Hub : Genes

Rpl3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Rpl3 0.06 0.03 1.8e-05 0.03 0.04 0.04 0.04 3.5e-04 8.5e-05 8.6e-05 1.6e-04
2 NAcc gene expression Rpl3 0.02 0.01 8.3e-04 0.03 0.01 0.01 0.02 6.4e-05 1.2e-02 1.1e-02 8.2e-04
3 BLA gene expression Rpl3 0.1 0.06 4.5e-04 0.06 0.05 0.06 0.05 2.4e-04 1.7e-03 5.7e-04 7.4e-04
4 PL gene expression Rpl3 0.11 0.06 3.5e-10 0.1 0.1 0.09 0.09 4.7e-11 1.7e-10 1.2e-09 2.5e-10
5 Adipose gene expression Rpl3 0.09 0.05 4.5e-10 0.07 0.09 0.08 0.08 1.5e-08 9.4e-10 2.2e-09 8.5e-09
6 IC gene expression Rpl3 0.1 0.06 1.7e-03 0.06 0.07 0.08 0.08 1.1e-03 5.1e-04 3.9e-04 2.1e-04
7 Adipose mRNA stability Rpl3 0.07 0.05 8.0e-04 0.01 0.02 0.02 0.01 3.2e-02 5.5e-03 4.7e-03 9.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.10.40.40.10.40.30.10.60.1
Area under the delay curve3.54.05.82.12.41.81.8-2.31.5-2.0
BMI with tail1.03.44.9-1.6-1.8-1.8-1.92.2-1.42.2
BMI without tail0.30.92.8-0.9-0.9-0.4-0.41.70.11.3
Body weight1.35.88.0-2.8-2.5-2.3-2.42.5-2.12.1
Weight adjusted by age0.10.20.7-0.8-0.3-0.1-0.20.0-0.5-0.4
Bone surface0.30.50.80.50.70.70.6-0.90.5-0.8
Bone volume0.00.00.10.20.10.20.1-0.20.1-0.1
Breakpoint value in progressive ratio session0.00.00.10.3-0.1-0.1-0.00.00.20.2
Number of licking bursts1.01.72.31.01.21.41.4-1.31.0-1.5
Context. condit. distance diff. score8.19.811.9-3.4-3.2-3.2-3.23.0-3.12.6
Locomotion velocity, session 11.41.53.70.61.21.10.9-1.60.5-1.9
Locomotion distance, session 15.77.19.52.43.12.62.4-3.11.9-3.1
Locomotion velocity, session 20.00.00.10.1-0.2-0.3-0.2-0.2-0.20.1
Locomotion distance, session 26.79.311.93.23.43.02.9-3.12.7-2.9
Locomotion velocity, session 32.02.34.5-2.1-1.2-1.6-1.51.0-1.90.7
Locomotion distance, session 30.30.30.9-0.40.20.30.3-0.7-0.4-0.9
Stereotopy head waving bouts, day 30.00.00.0-0.1-0.1-0.2-0.20.0-0.10.0
Stereotopy head waving duration, day 31.11.31.8-1.1-1.1-1.3-1.31.0-1.01.1
Locomotion velocity, session 71.11.21.9-1.0-1.4-1.1-1.20.4-1.40.8
Locomotion distance, session 70.20.30.90.30.10.40.3-0.90.1-0.8
Stereotopy head waving bouts, day 75.05.66.8-2.6-2.6-2.5-2.42.0-2.52.0
Stereotopy head waving duration, day 76.07.28.3-2.5-2.9-2.8-2.72.6-2.42.8
Locomotion velocity, session 80.60.71.2-1.1-1.0-0.9-0.90.4-1.00.3
Locomotion distance, session 80.81.11.7-1.1-0.7-1.1-1.31.1-1.11.0
Degree of sensitization distance0.60.61.4-0.1-1.0-0.7-0.70.9-0.11.2
Degree of sensitization stereotypy4.34.75.7-2.3-2.4-2.2-2.21.9-2.21.9
Conditioned locomotion0.30.40.6-0.7-0.8-0.5-0.60.5-0.60.4
Cocaine response after cond. corrected0.10.10.20.20.30.30.1-0.40.1-0.4
Cocaine response after cond. not corrected0.00.00.00.20.0-0.0-0.2-0.00.00.1
Cocaine response before conditioning0.20.30.8-0.2-0.4-0.5-0.30.6-0.20.9
Saline control response0.71.01.5-1.1-1.2-0.9-0.81.1-0.71.0
Bone: connectivity density0.00.00.10.0-0.00.30.2-0.00.3-0.1
Bone: cortical apparent density0.10.10.6-0.8-0.3-0.1-0.10.2-0.4-0.1
Bone: cortical area0.10.10.20.0-0.3-0.4-0.40.0-0.30.3
Bone: cortical porosity1.21.33.2-0.4-1.2-1.2-1.11.1-0.61.8
Bone: cortical porosity1.41.52.9-0.6-1.4-1.4-1.31.1-0.91.7
Bone: cortical thickness0.10.20.50.70.50.30.3-0.50.3-0.3
Bone: cortical thickness1.61.92.61.51.61.21.2-1.60.9-1.5
Bone: cortical tissue density0.10.10.6-0.8-0.3-0.1-0.10.1-0.4-0.2
Condit. Reinf. active minus inactive responses0.30.30.50.20.70.50.6-0.60.3-0.7
Condit. Reinf. active-inactive response ratio0.30.30.6-0.8-0.5-0.5-0.60.3-0.80.1
Condit. Reinf. active responses0.40.50.90.51.00.81.0-0.30.9-0.4
Condit. Reinf. inactive responses0.50.61.40.70.90.81.00.01.20.0
Incentive salience index mean0.40.50.70.50.80.80.8-0.60.7-0.7
Condit. Reinf. lever presses0.20.30.40.50.60.60.6-0.30.7-0.3
Condit. Reinf. active minus inactive responses1.72.23.71.21.51.31.4-1.90.9-1.8
Condit. Reinf. active-inactive response ratio0.70.81.50.71.00.70.7-1.20.5-1.1
Condit. Reinf. active responses0.60.92.50.70.80.50.7-1.60.1-1.4
Condit. Reinf. inactive responses0.20.31.00.10.0-0.10.0-1.0-0.5-0.7
Condit. Reinf. lever presses0.50.71.01.00.80.90.8-0.70.9-0.7
Condit. Reinf. lever reinforcers received0.60.82.00.70.80.50.7-1.40.3-1.2
Conditioned reinforcement - actives1.42.44.91.41.51.41.2-2.20.7-2.1
Conditioned reinforcement - inactives4.66.87.52.72.62.72.4-2.52.5-2.7
Conditioned locomotion0.81.01.81.31.10.90.8-1.10.9-0.9
Patch foraging indifference point 0 sec0.20.41.10.50.60.60.70.31.10.1
Patch foraging indifference point AUC3.95.69.51.82.32.32.4-2.91.5-3.1
Delay disc. indifference point, 0s delay0.30.30.80.1-0.4-0.5-0.60.6-0.10.9
Delay disc. indifference point, 16s delay4.44.85.92.22.42.12.1-2.41.7-2.2
Delay disc. indifference point, 2s delay1.82.04.02.01.41.11.1-1.90.9-1.2
Delay disc. indifference point, 24s delay3.43.87.21.12.21.71.9-2.41.0-2.7
Delay disc. indifference point, 4s delay1.81.93.31.51.81.21.1-1.51.1-1.3
Delay disc. indifference point, 8s delay3.64.36.61.92.62.12.0-2.01.7-2.1
Indifference point function ln k3.66.37.2-2.4-2.5-2.6-2.62.7-2.12.7
Indifference point function log k3.66.37.2-2.4-2.5-2.6-2.62.7-2.12.7
Patch foraging total patch changes 0 sec0.30.61.70.70.80.80.90.21.30.0
Patch foraging total patch changes 12 sec0.40.50.80.80.70.50.7-0.90.5-0.7
Patch foraging total patch changes 18 sec2.23.34.11.81.72.02.0-1.62.0-1.6
Patch foraging total patch changes 24 sec0.71.31.61.21.01.31.2-1.11.1-1.1
Patch foraging total patch changes 6 sec2.94.45.72.01.92.32.4-1.82.3-2.0
Patch foraging time to switch 0 sec0.30.62.00.2-0.6-0.8-1.00.7-0.31.4
Patch foraging water rate 0 sec0.20.50.90.10.70.91.0-0.10.9-0.7
Patch foraging water rate 12 sec0.10.20.6-0.3-0.2-0.00.20.80.30.7
Patch foraging water rate 18 sec0.40.71.70.20.41.01.3-0.31.2-0.6
Patch foraging water rate 24 sec0.91.32.3-1.4-1.1-0.9-0.81.5-0.61.3
Patch foraging water rate 6 sec0.10.10.4-0.6-0.20.00.10.50.10.2
Seeking ratio, delayed vs. immediate footshock0.20.20.40.40.50.40.5-0.00.7-0.1
Distance traveled before self-admin0.81.12.81.71.10.90.9-0.71.1-0.3
Distance traveled after self-admin1.61.93.11.41.31.51.7-0.91.8-1.0
Extensor digitorum longus weight0.20.71.61.10.81.00.70.21.30.0
Bone: elastic displacement0.10.10.3-0.5-0.1-0.2-0.30.3-0.30.2
Bone: elastic work0.30.40.8-0.5-0.4-0.7-0.90.6-0.60.8
Bone: endosteal estimation0.10.20.4-0.3-0.6-0.6-0.60.1-0.40.4
Bone: endosteal perimeter0.81.72.3-1.1-1.5-1.5-1.40.9-1.31.2
Epididymis fat weight3.411.713.9-3.4-3.7-3.7-3.52.8-3.63.1
Delta time in closed arm before/after self-admin0.40.30.90.50.50.40.3-0.90.0-0.9
Delta time in open arm before/after self-admin0.20.20.40.40.50.50.7-0.20.6-0.2
Diff in mean of infusions in LGA sessions0.20.20.70.00.10.30.4-0.70.1-0.8
Delay discount exponential model param3.74.26.1-2.1-2.5-1.9-1.92.3-1.52.1
Extinction: sum of active levers before priming0.20.20.80.60.0-0.1-0.1-0.9-0.3-0.4
Active lever presses in extinction session 60.10.10.1-0.0-0.4-0.3-0.40.1-0.20.2
Bone: final force0.00.00.10.30.0-0.2-0.3-0.3-0.10.0
Bone: final moment0.00.00.20.30.0-0.1-0.2-0.4-0.0-0.1
Food consumed during 24 hour testing period0.00.00.10.0-0.3-0.3-0.2-0.1-0.20.1
Glucose0.20.41.2-0.2-0.3-0.6-0.60.9-0.11.1
Heart weight0.81.31.8-1.2-1.2-1.1-1.21.3-0.81.1
Delay discount hyperbolic model param3.43.85.6-2.1-2.4-1.7-1.72.2-1.41.9
Intermittent access intake day 1-15 change0.00.10.2-0.00.10.20.20.40.40.0
Intermittent access intake escalation0.00.10.10.00.20.30.20.20.4-0.2
Intermittent access intake escalation 20.10.10.30.00.10.40.30.40.50.0
Intermitt. access day 1 inactive lever presses0.00.10.30.50.40.20.10.10.50.3
Intermitt. access day 15 inactive lever presses0.91.82.61.31.41.61.2-1.01.5-1.3
Intermitt. access escalation Index0.00.00.10.2-0.10.20.30.00.30.1
Intermittent access day 1 total infusions1.62.64.41.91.71.31.1-2.11.0-1.8
Intermittent access day 15 total infusions1.72.53.31.61.81.51.3-1.61.2-1.8
Intermittent access terminal intake (last 3 days)1.82.33.11.61.71.41.3-1.71.2-1.8
Intermittent access total infusions3.64.25.82.42.21.81.6-2.41.5-2.3
Intermittent access day 1 locomotion1.72.23.71.91.61.51.2-1.31.5-1.2
Intermittent access day 15 total locomotion0.40.71.21.10.80.70.6-0.90.8-0.9
Intermittent access total locomotion1.21.41.81.31.01.21.0-1.21.2-1.3
Intermittent access standard deviation0.20.41.41.20.80.40.3-0.20.8-0.2
Left kidney weight4.420.427.0-4.6-4.7-5.0-5.13.0-5.23.4
Right kidney weight5.424.731.8-5.1-5.2-5.4-5.63.8-5.44.0
Cocaine induced anxiety0.60.91.3-0.9-1.2-1.1-1.10.5-1.10.5
Post-drug Anxiety0.60.71.5-1.2-1.0-0.7-0.70.7-0.90.3
Baseline Anxiety0.70.81.20.51.01.11.1-0.70.8-1.0
Tail length0.10.30.7-0.8-0.20.40.30.80.40.1
Length with tail0.62.86.2-2.5-1.7-1.4-1.51.5-1.60.9
Length without tail1.13.54.8-2.2-2.0-2.0-2.01.4-2.01.3
Times rat made contact with spout0.60.71.70.40.80.90.9-0.80.6-1.3
Lifetime Intake3.13.86.32.42.01.51.4-2.51.3-2.2
Liver weight, left1.52.43.9-1.8-1.7-1.7-1.61.0-2.00.8
Liver weight, right6.511.315.1-3.9-3.4-3.5-3.13.3-3.42.9
Locomotor activity0.91.42.1-1.5-1.4-1.2-1.11.2-1.10.9
Locomotor testing distance0.00.00.1-0.1-0.10.20.20.20.2-0.1
Locomotor testing rearing0.71.42.3-1.1-1.5-1.3-1.20.9-1.21.0
Locomotion in novel chamber0.10.10.2-0.10.20.40.30.50.30.2
Locomotion in novel chamber post-restriction0.00.10.30.50.30.10.3-0.20.20.0
Fecal boli incidents, locomotor time 11.82.63.31.61.21.81.8-1.61.7-1.7
Change in fecal boli incidents, locomotor task1.21.23.0-1.7-1.0-0.8-1.00.1-1.6-0.3
Time >=10cm from walls, locomotor time 10.00.00.1-0.30.1-0.2-0.20.1-0.20.1
Bouts of movement, locomotor time 10.60.71.5-0.9-1.0-0.9-1.00.1-1.20.1
Total resting periods, locomotor time 10.20.20.4-0.4-0.3-0.4-0.6-0.2-0.7-0.2
Rest time, locomotor task time 10.10.10.2-0.0-0.5-0.1-0.4-0.1-0.3-0.1
Distance moved, locomotor task time 10.71.11.6-1.1-0.5-1.1-1.01.3-0.91.3
Vertical activity count, locomotor time 10.10.20.7-0.7-0.3-0.20.00.80.10.5
Time >=10cm from walls, locomotor time 20.00.00.1-0.10.20.20.20.10.3-0.1
Bouts of movement, locomotor time 20.50.81.5-0.2-1.2-1.1-1.10.3-1.00.9
Total resting periods, locomotor time 20.20.30.60.2-0.8-0.6-0.6-0.1-0.60.5
Rest time, locomotor task time 20.60.81.40.70.90.80.8-1.10.5-1.2
Distance moved, locomotor task time 21.31.52.1-1.2-1.0-1.2-1.21.4-1.11.4
Vertical activity count, locomotor time 20.30.51.0-0.7-1.0-0.6-0.40.8-0.30.6
Light reinforcement 10.10.10.30.50.30.30.4-0.30.6-0.2
Light reinforcement 22.03.14.0-1.3-1.7-2.0-2.01.6-1.71.9
Bone: marrow area0.10.20.4-0.3-0.6-0.6-0.60.1-0.40.4
Bone: maximum diameter0.61.21.9-0.9-1.2-1.3-1.40.6-1.20.9
Bone: maximum force0.10.20.50.60.20.10.0-0.70.1-0.5
Bone: maximum moment0.10.20.50.50.10.10.0-0.70.1-0.5
Mean time between licks in bursts0.10.30.70.80.70.60.50.00.80.0
Mean num. licks in bursts0.60.91.2-1.1-0.9-1.0-1.10.8-1.10.6
Cd content in liver0.30.30.8-0.80.2-0.10.2-0.4-0.5-0.9
Co content in liver1.82.12.91.31.51.71.5-1.01.5-1.4
Cu content in liver3.84.56.22.32.42.42.2-1.42.5-1.4
Fe content in liver0.70.91.6-0.9-1.1-0.8-0.71.3-0.21.2
K content in liver0.10.10.20.40.20.50.4-0.30.4-0.2
Mg content in liver0.30.30.50.70.30.60.7-0.40.7-0.1
Mn content in liver0.20.20.6-0.4-0.5-0.5-0.2-0.1-0.80.2
Na content in liver0.30.40.90.60.40.80.60.01.0-0.2
Rb content in liver0.80.91.41.10.70.80.9-1.20.8-0.9
Se content in liver0.20.20.5-0.7-0.1-0.2-0.30.6-0.40.3
Sr content in liver1.10.91.51.11.21.20.9-0.41.1-0.5
Zn content in liver0.20.20.6-0.00.80.50.1-0.30.0-0.5
Bone: minimum diameter0.10.10.20.0-0.5-0.4-0.4-0.1-0.30.3
Time in familiar zone, hab. session 10.80.71.80.50.60.70.7-1.30.3-1.4
Time in novel zone, hab. session 11.51.53.3-1.0-1.0-1.0-0.91.8-0.61.7
Total zone transitions, hab. session 11.42.03.20.61.81.61.5-1.40.9-1.7
Total locomotion distance, hab. session 10.30.51.0-0.20.80.60.6-0.80.0-1.0
Locomotion velocity, hab. session 10.71.01.90.31.41.10.9-1.10.4-1.3
Time in familiar zone, hab. session 20.30.30.5-0.7-0.4-0.6-0.70.5-0.70.4
Time in novel zone, hab. session 20.40.40.70.70.40.70.8-0.50.7-0.4
Total zone transitions, hab. session 23.54.55.81.82.22.22.1-2.21.8-2.4
Total locomotion distance, hab. session 22.33.03.71.71.91.81.7-1.61.7-1.6
Locomotion velocity, hab. session 23.14.15.02.02.22.22.0-1.92.0-1.9
Novel to familiar place preference ratio1.31.42.8-1.7-1.3-1.0-0.91.4-1.00.8
Novelty place preference2.02.14.4-2.1-1.6-1.2-1.11.6-1.30.9
Time in novel zone, NPP test2.32.45.1-2.3-1.7-1.3-1.21.7-1.50.9
Total zone transitions, NPP test3.24.76.81.42.42.32.3-2.31.6-2.6
Total locomotion distance, NPP test2.02.73.81.21.91.71.7-1.81.2-1.9
Locomotion velocity, NPP test2.02.83.61.41.91.81.7-1.81.3-1.8
Intraocular pressure0.60.91.7-0.9-1.1-1.0-1.00.1-1.30.5
Delta distance traveled before/after self-admin0.20.20.8-0.9-0.5-0.00.20.0-0.1-0.4
Delta ambulatory time before/after self-admin0.20.20.7-0.6-0.10.20.4-0.30.1-0.8
Parametrial fat weight0.71.62.8-1.7-1.7-0.9-0.81.5-0.91.2
Pavlov. Cond. lever latency0.00.00.1-0.3-0.3-0.1-0.10.1-0.3-0.1
Pavlov. Cond. magazine entry latency0.91.11.81.31.10.90.9-1.20.9-0.9
Pavlov. Cond. change in total contacts2.52.74.02.01.51.51.7-1.71.6-1.4
Pavlov. Cond. index score0.50.60.91.00.80.60.6-0.90.7-0.7
Pavlov. Cond. latency score0.20.30.50.70.70.40.4-0.50.6-0.4
Pavlov. Cond. lever contacts0.40.50.90.90.80.60.6-0.50.8-0.3
Pavlov. Cond. magazine entry number1.21.52.2-1.4-1.2-1.1-1.11.5-1.01.3
Pavlov. Cond. intertrial magazine entries1.41.72.80.91.21.61.7-0.91.5-1.2
Pavlov. Cond. lever-magazine prob. diff.0.40.60.90.90.80.60.6-0.90.6-0.7
Pavlov. Cond. response bias0.81.01.61.31.10.80.8-1.20.8-0.8
Pavlov. Cond. lever latency0.20.30.9-0.7-0.3-0.5-0.5-0.2-0.9-0.3
Pavlov. Cond. magazine entry latency3.03.75.12.12.02.02.1-1.42.3-1.3
Pavlov. Cond. change in total contacts0.50.81.91.10.80.91.0-0.51.4-0.3
Pavlov. Cond. index score1.21.62.71.41.21.31.4-0.71.7-0.7
Pavlov. Cond. latency score1.62.13.41.61.41.51.6-0.91.9-0.9
Pavlov. Cond. lever contacts0.30.31.10.70.20.60.60.21.00.3
Pavlov. Cond. magazine entry number1.01.32.0-1.2-1.2-1.2-1.30.7-1.40.8
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.1-0.4-0.3-0.3-0.3-0.5-0.2
Pavlov. Cond. lever-magazine prob. diff.1.01.42.61.31.11.21.3-0.51.6-0.5
Pavlov. Cond. response bias0.70.92.01.20.71.01.1-0.41.4-0.2
Time in closed arm before self-admin1.51.94.91.51.11.41.60.12.20.1
Time in closed arm after self-admin0.00.00.10.20.00.20.3-0.00.4-0.1
Time in open arm before self-admin0.20.30.6-0.8-0.2-0.3-0.60.1-0.8-0.2
Time in open arm after self-admin0.00.00.1-0.30.1-0.0-0.00.2-0.10.1
Bone: periosteal estimation0.20.30.6-0.3-0.6-0.8-0.80.1-0.60.5
Bone: periosteal perimeter1.22.13.1-1.3-1.5-1.8-1.61.0-1.51.3
Bone: post-yield work1.72.53.81.41.51.51.6-1.91.2-2.0
Progressive ratio test 1 active lever presses2.53.14.82.01.91.51.4-2.21.2-2.0
Progressive ratio test 1 breakpoint2.63.24.91.91.91.51.4-2.21.2-2.1
Progressive ratio test 1 inactive lever presses2.43.56.92.61.91.81.6-1.71.9-1.2
Progressive ratio test 2 active lever presses2.83.26.31.81.61.41.4-2.51.0-2.3
Progressive ratio test 2 breakpoint2.93.36.61.91.71.41.3-2.61.0-2.3
Progressive ratio test 2 inactive lever presses2.23.64.62.11.91.91.7-2.11.6-2.0
Incentive Sensitization - Responses0.40.51.30.60.40.60.6-1.20.3-1.0
Incentive Sensitization - Breakpoint0.30.41.20.50.30.50.5-1.10.2-0.9
Sum of active levers in priming session hrs 5-60.00.00.1-0.00.0-0.00.00.30.10.3
Progressive ratio0.20.40.70.60.60.60.6-0.20.9-0.4
Food seeking constrained by brief footshock0.10.10.20.10.1-0.3-0.2-0.5-0.4-0.2
Seeking ratio, punishment vs. effort0.10.10.4-0.1-0.3-0.5-0.3-0.3-0.60.1
Retroperitoneal fat weight4.217.923.9-4.2-4.9-4.6-4.33.2-4.53.6
Reaction time number correct0.20.30.8-0.6-0.6-0.6-0.4-0.0-0.90.2
Reaction time mean minus median0.00.00.20.0-0.1-0.1-0.10.40.20.3
Reaction time mean minus median AUC0.41.01.3-0.8-1.0-1.1-1.11.2-0.81.1
Reaction time num false alarms0.10.20.7-0.5-0.3-0.2-0.20.8-0.00.5
Reaction time num false alarms AUC0.10.10.4-0.5-0.4-0.2-0.10.6-0.10.2
Reaction time trials correct on left0.20.30.8-0.6-0.6-0.6-0.4-0.0-0.90.2
Reaction time trials on left0.10.30.7-0.6-0.6-0.5-0.3-0.1-0.80.1
Reaction time mean0.10.10.5-0.1-0.1-0.2-0.20.70.10.6
Reaction time mean AUC0.10.10.3-0.1-0.1-0.2-0.20.50.00.4
Median of all reaction times0.10.10.4-0.00.0-0.2-0.10.60.10.6
Reaction time omissions0.20.40.60.80.60.50.4-0.70.4-0.5
Reaction time false alarm rate0.10.10.6-0.2-0.2-0.0-0.10.80.20.4
Reaction time premature initiation rate0.30.51.01.00.50.60.5-0.51.0-0.3
Reaction time premature initiations0.00.10.20.50.10.20.2-0.40.3-0.1
Std. dev. reaction times0.20.30.8-0.6-0.5-0.5-0.50.9-0.30.6
Reaction time trials completed0.10.30.7-0.6-0.6-0.5-0.3-0.1-0.80.1
Reaction time trials AUC0.20.40.9-0.7-0.8-0.7-0.50.1-1.00.3
Run reversals in cocaine runway, females0.10.10.4-0.6-0.5-0.2-0.00.4-0.30.1
Run reversals in cocaine runway, males0.50.51.8-0.50.50.2-0.0-0.9-0.8-1.3
Latency to leave start box in cocaine runway1.61.82.4-1.0-1.2-1.5-1.51.1-1.41.5
Latency to leave start box in cocaine runway, F0.10.10.30.0-0.0-0.5-0.40.1-0.40.5
Latency to leave start box in cocaine runway, M3.73.44.0-1.7-2.0-2.0-1.91.7-1.81.9
Std. dev. time between licks in bursts0.91.22.11.11.01.31.2-0.81.4-0.8
Total sessions with >9 infusions0.30.41.31.00.30.0-0.1-1.1-0.1-0.7
Short access day 1 total inactive lever presses3.14.05.12.12.12.21.9-1.62.3-1.7
Short access day 10 total inactive lever presses0.00.10.2-0.5-0.4-0.1-0.20.4-0.10.0
Short access day 1 total infusions0.50.71.41.20.70.70.6-0.90.8-0.8
Short access day 10 total infusions0.30.31.11.00.50.10.0-0.90.1-0.5
Short access total infusions1.01.32.91.70.90.60.6-1.70.6-1.2
Short access day 1 locomotion0.30.30.80.90.60.60.3-0.10.8-0.1
Short access day 10 total locomotion0.61.12.71.50.91.20.9-0.01.60.1
Short access total locomotion0.30.31.21.10.50.40.2-0.10.80.1
One hour access (0.3 mA shock)3.54.06.32.52.31.91.5-2.21.6-1.9
Compulsive drug intake1.51.84.10.51.21.21.3-1.70.6-2.0
One hour access (shock baseline)0.30.52.01.40.80.40.2-0.40.7-0.0
Social response proportion0.50.51.80.20.1-0.4-0.51.20.31.3
Social responses0.70.91.01.00.71.01.0-0.91.0-1.0
Social time2.33.14.62.21.91.81.8-1.32.0-1.0
Soleus weight0.82.34.21.11.21.71.5-1.71.1-2.0
Bone: stiffness0.00.00.10.3-0.2-0.2-0.10.10.20.3
Tibialis anterior weight1.55.07.02.62.32.52.3-1.62.5-1.6
Time to tail flick, vehicle, before self-admin0.20.20.30.20.30.40.5-0.30.5-0.5
Time to tail flick, vehicle, after self-admin0.30.40.7-0.10.60.80.80.10.8-0.5
Time to tail flick, test, before self-admin0.30.30.7-0.3-0.5-0.6-0.7-0.1-0.80.2
Time to tail flick, test, after self-admin0.00.00.10.10.10.30.3-0.00.3-0.1
Delta time to tail flick, vehicle, before/after SA0.20.20.40.40.70.50.4-0.00.5-0.0
Delta time to tail flick, test, before/after SA0.70.71.70.50.71.01.20.01.3-0.4
Tibia length0.10.30.7-0.5-0.0-0.3-0.4-0.7-0.8-0.6
Ambulatory time before self-admin0.60.92.01.41.11.00.9-0.71.0-0.4
Ambulatory time after self-admin2.12.53.81.21.61.81.9-1.11.9-1.4
Bone: tissue strength0.30.40.6-0.8-0.7-0.6-0.60.2-0.70.2
Total heroin consumption0.50.61.60.80.70.50.5-1.30.2-1.1
Bone: trabecular number0.20.30.7-0.7-0.8-0.5-0.50.4-0.60.4
Bone: trabecular spacing0.30.41.10.50.40.40.4-1.00.2-1.0
Bone: trabecular thickness0.60.81.9-0.4-1.0-0.7-0.81.1-0.31.4
Bone: trabecular tissue density0.50.72.00.60.70.70.90.71.40.5
Water consumed over 24 hours0.60.81.60.50.81.01.1-0.70.8-1.2
Number of responses in last shaping day2.52.77.22.71.51.51.3-1.31.9-0.4