Rnf5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Rnf5 0.15 0.06 5.4e-12 0.1 0.13 0.1 0.11 8.8e-09 1.2e-10 9.1e-09 3.2e-09
2 NAcc intron excision ratio chr20_4150384_4151388 0.03 0.02 1.0e-04 0.02 0.02 0.02 0.02 1.5e-03 6.9e-04 4.9e-04 6.1e-04
3 IC mRNA stability Rnf5 0.31 0.12 5.6e-11 0.18 0.23 0.22 0.21 6.2e-08 5.7e-10 7.9e-10 3.5e-09
4 PL intron excision ratio chr20_4150384_4151388 0.09 0.05 1.3e-09 0.1 0.05 0.07 0.09 1.6e-10 1.6e-06 5.2e-08 3.5e-10
5 LHb mRNA stability Rnf5 0.29 0.16 6.2e-04 0.14 0.14 0.1 0.15 3.8e-04 2.6e-04 2.2e-03 2.0e-04
6 Brain mRNA stability Rnf5 0.23 0.1 0.0e+00 0.18 0.17 0.16 0.18 1.5e-16 4.4e-16 4.0e-15 1.5e-16
7 OFC mRNA stability Rnf5 0.29 0.13 2.1e-04 0.12 0.14 0.12 0.14 7.8e-04 3.0e-04 7.9e-04 3.7e-04
8 BLA mRNA stability Rnf5 0.35 0.13 2.7e-13 0.21 0.22 0.21 0.21 2.2e-11 9.3e-12 1.9e-11 2.1e-11
9 PL mRNA stability Rnf5 0.21 0.08 0.0e+00 0.22 0.18 0.21 0.22 1.5e-23 2.4e-19 5.1e-23 3.0e-24
10 NAcc mRNA stability Rnf5 0.1 0.04 2.3e-14 0.1 0.1 0.1 0.1 1.9e-14 5.2e-15 7.4e-15 1.9e-14
11 IC gene expression Rnf5 0.16 0.09 5.0e-05 0.03 0.08 0.05 0.05 1.4e-02 3.3e-04 3.4e-03 3.7e-03
12 Brain intron excision ratio chr20_4151748_4151824 0.15 0.07 5.2e-08 0.04 0.08 0.04 0.05 1.7e-04 6.8e-08 5.9e-05 9.0e-06
13 pVTA intron excision ratio chr20_4151748_4151824 0.07 0.04 4.0e-04 0.01 0.04 0.04 0.04 2.8e-02 2.6e-04 3.7e-04 4.4e-04
14 Brain intron excision ratio chr20_4151612_4151694 0.13 0.06 3.3e-07 0.03 0.06 0.02 0.03 6.7e-04 1.4e-06 3.4e-03 3.6e-04
15 PL gene expression Rnf5 0.08 0.05 4.0e-07 0.03 0.05 0.06 0.05 2.3e-04 4.6e-06 1.2e-06 8.6e-06
16 pVTA intron excision ratio chr20_4151612_4151694 0.07 0.04 5.4e-04 0.02 0.04 0.04 0.03 1.8e-02 2.5e-04 7.3e-04 2.2e-03
17 PL intron excision ratio chr20_4151612_4151694 0.05 0.03 6.8e-04 0.03 0.03 0.02 0.03 3.3e-04 4.5e-04 9.7e-04 3.0e-04
18 NAcc intron excision ratio chr20_4151748_4151824 0.05 0.03 3.0e-05 0.02 0.03 0.03 0.04 1.9e-04 2.2e-05 7.0e-06 1.1e-06
19 NAcc intron excision ratio chr20_4151612_4151694 0.05 0.03 2.9e-05 0.02 0.03 0.03 0.04 1.9e-04 3.2e-05 2.7e-05 2.9e-06
20 NAcc gene expression Rnf5 0.2 0.09 0.0e+00 0.12 0.16 0.15 0.15 1.1e-17 9.2e-23 1.7e-21 4.5e-22
21 Adipose gene expression Rnf5 0.03 0.02 4.2e-03 0 0 -0 -0 2.6e-01 9.1e-02 9.2e-01 6.1e-01
22 BLA intron excision ratio chr20_4151748_4151824 0.09 0.06 6.4e-03 0.01 0.02 -0 0.02 8.7e-02 4.3e-02 6.4e-01 4.4e-02
23 pVTA gene expression Rnf5 0.16 0.07 1.9e-10 0.08 0.12 0.1 0.1 1.1e-06 4.2e-10 3.9e-08 2.1e-08
24 PL intron excision ratio chr20_4151748_4151824 0.05 0.04 1.1e-03 0.02 0.03 0.02 0.03 1.0e-03 5.9e-04 2.9e-03 5.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.81.53.50.3-0.60.0-1.11.50.0-1.10.60.2-0.9-1.7-1.9-1.61.81.41.71.5-1.51.5-0.7-0.9-1.1-1.0-1.3
Area under the delay curve0.40.61.6-0.10.50.00.5-0.6-0.20.6-0.20.10.61.01.01.0-1.0-1.3-1.0-0.70.9-0.90.90.91.01.00.6
BMI with tail1.86.211.6-2.72.0-3.12.4-2.83.4-3.1-3.1-3.4-3.2-0.2-2.4-2.92.41.82.81.2-2.52.3-0.9-2.9-1.6-2.0-1.4
BMI without tail0.63.210.0-2.92.7-2.62.8-3.22.5-1.4-2.6-2.3-1.82.50.5-0.4-0.5-1.00.3-1.4-0.40.11.1-0.50.90.51.0
Body weight1.14.718.6-3.02.3-3.03.6-4.33.4-1.7-3.8-3.5-2.11.8-0.0-0.90.1-0.00.8-0.3-1.51.2-0.5-1.9-0.5-1.0-0.2
Weight adjusted by age0.20.51.8-0.90.3-0.51.1-1.20.70.2-0.8-0.6-0.11.41.10.6-1.1-0.7-0.6-0.7-0.30.2-0.4-0.20.0-0.2-0.2
Bone surface0.10.10.40.4-0.60.4-0.40.50.10.30.30.20.2-0.4-0.10.00.10.40.00.1-0.30.3-0.6-0.2-0.4-0.4-0.0
Bone volume0.10.30.8-0.1-0.2-0.2-0.20.30.4-0.50.0-0.2-0.5-0.5-0.7-0.70.70.60.70.5-0.90.9-0.5-0.5-0.5-0.5-0.4
Breakpoint value in progressive ratio session0.10.20.70.6-0.70.6-0.80.8-0.50.50.60.50.5-0.30.10.3-0.10.3-0.3-0.3-0.20.30.00.30.10.10.4
Number of licking bursts0.30.92.41.6-1.51.4-1.00.4-1.01.51.01.21.5-0.60.71.1-0.7-0.2-1.1-0.20.8-0.7-0.50.6-0.10.00.4
Context. condit. distance diff. score3.84.612.13.2-3.52.9-3.32.9-2.51.72.82.41.8-2.9-0.50.30.62.2-0.11.9-0.50.7-2.4-0.2-1.9-1.6-1.7
Locomotion velocity, session 11.82.04.21.6-1.21.9-1.71.6-1.91.82.02.01.80.11.41.6-1.4-1.1-1.5-0.71.3-1.20.31.50.70.90.6
Locomotion distance, session 10.50.61.50.6-0.50.4-1.11.2-0.5-0.40.80.5-0.2-1.2-1.1-0.81.00.80.91.0-0.60.7-0.4-0.4-0.6-0.5-0.9
Locomotion velocity, session 20.30.41.01.0-0.80.9-0.80.7-1.00.80.80.80.9-0.50.30.6-0.3-0.1-0.6-0.10.6-0.50.00.50.10.20.2
Locomotion distance, session 21.01.44.21.0-1.10.5-1.20.9-0.5-0.40.60.3-0.2-2.0-1.5-1.11.51.61.21.8-1.11.2-1.2-1.0-1.5-1.3-1.7
Locomotion velocity, session 30.40.51.6-0.61.0-0.50.6-0.6-0.1-0.2-0.2-0.1-0.11.00.50.3-0.6-1.1-0.3-0.90.6-0.71.30.71.11.00.9
Locomotion distance, session 30.40.51.61.0-0.70.8-1.31.1-1.20.11.21.00.4-1.0-0.5-0.20.50.70.30.6-0.00.10.00.3-0.20.0-0.5
Stereotopy head waving bouts, day 30.50.61.40.10.10.20.6-0.70.21.0-0.4-0.10.80.81.21.1-1.2-1.1-1.2-0.80.8-0.80.20.50.50.40.8
Stereotopy head waving duration, day 31.11.33.7-0.20.50.10.7-0.70.01.1-0.20.10.81.61.81.5-1.8-1.9-1.5-1.51.2-1.30.71.01.11.01.3
Locomotion velocity, session 73.43.810.11.7-2.01.1-2.22.0-1.0-0.61.50.9-0.2-3.2-2.3-1.72.32.81.82.9-1.71.9-1.9-1.3-2.1-1.9-2.6
Locomotion distance, session 71.92.47.02.0-1.91.7-2.62.2-1.90.22.21.80.6-2.5-1.4-0.71.31.80.81.9-0.60.8-0.8-0.1-1.0-0.7-1.6
Stereotopy head waving bouts, day 73.03.58.0-0.00.80.40.5-0.3-0.81.40.40.81.32.12.32.1-2.3-2.8-2.2-2.52.4-2.42.22.22.42.42.4
Stereotopy head waving duration, day 71.62.05.1-0.41.0-0.10.9-0.6-0.20.8-0.20.20.71.81.71.5-1.7-2.3-1.6-2.01.8-1.91.71.51.81.81.9
Locomotion velocity, session 82.42.96.92.6-2.52.6-2.01.5-2.52.62.02.12.6-0.91.41.9-1.3-0.1-1.8-0.21.3-1.1-1.01.0-0.3-0.10.2
Locomotion distance, session 84.26.115.93.1-3.62.6-3.42.7-2.10.82.41.81.1-4.0-1.8-0.81.83.21.03.0-1.51.7-3.2-1.2-2.9-2.5-2.8
Degree of sensitization distance0.30.41.41.0-1.20.9-0.80.4-0.50.80.60.60.8-0.70.10.4-0.10.5-0.40.30.1-0.0-0.8-0.0-0.5-0.4-0.2
Degree of sensitization stereotypy2.12.34.40.30.50.6-0.10.3-1.11.20.81.11.21.41.71.7-1.8-2.1-1.7-1.92.0-2.01.92.02.02.02.0
Conditioned locomotion0.50.61.3-0.3-0.2-0.50.6-0.81.1-0.4-0.9-0.9-0.5-0.4-0.6-0.60.71.00.60.9-0.90.9-1.1-1.1-1.1-1.1-0.9
Cocaine response after cond. corrected1.92.95.90.5-1.2-0.2-0.50.20.7-1.0-0.4-0.8-0.8-2.3-2.2-1.82.22.41.82.2-1.81.9-2.1-2.0-2.3-2.2-2.2
Cocaine response after cond. not corrected0.20.31.10.4-0.80.10.1-0.30.30.1-0.5-0.40.1-0.8-0.4-0.20.40.80.20.5-0.30.4-1.1-0.8-1.0-0.9-0.6
Cocaine response before conditioning4.45.311.0-0.71.3-0.11.6-1.4-0.31.7-0.50.21.43.33.32.8-3.3-3.0-2.9-3.32.6-2.82.22.22.62.53.0
Saline control response2.94.111.4-3.03.4-2.63.0-2.51.9-1.4-2.3-1.8-1.63.10.80.0-0.9-2.3-0.1-2.10.7-1.02.40.42.11.71.7
Bone: connectivity density1.52.34.40.4-0.90.1-1.11.60.3-1.10.4-0.1-0.9-2.1-2.1-1.82.12.01.92.0-1.81.9-1.6-1.5-1.8-1.7-1.8
Bone: cortical apparent density1.32.14.8-2.01.9-2.22.0-1.72.2-2.0-2.1-2.0-2.00.6-1.1-1.51.10.11.40.3-0.90.70.5-1.1-0.1-0.2-0.4
Bone: cortical area0.10.10.3-0.10.2-0.20.5-0.60.40.2-0.5-0.20.20.40.40.3-0.4-0.3-0.4-0.50.5-0.50.20.20.30.30.5
Bone: cortical porosity5.96.414.90.50.61.2-0.20.3-1.82.21.41.92.12.63.33.1-3.3-3.9-3.1-2.92.9-3.02.73.23.23.22.7
Bone: cortical porosity5.66.213.90.90.11.6-0.60.5-1.92.51.72.12.42.33.33.2-3.3-3.7-3.1-2.62.8-2.92.23.12.82.82.5
Bone: cortical thickness0.71.23.5-1.61.9-1.71.5-1.41.5-1.5-1.6-1.4-1.40.8-0.7-0.90.6-0.30.8-0.3-0.10.01.1-0.30.60.50.3
Bone: cortical thickness2.02.46.0-2.22.4-2.42.1-2.21.9-2.2-2.2-2.1-2.10.8-1.1-1.51.0-0.11.3-0.2-0.80.71.1-0.90.30.20.1
Bone: cortical tissue density1.21.94.4-1.91.8-2.11.9-1.62.1-1.9-2.0-1.9-1.90.6-1.0-1.41.00.01.30.3-0.80.70.5-1.0-0.0-0.2-0.4
Condit. Reinf. active minus inactive responses1.01.22.20.7-0.20.9-0.70.8-1.30.91.11.31.10.51.11.1-1.1-1.3-1.1-0.81.2-1.21.21.51.21.30.9
Condit. Reinf. active-inactive response ratio0.70.72.1-0.71.1-0.50.8-0.50.1-0.1-0.3-0.1-0.01.20.70.5-0.8-1.3-0.6-1.10.8-0.91.50.81.31.21.1
Condit. Reinf. active responses0.20.20.90.5-0.30.5-0.70.7-0.90.10.80.80.3-0.3-0.00.1-0.0-0.0-0.10.20.2-0.10.50.50.30.4-0.0
Condit. Reinf. inactive responses0.81.02.50.4-0.50.1-1.00.9-0.4-0.90.60.3-0.6-1.5-1.6-1.31.51.61.41.4-1.01.1-0.5-0.7-0.8-0.7-1.2
Incentive salience index mean1.01.33.61.9-1.71.7-1.81.8-1.81.21.71.71.4-1.30.10.6-0.10.4-0.60.50.5-0.3-0.40.6-0.3-0.0-0.4
Condit. Reinf. lever presses2.74.110.22.7-3.22.2-2.82.6-1.71.02.01.61.2-3.2-1.2-0.41.32.70.52.2-0.91.2-2.5-0.8-2.3-1.9-2.1
Condit. Reinf. active minus inactive responses0.81.22.8-0.40.60.00.7-0.6-0.30.8-0.10.20.61.61.71.3-1.7-1.4-1.4-1.51.1-1.11.01.11.31.21.4
Condit. Reinf. active-inactive response ratio0.81.33.70.10.00.50.4-0.3-0.61.30.20.51.11.51.91.7-1.9-1.4-1.7-1.51.2-1.20.61.11.00.91.3
Condit. Reinf. active responses0.40.51.2-0.30.50.00.3-0.2-0.30.50.10.20.31.11.10.8-1.1-0.9-0.8-1.10.7-0.70.80.81.00.91.0
Condit. Reinf. inactive responses0.20.30.8-0.80.9-0.80.6-0.70.5-0.8-0.6-0.7-0.80.2-0.5-0.60.40.00.5-0.1-0.20.20.5-0.20.20.20.2
Condit. Reinf. lever presses0.71.01.70.5-0.20.9-0.60.6-1.20.91.21.30.90.71.21.1-1.2-0.9-1.0-1.01.0-1.00.91.31.11.11.0
Condit. Reinf. lever reinforcers received0.60.91.8-0.00.30.30.1-0.0-0.70.80.40.60.71.21.31.2-1.3-1.1-1.1-1.31.0-1.01.01.21.21.11.3
Conditioned reinforcement - actives0.00.10.6-0.30.0-0.2-0.1-0.20.1-0.40.1-0.2-0.50.0-0.2-0.40.20.40.40.3-0.70.7-0.0-0.2-0.1-0.2-0.4
Conditioned reinforcement - inactives0.00.10.3-0.30.1-0.00.1-0.1-0.1-0.10.30.1-0.20.50.30.1-0.3-0.50.0-0.1-0.30.30.20.20.20.1-0.1
Conditioned locomotion0.10.10.50.2-0.50.4-0.70.5-0.40.20.50.40.2-0.00.20.2-0.20.1-0.10.3-0.30.3-0.30.1-0.2-0.1-0.6
Patch foraging indifference point 0 sec0.82.25.6-2.42.3-2.12.1-2.31.7-1.3-1.9-1.6-1.42.20.4-0.2-0.5-1.30.1-1.3-0.1-0.11.60.11.31.00.8
Patch foraging indifference point AUC0.61.53.80.00.40.2-0.0-0.1-0.50.90.10.50.91.31.41.4-1.4-1.6-1.4-1.81.9-2.01.41.41.51.51.6
Delay disc. indifference point, 0s delay0.20.20.60.7-0.80.6-0.20.2-0.30.50.30.30.6-0.50.10.2-0.0-0.2-0.30.4-0.30.4-0.6-0.1-0.5-0.4-0.4
Delay disc. indifference point, 16s delay0.30.41.3-0.71.1-0.60.7-0.60.2-0.3-0.4-0.2-0.20.90.40.2-0.4-0.9-0.3-0.50.7-0.71.10.50.90.90.4
Delay disc. indifference point, 2s delay1.21.43.70.5-0.40.9-0.10.1-0.91.60.50.91.41.11.91.8-1.9-1.4-1.8-0.91.1-1.00.61.31.11.10.8
Delay disc. indifference point, 24s delay1.21.94.3-0.51.0-0.10.8-0.9-0.40.7-0.10.40.72.01.81.5-1.8-2.1-1.6-1.21.8-1.91.71.51.91.91.0
Delay disc. indifference point, 4s delay0.91.02.3-0.50.8-0.31.0-1.10.20.6-0.7-0.20.51.51.41.1-1.4-1.5-1.2-1.30.6-0.61.00.91.21.11.2
Delay disc. indifference point, 8s delay0.20.31.00.10.40.10.3-0.2-0.20.4-0.10.20.50.50.60.6-0.6-1.0-0.7-0.50.8-0.80.70.70.70.80.3
Indifference point function ln k0.20.61.41.1-0.81.1-0.50.6-1.11.10.91.01.2-0.20.70.9-0.7-0.2-0.9-0.20.5-0.4-0.00.70.20.30.5
Indifference point function log k0.20.61.41.1-0.81.1-0.50.6-1.11.10.91.01.2-0.20.70.9-0.7-0.2-0.9-0.20.5-0.4-0.00.70.20.30.5
Patch foraging total patch changes 0 sec0.82.36.0-2.42.4-2.22.2-2.41.7-1.3-2.0-1.6-1.52.20.4-0.3-0.5-1.40.1-1.3-0.1-0.11.70.11.41.10.8
Patch foraging total patch changes 12 sec1.21.63.8-1.92.0-1.71.5-1.51.2-0.8-1.5-1.2-1.01.90.50.0-0.5-1.2-0.1-1.60.6-0.81.60.41.41.21.2
Patch foraging total patch changes 18 sec1.33.17.3-2.52.4-2.71.9-2.12.5-2.6-2.3-2.3-2.60.7-1.6-2.01.50.21.8-0.2-1.00.90.9-1.30.1-0.1-0.2
Patch foraging total patch changes 24 sec0.30.93.0-1.41.5-1.50.5-0.41.0-1.7-0.9-1.0-1.60.3-1.1-1.31.0-0.11.30.2-0.60.50.9-0.50.30.2-0.5
Patch foraging total patch changes 6 sec1.11.84.9-2.22.2-2.01.9-1.61.6-1.4-1.7-1.4-1.41.90.2-0.4-0.2-1.40.3-1.20.0-0.21.60.01.20.90.6
Patch foraging time to switch 0 sec1.45.28.9-1.20.5-1.71.1-0.82.2-2.5-1.6-2.2-2.4-1.6-2.8-2.92.82.62.92.5-3.02.9-1.9-2.8-2.4-2.5-2.4
Patch foraging water rate 0 sec0.00.20.7-0.40.3-0.30.5-0.70.30.1-0.5-0.3-0.00.60.40.3-0.4-0.8-0.3-0.40.3-0.30.40.10.30.30.1
Patch foraging water rate 12 sec0.00.20.6-0.50.5-0.60.2-0.40.6-0.8-0.4-0.4-0.7-0.0-0.6-0.60.6-0.10.60.1-0.10.00.5-0.20.20.2-0.0
Patch foraging water rate 18 sec0.10.30.9-0.80.6-0.80.8-1.00.6-0.6-0.8-0.8-0.60.6-0.1-0.30.1-0.60.2-0.00.2-0.20.5-0.20.30.2-0.1
Patch foraging water rate 24 sec0.20.31.0-0.70.7-0.70.6-1.00.6-0.6-0.6-0.7-0.70.3-0.3-0.40.3-0.00.4-0.4-0.40.30.3-0.20.20.10.5
Patch foraging water rate 6 sec0.20.30.6-0.60.5-0.80.5-0.50.7-0.8-0.7-0.8-0.70.0-0.6-0.60.6-0.00.60.2-0.10.10.3-0.4-0.0-0.1-0.2
Seeking ratio, delayed vs. immediate footshock1.72.47.7-1.11.7-1.11.5-0.90.60.2-1.3-0.60.12.11.31.0-1.4-1.2-1.2-2.81.8-1.92.21.22.01.92.7
Distance traveled before self-admin0.61.23.7-0.1-0.6-0.4-0.1-0.20.9-0.7-0.7-0.9-0.7-1.1-1.2-1.11.31.91.10.6-1.51.5-1.5-1.5-1.6-1.6-0.8
Distance traveled after self-admin0.30.61.9-0.90.7-0.91.1-1.40.8-0.0-1.2-0.9-0.21.10.60.3-0.6-0.4-0.4-1.20.7-0.80.4-0.00.40.31.2
Extensor digitorum longus weight0.10.41.50.7-1.20.7-0.60.5-0.40.70.50.40.5-0.60.10.2-0.10.9-0.20.3-0.40.4-1.2-0.3-0.9-0.8-0.4
Bone: elastic displacement0.50.62.7-0.40.7-0.20.30.2-0.30.00.20.30.01.10.70.5-0.8-1.6-0.5-0.70.7-0.81.30.91.21.20.5
Bone: elastic work0.10.20.7-0.50.5-0.40.5-0.10.3-0.1-0.3-0.2-0.10.70.40.2-0.4-0.8-0.3-0.40.2-0.30.60.30.50.50.2
Bone: endosteal estimation0.61.55.10.6-1.00.90.4-0.8-0.12.1-0.10.21.61.22.32.1-2.1-0.7-2.1-1.50.6-0.7-0.80.60.1-0.01.2
Bone: endosteal perimeter0.51.34.31.7-2.11.6-0.90.4-0.62.00.80.81.8-0.51.11.4-1.00.5-1.4-0.30.6-0.5-1.50.2-0.8-0.70.2
Epididymis fat weight4.020.342.9-5.64.7-6.04.1-4.35.8-6.5-5.1-5.9-6.50.2-4.7-5.74.62.45.52.4-4.44.00.0-4.3-1.6-2.2-2.4
Delta time in closed arm before/after self-admin0.50.41.3-0.3-0.3-0.20.2-0.30.7-0.3-0.4-0.6-0.5-0.3-0.4-0.50.50.40.60.7-1.21.1-1.1-0.9-0.9-1.0-0.9
Delta time in open arm before/after self-admin0.10.10.3-0.40.6-0.20.2-0.2-0.1-0.20.00.0-0.20.60.30.1-0.3-0.2-0.0-0.20.2-0.30.50.30.60.50.3
Diff in mean of infusions in LGA sessions1.01.85.91.3-1.40.7-1.31.4-0.3-0.30.80.40.0-2.4-1.8-1.21.82.11.21.8-0.91.1-1.3-1.0-1.6-1.3-1.3
Delay discount exponential model param0.70.92.30.1-0.6-0.1-0.50.60.3-0.70.2-0.3-0.7-1.2-1.3-1.21.31.51.31.0-1.11.1-1.1-1.1-1.3-1.3-0.8
Extinction: sum of active levers before priming0.40.51.81.1-1.31.0-1.30.9-0.70.80.80.70.8-0.80.10.3-0.10.7-0.30.70.4-0.4-0.70.0-0.6-0.5-0.6
Active lever presses in extinction session 60.10.10.5-0.2-0.10.0-0.40.40.0-0.40.4-0.0-0.4-0.2-0.3-0.40.30.10.50.3-0.50.5-0.1-0.2-0.2-0.3-0.7
Bone: final force1.52.56.2-2.01.6-2.22.2-2.52.3-1.8-2.5-2.4-1.90.5-1.0-1.41.00.71.30.2-1.41.3-0.2-1.5-0.6-0.8-0.4
Bone: final moment1.11.84.6-1.81.4-1.91.9-2.11.9-1.5-2.0-2.0-1.60.6-0.7-1.10.70.41.00.1-1.21.1-0.1-1.2-0.4-0.6-0.3
Food consumed during 24 hour testing period0.51.12.6-0.1-0.5-0.40.4-0.80.9-0.5-0.9-0.9-0.5-0.9-0.9-0.91.01.50.81.1-1.21.2-1.6-1.5-1.5-1.6-1.2
Glucose3.04.711.53.2-3.33.4-2.51.9-2.73.32.72.73.2-1.01.92.4-1.8-0.2-2.3-0.01.2-1.0-1.51.2-0.5-0.3-0.1
Heart weight1.52.47.4-0.71.0-0.11.3-1.30.01.1-0.40.00.82.52.41.9-2.4-2.7-1.9-1.91.4-1.51.21.41.71.51.6
Delay discount hyperbolic model param0.91.22.70.0-0.6-0.1-0.50.60.4-0.90.1-0.4-0.9-1.4-1.5-1.41.51.71.51.1-1.11.1-1.2-1.3-1.4-1.4-1.1
Intermittent access intake day 1-15 change0.10.41.2-0.20.6-0.30.5-0.60.00.1-0.30.00.20.60.40.4-0.4-0.8-0.5-0.61.1-1.10.90.50.80.81.0
Intermittent access intake escalation0.21.13.1-0.91.5-0.91.0-0.90.4-0.3-0.7-0.3-0.21.30.50.4-0.6-1.5-0.5-1.21.2-1.31.80.81.41.41.5
Intermittent access intake escalation 20.40.62.00.30.10.3-0.0-0.4-0.50.60.30.50.60.50.70.8-0.8-1.3-0.8-0.61.4-1.40.90.90.80.91.0
Intermitt. access day 1 inactive lever presses0.10.73.11.1-1.71.0-0.60.0-0.40.80.40.40.7-1.2-0.10.10.20.8-0.10.8-0.40.5-1.8-0.6-1.3-1.3-0.5
Intermitt. access day 15 inactive lever presses0.00.10.2-0.30.1-0.20.4-0.40.30.0-0.3-0.3-0.10.40.30.1-0.2-0.2-0.1-0.10.1-0.1-0.2-0.2-0.1-0.20.0
Intermitt. access escalation Index0.51.55.11.5-1.60.9-1.31.7-0.50.20.80.60.4-2.2-1.3-0.71.32.30.71.3-0.81.0-1.3-0.7-1.4-1.2-0.8
Intermittent access day 1 total infusions0.30.93.71.0-1.21.3-1.81.9-1.40.51.81.40.5-0.70.00.10.00.30.00.5-0.70.8-0.30.4-0.1-0.1-0.7
Intermittent access day 15 total infusions0.10.31.1-0.20.50.0-0.20.5-0.5-0.00.50.5-0.00.60.30.3-0.4-0.9-0.2-0.50.2-0.21.10.80.90.90.6
Intermittent access terminal intake (last 3 days)0.30.61.8-0.20.50.2-0.30.3-0.60.30.70.70.21.00.90.7-0.9-1.3-0.6-0.80.5-0.51.21.01.21.10.7
Intermittent access total infusions0.30.30.90.1-0.00.4-0.60.8-0.80.21.00.80.20.50.60.4-0.6-0.8-0.3-0.4-0.00.00.60.80.70.70.2
Intermittent access day 1 locomotion0.20.41.9-0.1-0.2-0.1-0.50.50.0-0.50.3-0.0-0.5-0.4-0.6-0.60.60.70.70.7-1.41.4-0.4-0.4-0.4-0.4-0.8
Intermittent access day 15 total locomotion0.10.31.0-0.90.9-0.90.9-1.00.8-0.6-1.0-0.8-0.60.70.0-0.2-0.0-0.10.1-0.30.0-0.10.4-0.20.20.20.1
Intermittent access total locomotion0.20.20.6-0.80.7-0.60.5-0.70.4-0.6-0.4-0.4-0.60.60.0-0.2-0.0-0.10.2-0.2-0.30.20.50.00.40.3-0.0
Intermittent access standard deviation0.31.54.3-2.01.8-1.81.8-2.11.6-1.1-1.7-1.5-1.31.60.2-0.4-0.2-1.40.3-0.90.0-0.20.8-0.30.70.40.5
Left kidney weight0.65.218.6-3.43.1-3.34.1-4.33.3-1.9-3.7-3.4-2.22.50.2-0.8-0.2-0.80.6-0.9-1.00.70.6-1.20.4-0.10.6
Right kidney weight0.75.216.7-3.32.7-3.23.9-4.13.6-2.1-3.7-3.6-2.51.8-0.4-1.30.50.11.1-0.2-1.61.3-0.3-1.9-0.4-0.8-0.1
Cocaine induced anxiety0.20.41.50.5-0.70.2-0.3-0.00.2-0.0-0.1-0.20.0-1.1-0.7-0.50.71.20.50.4-0.70.8-1.0-0.7-1.0-1.0-0.4
Post-drug Anxiety0.10.10.6-0.1-0.0-0.20.4-0.50.4-0.1-0.4-0.4-0.1-0.2-0.2-0.20.20.70.20.2-0.40.4-0.5-0.5-0.5-0.5-0.0
Baseline Anxiety0.10.21.1-0.40.5-0.30.6-0.40.20.0-0.3-0.2-0.00.70.50.3-0.5-0.3-0.3-0.01.0-1.10.40.20.50.40.2
Tail length1.26.317.0-0.40.60.31.6-2.1-0.22.5-0.60.42.03.54.13.5-4.0-3.3-3.6-3.32.2-2.41.62.32.52.32.8
Length with tail0.73.09.1-0.80.5-0.32.1-2.70.71.6-1.5-0.71.12.83.02.4-2.9-2.0-2.5-2.00.9-1.10.20.81.10.91.5
Length without tail0.63.38.4-1.40.2-1.62.2-2.92.4-1.0-2.7-2.7-1.3-0.0-0.6-1.10.81.41.01.0-2.12.0-2.4-2.4-2.0-2.3-1.4
Times rat made contact with spout0.80.94.5-0.61.3-0.60.4-0.1-0.3-0.5-0.10.1-0.30.90.20.1-0.3-1.7-0.2-1.00.9-0.92.11.11.61.61.2
Lifetime Intake0.20.30.70.0-0.00.4-0.50.8-0.70.20.80.70.20.50.50.4-0.5-0.7-0.3-0.3-0.20.20.50.70.60.60.1
Liver weight, left0.20.41.50.5-0.90.50.2-1.20.11.0-0.4-0.20.8-0.10.70.7-0.60.4-0.7-0.2-0.30.3-1.2-0.4-0.8-0.80.0
Liver weight, right0.40.82.91.1-1.31.1-0.3-0.2-0.71.70.30.41.50.01.31.3-1.20.2-1.3-0.30.00.1-1.10.2-0.5-0.40.2
Locomotor activity1.21.94.5-0.20.60.00.7-1.0-0.31.2-0.40.31.01.92.01.8-2.0-1.1-1.9-2.11.5-1.61.21.41.61.51.9
Locomotor testing distance0.10.31.1-0.1-0.10.00.1-0.6-0.20.7-0.30.10.50.81.00.9-1.00.3-0.9-0.90.3-0.40.20.40.50.40.6
Locomotor testing rearing0.10.21.1-0.4-0.3-0.40.3-0.40.50.0-0.7-0.6-0.20.30.2-0.0-0.11.0-0.0-0.2-0.60.5-0.7-0.5-0.5-0.6-0.1
Locomotion in novel chamber0.10.10.2-0.40.3-0.50.3-0.40.3-0.4-0.5-0.4-0.30.1-0.2-0.30.20.20.2-0.0-0.0-0.00.2-0.10.10.00.1
Locomotion in novel chamber post-restriction0.30.82.1-1.41.2-1.31.1-1.51.4-1.0-1.4-1.3-1.10.8-0.2-0.60.20.10.5-0.0-1.00.90.0-0.7-0.1-0.3-0.3
Fecal boli incidents, locomotor time 10.41.02.70.1-0.80.3-1.10.8-0.1-0.40.70.1-0.6-0.9-0.8-0.90.91.61.11.3-1.31.3-1.4-0.9-1.2-1.3-1.5
Change in fecal boli incidents, locomotor task0.40.41.10.4-0.40.20.5-0.50.10.9-0.50.10.90.30.80.9-0.8-0.6-1.0-0.71.0-1.0-0.10.30.10.20.7
Time >=10cm from walls, locomotor time 11.21.53.0-0.5-0.2-0.81.2-1.61.6-0.6-1.6-1.6-0.7-0.5-0.8-0.90.81.50.81.0-1.21.2-1.7-1.7-1.6-1.7-1.0
Bouts of movement, locomotor time 10.10.10.30.6-0.20.3-0.10.1-0.30.20.30.40.4-0.4-0.10.10.10.2-0.2-0.20.4-0.30.30.40.20.40.4
Total resting periods, locomotor time 10.10.10.40.6-0.30.5-0.30.2-0.50.40.40.60.5-0.40.00.3-0.00.0-0.3-0.00.4-0.40.10.40.10.30.2
Rest time, locomotor task time 10.20.40.80.6-0.60.9-0.50.8-0.90.90.90.80.70.20.80.8-0.8-0.3-0.7-0.00.2-0.2-0.30.50.10.10.2
Distance moved, locomotor task time 10.10.41.2-0.80.8-0.91.0-1.00.9-0.6-1.1-0.9-0.50.5-0.1-0.20.1-0.20.1-0.4-0.0-0.00.5-0.20.20.20.1
Vertical activity count, locomotor time 10.21.23.7-1.41.4-1.71.8-1.61.8-1.4-1.9-1.7-1.30.5-0.8-1.00.70.40.8-0.0-0.1-0.00.3-0.80.0-0.1-0.1
Time >=10cm from walls, locomotor time 20.10.31.3-0.30.1-0.31.0-1.10.70.3-1.0-0.70.20.60.60.5-0.6-0.4-0.60.5-0.30.3-0.6-0.3-0.2-0.3-0.7
Bouts of movement, locomotor time 20.31.12.40.10.40.30.4-0.0-0.60.90.20.70.91.11.31.2-1.3-1.2-1.3-0.81.5-1.51.21.31.41.41.3
Total resting periods, locomotor time 20.52.04.30.60.00.90.00.5-1.21.50.71.31.51.21.81.8-1.8-1.4-1.8-1.12.1-2.11.21.81.61.61.6
Rest time, locomotor task time 20.60.93.41.3-1.61.0-0.90.7-0.50.70.60.50.7-1.6-0.5-0.20.61.20.21.0-0.10.2-1.8-0.7-1.5-1.4-0.7
Distance moved, locomotor task time 20.71.02.1-1.51.3-1.51.4-1.21.3-1.3-1.4-1.4-1.30.7-0.5-0.80.4-0.50.70.2-0.80.70.4-0.70.1-0.0-0.9
Vertical activity count, locomotor time 20.30.72.0-1.21.0-1.21.2-1.41.1-1.0-1.2-1.2-1.00.6-0.3-0.50.2-0.20.50.4-0.60.50.2-0.60.0-0.1-0.8
Light reinforcement 10.52.44.1-1.00.6-1.61.4-1.22.0-1.7-1.9-2.0-1.6-1.0-1.9-1.91.91.51.81.1-1.41.4-1.0-2.0-1.5-1.5-1.1
Light reinforcement 20.71.53.0-0.3-0.4-0.70.3-0.61.1-1.0-1.1-1.3-0.9-1.2-1.4-1.31.41.61.31.3-1.21.2-1.5-1.7-1.7-1.7-1.4
Bone: marrow area0.61.45.00.4-0.90.70.6-1.00.12.0-0.20.01.51.32.22.0-2.1-0.7-2.0-1.50.6-0.6-0.80.50.1-0.11.2
Bone: maximum diameter0.71.33.71.8-1.81.7-1.21.0-1.11.91.11.31.9-0.51.11.4-1.0-0.1-1.4-0.40.9-0.8-0.80.6-0.3-0.10.4
Bone: maximum force0.61.23.3-1.30.9-1.41.5-1.81.8-1.1-1.6-1.6-1.20.4-0.6-0.90.60.50.80.2-1.21.1-0.4-1.1-0.5-0.7-0.4
Bone: maximum moment0.40.72.0-1.10.6-1.01.1-1.41.4-0.8-1.2-1.2-0.90.4-0.3-0.50.30.20.50.1-1.00.9-0.3-0.8-0.4-0.5-0.3
Mean time between licks in bursts0.42.45.82.3-2.32.4-2.01.6-2.02.32.12.12.2-0.71.21.7-1.20.3-1.6-0.21.0-0.9-0.91.0-0.2-0.00.4
Mean num. licks in bursts0.41.24.5-1.82.1-1.71.2-0.50.9-1.6-1.0-1.1-1.61.2-0.4-0.90.4-0.80.8-0.4-0.20.11.60.01.00.90.4
Cd content in liver2.62.96.0-0.5-0.3-0.7-0.30.21.1-1.7-0.4-1.1-1.7-1.6-2.2-2.22.21.72.32.1-2.22.2-1.7-2.1-2.0-2.1-2.4
Co content in liver1.41.73.2-1.61.2-1.71.5-1.41.8-1.7-1.7-1.8-1.80.3-1.0-1.41.00.61.40.6-1.31.2-0.3-1.4-0.7-0.9-0.9
Cu content in liver0.30.42.2-0.51.0-0.70.3-0.2-0.4-1.0-0.2-0.0-0.70.1-0.6-0.60.5-0.50.5-0.30.3-0.31.50.40.80.90.6
Fe content in liver0.80.92.2-1.41.0-1.30.9-0.91.4-1.4-1.1-1.2-1.50.3-0.9-1.20.90.21.20.4-1.00.9-0.1-1.0-0.3-0.5-0.4
K content in liver0.40.41.30.8-0.90.6-0.90.8-0.70.00.70.60.2-1.2-0.7-0.40.70.90.40.6-0.30.4-0.6-0.3-0.7-0.5-0.4
Mg content in liver1.31.54.42.1-2.11.7-1.71.5-1.71.31.41.41.4-1.7-0.10.50.11.2-0.40.50.2-0.0-1.20.1-1.0-0.7-0.2
Mn content in liver1.41.65.42.1-2.31.8-1.60.8-1.01.41.10.91.4-1.8-0.10.40.21.2-0.41.0-0.30.4-2.0-0.4-1.6-1.3-1.0
Na content in liver0.40.51.9-0.30.7-0.40.4-0.6-0.0-0.1-0.30.10.10.50.20.2-0.2-0.7-0.3-1.11.0-1.01.30.71.01.11.4
Rb content in liver0.91.12.20.5-1.10.3-0.71.0-0.2-0.40.30.0-0.4-1.4-1.1-1.01.21.51.01.3-1.31.3-1.5-1.1-1.4-1.4-1.2
Se content in liver3.13.68.02.4-1.72.4-1.51.3-2.52.71.92.32.8-0.12.02.4-2.0-0.9-2.4-1.22.1-1.90.42.00.91.21.4
Sr content in liver0.10.10.70.1-0.50.3-0.4-0.00.40.30.3-0.10.1-0.10.10.1-0.00.10.00.2-0.30.3-0.9-0.4-0.5-0.7-0.6
Zn content in liver0.20.30.80.6-0.80.5-0.60.5-0.50.30.50.30.2-0.7-0.2-0.10.30.60.20.5-0.40.4-0.9-0.4-0.8-0.8-0.6
Bone: minimum diameter0.30.62.21.1-1.51.1-0.4-0.1-0.41.40.30.41.3-0.40.81.0-0.70.5-1.0-0.10.4-0.3-1.3-0.0-0.7-0.7-0.0
Time in familiar zone, hab. session 10.30.31.7-0.50.9-0.4-0.30.5-0.2-0.80.50.3-0.70.3-0.5-0.50.4-0.30.5-0.10.1-0.11.30.50.90.90.3
Time in novel zone, hab. session 10.20.30.70.1-0.40.20.5-0.70.20.8-0.5-0.30.60.40.90.7-0.8-0.5-0.8-0.40.2-0.2-0.7-0.1-0.3-0.40.1
Total zone transitions, hab. session 10.20.20.70.8-0.70.6-0.80.6-0.50.30.70.60.4-0.8-0.3-0.10.30.60.10.3-0.00.1-0.40.0-0.4-0.2-0.0
Total locomotion distance, hab. session 10.40.51.70.7-0.90.5-0.90.8-0.5-0.00.60.40.1-1.2-0.8-0.50.81.30.60.9-0.60.6-0.8-0.4-0.8-0.7-0.7
Locomotion velocity, hab. session 10.10.20.80.6-0.60.5-0.70.6-0.60.10.50.50.2-0.7-0.4-0.20.40.90.20.4-0.20.3-0.4-0.1-0.4-0.3-0.2
Time in familiar zone, hab. session 20.50.61.6-1.01.3-1.10.9-1.11.0-1.0-1.0-0.9-0.90.5-0.5-0.60.40.20.5-0.4-0.10.00.9-0.10.50.50.7
Time in novel zone, hab. session 20.20.31.60.1-0.20.4-0.10.4-0.50.60.40.40.50.50.80.7-0.8-1.3-0.6-0.20.4-0.40.00.40.30.2-0.1
Total zone transitions, hab. session 20.71.02.20.0-0.3-0.4-0.1-0.40.7-0.9-0.5-0.7-0.7-1.3-1.5-1.31.51.51.21.0-1.01.0-1.0-1.2-1.2-1.2-0.8
Total locomotion distance, hab. session 21.72.25.30.6-1.00.0-0.90.50.2-1.00.0-0.3-0.7-2.3-2.2-1.72.22.31.71.9-1.61.7-1.6-1.6-1.9-1.8-1.6
Locomotion velocity, hab. session 21.62.26.01.0-1.30.4-1.20.9-0.2-0.60.40.1-0.4-2.4-2.0-1.52.02.41.51.9-1.41.5-1.7-1.4-1.9-1.7-1.6
Novel to familiar place preference ratio0.20.31.00.4-0.20.5-0.40.5-0.60.50.60.60.50.20.50.6-0.5-1.0-0.5-0.30.6-0.60.40.70.50.60.3
Novelty place preference0.40.61.90.4-0.10.5-0.30.4-0.70.80.60.70.70.50.90.9-0.9-1.4-0.9-0.70.9-0.90.70.90.80.90.7
Time in novel zone, NPP test0.70.82.80.3-0.00.5-0.20.3-0.70.90.60.70.80.81.11.1-1.1-1.7-1.1-0.91.1-1.10.81.11.01.10.9
Total zone transitions, NPP test1.01.54.11.3-1.51.0-1.81.4-0.9-0.01.20.80.1-2.0-1.3-0.81.31.41.01.5-0.91.0-1.4-0.8-1.5-1.3-1.4
Total locomotion distance, NPP test2.43.37.10.9-1.50.6-1.61.3-0.3-0.90.80.2-0.7-2.6-2.2-1.82.32.22.02.7-2.02.2-2.2-1.7-2.3-2.2-2.6
Locomotion velocity, NPP test3.14.49.81.2-1.80.7-1.91.6-0.4-0.91.00.3-0.7-3.1-2.6-2.12.62.72.23.0-2.32.4-2.5-1.9-2.7-2.5-2.9
Intraocular pressure0.30.51.2-0.60.5-0.70.00.50.7-1.1-0.3-0.6-1.0-0.4-1.1-1.11.00.91.10.6-0.90.8-0.0-0.6-0.4-0.3-0.8
Delta distance traveled before/after self-admin3.03.37.5-0.81.3-0.31.2-1.1-0.41.0-0.30.30.82.72.42.0-2.4-2.7-2.0-2.22.1-2.22.11.92.42.32.3
Delta ambulatory time before/after self-admin1.72.96.4-0.61.1-0.21.2-1.1-0.41.0-0.40.30.92.42.21.9-2.2-2.5-2.0-2.02.1-2.21.91.82.22.12.2
Parametrial fat weight2.76.511.3-2.51.8-3.02.3-2.13.2-3.2-3.0-3.4-3.2-0.6-2.8-3.12.81.53.01.4-2.82.6-1.1-3.0-1.9-2.1-1.7
Pavlov. Cond. lever latency4.45.512.9-3.53.2-3.63.4-3.13.5-3.0-3.5-3.5-3.11.4-1.3-2.11.30.11.9-0.1-1.41.20.8-1.70.1-0.3-0.0
Pavlov. Cond. magazine entry latency3.54.57.82.3-1.52.4-1.91.6-2.72.72.42.72.80.22.12.6-2.2-1.5-2.5-1.52.5-2.31.02.41.41.71.6
Pavlov. Cond. change in total contacts2.32.44.31.6-1.11.7-1.10.8-2.02.01.61.92.10.31.72.0-1.7-1.1-2.0-1.21.8-1.70.71.81.11.31.3
Pavlov. Cond. index score3.84.910.23.1-2.73.2-2.82.4-3.23.03.03.23.1-0.91.62.3-1.6-0.5-2.2-0.51.9-1.7-0.12.00.50.80.6
Pavlov. Cond. latency score4.15.210.93.2-2.83.3-2.92.5-3.33.13.13.33.2-1.01.72.4-1.7-0.5-2.3-0.52.0-1.8-0.22.00.40.80.7
Pavlov. Cond. lever contacts3.44.110.43.2-3.23.1-3.02.6-2.92.42.92.82.5-1.90.71.4-0.60.6-1.20.70.7-0.5-1.40.8-0.8-0.5-0.6
Pavlov. Cond. magazine entry number2.32.95.2-1.91.3-2.11.6-1.32.3-2.2-2.0-2.3-2.3-0.1-1.7-2.01.71.12.01.1-1.91.8-0.7-1.9-1.1-1.3-1.2
Pavlov. Cond. intertrial magazine entries1.72.04.3-1.30.9-1.40.6-0.41.2-2.1-1.0-1.4-2.0-0.5-1.8-2.01.81.02.01.3-1.81.8-0.4-1.5-0.9-1.1-1.4
Pavlov. Cond. lever-magazine prob. diff.3.74.610.03.1-2.63.1-2.72.4-3.22.83.03.13.0-0.91.52.2-1.5-0.4-2.1-0.41.8-1.6-0.11.90.40.80.6
Pavlov. Cond. response bias2.73.47.42.6-2.22.6-2.31.9-2.72.52.52.62.6-0.71.41.9-1.4-0.5-1.8-0.41.6-1.4-0.11.60.40.70.5
Pavlov. Cond. lever latency0.30.51.70.4-0.70.1-0.1-0.00.40.0-0.3-0.40.0-0.9-0.6-0.40.61.00.40.8-0.70.7-1.3-0.9-1.2-1.1-0.9
Pavlov. Cond. magazine entry latency0.30.41.00.8-0.91.0-0.90.9-0.70.91.00.90.8-0.10.60.7-0.5-0.3-0.6-0.10.4-0.3-0.20.50.10.10.1
Pavlov. Cond. change in total contacts0.51.22.5-0.20.60.20.10.1-0.50.60.50.70.51.41.41.1-1.4-1.5-1.1-1.41.2-1.21.41.41.61.51.4
Pavlov. Cond. index score0.40.61.10.2-0.00.6-0.40.4-0.70.70.80.80.60.71.00.9-1.0-1.0-0.9-0.80.9-0.90.81.11.01.00.9
Pavlov. Cond. latency score0.30.51.00.00.10.3-0.20.2-0.50.60.60.70.50.80.90.8-1.0-1.0-0.8-0.90.8-0.80.91.01.01.00.9
Pavlov. Cond. lever contacts0.20.41.3-0.40.7-0.20.2-0.1-0.2-0.10.20.3-0.10.80.50.3-0.5-0.9-0.3-0.80.5-0.61.10.81.01.00.8
Pavlov. Cond. magazine entry number0.00.00.2-0.20.4-0.30.4-0.30.2-0.2-0.4-0.3-0.10.2-0.0-0.0-0.0-0.1-0.0-0.30.1-0.10.2-0.00.20.10.3
Pavlov. Cond. intertrial magazine entries0.40.81.71.2-0.81.1-0.80.4-1.31.20.91.11.3-0.20.71.0-0.7-0.1-1.0-0.71.0-0.90.20.90.40.60.8
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.2-0.00.4-0.30.4-0.50.60.70.70.50.60.80.8-0.8-0.8-0.7-0.70.7-0.70.70.90.80.80.7
Pavlov. Cond. response bias0.30.40.80.3-0.20.5-0.50.5-0.70.50.80.80.50.40.60.6-0.6-0.6-0.6-0.50.7-0.70.70.90.80.80.6
Time in closed arm before self-admin0.20.30.90.2-0.00.4-0.30.2-0.50.70.30.40.60.40.80.7-0.8-0.5-0.7-0.40.9-1.00.20.50.30.30.4
Time in closed arm after self-admin0.10.10.30.0-0.20.1-0.30.20.0-0.00.1-0.1-0.1-0.2-0.1-0.20.20.10.20.3-0.50.5-0.5-0.4-0.5-0.5-0.3
Time in open arm before self-admin1.11.42.20.9-0.51.1-0.81.1-1.41.31.31.51.30.41.21.4-1.2-1.2-1.3-1.31.1-1.01.01.51.11.21.0
Time in open arm after self-admin0.70.81.50.2-0.00.6-0.30.5-0.90.80.80.90.70.91.21.1-1.2-0.8-1.0-1.11.0-1.00.91.21.11.10.9
Bone: periosteal estimation0.40.92.90.0-0.30.30.8-1.00.41.3-0.5-0.21.01.21.71.5-1.6-0.6-1.5-1.40.7-0.7-0.20.40.30.21.2
Bone: periosteal perimeter0.40.72.00.8-0.70.8-0.1-0.3-0.41.40.20.51.30.31.21.3-1.2-0.4-1.4-0.81.0-1.0-0.20.60.20.20.7
Bone: post-yield work0.40.83.31.0-1.61.0-0.80.3-0.20.90.60.40.7-0.90.00.20.01.0-0.20.7-0.60.6-1.8-0.6-1.3-1.3-0.8
Progressive ratio test 1 active lever presses0.10.20.60.3-0.60.5-0.70.6-0.60.30.80.60.2-0.00.30.2-0.2-0.1-0.10.4-0.50.6-0.20.2-0.0-0.0-0.5
Progressive ratio test 1 breakpoint0.10.20.60.3-0.60.6-0.70.6-0.60.30.80.60.30.00.30.3-0.3-0.2-0.20.3-0.50.5-0.20.2-0.0-0.0-0.4
Progressive ratio test 1 inactive lever presses0.41.12.2-0.60.1-0.80.2-0.50.9-1.3-0.5-0.9-1.3-0.8-1.4-1.51.41.11.51.3-1.41.4-0.8-1.2-1.0-1.1-1.1
Progressive ratio test 2 active lever presses0.10.10.40.3-0.40.3-0.60.3-0.4-0.10.60.5-0.1-0.4-0.4-0.30.30.20.30.4-0.10.20.10.1-0.00.0-0.2
Progressive ratio test 2 breakpoint0.10.10.40.2-0.30.2-0.60.3-0.4-0.10.60.5-0.0-0.3-0.3-0.20.30.00.20.3-0.10.10.30.20.10.2-0.0
Progressive ratio test 2 inactive lever presses0.20.72.11.1-1.41.3-1.20.9-1.20.91.41.20.8-0.60.30.4-0.3-0.1-0.30.7-0.10.2-0.80.2-0.5-0.4-0.6
Incentive Sensitization - Responses0.10.20.50.6-0.50.5-0.60.2-0.60.30.70.70.4-0.3-0.00.20.00.1-0.2-0.10.6-0.60.40.50.30.40.6
Incentive Sensitization - Breakpoint0.10.10.30.5-0.40.3-0.60.2-0.50.10.50.50.2-0.5-0.3-0.10.30.30.10.00.4-0.40.30.30.20.20.5
Sum of active levers in priming session hrs 5-60.80.71.40.7-0.71.0-0.60.8-1.21.11.11.11.00.41.11.1-1.0-0.4-1.0-0.40.9-0.90.10.90.50.60.3
Progressive ratio1.23.611.4-2.92.9-2.93.4-2.62.7-1.6-3.1-2.7-1.92.20.1-0.6-0.1-0.80.4-1.4-0.1-0.11.3-0.60.90.51.4
Food seeking constrained by brief footshock0.20.20.6-0.40.5-0.20.2-0.5-0.2-0.10.00.0-0.10.80.50.3-0.5-0.7-0.3-0.20.3-0.30.80.50.80.70.4
Seeking ratio, punishment vs. effort1.22.67.12.4-2.02.4-2.71.8-2.61.82.62.51.9-1.10.71.2-0.7-0.1-1.10.51.0-0.8-0.31.20.10.4-0.4
Retroperitoneal fat weight0.52.33.9-0.80.3-1.10.4-0.81.4-1.7-1.0-1.4-1.7-1.2-1.9-2.01.91.32.01.6-1.91.8-1.2-1.9-1.6-1.7-1.7
Reaction time number correct0.41.53.9-1.92.0-1.71.6-1.81.8-1.5-1.4-1.6-1.61.1-0.4-0.90.4-0.90.9-0.2-0.80.60.7-0.60.30.10.0
Reaction time mean minus median0.31.95.32.1-2.12.1-2.32.2-1.91.61.91.91.7-1.30.30.9-0.30.3-0.80.40.5-0.4-0.80.6-0.4-0.2-0.0
Reaction time mean minus median AUC0.42.47.12.3-2.42.4-2.72.7-2.11.62.42.21.7-1.60.20.8-0.20.4-0.60.80.10.1-1.10.6-0.7-0.4-0.6
Reaction time num false alarms0.30.51.10.8-0.60.60.00.3-0.61.00.30.61.10.10.80.9-0.8-0.1-1.0-0.70.7-0.70.30.80.50.60.9
Reaction time num false alarms AUC0.51.12.40.7-0.30.60.3-0.1-0.71.30.20.71.30.61.31.4-1.3-0.7-1.5-1.31.4-1.30.81.21.01.11.5
Reaction time trials correct on left0.41.53.9-1.92.0-1.71.6-1.81.8-1.5-1.4-1.6-1.61.1-0.4-0.90.4-0.90.9-0.2-0.80.60.7-0.60.30.10.0
Reaction time trials on left0.41.43.7-1.91.9-1.71.6-1.81.7-1.4-1.4-1.5-1.61.1-0.4-0.80.3-0.90.8-0.2-0.80.60.6-0.60.30.10.0
Reaction time mean1.22.67.42.4-2.72.1-2.32.3-1.51.31.71.51.4-2.3-0.40.20.51.3-0.11.7-0.50.7-2.2-0.4-1.7-1.4-1.5
Reaction time mean AUC1.02.46.92.3-2.62.0-2.22.1-1.51.21.71.51.3-2.2-0.40.20.51.2-0.11.7-0.50.7-2.0-0.3-1.6-1.3-1.5
Median of all reaction times1.32.15.41.9-2.31.6-1.81.8-1.00.81.21.00.9-2.1-0.7-0.20.71.50.31.9-0.91.0-2.2-0.7-1.8-1.6-1.8
Reaction time omissions0.91.44.71.7-2.21.5-1.81.2-1.11.01.21.21.0-1.7-0.30.10.41.6-0.10.8-0.40.6-1.6-0.3-1.2-1.0-0.8
Reaction time false alarm rate1.62.35.21.8-1.41.7-0.81.0-1.82.21.21.72.30.01.62.0-1.6-0.3-2.0-1.21.8-1.60.41.60.81.11.5
Reaction time premature initiation rate0.10.10.4-0.4-0.0-0.3-0.0-0.20.4-0.3-0.4-0.4-0.40.20.0-0.20.00.40.30.1-0.70.6-0.6-0.5-0.4-0.5-0.5
Reaction time premature initiations0.30.92.6-1.61.2-1.41.0-1.31.5-1.1-1.3-1.4-1.30.9-0.2-0.70.2-0.20.7-0.1-1.00.8-0.1-0.8-0.1-0.4-0.4
Std. dev. reaction times0.82.76.32.5-2.42.5-2.32.2-2.32.32.22.32.3-1.01.01.6-1.0-0.2-1.50.11.0-0.8-0.71.1-0.20.10.2
Reaction time trials completed0.41.43.7-1.91.9-1.71.6-1.81.7-1.4-1.4-1.5-1.61.1-0.4-0.80.3-0.90.8-0.2-0.80.60.6-0.60.30.10.0
Reaction time trials AUC0.41.43.4-1.81.8-1.71.5-1.81.8-1.5-1.4-1.6-1.60.9-0.6-1.00.6-0.71.0-0.1-0.90.70.5-0.80.1-0.1-0.1
Run reversals in cocaine runway, females0.50.52.0-0.70.7-0.70.50.20.7-0.9-0.3-0.6-1.00.0-0.6-0.80.60.10.90.8-1.41.4-0.1-0.6-0.3-0.4-0.8
Run reversals in cocaine runway, males0.60.62.21.1-1.21.2-1.51.1-1.11.01.11.11.0-0.40.40.6-0.4-0.1-0.6-0.20.6-0.5-0.60.4-0.2-0.10.1
Latency to leave start box in cocaine runway0.71.02.61.4-1.61.2-1.40.9-0.70.70.90.80.7-1.5-0.5-0.10.51.30.21.0-0.50.7-1.4-0.4-1.2-1.1-0.8
Latency to leave start box in cocaine runway, F0.81.02.91.2-1.41.1-1.31.0-0.70.51.00.80.6-1.4-0.5-0.20.51.70.20.8-1.11.2-1.2-0.3-1.0-0.9-0.7
Latency to leave start box in cocaine runway, M0.20.20.50.4-0.50.2-0.2-0.20.10.1-0.1-0.10.1-0.7-0.4-0.20.40.10.20.60.3-0.3-0.7-0.5-0.7-0.7-0.4
Std. dev. time between licks in bursts1.32.46.52.1-2.22.3-1.51.1-1.82.51.61.82.4-0.41.62.0-1.50.2-1.9-0.51.1-1.0-1.00.9-0.2-0.10.5
Total sessions with >9 infusions0.50.71.5-0.00.20.4-0.40.8-0.80.50.70.80.51.01.10.9-1.1-1.2-0.9-0.90.3-0.31.01.11.21.20.6
Short access day 1 total inactive lever presses0.40.92.31.1-1.21.5-1.10.8-1.41.21.51.31.1-0.20.90.9-0.9-0.7-0.80.1-0.40.5-0.80.5-0.2-0.2-0.4
Short access day 10 total inactive lever presses0.10.82.40.6-0.90.1-0.20.00.2-0.3-0.2-0.3-0.2-1.6-1.3-0.91.31.40.91.2-0.60.7-1.2-1.0-1.2-1.1-0.4
Short access day 1 total infusions0.40.82.70.7-0.71.1-1.21.7-1.30.91.41.30.90.31.00.9-1.0-1.1-0.8-0.2-0.00.10.10.90.50.5-0.1
Short access day 10 total infusions0.10.10.80.1-0.20.3-0.70.9-0.5-0.10.70.5-0.1-0.0-0.1-0.10.00.20.20.1-0.60.60.10.30.20.2-0.2
Short access total infusions0.30.41.70.3-0.40.7-0.91.3-0.90.41.11.00.40.20.60.5-0.6-0.6-0.30.0-0.40.50.10.60.40.4-0.3
Short access day 1 locomotion0.30.51.61.0-0.90.8-1.31.2-0.80.40.80.80.5-1.0-0.4-0.00.41.00.10.3-0.10.3-0.50.1-0.4-0.2-0.2
Short access day 10 total locomotion0.20.82.2-0.30.1-0.20.8-1.40.20.9-0.8-0.20.71.31.41.2-1.4-0.7-1.3-1.50.7-0.80.30.50.60.61.2
Short access total locomotion0.10.10.30.3-0.40.4-0.40.0-0.30.50.10.30.50.10.50.5-0.40.2-0.5-0.1-0.20.2-0.50.1-0.2-0.1-0.1
One hour access (0.3 mA shock)0.40.51.81.0-1.00.6-1.31.2-0.70.10.80.70.3-1.3-0.9-0.40.81.10.40.30.5-0.4-0.10.0-0.3-0.10.1
Compulsive drug intake1.31.97.41.8-2.20.9-1.21.1-0.20.40.20.20.6-2.7-1.6-0.81.62.60.71.1-0.20.4-2.0-1.2-2.1-1.8-0.5
One hour access (shock baseline)0.10.31.3-0.60.8-0.3-0.10.3-0.2-0.40.40.3-0.40.80.20.0-0.3-0.90.0-0.60.2-0.31.20.71.00.90.3
Social response proportion0.10.10.60.0-0.30.20.3-0.20.10.6-0.2-0.10.40.50.80.6-0.7-0.5-0.6-0.10.0-0.0-0.40.0-0.1-0.20.0
Social responses0.40.51.3-0.20.2-0.10.6-0.6-0.10.6-0.3-0.10.51.01.20.9-1.1-0.9-1.0-0.90.5-0.50.50.50.60.51.0
Social time0.71.14.21.8-2.01.4-1.40.9-1.01.30.80.91.4-1.5-0.10.50.11.4-0.50.40.10.0-1.4-0.1-1.0-0.80.1
Soleus weight0.72.17.32.2-2.72.1-1.10.8-1.12.50.91.02.3-1.01.31.6-1.10.6-1.60.20.3-0.1-2.2-0.0-1.3-1.1-0.4
Bone: stiffness0.81.53.2-1.31.0-1.51.3-1.71.8-1.5-1.6-1.7-1.5-0.1-1.2-1.41.21.01.30.4-1.31.2-0.3-1.3-0.7-0.8-0.5
Tibialis anterior weight0.20.81.9-1.21.1-1.41.2-0.90.8-1.4-1.2-1.1-1.30.3-0.8-1.00.80.41.0-0.1-0.80.70.5-0.60.1-0.00.1
Time to tail flick, vehicle, before self-admin1.01.34.4-0.00.2-0.80.4-0.51.1-1.2-1.1-1.0-0.8-1.5-1.9-1.51.92.11.31.50.1-0.1-0.4-1.2-1.0-0.9-0.7
Time to tail flick, vehicle, after self-admin0.20.51.01.0-0.80.9-0.60.8-0.80.90.81.01.0-0.30.50.7-0.50.2-0.7-0.50.7-0.70.00.60.20.30.2
Time to tail flick, test, before self-admin0.30.41.6-0.40.9-0.50.2-0.30.2-0.2-0.4-0.1-0.10.60.20.2-0.2-0.5-0.3-1.00.3-0.31.30.61.01.01.2
Time to tail flick, test, after self-admin0.60.62.11.0-0.61.0-1.01.4-1.40.61.41.30.7-0.40.10.4-0.2-0.1-0.3-0.30.6-0.50.60.90.50.70.5
Delta time to tail flick, vehicle, before/after SA0.80.82.60.7-0.61.2-1.01.4-1.40.81.61.40.80.30.90.9-0.9-1.0-0.7-0.60.00.10.31.00.60.7-0.1
Delta time to tail flick, test, before/after SA0.70.91.80.4-0.70.2-0.50.7-0.1-0.50.50.0-0.5-1.3-1.2-1.01.21.11.11.4-0.91.0-1.1-0.9-1.2-1.2-1.3
Tibia length0.20.62.1-0.1-0.40.11.0-1.40.61.1-0.8-0.60.70.91.41.1-1.3-0.0-1.1-0.6-0.30.2-1.1-0.2-0.4-0.50.2
Ambulatory time before self-admin0.10.41.80.1-0.5-0.1-0.50.30.3-0.4-0.1-0.3-0.4-0.8-0.8-0.70.81.30.70.3-0.80.8-0.8-0.8-0.9-0.9-0.5
Ambulatory time after self-admin0.40.61.7-0.60.6-0.50.7-0.90.20.3-0.7-0.40.11.21.00.7-1.0-0.8-0.7-1.30.9-1.00.50.40.70.61.2
Bone: tissue strength0.30.31.1-0.3-0.2-0.20.1-0.10.4-0.4-0.2-0.3-0.5-0.2-0.4-0.50.40.40.60.8-1.11.0-0.7-0.7-0.7-0.7-1.0
Total heroin consumption0.00.10.20.2-0.20.2-0.10.1-0.10.30.10.10.3-0.00.20.3-0.20.1-0.3-0.30.5-0.50.10.20.10.10.3
Bone: trabecular number1.12.14.90.3-0.5-0.0-1.21.80.0-1.40.70.2-1.1-1.9-2.2-1.92.21.72.01.9-1.71.8-0.8-1.1-1.2-1.1-1.7
Bone: trabecular spacing1.21.73.8-0.50.8-0.31.5-1.80.51.0-1.0-0.50.81.92.01.6-1.9-1.7-1.7-1.61.3-1.40.70.81.11.01.3
Bone: trabecular thickness1.41.94.5-0.1-0.4-0.4-0.60.90.3-1.50.1-0.3-1.3-1.7-2.1-1.92.11.72.01.7-1.81.8-0.9-1.4-1.4-1.3-1.6
Bone: trabecular tissue density1.42.46.50.10.40.60.0-0.3-0.81.40.71.01.21.82.01.9-2.0-2.6-1.9-2.01.7-1.81.61.91.91.91.9
Water consumed over 24 hours0.10.10.30.6-0.50.4-0.2-0.1-0.40.60.20.30.6-0.20.30.4-0.3-0.2-0.4-0.10.3-0.2-0.20.1-0.1-0.10.1
Number of responses in last shaping day1.92.56.01.0-1.01.4-0.60.9-1.52.21.01.52.01.22.52.4-2.4-1.6-2.4-1.61.4-1.30.41.71.11.11.3