.4
Bone: cortical thickness2.64.34.8-2.12.12.12.1-2.12.12.1-2.02.2-2.0-2.12.02.22.02.02.02.0
Bone: cortical thickness0.00.00.0-0.20.10.10.1-0.10.10.1-0.00.1-0.2-0.10.10.10.10.20.10.1
Bone: cortical tissue density0.10.20.3-0.60.50.50.5-0.50.50.5-0.50.5-0.3-0.50.50.50.50.50.40.3
Condit. Reinf. active minus inactive responses0.60.70.9-0.90.80.80.8-0.80.80.8-0.90.8-0.8-0.80.80.80.80.90.70.7
Condit. Reinf. active-inactive response ratio0.10.20.2-0.40.40.40.4-0.40.40.4-0.40.4-0.4-0.40.40.40.40.40.30.3
Condit. Reinf. active responses0.00.00.0-0.20.10.10.1-0.10.10.1-0.20.1-0.1-0.10.10.10.10.10.0-0.0
Condit. Reinf. inactive responses0.30.40.50.5-0.6-0.6-0.60.6-0.6-0.60.5-0.60.60.6-0.6-0.6-0.7-0.7-0.7-0.7
Incentive salience index mean0.20.30.4-0.60.50.60.6-0.60.60.6-0.60.6-0.5-0.50.60.60.50.50.30.2
Condit. Reinf. lever presses0.10.20.50.3-0.4-0.3-0.30.3-0.3-0.30.3-0.30.40.3-0.3-0.3-0.3-0.5-0.6-0.7
Condit. Reinf. active minus inactive responses0.10.20.5-0.70.40.50.5-0.50.50.5-0.40.4-0.4-0.40.50.50.50.70.40.3
Condit. Reinf. active-inactive response ratio0.30.50.7-0.80.70.70.7-0.70.70.7-0.70.7-0.6-0.70.80.80.80.80.60.5
Condit. Reinf. active responses0.10.10.3-0.50.30.30.3-0.30.30.3-0.30.3-0.3-0.30.30.40.30.50.20.2
Condit. Reinf. inactive responses0.10.10.20.1-0.3-0.3-0.30.3-0.3-0.30.3-0.30.20.3-0.4-0.2-0.4-0.1-0.3-0.2
Condit. Reinf. lever presses2.23.33.6-1.91.81.81.8-1.81.81.8-1.81.8-1.8-1.81.91.81.81.81.71.7
Condit. Reinf. lever reinforcers received0.30.40.6-0.80.60.60.6-0.60.60.6-0.60.6-0.6-0.60.60.70.60.80.50.5
Conditioned reinforcement - actives0.10.30.60.6-0.5-0.5-0.50.5-0.5-0.50.6-0.70.60.5-0.5-0.7-0.5-0.8-0.6-0.7
Conditioned reinforcement - inactives0.00.10.20.5-0.2-0.3-0.30.3-0.3-0.30.3-0.30.20.3-0.3-0.1-0.3-0.4-0.10.0
Conditioned locomotion0.10.20.60.6-0.5-0.4-0.40.4-0.4-0.40.4-0.50.50.3-0.3-0.3-0.3-0.7-0.5-0.8
Patch foraging indifference point 0 sec0.20.61.0-0.80.80.70.7-0.70.70.7-0.80.8-0.9-0.70.70.80.70.80.81.0
Patch foraging indifference point AUC1.22.73.2-1.81.71.71.7-1.71.71.7-1.61.7-1.4-1.71.81.71.81.61.41.0
Delay disc. indifference point, 0s delay1.11.21.6-0.91.11.11.1-1.11.11.1-1.21.1-1.3-1.11.11.01.11.01.01.1
Delay disc. indifference point, 16s delay1.72.33.4-1.21.61.51.5-1.61.51.5-1.61.5-1.8-1.61.51.41.51.61.41.5
Delay disc. indifference point, 2s delay2.93.24.3-1.91.91.81.8-1.81.81.8-1.81.7-2.1-1.81.71.61.71.71.81.9
Delay disc. indifference point, 24s delay0.40.60.70.8-0.8-0.8-0.80.8-0.8-0.80.8-0.80.80.8-0.8-0.8-0.8-0.8-0.8-0.8
Delay disc. indifference point, 4s delay0.50.51.8-0.50.70.60.6-0.60.60.6-0.70.5-0.8-0.60.60.80.60.81.11.3
Delay disc. indifference point, 8s delay0.91.52.2-1.11.31.31.3-1.31.31.3-1.21.2-1.3-1.31.31.11.31.51.00.9
Indifference point function ln k0.30.81.01.0-0.9-1.0-1.01.0-1.0-1.00.8-1.00.51.0-1.0-1.0-1.0-0.9-0.5-0.1
Indifference point function log k0.30.81.01.0-0.9-1.0-1.01.0-1.0-1.00.8-1.00.51.0-1.0-1.0-1.0-0.9-0.5-0.1
Patch foraging total patch changes 0 sec0.10.40.7-0.70.70.60.6-0.60.60.6-0.60.7-0.8-0.60.60.70.50.70.70.9
Patch foraging total patch changes 12 sec0.20.30.4-0.50.60.50.5-0.50.50.5-0.50.6-0.6-0.50.50.50.60.40.40.4
Patch foraging total patch changes 18 sec0.92.12.8-1.51.51.41.4-1.41.41.4-1.41.5-1.4-1.41.41.51.41.71.31.4
Patch foraging total patch changes 24 sec0.82.73.3-1.81.61.71.7-1.71.71.7-1.61.7-1.5-1.61.71.71.71.81.41.3
Patch foraging total patch changes 6 sec2.94.95.5-2.22.32.32.3-2.32.32.3-2.22.3-2.1-2.32.32.32.32.02.01.8
Patch foraging time to switch 0 sec0.62.42.71.6-1.6-1.5-1.51.5-1.5-1.51.5-1.51.61.5-1.5-1.5-1.6-1.5-1.6-1.6
Patch foraging water rate 0 sec0.82.93.5-1.71.81.71.7-1.71.71.7-1.61.6-1.9-1.71.71.61.71.81.81.9
Patch foraging water rate 12 sec0.10.30.40.6-0.5-0.6-0.60.6-0.6-0.60.6-0.60.30.6-0.6-0.6-0.6-0.5-0.5-0.2
Patch foraging water rate 18 sec0.30.60.80.9-0.8-0.8-0.80.8-0.8-0.80.9-0.80.60.8-0.8-0.8-0.7-0.7-0.7-0.6
Patch foraging water rate 24 sec0.20.30.7-0.40.60.50.5-0.50.50.5-0.50.5-0.8-0.50.50.50.50.60.70.9
Patch foraging water rate 6 sec1.01.52.2-1.21.21.21.2-1.11.11.2-1.11.2-1.4-1.11.11.11.21.31.31.5
Seeking ratio, delayed vs. immediate footshock1.72.43.6-1.41.51.61.6-1.61.61.6-1.61.6-1.4-1.71.61.91.61.41.00.8
Distance traveled before self-admin1.84.04.6-2.12.12.12.1-2.12.12.1-2.12.2-1.8-2.12.22.12.10.91.71.3
Distance traveled after self-admin0.10.10.1-0.30.30.30.3-0.40.40.3-0.30.4-0.1-0.40.40.30.30.10.0-0.2
Extensor digitorum longus weight0.72.83.21.7-1.7-1.7-1.71.7-1.7-1.71.8-1.71.61.7-1.7-1.7-1.7-1.6-1.8-1.8
Bone: elastic displacement2.83.53.7-1.91.91.91.9-1.91.91.9-1.81.8-1.9-1.91.91.91.91.81.91.9
Bone: elastic work8.411.012.6-3.33.43.33.3-3.33.33.3-3.23.3-3.3-3.23.23.43.33.33.43.5
Bone: endosteal estimation0.00.10.2-0.10.20.20.2-0.20.20.2-0.20.0-0.4-0.20.20.20.30.10.40.5
Bone: endosteal perimeter0.00.00.00.10.00.00.0-0.00.00.00.0-0.0-0.1-0.00.00.10.10.00.10.2
Epididymis fat weight5.025.529.05.4-5.2-5.1-5.15.1-5.1-5.15.1-5.14.95.1-5.0-5.0-5.0-5.1-4.7-4.5
Delta time in closed arm before/after self-admin3.02.83.0-1.71.71.61.6-1.61.61.6-1.71.6-1.7-1.61.61.61.71.71.71.7
Delta time in open arm before/after self-admin5.05.98.02.6-2.4-2.4-2.42.4-2.3-2.42.4-2.32.52.3-2.3-2.3-2.3-2.2-2.7-2.8
Diff in mean of infusions in LGA sessions0.40.70.70.8-0.8-0.8-0.80.8-0.8-0.80.7-0.80.80.8-0.8-0.9-0.8-0.8-0.8-0.7
Delay discount exponential model param1.62.12.61.3-1.5-1.4-1.41.4-1.4-1.41.5-1.41.61.4-1.4-1.3-1.4-1.5-1.5-1.6
Extinction: sum of active levers before priming0.81.21.31.0-1.1-1.1-1.11.1-1.1-1.11.1-1.21.11.2-1.2-1.1-1.1-1.1-0.9-0.9
Active lever presses in extinction session 60.50.50.70.5-0.7-0.7-0.80.8-0.8-0.80.8-0.80.60.8-0.8-0.9-0.8-0.8-0.6-0.5
Bone: final force0.40.60.7-0.70.80.80.8-0.80.80.8-0.70.8-0.8-0.80.80.80.70.70.80.9
Bone: final moment0.40.70.9-0.70.90.80.8-0.80.80.8-0.80.8-0.9-0.80.80.80.80.70.90.9
Food consumed during 24 hour testing period0.10.20.6-0.50.40.30.3-0.30.30.3-0.30.3-0.6-0.30.30.30.30.60.60.8
Glucose1.42.32.8-1.61.51.61.6-1.61.61.6-1.41.5-1.4-1.61.61.51.71.51.41.2
Heart weight1.62.63.11.6-1.6-1.7-1.71.7-1.7-1.71.7-1.71.41.7-1.8-1.6-1.7-1.4-1.5-1.2
Delay discount hyperbolic model param2.12.73.41.5-1.7-1.6-1.61.6-1.6-1.61.6-1.51.81.6-1.6-1.5-1.6-1.7-1.7-1.8
Intermittent access intake day 1-15 change0.00.10.40.1-0.3-0.2-0.20.2-0.2-0.20.3-0.40.30.2-0.1-0.3-0.1-0.2-0.3-0.6
Intermittent access intake escalation0.00.10.60.3-0.4-0.3-0.30.3-0.3-0.30.4-0.50.50.3-0.2-0.4-0.2-0.3-0.4-0.7
Intermittent access intake escalation 20.10.20.3-0.50.40.40.5-0.50.50.4-0.40.3-0.2-0.50.50.40.50.40.3-0.1
Intermitt. access day 1 inactive lever presses0.00.20.3-0.40.40.40.4-0.40.40.4-0.40.4-0.5-0.40.40.50.40.50.40.4
Intermitt. access day 15 inactive lever presses0.10.60.7-0.80.80.80.8-0.80.80.8-0.80.7-0.8-0.80.80.80.80.80.80.8
Intermitt. access escalation Index0.30.81.61.0-0.9-0.9-0.90.9-0.9-0.90.8-0.90.70.9-0.9-1.1-0.9-1.3-0.9-0.8
Intermittent access day 1 total infusions0.00.10.20.4-0.2-0.2-0.20.2-0.2-0.20.2-0.30.10.2-0.2-0.3-0.2-0.3-0.2-0.1
Intermittent access day 15 total infusions0.40.91.71.0-1.0-0.9-0.90.9-0.9-0.90.9-1.10.90.9-0.8-0.9-0.8-1.1-1.1-1.3
Intermittent access terminal intake (last 3 days)0.61.01.51.1-0.9-1.0-0.90.9-0.9-1.01.0-1.10.90.9-0.9-1.0-0.9-1.2-1.0-1.2
Intermittent access total infusions0.20.31.10.6-0.5-0.4-0.40.4-0.4-0.40.5-0.50.50.4-0.3-0.5-0.3-0.7-0.7-1.0
Intermittent access day 1 locomotion0.00.00.10.1-0.00.00.0-0.00.00.0-0.0-0.00.0-0.00.00.00.0-0.1-0.1-0.3
Intermittent access day 15 total locomotion0.10.40.70.7-0.6-0.6-0.60.6-0.6-0.60.6-0.80.70.6-0.5-0.7-0.5-0.7-0.6-0.8
Intermittent access total locomotion0.40.51.10.7-0.7-0.7-0.70.7-0.6-0.70.7-0.80.80.6-0.6-0.8-0.6-0.7-0.8-1.0
Intermittent access standard deviation0.00.00.10.00.20.10.1-0.10.20.1-0.00.1-0.0-0.20.20.10.2-0.3-0.0-0.2
Left kidney weight0.00.20.30.5-0.4-0.5-0.50.5-0.5-0.50.4-0.40.20.5-0.5-0.4-0.4-0.3-0.3-0.0
Right kidney weight0.10.50.70.8-0.8-0.8-0.80.8-0.8-0.80.8-0.70.50.7-0.7-0.8-0.7-0.8-0.7-0.6
Cocaine induced anxiety0.10.20.5-0.40.50.50.5-0.50.50.5-0.50.5-0.7-0.50.50.50.50.50.50.7
Post-drug Anxiety0.30.30.40.4-0.6-0.5-0.50.5-0.5-0.50.5-0.50.60.5-0.5-0.5-0.5-0.5-0.6-0.6
Baseline Anxiety0.40.71.30.6-0.8-0.8-0.80.8-0.8-0.80.9-0.81.10.8-0.8-0.8-0.8-0.6-0.9-1.1
Tail length0.31.62.01.3-1.2-1.4-1.41.4-1.4-1.41.4-1.41.31.4-1.4-1.4-1.3-1.1-0.9-0.7
Length with tail0.52.12.51.6-1.4-1.5-1.51.5-1.5-1.51.5-1.61.31.5-1.5-1.5-1.5-1.5-1.0-0.7
Length without tail0.10.71.21.1-0.9-0.9-0.90.9-0.9-0.90.9-0.90.70.9-0.9-0.9-0.8-1.1-0.6-0.5
Times rat made contact with spout0.00.00.2-0.20.10.00.0-0.00.00.0-0.0-0.0-0.2-0.0-0.0-0.00.00.40.10.3
Lifetime Intake0.30.41.20.7-0.6-0.5-0.50.5-0.5-0.50.6-0.60.70.5-0.4-0.6-0.4-1.0-0.8-1.1
Liver weight, left4.67.98.62.9-2.9-2.8-2.82.8-2.8-2.82.9-2.92.82.8-2.7-2.8-2.6-2.8-2.7-2.8
Liver weight, right3.76.57.22.7-2.6-2.6-2.62.6-2.6-2.62.6-2.62.52.6-2.6-2.6-2.6-2.4-2.4-2.2
Locomotor activity0.00.10.1-0.20.20.20.2-0.20.20.2-0.10.2-0.4-0.20.30.20.20.30.30.3
Locomotor testing distance0.10.10.2-0.30.30.40.4-0.40.40.4-0.30.4-0.4-0.40.40.40.40.40.20.1
Locomotor testing rearing0.00.00.2-0.30.10.10.1-0.10.10.2-0.10.1-0.1-0.10.10.20.10.5-0.0-0.1
Locomotion in novel chamber2.53.33.9-1.61.81.91.9-1.91.91.9-1.91.9-1.9-2.01.91.91.91.61.51.1
Locomotion in novel chamber post-restriction0.10.22.20.1-0.3-0.0-0.00.0-0.0-0.00.1-0.00.60.0-0.10.2-0.1-0.1-0.9-1.5
Fecal boli incidents, locomotor time 11.02.63.01.5-1.6-1.6-1.61.6-1.6-1.61.7-1.51.61.6-1.6-1.6-1.6-1.6-1.7-1.7
Change in fecal boli incidents, locomotor task0.40.40.7-0.50.70.60.6-0.60.60.6-0.60.6-0.5-0.60.60.80.60.50.90.9
Time >=10cm from walls, locomotor time 10.00.00.20.2-0.2-0.2-0.20.2-0.2-0.20.2-0.20.10.1-0.2-0.2-0.2-0.2-0.4-0.5
Bouts of movement, locomotor time 10.40.60.7-0.60.70.80.7-0.70.70.7-0.80.8-0.6-0.80.80.70.80.70.80.8
Total resting periods, locomotor time 10.10.10.2-0.30.30.30.3-0.30.30.3-0.40.4-0.3-0.30.30.30.30.30.40.5
Rest time, locomotor task time 10.20.30.50.5-0.6-0.6-0.60.6-0.6-0.60.6-0.60.70.6-0.6-0.4-0.6-0.6-0.4-0.5
Distance moved, locomotor task time 10.20.60.9-0.70.80.80.8-0.80.80.8-0.80.8-1.0-0.80.80.80.80.60.60.7
Vertical activity count, locomotor time 10.00.30.4-0.40.60.60.6-0.60.60.6-0.60.6-0.6-0.60.60.60.60.30.40.4
Time >=10cm from walls, locomotor time 20.30.91.10.9-0.9-0.9-0.90.9-0.9-0.90.9-1.00.60.9-1.0-1.0-1.0-1.0-1.0-0.9
Bouts of movement, locomotor time 20.20.51.6-0.70.70.60.6-0.60.60.6-0.70.6-0.7-0.60.60.70.60.71.01.2
Total resting periods, locomotor time 20.00.10.7-0.40.30.20.2-0.20.20.2-0.30.2-0.3-0.20.20.30.20.30.70.8
Rest time, locomotor task time 20.10.10.40.0-0.4-0.3-0.40.4-0.4-0.30.4-0.40.60.4-0.4-0.2-0.4-0.0-0.2-0.4
Distance moved, locomotor task time 20.50.70.9-0.60.80.90.9-0.90.90.9-0.90.9-1.0-0.90.90.80.90.60.60.6
Vertical activity count, locomotor time 20.51.31.7-0.71.21.11.1-1.21.21.1-1.21.2-1.3-1.21.21.21.20.61.11.1
Light reinforcement 10.00.00.1-0.10.20.20.2-0.20.20.2-0.20.3-0.2-0.20.20.10.20.20.10.1
Light reinforcement 20.30.60.9-0.80.80.80.8-0.80.80.8-0.70.8-0.8-0.80.70.70.70.90.91.0
Bone: marrow area0.00.10.2-0.10.20.20.2-0.20.20.2-0.20.1-0.4-0.20.20.20.30.20.40.5
Bone: maximum diameter0.40.80.9-0.80.90.90.9-0.90.90.9-0.80.9-0.9-0.90.91.00.90.90.91.0
Bone: maximum force0.51.11.2-0.91.11.01.0-1.01.01.0-1.01.0-1.0-1.01.01.11.11.01.11.1
Bone: maximum moment0.71.31.4-1.01.21.11.1-1.11.11.1-1.11.1-1.2-1.21.11.11.21.01.21.2
Mean time between licks in bursts0.10.81.00.9-0.9-0.9-0.90.9-0.9-0.90.9-0.90.90.9-1.0-0.9-1.0-0.8-0.9-0.8
Mean num. licks in bursts0.20.40.60.6-0.7-0.7-0.70.7-0.7-0.70.8-0.70.60.7-0.7-0.7-0.6-0.6-0.6-0.5
Cd content in liver0.91.01.5-0.91.01.01.0-1.01.01.0-1.11.0-1.1-1.00.81.10.81.01.11.2
Co content in liver0.30.40.6-0.60.60.60.6-0.60.60.6-0.70.6-0.6-0.60.50.70.40.80.50.5
Cu content in liver1.41.72.0-1.41.31.31.3-1.31.31.3-1.31.2-1.2-1.21.31.31.21.41.41.4
Fe content in liver2.02.42.61.5-1.6-1.6-1.61.6-1.6-1.61.6-1.61.51.6-1.6-1.5-1.6-1.4-1.6-1.5
K content in liver0.10.10.10.2-0.3-0.3-0.30.3-0.3-0.30.2-0.30.30.3-0.2-0.3-0.3-0.2-0.3-0.4
Mg content in liver0.60.61.0-0.90.80.70.7-0.70.70.7-0.80.7-0.8-0.70.70.80.71.00.80.9
Mn content in liver0.20.20.3-0.50.40.40.4-0.40.40.4-0.50.4-0.4-0.40.40.50.50.50.40.4
Na content in liver0.00.00.20.10.00.10.1-0.10.10.1-0.00.10.2-0.10.2-0.10.2-0.1-0.2-0.4
Rb content in liver0.00.00.10.2-0.2-0.2-0.20.2-0.2-0.20.2-0.20.20.2-0.2-0.2-0.1-0.2-0.1-0.2
Se content in liver0.60.71.0-0.90.80.80.8-0.80.80.8-0.80.7-0.8-0.80.90.81.00.90.80.7
Sr content in liver0.50.40.40.7-0.7-0.7-0.60.6-0.7-0.60.6-0.70.60.6-0.6-0.7-0.5-0.7-0.6-0.6
Zn content in liver0.30.40.50.6-0.6-0.7-0.70.7-0.7-0.70.6-0.70.60.7-0.7-0.6-0.7-0.5-0.4-0.3
Bone: minimum diameter0.10.10.3-0.30.40.40.4-0.40.40.4-0.30.4-0.4-0.40.30.50.30.40.30.3
Time in familiar zone, hab. session 10.30.40.5-0.60.60.60.6-0.60.60.6-0.60.6-0.5-0.60.60.60.70.50.50.4
Time in novel zone, hab. session 10.20.20.30.4-0.4-0.5-0.50.5-0.5-0.50.4-0.50.40.5-0.5-0.5-0.5-0.3-0.4-0.3
Total zone transitions, hab. session 10.10.10.1-0.20.30.30.3-0.30.30.3-0.40.3-0.4-0.30.30.30.20.20.30.3
Total locomotion distance, hab. session 10.10.10.3-0.30.30.30.3-0.30.30.3-0.40.3-0.5-0.30.30.30.30.30.40.5
Locomotion velocity, hab. session 10.30.50.8-0.70.70.70.7-0.70.70.7-0.80.7-0.9-0.70.70.70.60.70.70.8
Time in familiar zone, hab. session 20.10.10.2-0.40.30.30.3-0.30.30.3-0.30.3-0.3-0.30.30.30.20.40.30.3
Time in novel zone, hab. session 20.20.20.4-0.30.50.50.5-0.50.50.5-0.50.5-0.5-0.50.50.50.60.40.50.5
Total zone transitions, hab. session 20.30.40.60.5-0.6-0.6-0.60.6-0.6-0.60.5-0.60.50.6-0.6-0.6-0.7-0.7-0.8-0.8
Total locomotion distance, hab. session 20.00.00.1-0.30.10.20.2-0.20.20.2-0.20.2-0.4-0.20.20.20.10.20.00.1
Locomotion velocity, hab. session 20.00.10.2-0.30.20.20.2-0.20.20.2-0.30.2-0.4-0.20.20.20.20.30.10.1
Novel to familiar place preference ratio0.60.80.91.0-0.9-0.9-0.90.9-0.9-0.90.9-0.90.80.9-0.9-0.9-0.8-1.0-0.9-0.9
Novelty place preference0.91.11.21.1-1.1-1.1-1.01.0-1.0-1.11.1-1.11.01.0-1.1-1.1-0.9-1.1-1.1-1.0
Time in novel zone, NPP test1.01.21.31.1-1.1-1.1-1.11.1-1.1-1.11.1-1.11.01.1-1.1-1.1-1.0-1.1-1.1-1.1
Total zone transitions, NPP test0.00.00.00.1-0.1-0.1-0.10.1-0.1-0.10.0-0.1-0.00.1-0.1-0.1-0.2-0.1-0.2-0.2
Total locomotion distance, NPP test0.81.11.6-1.11.01.01.0-1.01.01.0-1.11.0-1.3-1.01.01.00.91.10.90.9
Locomotion velocity, NPP test0.91.31.9-1.21.11.21.2-1.21.21.2-1.21.2-1.4-1.11.21.21.11.21.01.0
Intraocular pressure0.91.41.8-1.31.21.21.2-1.21.21.2-1.21.2-1.2-1.21.21.11.21.01.11.1
Delta distance traveled before/after self-admin2.73.03.51.9-1.8-1.8-1.81.8-1.8-1.81.8-1.81.61.8-1.8-1.8-1.8-1.0-1.6-1.3
Delta ambulatory time before/after self-admin1.32.22.61.6-1.6-1.6-1.61.6-1.6-1.61.6-1.61.41.6-1.6-1.5-1.6-0.4-1.4-1.2
Parametrial fat weight6.314.915.63.8-3.9-3.9-3.93.9-3.9-3.93.9-3.83.83.9-3.9-3.8-3.9-3.7-3.9-3.7
Pavlov. Cond. lever latency0.00.00.10.2-0.2-0.2-0.20.2-0.2-0.20.2-0.20.10.2-0.2-0.2-0.2-0.0-0.00.1
Pavlov. Cond. magazine entry latency0.00.00.10.1-0.1-0.1-0.10.1-0.1-0.10.1-0.10.10.1-0.1-0.1-0.1-0.1-0.2-0.2
Pavlov. Cond. change in total contacts0.30.30.4-0.60.50.60.6-0.60.60.6-0.60.6-0.5-0.60.60.60.60.50.30.1
Pavlov. Cond. index score0.00.00.1-0.20.20.20.2-0.20.20.2-0.20.2-0.2-0.20.20.20.30.1-0.0-0.1
Pavlov. Cond. latency score0.00.00.0-0.10.00.10.1-0.10.10.1-0.10.1-0.0-0.10.10.10.1-0.0-0.1-0.2
Pavlov. Cond. lever contacts0.00.00.1-0.10.10.20.2-0.20.20.2-0.20.2-0.1-0.20.20.20.20.0-0.1-0.3
Pavlov. Cond. magazine entry number0.20.20.20.4-0.4-0.5-0.50.5-0.5-0.50.5-0.50.40.5-0.5-0.5-0.5-0.4-0.3-0.2
Pavlov. Cond. intertrial magazine entries0.20.20.3-0.50.50.40.4-0.40.40.4-0.50.4-0.5-0.40.40.40.50.40.50.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.30.30.30.4-0.40.40.3-0.30.4-0.3-0.40.40.40.40.20.1-0.0
Pavlov. Cond. response bias0.00.00.0-0.10.10.20.2-0.20.20.2-0.20.2-0.1-0.20.20.20.20.1-0.0-0.2
Pavlov. Cond. lever latency2.53.53.71.9-1.9-1.9-1.91.9-1.9-1.91.8-1.81.91.9-1.9-1.8-1.9-1.8-1.9-1.8
Pavlov. Cond. magazine entry latency0.20.30.4-0.50.50.50.5-0.50.50.5-0.50.5-0.5-0.50.50.50.60.50.60.6
Pavlov. Cond. change in total contacts0.92.22.4-1.51.51.51.5-1.51.51.5-1.41.4-1.5-1.51.51.41.51.41.61.5
Pavlov. Cond. index score2.03.13.3-1.81.81.81.8-1.81.81.8-1.71.7-1.8-1.71.81.71.81.71.81.7
Pavlov. Cond. latency score2.23.53.8-2.01.91.91.9-1.91.91.9-1.81.8-1.9-1.91.91.81.91.91.91.9
Pavlov. Cond. lever contacts1.21.82.0-1.41.31.41.4-1.41.41.4-1.31.3-1.4-1.31.41.31.41.31.31.3
Pavlov. Cond. magazine entry number0.00.00.10.2-0.2-0.2-0.20.2-0.2-0.20.2-0.10.20.2-0.2-0.1-0.2-0.2-0.3-0.2
Pavlov. Cond. intertrial magazine entries0.30.70.80.8-0.8-0.8-0.80.8-0.8-0.80.8-0.80.80.8-0.9-0.8-0.9-0.8-0.9-0.8
Pavlov. Cond. lever-magazine prob. diff.1.52.32.5-1.61.51.51.5-1.51.51.5-1.51.5-1.5-1.51.61.51.51.51.61.5
Pavlov. Cond. response bias1.21.61.8-1.31.31.31.3-1.31.31.3-1.21.2-1.3-1.31.31.21.31.21.31.3
Time in closed arm before self-admin1.01.83.71.3-1.2-1.1-1.11.1-1.1-1.11.2-1.11.51.1-1.1-1.2-1.2-1.9-1.6-1.9
Time in closed arm after self-admin1.01.21.5-0.91.21.21.2-1.21.21.2-1.11.2-0.9-1.21.21.11.20.30.90.6
Time in open arm before self-admin1.51.84.4-1.41.31.21.2-1.11.11.2-1.21.1-1.4-1.11.11.21.21.91.72.1
Time in open arm after self-admin1.01.11.31.1-1.1-1.1-1.11.1-1.1-1.11.1-1.11.11.1-1.1-1.0-1.0-0.4-1.0-0.9
Bone: periosteal estimation0.41.01.3-0.91.01.01.0-1.01.01.0-0.91.0-1.1-1.01.01.11.00.91.11.2
Bone: periosteal perimeter0.40.70.9-0.60.90.80.8-0.80.80.8-0.80.9-0.9-0.80.80.90.80.80.91.0
Bone: post-yield work0.20.30.50.6-0.5-0.5-0.50.5-0.5-0.50.5-0.50.60.5-0.5-0.5-0.4-0.5-0.6-0.7
Progressive ratio test 1 active lever presses0.40.71.0-0.80.90.90.9-0.90.90.9-0.80.8-0.7-0.91.00.81.00.50.70.3
Progressive ratio test 1 breakpoint0.50.81.0-0.81.01.01.0-1.01.01.0-0.90.9-0.7-1.01.00.91.00.60.70.4
Progressive ratio test 1 inactive lever presses1.12.83.3-1.51.81.71.7-1.71.71.7-1.71.6-1.7-1.81.81.71.81.21.61.4
Progressive ratio test 2 active lever presses0.30.40.5-0.60.60.70.7-0.70.70.6-0.60.6-0.5-0.70.70.70.70.40.40.2
Progressive ratio test 2 breakpoint0.20.30.4-0.60.60.60.6-0.60.60.6-0.50.5-0.5-0.60.60.60.60.40.40.2
Progressive ratio test 2 inactive lever presses0.00.20.4-0.30.50.40.4-0.40.40.4-0.30.4-0.4-0.40.40.60.40.20.30.3
Incentive Sensitization - Responses0.00.00.10.1-0.2-0.2-0.20.2-0.2-0.20.2-0.30.00.2-0.2-0.1-0.20.1-0.2-0.1
Incentive Sensitization - Breakpoint0.00.10.10.1-0.3-0.3-0.30.3-0.3-0.30.3-0.30.10.3-0.2-0.2-0.20.1-0.2-0.1
Sum of active levers in priming session hrs 5-61.71.61.81.2-1.3-1.3-1.31.3-1.3-1.31.3-1.31.31.3-1.3-1.3-1.3-0.7-1.3-1.2
Progressive ratio0.10.20.40.3-0.4-0.4-0.40.4-0.4-0.40.4-0.40.20.4-0.4-0.5-0.4-0.4-0.6-0.5
Food seeking constrained by brief footshock0.10.10.20.3-0.3-0.4-0.40.4-0.4-0.30.4-0.30.50.4-0.4-0.3-0.4-0.2-0.10.0
Seeking ratio, punishment vs. effort0.10.30.5-0.30.50.50.5-0.50.50.5-0.50.6-0.2-0.60.50.60.50.40.70.6
Retroperitoneal fat weight0.41.82.51.6-1.3-1.3-1.31.3-1.3-1.31.5-1.31.41.3-1.2-1.4-1.2-1.5-1.1-1.1
Reaction time number correct0.31.21.61.3-1.1-1.1-1.11.1-1.1-1.11.2-1.11.01.1-1.2-1.0-1.1-1.2-0.9-0.8
Reaction time mean minus median0.10.40.50.6-0.6-0.6-0.60.6-0.6-0.60.6-0.60.70.6-0.6-0.6-0.6-0.7-0.6-0.6
Reaction time mean minus median AUC0.32.32.91.5-1.4-1.5-1.51.5-1.5-1.51.5-1.41.71.5-1.5-1.5-1.5-1.7-1.5-1.6
Reaction time num false alarms4.67.98.4-2.82.82.82.8-2.82.82.8-2.82.8-2.9-2.82.92.72.92.82.82.8
Reaction time num false alarms AUC3.58.08.6-2.82.82.82.8-2.82.82.8-2.72.8-2.9-2.82.92.82.92.92.82.8
Reaction time trials correct on left0.31.21.61.3-1.1-1.1-1.11.1-1.1-1.11.2-1.11.01.1-1.2-1.0-1.1-1.2-0.9-0.8
Reaction time trials on left0.41.21.61.3-1.1-1.1-1.11.1-1.1-1.11.2-1.11.11.1-1.2-1.0-1.2-1.3-0.9-0.8
Reaction time mean0.51.11.41.0-1.0-1.1-1.11.1-1.1-1.11.0-1.01.11.1-1.1-1.1-1.2-1.0-0.9-0.9
Reaction time mean AUC0.30.81.10.9-0.9-0.9-0.90.9-0.9-0.90.9-0.91.00.9-1.0-0.9-1.0-0.9-0.8-0.7
Median of all reaction times0.50.81.00.9-0.9-0.9-0.90.9-0.9-0.90.8-0.90.90.9-1.0-0.9-1.0-0.8-0.8-0.7
Reaction time omissions1.01.62.31.4-1.3-1.3-1.31.3-1.2-1.31.2-1.21.31.2-1.2-1.3-1.3-1.5-1.2-1.3
Reaction time false alarm rate6.08.38.9-2.92.92.92.9-2.92.92.9-2.92.8-3.0-2.93.02.83.03.02.82.7
Reaction time premature initiation rate0.10.20.40.5-0.4-0.4-0.40.4-0.4-0.40.4-0.30.50.3-0.3-0.3-0.3-0.4-0.5-0.6
Reaction time premature initiations0.20.50.70.8-0.7-0.7-0.70.7-0.7-0.70.8-0.60.80.7-0.7-0.6-0.7-0.8-0.7-0.8
Std. dev. reaction times0.41.21.41.1-1.1-1.1-1.11.1-1.1-1.11.1-1.11.21.1-1.1-1.1-1.1-1.2-1.0-1.0
Reaction time trials completed0.41.21.61.3-1.1-1.1-1.11.1-1.1-1.11.2-1.11.11.1-1.2-1.0-1.2-1.3-0.9-0.8
Reaction time trials AUC0.31.01.41.2-1.0-1.0-1.01.0-1.0-1.01.1-1.01.01.0-1.1-0.9-1.1-1.1-0.9-0.7
Run reversals in cocaine runway, females0.10.10.50.2-0.1-0.2-0.20.2-0.2-0.20.1-0.3-0.10.2-0.3-0.3-0.2-0.20.30.7
Run reversals in cocaine runway, males0.10.10.80.3-0.3-0.2-0.10.1-0.1-0.10.1-0.20.20.1-0.20.1-0.20.1-0.7-0.9
Latency to leave start box in cocaine runway0.10.10.9-0.60.30.20.2-0.20.20.2-0.30.1-0.6-0.10.1-0.10.20.50.50.9
Latency to leave start box in cocaine runway, F0.00.00.1-0.2-0.1-0.1-0.10.2-0.2-0.10.1-0.2-0.10.2-0.2-0.4-0.10.30.10.4
Latency to leave start box in cocaine runway, M0.10.10.4-0.20.30.20.1-0.10.10.1-0.20.1-0.4-0.10.1-0.10.1-0.00.40.6
Std. dev. time between licks in bursts0.00.00.00.1-0.0-0.1-0.10.1-0.1-0.1-0.0-0.10.00.1-0.1-0.1-0.10.10.10.1
Total sessions with >9 infusions0.10.20.70.6-0.2-0.3-0.30.3-0.3-0.30.3-0.30.40.2-0.2-0.3-0.2-0.8-0.5-0.7
Short access day 1 total inactive lever presses1.83.65.62.1-1.8-1.8-1.81.8-1.8-1.81.9-1.92.01.8-1.7-1.8-1.7-2.4-1.8-2.0
Short access day 10 total inactive lever presses0.00.00.1-0.00.20.20.2-0.20.20.2-0.20.20.0-0.20.20.30.2-0.20.1-0.2
Short access day 1 total infusions0.20.41.10.9-0.5-0.5-0.50.5-0.5-0.50.6-0.40.80.4-0.5-0.3-0.5-1.1-0.8-1.0
Short access day 10 total infusions0.10.20.60.5-0.3-0.3-0.30.3-0.3-0.30.3-0.30.40.3-0.3-0.4-0.3-0.8-0.5-0.7
Short access total infusions0.10.10.60.3-0.0-0.0-0.0-0.00.0-0.00.1-0.10.3-0.00.1-0.00.0-0.8-0.4-0.8
Short access day 1 locomotion0.10.10.2-0.00.40.30.3-0.30.30.3-0.30.4-0.2-0.40.30.50.3-0.00.1-0.0
Short access day 10 total locomotion0.20.80.9-0.90.90.90.9-0.90.90.9-0.90.8-1.0-0.90.90.80.90.90.90.8
Short access total locomotion0.50.81.0-0.71.00.90.9-0.90.90.9-1.00.9-0.9-1.01.00.91.00.80.80.7
One hour access (0.3 mA shock)0.10.10.3-0.40.30.40.4-0.40.40.4-0.30.2-0.1-0.40.50.10.5-0.00.3-0.1
Compulsive drug intake0.81.11.61.0-1.2-1.0-1.01.0-1.0-1.01.1-1.01.31.0-1.0-1.1-1.0-1.1-1.2-1.3
One hour access (shock baseline)0.10.20.4-0.50.50.50.5-0.50.50.5-0.50.3-0.5-0.50.60.30.60.20.40.2
Social response proportion1.82.22.71.6-1.5-1.5-1.51.5-1.5-1.51.4-1.51.41.5-1.5-1.5-1.5-1.6-1.4-1.4
Social responses1.72.32.91.6-1.5-1.5-1.51.5-1.5-1.51.4-1.51.41.5-1.5-1.5-1.5-1.7-1.4-1.4
Social time1.11.72.51.4-1.3-1.3-1.31.3-1.3-1.31.2-1.21.51.2-1.3-1.2-1.3-1.3-1.5-1.6
Soleus weight2.26.67.02.6-2.6-2.6-2.62.6-2.6-2.62.6-2.52.62.6-2.6-2.5-2.6-2.4-2.6-2.6
Bone: stiffness1.52.83.21.8-1.7-1.7-1.71.7-1.7-1.71.7-1.71.61.7-1.7-1.7-1.7-1.8-1.6-1.6
Tibialis anterior weight2.79.410.23.1-3.1-3.1-3.13.1-3.1-3.13.2-3.13.13.1-3.1-3.0-3.1-3.0-3.1-3.0
Time to tail flick, vehicle, before self-admin0.00.10.70.1-0.1-0.1-0.00.0-0.0-0.10.0-0.00.10.0-0.0-0.0-0.0-0.9-0.2-0.3
Time to tail flick, vehicle, after self-admin0.30.50.7-0.60.80.80.8-0.80.80.8-0.80.8-0.6-0.80.80.80.70.50.70.4
Time to tail flick, test, before self-admin0.00.00.10.1-0.1-0.1-0.10.1-0.1-0.10.1-0.10.20.1-0.1-0.0-0.1-0.2-0.2-0.3
Time to tail flick, test, after self-admin0.10.10.8-0.60.20.20.2-0.20.20.2-0.10.2-0.2-0.10.20.20.30.90.20.3
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.60.40.40.4-0.40.40.4-0.50.4-0.5-0.40.40.40.40.90.60.6
Delta time to tail flick, test, before/after SA0.30.40.8-0.70.60.60.6-0.60.60.6-0.60.6-0.6-0.60.60.60.60.90.60.6
Tibia length0.00.10.2-0.30.30.30.3-0.30.30.3-0.30.3-0.3-0.30.30.40.40.30.40.4
Ambulatory time before self-admin0.82.42.9-1.51.61.71.7-1.71.71.7-1.71.7-1.5-1.71.71.61.70.21.31.0
Ambulatory time after self-admin0.00.00.0-0.00.00.00.0-0.00.00.0-0.00.0-0.0-0.00.0-0.1-0.0-0.2-0.1-0.2
Bone: tissue strength1.71.82.0-1.31.41.41.4-1.41.41.4-1.41.4-1.3-1.41.31.41.31.31.41.4
Total heroin consumption4.25.06.31.9-2.3-2.4-2.42.4-2.4-2.32.3-2.42.02.4-2.4-2.3-2.5-2.0-1.9-1.6
Bone: trabecular number2.85.35.62.2-2.4-2.3-2.32.3-2.3-2.32.3-2.42.32.3-2.3-2.3-2.2-2.3-2.4-2.4
Bone: trabecular spacing0.30.40.5-0.60.70.70.7-0.70.70.7-0.70.7-0.6-0.70.70.60.60.60.70.7
Bone: trabecular thickness0.00.00.0-0.00.10.10.1-0.10.10.1-0.00.1-0.2-0.10.00.10.10.00.10.2
Bone: trabecular tissue density1.11.92.0-1.41.41.41.4-1.41.41.4-1.41.4-1.3-1.41.41.31.41.41.41.4
Water consumed over 24 hours0.00.00.2-0.20.10.10.1-0.10.10.1-0.10.1-0.4-0.10.10.10.10.30.30.5
Number of responses in last shaping day1.01.32.2-1.01.21.21.2-1.21.21.2-1.11.5-0.7-1.21.01.51.01.11.00.9