Hub : Genes

Rxrb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC alternative TSS XM_006255960.5 0.34 0.15 6.7e-03 0.09 0.02 0.02 0.06 3.1e-03 1.2e-01 9.3e-02 1.4e-02
2 OFC alternative TSS XM_006255961.5 0.33 0.15 8.7e-03 0.06 0.01 0 0.05 1.3e-02 1.5e-01 2.7e-01 2.8e-02
3 Brain isoform ratio NM_206849.3 0.04 0.03 4.5e-03 0.03 0.02 0.01 0.02 4.3e-04 1.1e-02 5.7e-02 8.8e-03
4 Brain gene expression Rxrb 0.07 0.04 1.4e-05 0.05 0.04 0.04 0.05 2.4e-05 1.5e-04 1.6e-04 4.0e-05
5 pVTA gene expression Rxrb 0.05 0.03 3.4e-03 0.03 0.02 0.01 0.01 3.7e-03 1.2e-02 2.3e-02 2.3e-02
6 Brain alternative TSS NM_206849.3 0.06 0.04 1.5e-04 0.02 0.02 0.01 0.02 3.7e-03 2.4e-03 3.0e-02 1.2e-02
7 Brain alternative TSS XM_006255960.5 0.05 0.03 1.0e-03 0.02 0.02 0.01 0.01 1.1e-02 6.7e-03 2.1e-02 1.2e-02
8 NAcc gene expression Rxrb 0.09 0.05 1.1e-06 0.05 0.04 0.05 0.06 4.7e-08 2.1e-07 1.9e-08 6.9e-09
9 PL gene expression Rxrb 0.12 0.07 5.3e-07 0.07 0.06 0.07 0.06 2.8e-08 9.1e-07 2.3e-08 2.8e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.12.04.0-1.91.90.3-2.0-1.81.0-1.10.80.6
Area under the delay curve0.20.20.50.6-0.6-0.30.70.3-0.40.3-0.40.1
BMI with tail1.44.912.1-1.21.2-3.51.42.1-2.82.7-2.1-1.5
BMI without tail1.03.06.2-0.50.5-2.52.31.6-2.32.3-1.2-0.6
Body weight2.310.216.11.1-1.1-3.53.93.8-3.94.0-3.3-2.4
Weight adjusted by age2.53.77.21.1-1.1-1.01.92.6-1.91.9-2.7-2.3
Bone surface0.10.10.30.4-0.40.30.0-0.60.5-0.40.40.2
Bone volume0.10.20.6-0.60.6-0.0-0.5-0.80.4-0.40.40.2
Breakpoint value in progressive ratio session0.40.41.10.3-0.30.4-0.4-0.70.8-0.70.91.1
Number of licking bursts0.81.33.31.8-1.81.2-0.3-0.61.1-0.90.80.9
Context. condit. distance diff. score3.23.96.42.0-2.02.3-2.5-2.02.3-2.21.00.6
Locomotion velocity, session 11.61.83.90.8-0.82.0-0.9-1.51.6-1.61.11.1
Locomotion distance, session 10.91.22.9-1.11.10.5-1.7-1.41.0-1.10.80.4
Locomotion velocity, session 20.70.81.40.7-0.70.8-0.6-1.21.1-1.01.00.9
Locomotion distance, session 20.30.42.4-0.20.20.2-1.6-0.50.4-0.5-0.1-0.3
Locomotion velocity, session 30.30.41.2-0.90.9-0.00.4-0.20.3-0.41.10.4
Locomotion distance, session 31.21.42.2-0.80.80.9-1.5-1.11.4-1.51.50.5
Stereotopy head waving bouts, day 31.21.43.11.7-1.70.01.71.5-0.60.8-0.8-0.7
Stereotopy head waving duration, day 30.80.92.61.3-1.30.21.61.2-0.50.6-0.4-0.2
Locomotion velocity, session 71.11.25.7-0.70.70.8-2.4-1.11.0-1.10.2-0.3
Locomotion distance, session 72.33.08.3-0.80.81.7-2.9-1.81.9-2.11.21.0
Stereotopy head waving bouts, day 70.80.92.90.5-0.50.90.2-0.60.9-0.91.71.2
Stereotopy head waving duration, day 70.20.20.80.3-0.30.20.90.30.1-0.10.80.5
Locomotion velocity, session 82.42.98.72.9-2.91.9-0.1-0.81.5-1.30.60.7
Locomotion distance, session 81.82.67.71.4-1.41.7-2.8-1.51.9-1.80.5-0.0
Degree of sensitization distance0.50.51.81.3-1.30.60.0-0.10.2-0.1-0.60.4
Degree of sensitization stereotypy1.61.85.00.0-0.01.2-0.8-1.51.4-1.52.21.6
Conditioned locomotion0.60.71.00.7-0.7-0.91.00.7-0.81.0-1.0-0.9
Cocaine response after cond. corrected0.50.61.60.3-0.3-0.8-0.30.7-0.60.7-1.3-1.2
Cocaine response after cond. not corrected0.70.92.01.4-1.4-0.50.80.8-0.50.7-1.0-0.7
Cocaine response before conditioning1.41.66.41.8-1.80.22.50.8-0.30.50.40.5
Saline control response1.72.33.8-1.41.4-1.91.91.1-1.91.8-0.7-0.7
Bone: connectivity density0.50.72.0-1.21.20.1-1.4-1.10.5-0.5-0.1-0.1
Bone: cortical apparent density1.41.83.7-1.51.5-1.91.01.0-1.51.5-0.8-1.0
Bone: cortical area0.10.10.30.6-0.6-0.20.6-0.2-0.10.20.3-0.1
Bone: cortical porosity1.92.15.00.5-0.51.9-0.3-1.11.5-1.62.21.9
Bone: cortical porosity1.81.94.71.0-1.02.2-0.2-0.81.5-1.51.91.4
Bone: cortical thickness0.50.82.4-1.51.5-1.30.4-0.4-0.60.50.6-0.2
Bone: cortical thickness1.41.74.1-1.61.6-2.01.20.6-1.31.3-0.3-1.0
Bone: cortical tissue density1.31.73.3-1.41.4-1.81.11.1-1.51.4-0.9-1.0
Condit. Reinf. active minus inactive responses0.70.81.8-0.30.31.3-0.5-1.20.9-1.00.71.1
Condit. Reinf. active-inactive response ratio0.20.20.5-0.60.6-0.10.7-0.2-0.30.2-0.00.3
Condit. Reinf. active responses0.40.50.8-0.80.80.8-0.7-0.90.6-0.70.10.6
Condit. Reinf. inactive responses0.91.12.7-1.71.70.2-1.6-1.00.6-0.70.40.5
Incentive salience index mean1.21.52.80.5-0.51.7-1.3-1.61.4-1.40.71.2
Condit. Reinf. lever presses1.42.04.41.2-1.21.6-2.1-1.51.6-1.50.41.1
Condit. Reinf. active minus inactive responses0.30.31.30.7-0.70.21.20.2-0.30.30.10.7
Condit. Reinf. active-inactive response ratio0.60.72.21.5-1.50.51.30.4-0.30.4-0.30.2
Condit. Reinf. active responses0.10.10.8-0.00.00.20.5-0.10.1-0.10.40.9
Condit. Reinf. inactive responses0.20.31.1-1.11.1-0.60.0-0.0-0.20.10.40.3
Condit. Reinf. lever presses1.01.32.3-0.40.41.3-1.0-1.51.2-1.31.51.2
Condit. Reinf. lever reinforcers received0.20.31.10.1-0.10.60.3-0.40.4-0.40.71.1
Conditioned reinforcement - actives0.10.20.7-0.60.6-0.8-0.6-0.2-0.20.1-0.40.2
Conditioned reinforcement - inactives0.10.10.5-0.40.4-0.3-0.30.3-0.30.2-0.70.2
Conditioned locomotion0.10.10.40.1-0.10.1-0.50.1-0.20.1-0.7-0.3
Patch foraging indifference point 0 sec1.32.34.5-1.11.1-2.12.11.6-1.81.7-0.9-0.0
Patch foraging indifference point AUC0.20.30.60.5-0.50.60.70.40.4-0.30.60.8
Delay disc. indifference point, 0s delay0.20.31.01.0-1.0-0.20.20.4-0.10.2-0.1-0.5
Delay disc. indifference point, 16s delay0.10.10.4-0.60.6-0.5-0.1-0.1-0.30.1-0.10.0
Delay disc. indifference point, 2s delay0.70.72.41.5-1.50.30.90.7-0.20.2-0.70.2
Delay disc. indifference point, 24s delay0.20.20.70.2-0.2-0.10.80.6-0.50.4-0.8-0.2
Delay disc. indifference point, 4s delay0.60.72.40.9-0.9-0.81.50.7-0.60.7-0.00.3
Delay disc. indifference point, 8s delay0.10.10.40.2-0.20.00.30.2-0.20.2-0.6-0.3
Indifference point function ln k0.50.81.40.9-0.91.0-0.1-1.21.0-0.91.00.6
Indifference point function log k0.50.81.40.9-0.91.0-0.1-1.21.0-0.91.00.6
Patch foraging total patch changes 0 sec1.22.34.3-1.21.2-2.12.01.6-1.81.7-0.90.0
Patch foraging total patch changes 12 sec1.01.32.4-1.01.0-1.51.51.5-1.21.1-0.5-0.4
Patch foraging total patch changes 18 sec2.03.05.9-2.22.2-2.40.81.8-1.81.7-1.0-0.7
Patch foraging total patch changes 24 sec0.71.34.5-2.12.1-1.2-0.60.3-0.60.4-0.20.0
Patch foraging total patch changes 6 sec1.11.73.4-1.41.4-1.91.11.0-1.61.5-0.9-0.2
Patch foraging time to switch 0 sec1.32.75.7-1.21.2-2.3-0.21.2-1.71.6-1.9-2.4
Patch foraging water rate 0 sec0.30.61.50.4-0.4-0.10.91.2-0.80.8-0.9-0.4
Patch foraging water rate 12 sec0.20.40.9-1.01.00.0-0.4-0.50.2-0.20.70.7
Patch foraging water rate 18 sec0.30.40.8-0.30.3-0.90.80.6-0.80.8-0.4-0.4
Patch foraging water rate 24 sec0.20.20.5-0.70.7-0.70.30.3-0.30.30.30.6
Patch foraging water rate 6 sec0.10.20.3-0.50.5-0.60.60.5-0.40.4-0.00.0
Seeking ratio, delayed vs. immediate footshock0.70.94.1-0.10.1-0.92.0-0.1-0.00.21.31.3
Distance traveled before self-admin0.40.51.20.5-0.5-1.00.21.1-0.60.7-0.6-0.4
Distance traveled after self-admin0.60.83.10.7-0.7-0.71.80.7-0.70.9-0.3-0.3
Extensor digitorum longus weight0.10.41.71.3-1.30.1-0.40.30.00.0-0.30.2
Bone: elastic displacement0.20.30.6-0.80.80.3-0.2-0.70.2-0.30.6-0.0
Bone: elastic work0.00.10.2-0.00.0-0.20.3-0.0-0.40.3-0.1-0.4
Bone: endosteal estimation2.24.813.83.7-3.70.12.32.2-1.01.2-1.5-0.7
Bone: endosteal perimeter1.22.610.43.2-3.20.80.90.80.10.1-0.7-0.2
Epididymis fat weight4.314.734.0-5.25.2-5.81.01.9-4.03.7-2.3-2.3
Delta time in closed arm before/after self-admin0.50.51.30.5-0.5-0.90.71.1-0.80.8-0.5-0.2
Delta time in open arm before/after self-admin0.20.20.5-0.70.70.4-0.3-0.60.1-0.2-0.1-0.3
Diff in mean of infusions in LGA sessions0.50.62.5-0.10.10.5-1.6-1.10.9-0.80.30.2
Delay discount exponential model param0.20.20.5-0.60.60.2-0.7-0.20.3-0.20.3-0.2
Extinction: sum of active levers before priming0.40.40.91.0-1.00.8-0.30.30.4-0.30.10.7
Active lever presses in extinction session 60.20.20.8-0.70.70.1-0.9-0.2-0.20.1-0.20.1
Bone: final force2.33.66.5-0.00.0-2.51.92.1-2.32.4-1.9-1.9
Bone: final moment1.72.74.5-0.00.0-2.11.51.9-2.02.0-1.6-1.7
Food consumed during 24 hour testing period1.21.62.81.1-1.1-0.90.71.6-1.21.3-1.6-1.7
Glucose2.64.112.73.6-3.62.8-0.40.81.2-1.0-0.40.3
Heart weight0.71.13.81.2-1.20.02.00.7-1.01.0-0.8-0.2
Delay discount hyperbolic model param0.20.20.6-0.70.70.2-0.8-0.20.2-0.10.1-0.5
Intermittent access intake day 1-15 change0.00.00.2-0.10.10.10.3-0.40.2-0.10.20.1
Intermittent access intake escalation0.10.20.7-0.80.8-0.20.4-0.5-0.00.00.50.1
Intermittent access intake escalation 20.20.20.60.2-0.20.70.0-0.70.5-0.50.60.1
Intermitt. access day 1 inactive lever presses0.20.72.91.7-1.70.00.30.10.3-0.1-0.10.4
Intermitt. access day 15 inactive lever presses0.20.41.00.4-0.4-0.40.51.0-0.60.6-1.0-0.7
Intermitt. access escalation Index0.81.21.90.3-0.30.8-1.4-1.41.3-1.11.31.1
Intermittent access day 1 total infusions0.60.94.4-0.70.70.9-2.1-0.60.7-1.0-0.10.6
Intermittent access day 15 total infusions0.40.51.2-1.11.10.2-1.0-0.70.3-0.50.20.6
Intermittent access terminal intake (last 3 days)0.20.30.7-0.80.80.3-0.7-0.40.2-0.40.00.6
Intermittent access total infusions0.40.51.4-0.90.90.5-1.2-0.50.3-0.5-0.10.6
Intermittent access day 1 locomotion0.20.30.6-0.80.8-0.4-0.80.3-0.20.1-0.6-0.3
Intermittent access day 15 total locomotion0.61.11.7-0.10.1-1.30.91.3-1.21.1-1.3-1.3
Intermittent access total locomotion0.40.51.0-0.80.8-1.00.10.6-0.70.5-0.8-1.0
Intermittent access standard deviation0.91.93.7-0.70.7-1.91.61.3-1.61.6-1.4-0.8
Left kidney weight1.36.212.1-0.20.2-3.33.52.7-3.23.2-1.8-1.3
Right kidney weight1.67.312.0-0.00.0-3.33.43.1-3.43.5-2.4-2.1
Cocaine induced anxiety0.10.10.40.6-0.6-0.0-0.00.00.2-0.00.10.4
Post-drug Anxiety0.20.20.70.5-0.5-0.90.50.2-0.20.3-0.20.4
Baseline Anxiety0.20.20.40.0-0.0-0.70.60.4-0.50.5-0.6-0.5
Tail length1.04.110.33.2-3.20.53.11.8-0.91.1-0.7-0.1
Length with tail1.87.715.13.5-3.5-0.63.93.2-2.22.5-2.3-1.8
Length without tail3.210.317.02.2-2.2-2.53.24.1-3.53.6-3.7-3.3
Times rat made contact with spout1.21.43.6-1.91.90.1-0.9-1.10.5-0.71.30.8
Lifetime Intake0.20.31.0-0.80.80.2-1.0-0.10.1-0.3-0.30.5
Liver weight, left1.52.56.12.5-2.5-0.41.81.8-0.71.0-1.0-0.7
Liver weight, right1.52.69.53.1-3.10.21.41.0-0.40.6-1.0-0.2
Locomotor activity0.50.92.31.3-1.3-0.21.50.80.20.00.61.0
Locomotor testing distance0.30.61.61.1-1.1-0.41.01.20.00.2-0.00.1
Locomotor testing rearing0.61.22.91.1-1.1-1.01.21.7-0.81.0-1.0-0.6
Locomotion in novel chamber0.10.10.3-0.30.3-0.60.3-0.3-0.10.10.1-0.0
Locomotion in novel chamber post-restriction0.91.42.2-0.30.3-1.41.11.3-1.51.4-1.5-1.2
Fecal boli incidents, locomotor time 10.20.31.5-0.50.50.3-1.2-0.00.0-0.1-0.7-0.2
Change in fecal boli incidents, locomotor task1.41.43.21.8-1.8-0.21.81.1-0.50.7-1.0-0.4
Time >=10cm from walls, locomotor time 12.93.16.81.5-1.5-1.51.92.6-1.61.9-1.8-1.0
Bouts of movement, locomotor time 11.01.12.7-0.10.10.5-0.6-1.61.0-1.01.61.6
Total resting periods, locomotor time 10.70.71.60.1-0.10.7-0.6-1.20.9-0.91.11.2
Rest time, locomotor task time 10.60.71.90.6-0.60.9-0.4-0.70.8-0.81.41.1
Distance moved, locomotor task time 10.81.22.6-0.10.1-0.91.01.4-1.21.2-1.6-1.2
Vertical activity count, locomotor time 11.22.95.4-0.60.6-1.91.62.0-1.91.9-2.3-1.6
Time >=10cm from walls, locomotor time 23.04.510.81.5-1.5-0.91.83.3-1.81.9-2.9-2.4
Bouts of movement, locomotor time 20.40.62.20.3-0.30.10.4-0.90.7-0.61.51.1
Total resting periods, locomotor time 20.81.44.00.7-0.70.70.3-1.41.2-1.12.01.6
Rest time, locomotor task time 20.60.82.11.4-1.40.7-0.2-0.50.7-0.50.80.8
Distance moved, locomotor task time 22.83.37.2-0.90.9-1.50.62.3-2.01.8-2.7-2.5
Vertical activity count, locomotor time 22.33.27.7-0.40.4-1.40.92.4-1.91.8-2.8-2.3
Light reinforcement 11.02.55.4-0.40.4-2.01.22.3-1.61.7-1.9-1.7
Light reinforcement 21.11.73.90.3-0.3-1.40.62.0-1.31.4-1.8-1.4
Bone: marrow area2.35.013.53.7-3.7-0.12.52.3-1.11.4-1.6-0.8
Bone: maximum diameter0.81.55.32.3-2.31.30.1-0.60.8-0.60.30.3
Bone: maximum force1.11.92.90.1-0.1-1.71.31.7-1.71.7-1.4-1.6
Bone: maximum moment0.71.32.20.2-0.2-1.31.01.5-1.41.3-1.2-1.3
Mean time between licks in bursts1.12.75.22.3-2.32.1-0.3-0.91.8-1.61.20.9
Mean num. licks in bursts1.11.86.9-2.62.6-1.1-0.20.0-0.80.5-0.1-0.4
Cd content in liver2.02.26.0-1.11.1-1.1-0.21.2-1.41.3-2.5-2.2
Co content in liver2.32.74.2-0.90.9-1.81.12.0-2.01.9-2.0-1.6
Cu content in liver1.31.54.5-2.12.1-0.1-0.9-1.30.4-0.61.10.8
Fe content in liver0.70.81.6-1.11.1-1.30.40.6-1.00.9-0.7-0.6
K content in liver0.70.72.5-0.20.20.6-1.6-0.60.9-0.91.00.4
Mg content in liver1.61.72.41.6-1.61.3-1.3-0.91.5-1.31.01.1
Mn content in liver1.51.76.72.6-2.60.9-0.50.30.6-0.4-0.30.1
Na content in liver0.60.62.1-0.70.70.0-0.2-0.80.6-0.61.51.1
Rb content in liver0.10.10.50.0-0.00.0-0.70.6-0.10.1-0.7-0.1
Se content in liver2.63.16.72.6-2.62.2-0.4-0.61.7-1.51.31.4
Sr content in liver0.60.51.30.8-0.8-0.00.10.6-0.60.5-1.1-1.0
Zn content in liver0.40.41.10.7-0.70.2-0.10.7-0.30.3-0.9-1.1
Bone: minimum diameter1.12.07.62.8-2.80.50.80.6-0.20.4-0.8-0.7
Time in familiar zone, hab. session 12.62.55.1-2.32.30.3-1.7-1.90.9-1.11.61.0
Time in novel zone, hab. session 12.12.13.61.8-1.8-0.31.91.8-0.91.1-1.4-1.3
Total zone transitions, hab. session 10.50.71.50.0-0.00.6-1.2-0.81.1-1.01.00.6
Total locomotion distance, hab. session 10.50.71.6-0.00.00.4-1.3-0.71.0-0.91.00.8
Locomotion velocity, hab. session 10.40.61.20.1-0.10.4-1.0-0.70.9-0.91.11.1
Time in familiar zone, hab. session 20.40.50.9-1.01.0-0.80.3-0.40.1-0.10.90.7
Time in novel zone, hab. session 20.40.41.10.3-0.30.40.30.8-0.60.5-1.0-1.0
Total zone transitions, hab. session 20.10.10.5-0.20.2-0.7-0.5-0.20.1-0.00.1-0.0
Total locomotion distance, hab. session 20.30.41.8-0.30.3-0.3-1.3-0.60.7-0.60.60.4
Locomotion velocity, hab. session 20.60.82.6-0.10.10.0-1.6-0.91.0-0.90.90.8
Novel to familiar place preference ratio0.10.10.5-0.00.00.7-0.6-0.10.3-0.40.10.4
Novelty place preference0.10.20.60.2-0.20.8-0.3-0.20.4-0.40.10.5
Time in novel zone, NPP test0.20.20.60.4-0.40.8-0.2-0.30.3-0.40.20.5
Total zone transitions, NPP test0.81.14.6-0.30.30.7-2.1-1.11.2-1.20.80.3
Total locomotion distance, NPP test0.50.74.4-0.70.70.1-2.1-0.60.5-0.5-0.1-0.3
Locomotion velocity, NPP test0.71.06.4-0.80.80.2-2.5-0.60.8-0.80.1-0.2
Intraocular pressure0.50.72.2-1.51.5-0.7-0.60.3-0.20.1-0.6-0.2
Delta distance traveled before/after self-admin0.40.42.80.4-0.40.31.7-0.3-0.20.20.10.1
Delta ambulatory time before/after self-admin0.40.53.00.6-0.60.61.7-0.1-0.10.20.10.0
Parametrial fat weight1.94.49.1-1.51.5-3.01.22.1-2.62.5-2.1-1.8
Pavlov. Cond. lever latency5.16.412.1-1.71.7-3.52.62.7-2.92.9-1.9-2.4
Pavlov. Cond. magazine entry latency3.74.87.41.6-1.62.7-1.4-2.52.4-2.42.22.5
Pavlov. Cond. change in total contacts1.92.13.71.4-1.41.9-0.6-1.51.5-1.41.21.8
Pavlov. Cond. index score4.96.110.12.0-2.03.2-2.1-2.72.7-2.72.12.5
Pavlov. Cond. latency score5.26.510.92.0-2.03.3-2.1-2.82.8-2.82.12.6
Pavlov. Cond. lever contacts3.54.27.91.9-1.92.8-2.3-2.02.2-2.21.11.7
Pavlov. Cond. magazine entry number2.73.45.2-1.41.4-2.31.32.0-2.12.0-1.8-2.0
Pavlov. Cond. intertrial magazine entries1.92.25.3-2.32.3-1.5-0.01.2-1.21.1-1.3-1.2
Pavlov. Cond. lever-magazine prob. diff.4.96.09.82.0-2.03.1-2.2-2.72.7-2.62.02.5
Pavlov. Cond. response bias3.34.16.71.7-1.72.6-1.8-2.12.3-2.21.72.1
Pavlov. Cond. lever latency0.60.91.71.1-1.1-0.40.91.1-0.60.7-1.3-0.8
Pavlov. Cond. magazine entry latency0.30.40.90.7-0.70.9-0.7-0.50.5-0.60.30.1
Pavlov. Cond. change in total contacts0.50.72.0-0.50.50.7-0.4-1.10.7-0.81.41.2
Pavlov. Cond. index score0.40.61.2-0.10.10.8-0.7-1.10.7-0.81.10.7
Pavlov. Cond. latency score0.30.41.0-0.20.20.6-0.5-1.00.5-0.61.00.6
Pavlov. Cond. lever contacts0.50.71.3-1.01.00.3-0.8-0.90.4-0.61.20.7
Pavlov. Cond. magazine entry number0.10.10.3-0.20.2-0.30.50.2-0.10.2-0.20.2
Pavlov. Cond. intertrial magazine entries0.71.12.00.8-0.81.10.0-1.01.3-1.11.01.4
Pavlov. Cond. lever-magazine prob. diff.0.40.51.1-0.10.10.7-0.7-1.00.6-0.71.00.6
Pavlov. Cond. response bias0.60.81.6-0.30.30.8-1.1-1.10.8-1.01.30.8
Time in closed arm before self-admin0.10.20.40.6-0.60.40.20.20.1-0.1-0.5-0.4
Time in closed arm after self-admin0.10.10.10.3-0.3-0.30.10.3-0.20.2-0.00.3
Time in open arm before self-admin1.11.22.50.2-0.21.3-0.7-0.91.2-1.31.61.5
Time in open arm after self-admin0.50.51.2-0.10.11.1-0.4-1.10.7-0.80.80.6
Bone: periosteal estimation1.12.46.82.6-2.6-0.32.01.3-0.81.0-0.8-0.5
Bone: periosteal perimeter0.71.14.52.1-2.10.50.90.30.10.1-0.0-0.0
Bone: post-yield work0.60.82.41.6-1.60.40.00.9-0.10.2-0.8-0.9
Progressive ratio test 1 active lever presses0.10.20.7-0.10.1-0.2-0.70.5-0.10.0-0.80.0
Progressive ratio test 1 breakpoint0.10.20.7-0.00.0-0.1-0.60.5-0.10.0-0.8-0.0
Progressive ratio test 1 inactive lever presses0.50.71.5-1.01.0-1.2-0.40.3-0.70.6-1.1-0.6
Progressive ratio test 2 active lever presses0.40.41.3-0.70.70.2-1.2-0.60.5-0.60.20.6
Progressive ratio test 2 breakpoint0.40.51.4-0.80.80.2-1.2-0.70.5-0.60.40.7
Progressive ratio test 2 inactive lever presses0.20.41.30.5-0.50.8-1.1-0.00.5-0.5-0.7-0.0
Incentive Sensitization - Responses0.71.12.0-0.30.30.8-1.0-1.41.1-1.01.31.3
Incentive Sensitization - Breakpoint0.81.12.1-0.50.50.7-1.1-1.51.0-1.01.31.3
Sum of active levers in priming session hrs 5-60.50.41.30.6-0.61.2-0.4-0.10.7-0.70.50.7
Progressive ratio2.23.59.5-0.50.5-2.63.11.8-2.32.3-0.8-0.5
Food seeking constrained by brief footshock0.10.10.5-0.70.7-0.1-0.20.4-0.1-0.10.3-0.1
Seeking ratio, punishment vs. effort1.72.45.50.4-0.42.3-2.2-1.22.0-2.11.00.5
Retroperitoneal fat weight0.20.81.6-0.60.6-1.30.00.6-1.11.1-1.2-0.7
Reaction time number correct0.61.22.1-1.51.5-1.41.00.8-1.11.1-0.5-0.7
Reaction time mean minus median0.71.84.71.1-1.12.2-1.4-1.11.6-1.50.60.9
Reaction time mean minus median AUC0.81.95.90.9-0.92.4-2.0-0.81.5-1.60.20.6
Reaction time num false alarms0.50.81.61.3-1.30.40.5-0.30.7-0.60.91.2
Reaction time num false alarms AUC0.71.12.01.4-1.40.40.9-0.40.8-0.61.21.4
Reaction time trials correct on left0.61.22.1-1.51.5-1.41.00.8-1.11.1-0.5-0.7
Reaction time trials on left0.61.21.9-1.41.4-1.31.00.8-1.11.1-0.5-0.7
Reaction time mean0.91.43.11.6-1.61.8-1.4-0.40.9-0.8-0.60.0
Reaction time mean AUC0.81.22.81.5-1.51.7-1.5-0.40.8-0.8-0.60.0
Median of all reaction times0.60.92.01.4-1.41.2-1.1-0.10.4-0.3-0.9-0.3
Reaction time omissions0.60.81.71.3-1.31.1-1.1-0.51.0-0.80.0-0.1
Reaction time false alarm rate1.72.34.72.2-2.21.40.2-0.91.5-1.31.41.8
Reaction time premature initiation rate0.30.41.50.0-0.0-0.20.40.7-0.60.6-0.9-1.2
Reaction time premature initiations0.81.52.5-0.80.8-1.11.21.3-1.41.3-1.2-1.6
Std. dev. reaction times1.32.46.11.9-1.92.5-1.2-1.11.6-1.50.50.9
Reaction time trials completed0.61.21.9-1.41.4-1.31.00.8-1.11.1-0.5-0.7
Reaction time trials AUC0.71.21.9-1.41.4-1.41.00.9-1.21.1-0.6-0.9
Run reversals in cocaine runway, females0.50.51.1-1.01.0-1.0-0.20.3-0.70.5-0.7-0.5
Run reversals in cocaine runway, males0.50.51.00.7-0.70.7-0.8-0.51.0-0.90.70.1
Latency to leave start box in cocaine runway0.40.51.21.1-1.11.1-0.5-0.30.5-0.4-0.2-0.0
Latency to leave start box in cocaine runway, F0.20.30.60.7-0.70.8-0.50.00.5-0.5-0.30.1
Latency to leave start box in cocaine runway, M0.20.20.50.7-0.70.30.1-0.2-0.10.1-0.1-0.5
Std. dev. time between licks in bursts2.23.09.13.0-3.01.80.4-1.01.4-1.10.80.9
Total sessions with >9 infusions0.10.10.5-0.40.4-0.1-0.30.20.1-0.30.00.7
Short access day 1 total inactive lever presses0.30.40.90.9-0.90.9-0.70.50.3-0.4-0.30.1
Short access day 10 total inactive lever presses0.10.30.80.4-0.4-0.2-0.3-0.60.6-0.40.80.9
Short access day 1 total infusions0.20.20.80.0-0.00.9-0.80.30.3-0.5-0.40.4
Short access day 10 total infusions0.30.41.2-0.80.8-0.3-1.1-0.20.2-0.30.00.9
Short access total infusions0.20.20.8-0.50.50.2-0.90.20.1-0.3-0.40.5
Short access day 1 locomotion0.40.51.80.1-0.10.3-0.9-0.50.8-0.80.41.3
Short access day 10 total locomotion1.12.15.81.8-1.8-1.32.41.6-0.71.0-0.6-1.0
Short access total locomotion0.50.61.21.0-1.0-0.50.71.1-0.40.4-0.9-0.5
One hour access (0.3 mA shock)1.31.52.7-0.40.40.4-1.6-1.61.3-1.31.41.6
Compulsive drug intake0.70.82.51.6-1.60.3-0.3-0.41.0-0.70.6-0.1
One hour access (shock baseline)0.60.92.6-1.61.60.2-1.0-0.70.1-0.40.41.0
Social response proportion0.60.72.01.2-1.2-0.41.40.7-0.60.7-0.50.2
Social responses0.40.52.00.8-0.8-0.41.40.6-0.30.40.10.8
Social time1.21.64.32.1-2.10.70.1-0.31.4-1.01.11.3
Soleus weight1.75.018.84.3-4.30.91.31.6-0.10.4-1.2-0.9
Bone: stiffness0.81.43.0-0.40.4-1.70.91.5-1.31.3-1.1-1.1
Tibialis anterior weight0.30.82.3-1.51.5-1.50.20.4-0.60.60.10.4
Time to tail flick, vehicle, before self-admin0.20.20.8-0.40.4-0.9-0.0-0.50.10.00.7-0.4
Time to tail flick, vehicle, after self-admin0.20.30.60.6-0.60.8-0.4-0.30.6-0.60.20.1
Time to tail flick, test, before self-admin0.80.83.0-0.70.7-0.20.2-1.10.7-0.61.71.1
Time to tail flick, test, after self-admin2.93.05.4-0.60.61.4-1.7-2.31.9-1.92.22.0
Delta time to tail flick, vehicle, before/after SA0.70.71.9-0.30.31.3-1.4-0.60.7-0.90.30.7
Delta time to tail flick, test, before/after SA0.30.31.8-0.50.50.3-1.4-0.50.3-0.4-0.10.2
Tibia length1.33.59.53.1-3.1-0.62.02.0-0.91.2-1.0-0.3
Ambulatory time before self-admin0.00.10.30.1-0.1-0.5-0.40.3-0.00.10.10.3
Ambulatory time after self-admin0.40.42.00.7-0.7-0.31.40.3-0.40.6-0.10.2
Bone: tissue strength0.60.61.4-0.30.3-0.40.11.0-0.80.7-1.2-1.1
Total heroin consumption0.20.31.20.4-0.40.20.2-0.40.5-0.30.51.1
Bone: trabecular number1.42.34.7-2.22.20.3-2.2-1.81.0-1.20.80.6
Bone: trabecular spacing1.72.34.81.8-1.8-0.52.21.9-1.31.4-1.1-0.8
Bone: trabecular thickness0.91.12.9-1.71.7-0.3-1.7-1.00.4-0.50.2-0.2
Bone: trabecular tissue density0.40.61.60.6-0.61.10.1-0.10.7-0.70.91.3
Water consumed over 24 hours0.10.20.80.9-0.90.30.00.00.1-0.0-0.0-0.1
Number of responses in last shaping day1.31.44.32.1-2.11.51.10.60.2-0.2-0.30.1