Hub : Genes

Sectm1a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Sectm1a 0.08 0.04 1.0e-06 0.06 0.06 0.06 0.05 1.2e-06 1.2e-06 6.4e-07 5.2e-06
2 Brain gene expression Sectm1a 0.05 0.05 4.6e-03 0.01 0.02 0.01 0.01 3.2e-02 6.5e-03 5.3e-02 5.6e-02
3 NAcc gene expression Sectm1a 0.04 0.02 2.1e-05 0.02 0.03 0.03 0.02 1.1e-04 3.8e-05 7.3e-05 1.6e-04
4 BLA gene expression Sectm1a 0.16 0.09 1.0e-05 0.11 0.1 0.1 0.11 1.3e-06 6.1e-06 4.1e-06 2.7e-06
5 Liver isoform ratio XM_006247885.5 0.04 0.03 6.1e-03 0.02 0.01 0.01 0.02 1.4e-03 9.8e-03 1.0e-02 2.2e-03
6 Adipose gene expression Sectm1a 0.28 0.13 3.0e-09 0.06 0.07 0.08 0.06 5.8e-07 2.5e-08 3.7e-09 5.0e-07
7 pVTA gene expression Sectm1a 0.04 0.03 2.1e-03 0.03 0.02 0.02 0.02 3.1e-03 1.0e-02 1.1e-02 6.7e-03
8 Liver gene expression Sectm1a 0.2 0.1 5.1e-14 0.07 0.12 0.12 0.12 4.2e-08 2.1e-13 2.7e-13 8.7e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.20.41.0-0.70.70.4-0.81.0-0.60.10.6
Area under the delay curve0.30.52.70.2-0.20.80.0-0.4-0.6-1.70.4
BMI with tail0.31.13.21.3-0.60.21.80.9-1.30.80.5
BMI without tail0.42.26.9-0.91.00.1-0.72.6-2.21.11.3
Body weight0.41.83.71.4-1.0-1.21.41.6-1.21.90.2
Weight adjusted by age0.10.41.70.5-0.2-0.90.50.2-0.21.3-0.4
Bone surface0.10.30.8-0.70.5-0.3-0.90.50.20.5-0.1
Bone volume0.20.31.0-0.80.6-0.1-1.00.7-0.10.40.2
Breakpoint value in progressive ratio session1.22.24.41.6-1.8-1.80.8-1.22.10.9-1.1
Number of licking bursts0.30.81.4-0.91.00.7-0.90.9-1.2-0.60.8
Context. condit. distance diff. score2.73.34.4-2.12.11.5-1.82.1-1.7-0.91.9
Locomotion velocity, session 12.22.54.01.8-1.6-0.82.0-2.01.50.6-1.6
Locomotion distance, session 10.91.23.60.00.41.90.50.1-1.4-1.51.0
Locomotion velocity, session 20.70.92.31.0-0.80.61.0-1.50.5-1.2-0.4
Locomotion distance, session 20.81.13.2-0.20.51.40.10.7-1.8-1.11.1
Locomotion velocity, session 31.11.32.51.3-1.3-0.11.6-1.50.8-0.8-0.8
Locomotion distance, session 30.91.02.81.0-0.90.71.3-1.20.2-1.7-0.0
Stereotopy head waving bouts, day 30.70.81.61.1-0.9-0.31.3-1.00.80.7-0.8
Stereotopy head waving duration, day 30.30.30.80.7-0.40.10.9-0.60.40.5-0.4
Locomotion velocity, session 70.30.31.2-0.60.40.7-0.5-0.2-0.1-1.10.3
Locomotion distance, session 71.82.36.1-1.11.32.2-0.90.6-0.8-2.51.7
Stereotopy head waving bouts, day 70.10.10.30.3-0.2-0.30.10.1-0.10.6-0.2
Stereotopy head waving duration, day 70.00.10.30.2-0.0-0.2-0.10.2-0.20.5-0.1
Locomotion velocity, session 81.11.32.9-0.40.81.70.10.9-1.7-1.11.4
Locomotion distance, session 84.56.511.0-2.22.52.8-1.62.8-3.3-2.02.9
Degree of sensitization distance1.41.53.1-1.71.60.6-1.81.4-0.50.11.1
Degree of sensitization stereotypy0.10.10.3-0.00.1-0.0-0.10.5-0.60.10.2
Conditioned locomotion1.72.05.1-1.61.50.3-1.72.2-1.30.51.2
Cocaine response after cond. corrected0.40.71.41.2-1.1-0.60.8-0.80.80.0-0.6
Cocaine response after cond. not corrected0.40.51.21.1-1.0-0.20.7-0.90.5-0.6-0.4
Cocaine response before conditioning0.80.92.3-0.70.71.3-0.50.2-1.1-1.50.9
Saline control response0.71.02.4-1.31.0-0.2-1.31.5-0.90.50.7
Bone: connectivity density0.81.31.9-1.41.41.0-1.41.1-0.8-0.51.0
Bone: cortical apparent density0.30.51.30.5-0.40.60.7-1.10.7-1.0-0.2
Bone: cortical area2.13.47.52.3-1.8-1.52.70.7-1.22.5-0.8
Bone: cortical porosity4.04.45.72.0-2.2-2.42.0-1.81.92.0-2.3
Bone: cortical porosity3.13.45.21.7-1.9-2.31.6-1.31.62.2-2.0
Bone: cortical thickness4.37.218.53.7-3.0-2.14.3-0.1-0.73.1-1.6
Bone: cortical thickness1.72.15.52.1-1.6-0.92.3-0.2-0.41.5-0.7
Bone: cortical tissue density0.30.61.50.4-0.40.60.6-1.20.9-1.0-0.3
Condit. Reinf. active minus inactive responses0.30.41.5-0.20.3-0.4-0.11.2-0.51.00.3
Condit. Reinf. active-inactive response ratio0.10.10.50.2-0.1-0.30.20.7-0.30.60.1
Condit. Reinf. active responses0.70.93.5-0.70.8-0.5-0.51.9-0.91.10.6
Condit. Reinf. inactive responses0.30.41.1-0.80.8-0.2-0.71.1-0.50.50.4
Incentive salience index mean0.40.51.8-0.50.6-0.2-0.41.3-0.70.50.6
Condit. Reinf. lever presses0.60.91.1-0.90.90.8-0.90.9-0.9-1.01.0
Condit. Reinf. active minus inactive responses0.20.30.70.4-0.10.10.70.8-0.90.30.3
Condit. Reinf. active-inactive response ratio0.50.82.50.9-0.7-1.11.00.30.11.6-0.7
Condit. Reinf. active responses0.20.30.7-0.00.20.50.30.8-0.8-0.30.7
Condit. Reinf. inactive responses0.30.51.6-0.30.31.0-0.10.3-0.5-1.30.8
Condit. Reinf. lever presses0.50.71.4-0.80.80.7-0.71.2-0.9-0.31.0
Condit. Reinf. lever reinforcers received0.30.51.1-0.30.40.70.01.1-0.9-0.40.9
Conditioned reinforcement - actives0.10.41.2-0.40.30.6-0.40.5-1.0-1.10.5
Conditioned reinforcement - inactives0.00.10.30.3-0.1-0.3-0.20.50.50.20.2
Conditioned locomotion0.10.20.4-0.30.40.5-0.30.5-0.6-0.50.4
Patch foraging indifference point 0 sec0.00.10.2-0.50.1-0.1-0.30.40.0-0.10.1
Patch foraging indifference point AUC0.10.30.5-0.70.70.3-0.50.7-0.4-0.00.4
Delay disc. indifference point, 0s delay0.10.20.40.6-0.30.30.60.1-0.6-0.40.1
Delay disc. indifference point, 16s delay1.62.36.2-0.91.01.9-0.90.7-1.8-2.51.5
Delay disc. indifference point, 2s delay0.20.20.50.7-0.5-0.10.7-0.50.5-0.3-0.3
Delay disc. indifference point, 24s delay0.71.12.31.3-1.20.10.9-1.50.9-0.9-0.9
Delay disc. indifference point, 4s delay0.20.20.70.6-0.30.20.1-0.5-0.6-0.8-0.0
Delay disc. indifference point, 8s delay0.30.51.20.9-1.1-0.20.6-0.80.1-0.9-0.5
Indifference point function ln k0.20.51.70.4-0.30.80.6-0.5-0.7-1.30.3
Indifference point function log k0.20.51.70.4-0.30.80.6-0.5-0.7-1.30.3
Patch foraging total patch changes 0 sec0.00.10.3-0.50.20.0-0.30.6-0.3-0.30.3
Patch foraging total patch changes 12 sec0.10.20.5-0.2-0.0-0.6-0.10.20.70.6-0.3
Patch foraging total patch changes 18 sec0.30.81.1-0.90.90.9-0.61.0-0.8-0.81.0
Patch foraging total patch changes 24 sec0.00.10.6-0.20.2-0.2-0.00.8-0.20.50.2
Patch foraging total patch changes 6 sec0.10.20.5-0.2-0.1-0.6-0.10.3-0.00.7-0.4
Patch foraging time to switch 0 sec0.00.10.3-0.10.10.2-0.2-0.50.4-0.3-0.1
Patch foraging water rate 0 sec0.10.52.1-0.30.3-0.2-0.31.5-0.70.10.9
Patch foraging water rate 12 sec0.20.71.80.20.30.80.71.0-1.3-0.51.1
Patch foraging water rate 18 sec0.51.03.4-0.30.70.9-0.11.3-1.9-0.41.2
Patch foraging water rate 24 sec1.01.44.1-0.51.00.9-0.22.0-1.5-0.21.7
Patch foraging water rate 6 sec0.40.62.00.9-0.40.51.40.6-0.7-0.40.8
Seeking ratio, delayed vs. immediate footshock0.20.31.2-0.20.4-0.2-0.31.1-0.70.30.3
Distance traveled before self-admin0.30.71.80.7-0.9-1.40.3-0.30.81.0-0.9
Distance traveled after self-admin0.61.02.5-1.51.20.1-1.60.8-0.6-0.70.7
Extensor digitorum longus weight0.62.45.0-1.21.51.5-0.91.8-2.2-1.01.7
Bone: elastic displacement0.50.62.30.6-0.6-1.00.70.10.11.5-0.7
Bone: elastic work4.76.114.72.4-2.4-3.22.4-0.51.13.8-2.4
Bone: endosteal estimation0.61.42.1-1.41.41.0-1.51.0-0.8-1.01.3
Bone: endosteal perimeter0.10.30.8-0.70.3-0.6-0.90.40.10.8-0.1
Epididymis fat weight0.21.23.3-0.80.70.2-0.51.8-1.80.31.2
Delta time in closed arm before/after self-admin1.91.82.5-1.41.21.4-1.10.8-1.4-1.61.6
Delta time in open arm before/after self-admin0.20.31.40.2-0.1-0.20.4-0.61.20.2-0.2
Diff in mean of infusions in LGA sessions0.30.61.8-0.2-0.4-0.9-0.9-1.30.9-0.2-0.5
Delay discount exponential model param0.40.52.3-0.60.5-0.6-0.30.80.31.5-0.0
Extinction: sum of active levers before priming1.01.52.91.7-1.1-0.41.6-1.31.31.0-1.0
Active lever presses in extinction session 65.95.911.13.3-3.0-1.92.6-2.22.41.2-2.1
Bone: final force1.52.55.11.9-1.3-1.32.11.2-1.42.3-0.3
Bone: final moment1.93.17.42.0-1.6-1.72.21.0-1.12.7-0.7
Food consumed during 24 hour testing period0.20.30.9-0.90.6-0.1-1.00.7-0.10.30.2
Glucose10.316.426.24.5-4.4-2.64.3-5.14.81.2-4.0
Heart weight1.21.94.01.8-1.2-1.21.9-0.30.42.0-1.1
Delay discount hyperbolic model param0.30.41.7-0.60.6-0.5-0.40.90.11.30.1
Intermittent access intake day 1-15 change0.10.52.1-0.2-0.5-1.4-0.70.10.90.6-0.6
Intermittent access intake escalation0.10.41.7-0.2-0.5-1.3-0.70.10.60.4-0.5
Intermittent access intake escalation 21.22.05.10.5-1.1-2.3-0.1-0.62.01.7-1.3
Intermitt. access day 1 inactive lever presses0.11.64.0-1.51.10.1-1.32.0-1.3-0.21.3
Intermitt. access day 15 inactive lever presses0.21.11.9-1.21.30.6-1.31.4-0.9-0.21.1
Intermitt. access escalation Index0.51.53.1-1.81.20.6-1.81.2-1.1-0.51.1
Intermittent access day 1 total infusions0.10.21.00.3-0.10.1-0.20.6-1.0-0.1-0.1
Intermittent access day 15 total infusions0.10.30.8-0.30.1-0.5-0.90.8-0.60.1-0.0
Intermittent access terminal intake (last 3 days)0.20.31.0-0.40.0-0.8-1.00.8-0.10.4-0.2
Intermittent access total infusions0.30.40.9-0.30.1-0.1-0.90.9-1.0-0.60.2
Intermittent access day 1 locomotion0.20.31.00.1-0.20.4-0.10.2-0.9-1.00.4
Intermittent access day 15 total locomotion0.00.10.30.1-0.2-0.6-0.20.50.00.4-0.2
Intermittent access total locomotion0.10.10.20.0-0.3-0.2-0.30.4-0.4-0.40.2
Intermittent access standard deviation0.41.84.11.6-2.0-1.41.0-1.41.1-0.1-1.4
Left kidney weight0.21.85.42.1-1.6-0.72.3-0.50.40.9-0.8
Right kidney weight0.32.07.02.2-1.5-0.42.6-0.40.30.9-0.6
Cocaine induced anxiety2.67.210.33.2-3.1-2.82.7-2.02.82.4-2.3
Post-drug Anxiety5.15.89.03.0-3.0-2.22.6-1.82.71.5-2.1
Baseline Anxiety0.20.30.9-0.70.40.7-0.40.3-0.1-0.90.3
Tail length0.42.25.2-1.51.0-1.3-2.02.3-0.91.60.5
Length with tail0.41.85.31.3-1.6-2.30.70.20.61.6-1.0
Length without tail1.47.213.33.6-3.4-2.43.3-2.11.91.4-2.4
Times rat made contact with spout1.72.04.8-0.70.0-1.8-0.9-0.22.02.2-1.5
Lifetime Intake0.20.30.7-0.1-0.1-0.0-0.80.5-0.8-0.80.1
Liver weight, left0.40.71.41.1-1.2-0.10.9-1.10.4-0.9-0.4
Liver weight, right0.40.72.3-0.60.7-0.0-0.91.5-0.90.60.8
Locomotor activity0.10.10.30.3-0.20.30.3-0.60.6-0.3-0.1
Locomotor testing distance0.20.62.1-0.20.31.2-0.2-0.4-0.5-1.40.6
Locomotor testing rearing0.20.71.1-1.11.00.9-0.90.2-0.1-0.90.8
Locomotion in novel chamber0.30.41.6-0.20.50.9-0.30.2-0.6-1.30.6
Locomotion in novel chamber post-restriction0.31.02.7-1.20.6-1.0-1.61.3-0.21.00.2
Fecal boli incidents, locomotor time 10.10.40.8-0.60.70.9-0.80.2-0.3-0.40.5
Change in fecal boli incidents, locomotor task2.02.24.01.3-1.6-1.21.0-2.02.0-0.1-1.5
Time >=10cm from walls, locomotor time 11.82.23.3-1.71.60.9-1.81.8-1.4-0.91.5
Bouts of movement, locomotor time 10.20.30.80.7-0.40.30.5-0.90.3-0.5-0.6
Total resting periods, locomotor time 10.40.51.30.8-0.60.10.6-1.10.4-0.4-0.8
Rest time, locomotor task time 10.50.81.70.7-0.7-0.70.4-1.21.30.6-1.1
Distance moved, locomotor task time 10.10.40.7-0.40.10.1-0.50.7-0.8-0.80.8
Vertical activity count, locomotor time 10.10.81.5-0.70.70.4-0.91.2-0.9-0.51.2
Time >=10cm from walls, locomotor time 20.10.20.60.5-0.10.10.30.6-0.80.4-0.2
Bouts of movement, locomotor time 20.20.62.60.1-0.10.80.1-0.5-0.8-1.60.5
Total resting periods, locomotor time 20.20.93.1-0.40.41.1-0.4-0.0-1.3-1.80.9
Rest time, locomotor task time 20.20.41.2-1.10.50.1-0.9-0.4-0.4-0.60.0
Distance moved, locomotor task time 20.20.30.90.9-0.50.10.70.3-0.8-0.30.1
Vertical activity count, locomotor time 20.20.40.70.50.10.80.50.7-0.8-0.30.8
Light reinforcement 10.52.53.9-1.91.91.0-2.01.9-1.2-0.21.5
Light reinforcement 20.30.81.8-0.90.90.2-0.91.3-0.90.40.9
Bone: marrow area0.51.31.8-1.31.31.0-1.41.0-0.8-1.01.2
Bone: maximum diameter0.40.71.41.0-0.8-0.71.20.3-0.61.2-0.3
Bone: maximum force1.22.34.71.7-1.1-1.11.91.4-1.62.2-0.1
Bone: maximum moment1.52.86.91.9-1.3-1.62.11.2-1.22.6-0.5
Mean time between licks in bursts0.10.42.00.2-0.10.90.2-0.5-0.2-1.40.4
Mean num. licks in bursts0.61.53.80.3-0.6-1.50.2-0.71.91.7-1.4
Cd content in liver1.21.31.9-1.01.21.4-1.01.0-0.9-1.11.4
Co content in liver0.10.10.4-0.50.3-0.1-0.60.10.50.3-0.0
Cu content in liver0.70.92.20.3-0.8-1.50.1-0.50.91.3-1.1
Fe content in liver0.50.61.7-0.70.50.9-0.70.1-0.6-1.30.7
K content in liver3.43.35.8-2.31.91.1-2.42.1-1.4-0.81.8
Mg content in liver4.95.47.9-2.82.61.9-2.82.5-1.7-1.42.5
Mn content in liver0.10.10.30.10.00.20.20.3-0.60.00.2
Na content in liver0.70.81.1-1.00.80.8-1.00.7-0.6-0.91.0
Rb content in liver1.61.93.9-1.41.60.7-1.62.0-1.30.51.4
Se content in liver0.50.61.6-1.20.90.1-1.20.8-0.10.10.5
Sr content in liver2.01.72.61.2-1.4-1.21.1-1.51.30.9-1.6
Zn content in liver0.91.02.1-1.41.1-0.0-1.41.4-0.30.50.8
Bone: minimum diameter0.50.93.50.6-0.6-1.30.60.6-0.61.9-0.6
Time in familiar zone, hab. session 10.50.50.80.9-0.7-0.60.9-0.50.80.7-0.6
Time in novel zone, hab. session 10.20.20.3-0.60.50.5-0.50.4-0.5-0.40.4
Total zone transitions, hab. session 10.10.20.50.4-0.00.70.70.0-0.6-0.30.3
Total locomotion distance, hab. session 10.20.31.1-0.10.50.70.00.6-1.0-0.10.6
Locomotion velocity, hab. session 10.30.41.1-0.20.60.8-0.00.7-1.1-0.20.6
Time in familiar zone, hab. session 20.10.10.3-0.10.30.5-0.10.0-0.1-0.50.4
Time in novel zone, hab. session 20.00.00.10.3-0.20.10.4-0.1-0.3-0.10.0
Total zone transitions, hab. session 22.12.75.4-1.31.62.0-0.91.7-2.3-1.01.8
Total locomotion distance, hab. session 22.63.46.2-1.61.91.9-1.42.2-2.5-0.82.0
Locomotion velocity, hab. session 22.33.16.0-1.51.81.7-1.32.2-2.4-0.51.9
Novel to familiar place preference ratio1.31.63.51.1-1.3-1.91.0-0.40.71.8-1.4
Novelty place preference1.41.83.71.1-1.3-1.91.1-0.50.81.9-1.4
Time in novel zone, NPP test1.11.32.71.0-1.1-1.61.0-0.30.61.6-1.2
Total zone transitions, NPP test3.04.57.0-1.82.12.6-1.51.9-2.6-1.82.4
Total locomotion distance, NPP test3.65.07.3-2.02.32.4-1.82.4-2.7-1.42.5
Locomotion velocity, NPP test2.53.55.5-1.81.91.9-1.62.1-2.3-1.02.1
Intraocular pressure0.40.61.3-0.90.90.1-0.91.1-0.70.10.7
Delta distance traveled before/after self-admin1.01.11.8-1.31.21.0-1.00.2-0.7-1.31.0
Delta ambulatory time before/after self-admin1.22.03.5-1.91.71.5-1.40.3-0.9-1.81.2
Parametrial fat weight0.41.02.1-1.11.10.3-1.51.5-0.70.50.8
Pavlov. Cond. lever latency1.62.03.7-1.11.51.9-1.11.1-1.2-1.51.7
Pavlov. Cond. magazine entry latency1.82.35.01.3-1.6-2.21.2-0.71.41.7-1.6
Pavlov. Cond. change in total contacts2.32.53.01.7-1.7-1.71.5-1.41.51.2-1.7
Pavlov. Cond. index score1.21.54.00.8-1.1-2.00.8-0.30.81.7-1.3
Pavlov. Cond. latency score1.41.84.40.9-1.2-2.10.9-0.61.11.7-1.5
Pavlov. Cond. lever contacts0.50.61.40.5-0.8-1.20.5-0.50.50.8-0.9
Pavlov. Cond. magazine entry number3.44.47.9-1.82.12.8-1.81.3-2.0-2.32.3
Pavlov. Cond. intertrial magazine entries1.11.42.2-1.21.30.9-1.21.5-1.3-0.31.2
Pavlov. Cond. lever-magazine prob. diff.1.21.43.70.9-1.2-1.90.9-0.20.81.6-1.2
Pavlov. Cond. response bias2.53.15.61.6-1.9-2.41.6-1.11.61.8-1.9
Pavlov. Cond. lever latency1.21.63.01.6-1.5-0.71.5-1.70.9-0.2-1.3
Pavlov. Cond. magazine entry latency1.11.63.1-1.21.21.8-1.10.5-0.7-1.81.4
Pavlov. Cond. change in total contacts0.30.71.0-0.91.01.0-0.80.8-0.3-0.61.0
Pavlov. Cond. index score0.50.81.2-1.11.01.0-1.00.8-0.5-0.71.0
Pavlov. Cond. latency score0.81.21.6-1.31.31.2-1.31.0-0.6-0.71.2
Pavlov. Cond. lever contacts1.11.62.8-1.71.60.8-1.51.6-0.90.01.2
Pavlov. Cond. magazine entry number1.11.43.01.1-1.0-1.51.1-0.50.61.7-1.3
Pavlov. Cond. intertrial magazine entries0.20.41.4-0.20.5-0.3-0.41.2-0.80.90.3
Pavlov. Cond. lever-magazine prob. diff.0.50.81.1-1.01.01.0-1.00.7-0.4-0.81.0
Pavlov. Cond. response bias0.60.91.4-1.21.00.9-0.91.0-0.6-0.51.1
Time in closed arm before self-admin0.71.21.91.4-1.4-0.90.9-1.10.70.8-1.3
Time in closed arm after self-admin0.40.51.20.5-1.1-0.5-0.3-1.10.6-0.4-0.7
Time in open arm before self-admin1.61.93.6-1.21.51.4-1.31.3-1.9-1.11.2
Time in open arm after self-admin0.20.20.5-0.20.60.70.20.5-0.2-0.50.7
Bone: periosteal estimation0.20.61.20.6-0.4-0.50.80.9-1.11.00.1
Bone: periosteal perimeter1.93.77.92.0-1.9-2.41.9-0.50.72.8-1.8
Bone: post-yield work0.10.20.50.00.20.60.20.5-0.7-0.60.6
Progressive ratio test 1 active lever presses0.20.41.2-0.5-0.0-0.1-1.10.8-0.6-0.70.4
Progressive ratio test 1 breakpoint0.20.41.2-0.60.0-0.2-1.10.8-0.6-0.70.4
Progressive ratio test 1 inactive lever presses0.71.94.1-1.51.20.2-2.02.0-1.5-0.01.3
Progressive ratio test 2 active lever presses0.20.31.0-0.40.3-0.0-1.01.0-0.2-0.10.5
Progressive ratio test 2 breakpoint0.20.31.0-0.30.3-0.1-1.01.0-0.2-0.10.5
Progressive ratio test 2 inactive lever presses0.10.20.40.4-0.5-0.6-0.10.20.30.6-0.1
Incentive Sensitization - Responses0.20.51.3-0.60.70.0-1.11.10.20.60.4
Incentive Sensitization - Breakpoint0.20.41.1-0.50.6-0.0-0.91.10.40.70.3
Sum of active levers in priming session hrs 5-62.12.04.41.5-1.4-1.80.7-0.72.11.4-1.2
Progressive ratio0.10.20.40.5-0.40.40.4-0.6-0.2-0.6-0.1
Food seeking constrained by brief footshock0.60.71.40.4-0.8-1.0-0.1-1.01.10.6-1.2
Seeking ratio, punishment vs. effort0.10.20.5-0.60.50.0-0.50.7-0.10.30.2
Retroperitoneal fat weight0.83.49.1-2.01.7-0.1-2.13.0-1.91.11.5
Reaction time number correct2.17.310.7-2.62.92.9-2.03.0-2.6-2.03.3
Reaction time mean minus median0.10.71.60.5-0.7-0.90.4-1.31.10.4-1.1
Reaction time mean minus median AUC0.00.10.30.2-0.2-0.40.1-0.60.30.2-0.4
Reaction time num false alarms0.00.10.4-0.10.10.10.0-0.20.60.2-0.2
Reaction time num false alarms AUC0.00.10.2-0.20.30.5-0.1-0.20.2-0.20.1
Reaction time trials correct on left2.17.310.7-2.62.92.9-2.03.0-2.6-2.03.3
Reaction time trials on left2.27.611.0-2.63.03.0-2.13.0-2.7-2.13.3
Reaction time mean0.00.10.3-0.30.3-0.2-0.20.2-0.10.5-0.0
Reaction time mean AUC0.10.30.6-0.60.70.3-0.50.5-0.80.10.4
Median of all reaction times0.10.20.4-0.50.50.1-0.30.6-0.50.40.3
Reaction time omissions0.20.30.6-0.80.60.3-0.70.4-0.7-0.40.5
Reaction time false alarm rate1.21.62.81.0-1.1-1.10.9-1.61.70.9-1.6
Reaction time premature initiation rate0.10.10.30.00.00.40.1-0.50.5-0.6-0.1
Reaction time premature initiations0.72.23.8-1.41.61.9-1.11.1-1.0-1.61.7
Std. dev. reaction times0.00.10.3-0.20.10.10.0-0.50.1-0.2-0.2
Reaction time trials completed2.27.611.0-2.63.03.0-2.13.0-2.7-2.13.3
Reaction time trials AUC2.17.410.9-2.63.03.0-2.03.0-2.7-2.03.3
Run reversals in cocaine runway, females0.50.61.3-0.71.01.1-0.70.6-0.2-0.50.8
Run reversals in cocaine runway, males1.21.32.80.6-0.7-1.70.6-0.41.71.5-1.2
Latency to leave start box in cocaine runway0.30.40.8-0.90.80.8-0.4-0.0-0.3-0.40.6
Latency to leave start box in cocaine runway, F1.92.43.9-1.61.92.0-1.10.9-1.7-1.11.6
Latency to leave start box in cocaine runway, M0.50.51.40.2-0.8-0.80.5-0.81.20.5-0.6
Std. dev. time between licks in bursts2.75.18.0-1.92.22.2-1.82.5-2.8-1.82.7
Total sessions with >9 infusions0.30.31.50.2-0.30.3-0.50.3-0.7-1.20.1
Short access day 1 total inactive lever presses0.50.92.40.00.41.1-0.20.7-1.3-1.61.1
Short access day 10 total inactive lever presses0.10.82.4-0.80.7-0.1-1.01.6-0.6-0.01.1
Short access day 1 total infusions0.20.42.20.6-0.40.70.2-0.3-0.3-1.50.1
Short access day 10 total infusions0.30.52.1-0.4-0.2-1.0-1.50.7-0.2-0.1-0.3
Short access total infusions0.10.21.00.2-0.3-0.1-0.60.1-0.3-1.0-0.0
Short access day 1 locomotion0.40.61.61.3-1.2-0.50.8-0.70.4-0.2-0.7
Short access day 10 total locomotion0.31.42.21.3-1.5-1.20.7-1.31.30.0-1.3
Short access total locomotion0.60.92.11.3-1.5-1.00.6-0.90.6-0.3-1.0
One hour access (0.3 mA shock)0.40.41.0-0.60.80.2-1.01.0-0.50.20.5
Compulsive drug intake0.81.12.0-1.31.40.8-1.30.9-1.1-0.21.1
One hour access (shock baseline)0.10.40.8-0.60.40.2-0.80.9-0.8-0.40.3
Social response proportion0.30.41.4-0.1-0.00.70.30.3-0.5-1.20.8
Social responses0.50.61.9-0.1-0.00.90.20.2-1.2-1.40.7
Social time0.20.30.70.4-0.10.70.80.1-0.8-0.60.5
Soleus weight0.30.81.4-0.80.6-0.6-1.11.2-1.01.10.1
Bone: stiffness0.61.13.11.5-0.90.11.80.6-1.50.30.4
Tibialis anterior weight0.20.71.1-0.91.00.7-0.80.9-1.1-0.40.7
Time to tail flick, vehicle, before self-admin0.00.00.1-0.10.30.3-0.10.00.00.2-0.1
Time to tail flick, vehicle, after self-admin0.40.82.80.3-0.11.10.7-1.1-0.7-1.70.3
Time to tail flick, test, before self-admin0.00.10.2-0.2-0.2-0.00.30.1-0.1-0.5-0.0
Time to tail flick, test, after self-admin0.70.71.30.9-1.2-0.40.9-0.90.7-1.0-0.6
Delta time to tail flick, vehicle, before/after SA0.70.82.1-0.80.70.9-0.60.0-1.1-1.40.8
Delta time to tail flick, test, before/after SA1.11.42.61.6-1.4-0.61.6-1.21.00.3-1.0
Tibia length2.98.025.22.6-2.4-3.72.70.5-0.15.0-2.2
Ambulatory time before self-admin0.30.92.30.9-1.0-1.50.30.30.61.4-0.8
Ambulatory time after self-admin0.10.20.5-0.70.7-0.0-0.60.6-0.2-0.30.4
Bone: tissue strength0.60.61.9-0.00.30.20.21.4-1.40.60.7
Total heroin consumption2.42.95.52.3-2.1-1.41.9-1.91.30.6-1.5
Bone: trabecular number0.10.10.2-0.40.3-0.2-0.40.20.40.4-0.1
Bone: trabecular spacing3.04.36.7-1.72.02.1-1.82.1-2.6-1.72.5
Bone: trabecular thickness2.23.05.11.1-1.4-2.20.9-1.22.12.3-2.0
Bone: trabecular tissue density0.10.20.90.2-0.10.60.3-0.4-0.2-1.00.2
Water consumed over 24 hours0.40.71.60.2-0.6-1.00.2-0.91.30.9-1.2
Number of responses in last shaping day0.20.30.60.7-0.70.20.8-0.2-0.8-0.40.1