Rnf135

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Rnf135 0.07 0.05 3.0e-07 0.05 0.04 0.04 0.04 5.5e-06 8.0e-06 4.0e-05 1.3e-05
2 Liver intron excision ratio chr10_65672884_65676452 0.22 0.15 8.1e-03 0.01 0 0 0.01 6.1e-02 1.6e-01 2.9e-01 5.1e-02
3 pVTA gene expression Rnf135 0.04 0.03 4.0e-05 0.05 0.06 0.05 0.05 5.0e-05 1.9e-05 5.0e-05 6.9e-05
4 LHb gene expression Rnf135 0.19 0.12 1.5e-04 0.1 0.14 0.12 0.13 2.0e-03 4.2e-04 7.5e-04 4.7e-04
5 IL gene expression Rnf135 0.26 0.13 2.1e-07 0.21 0.32 0.28 0.32 1.0e-05 1.8e-08 1.5e-07 1.5e-08
6 IC gene expression Rnf135 0.2 0.1 1.6e-09 0.23 0.2 0.21 0.21 4.4e-10 5.0e-09 3.3e-09 4.1e-09
7 OFC gene expression Rnf135 0.14 0.1 2.3e-03 0.1 0.11 0.06 0.11 3.0e-03 1.7e-03 1.2e-02 1.4e-03
8 Liver gene expression Rnf135 0.12 0.07 2.1e-11 0.09 0.08 0.07 0.08 5.1e-10 4.2e-09 1.2e-08 2.4e-09
9 NAcc gene expression Rnf135 0.17 0.09 0.0e+00 0.23 0.25 0.25 0.25 9.2e-34 2.1e-37 3.6e-37 7.2e-37
10 BLA gene expression Rnf135 0.17 0.09 1.9e-07 0.1 0.13 0.14 0.13 3.5e-06 1.5e-07 1.2e-07 2.8e-07
11 PL gene expression Rnf135 0.13 0.06 0.0e+00 0.21 0.24 0.24 0.24 1.0e-22 3.2e-26 2.6e-26 3.8e-26
12 Brain gene expression Rnf135 0.2 0.1 0.0e+00 0.27 0.28 0.28 0.28 4.3e-25 9.3e-26 8.5e-26 1.1e-25
13 Liver alternative TSS NM_001012010.2 0.02 0.02 6.9e-03 0.01 0.01 0 0.01 3.0e-02 1.2e-02 1.2e-01 4.6e-02
14 Liver alternative TSS XM_039086023.2 0.02 0.02 9.2e-03 0.01 0.01 0 0.01 3.6e-02 1.4e-02 2.3e-01 3.4e-02
15 Brain mRNA stability Rnf135 0.14 0.08 3.5e-13 0.15 0.14 0.14 0.15 5.9e-14 3.1e-13 6.5e-13 6.6e-14
16 NAcc mRNA stability Rnf135 0.05 0.04 6.7e-06 0.04 0.04 0.06 0.04 3.6e-06 4.0e-06 6.5e-09 2.5e-06
17 Liver mRNA stability Rnf135 0.03 0.03 3.2e-03 0.01 0 -0 0 3.8e-02 8.4e-02 5.8e-01 1.9e-01
18 LHb mRNA stability Rnf135 0.12 0.09 3.8e-03 0.14 0.1 0.12 0.11 4.2e-04 2.3e-03 9.3e-04 1.8e-03
19 PL mRNA stability Rnf135 0.03 0.02 5.9e-05 0.04 0.03 0.03 0.03 7.7e-05 2.2e-04 2.0e-04 1.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density2.24.05.32.1-2.2-2.1-2.1-2.22.3-2.1-1.6-2.12.02.02.1-2.12.11.91.21.71.91.9
Area under the delay curve0.00.10.40.3-0.0-0.00.1-0.10.2-0.20.5-0.00.1-0.00.00.1-0.1-0.10.6-0.10.30.3
BMI with tail0.72.38.20.8-1.6-1.9-1.9-1.61.3-0.9-2.9-1.41.31.81.5-1.51.51.60.11.70.90.9
BMI without tail0.31.42.61.1-1.2-1.1-1.2-1.11.5-1.0-0.7-1.31.31.21.3-1.31.31.60.51.30.90.9
Body weight2.19.211.03.3-3.0-3.2-3.2-3.23.0-2.9-3.0-3.23.23.33.1-3.33.33.12.23.12.52.5
Weight adjusted by age0.41.12.4-0.61.21.21.31.0-1.30.51.51.0-1.0-1.0-1.21.1-1.1-1.10.2-1.3-0.4-0.4
Bone surface0.50.91.51.1-0.9-1.1-1.0-1.21.2-1.0-0.8-1.01.01.01.0-1.11.10.90.30.70.90.9
Bone volume1.01.92.71.4-1.4-1.5-1.5-1.61.6-1.4-1.0-1.41.51.31.4-1.51.51.40.71.21.31.3
Breakpoint value in progressive ratio session0.40.82.11.4-0.7-0.4-0.5-0.70.8-0.9-0.1-0.91.20.70.7-1.01.10.91.30.80.70.7
Number of licking bursts0.10.41.9-0.70.30.10.10.60.01.30.10.4-0.5-0.5-0.10.4-0.4-0.5-0.2-0.1-1.4-1.4
Context. condit. distance diff. score0.30.41.00.5-0.7-0.6-0.6-0.70.6-0.8-0.7-0.50.50.70.6-0.60.60.4-0.10.41.01.0
Locomotion velocity, session 10.70.81.71.3-0.6-0.9-0.9-0.90.7-1.0-1.1-0.91.01.10.8-1.11.10.61.00.60.60.6
Locomotion distance, session 10.10.10.4-0.00.20.10.10.2-0.10.30.00.1-0.2-0.1-0.30.0-0.0-0.00.6-0.3-0.6-0.6
Locomotion velocity, session 20.00.00.00.00.10.10.10.0-0.2-0.00.10.0-0.10.0-0.2-0.00.0-0.0-0.1-0.1-0.0-0.0
Locomotion distance, session 20.40.61.30.8-0.8-0.8-0.8-0.70.8-0.5-0.6-0.80.70.80.7-0.80.81.01.10.60.40.4
Locomotion velocity, session 32.22.63.2-1.61.61.61.61.6-1.71.51.31.6-1.7-1.6-1.71.7-1.7-1.6-1.8-1.7-1.2-1.2
Locomotion distance, session 30.70.81.4-0.71.00.80.90.8-1.10.90.70.8-1.0-0.9-1.00.8-0.8-0.5-0.5-1.2-0.9-0.9
Stereotopy head waving bouts, day 30.20.21.0-0.40.30.60.50.3-0.60.10.50.4-0.4-0.4-0.50.3-0.3-0.3-1.0-0.6-0.1-0.1
Stereotopy head waving duration, day 30.30.30.9-0.70.30.60.60.4-0.40.30.80.5-0.6-0.7-0.60.5-0.5-0.6-1.0-0.7-0.2-0.2
Locomotion velocity, session 70.20.20.50.1-0.5-0.6-0.6-0.50.6-0.3-0.3-0.50.40.30.5-0.40.40.70.50.60.40.4
Locomotion distance, session 70.10.10.30.1-0.4-0.5-0.5-0.20.5-0.2-0.2-0.40.30.20.4-0.30.30.50.10.40.20.2
Stereotopy head waving bouts, day 70.20.20.70.9-0.4-0.1-0.1-0.60.2-0.70.6-0.50.50.30.3-0.60.60.50.30.00.40.4
Stereotopy head waving duration, day 70.10.10.40.5-0.10.10.1-0.4-0.1-0.40.7-0.20.20.10.0-0.30.30.20.2-0.10.20.2
Locomotion velocity, session 80.00.00.10.20.1-0.00.0-0.1-0.2-0.2-0.30.0-0.10.2-0.2-0.00.0-0.1-0.4-0.30.20.2
Locomotion distance, session 80.10.20.40.4-0.6-0.4-0.4-0.50.5-0.6-0.4-0.40.30.50.4-0.50.50.3-0.00.20.60.6
Degree of sensitization distance2.12.23.31.3-1.6-1.4-1.5-1.41.7-1.6-0.8-1.51.71.41.5-1.51.51.21.31.81.61.6
Degree of sensitization stereotypy0.50.61.11.1-0.7-0.6-0.6-0.90.6-0.9-0.1-0.80.80.70.7-0.90.90.80.90.50.60.6
Conditioned locomotion2.52.93.9-1.81.61.71.61.4-1.81.81.61.7-1.8-1.9-1.81.8-1.8-1.6-2.0-1.7-1.5-1.5
Cocaine response after cond. corrected1.42.13.00.9-1.5-1.6-1.6-1.61.5-1.4-1.7-1.41.21.51.6-1.41.31.3-0.01.61.61.6
Cocaine response after cond. not corrected2.03.03.91.4-2.0-1.8-1.8-2.02.0-1.7-1.7-1.71.61.71.9-1.71.71.60.11.91.81.8
Cocaine response before conditioning0.10.20.70.6-0.6-0.1-0.2-0.30.8-0.30.4-0.40.50.10.5-0.40.50.40.00.30.30.3
Saline control response0.10.10.7-0.60.20.50.40.3-0.10.20.90.4-0.4-0.4-0.30.3-0.3-0.1-0.4-0.3-0.1-0.1
Bone: connectivity density2.43.85.12.3-2.0-2.1-2.0-2.22.2-2.0-1.6-2.02.02.01.9-2.12.11.81.01.61.81.8
Bone: cortical apparent density0.00.00.2-0.5-0.10.10.10.20.10.30.40.1-0.1-0.30.00.1-0.20.10.00.1-0.1-0.1
Bone: cortical area1.01.73.2-1.71.21.41.41.3-0.91.31.81.4-1.2-1.6-1.11.4-1.4-1.2-1.1-0.9-0.9-0.9
Bone: cortical porosity0.10.10.2-0.40.10.30.30.20.10.00.50.2-0.3-0.3-0.00.2-0.2-0.4-0.2-0.30.10.1
Bone: cortical porosity0.00.00.3-0.5-0.10.10.00.10.20.00.10.1-0.3-0.10.20.2-0.2-0.2-0.3-0.10.20.2
Bone: cortical thickness1.83.06.2-2.21.42.01.91.8-1.31.72.51.8-1.6-2.1-1.51.9-1.8-1.7-1.7-1.2-1.2-1.2
Bone: cortical thickness0.10.10.6-0.40.00.30.20.20.10.40.80.1-0.0-0.4-0.10.2-0.20.00.10.3-0.2-0.2
Bone: cortical tissue density0.00.00.1-0.3-0.3-0.1-0.2-0.10.30.10.1-0.20.1-0.10.2-0.10.10.40.30.30.10.1
Condit. Reinf. active minus inactive responses0.00.00.3-0.20.1-0.1-0.00.1-0.10.2-0.40.1-0.2-0.10.00.2-0.3-0.00.5-0.1-0.2-0.2
Condit. Reinf. active-inactive response ratio0.10.10.3-0.30.50.40.40.4-0.40.40.10.4-0.4-0.4-0.30.4-0.5-0.00.1-0.4-0.3-0.3
Condit. Reinf. active responses0.00.00.2-0.0-0.2-0.3-0.3-0.20.30.0-0.5-0.10.10.10.3-0.10.10.10.20.30.00.0
Condit. Reinf. inactive responses0.00.10.20.0-0.3-0.3-0.3-0.20.3-0.1-0.2-0.10.10.30.2-0.20.2-0.3-0.40.30.10.1
Incentive salience index mean0.00.00.2-0.10.20.00.00.0-0.10.3-0.20.1-0.2-0.20.00.2-0.20.10.4-0.1-0.2-0.2
Condit. Reinf. lever presses0.10.10.40.5-0.2-0.3-0.3-0.50.2-0.3-0.2-0.30.30.30.4-0.30.30.70.40.10.40.4
Condit. Reinf. active minus inactive responses0.10.20.5-0.60.20.30.20.5-0.10.70.50.3-0.3-0.6-0.30.4-0.4-0.2-0.7-0.1-0.6-0.6
Condit. Reinf. active-inactive response ratio0.10.10.4-0.20.10.30.30.40.00.50.60.2-0.1-0.5-0.30.2-0.2-0.2-0.1-0.0-0.6-0.6
Condit. Reinf. active responses0.20.40.9-0.70.40.40.40.6-0.40.80.60.5-0.5-0.8-0.50.5-0.6-0.3-1.0-0.3-0.7-0.7
Condit. Reinf. inactive responses0.10.21.1-0.60.30.30.30.4-0.40.40.30.4-0.4-0.5-0.30.5-0.5-0.3-1.0-0.3-0.2-0.2
Condit. Reinf. lever presses0.60.91.8-1.00.80.90.91.1-0.71.21.30.8-0.8-1.3-0.90.9-0.9-0.6-0.6-0.6-1.1-1.1
Condit. Reinf. lever reinforcers received0.40.61.1-0.90.60.70.60.8-0.61.10.80.7-0.7-1.0-0.70.7-0.7-0.5-1.1-0.5-1.0-1.0
Conditioned reinforcement - actives0.10.53.3-0.80.81.00.80.6-0.60.20.70.7-0.7-0.5-0.60.5-0.5-0.6-1.8-0.6-0.0-0.0
Conditioned reinforcement - inactives1.02.85.6-1.11.82.01.91.6-1.71.72.41.6-1.4-1.9-1.71.4-1.4-1.3-0.7-1.7-1.8-1.8
Conditioned locomotion1.82.74.5-1.42.12.11.91.5-1.81.51.81.7-1.5-1.6-1.71.4-1.3-0.9-2.1-1.4-1.4-1.4
Patch foraging indifference point 0 sec0.00.10.40.0-0.1-0.1-0.1-0.10.2-0.00.4-0.20.2-0.10.2-0.0-0.00.40.60.20.10.1
Patch foraging indifference point AUC1.22.83.9-1.91.71.71.71.6-1.82.01.51.7-1.6-1.8-1.71.7-1.7-1.5-1.1-1.4-1.8-1.8
Delay disc. indifference point, 0s delay0.40.50.7-0.70.80.80.80.6-0.50.50.80.8-0.7-0.8-0.80.8-0.8-0.6-0.7-0.5-0.3-0.3
Delay disc. indifference point, 16s delay0.10.20.70.5-0.5-0.5-0.4-0.50.6-0.30.2-0.40.50.30.5-0.30.30.20.90.50.20.2
Delay disc. indifference point, 2s delay0.40.50.9-0.70.70.80.90.6-0.60.40.60.8-0.7-0.7-0.80.9-0.9-0.9-0.4-0.7-0.1-0.1
Delay disc. indifference point, 24s delay0.10.21.30.4-0.4-0.4-0.4-0.50.5-0.10.4-0.40.40.20.5-0.30.30.51.10.50.00.0
Delay disc. indifference point, 4s delay1.71.83.31.4-1.5-1.2-1.2-1.11.7-1.8-0.3-1.31.31.21.4-1.21.21.01.21.11.81.8
Delay disc. indifference point, 8s delay0.20.30.80.9-0.4-0.3-0.2-0.40.5-0.90.2-0.50.50.40.4-0.30.30.30.70.10.90.9
Indifference point function ln k3.09.012.62.9-2.7-3.4-3.2-3.12.9-3.0-3.6-3.02.83.13.1-2.82.72.92.92.72.92.9
Indifference point function log k3.09.012.62.9-2.7-3.4-3.2-3.12.9-3.0-3.6-3.02.83.13.1-2.82.72.92.92.72.92.9
Patch foraging total patch changes 0 sec0.00.10.50.0-0.00.10.10.00.10.00.7-0.10.1-0.30.10.1-0.10.30.60.10.00.0
Patch foraging total patch changes 12 sec0.40.62.3-0.50.71.01.00.7-0.90.71.50.6-0.4-0.9-0.80.7-0.6-0.5-0.2-0.5-0.7-0.7
Patch foraging total patch changes 18 sec0.61.54.7-1.21.01.51.41.5-0.91.32.21.1-0.9-1.5-1.11.2-1.1-0.9-0.9-0.9-1.1-1.1
Patch foraging total patch changes 24 sec0.51.82.6-1.21.51.41.41.5-1.11.61.51.3-1.1-1.5-1.31.3-1.3-1.0-0.9-1.1-1.6-1.6
Patch foraging total patch changes 6 sec2.03.46.5-1.81.82.02.01.8-1.72.02.51.8-1.7-2.2-1.81.9-1.9-1.4-0.9-1.7-1.8-1.8
Patch foraging time to switch 0 sec0.10.21.30.4-0.00.70.60.40.0-0.41.10.2-0.1-0.1-0.3-0.00.1-0.6-0.7-0.40.20.2
Patch foraging water rate 0 sec0.10.51.1-1.00.90.30.40.7-0.71.0-0.00.6-0.7-0.7-0.50.8-0.9-0.20.1-0.6-0.9-0.9
Patch foraging water rate 12 sec0.41.64.31.4-1.0-1.5-1.4-1.21.1-1.0-1.3-1.41.41.11.2-1.21.11.42.11.20.70.7
Patch foraging water rate 18 sec1.53.44.31.9-1.5-2.1-2.0-1.91.7-2.0-2.0-1.81.91.91.9-1.71.71.91.41.61.91.9
Patch foraging water rate 24 sec0.50.72.10.5-0.8-1.1-1.0-1.00.8-0.7-1.5-0.90.80.80.8-0.60.60.90.60.80.80.8
Patch foraging water rate 6 sec0.10.10.5-0.10.2-0.4-0.3-0.1-0.10.4-0.7-0.10.1-0.00.10.1-0.10.30.60.1-0.4-0.4
Seeking ratio, delayed vs. immediate footshock0.10.21.7-1.3-0.20.10.0-0.2-0.00.2-0.50.3-0.5-0.30.20.4-0.50.2-0.00.30.40.4
Distance traveled before self-admin0.81.74.8-0.81.31.61.71.3-1.30.62.21.3-1.2-1.4-1.41.4-1.4-1.4-0.6-1.6-0.4-0.4
Distance traveled after self-admin0.10.10.6-0.50.10.60.40.1-0.00.30.80.2-0.1-0.5-0.20.2-0.2-0.0-0.4-0.1-0.2-0.2
Extensor digitorum longus weight0.10.30.80.8-0.3-0.5-0.5-0.50.1-0.4-0.9-0.40.60.70.3-0.50.50.30.70.50.20.2
Bone: elastic displacement0.20.31.5-1.20.20.10.10.5-0.20.90.10.5-0.6-0.7-0.20.6-0.7-0.3-0.5-0.1-0.5-0.5
Bone: elastic work4.55.89.3-3.02.42.32.32.4-2.12.82.32.4-2.5-2.7-2.22.6-2.6-2.1-1.9-2.0-2.4-2.4
Bone: endosteal estimation0.10.20.6-0.20.70.40.50.4-0.50.40.60.5-0.4-0.5-0.50.4-0.4-0.50.1-0.6-0.6-0.6
Bone: endosteal perimeter0.10.30.70.6-0.3-0.7-0.6-0.70.6-0.6-0.7-0.50.50.60.6-0.50.50.60.80.30.40.4
Epididymis fat weight5.327.032.75.7-5.4-4.9-5.0-5.45.3-5.4-3.9-5.45.65.25.2-5.55.55.05.05.14.94.9
Delta time in closed arm before/after self-admin0.10.10.6-0.2-0.4-0.4-0.3-0.10.4-0.4-0.5-0.2-0.00.20.30.0-0.10.10.80.10.60.6
Delta time in open arm before/after self-admin0.60.71.70.9-0.8-0.7-0.8-0.80.8-0.3-0.5-0.80.90.70.8-1.01.10.8-1.31.00.00.0
Diff in mean of infusions in LGA sessions0.10.10.40.60.20.30.30.2-0.2-0.20.60.00.1-0.0-0.2-0.20.3-0.20.6-0.4-0.0-0.0
Delay discount exponential model param0.10.10.5-0.50.10.20.10.3-0.30.4-0.40.2-0.2-0.2-0.20.1-0.1-0.1-0.7-0.0-0.4-0.4
Extinction: sum of active levers before priming0.10.20.60.60.20.30.30.3-0.20.30.40.10.2-0.2-0.4-0.10.1-0.50.4-0.3-0.8-0.8
Active lever presses in extinction session 60.50.52.80.10.81.01.00.8-0.8-0.11.70.6-0.3-0.6-0.80.5-0.4-0.6-0.4-0.70.10.1
Bone: final force0.40.71.6-1.10.81.00.90.7-0.50.81.30.9-0.7-1.0-0.70.9-0.9-0.5-0.8-0.5-0.4-0.4
Bone: final moment0.40.71.3-1.00.91.00.90.7-0.60.81.20.9-0.7-1.0-0.70.9-0.9-0.5-0.8-0.6-0.6-0.6
Food consumed during 24 hour testing period0.20.51.6-0.50.90.60.60.7-0.60.30.60.8-0.7-0.5-0.60.7-0.7-0.7-1.3-0.9-0.0-0.0
Glucose0.40.72.5-1.60.60.80.70.6-0.50.80.90.8-1.0-1.0-0.70.9-1.0-0.8-1.2-0.5-0.3-0.3
Heart weight1.01.72.51.4-1.1-1.3-1.3-1.61.2-1.4-0.7-1.31.51.31.3-1.21.21.31.11.51.41.4
Delay discount hyperbolic model param0.10.10.4-0.30.10.10.00.2-0.30.4-0.40.1-0.2-0.0-0.1-0.00.1-0.0-0.60.0-0.4-0.4
Intermittent access intake day 1-15 change0.10.31.0-1.00.60.40.40.4-0.40.6-0.10.6-0.8-0.5-0.40.6-0.6-0.2-0.6-0.6-0.4-0.4
Intermittent access intake escalation0.10.31.0-1.00.60.30.30.6-0.40.8-0.10.6-0.8-0.5-0.40.6-0.6-0.2-0.5-0.6-0.7-0.7
Intermittent access intake escalation 20.20.30.9-0.90.50.40.40.5-0.40.70.20.5-0.7-0.6-0.50.6-0.6-0.1-0.2-0.6-0.5-0.5
Intermitt. access day 1 inactive lever presses0.11.11.7-0.81.21.11.11.2-1.20.91.01.0-1.0-1.1-1.11.0-1.0-1.0-1.3-1.2-0.9-0.9
Intermitt. access day 15 inactive lever presses1.26.710.4-2.02.42.92.82.5-2.52.43.22.6-2.3-2.7-2.72.4-2.3-2.9-2.9-2.6-2.4-2.4
Intermitt. access escalation Index0.20.52.21.5-0.4-0.6-0.6-0.20.5-0.4-0.8-0.70.80.90.5-0.90.90.70.90.5-0.1-0.1
Intermittent access day 1 total infusions0.30.82.9-0.11.11.41.30.9-1.00.11.70.8-0.4-0.7-1.10.6-0.6-1.1-1.3-0.6-0.2-0.2
Intermittent access day 15 total infusions0.51.22.0-0.61.41.41.31.2-1.10.91.31.1-0.9-0.9-1.20.9-0.8-1.0-0.9-0.9-1.1-1.1
Intermittent access terminal intake (last 3 days)0.20.31.10.10.80.90.90.5-0.5-0.01.00.5-0.3-0.3-0.60.3-0.2-0.3-0.8-0.4-0.1-0.1
Intermittent access total infusions0.60.71.6-0.31.11.21.20.8-0.90.11.20.8-0.6-0.6-0.90.7-0.6-0.8-1.3-0.6-0.0-0.0
Intermittent access day 1 locomotion1.32.33.8-1.11.82.01.91.5-1.71.31.91.5-1.3-1.5-1.71.3-1.3-1.3-1.3-1.4-1.4-1.4
Intermittent access day 15 total locomotion0.52.13.4-1.11.91.81.81.3-1.71.31.71.5-1.3-1.4-1.61.4-1.3-1.0-1.1-1.4-1.3-1.3
Intermittent access total locomotion1.41.72.9-1.01.71.61.51.1-1.61.21.41.3-1.2-1.2-1.51.2-1.1-0.8-1.0-1.2-1.2-1.2
Intermittent access standard deviation0.52.45.2-1.41.61.81.71.5-1.21.12.01.6-1.5-1.5-1.51.5-1.4-2.0-2.3-1.6-0.8-0.8
Left kidney weight0.00.40.80.5-0.6-0.6-0.7-0.80.5-0.5-0.6-0.70.70.50.5-0.70.70.9-0.30.80.60.6
Right kidney weight0.00.10.40.5-0.2-0.1-0.2-0.50.1-0.4-0.0-0.30.50.30.3-0.40.50.5-0.10.60.40.4
Cocaine induced anxiety0.10.41.00.6-0.7-0.6-0.6-0.60.7-0.5-0.3-0.60.70.50.7-0.60.60.60.81.00.30.3
Post-drug Anxiety0.60.71.61.3-1.0-0.4-0.5-0.81.0-0.70.6-0.91.20.30.8-1.01.10.60.81.10.40.4
Baseline Anxiety0.40.71.8-0.60.61.00.90.8-0.61.01.40.7-0.6-1.0-0.80.6-0.5-1.0-1.0-0.8-1.1-1.1
Tail length0.31.53.11.6-1.1-0.7-0.7-0.91.4-1.31.1-1.31.40.81.2-1.31.41.41.81.01.01.0
Length with tail1.25.110.53.2-2.1-1.8-1.8-2.12.3-2.6-0.3-2.42.72.12.1-2.52.52.12.82.02.02.0
Length without tail0.63.45.42.3-1.9-1.8-1.8-2.01.7-1.9-1.6-1.92.21.91.7-1.91.91.31.81.91.61.6
Times rat made contact with spout0.30.30.50.2-0.4-0.6-0.6-0.40.6-0.6-0.6-0.50.40.50.6-0.40.40.70.60.60.70.7
Lifetime Intake0.91.12.4-0.31.41.51.41.1-1.20.51.51.0-0.7-0.8-1.20.8-0.7-1.2-1.6-0.9-0.6-0.6
Liver weight, left3.15.38.12.8-2.2-2.0-2.0-2.32.3-2.8-1.2-2.32.62.52.3-2.62.62.11.12.22.52.5
Liver weight, right3.86.69.93.1-2.8-2.1-2.2-2.52.9-2.8-0.9-2.73.02.52.7-2.82.92.22.62.62.42.4
Locomotor activity0.71.12.50.7-1.4-0.6-0.7-0.91.6-1.00.4-1.11.20.41.3-0.90.91.30.91.11.21.2
Locomotor testing distance0.20.62.00.4-1.10.0-0.1-0.41.3-0.51.4-0.70.9-0.20.8-0.50.60.61.10.90.60.6
Locomotor testing rearing0.10.20.8-0.4-0.60.30.20.30.80.60.9-0.10.1-0.60.30.00.0-0.10.30.4-0.6-0.6
Locomotion in novel chamber0.60.81.4-1.21.00.70.80.9-1.10.90.31.0-1.0-0.7-0.91.1-1.1-1.10.3-0.8-0.8-0.8
Locomotion in novel chamber post-restriction1.64.78.91.6-2.0-2.1-2.0-2.52.3-2.7-1.7-1.91.82.12.2-1.81.71.82.22.13.03.0
Fecal boli incidents, locomotor time 10.10.30.9-0.3-0.6-0.6-0.7-0.60.4-0.6-0.4-0.40.20.60.7-0.50.40.7-0.50.40.90.9
Change in fecal boli incidents, locomotor task0.60.63.50.9-0.6-0.8-0.7-0.61.0-0.3-1.0-0.70.60.50.7-0.60.50.51.90.50.00.0
Time >=10cm from walls, locomotor time 10.50.72.8-1.70.40.30.20.4-0.41.6-0.60.5-0.7-0.6-0.30.5-0.60.30.50.2-1.5-1.5
Bouts of movement, locomotor time 12.32.94.5-1.72.01.51.61.5-2.12.00.71.8-1.8-1.6-1.71.7-1.8-1.8-1.0-1.7-2.0-2.0
Total resting periods, locomotor time 12.83.24.6-1.82.01.51.61.7-2.12.10.81.9-1.8-1.6-1.81.8-1.8-1.8-1.0-1.8-2.1-2.1
Rest time, locomotor task time 10.40.71.1-1.00.80.60.70.8-0.70.90.20.9-1.1-0.7-0.70.9-0.9-1.00.2-1.0-0.8-0.8
Distance moved, locomotor task time 10.20.50.90.9-0.7-0.4-0.5-0.60.6-0.80.0-0.70.90.50.6-0.70.70.80.00.90.70.7
Vertical activity count, locomotor time 10.42.74.21.1-1.9-1.7-1.8-1.61.6-1.7-1.5-1.71.51.71.9-1.71.62.00.51.61.71.7
Time >=10cm from walls, locomotor time 20.20.52.1-1.50.1-0.3-0.40.1-0.11.3-0.90.2-0.7-0.20.10.2-0.20.8-0.7-0.2-1.1-1.1
Bouts of movement, locomotor time 20.10.31.0-0.60.40.50.50.7-0.0-0.00.60.5-0.8-0.4-0.40.5-0.5-0.7-1.0-0.90.30.3
Total resting periods, locomotor time 20.10.30.8-0.70.50.60.50.7-0.10.10.50.6-0.8-0.4-0.50.6-0.6-0.7-0.9-0.90.20.2
Rest time, locomotor task time 20.61.01.7-1.01.01.11.10.9-1.00.91.21.1-1.1-1.1-1.11.1-1.1-1.3-0.0-0.9-0.8-0.8
Distance moved, locomotor task time 20.20.21.20.7-0.3-0.3-0.3-0.20.2-0.50.0-0.40.50.40.3-0.50.50.3-1.10.30.40.4
Vertical activity count, locomotor time 20.30.71.30.5-1.1-0.9-1.0-0.80.9-0.7-0.5-1.00.90.91.1-1.11.11.1-0.30.90.60.6
Light reinforcement 10.20.91.71.0-1.0-0.7-0.7-1.01.3-1.00.2-1.01.20.61.0-0.91.00.80.91.01.01.0
Light reinforcement 20.00.10.30.4-0.2-0.0-0.0-0.20.1-0.50.4-0.30.30.10.1-0.30.30.20.30.10.50.5
Bone: marrow area0.10.30.6-0.30.80.40.50.5-0.50.40.60.5-0.4-0.5-0.60.5-0.5-0.50.0-0.6-0.7-0.7
Bone: maximum diameter0.20.40.8-0.90.80.50.50.7-0.50.70.30.7-0.7-0.7-0.50.8-0.8-0.6-0.2-0.6-0.6-0.6
Bone: maximum force0.91.84.2-1.61.21.61.51.3-1.01.32.11.3-1.2-1.6-1.21.4-1.4-1.0-1.2-0.9-0.9-0.9
Bone: maximum moment0.91.83.7-1.51.31.51.51.3-1.01.31.91.4-1.2-1.6-1.21.4-1.4-1.0-1.2-1.0-1.0-1.0
Mean time between licks in bursts0.00.10.3-0.30.10.40.30.2-0.10.40.20.2-0.2-0.2-0.20.2-0.1-0.3-0.5-0.1-0.4-0.4
Mean num. licks in bursts0.30.83.00.8-0.5-0.4-0.4-0.80.3-1.5-0.3-0.60.70.80.4-0.60.70.90.60.51.71.7
Cd content in liver0.00.00.10.20.1-0.1-0.1-0.20.3-0.2-0.0-0.10.20.10.2-0.00.0-0.20.40.10.10.1
Co content in liver0.10.20.3-0.50.40.40.40.5-0.40.30.10.5-0.5-0.4-0.30.6-0.6-0.4-0.3-0.4-0.1-0.1
Cu content in liver2.93.54.7-1.41.92.02.01.9-1.81.82.11.9-1.8-1.9-1.91.9-1.8-2.2-1.3-2.0-1.8-1.8
Fe content in liver0.91.12.51.6-0.9-1.0-0.9-0.91.1-0.9-0.6-1.11.31.00.9-1.21.20.81.61.00.30.3
K content in liver0.10.10.40.30.0-0.3-0.20.00.1-0.2-0.7-0.10.10.50.2-0.10.1-0.2-0.60.00.20.2
Mg content in liver0.20.30.7-0.60.50.30.30.6-0.50.5-0.10.5-0.6-0.3-0.40.5-0.5-0.7-0.9-0.6-0.5-0.5
Mn content in liver0.60.73.5-0.50.80.70.80.8-0.70.50.50.8-0.7-0.5-0.80.8-0.8-1.1-1.9-0.8-0.4-0.4
Na content in liver0.91.01.61.1-1.2-1.2-1.2-0.90.9-0.8-0.9-1.11.21.11.0-1.21.20.90.31.30.60.6
Rb content in liver0.10.10.4-0.50.10.20.20.10.00.10.50.3-0.4-0.2-0.10.3-0.3-0.3-0.7-0.30.10.1
Se content in liver2.53.05.0-1.41.72.01.91.7-1.71.32.21.7-1.5-1.7-1.81.6-1.6-2.1-2.2-1.7-1.2-1.2
Sr content in liver0.00.00.10.30.00.00.0-0.3-0.0-0.20.4-0.00.10.0-0.1-0.10.10.0-0.20.00.20.2
Zn content in liver0.30.41.10.6-0.6-0.5-0.5-0.60.5-1.0-0.2-0.50.50.70.6-0.60.60.50.20.41.01.0
Bone: minimum diameter0.20.51.7-0.40.80.90.90.7-0.60.21.30.7-0.5-0.7-0.70.6-0.6-0.9-0.4-0.6-0.3-0.3
Time in familiar zone, hab. session 10.10.10.5-0.20.20.20.30.2-0.20.40.70.2-0.2-0.4-0.40.3-0.3-0.30.1-0.3-0.4-0.4
Time in novel zone, hab. session 10.20.20.50.1-0.5-0.4-0.5-0.20.5-0.4-0.7-0.40.40.50.4-0.40.40.6-0.10.60.50.5
Total zone transitions, hab. session 10.10.10.3-0.20.20.30.30.4-0.10.50.50.3-0.3-0.4-0.30.2-0.2-0.2-0.1-0.4-0.6-0.6
Total locomotion distance, hab. session 10.10.20.7-0.30.10.30.30.40.10.60.80.3-0.2-0.5-0.30.2-0.2-0.3-0.5-0.2-0.6-0.6
Locomotion velocity, hab. session 10.60.81.6-0.60.80.90.90.9-0.51.01.30.8-0.8-1.0-0.70.8-0.8-1.0-0.9-0.9-1.1-1.1
Time in familiar zone, hab. session 20.20.20.50.10.60.30.40.3-0.70.40.00.4-0.4-0.3-0.60.4-0.4-0.6-0.4-0.7-0.5-0.5
Time in novel zone, hab. session 20.10.10.8-0.4-0.20.20.10.10.3-0.00.90.00.0-0.20.20.1-0.00.10.10.20.20.2
Total zone transitions, hab. session 20.00.00.10.0-0.10.10.10.00.1-0.10.3-0.00.00.1-0.0-0.10.20.10.30.00.10.1
Total locomotion distance, hab. session 20.40.61.1-0.70.60.80.80.8-0.40.91.10.7-0.7-0.8-0.70.7-0.7-0.8-0.6-0.5-0.8-0.8
Locomotion velocity, hab. session 20.40.60.9-0.80.60.80.70.8-0.40.90.90.7-0.7-0.8-0.70.7-0.7-0.7-0.8-0.5-0.9-0.9
Novel to familiar place preference ratio1.31.63.30.6-1.3-1.3-1.3-1.51.2-1.4-1.2-1.21.01.41.4-1.11.11.40.31.21.81.8
Novelty place preference2.32.95.41.0-1.8-1.7-1.8-1.91.7-1.9-1.6-1.61.41.81.8-1.51.51.80.71.62.32.3
Time in novel zone, NPP test2.53.05.51.1-1.8-1.7-1.8-2.01.7-1.9-1.5-1.71.51.81.9-1.61.51.80.81.62.32.3
Total zone transitions, NPP test0.10.10.8-0.20.20.40.40.4-0.10.30.90.2-0.3-0.4-0.30.2-0.1-0.20.1-0.4-0.4-0.4
Total locomotion distance, NPP test1.01.42.9-1.10.91.21.21.3-0.81.31.71.1-1.0-1.4-1.11.1-1.1-1.2-1.0-0.9-1.3-1.3
Locomotion velocity, NPP test1.01.52.6-1.30.91.21.21.4-0.81.41.61.2-1.1-1.4-1.11.2-1.2-1.2-1.1-1.0-1.3-1.3
Intraocular pressure0.61.02.7-1.30.81.01.00.7-1.20.81.71.0-1.0-1.4-1.11.1-1.2-0.8-0.5-0.6-0.4-0.4
Delta distance traveled before/after self-admin0.70.71.60.3-1.0-0.7-0.9-1.01.0-0.3-1.0-0.90.90.71.0-1.01.01.20.31.20.30.3
Delta ambulatory time before/after self-admin0.91.63.00.9-1.5-1.3-1.4-1.31.5-0.4-1.4-1.41.41.11.4-1.51.51.50.81.70.10.1
Parametrial fat weight5.613.318.14.0-3.6-3.2-3.3-3.83.6-4.3-1.9-3.83.83.63.7-3.93.93.73.63.43.93.9
Pavlov. Cond. lever latency0.00.00.3-0.2-0.1-0.2-0.20.00.20.3-0.5-0.10.00.00.0-0.00.00.0-0.10.2-0.3-0.3
Pavlov. Cond. magazine entry latency0.20.21.30.8-0.2-0.6-0.6-0.40.2-0.4-1.1-0.40.40.70.4-0.40.40.3-0.10.30.20.2
Pavlov. Cond. change in total contacts0.30.30.8-0.20.60.70.70.6-0.50.40.90.6-0.5-0.5-0.60.5-0.5-0.8-0.5-0.7-0.5-0.5
Pavlov. Cond. index score0.00.00.20.50.1-0.1-0.1-0.1-0.1-0.2-0.1-0.00.10.20.1-0.10.10.0-0.2-0.10.10.1
Pavlov. Cond. latency score0.00.00.20.5-0.0-0.2-0.1-0.20.0-0.3-0.2-0.10.20.30.2-0.20.20.1-0.10.00.30.3
Pavlov. Cond. lever contacts0.00.00.20.4-0.00.10.1-0.1-0.0-0.30.5-0.10.10.10.1-0.10.10.10.1-0.10.40.4
Pavlov. Cond. magazine entry number0.10.10.3-0.50.10.40.30.1-0.20.10.60.2-0.2-0.3-0.20.2-0.2-0.10.1-0.1-0.0-0.0
Pavlov. Cond. intertrial magazine entries0.50.61.7-0.80.60.90.80.9-0.61.01.30.7-0.5-1.0-0.70.8-0.7-0.70.2-0.3-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.40.20.00.00.0-0.1-0.0-0.00.1-0.00.10.00.0-0.0-0.1-0.3-0.2-0.0-0.0
Pavlov. Cond. response bias0.10.10.50.7-0.2-0.3-0.3-0.30.3-0.3-0.3-0.30.30.40.3-0.30.30.20.20.10.20.2
Pavlov. Cond. lever latency0.50.71.91.4-0.5-0.6-0.6-1.00.4-1.2-0.7-0.70.71.10.5-0.80.80.50.90.31.01.0
Pavlov. Cond. magazine entry latency0.30.40.90.4-0.8-0.6-0.6-0.51.0-0.6-0.5-0.70.70.40.8-0.60.60.70.70.80.70.7
Pavlov. Cond. change in total contacts0.10.31.1-1.00.30.20.20.4-0.30.9-0.20.4-0.4-0.6-0.20.5-0.6-0.2-0.6-0.2-0.7-0.7
Pavlov. Cond. index score0.20.31.0-1.00.20.40.40.6-0.10.70.60.4-0.4-0.8-0.20.6-0.6-0.2-0.5-0.1-0.5-0.5
Pavlov. Cond. latency score0.20.41.4-1.20.30.50.40.7-0.20.80.60.5-0.5-0.9-0.30.7-0.7-0.3-0.5-0.2-0.5-0.5
Pavlov. Cond. lever contacts0.20.20.9-1.00.10.30.20.6-0.10.80.50.3-0.3-0.7-0.20.5-0.5-0.2-0.5-0.1-0.6-0.6
Pavlov. Cond. magazine entry number0.40.50.9-0.40.80.60.60.6-0.90.70.20.7-0.8-0.4-0.80.6-0.6-0.8-0.9-0.8-0.8-0.8
Pavlov. Cond. intertrial magazine entries0.00.10.30.2-0.4-0.4-0.4-0.20.30.0-0.2-0.30.30.20.3-0.40.40.50.50.4-0.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.5-0.7-0.10.20.10.30.10.40.40.1-0.1-0.6-0.00.3-0.30.0-0.40.1-0.2-0.2
Pavlov. Cond. response bias0.10.10.3-0.5-0.10.00.00.30.30.50.20.10.0-0.50.10.2-0.2-0.1-0.30.2-0.4-0.4
Time in closed arm before self-admin1.93.24.41.8-2.0-1.5-1.6-2.02.0-1.8-0.4-2.02.01.61.9-1.92.02.11.51.91.71.7
Time in closed arm after self-admin0.50.61.30.3-1.0-0.6-0.7-0.80.9-0.90.0-0.70.60.60.9-0.60.60.90.90.61.11.1
Time in open arm before self-admin1.21.42.4-1.21.41.11.21.3-1.31.00.51.3-1.4-1.1-1.21.5-1.5-1.50.1-1.3-0.8-0.8
Time in open arm after self-admin0.40.41.4-0.20.80.20.30.5-0.60.8-0.40.5-0.5-0.4-0.50.4-0.4-0.8-1.2-0.5-1.0-1.0
Bone: periosteal estimation0.51.12.1-1.11.21.11.11.1-0.91.01.51.1-1.0-1.2-1.01.1-1.1-1.1-0.6-1.0-0.9-0.9
Bone: periosteal perimeter0.00.00.1-0.20.0-0.1-0.1-0.10.3-0.10.00.00.0-0.10.20.1-0.10.20.00.10.30.3
Bone: post-yield work0.00.10.70.3-0.00.20.20.1-0.1-0.20.8-0.00.2-0.1-0.1-0.00.1-0.1-0.20.20.10.1
Progressive ratio test 1 active lever presses1.11.93.6-0.81.61.81.81.3-1.40.81.91.4-1.1-1.3-1.51.3-1.2-1.9-1.3-1.2-0.9-0.9
Progressive ratio test 1 breakpoint1.32.24.1-0.81.71.91.91.4-1.50.92.01.5-1.2-1.4-1.61.3-1.3-2.0-1.4-1.3-1.0-1.0
Progressive ratio test 1 inactive lever presses2.15.57.2-2.22.32.72.62.5-2.12.32.52.4-2.3-2.5-2.32.3-2.3-2.4-2.2-2.3-2.2-2.2
Progressive ratio test 2 active lever presses2.43.45.3-1.72.32.12.11.9-2.01.61.71.9-1.9-1.8-1.91.8-1.8-1.6-1.5-2.0-1.5-1.5
Progressive ratio test 2 breakpoint2.83.65.6-1.72.42.22.12.0-2.11.71.72.0-2.0-1.8-2.01.9-1.9-1.7-1.6-2.0-1.6-1.6
Progressive ratio test 2 inactive lever presses0.51.62.6-1.51.41.61.51.2-1.30.81.51.4-1.5-1.3-1.21.4-1.3-0.8-0.9-1.5-0.5-0.5
Incentive Sensitization - Responses0.51.42.9-1.21.71.31.31.4-1.41.10.61.3-1.4-1.0-1.31.2-1.2-0.5-0.5-1.4-1.0-1.0
Incentive Sensitization - Breakpoint0.61.32.6-1.21.61.31.31.4-1.41.00.71.2-1.3-1.0-1.31.1-1.1-0.5-0.5-1.4-1.0-1.0
Sum of active levers in priming session hrs 5-60.80.82.11.4-0.6-0.9-0.8-0.90.7-0.7-0.7-0.91.00.90.7-1.01.11.01.20.60.30.3
Progressive ratio1.02.85.6-1.61.92.02.01.5-1.71.32.41.8-1.6-1.9-1.81.7-1.7-1.4-1.5-1.6-1.0-1.0
Food seeking constrained by brief footshock0.10.21.2-0.10.20.50.40.5-0.20.41.10.2-0.1-0.5-0.30.2-0.1-0.1-0.5-0.3-0.4-0.4
Seeking ratio, punishment vs. effort0.71.52.41.1-1.6-1.5-1.5-1.01.3-0.8-1.4-1.41.31.31.4-1.31.31.11.11.30.50.5
Retroperitoneal fat weight2.19.411.63.4-3.3-2.9-2.9-3.13.2-3.3-1.9-3.33.32.93.2-3.23.22.93.02.93.03.0
Reaction time number correct0.62.03.01.2-1.2-1.5-1.5-1.51.4-1.4-1.3-1.41.41.31.5-1.21.11.71.71.41.51.5
Reaction time mean minus median0.00.30.80.9-0.4-0.4-0.4-0.60.3-0.7-0.6-0.50.60.60.3-0.50.50.10.60.40.50.5
Reaction time mean minus median AUC0.31.83.41.6-1.3-1.4-1.4-1.31.4-1.3-1.8-1.41.41.61.3-1.41.41.00.81.21.11.1
Reaction time num false alarms1.52.63.9-2.01.41.41.41.5-1.61.81.71.6-1.7-1.7-1.41.7-1.7-1.5-2.0-1.4-1.4-1.4
Reaction time num false alarms AUC1.84.15.6-2.31.81.91.92.0-2.12.32.12.0-2.1-2.2-1.82.1-2.1-1.9-2.4-1.8-1.9-1.9
Reaction time trials correct on left0.62.03.01.2-1.2-1.5-1.5-1.51.4-1.4-1.3-1.41.41.31.5-1.21.11.71.71.41.51.5
Reaction time trials on left0.62.23.11.2-1.3-1.6-1.5-1.51.4-1.4-1.4-1.51.41.41.5-1.21.11.71.81.51.61.6
Reaction time mean0.71.42.21.5-1.4-1.0-1.0-1.21.2-1.4-0.9-1.31.31.21.2-1.21.30.81.11.11.21.2
Reaction time mean AUC0.51.32.01.4-1.2-1.0-1.0-1.21.1-1.4-1.0-1.21.21.21.1-1.11.20.70.91.01.21.2
Median of all reaction times0.91.42.01.4-1.4-1.0-1.0-1.21.2-1.3-0.8-1.31.31.11.3-1.21.30.91.01.11.21.2
Reaction time omissions2.03.27.01.5-1.9-2.1-2.0-1.81.7-1.7-2.6-1.81.62.01.7-1.81.71.51.01.71.61.6
Reaction time false alarm rate4.46.18.3-2.52.22.42.42.4-2.52.62.62.5-2.5-2.6-2.32.4-2.4-2.4-2.9-2.3-2.4-2.4
Reaction time premature initiation rate0.71.22.91.7-0.7-1.3-1.2-1.10.7-1.0-1.5-1.11.31.20.8-1.21.21.00.20.90.50.5
Reaction time premature initiations0.82.44.12.0-1.2-1.9-1.7-1.71.3-1.4-2.0-1.61.81.61.3-1.51.51.61.01.51.21.2
Std. dev. reaction times0.20.51.01.0-0.7-0.7-0.6-0.80.7-0.8-0.9-0.70.80.80.6-0.70.70.20.60.60.70.7
Reaction time trials completed0.62.23.11.2-1.3-1.6-1.5-1.51.4-1.4-1.4-1.51.41.41.5-1.21.11.71.81.51.61.6
Reaction time trials AUC0.62.13.31.1-1.3-1.6-1.5-1.51.4-1.4-1.4-1.41.41.31.5-1.21.11.71.81.51.51.5
Run reversals in cocaine runway, females0.00.00.2-0.10.10.10.10.4-0.10.0-0.00.2-0.2-0.1-0.20.2-0.2-0.5-0.4-0.1-0.2-0.2
Run reversals in cocaine runway, males0.70.73.80.8-0.50.00.0-0.70.6-1.31.1-0.40.50.30.4-0.30.40.31.90.41.51.5
Latency to leave start box in cocaine runway0.50.71.5-0.11.00.91.00.9-1.10.01.20.8-0.5-0.7-1.00.9-0.8-1.2-0.1-0.8-0.1-0.1
Latency to leave start box in cocaine runway, F0.10.21.1-0.10.40.40.50.4-0.5-0.11.10.3-0.2-0.4-0.40.3-0.3-0.60.3-0.10.10.1
Latency to leave start box in cocaine runway, M1.11.12.3-0.01.41.11.31.1-1.40.20.81.1-0.8-0.7-1.31.1-1.1-1.5-0.7-1.5-0.3-0.3
Std. dev. time between licks in bursts0.51.02.1-1.40.91.11.01.3-1.00.90.71.1-1.2-0.9-1.01.1-1.1-0.9-1.1-1.0-0.6-0.6
Total sessions with >9 infusions0.40.51.50.61.01.01.00.7-0.70.11.10.5-0.1-0.3-0.80.3-0.2-1.2-0.8-0.5-0.5-0.5
Short access day 1 total inactive lever presses0.00.10.50.30.10.10.0-0.2-0.0-0.2-0.1-0.10.20.30.1-0.30.40.7-0.60.20.10.1
Short access day 10 total inactive lever presses0.10.40.9-0.60.70.30.30.7-0.70.9-0.10.6-0.7-0.5-0.50.6-0.7-0.0-0.1-0.9-1.0-1.0
Short access day 1 total infusions0.51.02.20.21.51.21.21.2-1.40.71.00.9-0.6-0.6-1.30.7-0.6-1.0-0.8-1.0-1.2-1.2
Short access day 10 total infusions0.20.33.60.20.50.50.50.4-0.3-0.40.50.3-0.10.1-0.40.1-0.0-0.7-1.9-0.30.40.4
Short access total infusions1.11.53.8-0.31.41.61.51.3-1.30.71.71.1-0.8-0.9-1.40.9-0.8-1.5-1.9-1.0-0.9-0.9
Short access day 1 locomotion1.22.03.3-0.51.81.41.51.5-1.61.41.11.4-1.1-1.0-1.51.2-1.2-1.5-1.5-1.4-1.7-1.7
Short access day 10 total locomotion0.93.56.4-1.72.51.81.91.8-2.21.81.21.9-1.9-1.7-2.01.9-1.9-1.5-2.0-2.1-1.6-1.6
Short access total locomotion3.24.87.5-1.52.72.32.42.2-2.52.01.82.2-2.0-1.9-2.42.1-2.0-2.2-2.5-2.3-2.1-2.1
One hour access (0.3 mA shock)1.41.72.7-1.21.61.61.61.2-1.30.81.21.4-1.4-1.2-1.41.3-1.2-1.2-1.5-1.6-0.7-0.7
Compulsive drug intake0.20.41.71.3-0.1-0.6-0.5-0.4-0.1-0.1-0.6-0.50.60.60.1-0.60.60.61.2-0.4-0.5-0.5
One hour access (shock baseline)0.41.02.3-1.31.01.41.30.8-0.60.41.01.1-1.1-0.9-0.81.0-1.0-1.2-1.5-0.70.00.0
Social response proportion2.02.53.41.8-1.6-1.4-1.4-1.81.5-1.8-1.1-1.61.71.61.5-1.61.61.61.31.41.81.8
Social responses0.50.71.51.0-1.0-0.3-0.4-1.01.0-0.70.8-0.91.10.30.8-0.90.90.61.20.90.60.6
Social time0.30.51.11.0-0.6-0.3-0.3-0.80.7-1.00.4-0.70.80.60.6-0.70.80.60.50.50.90.9
Soleus weight1.85.46.62.5-2.2-2.3-2.3-2.12.1-2.3-2.2-2.42.52.62.3-2.52.52.42.32.52.02.0
Bone: stiffness0.20.30.60.7-0.5-0.2-0.2-0.60.6-0.80.4-0.50.70.40.5-0.60.60.60.40.60.70.7
Tibialis anterior weight0.62.14.12.0-1.3-1.4-1.3-1.61.2-1.4-0.9-1.51.71.61.3-1.61.61.22.01.51.01.0
Time to tail flick, vehicle, before self-admin0.00.00.20.10.10.0-0.0-0.1-0.10.0-0.10.00.20.0-0.1-0.10.10.20.50.2-0.2-0.2
Time to tail flick, vehicle, after self-admin0.71.42.01.1-1.4-1.3-1.3-1.31.4-1.0-0.5-1.31.21.11.4-1.21.21.41.11.20.90.9
Time to tail flick, test, before self-admin0.30.30.6-0.2-0.8-0.5-0.6-0.70.8-0.4-0.5-0.50.50.20.7-0.40.40.60.20.70.60.6
Time to tail flick, test, after self-admin0.30.40.8-0.40.80.50.60.7-0.80.40.00.7-0.5-0.5-0.70.7-0.8-0.90.1-0.5-0.4-0.4
Delta time to tail flick, vehicle, before/after SA0.40.40.80.2-0.8-0.8-0.8-0.60.8-0.3-0.4-0.70.50.50.9-0.50.50.8-0.00.70.30.3
Delta time to tail flick, test, before/after SA1.62.03.2-0.81.81.41.51.6-1.71.21.11.5-1.4-1.2-1.71.5-1.5-1.7-0.6-1.6-1.4-1.4
Tibia length0.00.10.3-0.40.00.20.20.20.10.00.60.2-0.3-0.20.10.2-0.2-0.1-0.6-0.00.20.2
Ambulatory time before self-admin0.10.31.4-0.10.50.80.80.3-0.5-0.31.20.5-0.4-0.5-0.60.6-0.6-0.60.1-0.80.40.4
Ambulatory time after self-admin0.81.32.01.1-1.3-0.9-1.0-1.31.4-1.0-0.5-1.31.41.01.2-1.21.31.41.01.30.90.9
Bone: tissue strength0.20.20.3-0.50.40.40.40.4-0.60.50.30.4-0.4-0.5-0.50.5-0.5-0.2-0.5-0.5-0.4-0.4
Total heroin consumption0.80.92.41.5-0.8-0.5-0.5-0.80.9-1.2-0.2-0.91.30.90.7-1.11.10.71.20.81.01.0
Bone: trabecular number2.54.76.02.5-2.3-2.3-2.3-2.42.4-2.1-1.8-2.22.32.22.2-2.32.32.01.42.01.81.8
Bone: trabecular spacing0.81.11.8-1.21.21.11.11.3-1.31.10.41.1-1.1-0.9-1.11.2-1.2-1.0-0.9-0.9-0.9-0.9
Bone: trabecular thickness0.20.30.60.6-0.7-0.5-0.5-0.60.8-0.40.2-0.60.80.30.5-0.60.60.60.40.60.30.3
Bone: trabecular tissue density0.30.51.1-1.00.50.70.70.8-0.41.00.70.6-0.6-1.0-0.70.7-0.7-0.5-0.5-0.5-0.9-0.9
Water consumed over 24 hours0.20.40.70.8-0.4-0.9-0.8-0.50.6-0.9-0.8-0.60.50.80.7-0.60.60.60.30.50.80.8
Number of responses in last shaping day1.11.44.2-0.71.00.70.81.4-1.31.7-0.31.0-1.1-0.8-1.10.9-0.9-0.9-0.6-1.2-2.0-2.0