Hub : Genes

Sctr

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC alternative polyA NM_031115.1 0.18 0.08 2.8e-04 0.01 0.02 0.02 0.02 1.4e-01 3.5e-02 6.0e-02 5.2e-02
2 Liver alternative polyA XM_039091119.2 0.08 0.05 5.7e-06 0.01 0.02 0.01 0.01 1.7e-02 5.0e-03 4.7e-02 2.3e-02
3 PL gene expression Sctr 0.18 0.09 5.6e-11 0.07 0.06 0.04 0.06 5.0e-08 6.5e-07 6.0e-05 3.5e-07
4 Liver isoform ratio XM_039091119.2 0.11 0.06 2.8e-07 0.01 0.02 0.01 0.01 1.1e-02 3.1e-03 3.0e-02 1.3e-02
5 Adipose gene expression Sctr 0.03 0.02 4.6e-03 0.01 0 -0 0 2.0e-02 1.6e-01 6.2e-01 1.6e-01
6 Brain gene expression Sctr 0.1 0.06 3.4e-04 0.01 0.03 0.03 0.02 4.1e-02 6.6e-04 1.3e-03 9.8e-03
7 Liver gene expression Sctr 0.05 0.03 4.7e-03 0 0 -0 0 1.6e-01 1.4e-01 5.9e-01 2.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.20.31.1-0.00.30.50.3-0.6-0.1-1.0
Area under the delay curve5.66.59.52.9-3.1-2.9-3.12.9-1.20.1
BMI with tail1.34.67.72.1-0.8-2.5-0.72.5-2.82.5
BMI without tail0.82.54.11.7-0.9-1.8-0.81.7-2.01.7
Body weight1.04.26.32.4-1.4-2.4-1.32.5-2.51.3
Weight adjusted by age1.21.82.51.4-0.9-1.6-0.91.6-1.61.0
Bone surface0.30.61.1-0.00.9-0.11.00.0-1.11.0
Bone volume0.10.10.30.5-0.1-0.3-0.10.2-0.6-0.4
Breakpoint value in progressive ratio session0.80.91.51.0-1.2-1.1-1.21.1-0.3-0.0
Number of licking bursts0.20.20.60.2-0.7-0.3-0.80.40.5-0.2
Context. condit. distance diff. score0.10.20.4-0.0-0.5-0.3-0.60.30.60.3
Locomotion velocity, session 12.93.14.91.7-1.8-2.2-1.82.1-0.91.5
Locomotion distance, session 11.62.03.51.4-1.9-1.6-1.91.6-0.30.1
Locomotion velocity, session 23.54.16.42.4-2.5-2.1-2.52.1-1.0-0.5
Locomotion distance, session 21.21.72.71.6-1.6-1.4-1.61.3-0.6-0.4
Locomotion velocity, session 30.20.30.7-0.1-0.60.2-0.6-0.20.8-0.5
Locomotion distance, session 30.30.30.7-0.20.80.60.8-0.6-0.50.3
Stereotopy head waving bouts, day 30.30.40.9-0.4-0.00.8-0.0-0.80.8-0.9
Stereotopy head waving duration, day 30.40.52.0-0.6-0.30.3-0.4-0.41.4-0.5
Locomotion velocity, session 71.31.53.1-1.81.30.81.2-1.01.40.7
Locomotion distance, session 70.00.10.2-0.30.10.20.1-0.20.4-0.0
Stereotopy head waving bouts, day 70.40.41.4-0.2-0.40.5-0.5-0.40.9-1.2
Stereotopy head waving duration, day 70.10.10.3-0.1-0.30.1-0.4-0.00.6-0.4
Locomotion velocity, session 80.91.04.9-1.0-0.50.4-0.6-0.42.2-0.6
Locomotion distance, session 80.30.51.10.4-1.0-0.5-1.10.40.4-0.4
Degree of sensitization distance0.30.30.60.2-0.7-0.6-0.80.50.5-0.1
Degree of sensitization stereotypy0.50.62.0-0.3-0.30.7-0.3-0.60.9-1.4
Conditioned locomotion0.20.20.40.4-0.7-0.4-0.70.30.1-0.2
Cocaine response after cond. corrected0.40.52.1-0.70.1-0.30.00.30.71.5
Cocaine response after cond. not corrected0.50.61.8-0.6-0.3-0.4-0.40.51.11.3
Cocaine response before conditioning0.20.20.6-0.1-0.40.2-0.4-0.20.8-0.6
Saline control response0.40.61.50.3-1.00.2-1.0-0.10.7-1.2
Bone: connectivity density0.81.32.8-1.01.61.11.7-1.1-0.1-0.1
Bone: cortical apparent density1.31.85.0-0.6-0.21.5-0.2-1.51.6-2.2
Bone: cortical area0.50.81.2-0.90.51.00.4-1.01.1-1.0
Bone: cortical porosity0.40.40.9-0.30.90.51.0-0.5-0.60.5
Bone: cortical porosity0.20.20.40.00.50.10.5-0.1-0.60.6
Bone: cortical thickness1.11.82.7-1.40.91.60.9-1.71.4-1.1
Bone: cortical thickness2.02.33.4-1.51.01.80.9-1.81.6-1.7
Bone: cortical tissue density1.21.64.9-0.5-0.41.3-0.4-1.31.5-2.2
Condit. Reinf. active minus inactive responses0.10.10.60.5-0.0-0.10.00.2-0.80.1
Condit. Reinf. active-inactive response ratio0.30.30.7-0.70.30.70.3-0.60.8-0.4
Condit. Reinf. active responses0.50.72.61.1-0.2-0.5-0.10.6-1.60.4
Condit. Reinf. inactive responses0.70.83.21.2-0.3-0.6-0.20.6-1.80.5
Incentive salience index mean0.20.21.20.50.20.10.30.0-1.10.0
Condit. Reinf. lever presses0.20.21.10.30.40.20.5-0.1-1.00.1
Condit. Reinf. active minus inactive responses2.53.310.00.80.6-1.60.71.6-2.53.2
Condit. Reinf. active-inactive response ratio3.13.68.01.4-0.3-2.1-0.22.1-2.42.8
Condit. Reinf. active responses2.63.68.81.10.4-2.00.51.9-2.73.0
Condit. Reinf. inactive responses0.40.51.5-0.31.10.01.2-0.1-0.80.5
Condit. Reinf. lever presses0.40.51.00.8-0.2-0.8-0.20.7-1.00.8
Condit. Reinf. lever reinforcers received2.53.47.61.30.1-2.00.22.0-2.62.8
Conditioned reinforcement - actives0.10.10.20.4-0.5-0.4-0.50.4-0.10.1
Conditioned reinforcement - inactives0.10.10.2-0.00.30.50.3-0.3-0.2-0.5
Conditioned locomotion0.30.41.3-0.40.20.70.2-0.70.7-1.1
Patch foraging indifference point 0 sec1.12.15.6-0.9-0.61.2-0.7-1.42.4-2.1
Patch foraging indifference point AUC0.70.91.41.2-1.2-1.0-1.11.0-0.6-0.6
Delay disc. indifference point, 0s delay1.81.93.01.7-1.7-1.4-1.71.4-0.7-0.5
Delay disc. indifference point, 16s delay5.66.18.42.8-2.5-2.9-2.52.9-2.01.4
Delay disc. indifference point, 2s delay1.11.22.20.6-1.5-0.8-1.50.70.9-1.4
Delay disc. indifference point, 24s delay2.12.33.81.9-2.0-1.5-1.91.5-0.8-0.6
Delay disc. indifference point, 4s delay4.44.66.82.4-2.6-2.5-2.62.4-0.9-0.2
Delay disc. indifference point, 8s delay3.23.86.02.0-2.5-2.2-2.52.3-0.5-0.2
Indifference point function ln k0.10.20.4-0.50.50.30.4-0.20.20.6
Indifference point function log k0.10.20.4-0.50.50.30.4-0.20.20.6
Patch foraging total patch changes 0 sec0.91.64.1-0.5-0.80.9-0.9-1.02.0-1.9
Patch foraging total patch changes 12 sec1.31.75.3-0.3-1.00.5-1.0-0.61.9-2.3
Patch foraging total patch changes 18 sec0.91.33.6-0.6-0.50.8-0.6-0.91.8-1.9
Patch foraging total patch changes 24 sec0.50.82.4-0.8-0.10.7-0.1-0.91.5-1.0
Patch foraging total patch changes 6 sec1.01.54.0-0.4-0.80.7-0.9-0.82.0-2.0
Patch foraging time to switch 0 sec0.10.20.40.3-0.0-0.5-0.00.5-0.50.6
Patch foraging water rate 0 sec0.51.03.4-1.20.20.90.2-1.01.8-0.6
Patch foraging water rate 12 sec0.61.22.3-1.21.51.11.5-1.10.20.2
Patch foraging water rate 18 sec0.71.02.1-1.30.81.00.7-1.01.4-0.5
Patch foraging water rate 24 sec0.00.10.2-0.40.10.00.1-0.00.50.3
Patch foraging water rate 6 sec1.01.52.4-1.61.41.31.4-1.11.0-0.2
Seeking ratio, delayed vs. immediate footshock0.20.30.9-0.80.40.10.4-0.20.90.1
Distance traveled before self-admin0.30.40.80.6-0.9-0.6-0.90.50.0-0.6
Distance traveled after self-admin0.91.12.2-0.90.81.50.8-1.40.7-1.1
Extensor digitorum longus weight0.72.95.51.8-2.3-0.8-2.30.8-0.0-2.2
Bone: elastic displacement0.10.10.2-0.30.50.00.5-0.10.00.4
Bone: elastic work1.11.43.4-1.40.51.30.4-1.31.8-1.1
Bone: endosteal estimation0.10.20.20.4-0.5-0.5-0.50.5-0.10.2
Bone: endosteal perimeter0.30.61.30.7-0.6-1.1-0.61.1-0.60.5
Epididymis fat weight1.13.87.81.2-0.0-2.40.02.4-2.42.8
Delta time in closed arm before/after self-admin0.40.41.6-0.80.10.00.00.01.30.4
Delta time in open arm before/after self-admin3.53.45.92.4-2.4-1.2-2.31.3-1.2-1.6
Diff in mean of infusions in LGA sessions0.70.81.7-1.30.80.80.7-0.81.2-0.1
Delay discount exponential model param5.15.78.4-2.62.92.82.9-2.81.0-0.0
Extinction: sum of active levers before priming0.00.00.1-0.10.20.30.2-0.2-0.1-0.1
Active lever presses in extinction session 60.90.91.91.4-1.1-0.6-1.10.6-0.9-0.8
Bone: final force0.40.71.2-0.70.31.10.3-1.11.0-0.9
Bone: final moment0.40.71.2-0.70.21.00.2-1.11.1-0.9
Food consumed during 24 hour testing period0.30.40.80.9-0.6-0.7-0.60.7-0.80.2
Glucose3.04.78.01.9-1.1-2.8-1.12.8-2.32.3
Heart weight0.20.30.6-0.40.80.00.8-0.1-0.30.5
Delay discount hyperbolic model param4.85.48.3-2.52.92.72.9-2.70.70.1
Intermittent access intake day 1-15 change1.02.04.0-1.32.01.32.0-1.2-0.41.0
Intermittent access intake escalation1.53.15.3-1.92.31.92.3-1.80.30.6
Intermittent access intake escalation 21.72.03.3-1.71.81.51.8-1.30.60.6
Intermitt. access day 1 inactive lever presses0.10.51.70.8-0.60.2-0.5-0.1-0.5-1.3
Intermitt. access day 15 inactive lever presses0.30.61.40.00.90.51.0-0.5-1.20.5
Intermitt. access escalation Index0.20.30.70.4-0.7-0.0-0.70.00.1-0.8
Intermittent access day 1 total infusions0.10.20.5-0.40.20.40.2-0.50.7-0.3
Intermittent access day 15 total infusions1.92.84.1-1.91.92.01.9-2.01.1-0.2
Intermittent access terminal intake (last 3 days)1.11.42.2-1.41.21.51.1-1.51.0-0.3
Intermittent access total infusions0.70.91.4-1.01.01.11.0-1.20.5-0.0
Intermittent access day 1 locomotion0.60.82.7-0.0-0.70.5-0.7-0.71.1-1.6
Intermittent access day 15 total locomotion0.30.51.4-0.70.10.50.1-0.61.2-0.9
Intermittent access total locomotion0.40.40.8-0.50.20.80.1-0.90.8-0.8
Intermittent access standard deviation0.30.71.1-0.91.01.11.0-0.90.20.6
Left kidney weight2.411.217.74.1-4.2-3.1-4.13.1-1.5-2.4
Right kidney weight2.411.118.14.1-4.3-3.0-4.22.9-1.5-2.4
Cocaine induced anxiety0.81.23.50.50.7-0.50.80.5-1.91.6
Post-drug Anxiety1.11.22.1-0.31.40.51.4-0.5-1.31.4
Baseline Anxiety0.30.30.7-0.40.40.80.4-0.80.3-0.4
Tail length0.00.10.20.3-0.30.0-0.3-0.1-0.1-0.4
Length with tail0.31.31.91.4-1.4-1.2-1.41.3-0.6-0.5
Length without tail0.10.40.70.5-0.8-0.8-0.80.80.2-0.4
Times rat made contact with spout0.40.51.0-0.50.41.00.4-1.00.5-0.8
Lifetime Intake0.40.50.8-0.80.70.90.7-0.90.6-0.2
Liver weight, left0.20.41.60.8-0.0-0.30.00.4-1.2-0.3
Liver weight, right0.71.22.11.2-1.4-1.0-1.41.0-0.3-0.7
Locomotor activity3.04.78.02.8-2.1-2.3-2.02.4-2.30.2
Locomotor testing distance2.64.77.72.8-2.3-2.3-2.22.4-2.00.1
Locomotor testing rearing0.91.93.11.8-1.7-1.3-1.71.3-0.9-0.7
Locomotion in novel chamber0.81.01.9-0.90.51.40.5-1.31.0-1.1
Locomotion in novel chamber post-restriction0.00.10.1-0.20.10.30.1-0.30.2-0.3
Fecal boli incidents, locomotor time 10.81.22.20.70.1-1.40.11.2-1.51.5
Change in fecal boli incidents, locomotor task2.42.34.9-1.11.52.21.6-2.10.2-1.0
Time >=10cm from walls, locomotor time 10.40.51.0-0.61.00.61.0-0.6-0.10.3
Bouts of movement, locomotor time 11.21.32.11.4-1.1-1.3-1.11.4-1.0-0.0
Total resting periods, locomotor time 10.91.11.81.3-0.7-1.3-0.71.3-1.20.2
Rest time, locomotor task time 11.01.23.30.70.5-1.00.50.8-1.81.6
Distance moved, locomotor task time 10.81.12.10.1-1.40.1-1.40.01.5-1.4
Vertical activity count, locomotor time 11.02.36.5-1.2-0.31.3-0.4-1.22.6-2.2
Time >=10cm from walls, locomotor time 22.23.37.1-1.92.71.42.7-1.5-0.01.0
Bouts of movement, locomotor time 21.62.53.91.7-1.8-1.8-1.82.0-0.90.6
Total resting periods, locomotor time 21.93.45.12.1-2.0-2.1-2.02.3-1.30.6
Rest time, locomotor task time 21.01.32.81.5-0.8-1.1-0.71.0-1.70.7
Distance moved, locomotor task time 20.30.41.10.0-0.70.2-0.7-0.10.7-1.1
Vertical activity count, locomotor time 20.20.30.8-0.70.20.60.2-0.50.9-0.5
Light reinforcement 10.92.35.12.2-1.1-1.4-1.01.3-2.30.2
Light reinforcement 21.31.94.0-0.51.90.42.0-0.4-1.61.7
Bone: marrow area0.00.10.20.2-0.4-0.3-0.40.30.10.0
Bone: maximum diameter0.00.10.20.1-0.3-0.3-0.30.30.2-0.4
Bone: maximum force0.71.22.7-0.90.11.3-0.0-1.31.6-1.3
Bone: maximum moment0.61.12.7-0.8-0.11.1-0.1-1.21.7-1.3
Mean time between licks in bursts1.94.58.0-2.82.81.62.8-1.61.11.4
Mean num. licks in bursts0.40.61.0-0.50.90.91.0-1.0-0.1-0.3
Cd content in liver0.10.10.20.2-0.4-0.3-0.50.30.2-0.0
Co content in liver9.110.618.5-3.84.33.14.3-3.11.31.4
Cu content in liver4.75.69.8-2.11.73.11.7-3.11.9-2.4
Fe content in liver1.01.22.0-1.40.91.30.9-1.31.3-0.0
K content in liver0.20.20.90.40.3-0.20.40.2-1.00.2
Mg content in liver0.30.30.8-0.40.90.40.9-0.4-0.40.5
Mn content in liver0.20.20.50.7-0.3-0.1-0.20.1-0.7-0.6
Na content in liver2.12.25.50.41.0-1.21.11.2-2.12.3
Rb content in liver4.55.210.1-2.73.21.73.2-1.70.71.6
Se content in liver0.10.10.60.30.2-0.10.20.1-0.80.4
Sr content in liver1.31.23.11.0-0.1-1.10.01.1-1.71.3
Zn content in liver0.10.10.50.5-0.2-0.1-0.10.1-0.7-0.3
Bone: minimum diameter0.10.20.3-0.30.40.50.5-0.50.10.0
Time in familiar zone, hab. session 10.60.61.4-1.20.80.20.7-0.31.00.8
Time in novel zone, hab. session 10.20.20.50.30.20.50.3-0.6-0.7-0.6
Total zone transitions, hab. session 10.20.30.40.6-0.6-0.5-0.60.6-0.2-0.1
Total locomotion distance, hab. session 10.71.01.91.0-1.4-0.8-1.40.7-0.0-0.8
Locomotion velocity, hab. session 10.81.12.31.0-1.5-0.7-1.50.70.2-1.1
Time in familiar zone, hab. session 21.11.13.3-1.60.60.40.5-0.51.81.0
Time in novel zone, hab. session 21.01.02.61.5-0.7-0.5-0.60.6-1.6-0.7
Total zone transitions, hab. session 20.00.00.20.20.1-0.10.10.0-0.40.1
Total locomotion distance, hab. session 20.70.91.51.2-1.2-0.6-1.20.7-0.5-0.8
Locomotion velocity, hab. session 20.40.60.91.0-0.9-0.5-0.90.4-0.4-0.9
Novel to familiar place preference ratio1.82.04.02.0-1.2-1.2-1.11.3-1.9-0.0
Novelty place preference1.61.73.82.0-1.2-1.0-1.21.1-1.8-0.2
Time in novel zone, NPP test1.71.83.92.0-1.1-1.1-1.11.2-2.00.1
Total zone transitions, NPP test0.40.62.1-0.10.8-0.20.80.2-0.91.4
Total locomotion distance, NPP test0.20.30.60.8-0.6-0.1-0.60.1-0.5-0.7
Locomotion velocity, NPP test0.10.20.40.6-0.4-0.0-0.40.0-0.3-0.6
Intraocular pressure0.10.10.30.5-0.5-0.3-0.50.3-0.40.0
Delta distance traveled before/after self-admin1.61.73.0-1.41.41.71.4-1.60.8-0.3
Delta ambulatory time before/after self-admin0.81.02.2-0.81.01.51.0-1.40.3-0.4
Parametrial fat weight1.43.28.01.10.5-1.60.51.6-2.82.8
Pavlov. Cond. lever latency0.00.10.2-0.1-0.3-0.1-0.3-0.00.5-0.1
Pavlov. Cond. magazine entry latency0.50.71.3-1.11.10.51.1-0.50.40.7
Pavlov. Cond. change in total contacts0.20.20.6-0.00.60.20.7-0.1-0.70.4
Pavlov. Cond. index score0.50.61.2-0.91.10.61.1-0.50.10.5
Pavlov. Cond. latency score0.30.40.9-0.70.90.40.9-0.3-0.10.6
Pavlov. Cond. lever contacts0.20.20.3-0.40.60.60.6-0.5-0.0-0.2
Pavlov. Cond. magazine entry number0.91.22.11.4-1.5-1.0-1.40.9-0.5-0.5
Pavlov. Cond. intertrial magazine entries0.30.40.60.8-0.7-0.6-0.70.7-0.50.2
Pavlov. Cond. lever-magazine prob. diff.0.30.30.7-0.60.80.40.8-0.3-0.00.4
Pavlov. Cond. response bias0.40.51.0-0.81.00.71.0-0.60.10.2
Pavlov. Cond. lever latency1.21.62.8-1.71.21.41.2-1.31.3-0.1
Pavlov. Cond. magazine entry latency0.20.20.4-0.40.40.60.4-0.60.3-0.0
Pavlov. Cond. change in total contacts0.40.61.91.0-0.2-0.8-0.10.8-1.40.6
Pavlov. Cond. index score0.20.30.70.9-0.6-0.5-0.50.5-0.7-0.1
Pavlov. Cond. latency score0.00.10.20.4-0.2-0.1-0.20.1-0.3-0.2
Pavlov. Cond. lever contacts1.42.03.61.9-1.4-1.5-1.31.5-1.50.2
Pavlov. Cond. magazine entry number0.10.10.2-0.50.30.10.2-0.10.40.1
Pavlov. Cond. intertrial magazine entries0.40.62.5-0.20.5-0.60.50.5-0.61.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.8-0.6-0.5-0.50.5-0.6-0.0
Pavlov. Cond. response bias1.21.63.21.8-1.2-1.3-1.21.3-1.50.1
Time in closed arm before self-admin0.81.11.9-0.91.21.31.2-1.40.2-0.6
Time in closed arm after self-admin3.23.46.1-2.51.71.81.6-1.82.4-0.5
Time in open arm before self-admin0.60.62.10.0-0.2-1.1-0.21.0-0.01.5
Time in open arm after self-admin1.82.03.51.9-1.4-1.5-1.41.5-1.50.1
Bone: periosteal estimation0.10.10.30.0-0.5-0.1-0.50.00.6-0.4
Bone: periosteal perimeter0.00.10.1-0.1-0.2-0.3-0.20.40.40.3
Bone: post-yield work0.20.31.0-0.60.70.20.7-0.30.01.0
Progressive ratio test 1 active lever presses0.00.00.10.3-0.2-0.1-0.2-0.0-0.1-0.2
Progressive ratio test 1 breakpoint0.00.00.10.3-0.2-0.1-0.2-0.0-0.1-0.1
Progressive ratio test 1 inactive lever presses1.21.73.21.6-1.8-0.2-1.80.1-0.4-1.7
Progressive ratio test 2 active lever presses0.60.71.9-0.80.10.80.1-0.91.4-0.8
Progressive ratio test 2 breakpoint0.60.72.0-0.80.20.90.1-0.91.4-0.8
Progressive ratio test 2 inactive lever presses1.11.83.6-0.90.71.90.6-1.91.1-1.5
Incentive Sensitization - Responses0.20.30.7-0.70.30.50.3-0.50.9-0.1
Incentive Sensitization - Breakpoint0.30.41.0-0.70.30.60.3-0.61.0-0.2
Sum of active levers in priming session hrs 5-60.10.10.40.1-0.10.4-0.1-0.4-0.1-0.6
Progressive ratio0.30.51.10.1-0.8-0.1-0.80.11.0-0.8
Food seeking constrained by brief footshock0.10.10.4-0.0-0.10.2-0.1-0.20.3-0.6
Seeking ratio, punishment vs. effort0.30.40.7-0.10.80.00.8-0.0-0.90.9
Retroperitoneal fat weight2.611.239.60.71.9-2.62.02.7-4.16.3
Reaction time number correct0.10.20.40.4-0.3-0.6-0.30.6-0.40.5
Reaction time mean minus median0.30.61.60.6-0.1-0.8-0.10.8-1.11.3
Reaction time mean minus median AUC0.20.52.2-0.10.5-0.30.50.3-0.71.5
Reaction time num false alarms1.21.73.3-1.81.51.21.4-1.21.20.3
Reaction time num false alarms AUC0.30.40.8-0.90.60.60.6-0.60.70.1
Reaction time trials correct on left0.10.20.40.4-0.3-0.6-0.30.6-0.40.5
Reaction time trials on left0.10.20.30.4-0.3-0.5-0.30.6-0.40.5
Reaction time mean0.10.10.30.00.40.30.4-0.3-0.5-0.0
Reaction time mean AUC0.10.10.60.10.40.20.4-0.1-0.70.2
Median of all reaction times0.10.20.4-0.20.50.60.5-0.5-0.2-0.3
Reaction time omissions0.30.50.8-0.90.60.80.6-0.90.7-0.1
Reaction time false alarm rate0.60.81.5-1.21.00.91.0-0.90.80.1
Reaction time premature initiation rate0.40.52.20.50.60.10.6-0.1-1.50.7
Reaction time premature initiations0.30.52.00.60.3-0.20.40.2-1.40.8
Std. dev. reaction times0.10.10.4-0.00.30.00.30.0-0.50.6
Reaction time trials completed0.10.20.30.4-0.3-0.5-0.30.6-0.40.5
Reaction time trials AUC0.10.20.30.4-0.3-0.5-0.30.5-0.30.5
Run reversals in cocaine runway, females2.62.64.61.1-1.6-2.1-1.72.1-0.21.5
Run reversals in cocaine runway, males1.11.11.8-1.41.31.01.3-1.00.70.3
Latency to leave start box in cocaine runway0.81.02.2-0.41.40.31.5-0.2-1.01.0
Latency to leave start box in cocaine runway, F0.20.31.0-0.30.6-0.30.50.3-0.31.0
Latency to leave start box in cocaine runway, M0.70.61.30.01.10.61.1-0.5-1.2-0.0
Std. dev. time between licks in bursts0.71.01.7-1.21.30.61.3-0.50.41.1
Total sessions with >9 infusions0.20.20.7-0.2-0.10.6-0.1-0.60.5-0.8
Short access day 1 total inactive lever presses0.10.10.20.3-0.00.50.0-0.5-0.3-0.5
Short access day 10 total inactive lever presses1.53.68.22.2-1.0-1.9-0.92.0-2.91.7
Short access day 1 total infusions0.10.10.2-0.50.30.30.3-0.30.40.1
Short access day 10 total infusions0.40.51.2-0.5-0.00.6-0.1-0.71.1-0.9
Short access total infusions0.00.10.1-0.20.20.30.2-0.30.3-0.2
Short access day 1 locomotion0.10.10.30.5-0.30.2-0.3-0.3-0.5-0.3
Short access day 10 total locomotion0.10.30.7-0.1-0.40.5-0.4-0.60.6-0.8
Short access total locomotion0.20.20.50.20.00.70.1-0.7-0.4-0.5
One hour access (0.3 mA shock)0.00.00.2-0.10.1-0.30.10.40.20.2
Compulsive drug intake2.83.45.32.2-1.8-2.3-1.82.3-1.5-0.1
One hour access (shock baseline)2.33.55.4-2.31.82.11.8-2.11.8-0.2
Social response proportion3.13.56.4-2.52.51.12.4-1.01.11.4
Social responses0.30.40.8-0.90.80.40.8-0.30.50.5
Social time1.31.73.1-1.81.70.91.7-0.70.81.1
Soleus weight0.72.06.41.4-1.70.0-1.7-0.0-0.0-2.5
Bone: stiffness0.20.30.7-0.2-0.10.6-0.1-0.60.6-0.8
Tibialis anterior weight0.41.52.41.5-1.4-1.2-1.41.3-1.00.1
Time to tail flick, vehicle, before self-admin0.50.51.41.1-0.4-0.3-0.30.3-1.2-0.6
Time to tail flick, vehicle, after self-admin0.40.61.20.6-1.1-0.3-1.10.40.4-1.0
Time to tail flick, test, before self-admin4.44.56.1-2.42.32.42.2-2.51.6-1.1
Time to tail flick, test, after self-admin2.22.33.4-1.81.81.61.8-1.60.90.1
Delta time to tail flick, vehicle, before/after SA0.30.30.70.1-0.8-0.4-0.90.40.6-0.4
Delta time to tail flick, test, before/after SA1.91.93.11.3-0.8-1.6-0.81.6-1.51.8
Tibia length0.20.41.70.00.4-0.50.50.6-0.61.3
Ambulatory time before self-admin0.20.30.70.5-0.8-0.6-0.80.60.1-0.4
Ambulatory time after self-admin1.41.73.1-1.21.31.71.3-1.70.6-0.7
Bone: tissue strength0.90.91.4-1.11.20.71.2-0.70.31.0
Total heroin consumption2.32.75.71.3-2.3-1.1-2.41.00.7-1.8
Bone: trabecular number0.30.53.00.3-0.40.4-0.4-0.40.2-1.7
Bone: trabecular spacing0.91.25.20.20.1-1.20.11.2-0.82.3
Bone: trabecular thickness3.64.67.5-1.81.42.71.4-2.71.8-2.6
Bone: trabecular tissue density1.01.53.3-0.7-0.31.4-0.4-1.31.7-1.8
Water consumed over 24 hours0.20.20.80.4-0.50.3-0.4-0.20.0-0.9
Number of responses in last shaping day0.50.61.3-0.50.21.10.2-1.10.7-1.0