Hub : Genes

Retreg1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Retreg1 0.3 0.39 8.9e-05 0.08 0.06 0.06 0.1 3.0e-04 1.7e-03 2.1e-03 5.3e-05
2 IL gene expression Retreg1 0.22 0.18 1.4e-03 0.06 0.08 0.08 0.07 1.8e-02 5.8e-03 4.9e-03 7.7e-03
3 OFC gene expression Retreg1 0.18 0.16 2.9e-03 0.07 0.1 0.06 0.08 9.0e-03 2.6e-03 1.4e-02 5.5e-03
4 Brain gene expression Retreg1 0.33 0.21 0.0e+00 0.18 0.19 0.18 0.19 5.5e-17 4.6e-17 6.4e-17 4.8e-17
5 PL gene expression Retreg1 0.15 0.13 1.1e-13 0.11 0.12 0.12 0.11 2.9e-12 9.1e-13 1.1e-12 1.6e-12
6 Liver intron excision ratio chr2_76391957_76465158 0.03 0.03 5.3e-03 0.01 0.01 0.01 0.01 1.8e-02 1.2e-02 1.5e-02 2.3e-02
7 Liver alternative TSS XM_006232084.4 0.04 0.04 7.7e-04 0.02 0.02 0.01 0.02 4.5e-03 2.7e-03 8.0e-03 3.6e-03
8 Liver alternative TSS XM_006232084.4 0.03 0.03 1.6e-03 0.02 0.02 0.02 0.02 5.8e-03 4.0e-03 5.2e-03 5.2e-03
9 Liver isoform ratio NM_001034912.1 0.04 0.04 7.2e-04 0.02 0.02 0.01 0.01 6.1e-03 6.0e-03 1.1e-02 7.1e-03
10 Liver isoform ratio XM_006232084.4 0.04 0.04 6.9e-04 0.02 0.02 0.02 0.02 5.3e-03 2.5e-03 3.5e-03 3.9e-03
11 Liver isoform ratio XM_039103027.1 0.03 0.03 2.2e-03 0.01 0.01 0 0.01 2.1e-02 5.4e-02 1.7e-01 4.9e-02
12 Liver alternative TSS NM_001034912.1 0.04 0.04 3.1e-04 0.02 0.01 0.01 0.01 3.9e-03 8.8e-03 1.5e-02 8.4e-03
13 Liver alternative TSS XM_039103027.1 0.04 0.04 4.9e-04 0.01 0.01 0.01 0.01 1.1e-02 2.8e-02 2.0e-02 2.8e-02
14 Liver intron excision ratio chr2_76442158_76465158 0.03 0.03 4.8e-03 0.01 0.01 0.01 0.01 1.8e-02 2.2e-02 2.9e-02 2.4e-02
15 Adipose alternative TSS XM_039103027.1 0.04 0.04 6.8e-04 0.02 0.02 0.02 0.02 9.3e-04 1.3e-03 2.8e-03 9.4e-04
16 Adipose gene expression Retreg1 0.03 0.03 3.4e-03 0.02 0.02 0.02 0.02 4.9e-03 5.3e-03 6.2e-03 5.2e-03
17 Adipose isoform ratio XM_039103026.1 0.03 0.03 6.9e-03 0.01 0.01 0.01 0.01 1.2e-02 1.5e-02 7.9e-03 1.7e-02
18 Adipose alternative TSS XM_006232084.4 0.03 0.03 5.4e-03 0.02 0.01 0.02 0.02 2.0e-03 6.8e-03 1.6e-03 2.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density2.44.15.42.3-1.72.02.02.02.0-2.0-2.02.0-2.02.2-2.22.22.2-2.0-2.02.10.0
Area under the delay curve5.05.36.0-2.42.3-2.3-2.3-2.3-2.32.32.3-2.32.3-2.42.4-2.4-2.42.52.5-2.30.0
BMI with tail0.41.41.61.2-1.21.21.21.21.2-1.2-1.21.2-1.21.3-1.31.31.3-1.1-1.11.20.0
BMI without tail0.00.10.10.3-0.20.30.30.30.3-0.3-0.30.3-0.30.3-0.30.30.3-0.4-0.40.30.0
Body weight0.00.00.1-0.10.3-0.2-0.2-0.2-0.20.20.2-0.20.2-0.00.0-0.0-0.00.40.4-0.20.0
Weight adjusted by age0.00.00.2-0.20.4-0.3-0.3-0.3-0.30.30.3-0.30.3-0.10.1-0.1-0.10.00.0-0.10.0
Bone surface4.27.59.53.1-2.62.82.82.82.8-2.8-2.82.8-2.82.9-2.92.92.9-2.7-2.72.80.0
Bone volume5.59.411.83.4-2.93.13.13.13.1-3.1-3.13.1-3.13.2-3.23.23.2-3.1-3.13.20.0
Breakpoint value in progressive ratio session1.01.11.6-1.11.0-1.0-1.0-1.0-1.01.01.0-1.01.0-1.21.2-1.2-1.21.31.3-1.10.0
Number of licking bursts0.20.20.3-0.60.2-0.4-0.4-0.4-0.40.40.4-0.40.4-0.50.5-0.5-0.50.50.5-0.50.0
Context. condit. distance diff. score1.21.42.0-1.31.4-1.2-1.2-1.3-1.21.21.2-1.21.2-1.21.2-1.2-1.21.11.1-1.20.0
Locomotion velocity, session 11.21.31.5-1.21.1-1.2-1.2-1.2-1.21.21.2-1.21.2-1.21.2-1.2-1.21.21.2-1.10.0
Locomotion distance, session 10.30.40.5-0.70.5-0.7-0.7-0.7-0.70.70.7-0.70.7-0.60.6-0.6-0.60.60.6-0.60.0
Locomotion velocity, session 20.40.40.60.7-0.80.70.70.70.7-0.7-0.70.7-0.70.6-0.60.60.6-0.5-0.50.60.0
Locomotion distance, session 20.20.30.4-0.60.3-0.6-0.6-0.6-0.60.60.6-0.60.6-0.60.6-0.6-0.60.60.6-0.60.0
Locomotion velocity, session 30.10.10.2-0.40.5-0.4-0.4-0.4-0.40.40.4-0.40.4-0.40.4-0.4-0.40.30.3-0.30.0
Locomotion distance, session 30.30.41.1-0.61.0-0.7-0.7-0.7-0.70.70.7-0.70.7-0.50.5-0.5-0.50.40.4-0.50.0
Stereotopy head waving bouts, day 30.10.10.4-0.40.6-0.4-0.4-0.4-0.40.40.4-0.40.4-0.30.3-0.3-0.30.30.3-0.30.0
Stereotopy head waving duration, day 30.10.10.10.3-0.20.30.30.30.3-0.3-0.30.3-0.30.3-0.30.30.3-0.2-0.20.30.0
Locomotion velocity, session 70.00.00.10.10.10.10.10.10.1-0.1-0.10.1-0.10.3-0.30.30.3-0.3-0.30.30.0
Locomotion distance, session 70.00.00.00.10.1-0.0-0.1-0.1-0.00.00.0-0.00.00.2-0.20.20.2-0.1-0.10.10.0
Stereotopy head waving bouts, day 70.80.91.7-1.01.3-0.9-0.9-0.9-0.90.90.9-0.90.9-1.01.0-1.0-1.00.80.8-0.90.0
Stereotopy head waving duration, day 70.40.51.2-0.81.1-0.7-0.7-0.7-0.70.70.7-0.70.7-0.80.8-0.8-0.80.70.7-0.70.0
Locomotion velocity, session 80.50.50.7-0.80.8-0.8-0.8-0.8-0.80.80.8-0.80.8-0.80.8-0.8-0.80.70.7-0.70.0
Locomotion distance, session 81.31.92.2-1.51.4-1.4-1.5-1.4-1.41.41.4-1.41.4-1.41.4-1.4-1.41.31.3-1.30.0
Degree of sensitization distance0.60.61.20.8-1.10.80.80.80.8-0.8-0.80.8-0.80.8-0.80.80.8-0.6-0.60.80.0
Degree of sensitization stereotypy2.02.23.2-1.61.8-1.5-1.5-1.5-1.51.51.5-1.51.5-1.51.5-1.5-1.51.41.4-1.50.0
Conditioned locomotion2.12.42.91.7-1.41.61.61.61.6-1.6-1.61.6-1.61.7-1.71.71.7-1.7-1.71.70.0
Cocaine response after cond. corrected0.40.40.50.7-0.60.70.70.70.7-0.7-0.70.7-0.70.7-0.70.70.7-0.6-0.60.60.0
Cocaine response after cond. not corrected1.11.21.51.2-1.21.21.21.21.2-1.2-1.21.2-1.21.1-1.11.11.1-1.1-1.11.10.0
Cocaine response before conditioning0.50.61.00.8-1.00.80.80.80.8-0.8-0.80.8-0.80.8-0.80.80.8-0.8-0.80.80.0
Saline control response2.12.83.31.8-1.71.71.71.71.7-1.7-1.71.7-1.71.6-1.61.61.6-1.8-1.81.70.0
Bone: connectivity density1.11.72.51.6-1.11.31.31.31.3-1.3-1.31.3-1.31.5-1.51.51.5-1.3-1.31.40.0
Bone: cortical apparent density0.30.40.8-0.70.9-0.7-0.7-0.7-0.70.70.7-0.70.7-0.60.6-0.6-0.60.50.5-0.60.0
Bone: cortical area1.42.12.81.6-1.71.51.51.51.5-1.5-1.51.5-1.51.4-1.41.41.4-1.5-1.51.50.0
Bone: cortical porosity0.70.81.1-1.00.8-0.9-0.9-0.9-0.90.90.9-0.90.9-0.90.9-0.9-0.91.01.0-1.00.0
Bone: cortical porosity1.41.51.8-1.31.3-1.2-1.2-1.2-1.21.21.2-1.21.2-1.31.3-1.3-1.31.41.4-1.30.0
Bone: cortical thickness0.10.10.2-0.40.2-0.4-0.4-0.4-0.40.40.4-0.40.4-0.40.4-0.4-0.40.40.4-0.40.0
Bone: cortical thickness0.00.00.10.2-0.20.10.00.10.1-0.1-0.10.1-0.10.3-0.30.30.3-0.3-0.30.20.0
Bone: cortical tissue density0.30.40.7-0.60.9-0.7-0.7-0.7-0.70.70.7-0.70.7-0.60.6-0.6-0.60.50.5-0.60.0
Condit. Reinf. active minus inactive responses0.00.00.0-0.10.0-0.1-0.1-0.1-0.10.10.1-0.10.1-0.10.1-0.1-0.10.00.0-0.10.0
Condit. Reinf. active-inactive response ratio0.91.01.31.0-1.01.01.01.01.0-1.0-1.01.0-1.01.0-1.01.01.0-1.1-1.11.00.0
Condit. Reinf. active responses0.10.10.2-0.40.2-0.4-0.4-0.4-0.40.40.4-0.40.4-0.40.4-0.4-0.40.30.3-0.30.0
Condit. Reinf. inactive responses0.40.50.6-0.70.5-0.7-0.7-0.7-0.70.70.7-0.70.7-0.80.8-0.8-0.80.70.7-0.70.0
Incentive salience index mean0.20.20.40.5-0.70.50.50.50.5-0.5-0.50.5-0.50.5-0.50.50.5-0.5-0.50.50.0
Condit. Reinf. lever presses0.91.31.91.2-1.41.21.21.21.2-1.2-1.21.2-1.21.1-1.11.11.1-1.1-1.11.10.0
Condit. Reinf. active minus inactive responses0.10.10.20.3-0.40.40.40.40.4-0.4-0.40.4-0.40.2-0.20.20.2-0.2-0.20.30.0
Condit. Reinf. active-inactive response ratio0.10.10.2-0.20.0-0.2-0.2-0.2-0.20.20.2-0.20.2-0.30.3-0.3-0.30.50.5-0.30.0
Condit. Reinf. active responses0.20.30.50.5-0.70.60.60.60.6-0.6-0.60.6-0.60.4-0.40.40.4-0.6-0.60.50.0
Condit. Reinf. inactive responses0.20.30.50.5-0.60.50.50.50.5-0.5-0.50.5-0.50.4-0.40.40.4-0.7-0.70.60.0
Condit. Reinf. lever presses1.82.43.01.7-1.71.71.71.71.6-1.6-1.61.6-1.61.5-1.51.51.5-1.6-1.61.60.0
Condit. Reinf. lever reinforcers received0.20.30.50.6-0.70.60.60.60.6-0.6-0.60.6-0.60.4-0.40.40.4-0.6-0.60.60.0
Conditioned reinforcement - actives0.10.10.10.3-0.30.20.20.20.2-0.2-0.20.2-0.20.3-0.30.30.3-0.3-0.30.20.0
Conditioned reinforcement - inactives0.20.30.5-0.50.4-0.5-0.5-0.5-0.50.50.5-0.50.5-0.50.5-0.5-0.50.70.7-0.60.0
Conditioned locomotion2.63.13.6-1.91.8-1.8-1.8-1.8-1.81.81.8-1.81.8-1.81.8-1.8-1.81.91.9-1.80.0
Patch foraging indifference point 0 sec0.20.40.70.8-0.50.70.70.70.7-0.7-0.70.7-0.70.6-0.60.60.6-0.6-0.60.60.0
Patch foraging indifference point AUC1.41.62.6-1.31.0-1.2-1.2-1.2-1.21.21.2-1.21.2-1.41.4-1.4-1.41.61.6-1.40.0
Delay disc. indifference point, 0s delay0.10.10.2-0.50.4-0.4-0.4-0.4-0.40.40.4-0.40.4-0.30.3-0.3-0.30.20.2-0.20.0
Delay disc. indifference point, 16s delay2.12.22.5-1.51.4-1.5-1.5-1.5-1.51.51.5-1.51.5-1.61.6-1.6-1.61.61.6-1.50.0
Delay disc. indifference point, 2s delay1.92.12.6-1.61.4-1.4-1.4-1.4-1.41.41.4-1.41.4-1.51.5-1.5-1.51.61.6-1.50.0
Delay disc. indifference point, 24s delay1.41.31.8-1.11.0-1.1-1.1-1.1-1.11.11.1-1.11.1-1.21.2-1.2-1.21.41.4-1.20.0
Delay disc. indifference point, 4s delay7.27.69.1-3.02.8-2.8-2.8-2.8-2.82.82.8-2.82.8-2.92.9-2.9-2.93.03.0-2.80.0
Delay disc. indifference point, 8s delay1.71.72.1-1.41.3-1.3-1.3-1.3-1.31.31.3-1.31.3-1.31.3-1.3-1.31.41.4-1.30.0
Indifference point function ln k1.21.62.11.4-1.11.21.21.21.3-1.3-1.31.3-1.31.4-1.41.41.4-1.5-1.51.30.0
Indifference point function log k1.21.62.11.4-1.11.21.21.21.3-1.3-1.31.3-1.31.4-1.41.41.4-1.5-1.51.30.0
Patch foraging total patch changes 0 sec0.40.71.11.0-0.70.90.90.90.8-0.8-0.80.8-0.80.8-0.80.80.8-0.8-0.80.80.0
Patch foraging total patch changes 12 sec0.30.40.70.9-0.60.60.60.60.6-0.6-0.60.6-0.60.6-0.60.60.6-0.5-0.50.60.0
Patch foraging total patch changes 18 sec0.10.20.3-0.20.2-0.3-0.2-0.2-0.30.30.3-0.30.3-0.50.5-0.5-0.50.60.6-0.50.0
Patch foraging total patch changes 24 sec0.00.00.10.3-0.20.20.30.30.2-0.2-0.20.2-0.2-0.10.1-0.1-0.10.20.2-0.00.0
Patch foraging total patch changes 6 sec0.10.10.20.4-0.30.30.30.30.3-0.3-0.30.3-0.30.3-0.30.30.3-0.3-0.30.30.0
Patch foraging time to switch 0 sec0.30.40.60.7-0.60.60.60.60.7-0.6-0.60.6-0.60.7-0.70.70.7-0.8-0.80.70.0
Patch foraging water rate 0 sec1.42.22.8-1.61.5-1.5-1.5-1.5-1.51.51.5-1.51.5-1.51.5-1.5-1.51.71.7-1.60.0
Patch foraging water rate 12 sec0.81.21.4-1.21.1-1.1-1.0-1.1-1.11.11.1-1.11.1-1.21.2-1.2-1.21.21.2-1.10.0
Patch foraging water rate 18 sec0.00.00.1-0.1-0.00.10.10.10.0-0.1-0.10.1-0.1-0.00.0-0.0-0.00.30.3-0.10.0
Patch foraging water rate 24 sec0.30.40.70.6-0.40.60.60.60.6-0.6-0.60.6-0.60.8-0.80.80.8-0.7-0.70.70.0
Patch foraging water rate 6 sec0.10.10.20.3-0.30.40.40.40.4-0.4-0.40.4-0.40.4-0.40.40.4-0.2-0.20.20.0
Seeking ratio, delayed vs. immediate footshock0.10.20.3-0.40.5-0.4-0.4-0.4-0.40.40.4-0.40.4-0.40.4-0.4-0.40.30.3-0.30.0
Distance traveled before self-admin5.35.77.0-2.62.7-2.5-2.5-2.5-2.52.52.5-2.52.5-2.32.3-2.3-2.32.32.3-2.40.0
Distance traveled after self-admin7.58.39.5-3.13.0-2.9-2.9-2.9-2.92.92.9-2.92.9-3.03.0-3.0-3.03.03.0-3.00.0
Extensor digitorum longus weight1.14.46.1-2.22.2-2.1-2.1-2.1-2.12.12.1-2.12.1-2.12.1-2.1-2.12.52.5-2.20.0
Bone: elastic displacement0.30.40.8-0.70.9-0.7-0.7-0.7-0.70.70.7-0.70.7-0.50.5-0.5-0.50.50.5-0.60.0
Bone: elastic work2.32.93.51.9-1.51.71.71.71.7-1.7-1.71.7-1.71.8-1.81.81.8-1.9-1.91.80.0
Bone: endosteal estimation6.414.016.24.0-4.03.93.93.93.9-3.9-3.93.9-3.93.7-3.73.73.7-3.8-3.83.80.0
Bone: endosteal perimeter1.63.34.22.1-2.02.02.02.01.9-1.9-1.91.9-1.91.7-1.71.71.7-1.8-1.81.80.0
Epididymis fat weight3.17.28.5-2.92.9-2.8-2.8-2.8-2.82.82.8-2.82.8-2.72.7-2.7-2.72.72.7-2.70.0
Delta time in closed arm before/after self-admin0.20.10.20.4-0.40.40.40.40.4-0.4-0.40.4-0.40.4-0.40.40.4-0.4-0.40.40.0
Delta time in open arm before/after self-admin0.10.10.2-0.10.0-0.2-0.2-0.1-0.20.20.2-0.20.2-0.30.3-0.3-0.30.40.4-0.30.0
Diff in mean of infusions in LGA sessions0.70.81.1-1.00.9-0.9-0.9-0.9-0.90.90.9-0.90.9-0.80.8-0.8-0.81.01.0-0.90.0
Delay discount exponential model param5.05.36.22.4-2.32.32.32.32.3-2.3-2.32.3-2.32.4-2.42.42.4-2.5-2.52.30.0
Extinction: sum of active levers before priming0.00.00.1-0.20.1-0.1-0.1-0.1-0.10.10.1-0.10.1-0.30.3-0.3-0.3-0.1-0.1-0.10.0
Active lever presses in extinction session 62.92.83.5-1.81.6-1.6-1.7-1.6-1.71.71.7-1.71.7-1.81.8-1.8-1.81.91.9-1.80.0
Bone: final force3.96.37.72.8-2.62.62.62.62.6-2.6-2.62.6-2.62.6-2.62.62.6-2.4-2.42.60.0
Bone: final moment5.18.310.13.2-3.03.03.03.03.0-3.0-3.03.0-3.02.9-2.92.92.9-2.8-2.82.90.0
Food consumed during 24 hour testing period0.20.30.4-0.50.5-0.5-0.5-0.5-0.50.50.5-0.50.5-0.50.5-0.5-0.50.70.7-0.60.0
Glucose0.10.20.20.5-0.40.40.40.40.4-0.4-0.40.4-0.40.5-0.50.50.5-0.5-0.50.50.0
Heart weight0.20.30.50.7-0.50.60.60.60.6-0.6-0.60.6-0.60.5-0.50.50.5-0.6-0.60.60.0
Delay discount hyperbolic model param5.76.07.02.6-2.52.52.52.52.5-2.5-2.52.5-2.52.5-2.52.52.5-2.7-2.72.50.0
Intermittent access intake day 1-15 change0.00.00.00.1-0.00.10.10.00.1-0.1-0.10.1-0.10.1-0.10.10.1-0.2-0.20.10.0
Intermittent access intake escalation0.00.00.00.1-0.10.10.10.10.1-0.1-0.10.1-0.10.2-0.20.20.2-0.1-0.10.10.0
Intermittent access intake escalation 20.20.20.30.5-0.60.50.50.50.5-0.5-0.50.5-0.50.5-0.50.50.5-0.5-0.50.50.0
Intermitt. access day 1 inactive lever presses0.10.10.10.3-0.30.20.20.20.2-0.2-0.20.2-0.20.3-0.30.30.3-0.2-0.20.30.0
Intermitt. access day 15 inactive lever presses0.70.70.9-0.90.9-0.9-0.9-0.9-0.90.90.9-0.90.9-0.90.9-0.9-0.90.80.8-0.80.0
Intermitt. access escalation Index2.92.53.01.7-1.61.61.61.61.6-1.6-1.61.6-1.61.7-1.71.71.7-1.7-1.71.60.0
Intermittent access day 1 total infusions3.23.74.3-2.11.9-1.9-1.9-1.9-1.91.91.9-1.91.9-2.12.1-2.1-2.12.02.0-2.00.0
Intermittent access day 15 total infusions1.41.51.8-1.31.3-1.3-1.3-1.3-1.31.31.3-1.31.3-1.31.3-1.3-1.31.31.3-1.30.0
Intermittent access terminal intake (last 3 days)2.22.42.8-1.71.6-1.6-1.6-1.6-1.61.61.6-1.61.6-1.61.6-1.6-1.61.61.6-1.60.0
Intermittent access total infusions3.53.94.5-2.11.9-2.0-2.0-2.0-2.02.02.0-2.02.0-2.12.1-2.1-2.12.12.1-2.10.0
Intermittent access day 1 locomotion6.77.08.2-2.92.7-2.7-2.6-2.6-2.72.72.7-2.72.7-2.82.8-2.8-2.82.82.8-2.80.0
Intermittent access day 15 total locomotion4.85.16.0-2.52.3-2.3-2.3-2.3-2.32.32.3-2.32.3-2.32.3-2.3-2.32.42.4-2.40.0
Intermittent access total locomotion7.48.49.9-3.22.9-2.9-2.9-2.9-2.92.92.9-2.92.9-3.03.0-3.0-3.03.13.1-3.00.0
Intermittent access standard deviation0.10.10.2-0.40.3-0.3-0.3-0.3-0.30.30.3-0.30.3-0.30.3-0.3-0.30.20.2-0.30.0
Left kidney weight0.10.30.4-0.60.6-0.6-0.6-0.6-0.50.50.5-0.50.5-0.40.4-0.4-0.40.40.4-0.50.0
Right kidney weight0.10.40.6-0.80.7-0.7-0.7-0.7-0.70.70.7-0.70.7-0.60.6-0.6-0.60.60.6-0.70.0
Cocaine induced anxiety0.10.10.2-0.30.3-0.2-0.2-0.2-0.30.30.3-0.30.3-0.40.4-0.4-0.40.50.5-0.40.0
Post-drug Anxiety0.50.50.6-0.80.7-0.7-0.7-0.7-0.70.70.7-0.70.7-0.80.8-0.8-0.80.70.7-0.70.0
Baseline Anxiety0.20.30.4-0.60.6-0.6-0.6-0.6-0.60.60.6-0.60.6-0.40.4-0.4-0.40.30.3-0.40.0
Tail length0.00.00.10.00.2-0.1-0.1-0.1-0.10.10.1-0.10.1-0.10.1-0.1-0.1-0.0-0.0-0.10.0
Length with tail0.00.10.2-0.40.4-0.3-0.3-0.3-0.30.30.3-0.30.3-0.30.3-0.3-0.30.40.4-0.40.0
Length without tail0.10.20.30.6-0.50.50.50.50.5-0.5-0.50.5-0.50.5-0.50.50.5-0.3-0.30.40.0
Times rat made contact with spout0.70.81.01.0-0.90.90.90.90.9-0.9-0.90.9-0.91.0-1.01.01.0-1.0-1.00.90.0
Lifetime Intake2.22.42.9-1.71.5-1.6-1.6-1.6-1.61.61.6-1.61.6-1.61.6-1.6-1.61.61.6-1.60.0
Liver weight, left0.10.20.2-0.40.5-0.4-0.4-0.4-0.40.40.4-0.40.4-0.40.4-0.4-0.40.40.4-0.40.0
Liver weight, right0.10.10.2-0.40.4-0.3-0.3-0.3-0.30.30.3-0.30.3-0.30.3-0.3-0.30.30.3-0.30.0
Locomotor activity0.50.71.1-0.91.0-0.9-0.9-0.9-0.90.90.9-0.90.9-0.90.9-0.9-0.90.60.6-0.80.0
Locomotor testing distance0.10.20.2-0.40.5-0.5-0.5-0.5-0.50.50.5-0.50.5-0.30.3-0.3-0.30.20.2-0.40.0
Locomotor testing rearing0.30.50.8-0.80.9-0.8-0.8-0.9-0.80.80.8-0.80.8-0.50.5-0.5-0.50.40.4-0.60.0
Locomotion in novel chamber0.10.20.3-0.40.6-0.5-0.5-0.5-0.40.40.4-0.40.4-0.30.3-0.3-0.30.50.5-0.40.0
Locomotion in novel chamber post-restriction0.10.10.20.2-0.40.30.30.30.3-0.3-0.30.3-0.30.2-0.20.20.2-0.2-0.20.20.0
Fecal boli incidents, locomotor time 10.20.20.3-0.50.5-0.5-0.5-0.5-0.50.50.5-0.50.5-0.50.5-0.5-0.50.30.3-0.40.0
Change in fecal boli incidents, locomotor task0.90.91.1-1.00.9-0.9-0.9-0.9-0.90.90.9-0.90.9-1.01.0-1.0-1.01.01.0-0.90.0
Time >=10cm from walls, locomotor time 10.10.10.20.4-0.50.40.40.40.4-0.4-0.40.4-0.40.3-0.30.30.3-0.2-0.20.30.0
Bouts of movement, locomotor time 10.10.10.2-0.30.4-0.4-0.4-0.4-0.40.40.4-0.40.4-0.20.2-0.2-0.20.20.2-0.20.0
Total resting periods, locomotor time 10.00.00.1-0.10.3-0.3-0.3-0.3-0.20.20.2-0.20.2-0.00.0-0.0-0.00.00.0-0.10.0
Rest time, locomotor task time 10.40.50.90.5-0.40.50.50.50.6-0.6-0.60.6-0.60.8-0.80.80.8-0.9-0.90.80.0
Distance moved, locomotor task time 10.00.00.1-0.0-0.0-0.00.00.0-0.00.00.0-0.00.0-0.10.1-0.1-0.10.30.3-0.20.0
Vertical activity count, locomotor time 10.00.00.10.3-0.30.30.30.30.2-0.2-0.20.2-0.20.1-0.10.10.10.20.20.00.0
Time >=10cm from walls, locomotor time 20.90.91.31.1-1.11.11.11.11.0-1.0-1.01.0-1.00.9-0.90.90.9-0.9-0.91.00.0
Bouts of movement, locomotor time 20.20.20.3-0.40.6-0.5-0.5-0.5-0.50.50.5-0.50.5-0.20.2-0.2-0.20.40.4-0.40.0
Total resting periods, locomotor time 20.10.10.2-0.30.4-0.4-0.4-0.4-0.40.40.4-0.40.4-0.10.1-0.1-0.10.20.2-0.30.0
Rest time, locomotor task time 20.00.00.1-0.10.2-0.2-0.2-0.2-0.10.10.1-0.10.1-0.00.0-0.0-0.0-0.2-0.20.00.0
Distance moved, locomotor task time 20.10.10.3-0.40.4-0.3-0.3-0.3-0.30.30.3-0.30.3-0.30.3-0.3-0.30.60.6-0.40.0
Vertical activity count, locomotor time 20.20.20.6-0.40.3-0.3-0.3-0.3-0.30.30.3-0.30.3-0.40.4-0.4-0.40.80.8-0.50.0
Light reinforcement 10.00.10.2-0.20.5-0.3-0.3-0.3-0.30.30.3-0.30.3-0.20.2-0.2-0.2-0.1-0.1-0.20.0
Light reinforcement 20.10.20.30.4-0.40.30.30.30.3-0.3-0.30.3-0.30.5-0.50.50.5-0.5-0.50.40.0
Bone: marrow area6.413.916.24.0-4.03.93.93.93.9-3.9-3.93.9-3.93.7-3.73.73.7-3.8-3.83.80.0
Bone: maximum diameter1.01.82.81.4-1.71.41.41.41.4-1.4-1.41.4-1.41.3-1.31.31.3-1.3-1.31.30.0
Bone: maximum force3.96.78.32.9-2.72.72.72.72.7-2.7-2.72.7-2.72.6-2.62.62.6-2.5-2.52.70.0
Bone: maximum moment5.18.810.73.3-3.13.13.13.13.1-3.1-3.13.1-3.13.0-3.03.03.0-2.9-2.93.00.0
Mean time between licks in bursts0.50.71.00.8-1.00.80.80.80.8-0.8-0.80.8-0.80.9-0.90.90.9-1.0-1.00.90.0
Mean num. licks in bursts1.31.62.31.5-1.01.31.31.31.3-1.3-1.31.3-1.31.3-1.31.31.3-1.3-1.31.30.0
Cd content in liver2.93.23.9-1.91.7-1.8-1.8-1.8-1.81.81.8-1.81.8-1.91.9-1.9-1.92.02.0-1.80.0
Co content in liver0.00.00.00.10.10.10.10.10.1-0.1-0.10.1-0.10.1-0.10.10.10.00.00.00.0
Cu content in liver0.10.10.20.3-0.50.30.30.30.3-0.3-0.30.3-0.30.3-0.30.30.3-0.2-0.20.30.0
Fe content in liver0.70.81.60.9-1.30.90.90.90.9-0.9-0.90.9-0.90.9-0.90.90.9-1.0-1.00.90.0
K content in liver0.70.70.9-0.90.8-0.8-0.8-0.8-0.90.80.8-0.80.8-0.90.9-0.9-0.90.90.9-0.90.0
Mg content in liver0.30.30.4-0.60.5-0.5-0.5-0.5-0.50.50.5-0.50.5-0.60.6-0.6-0.60.60.6-0.60.0
Mn content in liver2.42.73.3-1.81.7-1.7-1.7-1.7-1.71.71.7-1.71.7-1.71.7-1.7-1.71.71.7-1.70.0
Na content in liver0.00.00.0-0.1-0.2-0.1-0.1-0.1-0.10.10.1-0.10.1-0.10.1-0.1-0.10.00.0-0.10.0
Rb content in liver0.00.00.1-0.20.1-0.2-0.2-0.2-0.20.20.2-0.20.2-0.20.2-0.2-0.20.20.2-0.20.0
Se content in liver0.00.00.1-0.2-0.1-0.1-0.1-0.1-0.10.10.1-0.10.1-0.20.2-0.2-0.20.20.2-0.20.0
Sr content in liver0.70.60.80.9-0.80.80.80.80.8-0.8-0.80.8-0.80.8-0.80.80.8-0.7-0.70.80.0
Zn content in liver1.71.92.3-1.51.4-1.4-1.4-1.4-1.41.41.4-1.41.4-1.41.4-1.4-1.41.41.4-1.40.0
Bone: minimum diameter2.95.47.02.5-2.72.52.52.52.4-2.4-2.42.4-2.42.3-2.32.32.3-2.2-2.22.40.0
Time in familiar zone, hab. session 11.71.62.11.3-1.51.31.31.31.3-1.3-1.31.3-1.31.2-1.21.21.2-1.4-1.41.30.0
Time in novel zone, hab. session 13.23.14.6-1.92.1-1.8-1.8-1.8-1.81.81.8-1.81.8-1.81.8-1.8-1.81.71.7-1.80.0
Total zone transitions, hab. session 12.02.83.4-1.91.6-1.7-1.7-1.8-1.71.71.7-1.71.7-1.81.8-1.8-1.81.61.6-1.70.0
Total locomotion distance, hab. session 11.82.63.1-1.81.6-1.7-1.7-1.7-1.71.71.7-1.71.7-1.61.6-1.6-1.61.51.5-1.60.0
Locomotion velocity, hab. session 11.92.73.3-1.81.6-1.8-1.8-1.8-1.71.71.7-1.71.7-1.61.6-1.6-1.61.71.7-1.70.0
Time in familiar zone, hab. session 20.10.10.10.2-0.20.20.20.20.2-0.2-0.20.2-0.20.3-0.30.30.3-0.3-0.30.20.0
Time in novel zone, hab. session 20.10.10.10.3-0.40.30.30.30.3-0.3-0.30.3-0.30.3-0.30.30.3-0.2-0.20.30.0
Total zone transitions, hab. session 25.97.69.2-3.02.6-2.9-2.9-2.9-2.92.92.9-2.92.9-2.82.8-2.8-2.82.82.8-2.80.0
Total locomotion distance, hab. session 21.92.63.1-1.81.6-1.7-1.7-1.7-1.71.71.7-1.71.7-1.61.6-1.6-1.61.71.7-1.60.0
Locomotion velocity, hab. session 21.62.12.6-1.61.4-1.6-1.6-1.6-1.51.51.5-1.51.5-1.41.4-1.4-1.41.51.5-1.40.0
Novel to familiar place preference ratio0.00.00.00.10.00.10.10.10.1-0.1-0.10.1-0.10.2-0.20.20.2-0.0-0.00.10.0
Novelty place preference0.00.00.10.2-0.10.20.20.20.2-0.2-0.20.2-0.20.2-0.20.20.2-0.2-0.20.20.0
Time in novel zone, NPP test0.10.10.10.4-0.20.30.30.30.3-0.3-0.30.3-0.30.4-0.40.40.4-0.3-0.30.30.0
Total zone transitions, NPP test2.63.74.6-2.11.8-2.0-2.0-2.0-2.02.02.0-2.02.0-2.02.0-2.0-2.02.02.0-1.90.0
Total locomotion distance, NPP test0.81.11.4-1.20.9-1.1-1.1-1.1-1.11.11.1-1.11.1-1.01.0-1.0-1.01.11.1-1.00.0
Locomotion velocity, NPP test0.71.01.3-1.10.9-1.1-1.1-1.1-1.01.01.0-1.01.0-0.90.9-0.9-0.91.11.1-1.00.0
Intraocular pressure0.00.00.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.10.1-0.00.0-0.0-0.0-0.3-0.30.10.0
Delta distance traveled before/after self-admin0.10.10.20.3-0.40.30.30.30.3-0.3-0.30.3-0.30.1-0.10.10.10.20.20.10.0
Delta ambulatory time before/after self-admin0.00.10.20.3-0.40.30.30.30.3-0.3-0.30.3-0.30.1-0.10.10.10.00.00.10.0
Parametrial fat weight0.20.40.7-0.80.8-0.6-0.6-0.6-0.60.60.6-0.60.6-0.60.6-0.6-0.60.70.7-0.70.0
Pavlov. Cond. lever latency1.51.92.9-1.41.7-1.4-1.4-1.5-1.41.41.4-1.41.4-1.31.3-1.3-1.31.31.3-1.40.0
Pavlov. Cond. magazine entry latency0.40.50.70.8-0.80.80.80.80.8-0.8-0.80.8-0.80.7-0.70.70.7-0.6-0.60.70.0
Pavlov. Cond. change in total contacts0.91.01.31.1-1.11.01.01.01.0-1.0-1.01.0-1.00.9-0.90.90.9-1.0-1.01.00.0
Pavlov. Cond. index score0.60.71.20.9-1.10.90.91.00.9-0.9-0.90.9-0.90.8-0.80.80.8-0.7-0.70.80.0
Pavlov. Cond. latency score0.81.01.61.1-1.31.11.11.11.1-1.1-1.11.1-1.10.9-0.90.90.9-0.9-0.91.00.0
Pavlov. Cond. lever contacts2.32.73.61.7-1.91.71.71.71.7-1.7-1.71.7-1.71.6-1.61.61.6-1.6-1.61.60.0
Pavlov. Cond. magazine entry number0.70.81.1-1.11.0-1.0-1.0-1.0-1.01.01.0-1.01.0-0.90.9-0.9-0.90.80.8-0.90.0
Pavlov. Cond. intertrial magazine entries1.41.72.1-1.41.4-1.4-1.4-1.4-1.41.41.4-1.41.4-1.31.3-1.3-1.31.31.3-1.30.0
Pavlov. Cond. lever-magazine prob. diff.0.91.11.61.1-1.21.11.11.11.1-1.1-1.11.1-1.11.0-1.01.01.0-0.9-0.91.00.0
Pavlov. Cond. response bias1.41.72.01.4-1.41.31.31.31.3-1.3-1.31.3-1.31.3-1.31.31.3-1.3-1.31.30.0
Pavlov. Cond. lever latency0.00.00.2-0.10.4-0.2-0.2-0.2-0.20.20.2-0.20.2-0.00.0-0.0-0.00.10.1-0.10.0
Pavlov. Cond. magazine entry latency0.00.00.10.2-0.30.20.20.20.2-0.2-0.20.2-0.20.2-0.20.20.2-0.2-0.20.10.0
Pavlov. Cond. change in total contacts0.10.10.2-0.40.2-0.3-0.3-0.3-0.30.30.3-0.30.3-0.40.4-0.4-0.40.30.3-0.40.0
Pavlov. Cond. index score0.00.10.20.2-0.50.30.30.30.3-0.3-0.30.3-0.30.1-0.10.10.1-0.3-0.30.20.0
Pavlov. Cond. latency score0.10.10.30.3-0.60.40.40.40.3-0.3-0.30.3-0.30.2-0.20.20.2-0.4-0.40.30.0
Pavlov. Cond. lever contacts0.00.00.10.1-0.30.20.20.20.1-0.1-0.10.1-0.2-0.00.0-0.0-0.0-0.1-0.10.10.0
Pavlov. Cond. magazine entry number0.00.00.00.00.10.00.00.00.0-0.0-0.00.0-0.00.1-0.10.10.1-0.2-0.20.10.0
Pavlov. Cond. intertrial magazine entries1.51.92.31.5-1.31.41.41.41.4-1.4-1.41.4-1.41.4-1.41.41.4-1.5-1.51.50.0
Pavlov. Cond. lever-magazine prob. diff.0.00.00.10.1-0.30.10.10.10.1-0.1-0.10.1-0.10.0-0.00.00.0-0.1-0.10.10.0
Pavlov. Cond. response bias0.00.00.0-0.0-0.20.00.00.10.0-0.0-0.00.0-0.0-0.10.1-0.1-0.10.00.0-0.00.0
Time in closed arm before self-admin1.51.72.51.5-1.61.41.41.41.4-1.4-1.41.4-1.41.2-1.21.21.2-1.1-1.11.20.0
Time in closed arm after self-admin1.31.31.81.3-1.31.11.11.11.2-1.2-1.21.2-1.21.1-1.11.11.1-1.3-1.31.20.0
Time in open arm before self-admin2.42.63.6-1.91.8-1.7-1.6-1.7-1.71.71.7-1.71.7-1.61.6-1.6-1.61.71.7-1.70.0
Time in open arm after self-admin1.21.31.6-1.21.3-1.1-1.1-1.1-1.11.11.1-1.11.1-1.21.2-1.2-1.21.21.2-1.20.0
Bone: periosteal estimation5.611.614.13.7-3.83.63.63.63.5-3.5-3.53.5-3.53.3-3.33.33.3-3.4-3.43.40.0
Bone: periosteal perimeter0.61.01.41.2-1.21.11.11.11.1-1.1-1.11.1-1.10.9-0.90.90.9-0.9-0.91.00.0
Bone: post-yield work4.46.08.62.7-2.92.62.72.72.6-2.6-2.62.6-2.62.3-2.32.32.3-2.3-2.32.40.0
Progressive ratio test 1 active lever presses5.76.07.0-2.62.5-2.5-2.4-2.4-2.52.52.5-2.52.5-2.62.6-2.6-2.62.62.6-2.60.0
Progressive ratio test 1 breakpoint5.35.56.5-2.52.4-2.4-2.4-2.3-2.42.42.4-2.42.4-2.52.5-2.5-2.52.52.5-2.50.0
Progressive ratio test 1 inactive lever presses1.92.02.4-1.51.4-1.5-1.5-1.5-1.51.51.5-1.51.5-1.51.5-1.5-1.51.51.5-1.50.0
Progressive ratio test 2 active lever presses2.72.93.4-1.81.7-1.7-1.7-1.7-1.71.71.7-1.71.7-1.81.8-1.8-1.81.91.9-1.80.0
Progressive ratio test 2 breakpoint1.71.92.2-1.51.3-1.4-1.4-1.3-1.41.41.4-1.41.4-1.41.4-1.4-1.41.51.5-1.40.0
Progressive ratio test 2 inactive lever presses2.63.03.6-1.91.8-1.8-1.8-1.8-1.81.81.8-1.81.8-1.81.8-1.8-1.81.81.8-1.80.0
Incentive Sensitization - Responses1.51.51.8-1.31.3-1.2-1.2-1.2-1.31.31.3-1.31.3-1.31.3-1.3-1.31.31.3-1.30.0
Incentive Sensitization - Breakpoint1.31.31.5-1.21.2-1.1-1.1-1.1-1.11.11.1-1.11.1-1.21.2-1.2-1.21.21.2-1.20.0
Sum of active levers in priming session hrs 5-60.30.30.4-0.50.5-0.5-0.5-0.5-0.50.50.5-0.50.5-0.60.6-0.6-0.60.70.7-0.50.0
Progressive ratio0.20.20.40.6-0.60.50.50.50.5-0.5-0.50.5-0.50.5-0.50.50.5-0.4-0.40.60.0
Food seeking constrained by brief footshock2.53.03.81.8-1.91.71.71.71.7-1.7-1.71.7-1.71.8-1.81.81.8-2.0-2.01.90.0
Seeking ratio, punishment vs. effort0.00.00.10.1-0.10.10.10.10.1-0.1-0.10.1-0.10.1-0.10.10.1-0.3-0.30.10.0
Retroperitoneal fat weight0.41.42.2-1.31.5-1.3-1.3-1.3-1.31.31.3-1.31.3-1.21.2-1.2-1.21.01.0-1.20.0
Reaction time number correct1.82.53.11.8-1.31.61.51.51.6-1.6-1.61.6-1.61.8-1.81.81.8-1.7-1.71.70.0
Reaction time mean minus median16.421.727.4-5.24.9-4.8-4.8-4.8-4.84.84.8-4.84.8-4.74.7-4.7-4.74.54.5-4.80.0
Reaction time mean minus median AUC13.417.422.2-4.74.5-4.4-4.4-4.4-4.44.44.4-4.44.4-4.24.2-4.2-4.23.93.9-4.20.0
Reaction time num false alarms0.50.60.80.9-0.80.70.70.70.7-0.7-0.70.7-0.70.9-0.90.90.9-0.9-0.90.90.0
Reaction time num false alarms AUC0.30.40.50.7-0.70.60.60.60.6-0.6-0.60.6-0.60.7-0.70.70.7-0.6-0.60.70.0
Reaction time trials correct on left1.82.53.11.8-1.31.61.51.51.6-1.6-1.61.6-1.61.8-1.81.81.8-1.7-1.71.70.0
Reaction time trials on left1.42.12.61.6-1.21.41.41.41.4-1.4-1.41.4-1.41.6-1.61.61.6-1.6-1.61.50.0
Reaction time mean10.114.216.8-4.14.0-3.9-3.9-3.9-3.93.93.9-3.93.9-3.83.8-3.8-3.83.63.6-3.80.0
Reaction time mean AUC10.413.916.8-4.13.9-3.9-3.9-3.9-3.93.93.9-3.93.9-3.83.8-3.8-3.83.53.5-3.70.0
Median of all reaction times5.47.48.3-2.92.8-2.8-2.8-2.8-2.82.82.8-2.82.8-2.82.8-2.8-2.82.62.6-2.70.0
Reaction time omissions3.85.26.9-2.62.6-2.4-2.4-2.4-2.42.42.4-2.42.4-2.32.3-2.3-2.32.12.1-2.30.0
Reaction time false alarm rate0.10.10.2-0.40.2-0.4-0.4-0.4-0.40.40.4-0.40.4-0.40.4-0.4-0.40.50.5-0.30.0
Reaction time premature initiation rate4.86.47.42.7-2.52.52.52.52.5-2.5-2.52.5-2.52.7-2.72.72.7-2.6-2.62.60.0
Reaction time premature initiations6.79.511.43.3-2.93.03.03.03.1-3.1-3.13.1-3.13.4-3.43.43.4-3.3-3.33.20.0
Std. dev. reaction times12.217.121.2-4.64.4-4.3-4.3-4.3-4.34.34.3-4.34.3-4.24.2-4.2-4.24.04.0-4.20.0
Reaction time trials completed1.42.12.61.6-1.21.41.41.41.4-1.4-1.41.4-1.41.6-1.61.61.6-1.6-1.61.50.0
Reaction time trials AUC1.52.22.71.7-1.21.41.41.41.4-1.4-1.41.4-1.41.7-1.71.71.7-1.6-1.61.50.0
Run reversals in cocaine runway, females0.10.10.3-0.50.6-0.4-0.4-0.4-0.40.40.4-0.40.4-0.30.3-0.3-0.3-0.1-0.1-0.40.0
Run reversals in cocaine runway, males0.80.81.00.9-0.90.80.80.80.9-0.9-0.90.9-0.91.0-1.01.01.0-0.9-0.90.90.0
Latency to leave start box in cocaine runway0.30.40.6-0.60.7-0.6-0.7-0.7-0.60.60.6-0.60.6-0.40.4-0.4-0.40.80.8-0.60.0
Latency to leave start box in cocaine runway, F0.30.40.6-0.60.8-0.7-0.7-0.7-0.70.70.7-0.70.7-0.30.3-0.3-0.30.70.7-0.70.0
Latency to leave start box in cocaine runway, M0.00.00.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.10.1-0.30.3-0.3-0.30.30.3-0.20.0
Std. dev. time between licks in bursts0.00.00.10.1-0.20.10.10.10.1-0.1-0.10.1-0.10.2-0.20.20.2-0.3-0.30.20.0
Total sessions with >9 infusions0.10.10.2-0.30.2-0.3-0.3-0.3-0.30.30.3-0.30.3-0.40.4-0.4-0.40.40.4-0.40.0
Short access day 1 total inactive lever presses1.01.11.4-1.11.1-1.1-1.1-1.1-1.11.11.1-1.11.1-1.01.0-1.0-1.01.21.2-1.10.0
Short access day 10 total inactive lever presses0.00.00.0-0.00.1-0.1-0.1-0.1-0.10.10.1-0.10.1-0.00.0-0.0-0.00.00.00.00.0
Short access day 1 total infusions1.11.11.4-1.11.0-1.1-1.1-1.1-1.11.11.1-1.11.1-1.11.1-1.1-1.11.21.2-1.10.0
Short access day 10 total infusions1.31.41.7-1.31.1-1.2-1.2-1.2-1.21.21.2-1.21.2-1.31.3-1.3-1.31.21.2-1.20.0
Short access total infusions1.82.02.4-1.61.4-1.5-1.5-1.5-1.51.51.5-1.51.5-1.51.5-1.5-1.51.51.5-1.50.0
Short access day 1 locomotion0.50.60.7-0.80.7-0.8-0.8-0.8-0.80.80.8-0.80.8-0.70.7-0.7-0.70.80.8-0.80.0
Short access day 10 total locomotion1.92.12.6-1.61.4-1.4-1.4-1.4-1.41.41.4-1.41.4-1.51.5-1.5-1.51.51.5-1.50.0
Short access total locomotion2.62.73.3-1.81.6-1.6-1.6-1.6-1.71.61.6-1.61.6-1.71.7-1.7-1.71.71.7-1.70.0
One hour access (0.3 mA shock)0.30.30.4-0.60.5-0.6-0.6-0.6-0.60.60.6-0.60.6-0.60.6-0.6-0.60.60.6-0.60.0
Compulsive drug intake0.20.20.3-0.40.5-0.5-0.5-0.5-0.50.50.5-0.50.5-0.30.3-0.3-0.30.30.3-0.40.0
One hour access (shock baseline)0.20.20.3-0.50.4-0.4-0.4-0.4-0.40.40.4-0.40.4-0.60.6-0.6-0.60.60.6-0.50.0
Social response proportion0.50.50.9-0.70.8-0.6-0.6-0.6-0.70.70.7-0.70.7-0.80.8-0.8-0.80.90.9-0.80.0
Social responses0.00.00.1-0.20.0-0.1-0.1-0.1-0.10.10.1-0.10.1-0.30.3-0.3-0.30.30.3-0.20.0
Social time1.62.12.4-1.61.5-1.5-1.5-1.5-1.51.51.5-1.51.5-1.51.5-1.5-1.51.51.5-1.50.0
Soleus weight0.10.30.4-0.60.6-0.5-0.5-0.5-0.60.60.6-0.60.6-0.70.7-0.7-0.70.60.6-0.60.0
Bone: stiffness2.03.13.81.9-1.91.91.91.91.8-1.8-1.81.8-1.81.7-1.71.71.7-1.7-1.71.80.0
Tibialis anterior weight0.10.41.0-0.50.7-0.5-0.5-0.5-0.50.50.5-0.50.5-0.60.6-0.6-0.61.01.0-0.70.0
Time to tail flick, vehicle, before self-admin0.60.71.0-0.91.0-0.9-1.0-1.0-0.90.90.9-0.90.9-0.70.7-0.7-0.70.60.6-0.80.0
Time to tail flick, vehicle, after self-admin0.30.30.4-0.60.6-0.6-0.6-0.6-0.60.60.6-0.60.6-0.50.5-0.5-0.50.70.7-0.60.0
Time to tail flick, test, before self-admin0.60.60.8-0.80.9-0.9-0.9-0.9-0.90.90.9-0.90.9-0.70.7-0.7-0.70.30.3-0.70.0
Time to tail flick, test, after self-admin0.00.00.00.2-0.10.00.00.00.0-0.0-0.00.0-0.00.1-0.10.10.1-0.2-0.20.10.0
Delta time to tail flick, vehicle, before/after SA0.00.00.10.2-0.20.30.30.30.2-0.2-0.20.2-0.20.2-0.20.20.2-0.1-0.10.20.0
Delta time to tail flick, test, before/after SA0.60.50.80.8-0.90.80.80.80.8-0.8-0.80.8-0.80.7-0.70.70.7-0.6-0.60.70.0
Tibia length3.28.910.33.2-3.23.13.13.13.1-3.1-3.13.1-3.13.1-3.13.13.1-3.0-3.03.00.0
Ambulatory time before self-admin5.15.36.7-2.62.5-2.4-2.4-2.4-2.42.42.4-2.42.4-2.22.2-2.2-2.22.32.3-2.30.0
Ambulatory time after self-admin5.86.37.6-2.72.5-2.5-2.5-2.5-2.52.52.5-2.52.5-2.62.6-2.6-2.62.82.8-2.60.0
Bone: tissue strength3.83.74.62.1-1.92.02.12.02.0-2.0-2.02.0-2.02.0-2.02.02.0-1.8-1.81.90.0
Total heroin consumption0.10.10.3-0.3-0.0-0.1-0.1-0.1-0.10.10.1-0.10.1-0.40.4-0.4-0.40.50.5-0.20.0
Bone: trabecular number1.82.93.82.0-1.41.71.61.61.7-1.7-1.71.7-1.71.9-1.91.91.9-1.8-1.81.80.0
Bone: trabecular spacing2.12.73.6-1.91.4-1.7-1.7-1.6-1.71.71.7-1.71.7-1.81.8-1.8-1.81.71.7-1.70.0
Bone: trabecular thickness7.18.510.13.2-2.82.92.92.93.0-3.0-3.03.0-3.03.1-3.13.13.1-3.1-3.13.00.0
Bone: trabecular tissue density5.47.69.4-3.12.8-2.8-2.8-2.8-2.82.82.8-2.82.8-2.92.9-2.9-2.92.82.8-2.80.0
Water consumed over 24 hours1.11.31.91.2-1.41.21.21.21.2-1.2-1.21.2-1.21.1-1.11.11.1-1.1-1.11.10.0
Number of responses in last shaping day0.00.00.0-0.1-0.0-0.1-0.1-0.1-0.10.10.1-0.10.1-0.20.2-0.2-0.20.10.1-0.10.0