Hub : Genes

Rrp36

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Rrp36 0.11 0.07 6.9e-06 0.04 0.09 0.08 0.08 2.2e-03 2.4e-05 7.7e-05 4.0e-05
2 PL mRNA stability Rrp36 0.04 0.03 5.1e-05 0.03 0.04 0.03 0.03 2.2e-04 6.0e-05 7.4e-04 1.3e-04
3 Liver gene expression Rrp36 0.43 0.13 0.0e+00 0.42 0.43 0.42 0.42 5.6e-50 2.8e-51 9.0e-51 3.6e-51
4 BLA gene expression Rrp36 0.44 0.12 0.0e+00 0.52 0.51 0.51 0.52 1.5e-31 4.7e-31 3.3e-31 7.7e-32
5 LHb gene expression Rrp36 0.45 0.15 2.8e-09 0.29 0.28 0.31 0.31 1.2e-07 2.5e-07 5.0e-08 5.2e-08
6 PL gene expression Rrp36 0.5 0.13 0.0e+00 0.58 0.61 0.61 0.62 8.9e-79 2.3e-84 1.3e-84 6.4e-86
7 Adipose mRNA stability Rrp36 0.05 0.03 1.8e-07 0.06 0.05 0.04 0.05 8.1e-07 3.2e-06 1.1e-05 3.5e-06
8 Brain gene expression Rrp36 0.65 0.14 0.0e+00 0.55 0.55 0.55 0.56 1.4e-60 2.5e-61 1.2e-61 9.9e-62
9 Brain mRNA stability Rrp36 0.1 0.06 6.6e-10 0.1 0.09 0.09 0.09 6.1e-10 4.4e-09 5.1e-09 9.4e-09
10 pVTA gene expression Rrp36 0.72 0.13 0.0e+00 0.49 0.49 0.49 0.5 6.9e-45 4.7e-45 5.9e-45 8.6e-46
11 OFC gene expression Rrp36 0.54 0.17 1.2e-11 0.44 0.41 0.41 0.41 8.2e-12 6.3e-11 9.9e-11 5.6e-11
12 IL gene expression Rrp36 0.43 0.17 2.9e-08 0.32 0.24 0.18 0.29 1.8e-08 1.7e-06 4.3e-05 9.2e-08
13 NAcc gene expression Rrp36 0.41 0.11 0.0e+00 0.57 0.58 0.58 0.58 1.4e-106 1.6e-107 3.0e-109 2.7e-109
14 pVTA mRNA stability Rrp36 0.08 0.05 7.2e-07 0.08 0.07 0.07 0.07 7.6e-07 2.8e-06 4.4e-06 2.4e-06
15 Eye gene expression Rrp36 0.27 0.15 3.1e-03 0.13 0.04 -0 0.06 4.8e-03 9.5e-02 3.3e-01 4.6e-02
16 IC gene expression Rrp36 0.58 0.14 0.0e+00 0.38 0.39 0.4 0.4 3.9e-17 1.2e-17 6.3e-18 5.1e-18
17 IC mRNA stability Rrp36 0.14 0.09 3.6e-05 0.11 0.1 0.1 0.1 2.7e-05 6.4e-05 4.4e-05 5.6e-05
18 Adipose gene expression Rrp36 0.45 0.12 0.0e+00 0.46 0.46 0.45 0.46 2.2e-56 2.5e-56 8.1e-55 2.5e-56
19 NAcc mRNA stability Rrp36 0.03 0.02 1.2e-05 0.03 0.03 0.03 0.03 2.1e-05 1.0e-05 3.5e-05 2.2e-05
20 RMTg gene expression Rrp36 0.6 0.19 1.1e-05 0.18 0.19 0.11 0.17 2.0e-05 9.1e-06 9.4e-04 2.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.61.02.0-1.4-1.4-0.8-0.9-1.0-1.0-0.9-0.9-1.0-0.8-0.8-0.9-0.9-0.9-1.0-0.9-0.9-1.0-0.4-1.4
Area under the delay curve8.29.611.1-2.7-2.7-3.2-3.2-3.2-3.1-3.2-3.2-3.1-3.2-3.1-3.3-3.2-3.1-3.1-3.0-3.0-3.1-3.3-2.6
BMI with tail3.813.315.43.93.93.63.73.73.73.73.73.73.53.63.73.73.53.53.63.63.63.23.6
BMI without tail5.316.216.94.14.14.14.14.14.14.14.14.13.94.04.14.13.93.94.14.13.93.93.7
Body weight4.720.822.34.54.54.74.64.64.64.64.64.64.64.64.74.64.64.44.54.54.54.63.8
Weight adjusted by age0.40.60.90.70.70.80.60.80.70.60.70.80.80.80.60.80.80.90.90.90.80.70.9
Bone surface1.52.84.6-2.0-2.1-1.5-1.6-1.6-1.7-1.6-1.5-1.6-1.6-1.6-1.6-1.6-1.7-1.8-1.6-1.6-1.7-1.1-2.1
Bone volume0.81.42.4-1.5-1.5-1.0-1.1-1.1-1.2-1.1-1.1-1.1-1.1-1.0-1.1-1.1-1.1-1.2-1.1-1.1-1.2-0.7-1.6
Breakpoint value in progressive ratio session0.00.00.10.20.2-0.2-0.0-0.2-0.1-0.0-0.2-0.2-0.2-0.2-0.0-0.1-0.20.0-0.2-0.2-0.0-0.40.1
Number of licking bursts3.04.96.51.71.82.32.22.22.22.22.32.22.32.22.22.32.32.22.22.22.22.52.2
Context. condit. distance diff. score0.20.20.40.40.30.60.40.40.40.40.40.40.50.50.50.40.50.40.50.50.40.6-0.1
Locomotion velocity, session 10.50.51.21.11.10.60.70.70.70.70.70.70.60.70.70.70.60.80.70.70.80.30.8
Locomotion distance, session 12.22.83.31.81.71.71.71.71.71.71.71.71.61.61.71.71.61.71.71.71.71.61.3
Locomotion velocity, session 25.46.29.13.02.92.52.42.42.52.42.42.42.42.42.42.52.52.62.72.72.62.12.0
Locomotion distance, session 21.31.82.51.61.51.31.41.41.41.41.41.41.31.31.41.31.31.41.31.31.31.11.2
Locomotion velocity, session 30.50.51.31.11.10.70.70.70.70.60.60.70.60.60.70.70.70.70.80.80.70.30.7
Locomotion distance, session 30.91.01.6-0.7-0.7-1.1-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.1-1.0-1.0-1.0-1.3-0.9
Stereotopy head waving bouts, day 31.61.92.21.21.31.31.41.41.41.51.41.41.41.41.31.41.41.31.21.21.21.31.5
Stereotopy head waving duration, day 32.32.73.51.71.81.61.71.71.71.71.71.71.61.71.61.71.61.61.51.51.51.41.9
Locomotion velocity, session 70.10.20.60.80.80.30.30.30.40.30.30.30.30.40.40.30.40.30.30.30.3-0.10.4
Locomotion distance, session 70.00.10.30.50.50.10.20.20.20.20.10.10.20.20.30.20.20.10.20.20.1-0.20.3
Stereotopy head waving bouts, day 70.10.10.30.20.20.50.40.40.40.40.50.40.40.40.30.40.40.40.30.30.30.60.2
Stereotopy head waving duration, day 70.00.00.1-0.3-0.3-0.0-0.1-0.1-0.1-0.1-0.0-0.0-0.1-0.1-0.2-0.1-0.1-0.0-0.1-0.1-0.10.2-0.3
Locomotion velocity, session 80.40.50.90.90.80.80.60.60.70.60.60.60.70.60.70.70.70.80.90.90.90.60.3
Locomotion distance, session 81.01.41.71.31.21.31.21.21.21.21.21.21.21.21.31.21.21.21.21.21.11.20.7
Degree of sensitization distance1.91.92.31.51.51.41.41.41.41.41.41.41.41.41.51.41.41.41.31.31.31.21.4
Degree of sensitization stereotypy0.50.51.0-0.8-0.8-0.6-0.7-0.6-0.7-0.7-0.6-0.6-0.6-0.6-0.8-0.7-0.6-0.7-0.7-0.7-0.8-0.5-1.0
Conditioned locomotion2.22.54.1-1.2-1.2-1.7-1.6-1.6-1.6-1.6-1.7-1.6-1.6-1.7-1.5-1.6-1.6-1.7-1.6-1.6-1.7-2.0-1.2
Cocaine response after cond. corrected0.10.20.3-0.5-0.5-0.5-0.4-0.4-0.5-0.4-0.4-0.4-0.5-0.4-0.4-0.4-0.5-0.5-0.5-0.5-0.5-0.4-0.2
Cocaine response after cond. not corrected0.30.40.6-0.6-0.6-0.7-0.6-0.6-0.7-0.6-0.6-0.6-0.7-0.7-0.6-0.7-0.7-0.6-0.6-0.6-0.6-0.7-0.4
Cocaine response before conditioning0.00.00.10.30.3-0.00.00.00.0-0.00.00.0-0.1-0.10.10.0-0.00.20.10.10.3-0.20.2
Saline control response0.00.00.10.20.1-0.0-0.0-0.0-0.1-0.0-0.1-0.1-0.0-0.1-0.1-0.0-0.0-0.10.10.10.0-0.1-0.3
Bone: connectivity density1.01.63.4-1.8-1.8-1.1-1.2-1.2-1.3-1.2-1.1-1.2-1.1-1.1-1.1-1.2-1.2-1.3-1.2-1.2-1.2-0.6-1.5
Bone: cortical apparent density0.50.70.9-0.6-0.7-0.8-0.9-0.9-0.9-0.9-0.9-1.0-0.8-0.9-0.8-0.9-0.8-0.8-0.8-0.8-0.8-0.9-1.0
Bone: cortical area0.50.71.91.41.21.00.80.80.90.80.80.90.80.80.70.80.90.80.80.80.70.60.1
Bone: cortical porosity0.10.10.20.20.20.30.40.40.30.40.40.40.30.40.30.30.30.30.30.30.30.40.4
Bone: cortical porosity0.10.10.30.30.40.30.40.40.40.50.40.40.30.40.30.40.30.20.20.20.20.20.5
Bone: cortical thickness0.50.82.21.51.31.00.90.80.90.80.80.80.90.90.80.90.90.90.90.90.90.60.2
Bone: cortical thickness0.00.10.2-0.3-0.3-0.1-0.2-0.2-0.2-0.3-0.2-0.2-0.1-0.2-0.1-0.2-0.1-0.2-0.2-0.2-0.20.0-0.5
Bone: cortical tissue density0.60.81.0-0.7-0.7-0.9-0.9-1.0-0.9-0.9-1.0-1.0-0.9-0.9-0.8-0.9-0.9-0.8-0.8-0.8-0.8-0.9-0.9
Condit. Reinf. active minus inactive responses1.71.92.21.41.41.41.41.41.41.41.41.41.41.41.41.41.41.51.41.41.41.31.4
Condit. Reinf. active-inactive response ratio0.30.30.50.40.40.60.60.60.60.60.60.60.60.60.60.60.50.60.60.60.50.70.6
Condit. Reinf. active responses2.93.74.01.91.92.01.91.91.91.91.91.91.91.92.01.91.92.01.91.91.91.91.6
Condit. Reinf. inactive responses2.32.83.21.71.61.81.71.71.71.71.71.71.71.71.81.71.71.71.61.61.61.71.4
Incentive salience index mean2.22.83.71.91.81.71.61.61.71.61.61.61.71.61.71.71.71.71.71.71.61.51.4
Condit. Reinf. lever presses3.85.37.02.62.52.42.32.32.42.32.32.32.32.32.32.32.32.32.32.32.22.11.8
Condit. Reinf. active minus inactive responses0.10.10.3-0.1-0.00.20.20.20.20.20.20.20.20.20.10.20.10.40.40.40.40.50.2
Condit. Reinf. active-inactive response ratio0.91.01.80.60.61.01.00.90.90.91.01.00.90.90.91.00.91.31.31.31.21.31.0
Condit. Reinf. active responses0.00.00.1-0.0-0.00.10.10.10.10.10.10.10.00.1-0.00.10.00.20.20.20.20.30.1
Condit. Reinf. inactive responses0.00.10.20.0-0.0-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.3-0.2-0.2-0.3-0.3-0.3-0.3-0.4-0.3
Condit. Reinf. lever presses0.60.81.30.70.71.00.91.00.90.91.01.00.91.00.81.00.90.91.01.00.91.20.7
Condit. Reinf. lever reinforcers received0.00.00.0-0.1-0.10.10.0-0.0-0.0-0.0-0.0-0.0-0.00.0-0.10.0-0.00.20.10.10.10.2-0.0
Conditioned reinforcement - actives0.30.51.2-0.0-0.1-0.7-0.6-0.6-0.6-0.6-0.7-0.6-0.7-0.6-0.7-0.7-0.7-0.7-0.8-0.8-0.7-1.1-0.6
Conditioned reinforcement - inactives0.30.40.70.90.80.60.70.70.60.70.70.70.80.70.70.60.80.40.50.30.50.40.6
Conditioned locomotion0.20.30.40.50.50.50.60.60.50.60.60.60.60.60.50.50.60.40.30.30.50.50.5
Patch foraging indifference point 0 sec0.81.51.71.11.21.21.21.21.21.11.21.21.31.31.11.21.31.21.31.31.11.21.3
Patch foraging indifference point AUC0.60.82.11.51.40.80.80.80.90.80.80.80.80.80.80.80.80.90.90.90.90.31.0
Delay disc. indifference point, 0s delay1.82.02.8-1.4-1.2-1.7-1.5-1.5-1.5-1.5-1.5-1.5-1.4-1.5-1.5-1.5-1.3-1.4-1.2-1.2-1.3-1.6-0.4
Delay disc. indifference point, 16s delay11.712.914.0-3.2-3.3-3.6-3.6-3.7-3.6-3.7-3.7-3.6-3.7-3.6-3.7-3.6-3.7-3.5-3.5-3.5-3.6-3.7-3.3
Delay disc. indifference point, 2s delay3.43.74.6-1.7-1.7-2.1-2.1-2.1-1.9-2.1-2.1-2.1-2.0-2.1-2.1-2.0-1.9-1.8-1.8-1.8-1.8-2.1-1.3
Delay disc. indifference point, 24s delay1.21.31.6-1.2-1.2-1.1-1.2-1.2-1.2-1.2-1.2-1.3-1.2-1.3-1.2-1.1-1.2-0.9-0.9-0.9-1.0-1.0-1.3
Delay disc. indifference point, 4s delay3.33.55.8-1.2-1.2-2.0-2.0-1.9-1.9-2.0-1.9-1.8-1.9-1.8-2.0-2.0-1.8-2.1-1.9-1.9-2.0-2.4-1.4
Delay disc. indifference point, 8s delay4.85.66.7-2.0-2.0-2.4-2.5-2.4-2.4-2.5-2.4-2.4-2.4-2.4-2.5-2.4-2.4-2.4-2.4-2.4-2.4-2.6-2.1
Indifference point function ln k0.40.71.0-1.0-0.9-1.0-0.8-0.8-0.8-0.8-0.8-0.8-0.9-0.8-0.7-0.8-0.9-0.8-0.9-0.9-0.9-0.9-0.4
Indifference point function log k0.40.71.0-1.0-0.9-1.0-0.8-0.8-0.8-0.8-0.8-0.8-0.9-0.8-0.7-0.8-0.9-0.8-0.9-0.9-0.9-0.9-0.4
Patch foraging total patch changes 0 sec1.01.92.21.31.41.41.31.31.41.31.31.41.41.51.31.41.41.31.41.41.21.31.5
Patch foraging total patch changes 12 sec0.91.22.71.61.51.11.01.01.10.91.01.01.11.10.91.01.21.01.11.00.90.70.8
Patch foraging total patch changes 18 sec1.11.73.11.71.71.31.21.21.41.21.21.21.31.31.21.31.31.31.31.31.10.91.3
Patch foraging total patch changes 24 sec0.50.91.61.31.21.00.90.91.00.90.91.01.01.01.01.01.00.80.90.90.90.70.9
Patch foraging total patch changes 6 sec2.33.64.62.22.12.01.81.91.91.81.81.91.92.01.81.92.01.91.91.91.91.71.5
Patch foraging time to switch 0 sec3.57.19.7-3.0-3.1-2.5-2.6-2.7-2.8-2.6-2.6-2.7-2.5-2.7-2.6-2.6-2.5-2.6-2.6-2.6-2.6-2.0-3.1
Patch foraging water rate 0 sec1.83.97.62.82.81.81.91.92.11.91.81.91.91.91.91.91.91.71.81.81.71.02.4
Patch foraging water rate 12 sec3.98.110.03.23.22.82.92.92.92.92.92.92.82.82.92.82.82.72.72.72.82.42.8
Patch foraging water rate 18 sec1.21.82.31.51.51.31.31.31.41.31.31.31.31.41.31.31.41.21.31.31.31.11.5
Patch foraging water rate 24 sec2.02.74.01.81.91.51.71.71.71.71.71.71.61.71.51.61.71.61.51.51.61.32.0
Patch foraging water rate 6 sec0.20.30.90.90.90.40.50.50.60.50.50.50.40.50.50.50.40.40.40.50.40.00.8
Seeking ratio, delayed vs. immediate footshock1.92.32.9-1.7-1.7-1.5-1.5-1.5-1.6-1.5-1.5-1.4-1.5-1.4-1.5-1.5-1.5-1.6-1.5-1.5-1.6-1.3-1.6
Distance traveled before self-admin0.00.10.10.30.30.20.30.20.20.20.30.20.30.20.30.20.40.00.10.10.10.00.2
Distance traveled after self-admin2.22.73.71.71.81.51.71.71.61.61.71.71.61.61.61.71.61.51.71.71.61.41.9
Extensor digitorum longus weight0.10.30.70.70.70.60.60.60.60.60.50.50.60.60.90.50.60.50.60.60.60.40.4
Bone: elastic displacement0.60.70.9-0.7-0.8-0.8-0.9-0.9-0.8-0.9-0.9-0.9-0.8-0.9-0.9-0.8-0.8-0.6-0.6-0.6-0.6-0.7-0.9
Bone: elastic work0.00.00.50.1-0.10.2-0.1-0.1-0.0-0.1-0.1-0.10.1-0.1-0.10.00.10.10.20.20.10.3-0.7
Bone: endosteal estimation0.40.81.2-1.1-1.0-0.9-0.8-0.8-0.9-0.8-0.8-0.8-0.9-0.8-0.9-0.9-0.9-1.1-1.0-1.0-1.0-0.8-0.8
Bone: endosteal perimeter0.00.00.10.20.20.30.30.30.20.30.30.30.20.30.10.20.30.00.10.10.10.2-0.0
Epididymis fat weight3.010.112.02.92.93.43.23.33.23.23.33.33.33.33.33.23.33.23.03.13.13.52.4
Delta time in closed arm before/after self-admin0.10.10.3-0.6-0.60.10.10.1-0.10.10.10.10.10.00.10.10.0-0.20.10.1-0.00.5-0.4
Delta time in open arm before/after self-admin0.10.10.4-0.10.0-0.4-0.4-0.3-0.2-0.5-0.3-0.2-0.3-0.2-0.4-0.3-0.2-0.2-0.4-0.4-0.4-0.60.3
Diff in mean of infusions in LGA sessions0.70.81.31.11.20.80.90.91.00.90.90.90.90.91.00.90.90.80.80.80.90.61.1
Delay discount exponential model param8.39.310.62.62.73.13.23.23.13.23.23.13.13.13.23.13.13.02.92.93.03.32.7
Extinction: sum of active levers before priming0.00.00.30.30.4-0.00.10.10.20.10.10.1-0.00.10.00.10.00.00.00.00.2-0.20.6
Active lever presses in extinction session 60.20.20.70.70.70.30.40.30.50.40.40.30.30.40.30.40.30.40.30.30.50.00.8
Bone: final force0.40.61.01.00.81.00.80.80.90.80.80.80.90.90.70.80.90.70.70.70.70.9-0.0
Bone: final moment0.30.51.11.00.80.90.70.70.80.70.70.70.80.80.60.70.80.60.70.70.60.7-0.0
Food consumed during 24 hour testing period0.40.61.21.01.00.70.70.70.80.70.70.70.70.70.70.70.80.80.80.80.80.41.1
Glucose7.111.212.03.33.33.43.43.43.43.43.43.43.43.33.53.43.33.43.43.43.23.33.1
Heart weight0.10.20.50.70.60.50.40.40.40.40.40.50.40.40.30.40.40.30.40.40.30.30.0
Delay discount hyperbolic model param7.48.39.52.52.52.93.03.02.93.03.02.92.92.93.12.92.92.92.82.82.93.12.5
Intermittent access intake day 1-15 change0.00.00.10.30.20.10.20.10.10.20.10.00.10.0-0.00.10.10.10.10.10.10.0-0.1
Intermittent access intake escalation0.00.00.00.10.10.10.10.00.00.10.0-0.0-0.0-0.0-0.10.00.0-0.0-0.00.00.00.0-0.2
Intermittent access intake escalation 20.10.10.2-0.0-0.1-0.2-0.3-0.3-0.3-0.2-0.3-0.3-0.3-0.3-0.4-0.3-0.3-0.3-0.4-0.3-0.3-0.4-0.4
Intermitt. access day 1 inactive lever presses0.31.32.00.70.71.21.21.11.11.31.11.11.21.11.21.21.21.11.11.11.31.41.0
Intermitt. access day 15 inactive lever presses0.30.71.20.70.70.81.00.90.71.10.80.90.90.91.10.80.80.70.70.70.80.90.7
Intermitt. access escalation Index0.00.00.0-0.2-0.1-0.1-0.1-0.1-0.0-0.1-0.0-0.1-0.1-0.10.0-0.0-0.10.0-0.1-0.1-0.2-0.10.1
Intermittent access day 1 total infusions0.60.91.20.80.90.91.11.11.01.11.11.11.01.11.11.01.00.80.80.70.80.90.9
Intermittent access day 15 total infusions0.40.61.00.70.70.70.90.90.71.00.90.90.80.90.80.70.80.50.50.50.60.70.6
Intermittent access terminal intake (last 3 days)0.00.00.10.10.10.10.30.30.10.40.30.20.10.30.20.10.1-0.1-0.1-0.2-0.10.0-0.1
Intermittent access total infusions0.20.20.50.40.50.40.60.60.40.70.60.60.50.60.60.40.50.30.20.20.30.40.4
Intermittent access day 1 locomotion1.01.21.60.90.91.11.21.21.11.21.31.21.21.21.21.11.10.90.90.91.01.11.0
Intermittent access day 15 total locomotion0.81.41.81.21.21.21.31.31.21.31.31.31.31.31.11.21.31.01.11.11.01.11.0
Intermittent access total locomotion0.80.91.30.70.80.91.11.10.91.11.11.11.11.11.01.01.10.80.80.80.81.00.9
Intermittent access standard deviation1.32.73.8-1.9-1.9-1.6-1.6-1.6-1.7-1.5-1.6-1.6-1.6-1.6-1.6-1.7-1.6-1.7-1.7-1.6-1.7-1.3-2.0
Left kidney weight1.67.48.93.02.92.82.82.72.82.82.72.72.82.72.72.72.82.72.72.72.62.52.3
Right kidney weight1.56.99.93.13.12.62.62.62.72.52.62.62.62.62.52.62.72.52.62.62.52.12.5
Cocaine induced anxiety0.10.10.3-0.1-0.00.30.40.30.30.40.30.30.30.30.20.30.30.30.40.40.30.60.2
Post-drug Anxiety0.00.00.2-0.1-0.10.20.20.10.20.20.10.10.10.10.10.20.00.30.30.30.30.5-0.0
Baseline Anxiety0.50.60.9-0.4-0.5-0.8-0.8-0.8-0.7-0.8-0.9-0.8-0.9-0.8-0.6-0.8-0.9-0.7-0.7-0.7-0.7-0.9-0.8
Tail length1.45.47.12.12.02.52.32.32.32.32.42.32.42.32.42.42.42.42.42.42.32.71.6
Length with tail1.04.57.41.71.62.42.22.22.12.22.22.12.32.22.22.22.22.12.12.22.22.71.2
Length without tail0.62.02.91.31.11.61.41.51.41.51.51.41.51.41.51.41.41.41.41.41.51.70.5
Times rat made contact with spout5.36.17.02.22.32.52.42.42.52.42.42.32.52.62.42.52.52.62.62.62.62.62.5
Lifetime Intake0.00.00.1-0.1-0.1-0.10.10.0-0.10.10.00.0-0.10.0-0.0-0.1-0.1-0.3-0.4-0.4-0.3-0.2-0.1
Liver weight, left0.20.31.11.00.90.40.50.40.50.50.40.40.40.40.50.40.40.50.50.50.40.00.3
Liver weight, right2.44.35.52.42.22.22.02.02.12.02.11.92.12.02.12.12.12.12.12.12.12.01.3
Locomotor activity2.43.85.11.91.72.11.91.81.81.81.81.82.01.91.91.92.02.12.22.22.32.11.3
Locomotor testing distance2.23.95.11.81.72.11.91.91.81.91.91.92.02.02.02.02.02.22.22.22.32.21.2
Locomotor testing rearing2.44.86.12.52.42.22.12.12.22.12.12.22.22.22.12.12.22.42.22.22.31.92.1
Locomotion in novel chamber0.91.11.3-0.9-0.9-1.0-1.1-1.1-1.0-1.1-1.0-1.0-1.1-1.0-1.1-1.1-1.0-1.2-1.2-1.2-1.2-1.1-1.1
Locomotion in novel chamber post-restriction0.50.91.9-0.4-0.4-1.0-0.9-0.9-0.9-0.9-0.9-0.9-1.1-0.9-0.8-1.0-1.1-1.1-1.1-1.1-1.1-1.4-0.6
Fecal boli incidents, locomotor time 10.30.41.1-0.0-0.1-0.7-0.7-0.7-0.6-0.7-0.7-0.6-0.7-0.6-0.7-0.7-0.6-0.8-0.7-0.7-0.7-1.0-0.5
Change in fecal boli incidents, locomotor task0.10.10.3-0.2-0.2-0.4-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.5-0.0
Time >=10cm from walls, locomotor time 10.30.30.60.70.80.50.50.60.60.50.60.70.60.70.60.50.70.40.40.40.40.30.8
Bouts of movement, locomotor time 10.00.10.4-0.6-0.4-0.2-0.0-0.0-0.1-0.00.00.00.00.0-0.0-0.20.0-0.3-0.4-0.4-0.20.10.3
Total resting periods, locomotor time 10.20.20.6-0.00.10.40.50.50.40.50.50.60.60.60.50.40.60.20.20.20.40.60.8
Rest time, locomotor task time 10.60.81.3-1.0-0.9-0.9-0.9-0.8-0.9-0.9-0.8-0.8-0.8-0.8-0.9-0.9-0.8-1.0-1.1-1.1-1.0-0.9-0.5
Distance moved, locomotor task time 10.00.10.20.20.20.30.20.20.20.20.20.30.30.30.20.30.30.30.40.40.30.40.0
Vertical activity count, locomotor time 10.30.71.2-0.6-0.7-0.8-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.7-0.6-0.6-0.7-0.7-1.1
Time >=10cm from walls, locomotor time 20.40.61.00.91.00.70.70.80.80.70.80.90.80.90.80.70.90.50.40.40.60.41.0
Bouts of movement, locomotor time 20.20.30.50.40.40.60.60.60.50.60.60.70.70.70.60.50.70.50.50.50.50.60.5
Total resting periods, locomotor time 20.00.10.1-0.00.00.20.20.30.10.20.30.40.40.40.20.20.40.20.20.20.10.30.2
Rest time, locomotor task time 20.50.61.1-1.1-1.0-0.8-0.7-0.7-0.8-0.7-0.7-0.7-0.7-0.7-0.8-0.8-0.7-1.0-0.9-0.9-0.8-0.6-0.5
Distance moved, locomotor task time 21.21.41.71.11.21.11.11.21.21.11.21.21.21.21.21.21.21.21.11.11.21.11.3
Vertical activity count, locomotor time 20.10.10.2-0.1-0.2-0.4-0.4-0.4-0.3-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.4-0.2-0.3-0.3-0.3-0.5-0.3
Light reinforcement 11.43.54.62.22.11.91.91.91.91.81.81.91.91.91.81.91.91.91.91.91.81.61.8
Light reinforcement 22.33.54.51.61.62.02.02.01.92.02.01.91.92.01.91.91.91.81.91.91.82.11.5
Bone: marrow area0.40.91.2-1.1-1.1-0.9-0.9-0.8-0.9-0.8-0.8-0.8-0.9-0.8-0.9-0.9-0.9-1.1-1.0-1.0-1.1-0.8-0.9
Bone: maximum diameter0.20.41.01.00.90.60.60.60.70.60.60.60.60.60.50.60.70.50.50.50.50.30.4
Bone: maximum force0.00.10.40.1-0.10.30.20.20.20.20.20.20.20.20.10.20.20.00.10.10.00.4-0.6
Bone: maximum moment0.00.00.30.20.00.20.10.10.10.10.10.10.10.1-0.00.10.1-0.00.10.1-0.00.2-0.6
Mean time between licks in bursts1.12.84.4-2.1-2.0-1.7-1.6-1.6-1.7-1.6-1.6-1.6-1.6-1.6-1.6-1.7-1.6-1.8-1.8-1.8-1.7-1.3-1.4
Mean num. licks in bursts0.50.71.1-0.6-0.6-0.9-0.9-0.9-0.8-0.9-0.9-0.9-0.9-0.8-0.9-0.9-0.9-0.8-0.8-0.8-0.8-1.1-0.6
Cd content in liver1.61.72.1-1.4-1.3-1.4-1.3-1.3-1.3-1.3-1.2-1.2-1.4-1.3-1.3-1.3-1.4-1.4-1.4-1.4-1.4-1.4-0.8
Co content in liver0.10.10.2-0.5-0.4-0.3-0.2-0.2-0.3-0.2-0.3-0.3-0.2-0.3-0.2-0.3-0.3-0.3-0.3-0.3-0.2-0.20.1
Cu content in liver0.20.20.5-0.2-0.2-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.4-0.4-0.4-0.4-0.7-0.1
Fe content in liver0.00.10.10.30.20.20.30.30.20.30.30.30.10.30.30.20.10.0-0.0-0.00.10.1-0.2
K content in liver0.10.10.5-0.7-0.7-0.1-0.2-0.2-0.3-0.2-0.3-0.3-0.1-0.2-0.2-0.2-0.2-0.2-0.1-0.1-0.10.4-0.7
Mg content in liver0.30.31.1-0.4-0.6-0.3-0.5-0.5-0.5-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.4-0.5-0.5-0.5-0.4-0.3-1.0
Mn content in liver0.40.41.50.20.40.50.60.60.60.60.60.60.70.60.50.60.70.70.70.70.70.81.2
Na content in liver0.60.61.11.10.90.90.70.70.80.70.70.70.80.70.70.80.80.80.80.80.80.80.2
Rb content in liver4.55.27.3-2.0-2.1-2.2-2.2-2.2-2.3-2.2-2.3-2.2-2.3-2.2-2.2-2.3-2.4-2.4-2.4-2.4-2.4-2.3-2.7
Se content in liver1.01.22.21.11.20.91.11.11.11.11.11.11.01.11.21.01.01.01.01.01.00.71.5
Sr content in liver1.00.91.11.11.10.90.90.91.00.90.90.90.90.90.90.90.90.90.90.90.90.81.0
Zn content in liver1.71.92.5-1.0-1.1-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.4-1.6-1.4
Bone: minimum diameter0.30.50.70.80.70.70.80.80.70.80.80.80.70.80.60.70.70.40.50.50.50.60.2
Time in familiar zone, hab. session 10.60.51.31.11.10.70.70.80.80.80.80.80.70.80.80.70.70.60.50.50.70.30.6
Time in novel zone, hab. session 10.80.81.6-1.2-1.1-1.0-0.9-0.9-0.9-0.9-0.9-1.0-0.9-0.9-0.9-0.8-0.9-0.8-0.6-0.6-0.9-0.7-0.2
Total zone transitions, hab. session 14.36.06.52.52.52.52.52.52.52.52.52.52.52.42.52.52.52.42.32.32.32.42.2
Total locomotion distance, hab. session 14.56.47.92.82.82.52.52.52.62.52.52.52.52.52.52.52.52.52.52.52.42.22.4
Locomotion velocity, hab. session 14.05.67.32.72.62.42.42.42.42.42.42.42.32.32.42.42.32.42.32.32.32.12.1
Time in familiar zone, hab. session 22.22.33.7-1.6-1.7-1.4-1.5-1.5-1.5-1.5-1.4-1.4-1.4-1.5-1.5-1.5-1.5-1.6-1.6-1.6-1.6-1.2-1.9
Time in novel zone, hab. session 20.40.51.50.70.80.50.60.60.70.60.60.60.60.70.60.60.60.70.70.70.60.41.2
Total zone transitions, hab. session 22.93.75.21.51.52.02.02.01.92.02.02.02.01.91.91.91.92.01.91.91.92.31.6
Total locomotion distance, hab. session 23.34.34.91.91.92.12.12.12.12.12.12.12.12.12.12.12.12.12.12.12.02.22.0
Locomotion velocity, hab. session 22.63.44.01.61.71.91.91.91.81.91.91.91.91.81.91.91.91.91.91.91.82.01.8
Novel to familiar place preference ratio0.10.10.10.30.30.30.20.20.30.20.20.20.40.20.30.30.40.30.30.30.40.30.2
Novelty place preference0.00.00.00.10.10.1-0.0-0.10.0-0.1-0.1-0.10.1-0.1-0.00.00.10.10.10.10.10.0-0.1
Time in novel zone, NPP test0.00.00.00.10.10.0-0.1-0.10.0-0.1-0.1-0.10.1-0.1-0.0-0.00.10.00.00.00.1-0.00.0
Total zone transitions, NPP test6.69.510.53.13.03.23.13.13.13.13.13.13.13.13.03.13.13.13.13.13.13.22.4
Total locomotion distance, NPP test6.08.39.12.82.83.02.92.92.92.92.92.82.92.82.92.92.93.02.92.92.93.02.4
Locomotion velocity, NPP test6.49.010.43.02.93.23.03.03.03.03.03.03.12.93.03.03.13.13.13.13.03.22.2
Intraocular pressure0.50.71.0-1.0-0.8-1.0-0.8-0.8-0.8-0.7-0.8-0.8-0.8-0.8-0.7-0.8-0.8-0.8-1.0-1.0-0.9-1.00.1
Delta distance traveled before/after self-admin2.93.14.41.51.61.71.71.71.81.61.71.81.61.71.61.81.71.82.02.01.81.82.1
Delta ambulatory time before/after self-admin3.34.05.61.81.91.91.92.02.11.92.02.01.92.01.82.11.92.02.22.22.02.02.4
Parametrial fat weight4.510.611.53.03.03.33.33.43.33.33.43.43.33.33.43.33.23.33.23.23.23.32.9
Pavlov. Cond. lever latency2.43.05.3-2.3-2.1-1.8-1.7-1.7-1.8-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.7-1.6-1.4-1.2
Pavlov. Cond. magazine entry latency0.40.51.61.31.20.60.70.70.70.70.60.70.60.70.70.60.60.70.60.60.60.10.7
Pavlov. Cond. change in total contacts2.02.13.21.81.81.31.51.51.51.51.51.51.41.41.51.41.41.41.41.41.11.01.6
Pavlov. Cond. index score2.43.05.52.42.21.71.71.71.81.71.71.71.71.71.71.71.71.71.71.71.61.21.4
Pavlov. Cond. latency score1.51.94.32.11.91.41.41.41.41.41.31.31.31.31.31.41.41.31.41.41.20.91.0
Pavlov. Cond. lever contacts2.83.45.42.32.21.91.81.81.91.81.81.81.81.81.81.81.81.81.81.81.71.51.4
Pavlov. Cond. magazine entry number2.12.74.6-2.2-2.1-1.6-1.6-1.6-1.7-1.6-1.6-1.6-1.6-1.6-1.7-1.6-1.6-1.6-1.5-1.5-1.5-1.1-1.5
Pavlov. Cond. intertrial magazine entries0.91.11.4-1.2-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-1.0-1.1-1.0-1.0-1.1-1.0-0.9
Pavlov. Cond. lever-magazine prob. diff.2.22.75.02.22.11.61.61.61.71.61.61.61.61.61.61.61.61.61.61.61.51.11.4
Pavlov. Cond. response bias3.54.46.62.62.52.12.12.12.12.12.12.12.12.12.12.12.12.12.02.02.01.61.9
Pavlov. Cond. lever latency2.83.84.9-1.8-1.7-2.1-2.0-2.0-2.0-2.0-2.0-2.0-2.0-2.0-1.9-2.0-1.9-1.9-2.0-2.0-1.9-2.2-1.4
Pavlov. Cond. magazine entry latency2.53.13.71.71.61.91.81.81.81.81.91.91.81.71.81.81.71.71.71.71.61.91.0
Pavlov. Cond. change in total contacts2.43.95.31.81.72.22.02.02.02.02.02.02.02.11.92.01.92.02.02.02.02.31.3
Pavlov. Cond. index score4.66.17.32.42.32.72.52.62.52.52.62.62.52.52.42.52.42.52.52.52.42.71.7
Pavlov. Cond. latency score5.06.67.82.52.42.82.62.72.62.62.72.72.62.62.62.62.52.62.62.62.52.81.8
Pavlov. Cond. lever contacts3.04.25.51.91.82.32.12.22.12.12.22.22.12.12.02.12.02.02.02.02.02.31.3
Pavlov. Cond. magazine entry number0.81.01.4-1.0-0.9-1.2-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-1.0-0.9-0.9-0.9-0.9-0.9-1.2-0.1
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.00.0-0.2-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.1-0.0-0.00.00.00.0-0.20.4
Pavlov. Cond. lever-magazine prob. diff.4.86.47.72.42.32.72.62.62.52.62.62.62.52.62.52.62.52.52.52.52.52.81.7
Pavlov. Cond. response bias1.21.62.61.11.01.51.31.31.21.31.31.31.31.31.21.31.21.21.31.31.21.60.4
Time in closed arm before self-admin0.00.00.2-0.5-0.4-0.1-0.1-0.2-0.2-0.1-0.2-0.2-0.1-0.20.0-0.2-0.2-0.1-0.3-0.3-0.10.1-0.3
Time in closed arm after self-admin0.10.10.7-0.5-0.50.30.40.30.20.40.40.30.40.20.50.30.30.20.20.20.30.9-0.1
Time in open arm before self-admin2.22.43.51.91.81.51.51.61.61.51.61.61.51.61.51.61.51.41.61.61.41.21.3
Time in open arm after self-admin0.40.51.31.11.10.50.50.60.70.50.70.70.60.80.40.70.70.70.60.60.50.11.0
Bone: periosteal estimation0.00.10.20.50.40.30.30.30.30.30.30.30.30.30.20.30.30.10.20.20.10.1-0.0
Bone: periosteal perimeter0.81.52.11.51.31.41.31.31.21.31.31.31.21.31.11.21.31.11.11.11.11.20.4
Bone: post-yield work0.00.10.2-0.2-0.10.30.30.30.20.30.30.30.30.20.20.20.30.00.20.20.00.5-0.0
Progressive ratio test 1 active lever presses1.01.21.40.80.91.11.21.21.11.21.21.11.11.21.11.11.11.00.91.11.11.21.0
Progressive ratio test 1 breakpoint0.91.11.30.80.81.01.11.11.01.11.11.11.11.11.11.01.11.00.91.01.01.10.9
Progressive ratio test 1 inactive lever presses0.81.21.51.11.11.01.21.11.11.21.11.11.11.11.21.01.10.91.00.91.00.91.1
Progressive ratio test 2 active lever presses2.73.14.01.91.91.81.91.91.82.01.91.91.81.91.91.71.81.51.51.41.61.61.6
Progressive ratio test 2 breakpoint3.13.54.32.02.01.92.02.01.92.12.02.01.92.01.91.81.91.61.61.51.71.61.7
Progressive ratio test 2 inactive lever presses0.71.21.81.11.11.01.31.21.01.31.11.21.21.21.31.01.10.90.80.71.00.91.0
Incentive Sensitization - Responses1.41.92.41.51.51.41.51.51.41.61.41.51.51.51.41.31.51.21.21.01.21.11.3
Incentive Sensitization - Breakpoint1.51.92.41.51.51.41.51.51.41.61.51.51.51.51.41.31.51.21.21.01.21.21.3
Sum of active levers in priming session hrs 5-60.10.10.70.50.5-0.3-0.2-0.2-0.1-0.1-0.3-0.3-0.3-0.2-0.2-0.2-0.3-0.1-0.1-0.1-0.0-0.80.6
Progressive ratio0.60.91.4-0.7-0.8-0.8-1.0-1.0-0.9-1.0-1.0-1.0-0.9-1.0-1.0-0.9-0.9-0.8-0.9-0.9-0.8-0.8-1.2
Food seeking constrained by brief footshock0.10.10.30.20.20.40.20.40.30.20.40.40.30.40.30.40.30.30.30.30.30.50.1
Seeking ratio, punishment vs. effort0.40.50.90.60.60.60.80.80.70.80.80.80.60.80.80.80.60.70.70.70.70.70.9
Retroperitoneal fat weight2.912.315.23.93.93.53.53.63.63.53.53.63.43.63.63.53.53.43.33.43.53.03.3
Reaction time number correct0.10.20.70.00.1-0.5-0.4-0.3-0.3-0.3-0.4-0.4-0.6-0.4-0.3-0.4-0.5-0.5-0.5-0.5-0.5-0.90.0
Reaction time mean minus median0.10.20.6-0.3-0.4-0.3-0.5-0.5-0.4-0.5-0.4-0.4-0.4-0.5-0.5-0.4-0.4-0.2-0.2-0.2-0.2-0.3-0.8
Reaction time mean minus median AUC0.20.50.8-0.9-0.9-0.6-0.8-0.8-0.8-0.8-0.7-0.7-0.7-0.7-0.8-0.7-0.7-0.5-0.5-0.5-0.5-0.4-0.9
Reaction time num false alarms0.71.01.1-1.0-1.0-1.0-1.0-0.9-1.0-0.9-0.9-0.9-1.0-0.9-1.0-1.0-1.1-0.9-1.0-1.0-1.0-0.9-1.0
Reaction time num false alarms AUC0.50.70.9-0.8-0.8-0.8-0.8-0.8-0.9-0.8-0.8-0.8-0.9-0.8-0.9-0.9-0.9-0.8-0.9-0.9-0.8-0.8-0.9
Reaction time trials correct on left0.10.20.70.00.1-0.5-0.4-0.3-0.3-0.3-0.4-0.4-0.6-0.4-0.3-0.4-0.5-0.5-0.5-0.5-0.5-0.90.0
Reaction time trials on left0.10.10.60.10.1-0.5-0.3-0.3-0.3-0.3-0.3-0.3-0.5-0.4-0.3-0.3-0.5-0.4-0.4-0.4-0.4-0.80.0
Reaction time mean0.10.20.8-0.8-0.9-0.2-0.3-0.3-0.4-0.3-0.3-0.3-0.2-0.3-0.2-0.3-0.2-0.2-0.2-0.1-0.20.3-0.8
Reaction time mean AUC0.10.10.8-0.9-0.9-0.1-0.2-0.2-0.3-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.2-0.1-0.1-0.1-0.10.4-0.7
Median of all reaction times0.10.10.6-0.8-0.8-0.0-0.1-0.1-0.3-0.1-0.1-0.2-0.0-0.1-0.0-0.1-0.1-0.1-0.1-0.1-0.10.5-0.6
Reaction time omissions0.30.40.60.60.50.70.60.60.60.60.60.60.60.70.60.60.60.70.80.70.70.80.2
Reaction time false alarm rate0.60.81.2-1.1-1.1-0.8-0.9-0.9-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.9-0.9-0.8-0.8-0.8-0.8-0.6-1.1
Reaction time premature initiation rate1.11.51.71.31.31.21.21.21.21.21.21.21.21.21.21.21.31.31.31.21.31.21.2
Reaction time premature initiations0.71.32.01.41.41.01.11.11.21.11.11.11.01.11.11.11.11.11.11.01.10.81.3
Std. dev. reaction times0.10.21.1-0.7-0.8-0.2-0.4-0.4-0.5-0.4-0.4-0.4-0.3-0.4-0.4-0.4-0.3-0.2-0.2-0.2-0.20.1-1.0
Reaction time trials completed0.10.10.60.10.1-0.5-0.3-0.3-0.3-0.3-0.3-0.3-0.5-0.4-0.3-0.3-0.5-0.4-0.4-0.4-0.4-0.80.0
Reaction time trials AUC0.00.10.40.30.3-0.3-0.1-0.1-0.1-0.1-0.2-0.2-0.3-0.2-0.1-0.2-0.3-0.3-0.3-0.3-0.2-0.60.2
Run reversals in cocaine runway, females0.90.91.51.21.11.00.91.01.01.01.01.01.01.01.01.01.00.80.90.90.70.70.6
Run reversals in cocaine runway, males0.10.10.30.30.40.20.30.30.20.30.40.20.30.30.40.20.30.10.10.10.10.10.6
Latency to leave start box in cocaine runway1.61.82.31.41.41.31.41.51.41.51.51.51.21.41.31.41.21.31.21.21.31.21.2
Latency to leave start box in cocaine runway, F0.30.30.60.50.50.60.60.80.60.70.80.80.40.60.50.60.40.50.50.50.60.60.4
Latency to leave start box in cocaine runway, M4.64.35.12.32.32.02.12.12.12.12.02.12.12.12.12.12.12.02.02.02.01.72.1
Std. dev. time between licks in bursts1.31.82.8-1.3-1.3-1.3-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.3-1.2-1.7-1.6-1.6-1.6-1.4-1.0
Total sessions with >9 infusions0.00.00.1-0.1-0.1-0.3-0.1-0.1-0.2-0.1-0.1-0.1-0.2-0.1-0.2-0.2-0.2-0.3-0.4-0.3-0.3-0.40.0
Short access day 1 total inactive lever presses0.20.30.40.50.60.50.60.60.50.60.50.50.60.50.60.50.60.40.30.30.50.40.5
Short access day 10 total inactive lever presses0.10.20.40.30.30.40.50.40.30.50.30.30.50.30.60.30.40.40.40.40.40.40.4
Short access day 1 total infusions0.20.30.5-0.4-0.4-0.6-0.4-0.4-0.5-0.4-0.4-0.4-0.5-0.4-0.5-0.5-0.5-0.7-0.7-0.7-0.6-0.7-0.3
Short access day 10 total infusions0.00.00.1-0.2-0.2-0.10.00.0-0.20.1-0.0-0.0-0.1-0.00.1-0.1-0.1-0.3-0.3-0.3-0.2-0.1-0.2
Short access total infusions0.81.01.4-1.0-1.0-1.0-0.8-0.9-1.0-0.8-0.9-0.9-1.0-0.9-0.9-1.0-1.0-1.2-1.2-1.2-1.1-1.0-0.8
Short access day 1 locomotion0.10.10.2-0.3-0.3-0.3-0.2-0.2-0.3-0.2-0.2-0.2-0.3-0.2-0.4-0.3-0.2-0.5-0.4-0.3-0.4-0.3-0.2
Short access day 10 total locomotion0.40.81.6-1.3-1.2-0.9-0.9-0.9-0.9-0.9-0.8-0.9-0.9-0.9-0.8-0.8-0.9-0.8-0.9-0.8-1.0-0.6-1.0
Short access total locomotion0.50.60.9-0.8-0.8-0.9-0.8-0.7-0.8-0.8-0.7-0.7-0.9-0.7-0.8-0.8-0.9-0.9-0.9-0.8-0.9-0.9-0.7
One hour access (0.3 mA shock)0.10.10.40.20.1-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.5-0.4-0.2-0.4-0.4-0.4-0.4-0.6-0.3
Compulsive drug intake0.10.20.3-0.2-0.2-0.4-0.5-0.5-0.4-0.5-0.5-0.5-0.4-0.5-0.4-0.5-0.3-0.3-0.3-0.3-0.3-0.6-0.2
One hour access (shock baseline)0.30.50.70.80.70.70.80.80.70.80.80.70.70.80.60.70.70.60.60.60.60.60.4
Social response proportion1.11.32.6-1.1-1.2-0.9-1.1-1.0-1.1-1.0-0.9-0.9-1.1-1.0-1.2-1.1-1.1-1.3-1.2-1.2-1.2-0.9-1.6
Social responses2.22.85.7-1.5-1.7-1.5-1.6-1.6-1.7-1.6-1.6-1.6-1.6-1.6-1.7-1.7-1.6-1.8-1.7-1.7-1.7-1.4-2.4
Social time1.11.52.8-0.4-0.6-1.2-1.2-1.2-1.2-1.2-1.2-1.2-1.3-1.2-1.3-1.2-1.2-1.3-1.3-1.3-1.2-1.7-1.3
Soleus weight0.41.31.91.41.21.21.11.11.11.11.11.11.21.11.21.11.21.11.11.11.11.00.6
Bone: stiffness0.00.00.1-0.1-0.10.10.00.10.00.00.10.10.10.1-0.1-0.00.1-0.2-0.2-0.2-0.20.1-0.4
Tibialis anterior weight0.20.81.20.80.80.90.90.90.90.90.90.90.90.91.10.90.80.80.90.90.90.90.8
Time to tail flick, vehicle, before self-admin0.40.40.9-0.4-0.5-0.6-0.4-0.5-0.7-0.3-0.6-0.6-0.6-0.7-0.2-0.6-0.7-0.4-0.8-0.8-0.6-0.6-1.0
Time to tail flick, vehicle, after self-admin2.73.65.4-2.2-2.3-1.7-1.9-1.9-2.0-1.9-1.9-1.9-1.8-1.9-1.8-1.9-1.9-1.7-1.6-1.6-1.8-1.3-2.3
Time to tail flick, test, before self-admin3.53.65.2-1.3-1.4-2.0-2.0-1.9-1.8-1.9-1.9-1.8-2.1-1.8-2.0-1.9-2.1-2.1-1.9-1.9-2.0-2.3-1.5
Time to tail flick, test, after self-admin1.61.62.2-1.2-1.2-1.2-1.4-1.4-1.2-1.4-1.4-1.3-1.4-1.3-1.5-1.2-1.4-1.1-1.0-1.0-1.1-1.2-1.2
Delta time to tail flick, vehicle, before/after SA1.11.01.4-1.1-1.1-0.9-1.1-1.1-1.0-1.2-1.1-1.1-1.0-0.9-1.2-1.0-1.0-1.0-0.7-0.7-0.9-0.7-1.1
Delta time to tail flick, test, before/after SA0.50.51.70.10.00.90.60.60.60.60.60.60.80.70.60.70.71.00.80.80.81.30.1
Tibia length3.08.310.63.23.22.92.82.82.92.82.72.72.92.82.82.92.92.93.03.03.02.52.8
Ambulatory time before self-admin0.10.10.3-0.0-0.0-0.3-0.3-0.3-0.3-0.3-0.3-0.3-0.2-0.3-0.2-0.3-0.1-0.4-0.4-0.4-0.3-0.5-0.3
Ambulatory time after self-admin2.42.83.91.81.91.51.61.71.71.51.71.71.71.61.51.71.71.61.71.71.61.42.0
Bone: tissue strength0.10.10.2-0.1-0.2-0.2-0.3-0.4-0.3-0.3-0.3-0.4-0.2-0.3-0.4-0.3-0.2-0.2-0.1-0.1-0.2-0.3-0.4
Total heroin consumption0.30.30.70.50.60.50.60.70.60.60.80.80.60.80.60.50.60.00.40.40.20.40.6
Bone: trabecular number0.71.12.6-1.3-1.4-0.9-1.0-1.0-1.1-1.0-1.0-1.0-1.0-0.9-0.9-1.0-1.0-1.1-1.0-1.0-1.1-0.6-1.6
Bone: trabecular spacing0.40.61.21.11.10.60.70.70.70.70.60.60.70.60.70.70.80.80.70.70.80.31.1
Bone: trabecular thickness1.11.42.3-1.5-1.5-1.1-1.1-1.1-1.2-1.1-1.1-1.1-1.1-1.0-1.2-1.2-1.1-1.2-1.2-1.2-1.2-0.8-1.4
Bone: trabecular tissue density0.10.21.00.20.3-0.5-0.3-0.3-0.2-0.3-0.4-0.4-0.4-0.3-0.2-0.3-0.3-0.3-0.3-0.3-0.4-1.00.7
Water consumed over 24 hours2.83.75.02.22.22.01.91.92.01.91.81.91.92.01.81.91.92.02.02.02.01.71.7
Number of responses in last shaping day0.00.00.10.20.20.10.20.20.10.20.10.20.10.20.10.10.10.00.10.10.10.00.2