Hub : Genes

Rnf8

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc isoform ratio XM_063279229.1 0.07 0.05 2.0e-07 0.04 0.04 0.04 0.04 4.8e-07 2.6e-07 1.3e-06 8.4e-07
2 NAcc alternative polyA XM_063279229.1 0.06 0.04 2.1e-06 0.04 0.04 0.03 0.03 2.4e-06 1.5e-06 9.8e-06 5.6e-06
3 NAcc alternative polyA XM_063279230.1 0.03 0.03 5.5e-04 0.01 0.02 0.02 0.02 1.7e-03 3.1e-04 9.9e-04 4.6e-04
4 pVTA alternative polyA XM_063279229.1 0.05 0.04 2.4e-03 0.03 0.02 0.03 0.03 1.2e-03 6.3e-03 2.1e-03 3.1e-03
5 OFC gene expression Rnf8 0.12 0.11 9.1e-03 0.09 0.07 0.1 0.1 3.9e-03 8.5e-03 2.1e-03 2.1e-03
6 Liver alternative TSS NM_001025727.1 0.04 0.04 7.1e-05 0.03 0.03 0.03 0.03 9.3e-05 1.2e-04 1.1e-04 1.6e-04
7 Liver alternative TSS XM_063279229.1 0.04 0.04 6.8e-05 0.03 0.03 0.03 0.03 1.0e-04 1.4e-04 1.6e-04 2.1e-04
8 BLA mRNA stability Rnf8 0.05 0.04 4.8e-03 0.04 0.03 0.04 0.03 2.6e-03 1.0e-02 3.7e-03 7.1e-03
9 pVTA isoform ratio XM_063279229.1 0.04 0.03 3.3e-03 0.03 0.02 0.03 0.03 1.1e-03 6.9e-03 1.9e-03 2.5e-03
10 Adipose mRNA stability Rnf8 0.05 0.04 1.1e-05 0.04 0.04 0.04 0.04 1.3e-05 1.8e-05 2.4e-05 2.6e-05
11 Liver gene expression Rnf8 0.92 0.04 0.0e+00 0.65 0.64 0.65 0.65 2.2e-96 6.1e-94 9.2e-95 7.3e-95
12 NAcc gene expression Rnf8 0.04 0.03 1.3e-05 0.03 0.03 0.02 0.03 4.7e-05 3.1e-05 1.4e-04 7.7e-05
13 pVTA mRNA stability Rnf8 0.04 0.03 8.4e-04 0.03 0.03 0.03 0.02 1.3e-03 1.2e-03 2.5e-03 6.9e-03
14 Brain alternative polyA XM_063279229.1 0.06 0.05 1.6e-05 0.06 0.04 0.06 0.06 3.6e-06 2.5e-04 6.3e-06 7.0e-06
15 Brain isoform ratio XM_063279229.1 0.05 0.04 3.9e-06 0.06 0.05 0.06 0.06 1.8e-06 8.4e-06 2.6e-06 2.2e-06
16 Adipose gene expression Rnf8 0.48 0.15 0.0e+00 0.53 0.53 0.54 0.54 6.3e-69 2.8e-69 5.8e-70 3.8e-70
17 BLA gene expression Rnf8 0.07 0.05 1.4e-04 0.07 0.08 0.08 0.08 9.2e-05 5.0e-05 6.1e-05 7.7e-05
18 Brain gene expression Rnf8 0.09 0.06 1.7e-09 0.09 0.08 0.09 0.09 9.6e-09 3.2e-08 1.9e-08 1.6e-08
19 LHb isoform ratio XM_063279229.1 0.28 0.28 1.1e-03 0.12 0.08 0.09 0.1 1.1e-03 5.7e-03 3.8e-03 2.7e-03
20 Liver alternative polyA XM_063279230.1 0.02 0.02 1.7e-03 0.01 0 0 0 4.7e-02 1.2e-01 1.5e-01 1.6e-01
21 Liver alternative polyA XM_063279229.1 0.03 0.03 3.1e-04 0.02 0.02 0.02 0.02 1.7e-03 2.4e-03 4.2e-03 4.7e-03
22 Liver isoform ratio XM_063279229.1 0.02 0.02 4.6e-03 0.01 0 0 0 3.9e-02 9.0e-02 2.2e-01 1.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.81.41.9-1.3-1.31.3-1.0-0.91.4-1.41.3-0.9-1.3-1.3-1.21.1-1.3-1.3-1.2-1.1-0.8-0.71.2-1.2-1.2
Area under the delay curve1.01.22.71.00.9-1.01.31.6-1.01.0-0.81.40.90.91.0-1.11.01.01.11.11.21.1-1.01.01.0
BMI with tail2.89.711.63.33.3-3.33.03.1-3.43.4-3.42.83.23.23.2-3.23.13.13.23.12.72.6-2.92.92.9
BMI without tail2.37.07.82.82.7-2.82.82.3-2.82.8-2.82.42.72.72.7-2.72.72.72.62.72.52.5-2.52.52.5
Body weight5.724.726.75.05.0-5.15.24.7-5.25.2-5.15.15.05.04.9-5.05.05.05.15.15.05.1-4.54.54.5
Weight adjusted by age2.43.65.62.22.2-2.10.91.9-2.02.0-2.20.82.02.02.2-1.92.42.41.61.70.70.7-2.12.12.1
Bone surface0.00.00.20.00.1-0.1-0.00.40.0-0.0-0.1-0.1-0.1-0.10.1-0.1-0.0-0.0-0.00.1-0.00.0-0.10.10.1
Bone volume0.00.00.2-0.1-0.0-0.00.10.50.1-0.10.10.1-0.2-0.20.1-0.10.00.0-0.00.10.30.3-0.10.10.1
Breakpoint value in progressive ratio session0.10.10.4-0.3-0.30.3-0.2-0.40.3-0.30.4-0.3-0.2-0.2-0.40.4-0.2-0.2-0.4-0.3-0.2-0.20.7-0.7-0.7
Number of licking bursts0.30.50.7-0.7-0.70.7-0.8-0.80.7-0.70.7-0.9-0.7-0.7-0.60.7-0.8-0.8-0.8-0.7-0.6-0.70.7-0.7-0.7
Context. condit. distance diff. score0.20.30.7-0.3-0.40.4-0.4-0.50.5-0.50.4-0.4-0.2-0.2-0.50.5-0.5-0.5-0.5-0.5-0.8-0.80.6-0.6-0.6
Locomotion velocity, session 11.41.53.1-1.3-1.31.3-0.9-1.50.9-0.91.0-0.8-0.9-0.9-1.41.3-1.4-1.4-0.9-1.2-0.8-0.81.8-1.8-1.8
Locomotion distance, session 13.44.34.9-2.1-2.12.1-2.0-1.92.1-2.12.2-2.1-2.0-2.0-2.12.1-2.0-2.0-2.2-2.1-2.1-2.12.1-2.1-2.1
Locomotion velocity, session 20.30.30.4-0.5-0.50.5-0.6-0.40.6-0.60.6-0.5-0.4-0.4-0.50.5-0.5-0.5-0.6-0.6-0.5-0.60.6-0.6-0.6
Locomotion distance, session 20.71.01.4-1.0-1.01.0-1.0-0.71.0-1.01.1-1.1-0.8-0.8-1.01.0-0.8-0.8-1.1-1.0-1.0-1.11.2-1.2-1.2
Locomotion velocity, session 30.10.10.5-0.1-0.10.10.6-0.3-0.10.1-0.10.60.20.2-0.1-0.0-0.2-0.20.20.20.60.70.4-0.4-0.4
Locomotion distance, session 30.60.61.2-0.8-0.90.8-0.3-0.90.8-0.80.8-0.3-0.7-0.7-0.90.8-1.1-1.1-0.7-0.7-0.4-0.40.9-0.9-0.9
Stereotopy head waving bouts, day 31.71.92.61.41.4-1.41.61.1-1.41.4-1.41.61.61.61.3-1.41.41.41.41.51.51.5-1.11.11.1
Stereotopy head waving duration, day 30.40.50.80.80.8-0.80.50.8-0.70.7-0.70.40.90.90.7-0.70.80.80.60.60.20.2-0.60.60.6
Locomotion velocity, session 70.20.20.6-0.5-0.50.5-0.2-0.10.7-0.70.7-0.1-0.7-0.7-0.30.3-0.3-0.3-0.5-0.3-0.1-0.00.2-0.2-0.2
Locomotion distance, session 71.01.22.4-1.2-1.21.2-0.9-0.61.4-1.41.4-0.9-1.6-1.6-1.01.0-0.9-0.9-1.3-1.0-0.8-0.90.9-0.9-0.9
Stereotopy head waving bouts, day 70.50.61.50.60.6-0.61.10.4-0.60.6-0.61.10.90.90.6-0.70.50.50.80.81.11.2-0.50.50.5
Stereotopy head waving duration, day 70.60.71.50.70.7-0.81.10.6-0.70.7-0.81.21.01.00.8-0.90.60.60.91.01.11.2-0.70.70.7
Locomotion velocity, session 80.00.00.3-0.1-0.20.10.1-0.20.1-0.10.10.00.10.1-0.20.2-0.0-0.0-0.1-0.1-0.1-0.20.5-0.5-0.5
Locomotion distance, session 80.71.01.7-0.9-0.90.9-1.0-0.71.1-1.11.1-1.1-0.8-0.8-0.91.0-0.7-0.7-1.1-1.0-1.3-1.31.1-1.1-1.1
Degree of sensitization distance0.20.20.60.40.4-0.4-0.10.7-0.20.2-0.2-0.00.10.10.5-0.40.70.70.10.30.0-0.1-0.70.70.7
Degree of sensitization stereotypy0.20.20.5-0.6-0.50.5-0.1-0.70.6-0.60.5-0.1-0.2-0.2-0.50.4-0.6-0.6-0.4-0.3-0.00.10.5-0.5-0.5
Conditioned locomotion2.02.32.71.51.5-1.51.61.3-1.41.4-1.41.51.51.51.5-1.61.61.61.41.61.61.6-1.51.51.5
Cocaine response after cond. corrected1.92.23.21.81.7-1.71.11.5-1.71.7-1.71.11.81.81.6-1.51.61.61.41.40.70.6-1.51.51.5
Cocaine response after cond. not corrected1.51.82.61.61.5-1.51.11.2-1.61.6-1.61.11.61.61.4-1.31.31.31.41.20.80.7-1.31.31.3
Cocaine response before conditioning0.20.30.6-0.6-0.60.6-0.0-0.80.4-0.40.40.1-0.5-0.5-0.60.5-0.6-0.6-0.1-0.30.40.30.6-0.6-0.6
Saline control response0.30.40.80.50.5-0.50.70.3-0.60.6-0.60.90.60.60.5-0.50.60.60.70.60.90.9-0.40.40.4
Bone: connectivity density0.60.91.2-1.1-1.01.0-0.9-0.81.1-1.11.0-0.8-1.1-1.1-1.00.9-1.1-1.1-1.0-0.9-0.7-0.60.9-0.9-0.9
Bone: cortical apparent density0.10.20.3-0.5-0.50.5-0.2-0.40.5-0.50.5-0.1-0.4-0.4-0.40.4-0.5-0.5-0.4-0.3-0.2-0.20.3-0.3-0.3
Bone: cortical area0.50.71.21.00.9-0.90.71.1-0.90.9-0.90.70.80.80.9-0.90.80.80.90.80.70.6-0.80.80.8
Bone: cortical porosity0.00.00.00.10.1-0.1-0.0-0.1-0.20.2-0.2-0.10.20.20.1-0.10.10.10.10.10.10.0-0.10.10.1
Bone: cortical porosity0.00.00.10.20.2-0.2-0.00.1-0.20.2-0.2-0.00.30.30.2-0.20.20.20.20.20.10.0-0.20.20.2
Bone: cortical thickness0.10.20.3-0.4-0.40.4-0.6-0.40.4-0.40.4-0.5-0.4-0.4-0.40.4-0.4-0.4-0.3-0.5-0.3-0.40.5-0.5-0.5
Bone: cortical thickness0.00.00.1-0.1-0.10.10.1-0.3-0.00.00.00.2-0.1-0.1-0.10.1-0.1-0.10.00.00.30.30.3-0.3-0.3
Bone: cortical tissue density0.10.10.2-0.4-0.40.4-0.1-0.40.4-0.40.40.0-0.3-0.3-0.40.3-0.4-0.4-0.3-0.3-0.2-0.10.2-0.2-0.2
Condit. Reinf. active minus inactive responses1.21.31.9-1.2-1.21.2-1.0-1.11.1-1.11.1-1.0-1.2-1.2-1.21.2-1.0-1.0-1.0-1.2-1.0-1.01.4-1.4-1.4
Condit. Reinf. active-inactive response ratio0.10.10.2-0.2-0.30.3-0.1-0.20.1-0.10.1-0.2-0.3-0.3-0.30.3-0.2-0.2-0.1-0.3-0.3-0.30.4-0.4-0.4
Condit. Reinf. active responses0.60.81.4-1.0-1.01.0-0.6-1.00.8-0.80.8-0.7-0.9-0.9-1.00.9-0.8-0.8-0.7-0.8-0.4-0.41.2-1.2-1.2
Condit. Reinf. inactive responses0.91.01.5-1.2-1.21.1-0.8-1.21.1-1.11.1-0.8-1.0-1.0-1.11.1-1.0-1.0-0.9-0.9-0.3-0.31.2-1.2-1.2
Incentive salience index mean0.50.60.9-0.8-0.80.8-0.7-0.70.7-0.70.7-0.7-0.8-0.8-0.80.8-0.6-0.6-0.6-0.8-0.7-0.61.0-1.0-1.0
Condit. Reinf. lever presses0.00.00.0-0.1-0.10.1-0.10.10.0-0.00.0-0.2-0.1-0.1-0.10.10.20.20.1-0.1-0.1-0.10.1-0.1-0.1
Condit. Reinf. active minus inactive responses1.11.43.8-1.2-1.21.2-1.0-1.90.8-0.80.8-0.9-0.9-0.9-1.41.3-1.4-1.4-0.8-1.1-0.6-0.61.6-1.6-1.6
Condit. Reinf. active-inactive response ratio0.40.52.1-0.5-0.50.5-0.8-1.40.1-0.10.1-0.7-0.2-0.2-0.70.7-0.7-0.7-0.3-0.6-0.4-0.31.0-1.0-1.0
Condit. Reinf. active responses1.11.52.9-1.3-1.31.3-0.8-1.70.9-0.90.9-0.7-1.1-1.1-1.41.3-1.4-1.4-0.9-1.2-0.5-0.51.6-1.6-1.6
Condit. Reinf. inactive responses0.10.10.2-0.3-0.30.30.5-0.00.2-0.20.20.4-0.4-0.4-0.30.2-0.2-0.2-0.0-0.10.40.40.2-0.2-0.2
Condit. Reinf. lever presses4.35.97.3-2.5-2.62.6-2.0-2.52.3-2.32.2-2.0-2.5-2.5-2.72.6-2.5-2.5-2.3-2.5-2.1-2.22.7-2.7-2.7
Condit. Reinf. lever reinforcers received1.92.64.3-1.7-1.71.7-1.2-2.11.3-1.31.3-1.1-1.5-1.5-1.81.8-1.8-1.8-1.3-1.6-1.0-1.02.0-2.0-2.0
Conditioned reinforcement - actives0.20.30.80.40.4-0.40.9-0.0-0.70.7-0.70.90.70.70.3-0.40.30.30.60.50.80.70.1-0.1-0.1
Conditioned reinforcement - inactives0.00.10.1-0.3-0.30.2-0.2-0.30.1-0.10.1-0.2-0.2-0.2-0.30.3-0.2-0.2-0.1-0.2-0.0-0.00.4-0.4-0.4
Conditioned locomotion0.91.22.01.01.0-1.01.40.9-1.21.2-1.11.41.11.10.9-1.01.11.11.31.11.41.4-0.70.70.7
Patch foraging indifference point 0 sec0.30.60.90.70.7-0.70.81.0-0.60.6-0.60.80.60.60.8-0.80.80.80.80.81.00.8-0.90.90.9
Patch foraging indifference point AUC0.30.40.6-0.5-0.60.6-0.4-0.80.8-0.80.7-0.4-0.3-0.3-0.60.6-0.7-0.7-0.6-0.6-0.6-0.60.6-0.6-0.6
Delay disc. indifference point, 0s delay0.91.02.21.11.1-1.00.61.5-1.21.2-1.10.61.01.01.1-1.01.01.01.10.80.30.2-1.01.01.0
Delay disc. indifference point, 16s delay0.10.10.6-0.2-0.30.20.70.5-0.00.00.20.8-0.1-0.1-0.20.0-0.1-0.10.20.10.70.70.4-0.4-0.4
Delay disc. indifference point, 2s delay0.10.10.50.20.2-0.2-0.20.7-0.10.10.2-0.20.00.00.3-0.20.20.20.10.1-0.2-0.3-0.40.40.4
Delay disc. indifference point, 24s delay1.82.03.31.31.3-1.31.71.6-1.41.4-1.21.81.41.41.3-1.51.41.41.41.51.61.6-1.21.21.2
Delay disc. indifference point, 4s delay1.61.72.61.31.3-1.31.41.6-1.21.2-1.21.31.31.31.4-1.41.41.41.31.31.21.2-1.31.31.3
Delay disc. indifference point, 8s delay1.61.82.91.21.2-1.21.61.5-1.31.3-1.21.71.11.11.3-1.41.31.31.41.41.71.6-1.31.31.3
Indifference point function ln k0.00.00.2-0.1-0.10.1-0.40.1-0.10.1-0.0-0.4-0.4-0.4-0.00.10.00.0-0.1-0.2-0.3-0.2-0.20.20.2
Indifference point function log k0.00.00.2-0.1-0.10.1-0.40.1-0.10.1-0.0-0.4-0.4-0.4-0.00.10.00.0-0.1-0.2-0.3-0.2-0.20.20.2
Patch foraging total patch changes 0 sec0.40.71.10.70.8-0.80.81.0-0.70.7-0.60.80.60.60.9-0.80.80.80.80.80.90.8-1.11.11.1
Patch foraging total patch changes 12 sec0.00.00.00.10.1-0.00.1-0.20.1-0.10.10.10.20.20.00.0-0.2-0.20.10.00.1-0.10.1-0.1-0.1
Patch foraging total patch changes 18 sec0.30.51.30.60.6-0.61.10.8-0.40.4-0.41.10.60.60.6-0.70.40.40.60.81.10.8-0.70.70.7
Patch foraging total patch changes 24 sec0.10.20.5-0.3-0.30.4-0.4-0.40.5-0.50.5-0.4-0.4-0.4-0.30.3-0.7-0.7-0.4-0.4-0.5-0.60.0-0.0-0.0
Patch foraging total patch changes 6 sec0.10.10.30.40.4-0.40.60.4-0.10.1-0.10.40.40.40.4-0.40.30.30.40.40.40.3-0.30.30.3
Patch foraging time to switch 0 sec0.81.52.31.31.3-1.31.51.3-1.51.5-1.41.31.51.51.1-1.21.11.11.41.21.21.1-0.60.60.6
Patch foraging water rate 0 sec0.10.20.80.10.2-0.1-0.60.30.2-0.20.2-0.3-0.2-0.20.3-0.20.10.1-0.3-0.0-0.5-0.4-0.90.90.9
Patch foraging water rate 12 sec0.00.10.3-0.3-0.30.3-0.4-0.20.4-0.40.4-0.2-0.5-0.5-0.20.2-0.1-0.1-0.5-0.3-0.3-0.3-0.10.10.1
Patch foraging water rate 18 sec0.40.61.0-1.0-1.01.0-0.7-0.90.8-0.80.9-0.4-1.0-1.0-0.80.8-0.8-0.8-0.8-0.8-0.4-0.40.5-0.5-0.5
Patch foraging water rate 24 sec0.20.30.6-0.6-0.60.6-0.6-0.30.6-0.60.7-0.3-0.7-0.7-0.50.5-0.3-0.3-0.8-0.6-0.6-0.50.2-0.2-0.2
Patch foraging water rate 6 sec0.10.10.3-0.1-0.10.1-0.40.10.3-0.30.4-0.3-0.3-0.30.00.00.20.2-0.6-0.2-0.4-0.3-0.30.30.3
Seeking ratio, delayed vs. immediate footshock0.70.81.4-1.2-1.21.0-0.1-1.10.9-0.90.9-0.0-1.1-1.1-1.10.8-1.1-1.1-0.6-0.60.20.11.0-1.0-1.0
Distance traveled before self-admin0.70.91.20.90.9-0.90.90.7-0.90.9-1.01.00.90.91.0-1.00.90.91.01.01.01.1-1.01.01.0
Distance traveled after self-admin0.10.10.30.10.2-0.20.1-0.0-0.10.1-0.10.10.20.20.3-0.30.30.30.10.30.50.6-0.40.40.4
Extensor digitorum longus weight0.31.01.3-0.9-1.01.0-1.0-1.00.9-0.91.0-1.1-1.0-1.0-1.01.0-0.9-0.9-0.9-1.0-1.0-1.01.1-1.1-1.1
Bone: elastic displacement0.10.10.6-0.3-0.30.3-0.1-0.70.2-0.20.1-0.1-0.2-0.2-0.30.3-0.7-0.7-0.1-0.2-0.0-0.10.5-0.5-0.5
Bone: elastic work0.10.10.20.30.3-0.30.30.1-0.30.3-0.30.30.30.30.3-0.30.10.10.40.30.30.2-0.20.20.2
Bone: endosteal estimation3.37.28.72.72.7-2.72.93.0-2.82.8-2.82.72.62.62.7-2.72.62.62.82.72.42.4-2.72.72.7
Bone: endosteal perimeter2.34.95.82.42.3-2.32.12.4-2.42.4-2.42.02.22.22.3-2.22.12.12.32.21.81.8-2.22.22.2
Epididymis fat weight0.82.63.31.71.6-1.71.71.4-1.81.8-1.81.71.81.81.5-1.51.71.71.61.61.51.4-1.21.21.2
Delta time in closed arm before/after self-admin4.13.85.12.22.2-2.21.61.7-2.02.0-2.11.52.22.22.1-2.02.22.21.91.91.41.4-1.91.91.9
Delta time in open arm before/after self-admin1.31.21.8-1.3-1.31.3-0.8-0.81.2-1.21.2-0.8-1.3-1.3-1.31.2-1.1-1.1-1.0-1.1-0.7-0.71.2-1.2-1.2
Diff in mean of infusions in LGA sessions0.20.31.0-0.3-0.30.3-0.7-0.30.4-0.40.5-0.8-0.3-0.3-0.30.4-0.3-0.3-0.6-0.6-1.0-1.00.3-0.3-0.3
Delay discount exponential model param0.80.92.1-0.8-0.80.9-1.1-1.50.8-0.80.7-1.2-0.7-0.7-0.91.0-0.9-0.9-0.9-1.0-1.1-1.10.9-0.9-0.9
Extinction: sum of active levers before priming0.20.20.70.60.5-0.5-0.3-0.3-0.70.7-0.8-0.30.80.80.3-0.10.50.50.40.1-0.2-0.20.3-0.3-0.3
Active lever presses in extinction session 60.10.10.5-0.2-0.30.30.3-0.2-0.30.3-0.30.2-0.2-0.2-0.40.3-0.3-0.30.1-0.2-0.1-0.10.7-0.7-0.7
Bone: final force4.16.67.92.62.6-2.62.72.8-2.62.6-2.62.62.62.62.6-2.62.42.42.72.62.42.3-2.52.52.5
Bone: final moment3.55.77.32.42.4-2.42.62.7-2.42.4-2.42.52.42.42.4-2.42.22.22.52.42.22.1-2.32.32.3
Food consumed during 24 hour testing period0.81.12.41.11.1-1.10.90.8-1.51.5-1.50.81.11.11.0-1.01.01.01.31.00.90.8-0.80.80.8
Glucose0.20.40.70.80.8-0.70.00.6-0.80.8-0.80.00.60.60.7-0.60.50.50.50.4-0.1-0.1-0.70.70.7
Heart weight0.40.72.5-0.4-0.40.4-1.6-0.60.8-0.80.7-1.5-0.5-0.5-0.40.6-0.3-0.3-0.9-0.9-1.4-1.50.2-0.2-0.2
Delay discount hyperbolic model param0.60.61.7-0.7-0.70.7-0.9-1.30.7-0.70.5-1.0-0.6-0.6-0.80.8-0.8-0.8-0.8-0.8-0.9-0.80.8-0.8-0.8
Intermittent access intake day 1-15 change0.10.21.20.10.1-0.10.90.1-0.40.4-0.40.70.20.20.1-0.20.20.20.60.41.11.10.0-0.0-0.0
Intermittent access intake escalation0.10.21.4-0.1-0.10.01.00.0-0.30.3-0.20.90.00.0-0.1-0.10.00.00.50.41.21.20.1-0.1-0.1
Intermittent access intake escalation 20.20.30.5-0.7-0.70.60.1-0.60.4-0.40.40.0-0.5-0.5-0.70.5-0.6-0.6-0.2-0.30.50.50.7-0.7-0.7
Intermitt. access day 1 inactive lever presses0.10.51.8-0.3-0.30.4-1.3-0.60.4-0.40.4-1.3-0.4-0.4-0.30.6-0.5-0.5-0.5-0.7-1.3-1.30.4-0.4-0.4
Intermitt. access day 15 inactive lever presses0.10.10.9-0.00.0-0.10.6-0.2-0.10.1-0.00.50.20.20.1-0.2-0.0-0.00.30.30.90.9-0.00.00.0
Intermitt. access escalation Index0.40.50.8-0.7-0.70.7-0.8-0.50.8-0.80.8-0.7-0.8-0.8-0.70.7-0.7-0.7-0.9-0.8-0.8-0.80.5-0.5-0.5
Intermittent access day 1 total infusions0.61.01.8-1.0-1.01.0-0.8-1.01.0-1.00.9-0.7-0.9-0.9-1.01.0-1.3-1.3-1.0-0.9-0.8-0.81.1-1.1-1.1
Intermittent access day 15 total infusions0.20.40.8-0.7-0.70.70.2-0.60.5-0.50.50.1-0.6-0.6-0.70.5-0.9-0.9-0.4-0.40.20.20.7-0.7-0.7
Intermittent access terminal intake (last 3 days)0.00.10.2-0.2-0.20.20.2-0.30.1-0.1-0.00.2-0.1-0.1-0.20.1-0.5-0.50.0-0.00.30.30.3-0.3-0.3
Intermittent access total infusions0.40.51.3-0.8-0.80.8-0.2-0.70.7-0.70.7-0.2-0.7-0.7-0.80.7-1.1-1.1-0.7-0.6-0.2-0.20.8-0.8-0.8
Intermittent access day 1 locomotion0.10.10.20.20.2-0.20.40.3-0.20.2-0.20.50.20.20.2-0.2-0.0-0.00.30.30.50.4-0.20.20.2
Intermittent access day 15 total locomotion1.32.37.41.01.0-1.12.20.5-1.51.5-1.62.31.51.50.9-1.21.11.11.91.62.72.7-0.30.30.3
Intermittent access total locomotion0.30.41.90.00.0-0.11.1-0.1-0.40.4-0.41.20.40.4-0.0-0.2-0.1-0.10.60.51.41.30.3-0.3-0.3
Intermittent access standard deviation0.81.62.21.31.3-1.31.50.9-1.31.3-1.41.31.41.41.2-1.21.11.11.21.31.31.3-1.21.21.2
Left kidney weight2.913.316.23.63.6-3.63.93.5-3.63.6-3.74.03.63.63.6-3.73.43.43.63.84.03.9-3.43.43.4
Right kidney weight4.922.428.64.54.5-4.65.34.9-4.54.5-4.55.34.64.64.6-4.84.54.54.65.05.25.2-4.64.64.6
Cocaine induced anxiety0.10.20.4-0.6-0.50.5-0.5-0.40.5-0.50.6-0.6-0.7-0.7-0.40.4-0.4-0.4-0.4-0.4-0.1-0.10.2-0.2-0.2
Post-drug Anxiety0.50.50.8-0.9-0.80.8-0.6-0.70.8-0.80.8-0.7-0.9-0.9-0.70.7-0.7-0.7-0.6-0.7-0.3-0.30.7-0.7-0.7
Baseline Anxiety0.20.20.50.70.6-0.60.10.5-0.60.6-0.60.10.70.70.5-0.40.60.60.30.3-0.2-0.2-0.30.30.3
Tail length0.72.64.61.41.5-1.51.81.3-1.41.4-1.41.81.51.51.6-1.71.81.81.51.82.02.1-1.61.61.6
Length with tail1.77.211.22.52.5-2.62.82.4-2.62.6-2.63.02.62.62.6-2.72.92.92.72.93.23.3-2.32.32.3
Length without tail3.09.711.23.23.1-3.23.12.9-3.33.3-3.33.33.23.23.1-3.13.13.13.43.23.13.2-2.72.72.7
Times rat made contact with spout4.14.75.4-2.3-2.32.3-1.9-2.12.2-2.22.1-1.9-2.3-2.3-2.32.2-2.3-2.3-2.1-2.1-1.8-1.82.2-2.2-2.2
Lifetime Intake0.10.10.4-0.2-0.30.20.2-0.30.1-0.10.10.2-0.1-0.1-0.30.2-0.6-0.6-0.1-0.10.20.20.4-0.4-0.4
Liver weight, left2.03.34.51.91.9-1.92.02.1-1.61.6-1.61.81.81.81.9-2.01.81.81.51.91.61.6-1.91.91.9
Liver weight, right3.15.47.22.42.4-2.42.32.7-2.22.2-2.22.22.32.32.5-2.52.02.02.22.42.11.9-2.52.52.5
Locomotor activity0.10.20.70.30.3-0.30.60.70.0-0.00.10.30.10.10.4-0.40.80.80.10.40.20.2-0.40.40.4
Locomotor testing distance0.20.31.30.60.6-0.50.20.7-0.20.2-0.20.10.30.30.6-0.51.11.10.20.40.0-0.0-0.60.60.6
Locomotor testing rearing0.81.62.31.31.3-1.31.21.3-1.31.3-1.31.21.21.21.4-1.31.51.51.21.31.11.2-1.31.31.3
Locomotion in novel chamber0.10.20.7-0.2-0.20.2-0.80.40.3-0.30.3-0.4-0.3-0.3-0.10.1-0.4-0.4-0.4-0.3-0.7-0.7-0.30.30.3
Locomotion in novel chamber post-restriction1.62.63.51.61.6-1.61.61.6-1.61.6-1.61.91.71.71.7-1.71.41.41.61.71.61.6-1.61.61.6
Fecal boli incidents, locomotor time 10.10.10.40.20.2-0.20.30.70.0-0.00.00.3-0.2-0.20.2-0.2-0.0-0.0-0.10.20.10.1-0.50.50.5
Change in fecal boli incidents, locomotor task3.73.65.32.22.3-2.10.71.7-2.22.2-2.10.82.32.32.2-1.92.32.31.81.60.70.6-1.91.91.9
Time >=10cm from walls, locomotor time 13.03.24.42.12.1-2.01.21.7-1.71.7-1.81.22.12.12.0-1.92.12.11.51.71.11.1-1.81.81.8
Bouts of movement, locomotor time 10.50.50.9-0.7-0.80.7-0.4-0.80.7-0.70.4-0.5-1.0-1.0-0.80.8-0.9-0.9-0.7-0.7-0.4-0.40.8-0.8-0.8
Total resting periods, locomotor time 10.30.30.5-0.6-0.60.5-0.2-0.60.5-0.50.3-0.2-0.7-0.7-0.70.6-0.7-0.7-0.5-0.4-0.0-0.00.6-0.6-0.6
Rest time, locomotor task time 10.30.30.90.70.7-0.70.30.2-0.80.8-0.90.30.40.40.6-0.50.50.50.60.50.30.3-0.70.70.7
Distance moved, locomotor task time 10.10.10.30.20.2-0.20.20.3-0.40.4-0.30.30.60.60.1-0.20.30.30.40.20.20.30.2-0.2-0.2
Vertical activity count, locomotor time 10.20.50.80.60.6-0.60.80.9-0.80.8-0.70.80.80.80.7-0.70.80.80.80.70.70.7-0.40.40.4
Time >=10cm from walls, locomotor time 28.212.015.23.93.9-3.82.53.4-3.53.5-3.62.53.83.83.9-3.63.83.83.23.32.22.3-3.73.73.7
Bouts of movement, locomotor time 20.10.10.3-0.2-0.30.20.2-0.10.5-0.50.30.2-0.1-0.1-0.30.2-0.2-0.2-0.3-0.10.20.20.5-0.5-0.5
Total resting periods, locomotor time 20.10.20.5-0.4-0.40.4-0.2-0.40.7-0.70.6-0.2-0.4-0.4-0.50.4-0.3-0.3-0.6-0.4-0.2-0.20.6-0.6-0.6
Rest time, locomotor task time 20.00.10.20.30.3-0.3-0.00.0-0.40.4-0.30.00.10.10.3-0.20.20.20.40.20.10.1-0.20.20.2
Distance moved, locomotor task time 22.02.43.51.61.6-1.61.51.2-1.61.6-1.81.51.91.91.5-1.51.61.61.61.61.51.6-1.11.11.1
Vertical activity count, locomotor time 21.11.52.21.31.3-1.31.01.0-1.31.3-1.41.01.51.51.3-1.31.41.41.01.21.01.0-1.11.11.1
Light reinforcement 11.53.84.42.02.0-2.01.81.9-1.71.7-1.71.82.02.02.0-2.02.12.11.72.01.91.8-2.12.12.1
Light reinforcement 22.03.04.51.71.7-1.71.92.1-1.71.7-1.62.11.61.61.7-1.81.61.61.61.81.71.7-1.71.71.7
Bone: marrow area3.57.69.12.82.8-2.82.93.0-2.82.8-2.82.72.72.72.7-2.82.62.62.82.82.52.5-2.72.72.7
Bone: maximum diameter0.71.32.21.21.2-1.20.91.5-1.21.2-1.20.91.11.11.2-1.21.11.11.21.10.90.8-1.21.21.2
Bone: maximum force1.42.53.71.61.6-1.61.71.9-1.61.6-1.61.51.51.51.6-1.61.61.61.71.61.41.3-1.61.61.6
Bone: maximum moment1.11.93.21.41.4-1.41.51.8-1.41.4-1.41.41.31.31.4-1.41.31.31.51.41.21.1-1.41.41.4
Mean time between licks in bursts0.41.11.7-1.0-1.01.0-1.1-1.20.8-0.80.8-1.2-1.1-1.1-1.01.1-1.3-1.3-0.9-1.1-1.3-1.20.8-0.8-0.8
Mean num. licks in bursts0.30.50.7-0.8-0.90.8-0.5-0.50.8-0.80.8-0.5-0.8-0.8-0.90.8-0.7-0.7-0.7-0.7-0.6-0.60.8-0.8-0.8
Cd content in liver0.00.00.2-0.2-0.20.20.1-0.40.1-0.10.20.0-0.2-0.2-0.10.10.00.0-0.0-0.10.20.20.1-0.1-0.1
Co content in liver2.22.63.71.61.7-1.71.51.5-1.61.6-1.61.51.61.61.7-1.61.91.91.61.61.51.4-1.51.51.5
Cu content in liver2.52.94.4-1.7-1.61.7-2.0-1.31.9-1.91.9-2.0-1.8-1.8-1.51.6-1.3-1.3-2.0-1.8-2.1-2.11.3-1.3-1.3
Fe content in liver1.41.72.31.21.3-1.31.41.3-1.21.2-1.21.51.21.21.3-1.41.21.21.31.41.51.5-1.31.31.3
K content in liver0.60.61.2-0.7-0.60.7-1.0-0.60.8-0.80.7-0.9-0.7-0.7-0.60.7-0.5-0.5-0.9-0.8-1.0-1.10.5-0.5-0.5
Mg content in liver0.50.51.3-0.6-0.60.6-1.1-0.60.7-0.70.7-1.0-0.7-0.7-0.50.7-0.5-0.5-0.8-0.8-1.1-1.10.5-0.5-0.5
Mn content in liver0.10.10.20.30.3-0.2-0.00.2-0.20.2-0.2-0.10.30.30.3-0.20.20.20.10.2-0.1-0.2-0.40.40.4
Na content in liver0.30.30.5-0.6-0.60.6-0.7-0.70.5-0.50.5-0.6-0.6-0.6-0.60.6-0.6-0.6-0.6-0.5-0.3-0.30.6-0.6-0.6
Rb content in liver0.00.00.00.20.2-0.20.00.2-0.10.1-0.20.20.20.20.2-0.10.10.10.10.10.10.1-0.20.20.2
Se content in liver1.21.52.6-1.1-1.11.1-1.5-1.01.3-1.31.3-1.6-1.3-1.3-1.11.1-1.1-1.1-1.4-1.2-1.4-1.40.9-0.9-0.9
Sr content in liver0.00.00.1-0.1-0.10.1-0.2-0.30.0-0.00.1-0.1-0.1-0.1-0.10.1-0.0-0.0-0.1-0.1-0.0-0.00.2-0.2-0.2
Zn content in liver0.10.10.9-0.1-0.10.2-0.4-0.10.2-0.20.2-0.6-0.2-0.2-0.10.20.20.2-0.4-0.4-0.9-1.00.2-0.2-0.2
Bone: minimum diameter2.34.35.62.32.2-2.21.82.4-2.22.2-2.21.72.12.12.1-2.12.02.02.22.01.51.4-2.22.22.2
Time in familiar zone, hab. session 10.20.20.6-0.4-0.50.40.0-0.70.2-0.20.20.1-0.3-0.3-0.50.4-0.6-0.6-0.1-0.3-0.1-0.10.8-0.8-0.8
Time in novel zone, hab. session 10.80.81.60.90.9-0.90.61.3-0.70.7-0.70.50.80.81.0-0.91.11.10.60.80.50.5-1.21.21.2
Total zone transitions, hab. session 13.24.56.3-2.1-2.12.1-2.2-2.52.1-2.12.1-2.2-1.8-1.8-2.12.2-2.1-2.1-2.1-2.1-1.8-1.82.2-2.2-2.2
Total locomotion distance, hab. session 12.02.84.0-1.7-1.71.7-1.8-2.01.6-1.61.7-1.8-1.4-1.4-1.71.8-1.6-1.6-1.6-1.7-1.5-1.61.8-1.8-1.8
Locomotion velocity, hab. session 11.82.53.9-1.6-1.51.6-1.8-2.01.5-1.51.5-1.8-1.3-1.3-1.61.6-1.5-1.5-1.6-1.6-1.5-1.51.7-1.7-1.7
Time in familiar zone, hab. session 21.11.22.1-1.0-1.01.0-1.1-0.41.3-1.31.3-1.2-1.2-1.2-1.01.0-0.9-0.9-1.4-1.1-1.5-1.40.9-0.9-0.9
Time in novel zone, hab. session 21.11.12.40.90.8-0.91.40.4-1.21.2-1.21.41.11.10.8-0.90.70.71.21.11.61.5-0.60.60.6
Total zone transitions, hab. session 20.20.30.7-0.5-0.50.5-0.7-0.20.7-0.70.7-0.8-0.4-0.4-0.40.5-0.2-0.2-0.8-0.6-0.7-0.70.5-0.5-0.5
Total locomotion distance, hab. session 21.92.53.7-1.5-1.51.6-1.7-1.21.7-1.71.8-1.7-1.5-1.5-1.51.6-1.2-1.2-1.9-1.7-1.8-1.91.4-1.4-1.4
Locomotion velocity, hab. session 22.33.04.5-1.7-1.71.7-2.0-1.31.9-1.92.0-2.0-1.6-1.6-1.61.7-1.4-1.4-2.1-1.8-2.0-2.01.4-1.4-1.4
Novel to familiar place preference ratio0.60.71.20.90.9-0.90.50.5-1.11.1-1.00.60.90.90.8-0.80.90.90.90.70.50.5-0.60.60.6
Novelty place preference0.50.50.90.80.8-0.80.40.3-1.01.0-0.90.60.80.80.7-0.60.80.80.80.60.40.5-0.50.50.5
Time in novel zone, NPP test0.40.51.00.80.7-0.70.60.2-1.01.0-0.90.70.80.80.6-0.60.70.70.80.60.50.5-0.40.40.4
Total zone transitions, NPP test1.01.42.3-1.2-1.11.2-1.3-0.51.4-1.41.4-1.4-1.1-1.1-1.11.2-0.7-0.7-1.5-1.3-1.4-1.51.1-1.1-1.1
Total locomotion distance, NPP test0.81.01.9-0.9-0.91.0-1.2-0.41.2-1.21.2-1.3-0.9-0.9-0.91.0-0.5-0.5-1.4-1.1-1.3-1.40.8-0.8-0.8
Locomotion velocity, NPP test1.11.63.0-1.1-1.11.2-1.6-0.61.5-1.51.5-1.7-1.2-1.2-1.01.2-0.6-0.6-1.7-1.3-1.7-1.70.8-0.8-0.8
Intraocular pressure0.71.02.80.80.7-0.81.61.4-1.01.0-1.01.70.80.80.7-0.91.01.01.11.01.21.2-0.70.70.7
Delta distance traveled before/after self-admin0.30.30.9-0.5-0.50.5-0.8-0.70.5-0.50.6-0.9-0.5-0.5-0.50.6-0.4-0.4-0.8-0.6-0.7-0.70.4-0.4-0.4
Delta ambulatory time before/after self-admin0.30.40.9-0.6-0.60.6-0.9-0.80.7-0.70.7-0.9-0.6-0.6-0.60.6-0.6-0.6-0.9-0.6-0.6-0.50.4-0.4-0.4
Parametrial fat weight1.74.09.71.51.5-1.63.01.6-1.91.9-1.82.81.81.81.5-1.81.91.92.02.13.13.1-1.21.21.2
Pavlov. Cond. lever latency0.20.30.60.50.5-0.50.80.3-0.60.6-0.60.70.50.50.4-0.50.20.20.50.60.60.7-0.40.40.4
Pavlov. Cond. magazine entry latency0.30.30.5-0.6-0.60.6-0.4-0.10.6-0.60.6-0.6-0.6-0.6-0.60.6-0.4-0.4-0.6-0.6-0.6-0.70.6-0.6-0.6
Pavlov. Cond. change in total contacts0.40.40.80.50.5-0.50.80.4-0.80.8-0.80.80.60.60.4-0.50.60.60.90.60.90.9-0.20.20.2
Pavlov. Cond. index score0.00.00.2-0.0-0.10.1-0.10.50.1-0.10.1-0.3-0.1-0.1-0.00.10.30.3-0.1-0.2-0.3-0.40.0-0.0-0.0
Pavlov. Cond. latency score0.10.10.40.20.2-0.2-0.00.7-0.10.1-0.1-0.20.10.10.2-0.10.60.60.10.0-0.2-0.3-0.20.20.2
Pavlov. Cond. lever contacts0.00.00.1-0.1-0.10.1-0.30.10.1-0.10.1-0.4-0.1-0.1-0.00.10.30.3-0.1-0.2-0.2-0.30.1-0.1-0.1
Pavlov. Cond. magazine entry number0.40.61.00.70.7-0.70.70.2-0.70.7-0.70.90.80.80.7-0.80.50.50.70.80.91.0-0.70.70.7
Pavlov. Cond. intertrial magazine entries0.20.30.6-0.6-0.50.5-0.4-0.80.4-0.40.4-0.3-0.4-0.4-0.60.5-0.7-0.7-0.3-0.4-0.2-0.10.8-0.8-0.8
Pavlov. Cond. lever-magazine prob. diff.0.00.00.2-0.0-0.10.1-0.10.40.1-0.10.1-0.3-0.1-0.1-0.00.10.30.3-0.1-0.1-0.3-0.40.1-0.1-0.1
Pavlov. Cond. response bias0.70.81.1-0.9-1.00.9-0.9-0.60.9-0.90.9-1.0-0.9-0.9-1.01.0-0.8-0.8-0.8-1.0-0.9-0.91.1-1.1-1.1
Pavlov. Cond. lever latency2.53.44.72.12.1-2.11.31.8-1.81.8-1.81.22.22.22.1-2.01.81.81.81.81.21.4-2.02.02.0
Pavlov. Cond. magazine entry latency0.10.10.8-0.1-0.10.10.5-0.2-0.20.2-0.20.6-0.1-0.1-0.1-0.0-0.1-0.10.40.20.90.70.2-0.2-0.2
Pavlov. Cond. change in total contacts1.32.13.1-1.6-1.61.6-1.0-1.81.3-1.31.4-1.0-1.6-1.6-1.71.6-1.5-1.5-1.3-1.4-0.8-0.91.7-1.7-1.7
Pavlov. Cond. index score0.81.01.6-1.2-1.21.2-0.5-1.20.8-0.80.9-0.4-1.2-1.2-1.21.1-1.1-1.1-0.7-0.9-0.3-0.41.3-1.3-1.3
Pavlov. Cond. latency score0.60.71.2-1.0-1.01.0-0.4-1.10.7-0.70.7-0.3-1.0-1.0-1.00.9-0.9-0.9-0.6-0.8-0.2-0.31.1-1.1-1.1
Pavlov. Cond. lever contacts2.12.94.0-1.9-1.91.9-1.2-1.81.6-1.61.6-1.0-2.0-2.0-1.91.8-1.6-1.6-1.6-1.7-1.0-1.11.9-1.9-1.9
Pavlov. Cond. magazine entry number0.00.10.20.30.3-0.2-0.30.2-0.10.1-0.1-0.40.30.30.2-0.10.20.2-0.10.0-0.5-0.4-0.20.20.2
Pavlov. Cond. intertrial magazine entries0.40.71.4-0.8-0.80.8-0.9-0.50.8-0.80.8-1.0-0.8-0.8-0.70.8-0.6-0.6-1.0-0.9-1.2-1.00.6-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.60.81.2-1.1-1.11.0-0.4-1.00.7-0.70.7-0.2-1.1-1.1-1.11.0-0.9-0.9-0.6-0.8-0.1-0.31.1-1.1-1.1
Pavlov. Cond. response bias1.31.82.5-1.6-1.61.5-0.7-1.41.3-1.31.3-0.6-1.6-1.6-1.61.4-1.3-1.3-1.1-1.2-0.5-0.71.6-1.6-1.6
Time in closed arm before self-admin0.20.20.8-0.2-0.20.2-0.9-0.20.4-0.40.4-0.9-0.4-0.4-0.10.3-0.2-0.2-0.7-0.4-0.9-0.8-0.00.00.0
Time in closed arm after self-admin0.50.51.01.01.0-0.90.10.6-0.80.8-0.80.10.90.90.8-0.70.90.90.40.5-0.3-0.3-0.70.70.7
Time in open arm before self-admin0.30.30.7-0.6-0.60.6-0.3-0.70.6-0.60.6-0.3-0.5-0.5-0.60.5-0.8-0.8-0.5-0.5-0.2-0.20.5-0.5-0.5
Time in open arm after self-admin1.82.03.1-1.7-1.71.6-1.0-1.11.7-1.71.6-1.0-1.7-1.7-1.51.4-1.5-1.5-1.3-1.3-0.6-0.61.3-1.3-1.3
Bone: periosteal estimation2.24.65.82.22.2-2.22.12.4-2.22.2-2.22.02.12.12.2-2.22.12.12.22.11.91.8-2.12.12.1
Bone: periosteal perimeter1.01.82.21.41.4-1.41.21.5-1.51.5-1.51.21.31.31.3-1.31.21.21.51.31.11.0-1.31.31.3
Bone: post-yield work0.20.30.80.60.6-0.60.70.9-0.60.6-0.60.50.60.60.6-0.60.60.60.60.60.50.5-0.50.50.5
Progressive ratio test 1 active lever presses0.10.10.20.40.4-0.40.10.1-0.40.4-0.40.10.50.50.3-0.30.20.20.20.2-0.0-0.1-0.20.20.2
Progressive ratio test 1 breakpoint0.10.10.20.40.4-0.3-0.10.1-0.30.3-0.4-0.10.40.40.3-0.20.10.10.10.2-0.2-0.2-0.20.20.2
Progressive ratio test 1 inactive lever presses0.20.30.80.40.4-0.40.70.0-0.60.6-0.60.60.70.70.3-0.40.10.10.70.50.90.9-0.10.10.1
Progressive ratio test 2 active lever presses0.20.20.8-0.3-0.40.40.2-0.7-0.00.0-0.10.2-0.0-0.0-0.50.4-0.5-0.5-0.1-0.20.10.10.9-0.9-0.9
Progressive ratio test 2 breakpoint0.20.31.0-0.4-0.50.50.1-0.80.1-0.10.00.1-0.1-0.1-0.60.5-0.6-0.6-0.2-0.30.10.01.0-1.0-1.0
Progressive ratio test 2 inactive lever presses0.10.20.5-0.6-0.60.5-0.2-0.60.4-0.40.4-0.2-0.4-0.4-0.60.5-0.6-0.6-0.4-0.4-0.0-0.00.7-0.7-0.7
Incentive Sensitization - Responses1.21.82.7-1.4-1.41.4-0.9-1.51.1-1.11.1-0.9-1.2-1.2-1.51.4-1.6-1.6-1.2-1.3-0.9-0.81.7-1.7-1.7
Incentive Sensitization - Breakpoint1.01.32.2-1.3-1.31.3-0.6-1.31.0-1.01.0-0.6-1.1-1.1-1.31.2-1.4-1.4-1.0-1.1-0.6-0.51.5-1.5-1.5
Sum of active levers in priming session hrs 5-60.30.30.7-0.5-0.50.5-0.6-0.80.3-0.30.4-0.6-0.3-0.3-0.50.6-0.6-0.6-0.3-0.5-0.2-0.20.8-0.8-0.8
Progressive ratio1.11.74.31.01.0-1.11.91.0-1.11.1-1.12.01.11.11.0-1.21.01.01.41.42.12.0-0.80.80.8
Food seeking constrained by brief footshock0.10.10.2-0.2-0.30.3-0.20.20.3-0.30.3-0.2-0.2-0.2-0.30.2-0.2-0.2-0.4-0.3-0.4-0.40.4-0.4-0.4
Seeking ratio, punishment vs. effort0.50.73.0-0.4-0.50.5-1.4-0.40.5-0.50.6-1.6-0.5-0.5-0.50.7-0.4-0.4-0.9-1.0-1.7-1.70.5-0.5-0.5
Retroperitoneal fat weight0.83.55.31.71.7-1.72.31.7-2.02.0-1.92.31.81.81.6-1.81.91.92.01.92.32.3-1.41.41.4
Reaction time number correct0.10.21.10.00.0-0.10.9-0.2-0.40.4-0.30.90.10.10.0-0.20.00.00.60.41.01.00.1-0.1-0.1
Reaction time mean minus median0.10.20.4-0.6-0.60.50.4-0.50.4-0.40.40.5-0.4-0.4-0.60.4-0.5-0.5-0.3-0.20.50.60.7-0.7-0.7
Reaction time mean minus median AUC0.10.20.4-0.4-0.40.30.6-0.30.2-0.20.20.7-0.3-0.3-0.40.2-0.5-0.5-0.1-0.00.50.50.4-0.4-0.4
Reaction time num false alarms0.30.40.5-0.7-0.60.6-0.7-0.60.7-0.70.7-0.6-0.7-0.7-0.60.6-0.7-0.7-0.6-0.6-0.4-0.50.5-0.5-0.5
Reaction time num false alarms AUC0.71.11.8-1.1-1.01.1-1.3-1.01.2-1.21.1-1.2-1.1-1.1-1.01.0-1.1-1.1-1.1-1.1-1.0-1.00.8-0.8-0.8
Reaction time trials correct on left0.10.21.10.00.0-0.10.9-0.2-0.40.4-0.30.90.10.10.0-0.20.00.00.60.41.01.00.1-0.1-0.1
Reaction time trials on left0.10.21.0-0.00.0-0.00.9-0.2-0.30.3-0.30.90.10.10.0-0.2-0.0-0.00.50.41.01.00.1-0.1-0.1
Reaction time mean0.10.20.50.30.3-0.30.70.3-0.40.4-0.50.70.40.40.2-0.30.20.20.20.40.60.6-0.00.00.0
Reaction time mean AUC0.20.31.10.40.4-0.51.00.5-0.60.6-0.71.10.60.60.3-0.50.40.40.50.60.90.9-0.20.20.2
Median of all reaction times0.20.30.60.60.6-0.60.80.5-0.60.6-0.70.80.70.70.5-0.50.40.40.40.60.60.5-0.30.30.3
Reaction time omissions0.10.10.3-0.4-0.40.30.1-0.40.1-0.10.00.2-0.4-0.4-0.50.3-0.3-0.3-0.1-0.20.30.40.6-0.6-0.6
Reaction time false alarm rate0.91.22.9-0.9-0.90.9-1.7-0.81.2-1.21.1-1.7-1.0-1.0-0.81.0-1.0-1.0-1.3-1.2-1.5-1.50.7-0.7-0.7
Reaction time premature initiation rate0.10.10.4-0.1-0.10.1-0.6-0.30.4-0.40.4-0.6-0.1-0.1-0.20.30.10.1-0.3-0.3-0.3-0.40.3-0.3-0.3
Reaction time premature initiations0.00.00.20.00.0-0.00.0-0.30.0-0.00.00.10.10.1-0.00.00.20.20.20.10.40.30.2-0.2-0.2
Std. dev. reaction times0.10.20.4-0.5-0.50.40.2-0.40.4-0.40.30.2-0.4-0.4-0.50.3-0.4-0.4-0.4-0.20.20.30.6-0.6-0.6
Reaction time trials completed0.10.21.0-0.00.0-0.00.9-0.2-0.30.3-0.30.90.10.10.0-0.2-0.0-0.00.50.41.01.00.1-0.1-0.1
Reaction time trials AUC0.10.21.00.00.0-0.00.9-0.2-0.30.3-0.20.90.10.10.0-0.2-0.1-0.10.50.40.91.00.1-0.1-0.1
Run reversals in cocaine runway, females0.10.10.3-0.0-0.10.00.50.2-0.20.2-0.10.60.00.0-0.1-0.10.20.20.30.20.50.5-0.00.00.0
Run reversals in cocaine runway, males0.90.91.6-1.2-1.21.10.2-1.01.2-1.21.10.1-1.0-1.0-1.10.8-1.0-1.0-0.7-0.50.80.81.0-1.0-1.0
Latency to leave start box in cocaine runway0.30.41.80.40.4-0.3-1.0-0.5-0.50.5-0.5-1.00.60.60.20.10.50.5-0.0-0.3-1.3-1.30.3-0.3-0.3
Latency to leave start box in cocaine runway, F0.30.31.50.50.4-0.3-0.6-0.5-0.50.5-0.5-0.70.70.70.20.10.60.60.1-0.2-1.2-1.10.4-0.4-0.4
Latency to leave start box in cocaine runway, M0.20.20.30.50.6-0.5-0.50.3-0.50.5-0.5-0.30.50.50.5-0.30.50.50.30.2-0.2-0.2-0.50.50.5
Std. dev. time between licks in bursts1.52.03.71.71.7-1.60.91.3-1.91.9-1.90.81.61.61.5-1.31.31.31.41.20.40.3-1.31.31.3
Total sessions with >9 infusions0.00.00.1-0.0-0.10.10.0-0.2-0.10.1-0.10.00.00.0-0.10.1-0.2-0.2-0.0-0.1-0.1-0.20.3-0.3-0.3
Short access day 1 total inactive lever presses0.10.10.2-0.2-0.20.20.2-0.40.0-0.00.00.10.00.0-0.20.2-0.5-0.5-0.0-0.00.40.30.4-0.4-0.4
Short access day 10 total inactive lever presses0.40.91.4-1.1-1.01.0-0.9-1.11.0-1.01.1-0.9-1.0-1.0-1.01.0-1.2-1.2-0.9-0.9-0.6-0.60.8-0.8-0.8
Short access day 1 total infusions0.20.20.5-0.3-0.30.3-0.6-0.70.2-0.20.2-0.5-0.2-0.2-0.30.4-0.7-0.7-0.4-0.4-0.6-0.60.4-0.4-0.4
Short access day 10 total infusions0.60.81.8-1.1-1.01.0-0.3-0.90.9-0.90.9-0.3-0.9-0.9-1.00.8-1.3-1.3-0.8-0.7-0.2-0.20.9-0.9-0.9
Short access total infusions0.00.00.1-0.1-0.10.10.0-0.3-0.10.1-0.00.10.10.1-0.10.1-0.4-0.4-0.0-0.1-0.0-0.10.3-0.3-0.3
Short access day 1 locomotion0.10.10.20.30.2-0.2-0.3-0.3-0.40.4-0.4-0.30.30.30.1-0.0-0.2-0.20.2-0.0-0.4-0.4-0.00.00.0
Short access day 10 total locomotion0.30.50.90.91.0-0.8-0.40.4-0.80.8-0.8-0.60.80.80.9-0.60.70.70.60.3-0.5-0.5-0.70.70.7
Short access total locomotion0.40.40.80.90.9-0.8-0.10.4-0.90.9-0.8-0.10.80.80.8-0.60.40.40.70.4-0.1-0.2-0.70.70.7
One hour access (0.3 mA shock)2.63.04.1-1.7-1.71.7-1.6-1.91.6-1.61.5-1.6-1.5-1.5-1.81.8-2.0-2.0-1.6-1.7-1.6-1.62.0-2.0-2.0
Compulsive drug intake1.01.23.3-0.7-0.70.8-1.8-1.20.9-0.90.8-1.8-0.8-0.8-0.71.0-1.0-1.0-1.1-1.2-1.7-1.70.8-0.8-0.8
One hour access (shock baseline)0.60.91.6-1.1-1.21.10.1-0.70.9-0.90.90.2-0.9-0.9-1.20.9-1.1-1.1-0.7-0.60.10.11.3-1.3-1.3
Social response proportion0.60.72.00.90.9-0.90.11.4-0.70.7-0.60.00.40.41.0-0.90.80.80.60.6-0.2-0.2-1.41.41.4
Social responses0.10.20.30.50.5-0.5-0.00.5-0.50.5-0.5-0.10.40.40.5-0.40.50.50.30.3-0.3-0.3-0.50.50.5
Social time0.30.41.0-0.7-0.70.7-0.6-1.00.6-0.60.6-0.6-0.6-0.6-0.70.7-0.7-0.7-0.6-0.6-0.4-0.40.8-0.8-0.8
Soleus weight0.92.63.51.91.8-1.81.01.7-1.81.8-1.70.91.71.71.8-1.61.61.61.51.51.00.9-1.71.71.7
Bone: stiffness1.21.93.61.31.3-1.41.51.9-1.31.3-1.31.41.21.21.3-1.41.51.51.31.41.31.2-1.41.41.4
Tibialis anterior weight0.61.92.8-1.3-1.31.3-1.5-1.61.2-1.21.2-1.7-1.2-1.2-1.41.5-1.4-1.4-1.2-1.5-1.5-1.41.6-1.6-1.6
Time to tail flick, vehicle, before self-admin0.60.73.10.20.2-0.41.50.5-0.60.6-0.41.50.40.40.3-0.60.30.30.80.91.81.7-0.40.40.4
Time to tail flick, vehicle, after self-admin0.30.40.9-0.4-0.40.4-0.8-0.50.8-0.80.8-0.8-0.5-0.5-0.40.5-0.6-0.6-0.9-0.6-0.9-0.90.2-0.2-0.2
Time to tail flick, test, before self-admin0.60.61.0-0.9-0.90.9-0.6-0.50.6-0.60.7-0.4-1.0-1.0-0.90.8-1.0-1.0-0.6-0.8-0.7-0.60.8-0.8-0.8
Time to tail flick, test, after self-admin1.41.42.6-1.5-1.41.3-0.0-0.81.6-1.61.5-0.1-1.3-1.3-1.31.1-1.4-1.4-1.3-0.80.00.01.2-1.2-1.2
Delta time to tail flick, vehicle, before/after SA1.41.33.4-0.8-0.90.9-1.3-0.61.3-1.31.2-1.4-1.0-1.0-0.91.0-1.0-1.0-1.4-1.2-1.9-1.90.8-0.8-0.8
Delta time to tail flick, test, before/after SA0.40.41.10.50.5-0.51.00.7-0.10.1-0.20.90.50.50.5-0.60.50.50.30.71.01.0-0.50.50.5
Tibia length2.05.66.32.32.3-2.42.52.4-2.22.2-2.22.52.32.32.4-2.42.32.32.42.52.52.4-2.42.42.4
Ambulatory time before self-admin0.10.10.20.20.3-0.20.40.1-0.30.3-0.40.40.30.30.3-0.30.40.40.40.30.40.4-0.20.20.2
Ambulatory time after self-admin0.10.20.4-0.5-0.40.4-0.4-0.70.6-0.60.5-0.4-0.5-0.5-0.30.3-0.2-0.2-0.6-0.30.00.10.2-0.2-0.2
Bone: tissue strength0.00.00.20.20.2-0.20.10.5-0.10.1-0.1-0.00.20.20.2-0.20.10.10.10.20.0-0.0-0.40.40.4
Total heroin consumption1.31.52.1-1.4-1.31.3-1.2-1.51.2-1.21.3-1.2-1.3-1.3-1.31.2-1.5-1.5-1.2-1.2-0.8-0.81.2-1.2-1.2
Bone: trabecular number1.11.82.4-1.5-1.51.4-1.2-1.01.5-1.51.5-1.2-1.5-1.5-1.41.3-1.4-1.4-1.4-1.3-1.1-1.01.3-1.3-1.3
Bone: trabecular spacing2.22.93.91.81.8-1.81.61.8-1.61.6-1.61.51.61.61.8-1.82.02.01.61.71.41.4-1.81.81.8
Bone: trabecular thickness0.10.21.00.00.0-0.10.60.2-0.10.1-0.10.70.10.10.1-0.20.10.10.30.41.01.0-0.20.20.2
Bone: trabecular tissue density0.10.10.3-0.4-0.40.4-0.0-0.60.3-0.30.30.1-0.3-0.3-0.40.3-0.4-0.4-0.3-0.20.10.20.2-0.2-0.2
Water consumed over 24 hours0.60.91.5-0.7-0.80.8-1.1-1.00.6-0.60.6-1.2-0.7-0.7-0.80.9-1.0-1.0-0.7-1.0-1.0-1.11.2-1.2-1.2
Number of responses in last shaping day1.11.32.01.41.4-1.3-0.50.8-1.21.2-1.3-0.71.21.21.3-0.91.11.10.80.6-0.6-0.7-1.41.41.4