Hub : Genes

Rnf5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Rnf5 0.15 0.06 5.4e-12 0.1 0.13 0.1 0.11 8.8e-09 1.2e-10 9.1e-09 3.1e-09
2 NAcc intron excision ratio chr20_4150384_4151388 0.03 0.02 1.0e-04 0.02 0.02 0.02 0.02 1.5e-03 6.9e-04 4.9e-04 6.6e-04
3 IC mRNA stability Rnf5 0.31 0.12 5.6e-11 0.18 0.23 0.22 0.21 6.2e-08 5.7e-10 7.9e-10 3.3e-09
4 PL intron excision ratio chr20_4150384_4151388 0.09 0.05 1.3e-09 0.1 0.05 0.07 0.09 1.6e-10 1.6e-06 5.2e-08 3.6e-10
5 LHb mRNA stability Rnf5 0.29 0.16 6.2e-04 0.14 0.14 0.1 0.15 3.8e-04 2.6e-04 2.2e-03 2.1e-04
6 OFC mRNA stability Rnf5 0.29 0.13 2.1e-04 0.12 0.14 0.12 0.14 7.8e-04 3.0e-04 8.0e-04 3.9e-04
7 Brain mRNA stability Rnf5 0.23 0.1 0.0e+00 0.18 0.17 0.16 0.18 1.5e-16 4.4e-16 4.1e-15 1.4e-16
8 BLA mRNA stability Rnf5 0.35 0.13 2.7e-13 0.21 0.22 0.21 0.21 2.2e-11 9.3e-12 2.0e-11 2.1e-11
9 PL mRNA stability Rnf5 0.21 0.08 0.0e+00 0.22 0.18 0.21 0.22 1.5e-23 2.4e-19 5.1e-23 3.1e-24
10 NAcc mRNA stability Rnf5 0.1 0.04 2.3e-14 0.1 0.1 0.1 0.1 1.9e-14 5.2e-15 7.5e-15 2.1e-14
11 IC gene expression Rnf5 0.16 0.09 5.0e-05 0.03 0.08 0.05 0.05 1.4e-02 3.3e-04 3.4e-03 3.7e-03
12 Brain intron excision ratio chr20_4151748_4151824 0.15 0.07 5.2e-08 0.04 0.08 0.04 0.05 1.7e-04 6.8e-08 5.9e-05 1.1e-05
13 pVTA intron excision ratio chr20_4151748_4151824 0.07 0.04 4.0e-04 0.01 0.04 0.04 0.04 2.8e-02 2.6e-04 3.7e-04 3.2e-04
14 Brain intron excision ratio chr20_4151612_4151694 0.13 0.06 3.3e-07 0.03 0.06 0.02 0.03 6.7e-04 1.4e-06 3.8e-03 3.6e-04
15 PL gene expression Rnf5 0.08 0.05 4.0e-07 0.03 0.05 0.06 0.05 2.3e-04 4.6e-06 1.2e-06 8.3e-06
16 pVTA intron excision ratio chr20_4151612_4151694 0.07 0.04 5.4e-04 0.02 0.04 0.04 0.03 1.8e-02 2.5e-04 7.3e-04 2.1e-03
17 PL intron excision ratio chr20_4151612_4151694 0.05 0.03 6.8e-04 0.03 0.03 0.02 0.03 3.3e-04 4.5e-04 9.7e-04 3.2e-04
18 NAcc intron excision ratio chr20_4151748_4151824 0.05 0.03 3.0e-05 0.02 0.03 0.03 0.04 1.9e-04 2.2e-05 7.0e-06 1.1e-06
19 NAcc intron excision ratio chr20_4151612_4151694 0.05 0.03 2.9e-05 0.02 0.03 0.03 0.04 1.9e-04 3.2e-05 2.7e-05 3.0e-06
20 NAcc gene expression Rnf5 0.2 0.09 0.0e+00 0.12 0.16 0.15 0.15 1.1e-17 9.2e-23 1.7e-21 4.5e-22
21 Adipose gene expression Rnf5 0.03 0.02 4.2e-03 0 0 -0 -0 2.6e-01 9.1e-02 9.3e-01 6.0e-01
22 BLA intron excision ratio chr20_4151748_4151824 0.09 0.06 6.4e-03 0.01 0.02 -0 0.02 8.7e-02 4.3e-02 6.4e-01 4.6e-02
23 pVTA gene expression Rnf5 0.16 0.07 1.9e-10 0.08 0.12 0.1 0.1 1.1e-06 4.2e-10 3.9e-08 1.9e-08
24 PL intron excision ratio chr20_4151748_4151824 0.05 0.04 1.1e-03 0.02 0.03 0.02 0.03 1.0e-03 5.9e-04 2.9e-03 5.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.91.53.50.30.60.01.11.5-1.10.20.60.2-0.9-1.7-1.9-1.61.8-1.41.71.5-1.51.5-0.7-0.9-1.1-1.0-1.3
Area under the delay curve0.50.61.6-0.1-0.50.0-0.5-0.60.60.0-0.20.10.61.01.01.0-1.01.3-1.0-0.70.9-0.90.90.91.01.00.6
BMI with tail1.86.211.6-2.7-2.0-3.1-2.4-2.8-3.1-3.3-3.1-3.4-3.2-0.2-2.4-2.92.4-1.82.81.2-2.52.3-0.9-2.9-1.6-2.0-1.4
BMI without tail1.13.210.0-2.9-2.7-2.6-2.8-3.2-1.4-2.6-2.6-2.3-1.82.50.5-0.4-0.51.00.3-1.4-0.40.11.1-0.50.90.51.0
Body weight1.14.718.6-3.0-2.3-3.0-3.6-4.3-1.7-3.5-3.8-3.5-2.11.8-0.0-0.90.10.00.8-0.3-1.51.2-0.5-1.9-0.5-1.0-0.2
Weight adjusted by age0.30.51.8-0.9-0.3-0.5-1.1-1.20.2-0.8-0.8-0.6-0.11.41.10.6-1.10.7-0.6-0.7-0.30.2-0.4-0.20.0-0.2-0.2
Bone surface0.10.10.40.40.60.40.40.50.3-0.00.30.20.2-0.4-0.10.00.1-0.40.00.1-0.30.3-0.6-0.2-0.4-0.4-0.0
Bone volume0.20.30.8-0.10.2-0.20.20.3-0.5-0.30.0-0.2-0.5-0.5-0.7-0.70.7-0.60.70.5-0.90.9-0.5-0.5-0.5-0.5-0.4
Breakpoint value in progressive ratio session0.20.20.70.60.70.60.80.80.50.40.60.50.5-0.30.10.3-0.1-0.3-0.3-0.3-0.20.30.00.30.10.10.4
Number of licking bursts0.60.92.41.61.51.41.00.41.51.11.01.21.5-0.60.71.1-0.70.2-1.1-0.20.8-0.7-0.50.6-0.10.00.4
Context. condit. distance diff. score3.84.612.13.23.52.93.32.91.72.52.82.41.8-2.9-0.50.30.6-2.2-0.11.9-0.50.7-2.4-0.2-1.9-1.6-1.7
Locomotion velocity, session 11.92.04.21.61.21.91.71.61.81.92.02.01.80.11.41.6-1.41.1-1.5-0.71.3-1.20.31.50.70.90.6
Locomotion distance, session 10.50.61.50.60.50.41.11.2-0.40.70.80.5-0.2-1.2-1.1-0.81.0-0.80.91.0-0.60.7-0.4-0.4-0.6-0.5-0.9
Locomotion velocity, session 20.30.41.01.00.80.90.80.70.80.90.80.80.9-0.50.30.6-0.30.1-0.6-0.10.6-0.50.00.50.10.20.2
Locomotion distance, session 21.01.44.21.01.10.51.20.9-0.40.60.60.3-0.2-2.0-1.5-1.11.5-1.61.21.8-1.11.2-1.2-1.0-1.5-1.3-1.7
Locomotion velocity, session 30.40.51.6-0.6-1.0-0.5-0.6-0.6-0.2-0.0-0.2-0.1-0.11.00.50.3-0.61.1-0.3-0.90.6-0.71.30.71.11.00.9
Locomotion distance, session 30.40.51.61.00.70.81.31.10.11.21.21.00.4-1.0-0.5-0.20.5-0.70.30.6-0.00.10.00.3-0.20.0-0.5
Stereotopy head waving bouts, day 30.50.61.40.1-0.10.2-0.6-0.71.0-0.2-0.4-0.10.80.81.21.1-1.21.1-1.2-0.80.8-0.80.20.50.50.40.8
Stereotopy head waving duration, day 31.11.33.7-0.2-0.50.1-0.7-0.71.1-0.0-0.20.10.81.61.81.5-1.81.9-1.5-1.51.2-1.30.71.01.11.01.3
Locomotion velocity, session 73.53.810.11.72.01.12.22.0-0.61.21.50.9-0.2-3.2-2.3-1.72.3-2.81.82.9-1.71.9-1.9-1.3-2.1-1.9-2.6
Locomotion distance, session 71.92.47.02.01.91.72.62.20.22.02.21.80.6-2.5-1.4-0.71.3-1.80.81.9-0.60.8-0.8-0.1-1.0-0.7-1.6
Stereotopy head waving bouts, day 73.13.58.0-0.0-0.80.4-0.5-0.31.40.70.40.81.32.12.32.1-2.32.8-2.2-2.52.4-2.42.22.22.42.42.4
Stereotopy head waving duration, day 71.72.05.1-0.4-1.0-0.1-0.9-0.60.80.1-0.20.20.71.81.71.5-1.72.3-1.6-2.01.8-1.91.71.51.81.81.9
Locomotion velocity, session 82.42.96.92.62.52.62.01.52.62.22.02.12.6-0.91.41.9-1.30.1-1.8-0.21.3-1.1-1.01.0-0.3-0.10.2
Locomotion distance, session 84.26.115.93.13.62.63.42.70.82.22.41.81.1-4.0-1.8-0.81.8-3.21.03.0-1.51.8-3.2-1.2-2.9-2.5-2.8
Degree of sensitization distance0.30.41.41.01.20.90.80.40.80.50.60.60.8-0.70.10.4-0.1-0.5-0.40.30.1-0.0-0.8-0.0-0.5-0.4-0.2
Degree of sensitization stereotypy2.22.34.40.3-0.50.60.10.31.21.10.81.11.21.41.71.7-1.82.1-1.7-1.92.0-2.01.92.02.02.02.0
Conditioned locomotion0.50.61.3-0.30.2-0.5-0.6-0.8-0.4-1.0-0.9-0.9-0.5-0.4-0.6-0.60.7-1.00.60.9-0.90.9-1.1-1.1-1.1-1.1-0.9
Cocaine response after cond. corrected2.42.95.90.51.2-0.20.50.2-1.0-0.6-0.4-0.8-0.8-2.3-2.2-1.82.2-2.41.82.2-1.81.9-2.1-2.0-2.3-2.2-2.2
Cocaine response after cond. not corrected0.30.31.10.40.80.1-0.1-0.30.1-0.4-0.5-0.40.1-0.8-0.4-0.20.4-0.80.20.5-0.30.4-1.1-0.8-1.0-0.9-0.6
Cocaine response before conditioning4.45.311.0-0.7-1.3-0.1-1.6-1.41.70.0-0.50.21.43.33.32.8-3.33.0-2.9-3.32.6-2.82.22.22.62.53.0
Saline control response3.14.111.4-3.0-3.4-2.6-3.0-2.5-1.4-2.1-2.3-1.8-1.63.10.80.0-0.92.3-0.1-2.10.7-1.02.40.42.11.71.7
Bone: connectivity density1.52.34.40.40.90.11.11.6-1.10.00.4-0.1-0.9-2.1-2.1-1.82.1-2.01.92.0-1.81.9-1.6-1.5-1.8-1.7-1.8
Bone: cortical apparent density1.52.14.8-2.0-1.9-2.2-2.0-1.7-2.0-2.1-2.1-2.0-2.00.6-1.1-1.51.1-0.11.40.3-0.90.70.5-1.1-0.1-0.2-0.4
Bone: cortical area0.10.10.3-0.1-0.2-0.2-0.5-0.60.2-0.4-0.5-0.20.20.40.40.3-0.40.3-0.4-0.50.5-0.50.20.20.30.30.5
Bone: cortical porosity5.96.414.90.5-0.61.20.20.32.21.71.41.92.12.63.33.1-3.33.9-3.1-2.92.9-3.02.73.23.23.22.7
Bone: cortical porosity5.76.213.90.9-0.11.60.60.52.51.91.72.12.42.33.33.2-3.33.7-3.1-2.62.8-2.92.23.12.82.82.5
Bone: cortical thickness0.71.23.5-1.6-1.9-1.7-1.5-1.4-1.5-1.4-1.6-1.4-1.40.8-0.7-0.90.60.30.8-0.3-0.10.01.1-0.30.60.50.3
Bone: cortical thickness2.12.46.0-2.2-2.4-2.4-2.1-2.2-2.2-1.9-2.2-2.1-2.10.8-1.1-1.51.00.11.3-0.2-0.80.71.1-0.90.30.20.1
Bone: cortical tissue density1.41.94.4-1.9-1.8-2.1-1.9-1.6-1.9-2.0-2.0-1.9-1.90.6-1.0-1.41.0-0.01.30.3-0.80.70.5-1.0-0.0-0.2-0.4
Condit. Reinf. active minus inactive responses1.01.22.20.70.20.90.70.80.91.41.11.31.10.51.11.1-1.11.3-1.1-0.81.2-1.21.21.51.21.30.9
Condit. Reinf. active-inactive response ratio0.70.72.1-0.7-1.1-0.5-0.8-0.5-0.1-0.1-0.3-0.1-0.01.20.70.5-0.81.3-0.6-1.10.8-0.91.50.81.31.21.1
Condit. Reinf. active responses0.20.20.90.50.30.50.70.70.11.00.80.80.3-0.3-0.00.1-0.00.0-0.10.20.2-0.10.50.50.30.4-0.0
Condit. Reinf. inactive responses0.81.02.50.40.50.11.00.9-0.90.40.60.3-0.6-1.5-1.6-1.31.5-1.61.41.4-1.01.1-0.5-0.7-0.8-0.7-1.2
Incentive salience index mean1.11.43.61.91.71.71.81.81.21.81.71.71.4-1.30.10.6-0.1-0.4-0.60.50.4-0.3-0.40.6-0.3-0.0-0.4
Condit. Reinf. lever presses2.94.110.22.73.22.22.82.61.01.82.01.61.2-3.2-1.2-0.41.3-2.70.52.2-0.91.2-2.5-0.8-2.3-1.9-2.1
Condit. Reinf. active minus inactive responses0.91.22.8-0.4-0.60.0-0.7-0.60.80.1-0.10.20.61.61.71.3-1.71.4-1.4-1.51.1-1.11.01.11.31.21.4
Condit. Reinf. active-inactive response ratio1.11.33.70.1-0.00.5-0.4-0.31.30.40.20.51.11.51.91.7-1.91.4-1.7-1.51.2-1.20.61.11.00.91.3
Condit. Reinf. active responses0.40.51.2-0.3-0.50.0-0.3-0.20.50.20.10.20.31.11.10.8-1.10.9-0.8-1.10.7-0.70.80.81.00.91.0
Condit. Reinf. inactive responses0.20.30.8-0.8-0.9-0.8-0.6-0.7-0.8-0.6-0.6-0.7-0.80.2-0.5-0.60.4-0.00.5-0.1-0.20.20.5-0.20.20.20.2
Condit. Reinf. lever presses0.71.01.70.50.20.90.60.60.91.21.21.30.90.71.21.1-1.20.9-1.0-1.01.0-1.00.91.31.11.11.0
Condit. Reinf. lever reinforcers received0.60.91.8-0.0-0.30.3-0.1-0.00.80.50.40.60.71.21.31.2-1.31.1-1.1-1.31.0-1.01.01.21.21.11.3
Conditioned reinforcement - actives0.10.10.6-0.3-0.0-0.20.1-0.2-0.4-0.20.1-0.2-0.50.0-0.2-0.40.2-0.40.40.3-0.70.7-0.0-0.2-0.1-0.2-0.4
Conditioned reinforcement - inactives0.00.10.3-0.3-0.1-0.0-0.1-0.1-0.1-0.00.30.1-0.20.50.30.1-0.30.50.0-0.1-0.30.30.20.20.20.1-0.1
Conditioned locomotion0.10.10.50.20.50.40.70.50.20.40.50.40.2-0.00.20.2-0.2-0.1-0.10.3-0.30.3-0.30.1-0.2-0.1-0.6
Patch foraging indifference point 0 sec1.22.25.6-2.4-2.3-2.1-2.1-2.3-1.3-1.8-1.9-1.6-1.42.20.4-0.2-0.51.30.1-1.3-0.1-0.11.60.11.31.00.8
Patch foraging indifference point AUC1.01.53.80.0-0.40.20.0-0.10.90.40.10.50.91.31.41.4-1.41.6-1.4-1.81.9-2.01.41.41.51.51.6
Delay disc. indifference point, 0s delay0.20.20.60.70.80.60.20.20.50.20.30.30.6-0.50.10.2-0.00.2-0.30.4-0.30.4-0.6-0.1-0.5-0.4-0.4
Delay disc. indifference point, 16s delay0.40.41.3-0.7-1.1-0.6-0.7-0.6-0.3-0.2-0.4-0.2-0.20.90.40.2-0.40.9-0.3-0.50.7-0.71.10.50.90.90.4
Delay disc. indifference point, 2s delay1.21.43.70.50.40.90.10.11.60.70.50.91.41.11.91.8-1.91.4-1.8-0.91.1-1.00.61.31.11.10.8
Delay disc. indifference point, 24s delay1.71.94.3-0.5-1.0-0.1-0.8-0.90.70.3-0.10.40.72.01.81.5-1.82.1-1.6-1.21.8-1.91.71.51.91.91.0
Delay disc. indifference point, 4s delay1.01.02.3-0.5-0.8-0.3-1.0-1.10.6-0.5-0.7-0.20.51.51.41.1-1.41.5-1.2-1.30.6-0.61.00.91.21.11.2
Delay disc. indifference point, 8s delay0.30.31.00.1-0.40.1-0.3-0.20.40.1-0.10.20.50.50.60.6-0.61.0-0.7-0.50.8-0.80.70.70.70.80.3
Indifference point function ln k0.30.61.41.10.81.10.50.61.11.00.91.01.2-0.20.70.9-0.70.2-0.9-0.20.5-0.4-0.00.70.20.30.5
Indifference point function log k0.30.61.41.10.81.10.50.61.11.00.91.01.2-0.20.70.9-0.70.2-0.9-0.20.5-0.4-0.00.70.20.30.5
Patch foraging total patch changes 0 sec1.32.46.0-2.4-2.4-2.2-2.2-2.4-1.3-1.9-2.0-1.6-1.52.20.4-0.3-0.51.40.1-1.3-0.0-0.11.70.11.41.10.8
Patch foraging total patch changes 12 sec1.21.63.8-1.9-2.0-1.7-1.5-1.5-0.8-1.3-1.5-1.2-1.01.90.50.0-0.51.2-0.1-1.60.6-0.81.60.41.41.21.2
Patch foraging total patch changes 18 sec2.03.17.3-2.5-2.4-2.7-1.9-2.1-2.6-2.4-2.3-2.3-2.60.7-1.6-2.01.5-0.21.8-0.2-1.00.90.9-1.30.1-0.1-0.2
Patch foraging total patch changes 24 sec0.50.93.0-1.4-1.5-1.5-0.5-0.4-1.7-0.9-0.9-1.0-1.60.3-1.1-1.31.00.11.30.2-0.60.50.9-0.50.30.2-0.5
Patch foraging total patch changes 6 sec1.21.84.9-2.2-2.2-2.0-1.9-1.6-1.4-1.6-1.7-1.4-1.41.90.2-0.4-0.21.40.3-1.20.0-0.21.60.01.20.90.6
Patch foraging time to switch 0 sec2.55.28.9-1.2-0.5-1.7-1.1-0.8-2.5-2.0-1.6-2.2-2.4-1.6-2.8-2.92.8-2.62.92.5-3.02.9-1.9-2.8-2.4-2.5-2.4
Patch foraging water rate 0 sec0.10.20.7-0.4-0.3-0.3-0.5-0.70.1-0.3-0.5-0.3-0.00.60.40.3-0.40.8-0.3-0.40.3-0.30.40.10.30.30.1
Patch foraging water rate 12 sec0.10.20.6-0.5-0.5-0.6-0.2-0.4-0.8-0.4-0.4-0.4-0.7-0.0-0.6-0.60.60.10.60.1-0.10.00.5-0.20.20.2-0.0
Patch foraging water rate 18 sec0.20.30.9-0.8-0.6-0.8-0.8-1.0-0.6-0.7-0.8-0.8-0.60.6-0.1-0.30.10.60.2-0.00.2-0.20.5-0.20.30.2-0.1
Patch foraging water rate 24 sec0.20.31.0-0.7-0.7-0.7-0.6-1.0-0.6-0.7-0.6-0.7-0.70.3-0.3-0.40.30.00.4-0.4-0.40.30.3-0.20.20.10.5
Patch foraging water rate 6 sec0.20.30.6-0.6-0.5-0.8-0.5-0.5-0.8-0.7-0.7-0.8-0.70.0-0.6-0.60.60.00.60.2-0.10.10.3-0.4-0.0-0.1-0.2
Seeking ratio, delayed vs. immediate footshock2.02.57.7-1.1-1.7-1.1-1.5-0.90.2-1.0-1.3-0.60.12.11.31.0-1.41.2-1.2-2.81.8-1.92.21.22.01.92.7
Distance traveled before self-admin0.91.23.7-0.10.6-0.40.1-0.2-0.7-0.9-0.7-0.9-0.7-1.1-1.2-1.11.3-1.91.10.6-1.51.5-1.5-1.5-1.6-1.6-0.8
Distance traveled after self-admin0.50.61.9-0.9-0.7-0.9-1.1-1.4-0.0-0.9-1.2-0.9-0.21.10.60.3-0.60.4-0.4-1.20.7-0.80.4-0.00.40.31.2
Extensor digitorum longus weight0.10.41.50.71.20.70.60.50.70.30.50.40.5-0.60.10.2-0.1-0.9-0.20.3-0.40.4-1.2-0.3-0.9-0.8-0.4
Bone: elastic displacement0.50.62.7-0.4-0.7-0.2-0.30.20.00.30.20.30.01.10.70.5-0.81.6-0.5-0.70.7-0.81.30.91.21.20.5
Bone: elastic work0.10.20.7-0.5-0.5-0.4-0.5-0.1-0.1-0.3-0.3-0.2-0.10.70.40.2-0.40.8-0.3-0.40.2-0.30.60.30.50.50.2
Bone: endosteal estimation0.71.55.10.61.00.9-0.4-0.82.1-0.1-0.10.21.61.22.32.1-2.10.7-2.1-1.50.6-0.7-0.80.60.1-0.01.2
Bone: endosteal perimeter0.61.34.31.72.11.60.90.42.00.70.80.81.8-0.51.11.4-1.0-0.5-1.4-0.30.6-0.5-1.50.2-0.8-0.70.2
Epididymis fat weight5.920.242.9-5.6-4.7-6.0-4.1-4.3-6.5-5.6-5.1-5.9-6.50.2-4.7-5.74.6-2.45.52.4-4.44.00.0-4.3-1.6-2.2-2.4
Delta time in closed arm before/after self-admin0.50.41.3-0.30.3-0.2-0.2-0.3-0.3-0.6-0.4-0.6-0.5-0.3-0.4-0.50.5-0.40.60.7-1.21.1-1.1-0.9-0.9-1.0-0.9
Delta time in open arm before/after self-admin0.10.10.3-0.4-0.6-0.2-0.2-0.2-0.20.00.00.0-0.20.60.30.1-0.30.2-0.0-0.20.2-0.30.50.30.60.50.3
Diff in mean of infusions in LGA sessions1.51.85.91.31.40.71.31.4-0.30.60.80.40.0-2.4-1.8-1.21.8-2.11.21.8-0.91.1-1.3-1.0-1.6-1.3-1.3
Delay discount exponential model param0.80.92.30.10.6-0.10.50.6-0.7-0.10.2-0.3-0.7-1.2-1.3-1.21.3-1.51.31.0-1.11.1-1.1-1.1-1.3-1.3-0.8
Extinction: sum of active levers before priming0.50.51.81.11.31.01.30.90.80.80.80.70.8-0.80.10.3-0.1-0.7-0.30.70.4-0.4-0.70.0-0.6-0.5-0.6
Active lever presses in extinction session 60.10.10.5-0.20.10.00.40.4-0.40.10.4-0.0-0.4-0.2-0.3-0.40.3-0.10.50.3-0.50.5-0.1-0.2-0.2-0.3-0.7
Bone: final force1.62.56.2-2.0-1.6-2.2-2.2-2.5-1.8-2.4-2.5-2.4-1.90.5-1.0-1.41.0-0.71.30.2-1.41.3-0.2-1.5-0.6-0.8-0.4
Bone: final moment1.11.84.6-1.8-1.4-1.9-1.9-2.1-1.5-2.0-2.0-2.0-1.60.6-0.7-1.10.7-0.41.00.1-1.21.1-0.1-1.2-0.4-0.6-0.3
Food consumed during 24 hour testing period0.81.12.6-0.10.5-0.4-0.4-0.8-0.5-0.9-0.9-0.9-0.5-0.9-0.9-0.91.0-1.50.81.1-1.21.2-1.6-1.5-1.5-1.6-1.2
Glucose3.04.711.53.23.33.42.51.93.32.72.72.73.2-1.01.92.4-1.80.2-2.3-0.01.2-1.0-1.51.2-0.5-0.3-0.1
Heart weight1.62.47.4-0.7-1.0-0.1-1.3-1.31.1-0.1-0.40.00.82.52.41.9-2.42.7-1.9-1.91.4-1.61.21.41.71.51.6
Delay discount hyperbolic model param1.11.22.70.00.6-0.10.50.6-0.9-0.20.1-0.4-0.9-1.4-1.5-1.41.5-1.71.51.2-1.11.1-1.2-1.3-1.4-1.4-1.1
Intermittent access intake day 1-15 change0.20.41.2-0.2-0.6-0.3-0.5-0.60.1-0.1-0.30.00.20.60.40.4-0.40.8-0.5-0.61.1-1.10.90.50.80.81.0
Intermittent access intake escalation0.51.13.1-0.9-1.5-0.9-1.0-0.9-0.3-0.4-0.7-0.3-0.21.30.50.4-0.61.5-0.5-1.21.2-1.31.80.81.41.41.5
Intermittent access intake escalation 20.50.62.00.3-0.10.30.0-0.40.60.50.30.50.60.50.70.8-0.81.3-0.8-0.61.4-1.40.90.90.80.91.0
Intermitt. access day 1 inactive lever presses0.20.73.11.11.71.00.60.00.80.30.40.40.7-1.2-0.10.10.2-0.8-0.10.8-0.40.5-1.8-0.6-1.3-1.3-0.5
Intermitt. access day 15 inactive lever presses0.00.10.2-0.3-0.1-0.2-0.4-0.40.0-0.4-0.3-0.3-0.10.40.30.1-0.20.2-0.1-0.10.1-0.1-0.2-0.2-0.1-0.20.0
Intermitt. access escalation Index1.01.55.11.51.60.91.31.70.20.70.80.60.4-2.2-1.3-0.71.3-2.30.71.3-0.81.0-1.3-0.7-1.4-1.2-0.8
Intermittent access day 1 total infusions0.50.93.71.01.21.31.81.90.51.51.81.40.5-0.70.00.10.0-0.30.00.5-0.70.8-0.30.4-0.1-0.1-0.7
Intermittent access day 15 total infusions0.20.31.1-0.2-0.50.00.20.5-0.00.40.50.5-0.00.60.30.3-0.40.9-0.2-0.50.2-0.21.10.80.90.90.6
Intermittent access terminal intake (last 3 days)0.40.61.8-0.2-0.50.20.30.30.30.60.70.70.21.00.90.7-0.91.3-0.6-0.80.5-0.51.21.01.21.10.7
Intermittent access total infusions0.30.30.90.10.00.40.60.80.20.71.00.80.20.50.60.4-0.60.8-0.3-0.4-0.00.00.60.80.70.70.2
Intermittent access day 1 locomotion0.30.41.9-0.10.2-0.10.50.5-0.5-0.00.3-0.0-0.5-0.4-0.6-0.60.6-0.70.70.7-1.41.4-0.4-0.4-0.4-0.4-0.8
Intermittent access day 15 total locomotion0.20.41.0-0.9-0.9-0.9-0.9-1.0-0.6-1.0-1.0-0.8-0.60.70.0-0.2-0.00.10.1-0.30.0-0.10.4-0.20.20.20.1
Intermittent access total locomotion0.20.20.6-0.8-0.7-0.6-0.5-0.7-0.6-0.5-0.4-0.4-0.60.60.0-0.2-0.00.10.2-0.2-0.30.20.50.00.40.3-0.0
Intermittent access standard deviation0.71.54.3-2.0-1.8-1.8-1.8-2.1-1.1-1.8-1.7-1.5-1.31.60.2-0.4-0.21.40.3-0.90.0-0.20.8-0.30.70.40.5
Left kidney weight1.15.218.6-3.4-3.1-3.3-4.1-4.3-1.9-3.4-3.7-3.4-2.22.50.2-0.8-0.20.80.6-0.9-1.00.70.6-1.20.4-0.10.5
Right kidney weight1.15.216.7-3.3-2.7-3.2-3.9-4.1-2.1-3.7-3.7-3.6-2.51.8-0.4-1.30.5-0.11.1-0.2-1.51.3-0.3-1.9-0.4-0.8-0.1
Cocaine induced anxiety0.30.41.50.50.70.20.3-0.0-0.0-0.3-0.1-0.20.0-1.1-0.7-0.50.7-1.20.50.4-0.70.8-1.0-0.7-1.0-1.0-0.4
Post-drug Anxiety0.10.10.6-0.10.0-0.2-0.4-0.5-0.1-0.7-0.4-0.4-0.1-0.2-0.2-0.20.2-0.70.20.2-0.40.4-0.5-0.5-0.5-0.5-0.0
Baseline Anxiety0.20.21.1-0.4-0.5-0.3-0.6-0.40.0-0.3-0.3-0.2-0.00.70.50.3-0.50.3-0.3-0.01.0-1.10.40.20.50.40.2
Tail length1.66.317.0-0.4-0.60.3-1.6-2.12.5-0.1-0.60.42.03.54.13.5-4.03.3-3.6-3.32.2-2.41.62.32.52.32.8
Length with tail0.73.09.1-0.8-0.5-0.3-2.1-2.71.6-0.9-1.5-0.71.12.83.02.4-2.92.0-2.5-2.00.9-1.10.20.81.10.91.5
Length without tail1.03.38.4-1.4-0.2-1.6-2.2-2.9-1.0-2.5-2.7-2.7-1.3-0.0-0.6-1.10.8-1.41.01.0-2.12.0-2.4-2.4-2.0-2.3-1.5
Times rat made contact with spout0.80.94.5-0.6-1.3-0.6-0.4-0.1-0.50.3-0.10.1-0.30.90.20.1-0.31.7-0.2-1.00.9-0.92.11.11.61.61.2
Lifetime Intake0.20.30.70.00.00.40.50.80.20.60.80.70.20.50.50.4-0.50.7-0.3-0.3-0.20.20.50.70.60.60.1
Liver weight, left0.20.41.50.50.90.5-0.2-1.21.0-0.2-0.4-0.20.8-0.10.70.7-0.6-0.4-0.7-0.2-0.30.3-1.2-0.4-0.8-0.80.0
Liver weight, right0.40.82.91.11.31.10.3-0.21.70.50.30.41.50.01.31.3-1.2-0.2-1.3-0.30.00.1-1.10.2-0.5-0.40.2
Locomotor activity1.21.94.5-0.2-0.60.0-0.7-1.01.20.0-0.40.31.01.92.01.8-2.01.1-1.9-2.11.5-1.61.21.41.61.51.9
Locomotor testing distance0.20.31.1-0.10.10.0-0.1-0.60.7-0.0-0.30.10.50.81.00.9-1.0-0.3-0.9-0.90.3-0.40.20.40.50.40.6
Locomotor testing rearing0.10.21.1-0.40.3-0.4-0.3-0.40.0-0.6-0.7-0.6-0.20.30.2-0.0-0.1-1.0-0.0-0.2-0.60.5-0.7-0.5-0.5-0.6-0.1
Locomotion in novel chamber0.10.10.2-0.4-0.3-0.5-0.3-0.4-0.4-0.4-0.5-0.4-0.30.1-0.2-0.30.2-0.20.2-0.0-0.0-0.00.2-0.10.10.00.1
Locomotion in novel chamber post-restriction0.50.82.1-1.4-1.2-1.3-1.1-1.5-1.0-1.3-1.4-1.3-1.10.8-0.2-0.60.2-0.10.5-0.0-1.00.90.0-0.7-0.1-0.3-0.3
Fecal boli incidents, locomotor time 10.71.02.70.10.80.31.10.8-0.40.20.70.1-0.6-0.9-0.8-0.90.9-1.61.11.3-1.31.3-1.4-0.9-1.2-1.3-1.5
Change in fecal boli incidents, locomotor task0.40.41.10.40.40.2-0.5-0.50.9-0.1-0.50.10.90.30.80.9-0.80.6-1.0-0.71.0-1.0-0.10.30.10.20.7
Time >=10cm from walls, locomotor time 11.41.53.0-0.50.2-0.8-1.2-1.6-0.6-1.7-1.6-1.6-0.7-0.5-0.8-0.90.8-1.50.81.1-1.21.2-1.7-1.7-1.6-1.7-1.0
Bouts of movement, locomotor time 10.10.10.30.60.20.30.10.10.20.40.30.40.4-0.4-0.10.10.1-0.2-0.2-0.20.4-0.30.30.40.20.40.4
Total resting periods, locomotor time 10.10.10.40.60.30.50.30.20.40.50.40.60.5-0.40.00.3-0.0-0.0-0.3-0.00.4-0.40.10.40.10.30.2
Rest time, locomotor task time 10.30.40.90.60.60.90.50.80.90.90.90.80.70.20.80.8-0.80.3-0.7-0.00.2-0.2-0.30.50.10.10.2
Distance moved, locomotor task time 10.20.41.2-0.8-0.8-0.9-1.0-1.0-0.6-1.0-1.1-0.9-0.50.5-0.1-0.20.10.20.1-0.4-0.0-0.00.5-0.20.20.20.1
Vertical activity count, locomotor time 10.51.23.7-1.4-1.4-1.7-1.8-1.6-1.4-1.7-1.9-1.7-1.30.5-0.8-1.00.7-0.40.8-0.0-0.1-0.00.3-0.80.0-0.1-0.1
Time >=10cm from walls, locomotor time 20.20.31.3-0.3-0.1-0.3-1.0-1.10.3-0.8-1.0-0.70.20.60.60.5-0.60.4-0.60.5-0.30.3-0.6-0.3-0.2-0.3-0.7
Bouts of movement, locomotor time 20.71.12.40.1-0.40.3-0.4-0.00.90.40.20.70.91.11.31.2-1.31.2-1.3-0.81.5-1.51.21.31.41.41.3
Total resting periods, locomotor time 21.12.04.30.6-0.00.9-0.00.51.51.00.71.31.51.21.81.8-1.81.4-1.8-1.12.1-2.11.21.81.61.61.6
Rest time, locomotor task time 20.70.93.41.31.61.00.90.70.70.60.60.50.7-1.6-0.5-0.20.6-1.20.21.0-0.10.2-1.8-0.7-1.5-1.4-0.7
Distance moved, locomotor task time 20.81.02.1-1.5-1.3-1.5-1.4-1.2-1.3-1.3-1.4-1.4-1.30.7-0.5-0.80.40.50.70.2-0.80.70.4-0.70.1-0.0-0.9
Vertical activity count, locomotor time 20.50.72.0-1.2-1.0-1.2-1.2-1.4-1.0-1.1-1.2-1.2-1.00.6-0.3-0.50.20.20.50.4-0.60.50.2-0.60.0-0.1-0.8
Light reinforcement 11.02.44.1-1.0-0.6-1.6-1.4-1.2-1.7-1.9-1.9-2.0-1.6-1.0-1.9-1.91.9-1.51.81.1-1.41.4-1.0-2.0-1.5-1.5-1.1
Light reinforcement 21.01.53.0-0.30.4-0.7-0.3-0.6-1.0-1.1-1.1-1.3-0.9-1.2-1.4-1.31.4-1.61.31.3-1.21.2-1.5-1.7-1.7-1.7-1.4
Bone: marrow area0.61.45.00.40.90.7-0.6-1.02.0-0.3-0.20.01.51.32.22.0-2.10.7-2.0-1.50.6-0.6-0.80.50.1-0.11.2
Bone: maximum diameter0.71.43.71.81.81.71.21.01.91.11.11.31.9-0.51.11.4-1.00.1-1.4-0.40.9-0.8-0.80.6-0.3-0.10.4
Bone: maximum force0.71.23.2-1.3-0.9-1.4-1.5-1.8-1.1-1.8-1.6-1.6-1.20.4-0.6-0.90.6-0.50.80.2-1.21.1-0.4-1.1-0.5-0.7-0.4
Bone: maximum moment0.40.72.0-1.1-0.6-1.0-1.1-1.4-0.8-1.4-1.2-1.2-0.90.4-0.3-0.50.3-0.20.50.1-1.00.9-0.3-0.8-0.4-0.5-0.3
Mean time between licks in bursts1.02.45.82.32.32.42.01.62.32.02.12.12.2-0.71.21.7-1.2-0.3-1.6-0.21.0-0.9-0.91.0-0.2-0.00.4
Mean num. licks in bursts0.81.24.5-1.8-2.1-1.7-1.2-0.5-1.6-1.0-1.0-1.1-1.61.2-0.4-0.90.40.80.8-0.4-0.20.11.60.01.00.90.4
Cd content in liver2.62.96.0-0.50.3-0.70.30.2-1.7-0.9-0.4-1.1-1.7-1.6-2.2-2.22.2-1.72.32.1-2.22.2-1.7-2.1-2.0-2.1-2.4
Co content in liver1.41.73.2-1.6-1.2-1.7-1.5-1.4-1.7-1.7-1.7-1.8-1.80.3-1.0-1.41.0-0.61.40.6-1.31.2-0.3-1.4-0.7-0.9-0.9
Cu content in liver0.30.42.2-0.5-1.0-0.7-0.3-0.2-1.00.2-0.2-0.0-0.70.1-0.6-0.60.50.50.5-0.30.3-0.31.50.40.80.90.6
Fe content in liver0.80.92.2-1.4-1.0-1.3-0.9-0.9-1.4-1.4-1.1-1.2-1.50.3-0.9-1.20.9-0.21.20.4-1.00.9-0.1-1.0-0.3-0.5-0.4
K content in liver0.40.41.30.80.90.60.90.80.00.70.70.60.2-1.2-0.7-0.40.7-0.90.40.6-0.30.4-0.6-0.3-0.7-0.5-0.4
Mg content in liver1.41.54.42.12.11.71.71.51.31.61.41.41.4-1.7-0.10.50.1-1.2-0.40.50.20.0-1.20.1-1.0-0.7-0.2
Mn content in liver1.51.65.42.12.31.81.60.81.41.01.10.91.4-1.8-0.10.40.2-1.2-0.41.0-0.30.4-2.0-0.4-1.6-1.3-1.0
Na content in liver0.50.51.9-0.3-0.7-0.4-0.4-0.6-0.1-0.1-0.30.10.10.50.20.2-0.20.7-0.3-1.11.0-1.01.30.71.01.11.4
Rb content in liver0.91.12.20.51.10.30.71.0-0.40.20.30.0-0.4-1.4-1.1-1.01.2-1.51.01.3-1.31.3-1.5-1.1-1.4-1.4-1.2
Se content in liver3.03.68.02.41.72.41.51.32.72.31.92.32.8-0.12.02.4-2.00.9-2.4-1.22.0-1.90.42.00.91.21.4
Sr content in liver0.10.10.70.10.50.30.4-0.00.3-0.20.3-0.10.1-0.10.10.1-0.0-0.10.00.2-0.30.3-0.9-0.4-0.5-0.7-0.6
Zn content in liver0.20.30.80.60.80.50.60.50.30.50.50.30.2-0.7-0.2-0.10.3-0.60.20.5-0.40.4-0.9-0.4-0.8-0.8-0.6
Bone: minimum diameter0.30.62.21.11.51.10.4-0.11.40.30.30.41.3-0.40.81.0-0.7-0.5-1.0-0.10.4-0.3-1.3-0.0-0.7-0.7-0.0
Time in familiar zone, hab. session 10.30.31.7-0.5-0.9-0.40.30.5-0.80.30.50.3-0.70.3-0.5-0.50.40.30.5-0.10.1-0.11.30.50.90.90.3
Time in novel zone, hab. session 10.30.30.70.10.40.2-0.5-0.70.8-0.3-0.5-0.30.60.40.90.7-0.80.5-0.8-0.40.2-0.2-0.7-0.1-0.3-0.40.1
Total zone transitions, hab. session 10.20.20.70.80.70.60.80.60.30.60.70.60.4-0.8-0.3-0.10.3-0.60.10.3-0.00.1-0.40.0-0.4-0.2-0.0
Total locomotion distance, hab. session 10.40.51.70.70.90.50.90.8-0.00.50.60.40.1-1.2-0.8-0.50.8-1.30.60.9-0.60.6-0.8-0.4-0.8-0.7-0.7
Locomotion velocity, hab. session 10.10.20.80.60.60.50.70.60.10.50.50.50.2-0.7-0.4-0.20.4-0.90.20.4-0.20.3-0.4-0.1-0.4-0.3-0.2
Time in familiar zone, hab. session 20.50.61.6-1.0-1.3-1.1-0.9-1.1-1.0-1.0-1.0-0.9-0.90.5-0.5-0.60.4-0.20.5-0.4-0.10.00.9-0.10.50.50.7
Time in novel zone, hab. session 20.20.31.60.10.20.40.10.40.60.50.40.40.50.50.80.7-0.81.3-0.6-0.20.4-0.40.00.40.30.2-0.1
Total zone transitions, hab. session 20.71.02.20.00.3-0.40.1-0.4-0.9-0.7-0.5-0.7-0.7-1.3-1.5-1.31.5-1.51.21.0-1.01.0-1.0-1.2-1.2-1.2-0.8
Total locomotion distance, hab. session 21.72.25.30.61.00.00.90.5-1.0-0.20.0-0.3-0.7-2.3-2.2-1.72.2-2.31.71.9-1.61.7-1.6-1.6-1.9-1.8-1.6
Locomotion velocity, hab. session 21.62.26.01.01.30.41.20.9-0.60.20.40.1-0.4-2.4-2.0-1.52.0-2.41.51.9-1.41.5-1.7-1.4-1.9-1.7-1.5
Novel to familiar place preference ratio0.30.31.00.40.20.50.40.50.50.60.60.60.50.20.50.6-0.51.0-0.5-0.30.6-0.60.40.70.50.60.3
Novelty place preference0.50.61.90.40.10.50.30.40.80.60.60.70.70.50.90.9-0.91.4-0.9-0.70.9-0.90.70.90.80.90.7
Time in novel zone, NPP test0.80.82.80.30.00.50.20.30.90.60.60.70.80.81.11.1-1.11.7-1.1-0.91.1-1.10.81.11.01.10.9
Total zone transitions, NPP test1.11.54.11.31.51.01.81.4-0.00.91.20.80.1-2.0-1.3-0.81.3-1.41.01.5-0.91.0-1.4-0.8-1.5-1.3-1.4
Total locomotion distance, NPP test2.43.37.10.91.50.61.61.3-0.90.40.80.2-0.7-2.6-2.2-1.82.3-2.22.02.7-2.02.2-2.2-1.7-2.3-2.2-2.6
Locomotion velocity, NPP test3.24.49.81.21.80.71.91.6-0.90.51.00.3-0.7-3.1-2.6-2.12.6-2.72.23.0-2.32.4-2.5-1.9-2.7-2.5-2.9
Intraocular pressure0.40.51.2-0.6-0.5-0.7-0.00.5-1.1-0.6-0.3-0.6-1.0-0.4-1.1-1.11.0-0.91.10.6-0.90.8-0.0-0.6-0.4-0.3-0.8
Delta distance traveled before/after self-admin3.23.37.5-0.8-1.3-0.3-1.2-1.11.00.2-0.30.30.82.72.42.0-2.42.7-2.0-2.22.1-2.22.11.92.42.32.3
Delta ambulatory time before/after self-admin2.32.96.4-0.6-1.1-0.2-1.2-1.11.00.2-0.40.30.92.42.21.9-2.22.5-2.0-2.02.1-2.21.91.82.22.12.2
Parametrial fat weight2.76.411.3-2.5-1.8-3.0-2.3-2.1-3.2-3.1-3.0-3.4-3.2-0.6-2.8-3.12.8-1.53.01.4-2.82.6-1.1-3.0-1.9-2.1-1.7
Pavlov. Cond. lever latency4.45.512.9-3.5-3.2-3.6-3.4-3.1-3.0-3.5-3.5-3.5-3.11.4-1.3-2.11.3-0.11.9-0.1-1.41.20.8-1.70.1-0.3-0.0
Pavlov. Cond. magazine entry latency3.54.57.82.31.52.41.91.62.72.62.42.72.80.22.12.6-2.21.5-2.5-1.52.5-2.31.02.41.41.71.6
Pavlov. Cond. change in total contacts2.32.44.31.61.11.71.10.82.01.91.61.92.10.31.72.0-1.71.1-2.0-1.21.8-1.70.71.81.11.31.3
Pavlov. Cond. index score3.84.910.23.12.73.22.82.43.03.23.03.23.1-0.91.62.3-1.60.5-2.2-0.51.9-1.7-0.12.00.50.80.6
Pavlov. Cond. latency score4.15.210.93.22.83.32.92.53.13.23.13.33.2-1.01.72.4-1.70.5-2.3-0.52.0-1.8-0.22.00.40.80.7
Pavlov. Cond. lever contacts3.44.010.43.23.23.13.02.62.42.92.92.82.5-1.90.71.4-0.6-0.6-1.20.70.7-0.5-1.40.8-0.8-0.5-0.6
Pavlov. Cond. magazine entry number2.32.95.2-1.9-1.3-2.1-1.6-1.3-2.2-2.2-2.0-2.3-2.3-0.1-1.7-2.01.7-1.12.01.1-1.91.8-0.7-1.9-1.1-1.3-1.2
Pavlov. Cond. intertrial magazine entries1.72.04.3-1.3-0.9-1.4-0.6-0.4-2.1-1.2-1.0-1.4-2.0-0.5-1.8-2.01.8-1.02.01.3-1.81.8-0.4-1.5-0.9-1.1-1.4
Pavlov. Cond. lever-magazine prob. diff.3.74.69.83.12.63.12.72.42.83.13.03.13.0-0.91.52.2-1.50.4-2.1-0.41.8-1.6-0.11.90.40.80.6
Pavlov. Cond. response bias2.73.37.22.62.22.62.31.92.52.72.52.62.6-0.71.41.9-1.40.5-1.8-0.41.6-1.4-0.11.60.40.70.5
Pavlov. Cond. lever latency0.40.51.70.40.70.10.1-0.00.0-0.4-0.3-0.40.0-0.9-0.6-0.40.6-1.00.40.8-0.70.7-1.3-0.9-1.2-1.1-0.9
Pavlov. Cond. magazine entry latency0.30.41.00.80.91.00.90.90.90.81.00.90.8-0.10.60.7-0.50.3-0.6-0.10.4-0.3-0.20.50.10.10.1
Pavlov. Cond. change in total contacts0.71.22.5-0.2-0.60.2-0.10.10.60.50.50.70.51.41.41.1-1.41.5-1.1-1.41.2-1.21.41.41.61.51.4
Pavlov. Cond. index score0.50.61.10.20.00.60.40.40.70.80.80.80.60.71.00.9-1.01.0-0.9-0.80.9-0.90.81.11.01.00.9
Pavlov. Cond. latency score0.40.51.00.0-0.10.30.20.20.60.60.60.70.50.80.90.8-1.01.0-0.8-0.90.8-0.80.91.01.01.00.9
Pavlov. Cond. lever contacts0.30.41.3-0.4-0.7-0.2-0.2-0.1-0.10.20.20.3-0.10.80.50.3-0.50.9-0.3-0.80.5-0.61.10.81.01.00.8
Pavlov. Cond. magazine entry number0.00.10.2-0.2-0.4-0.3-0.4-0.3-0.2-0.3-0.4-0.3-0.10.2-0.0-0.0-0.00.1-0.0-0.30.1-0.10.2-0.00.20.10.3
Pavlov. Cond. intertrial magazine entries0.50.81.71.20.81.10.80.41.21.10.91.11.3-0.20.71.0-0.70.1-1.0-0.71.0-0.90.20.90.40.60.9
Pavlov. Cond. lever-magazine prob. diff.0.30.40.80.20.00.40.30.40.60.60.70.70.50.60.80.8-0.80.8-0.7-0.70.7-0.70.70.90.80.80.7
Pavlov. Cond. response bias0.30.40.80.30.20.50.50.50.50.80.80.80.50.40.60.6-0.60.6-0.6-0.50.7-0.70.70.90.80.80.6
Time in closed arm before self-admin0.20.30.90.20.00.40.30.20.70.40.30.40.60.40.80.7-0.80.5-0.7-0.40.9-1.00.20.50.30.30.4
Time in closed arm after self-admin0.10.10.30.00.20.10.30.2-0.0-0.00.1-0.1-0.1-0.2-0.1-0.20.2-0.10.20.3-0.50.5-0.5-0.4-0.5-0.5-0.3
Time in open arm before self-admin1.21.42.20.90.51.10.81.11.31.51.31.51.30.41.21.4-1.21.2-1.3-1.31.0-1.01.01.51.11.21.0
Time in open arm after self-admin0.70.81.50.20.00.60.30.50.80.90.80.90.70.91.21.1-1.20.8-1.0-1.11.0-1.00.91.21.11.10.9
Bone: periosteal estimation0.40.92.90.00.30.3-0.8-1.01.3-0.5-0.5-0.21.01.21.71.5-1.60.6-1.5-1.40.7-0.7-0.20.40.30.21.2
Bone: periosteal perimeter0.40.72.00.80.70.80.1-0.31.40.40.20.51.30.31.21.3-1.20.4-1.4-0.81.0-1.0-0.20.60.20.20.7
Bone: post-yield work0.50.83.31.01.61.00.80.30.90.30.60.40.7-0.90.00.20.0-1.0-0.20.7-0.60.6-1.8-0.6-1.3-1.3-0.8
Progressive ratio test 1 active lever presses0.10.20.60.30.60.50.70.60.30.50.80.60.2-0.00.30.2-0.20.1-0.10.4-0.50.6-0.20.2-0.0-0.0-0.5
Progressive ratio test 1 breakpoint0.10.20.60.30.60.60.70.60.30.50.80.60.30.00.30.3-0.30.2-0.20.3-0.50.5-0.20.2-0.0-0.0-0.4
Progressive ratio test 1 inactive lever presses0.81.12.2-0.6-0.1-0.8-0.2-0.5-1.3-0.9-0.5-0.9-1.3-0.8-1.4-1.51.4-1.11.51.3-1.41.4-0.8-1.2-1.0-1.1-1.1
Progressive ratio test 2 active lever presses0.10.10.40.30.40.30.60.3-0.10.50.60.5-0.1-0.4-0.4-0.30.3-0.20.30.4-0.10.20.10.1-0.00.0-0.1
Progressive ratio test 2 breakpoint0.10.10.40.20.30.20.60.3-0.10.50.60.5-0.0-0.3-0.3-0.20.3-0.00.20.3-0.10.10.30.20.10.2-0.0
Progressive ratio test 2 inactive lever presses0.40.72.11.11.41.31.20.90.91.21.41.20.8-0.60.30.4-0.30.1-0.30.7-0.10.2-0.80.2-0.5-0.4-0.6
Incentive Sensitization - Responses0.10.20.50.60.50.50.60.20.30.70.70.70.4-0.3-0.00.20.0-0.1-0.2-0.10.6-0.60.40.50.30.40.6
Incentive Sensitization - Breakpoint0.10.10.30.50.40.30.60.20.10.60.50.50.2-0.5-0.3-0.10.3-0.30.10.00.4-0.40.30.30.20.20.5
Sum of active levers in priming session hrs 5-60.80.71.30.70.71.00.60.81.11.11.11.11.00.41.11.1-1.00.4-1.0-0.40.9-0.90.10.90.50.60.3
Progressive ratio2.33.711.4-2.9-2.9-2.9-3.4-2.6-1.6-2.9-3.1-2.7-1.92.20.1-0.6-0.10.80.4-1.4-0.1-0.11.3-0.60.90.51.4
Food seeking constrained by brief footshock0.20.20.6-0.4-0.5-0.2-0.2-0.5-0.10.10.00.0-0.10.80.50.3-0.50.7-0.3-0.20.3-0.30.80.50.80.70.4
Seeking ratio, punishment vs. effort1.82.67.12.42.02.42.71.81.82.72.62.51.9-1.10.71.2-0.70.1-1.10.51.0-0.8-0.31.20.10.4-0.4
Retroperitoneal fat weight0.52.33.9-0.8-0.3-1.1-0.4-0.8-1.7-1.3-1.0-1.4-1.7-1.2-1.9-2.01.9-1.32.01.6-1.91.8-1.2-1.9-1.6-1.7-1.7
Reaction time number correct0.71.43.9-1.9-2.0-1.7-1.6-1.8-1.5-1.6-1.4-1.6-1.61.1-0.4-0.90.40.90.9-0.2-0.80.60.7-0.60.30.10.0
Reaction time mean minus median0.81.95.32.12.12.12.32.21.61.91.91.91.7-1.30.30.9-0.3-0.3-0.80.40.5-0.4-0.80.6-0.4-0.2-0.0
Reaction time mean minus median AUC1.02.57.12.32.42.42.72.71.62.32.42.21.7-1.60.20.8-0.2-0.4-0.60.80.10.1-1.10.6-0.7-0.4-0.6
Reaction time num false alarms0.30.51.10.80.60.6-0.00.31.00.50.30.61.10.10.80.9-0.80.1-1.0-0.70.7-0.70.30.80.50.60.9
Reaction time num false alarms AUC0.71.12.40.70.30.6-0.3-0.11.30.50.20.71.30.61.31.4-1.30.7-1.5-1.31.4-1.30.81.21.01.11.5
Reaction time trials correct on left0.71.43.9-1.9-2.0-1.7-1.6-1.8-1.5-1.6-1.4-1.6-1.61.1-0.4-0.90.40.90.9-0.2-0.80.60.7-0.60.30.10.0
Reaction time trials on left0.71.33.7-1.9-1.9-1.7-1.6-1.8-1.4-1.6-1.4-1.5-1.61.1-0.4-0.80.30.90.8-0.2-0.80.60.6-0.60.30.10.0
Reaction time mean1.72.67.42.42.72.12.32.31.31.71.71.51.4-2.3-0.40.20.5-1.3-0.11.7-0.50.7-2.2-0.4-1.7-1.4-1.5
Reaction time mean AUC1.52.46.92.32.62.02.22.11.21.61.71.51.3-2.2-0.40.20.5-1.2-0.11.7-0.50.7-2.0-0.3-1.6-1.3-1.5
Median of all reaction times1.52.15.41.92.31.61.81.80.81.21.21.00.9-2.1-0.7-0.20.7-1.50.31.9-0.91.0-2.2-0.7-1.8-1.6-1.8
Reaction time omissions1.01.44.71.72.21.51.81.21.01.11.21.21.0-1.7-0.30.10.4-1.6-0.10.8-0.50.6-1.6-0.3-1.2-1.0-0.8
Reaction time false alarm rate1.62.25.21.81.41.70.81.02.21.51.21.72.30.01.62.0-1.60.3-2.0-1.21.8-1.60.41.60.81.11.5
Reaction time premature initiation rate0.10.10.4-0.40.0-0.30.0-0.2-0.3-0.4-0.4-0.4-0.40.20.0-0.20.0-0.40.30.1-0.70.6-0.6-0.5-0.4-0.5-0.5
Reaction time premature initiations0.50.92.6-1.6-1.2-1.4-1.0-1.3-1.1-1.4-1.3-1.4-1.30.9-0.2-0.70.20.20.7-0.1-1.00.8-0.1-0.8-0.1-0.4-0.4
Std. dev. reaction times1.52.76.32.52.42.52.32.22.32.32.22.32.3-1.01.01.6-1.00.2-1.50.11.0-0.8-0.71.1-0.20.10.2
Reaction time trials completed0.71.33.7-1.9-1.9-1.7-1.6-1.8-1.4-1.6-1.4-1.5-1.61.1-0.4-0.80.30.90.8-0.2-0.80.60.6-0.60.30.10.0
Reaction time trials AUC0.71.43.4-1.8-1.8-1.7-1.5-1.8-1.5-1.6-1.4-1.6-1.60.9-0.6-1.00.60.71.0-0.1-0.90.70.5-0.80.1-0.1-0.1
Run reversals in cocaine runway, females0.50.52.0-0.7-0.7-0.7-0.50.2-0.9-0.7-0.3-0.6-1.00.0-0.6-0.80.6-0.10.90.8-1.41.4-0.1-0.6-0.3-0.4-0.8
Run reversals in cocaine runway, males0.60.62.21.11.21.21.51.11.01.01.11.11.0-0.40.40.6-0.40.1-0.6-0.20.6-0.5-0.60.4-0.2-0.10.1
Latency to leave start box in cocaine runway0.81.02.61.41.61.21.40.90.70.90.90.80.7-1.5-0.5-0.10.5-1.30.21.0-0.50.7-1.4-0.4-1.2-1.1-0.8
Latency to leave start box in cocaine runway, F0.81.02.91.21.41.11.31.00.50.71.00.80.6-1.4-0.5-0.20.5-1.70.20.8-1.11.2-1.2-0.3-1.0-0.9-0.7
Latency to leave start box in cocaine runway, M0.20.20.50.40.50.20.2-0.20.10.1-0.1-0.10.1-0.7-0.4-0.20.4-0.10.20.60.3-0.3-0.7-0.5-0.7-0.7-0.4
Std. dev. time between licks in bursts1.72.36.52.12.22.31.51.12.51.71.61.82.4-0.41.62.0-1.5-0.2-1.9-0.51.1-1.0-1.00.9-0.2-0.10.5
Total sessions with >9 infusions0.50.71.5-0.0-0.20.40.40.80.50.60.70.80.51.01.10.9-1.11.2-0.9-0.90.3-0.31.01.11.21.20.6
Short access day 1 total inactive lever presses0.60.82.31.11.21.51.10.81.21.31.51.31.1-0.20.90.9-0.90.7-0.80.1-0.40.5-0.80.5-0.2-0.2-0.4
Short access day 10 total inactive lever presses0.30.82.40.60.90.10.20.0-0.3-0.3-0.2-0.3-0.2-1.6-1.3-0.91.3-1.40.91.2-0.60.7-1.2-1.0-1.2-1.1-0.4
Short access day 1 total infusions0.60.82.70.70.71.11.21.70.91.21.41.30.90.31.00.9-1.01.1-0.8-0.2-0.00.10.10.90.50.5-0.1
Short access day 10 total infusions0.10.10.80.10.20.30.70.9-0.10.40.70.5-0.1-0.0-0.1-0.10.0-0.20.20.1-0.60.60.10.30.20.2-0.2
Short access total infusions0.30.41.70.30.40.70.91.30.40.81.11.00.40.20.60.5-0.60.6-0.30.0-0.40.50.10.60.40.4-0.3
Short access day 1 locomotion0.40.51.61.00.90.81.31.20.40.70.80.80.5-1.0-0.4-0.00.4-1.00.10.3-0.10.3-0.50.1-0.4-0.2-0.1
Short access day 10 total locomotion0.50.82.2-0.3-0.1-0.2-0.8-1.40.9-0.6-0.8-0.20.71.31.41.2-1.40.7-1.3-1.50.7-0.80.30.50.60.61.2
Short access total locomotion0.10.10.30.30.40.40.40.00.50.00.10.30.50.10.50.5-0.4-0.2-0.5-0.1-0.20.2-0.50.1-0.2-0.1-0.1
One hour access (0.3 mA shock)0.50.51.81.01.00.61.31.20.10.90.80.70.3-1.3-0.9-0.40.8-1.10.40.30.5-0.4-0.10.0-0.3-0.10.1
Compulsive drug intake1.61.97.41.82.20.91.21.10.40.30.20.20.6-2.7-1.6-0.81.6-2.60.71.1-0.20.4-2.0-1.2-2.1-1.8-0.5
One hour access (shock baseline)0.20.31.3-0.6-0.8-0.30.10.3-0.40.40.40.3-0.40.80.20.0-0.30.90.0-0.60.2-0.31.20.71.00.90.3
Social response proportion0.10.10.60.00.30.2-0.3-0.20.6-0.2-0.2-0.10.40.50.80.6-0.70.5-0.6-0.10.0-0.0-0.40.0-0.1-0.20.0
Social responses0.40.51.3-0.2-0.2-0.1-0.6-0.60.6-0.2-0.3-0.10.51.01.20.9-1.10.9-1.0-0.90.5-0.50.50.50.60.51.0
Social time0.81.14.21.82.01.41.40.91.30.80.80.91.4-1.5-0.10.50.1-1.4-0.50.40.10.0-1.4-0.1-1.0-0.80.1
Soleus weight0.72.17.32.22.72.11.10.82.51.00.91.02.3-1.01.31.6-1.1-0.6-1.60.20.3-0.1-2.2-0.0-1.3-1.1-0.4
Bone: stiffness0.91.53.1-1.3-1.0-1.5-1.3-1.7-1.5-1.8-1.6-1.7-1.5-0.1-1.2-1.41.2-1.01.30.4-1.31.2-0.3-1.3-0.7-0.8-0.5
Tibialis anterior weight0.20.81.9-1.2-1.1-1.4-1.2-0.9-1.4-1.1-1.2-1.1-1.30.3-0.8-1.00.8-0.41.0-0.1-0.80.70.5-0.60.1-0.00.1
Time to tail flick, vehicle, before self-admin1.21.34.4-0.0-0.2-0.8-0.4-0.5-1.2-1.0-1.1-1.0-0.8-1.5-1.9-1.51.9-2.11.31.50.1-0.1-0.4-1.2-1.0-0.9-0.7
Time to tail flick, vehicle, after self-admin0.30.51.01.00.80.90.60.80.90.80.81.01.0-0.30.50.7-0.5-0.2-0.7-0.50.7-0.70.00.60.20.30.2
Time to tail flick, test, before self-admin0.30.41.6-0.4-0.9-0.5-0.2-0.3-0.2-0.3-0.4-0.1-0.10.60.20.2-0.20.5-0.3-0.90.3-0.31.30.61.01.01.2
Time to tail flick, test, after self-admin0.60.62.11.00.61.01.01.40.61.41.41.30.7-0.40.10.4-0.20.1-0.3-0.30.6-0.50.60.90.50.70.5
Delta time to tail flick, vehicle, before/after SA0.90.82.60.70.61.21.01.40.81.41.61.40.80.30.90.9-0.91.0-0.7-0.60.00.10.31.00.60.7-0.1
Delta time to tail flick, test, before/after SA0.80.91.80.40.70.20.50.7-0.50.30.50.0-0.5-1.3-1.2-1.01.2-1.11.11.4-0.91.0-1.1-0.9-1.2-1.2-1.3
Tibia length0.20.62.1-0.10.40.1-1.0-1.41.1-0.8-0.8-0.60.70.91.41.1-1.30.0-1.1-0.6-0.30.2-1.1-0.2-0.4-0.50.2
Ambulatory time before self-admin0.30.41.80.10.5-0.10.50.3-0.4-0.3-0.1-0.3-0.4-0.8-0.8-0.70.8-1.30.70.3-0.80.8-0.8-0.8-0.9-0.9-0.5
Ambulatory time after self-admin0.50.61.7-0.6-0.6-0.5-0.7-0.90.3-0.4-0.7-0.40.11.21.00.7-1.00.8-0.7-1.30.9-1.00.50.40.70.61.2
Bone: tissue strength0.30.31.1-0.30.2-0.2-0.1-0.1-0.4-0.4-0.2-0.3-0.5-0.2-0.4-0.50.4-0.40.60.8-1.11.0-0.7-0.7-0.7-0.7-1.0
Total heroin consumption0.00.10.20.20.20.20.10.10.30.10.10.10.3-0.00.20.3-0.2-0.1-0.3-0.30.5-0.50.10.20.10.10.3
Bone: trabecular number1.32.14.90.30.5-0.01.21.8-1.40.30.70.2-1.1-1.9-2.2-1.92.2-1.72.01.9-1.71.8-0.8-1.1-1.2-1.1-1.7
Bone: trabecular spacing1.31.73.8-0.5-0.8-0.3-1.5-1.81.0-0.6-1.0-0.50.81.92.01.6-1.91.7-1.7-1.61.3-1.40.70.81.11.01.3
Bone: trabecular thickness1.51.94.5-0.10.4-0.40.60.9-1.5-0.20.1-0.3-1.3-1.7-2.1-1.92.1-1.72.01.7-1.81.8-0.9-1.4-1.4-1.3-1.6
Bone: trabecular tissue density1.62.46.50.1-0.40.6-0.0-0.31.40.70.71.01.21.82.01.9-2.02.6-1.9-2.01.7-1.81.61.91.91.91.9
Water consumed over 24 hours0.10.10.30.60.50.40.2-0.10.60.30.20.30.6-0.20.30.4-0.30.2-0.4-0.10.3-0.2-0.20.1-0.1-0.10.1
Number of responses in last shaping day2.32.56.01.01.01.40.60.92.21.31.01.52.01.22.52.4-2.41.6-2.4-1.61.4-1.30.41.71.11.11.3