Rara

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	IC	isoform ratio	NM_031528.2	0.08	0.06	6.1e-03	0.03	0.03	0	0.02	2.3e-02	1.5e-02	2.2e-01	4.9e-02
2	IC	alternative TSS	NM_031528.2	0.1	0.07	1.5e-03	0.02	0.05	0.03	0.05	4.1e-02	2.6e-03	2.2e-02	4.6e-03
3	IC	mRNA stability	Rara	0.13	0.08	6.1e-05	0.06	0.08	0.07	0.08	2.0e-03	2.9e-04	9.2e-04	4.3e-04
4	IC	gene expression	Rara	0.29	0.18	4.8e-06	0.15	0.14	0.13	0.14	5.7e-07	1.3e-06	5.5e-06	1.6e-06
5	Liver	mRNA stability	Rara	0.09	0.05	2.9e-05	0.04	0.04	0.03	0.04	3.5e-05	2.4e-05	2.7e-04	8.7e-05
6	Liver	intron excision ratio	chr10_84389819_84398920	0.05	0.04	7.4e-05	0.05	0.03	0.03	0.04	1.7e-06	2.9e-04	1.4e-04	6.2e-05
7	Liver	intron excision ratio	chr10_84389819_84401621	0.06	0.04	5.5e-06	0.05	0.03	0.04	0.05	3.8e-06	1.1e-04	1.1e-05	4.4e-06
8	Liver	alternative TSS	NM_031528.2	0.02	0.02	3.0e-03	0.02	0.01	0.02	0.01	3.2e-03	3.6e-02	5.9e-03	9.4e-03
9	Liver	gene expression	Rara	0.03	0.03	8.6e-04	0.01	0.01	0.01	0.01	1.2e-02	1.3e-02	1.7e-02	8.0e-03
10	Brain	mRNA stability	Rara	0.03	0.02	3.1e-03	0.01	0.02	0.02	0.02	2.2e-02	3.2e-03	9.1e-03	1.1e-02
11	OFC	gene expression	Rara	0.21	0.12	4.3e-04	0.1	0.14	0.12	0.13	2.4e-03	3.8e-04	9.4e-04	4.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	2.1	3.9	5.0	1.8	1.8	-1.8	-1.9	-1.9	-2.0	2.2	2.2	1.9	-2.0	2.2
Area under the delay curve	0.3	0.4	0.8	0.6	0.6	-0.7	-0.9	-0.3	-0.5	0.7	0.5	0.6	-0.9	0.8
BMI with tail	2.4	8.3	11.2	-3.3	-3.3	3.3	2.8	2.9	2.7	-2.7	-2.7	-2.6	2.8	-2.4
BMI without tail	0.7	3.7	5.4	-2.3	-2.3	2.3	1.9	1.9	1.5	-1.9	-1.8	-1.8	1.9	-1.5
Body weight	6.4	27.8	35.2	-5.9	-5.9	5.9	5.3	5.4	5.1	-5.2	-5.1	-4.9	4.7	-4.3
Weight adjusted by age	0.1	0.3	1.1	-0.6	-0.6	0.5	0.6	0.6	1.1	-0.3	-0.0	-0.1	-0.2	0.4
Bone surface	0.0	0.1	0.2	-0.1	-0.1	0.1	-0.4	-0.3	-0.4	0.3	0.3	0.2	-0.1	0.5
Bone volume	0.2	0.3	0.6	0.1	0.1	-0.1	-0.6	-0.6	-0.6	0.7	0.7	0.6	-0.4	0.8
Breakpoint value in progressive ratio session	0.0	0.1	0.5	-0.1	-0.1	0.0	0.7	0.1	0.6	0.1	0.1	0.1	-0.2	0.2
Number of licking bursts	0.1	0.2	0.5	0.2	0.2	-0.1	-0.5	-0.7	-0.3	0.4	0.4	0.6	-0.1	0.5
Context. condit. distance diff. score	1.4	1.7	3.1	-1.1	-1.1	1.0	1.1	1.6	1.3	-1.5	-1.4	-1.8	0.9	-1.4
Locomotion velocity, session 1	0.5	0.6	0.9	-1.0	-1.0	0.9	0.7	0.8	0.8	-0.6	-0.6	-0.7	0.6	-0.5
Locomotion distance, session 1	2.2	2.8	4.0	-2.0	-2.0	2.0	1.5	1.7	1.7	-1.5	-1.4	-1.7	1.5	-1.2
Locomotion velocity, session 2	0.1	0.2	0.3	-0.4	-0.4	0.4	0.6	0.5	0.3	-0.4	-0.4	-0.3	0.2	-0.3
Locomotion distance, session 2	0.1	0.1	0.4	-0.6	-0.6	0.6	0.2	0.2	0.3	-0.0	-0.1	-0.1	0.2	0.1
Locomotion velocity, session 3	0.0	0.0	0.1	0.3	0.3	-0.3	0.1	-0.1	-0.1	-0.1	-0.1	0.1	-0.3	0.2
Locomotion distance, session 3	0.2	0.2	0.5	-0.5	-0.5	0.5	0.6	0.4	0.7	-0.5	-0.5	-0.4	0.4	-0.4
Stereotopy head waving bouts, day 3	2.4	2.9	3.5	1.8	1.8	-1.8	-1.9	-1.4	-1.8	1.5	1.4	1.6	-1.8	1.7
Stereotopy head waving duration, day 3	0.2	0.2	0.6	0.3	0.3	-0.4	-0.7	-0.1	-0.7	0.4	0.2	0.3	-0.6	0.5
Locomotion velocity, session 7	1.1	1.2	1.6	-1.2	-1.2	1.3	1.0	0.8	1.2	-1.2	-1.1	-0.9	1.2	-0.9
Locomotion distance, session 7	0.5	0.6	1.3	-0.7	-0.7	0.8	0.5	0.3	0.9	-0.7	-0.6	-0.8	1.1	-1.0
Stereotopy head waving bouts, day 7	0.6	0.7	1.4	0.7	0.7	-0.8	-1.0	-0.6	-0.8	0.7	0.8	0.8	-1.2	1.2
Stereotopy head waving duration, day 7	0.3	0.4	1.3	0.4	0.4	-0.5	-0.4	-0.1	-0.5	0.4	0.5	0.6	-1.1	1.0
Locomotion velocity, session 8	7.9	9.5	11.2	-3.2	-3.1	3.1	3.0	3.3	3.1	-3.0	-3.1	-3.3	2.8	-3.0
Locomotion distance, session 8	1.4	2.0	2.7	-1.6	-1.6	1.5	1.3	1.6	1.4	-1.3	-1.3	-1.7	1.1	-1.1
Degree of sensitization distance	1.0	1.1	2.0	-1.0	-1.0	1.0	0.9	0.8	0.8	-1.0	-1.0	-1.2	1.4	-1.4
Degree of sensitization stereotypy	0.6	0.7	1.4	0.6	0.7	-0.7	-1.0	-0.6	-0.8	0.7	0.8	0.8	-1.1	1.2
Conditioned locomotion	0.2	0.3	0.6	0.6	0.6	-0.6	-0.3	-0.3	-0.4	0.5	0.4	0.5	-0.8	0.6
Cocaine response after cond. corrected	0.5	0.7	2.1	0.3	0.4	-0.5	-1.4	-0.5	-0.7	0.9	0.8	0.9	-1.0	1.3
Cocaine response after cond. not corrected	0.6	0.9	2.8	0.4	0.4	-0.5	-1.7	-0.6	-0.6	1.0	0.9	0.9	-1.0	1.4
Cocaine response before conditioning	0.0	0.0	0.2	0.2	0.2	-0.2	-0.5	-0.2	0.1	0.2	0.2	-0.0	-0.1	0.0
Saline control response	0.6	0.8	1.3	-1.1	-1.1	1.0	0.3	1.0	0.8	-0.9	-0.9	-0.9	0.7	-0.5
Bone: connectivity density	3.4	5.4	6.4	2.2	2.2	-2.2	-2.2	-2.3	-2.3	2.5	2.5	2.3	-2.3	2.4
Bone: cortical apparent density	4.6	7.3	9.9	3.1	3.1	-3.1	-2.7	-2.8	-2.4	2.6	2.7	2.4	-2.4	2.0
Bone: cortical area	0.1	0.1	0.3	0.3	0.3	-0.3	-0.5	-0.4	-0.3	0.3	0.3	0.3	-0.4	0.4
Bone: cortical porosity	0.4	0.4	1.0	0.2	0.3	-0.4	-1.0	-0.4	-0.7	0.7	0.7	0.6	-0.8	1.0
Bone: cortical porosity	0.1	0.2	0.6	-0.2	-0.2	0.1	-0.8	0.0	-0.3	0.3	0.3	0.2	-0.5	0.7
Bone: cortical thickness	1.0	1.6	2.3	1.4	1.4	-1.5	-1.3	-1.1	-0.9	1.2	1.2	1.1	-1.5	1.3
Bone: cortical thickness	4.8	5.9	8.7	2.4	2.5	-2.6	-2.1	-2.0	-2.2	2.4	2.4	2.3	-3.0	2.7
Bone: cortical tissue density	4.6	7.3	9.9	3.2	3.1	-3.1	-2.7	-2.8	-2.4	2.7	2.7	2.5	-2.4	2.0
Condit. Reinf. active minus inactive responses	1.2	1.4	1.9	1.3	1.4	-1.4	-0.9	-1.1	-0.9	1.1	1.1	1.2	-1.2	1.0
Condit. Reinf. active-inactive response ratio	1.5	1.6	2.5	1.5	1.6	-1.6	-1.0	-1.2	-0.8	1.2	1.1	1.4	-1.3	1.0
Condit. Reinf. active responses	1.0	1.3	1.8	1.3	1.3	-1.4	-0.9	-1.1	-0.9	1.1	1.1	1.2	-1.1	1.0
Condit. Reinf. inactive responses	0.0	0.1	0.1	0.2	0.2	-0.2	-0.2	-0.2	-0.3	0.3	0.3	0.3	-0.2	0.3
Incentive salience index mean	2.1	2.7	3.3	1.8	1.8	-1.8	-1.5	-1.8	-1.6	1.6	1.5	1.7	-1.5	1.4
Condit. Reinf. lever presses	1.3	1.9	2.9	1.4	1.4	-1.4	-1.4	-1.7	-1.5	1.3	1.3	1.3	-1.0	1.2
Condit. Reinf. active minus inactive responses	0.9	1.4	2.1	1.2	1.2	-1.1	-0.8	-1.4	-1.0	1.3	1.3	1.3	-1.0	1.1
Condit. Reinf. active-inactive response ratio	0.8	1.2	1.7	1.1	1.0	-0.9	-0.9	-1.3	-1.1	1.3	1.2	1.2	-0.8	1.1
Condit. Reinf. active responses	1.6	2.3	3.1	1.5	1.5	-1.4	-1.2	-1.8	-1.4	1.6	1.6	1.7	-1.3	1.6
Condit. Reinf. inactive responses	1.3	1.9	2.3	1.3	1.3	-1.3	-1.5	-1.5	-1.3	1.4	1.4	1.5	-1.3	1.5
Condit. Reinf. lever presses	0.1	0.2	0.3	0.4	0.5	-0.4	-0.4	-0.4	-0.2	0.3	0.3	0.5	-0.5	0.5
Condit. Reinf. lever reinforcers received	1.8	2.6	3.3	1.6	1.6	-1.6	-1.3	-1.8	-1.4	1.7	1.6	1.8	-1.5	1.6
Conditioned reinforcement - actives	0.0	0.1	0.5	0.4	0.4	-0.3	-0.7	-0.5	0.2	0.2	0.1	0.4	0.1	-0.1
Conditioned reinforcement - inactives	0.1	0.3	0.5	0.6	0.6	-0.5	-0.4	-0.6	-0.5	0.7	0.6	0.5	0.0	-0.1
Conditioned locomotion	0.5	0.7	1.6	1.0	0.9	-0.8	-0.9	-1.3	-0.4	0.7	0.7	1.0	-0.4	0.6
Patch foraging indifference point 0 sec	1.1	3.1	4.5	2.1	2.0	-1.9	-2.1	-2.1	-1.6	1.6	1.6	1.6	-1.2	1.1
Patch foraging indifference point AUC	0.0	0.0	0.1	-0.3	-0.3	0.2	-0.3	0.3	0.0	-0.1	-0.1	-0.2	-0.1	0.1
Delay disc. indifference point, 0s delay	1.8	2.0	2.2	1.5	1.4	-1.4	-1.5	-1.4	-1.4	1.4	1.3	1.3	-1.4	1.4
Delay disc. indifference point, 16s delay	0.2	0.3	1.1	0.4	0.5	-0.7	-0.6	0.2	-0.4	0.5	0.3	0.2	-1.1	0.6
Delay disc. indifference point, 2s delay	1.0	1.2	2.6	1.0	0.9	-0.9	-1.6	-1.2	-0.7	1.1	1.1	1.0	-0.9	1.2
Delay disc. indifference point, 24s delay	0.1	0.1	0.2	-0.2	-0.2	0.2	-0.1	0.4	0.1	-0.4	-0.4	-0.3	0.3	-0.5
Delay disc. indifference point, 4s delay	1.2	1.2	2.4	0.9	1.0	-1.1	-0.9	-0.7	-0.8	1.1	1.0	1.2	-1.5	1.5
Delay disc. indifference point, 8s delay	0.1	0.2	0.4	0.4	0.3	-0.3	-0.6	-0.4	-0.6	0.4	0.2	0.4	-0.3	0.3
Indifference point function ln k	0.0	0.0	0.1	0.1	0.1	-0.2	-0.1	0.2	0.2	-0.4	-0.3	-0.1	-0.1	-0.2
Indifference point function log k	0.0	0.0	0.1	0.1	0.1	-0.2	-0.1	0.2	0.2	-0.4	-0.3	-0.1	-0.1	-0.2
Patch foraging total patch changes 0 sec	0.7	2.0	3.4	1.7	1.6	-1.5	-1.8	-1.8	-1.3	1.3	1.2	1.2	-0.8	0.8
Patch foraging total patch changes 12 sec	4.7	6.3	8.1	2.6	2.5	-2.4	-2.6	-2.8	-2.4	2.6	2.7	2.4	-2.2	2.4
Patch foraging total patch changes 18 sec	0.2	0.5	1.0	0.8	0.7	-0.6	-0.9	-1.0	-0.6	0.6	0.6	0.6	-0.3	0.4
Patch foraging total patch changes 24 sec	0.4	1.3	1.6	1.1	1.1	-1.1	-1.3	-1.1	-0.6	1.3	1.1	1.1	-1.3	1.2
Patch foraging total patch changes 6 sec	1.5	2.5	3.4	1.7	1.7	-1.6	-1.8	-1.8	-1.7	1.5	1.5	1.4	-1.2	1.2
Patch foraging time to switch 0 sec	0.0	0.1	0.2	0.3	0.3	-0.3	-0.1	-0.3	-0.2	0.4	0.5	0.4	-0.3	0.4
Patch foraging water rate 0 sec	0.0	0.2	0.3	0.5	0.5	-0.5	-0.3	-0.5	-0.5	0.3	0.3	0.4	-0.3	0.2
Patch foraging water rate 12 sec	0.0	0.1	0.4	-0.1	-0.0	0.0	0.7	0.2	0.6	-0.3	-0.1	0.1	-0.1	-0.0
Patch foraging water rate 18 sec	0.4	0.8	1.6	0.7	0.7	-0.7	-0.8	-0.8	-0.7	0.8	1.0	1.0	-1.2	1.3
Patch foraging water rate 24 sec	0.5	0.8	1.6	0.9	0.9	-0.9	-0.7	-1.0	-1.3	0.7	0.8	0.8	-0.7	0.7
Patch foraging water rate 6 sec	1.8	2.7	3.2	1.7	1.7	-1.7	-1.3	-1.6	-1.6	1.4	1.6	1.7	-1.8	1.8
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.3	0.3	0.4	-0.4	0.4	0.1	0.6	0.0	-0.1	-0.1	-0.1	-0.3
Distance traveled before self-admin	0.1	0.1	0.4	0.1	0.1	-0.2	0.1	-0.1	-0.3	0.3	0.3	0.4	-0.5	0.6
Distance traveled after self-admin	0.3	0.5	0.9	-0.8	-0.8	0.8	1.0	0.9	0.3	-0.7	-0.8	-0.6	0.5	-0.5
Extensor digitorum longus weight	9.7	38.7	41.2	-6.2	-6.1	6.2	6.2	6.0	6.4	-6.4	-6.4	-6.1	6.2	-6.3
Bone: elastic displacement	0.1	0.1	0.3	0.1	0.0	0.1	-0.2	-0.2	0.2	-0.1	-0.1	-0.2	0.5	-0.5
Bone: elastic work	0.1	0.1	0.3	0.1	0.1	-0.2	-0.4	-0.2	-0.2	0.3	0.3	0.2	-0.4	0.5
Bone: endosteal estimation	1.9	4.6	6.7	-2.5	-2.6	2.6	1.7	1.9	1.7	-2.1	-2.1	-2.0	2.3	-1.8
Bone: endosteal perimeter	1.1	2.7	3.9	-1.7	-1.8	1.9	1.6	1.3	1.2	-1.7	-1.6	-1.6	2.0	-1.7
Epididymis fat weight	0.1	0.4	0.8	-0.9	-0.9	0.8	0.6	0.7	0.7	-0.5	-0.5	-0.6	0.4	-0.2
Delta time in closed arm before/after self-admin	4.9	4.6	5.9	-2.3	-2.3	2.2	2.4	2.4	2.1	-2.0	-1.9	-2.2	1.8	-1.8
Delta time in open arm before/after self-admin	0.0	0.0	0.1	-0.1	-0.1	-0.0	0.0	0.3	-0.0	0.1	-0.1	-0.0	-0.1	-0.0
Diff in mean of infusions in LGA sessions	0.0	0.1	0.3	0.1	0.1	-0.1	0.6	-0.1	0.2	0.3	0.3	0.2	-0.4	0.4
Delay discount exponential model param	0.2	0.2	0.6	-0.4	-0.4	0.5	0.7	0.1	0.4	-0.4	-0.3	-0.4	0.8	-0.6
Extinction: sum of active levers before priming	1.1	1.7	2.4	-1.5	-1.5	1.5	0.9	1.4	1.3	-1.3	-1.2	-1.3	1.2	-1.1
Active lever presses in extinction session 6	0.6	0.6	2.8	0.0	0.0	-0.2	-1.0	-0.2	-0.7	0.5	0.6	0.7	-1.3	1.7
Bone: final force	0.5	0.8	1.8	0.5	0.4	-0.5	-1.3	-0.8	-0.9	0.8	0.8	0.9	-0.9	1.3
Bone: final moment	0.3	0.5	1.4	0.3	0.2	-0.3	-1.2	-0.6	-0.8	0.6	0.7	0.7	-0.7	1.1
Food consumed during 24 hour testing period	0.5	1.0	1.2	-1.0	-1.0	1.1	1.0	0.9	0.8	-1.1	-1.0	-1.0	1.0	-0.9
Glucose	0.1	0.2	1.0	-0.4	-0.4	0.4	-1.0	0.1	0.1	-0.3	-0.3	-0.3	0.0	0.3
Heart weight	3.4	5.5	6.2	-2.4	-2.4	2.4	2.1	2.2	2.5	-2.4	-2.4	-2.5	2.4	-2.3
Delay discount hyperbolic model param	0.2	0.2	0.5	-0.4	-0.4	0.5	0.7	0.1	0.3	-0.4	-0.3	-0.4	0.7	-0.6
Intermittent access intake day 1-15 change	0.0	0.2	0.5	0.3	0.3	-0.4	0.5	-0.0	-0.5	0.5	0.4	0.4	-0.7	0.6
Intermittent access intake escalation	0.0	0.2	0.4	0.2	0.3	-0.3	0.5	0.1	-0.4	0.5	0.3	0.3	-0.7	0.5
Intermittent access intake escalation 2	0.1	0.2	0.9	-0.4	-0.4	0.4	0.9	0.5	-0.1	-0.1	-0.3	-0.4	0.3	-0.3
Intermitt. access day 1 inactive lever presses	0.2	2.6	4.5	1.4	1.5	-1.6	-0.9	-1.1	-1.7	1.7	1.8	1.6	-2.1	1.9
Intermitt. access day 15 inactive lever presses	0.5	2.6	3.5	1.8	1.8	-1.8	-1.1	-1.6	-1.9	1.6	1.5	1.7	-1.4	1.2
Intermitt. access escalation Index	0.8	2.4	3.9	-1.8	-1.7	1.6	2.0	2.0	1.4	-1.6	-1.4	-1.5	0.7	-0.7
Intermittent access day 1 total infusions	0.0	0.0	0.1	0.1	0.1	-0.1	-0.3	-0.0	0.1	0.2	0.1	0.0	-0.0	-0.1
Intermittent access day 15 total infusions	0.0	0.1	0.3	0.0	0.1	-0.2	0.2	0.4	-0.1	0.3	0.1	0.1	-0.5	0.3
Intermittent access terminal intake (last 3 days)	0.1	0.2	0.5	0.4	0.4	-0.5	-0.3	-0.0	-0.7	0.6	0.5	0.4	-0.6	0.4
Intermittent access total infusions	0.0	0.0	0.1	0.1	0.1	-0.2	-0.1	0.3	-0.1	0.3	0.2	0.1	-0.3	0.1
Intermittent access day 1 locomotion	0.0	0.1	0.3	0.2	0.2	-0.2	-0.5	-0.3	0.2	0.1	0.0	0.1	0.2	-0.2
Intermittent access day 15 total locomotion	0.1	0.3	0.8	0.6	0.5	-0.5	-0.9	-0.8	-0.2	0.6	0.5	0.5	-0.1	0.3
Intermittent access total locomotion	0.7	0.9	1.7	1.0	1.0	-1.0	-1.3	-1.0	-0.7	1.0	0.9	0.9	-0.7	0.6
Intermittent access standard deviation	0.5	2.4	3.3	1.6	1.6	-1.6	-0.8	-1.3	-1.8	1.8	1.8	1.5	-1.5	1.3
Left kidney weight	0.2	1.8	4.5	-1.5	-1.4	1.3	2.1	1.7	0.8	-1.4	-1.2	-1.1	0.5	-0.6
Right kidney weight	0.0	0.2	0.6	-0.5	-0.4	0.3	0.8	0.4	-0.5	0.1	0.3	0.1	-0.5	0.6
Cocaine induced anxiety	1.3	3.5	5.1	-2.1	-2.1	2.0	2.1	2.3	1.6	-1.9	-1.8	-1.8	1.3	-1.3
Post-drug Anxiety	0.6	0.7	1.4	-1.0	-0.9	0.9	0.9	1.2	0.6	-0.9	-0.8	-0.8	0.6	-0.7
Baseline Anxiety	1.2	2.1	4.5	1.6	1.5	-1.5	-2.1	-1.7	-1.1	1.4	1.3	1.4	-0.8	0.9
Tail length	0.3	1.6	2.2	-1.3	-1.3	1.2	1.5	1.5	1.3	-1.4	-1.3	-1.2	0.9	-1.0
Length with tail	2.1	9.4	14.0	-3.3	-3.3	3.2	3.7	3.3	3.2	-3.0	-2.9	-2.8	2.4	-2.4
Length without tail	1.7	9.1	10.9	-3.2	-3.2	3.3	3.3	2.8	3.2	-3.0	-2.9	-2.8	2.8	-2.6
Times rat made contact with spout	0.7	0.8	1.4	0.9	0.8	-0.8	-1.0	-1.2	-1.2	0.9	1.0	0.9	-0.4	0.6
Lifetime Intake	0.1	0.2	0.4	0.3	0.4	-0.5	-0.2	0.0	-0.3	0.6	0.4	0.4	-0.6	0.4
Liver weight, left	0.2	0.4	0.7	-0.8	-0.8	0.8	0.4	0.5	0.6	-0.5	-0.5	-0.5	0.7	-0.5
Liver weight, right	0.4	0.7	1.8	0.4	0.4	-0.6	-1.2	0.0	-1.0	0.6	0.6	0.4	-1.4	1.2
Locomotor activity	0.5	0.8	1.5	0.6	0.6	-0.6	-1.1	-0.9	-0.8	1.0	1.1	1.0	-0.9	1.2
Locomotor testing distance	1.5	3.6	4.0	1.8	1.8	-1.8	-2.0	-1.9	-2.0	1.9	2.0	1.9	-1.9	2.0
Locomotor testing rearing	2.7	9.8	11.9	3.3	3.3	-3.3	-3.2	-3.0	-3.4	2.9	2.9	3.0	-3.1	2.9
Locomotion in novel chamber	4.1	5.5	7.8	2.4	2.4	-2.5	-2.8	-2.3	-1.9	2.2	2.2	2.3	-2.4	2.4
Locomotion in novel chamber post-restriction	0.2	0.5	0.9	0.6	0.6	-0.5	-0.6	-0.9	-0.8	0.7	0.6	0.9	-0.4	0.8
Fecal boli incidents, locomotor time 1	0.2	0.4	1.1	-0.5	-0.5	0.6	0.1	0.3	0.9	-0.6	-0.6	-0.5	1.0	-0.9
Change in fecal boli incidents, locomotor task	0.1	0.1	0.2	0.1	0.1	-0.2	-0.3	-0.1	0.0	0.2	0.3	0.0	-0.5	0.4
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.6	0.6	0.6	-0.6	-0.7	-0.4	0.4	0.1	0.2	0.3	-0.3	0.1
Bouts of movement, locomotor time 1	0.3	0.3	0.9	-0.7	-0.7	0.7	1.0	0.7	0.4	-0.4	-0.4	-0.3	0.4	-0.3
Total resting periods, locomotor time 1	0.7	0.9	1.3	-1.1	-1.1	1.1	1.1	1.0	0.8	-0.6	-0.6	-0.7	0.9	-0.7
Rest time, locomotor task time 1	0.0	0.0	0.1	0.0	-0.0	0.1	0.2	-0.4	-0.2	0.2	0.0	0.1	0.3	-0.1
Distance moved, locomotor task time 1	0.0	0.1	0.3	-0.2	-0.1	-0.1	-0.5	0.5	0.6	-0.2	-0.2	-0.2	-0.4	0.3
Vertical activity count, locomotor time 1	0.1	0.4	2.5	-0.6	-0.6	0.5	0.1	0.6	1.6	-0.5	-0.5	-0.5	0.3	-0.4
Time >=10cm from walls, locomotor time 2	0.4	1.1	2.4	1.0	1.0	-1.0	-1.6	-1.2	-0.0	0.8	1.1	1.2	-1.0	1.1
Bouts of movement, locomotor time 2	0.2	0.6	1.1	0.8	0.8	-0.8	-0.2	-0.7	-1.0	0.6	0.7	0.9	-0.9	0.8
Total resting periods, locomotor time 2	0.1	0.4	0.6	0.6	0.7	-0.7	0.1	-0.5	-0.8	0.4	0.5	0.7	-0.8	0.6
Rest time, locomotor task time 2	0.5	0.8	1.6	-0.9	-0.9	0.9	1.0	0.8	1.2	-0.8	-0.8	-0.7	0.9	-0.8
Distance moved, locomotor task time 2	0.2	0.3	0.6	-0.7	-0.7	0.5	-0.5	0.7	0.7	-0.6	-0.7	-0.6	0.2	-0.1
Vertical activity count, locomotor time 2	0.3	0.6	2.1	-0.8	-0.8	0.7	0.2	0.8	1.5	-0.7	-0.8	-0.8	0.6	-0.7
Light reinforcement 1	1.1	5.1	5.9	2.3	2.3	-2.2	-1.8	-2.3	-2.3	2.4	2.4	2.2	-2.2	2.3
Light reinforcement 2	0.3	0.6	1.2	0.4	0.4	-0.5	-0.9	-0.6	-1.1	0.9	1.0	0.5	-0.9	1.1
Bone: marrow area	1.8	4.3	6.3	-2.4	-2.5	2.5	1.7	1.9	1.6	-2.1	-2.0	-2.0	2.2	-1.8
Bone: maximum diameter	0.0	0.0	0.1	0.1	0.1	-0.1	-0.1	-0.3	-0.3	0.2	0.2	0.3	-0.2	0.3
Bone: maximum force	0.1	0.1	0.3	-0.5	-0.6	0.5	-0.1	0.3	0.1	-0.3	-0.3	-0.2	0.1	0.2
Bone: maximum moment	0.1	0.2	0.5	-0.7	-0.7	0.7	0.0	0.5	0.2	-0.5	-0.5	-0.5	0.3	-0.0
Mean time between licks in bursts	0.4	2.3	4.1	-1.4	-1.5	1.6	1.4	0.9	1.2	-1.5	-1.6	-1.4	2.0	-1.8
Mean num. licks in bursts	0.0	0.1	0.3	0.4	0.4	-0.5	-0.3	-0.1	-0.5	0.2	0.3	0.1	-0.3	0.1
Cd content in liver	1.6	1.8	2.4	-1.2	-1.3	1.3	1.4	1.2	1.2	-1.3	-1.4	-1.3	1.5	-1.5
Co content in liver	1.9	2.2	3.4	-1.3	-1.3	1.3	1.7	1.5	1.4	-1.4	-1.4	-1.6	1.6	-1.9
Cu content in liver	0.1	0.1	0.2	0.4	0.4	-0.5	0.1	-0.0	0.1	0.2	0.2	0.2	-0.4	0.2
Fe content in liver	1.7	2.1	3.0	-1.7	-1.7	1.7	1.1	1.6	1.3	-1.4	-1.4	-1.5	1.3	-1.1
K content in liver	1.4	1.3	3.4	1.0	1.1	-1.2	-0.9	-0.5	-0.9	1.1	1.0	1.1	-1.8	1.6
Mg content in liver	0.9	1.0	2.5	1.1	1.1	-1.3	-0.8	-0.4	-0.8	0.8	0.8	0.8	-1.6	1.1
Mn content in liver	1.5	1.7	2.4	1.5	1.5	-1.6	-1.1	-1.2	-1.0	1.2	1.2	1.2	-1.4	1.1
Na content in liver	0.4	0.4	1.6	0.0	0.1	-0.2	-0.6	-0.2	-0.5	0.7	0.8	0.7	-1.0	1.3
Rb content in liver	1.6	1.8	3.7	1.5	1.4	-1.4	-1.9	-1.4	-1.5	1.3	1.2	1.1	-1.0	0.9
Se content in liver	8.1	9.6	11.7	3.2	3.2	-3.3	-2.8	-2.7	-3.0	3.0	3.1	3.1	-3.4	3.2
Sr content in liver	0.1	0.1	0.6	0.2	0.2	-0.2	0.8	0.1	0.5	-0.2	-0.2	-0.2	0.1	-0.4
Zn content in liver	3.5	4.1	5.2	2.1	2.1	-2.2	-1.7	-1.7	-2.1	1.9	1.9	2.0	-2.3	2.1
Bone: minimum diameter	0.5	0.9	1.4	-1.2	-1.2	1.1	0.4	1.0	0.8	-1.1	-1.1	-1.0	0.9	-0.7
Time in familiar zone, hab. session 1	0.1	0.1	0.6	-0.2	-0.2	0.1	-0.4	-0.1	-0.5	0.1	0.1	0.3	-0.4	0.8
Time in novel zone, hab. session 1	0.6	0.6	1.4	1.2	1.2	-1.1	-0.9	-0.8	-0.3	0.6	0.6	0.6	-0.4	0.1
Total zone transitions, hab. session 1	1.9	2.7	3.1	-1.6	-1.6	1.6	1.6	1.7	1.7	-1.7	-1.7	-1.8	1.4	-1.5
Total locomotion distance, hab. session 1	0.0	0.0	0.1	-0.0	0.0	-0.1	0.2	0.3	0.3	-0.1	-0.1	-0.2	-0.1	-0.0
Locomotion velocity, hab. session 1	0.2	0.3	1.0	-0.5	-0.5	0.4	1.0	0.8	0.8	-0.3	-0.4	-0.6	0.1	-0.3
Time in familiar zone, hab. session 2	0.5	0.6	1.3	0.4	0.4	-0.6	-0.9	-0.3	-0.7	0.8	1.0	0.7	-1.1	1.1
Time in novel zone, hab. session 2	0.2	0.2	0.5	0.7	0.7	-0.6	-0.1	-0.7	-0.2	0.3	0.2	0.5	-0.1	0.0
Total zone transitions, hab. session 2	1.2	1.5	2.0	-1.3	-1.3	1.3	0.7	1.1	1.4	-1.2	-1.1	-1.3	1.4	-1.3
Total locomotion distance, hab. session 2	0.3	0.4	0.6	-0.7	-0.7	0.7	0.4	0.5	0.8	-0.3	-0.3	-0.6	0.8	-0.6
Locomotion velocity, hab. session 2	0.5	0.7	1.0	-0.9	-0.9	0.9	0.7	0.7	1.0	-0.5	-0.6	-0.8	0.9	-0.8
Novel to familiar place preference ratio	0.8	1.0	2.8	-0.9	-0.8	0.8	1.7	1.3	1.0	-1.2	-1.0	-0.8	0.4	-0.7
Novelty place preference	0.7	0.9	2.6	-0.8	-0.7	0.6	1.6	1.2	0.9	-1.1	-1.0	-0.8	0.3	-0.7
Time in novel zone, NPP test	0.3	0.4	1.4	-0.4	-0.3	0.3	1.2	0.8	0.7	-0.7	-0.6	-0.4	-0.0	-0.3
Total zone transitions, NPP test	0.6	0.9	1.7	-1.1	-1.2	1.2	0.2	0.6	1.0	-0.7	-0.6	-1.1	1.3	-0.9
Total locomotion distance, NPP test	0.1	0.1	0.3	-0.4	-0.4	0.5	-0.4	-0.0	0.2	0.0	0.0	-0.4	0.6	-0.2
Locomotion velocity, NPP test	0.4	0.6	1.2	-0.8	-0.9	0.9	0.3	0.5	0.4	-0.5	-0.5	-0.9	1.1	-0.8
Intraocular pressure	3.0	4.9	7.6	-2.1	-2.2	2.2	1.7	2.0	1.8	-2.3	-2.2	-2.2	2.8	-2.7
Delta distance traveled before/after self-admin	1.4	1.5	1.9	-1.2	-1.2	1.2	1.2	1.4	1.2	-1.2	-1.3	-1.2	1.1	-1.2
Delta ambulatory time before/after self-admin	1.1	1.8	2.3	-1.5	-1.5	1.5	1.0	1.5	1.1	-1.5	-1.4	-1.3	1.2	-1.2
Parametrial fat weight	0.5	1.1	1.9	0.8	0.8	-0.8	-0.7	-1.1	-1.2	1.1	1.1	1.2	-1.1	1.4
Pavlov. Cond. lever latency	2.1	2.6	3.7	-1.4	-1.3	1.3	1.8	1.8	1.9	-1.6	-1.6	-1.7	1.3	-1.7
Pavlov. Cond. magazine entry latency	9.7	12.4	13.8	3.4	3.4	-3.4	-3.4	-3.5	-3.7	3.6	3.6	3.6	-3.4	3.7
Pavlov. Cond. change in total contacts	9.3	10.0	11.6	3.4	3.4	-3.4	-3.1	-3.1	-3.4	2.9	2.9	3.1	-3.1	3.0
Pavlov. Cond. index score	8.0	10.2	11.9	3.1	3.0	-3.0	-3.4	-3.4	-3.4	3.2	3.2	3.3	-2.8	3.2
Pavlov. Cond. latency score	6.0	7.6	9.3	2.6	2.5	-2.5	-2.9	-2.9	-3.0	2.8	2.8	2.9	-2.5	2.8
Pavlov. Cond. lever contacts	2.8	3.4	4.7	1.7	1.6	-1.6	-1.9	-2.1	-2.2	1.8	1.8	2.0	-1.5	1.9
Pavlov. Cond. magazine entry number	12.2	15.5	17.8	-3.9	-3.9	3.9	4.1	4.0	4.2	-3.9	-3.9	-3.9	3.7	-3.8
Pavlov. Cond. intertrial magazine entries	1.2	1.5	2.5	-1.1	-1.1	1.1	1.0	1.2	1.6	-1.2	-1.3	-1.2	1.2	-1.4
Pavlov. Cond. lever-magazine prob. diff.	9.7	12.0	13.9	3.4	3.3	-3.3	-3.6	-3.7	-3.7	3.5	3.5	3.5	-3.1	3.4
Pavlov. Cond. response bias	10.1	12.6	14.3	3.5	3.5	-3.5	-3.6	-3.6	-3.8	3.5	3.5	3.5	-3.4	3.5
Pavlov. Cond. lever latency	0.5	0.7	0.9	-0.8	-0.8	0.7	0.7	1.0	0.9	-0.9	-0.8	-0.9	0.8	-0.9
Pavlov. Cond. magazine entry latency	0.0	0.1	0.2	-0.3	-0.3	0.3	0.2	0.2	0.4	-0.1	-0.1	-0.2	0.2	-0.2
Pavlov. Cond. change in total contacts	0.4	0.9	1.6	1.2	1.1	-1.1	-1.0	-1.3	-1.0	0.7	0.7	1.0	-0.6	0.6
Pavlov. Cond. index score	0.1	0.2	0.4	0.4	0.4	-0.3	-0.5	-0.6	-0.4	0.4	0.4	0.5	-0.2	0.3
Pavlov. Cond. latency score	0.1	0.1	0.2	0.3	0.2	-0.2	-0.4	-0.5	-0.3	0.3	0.3	0.3	-0.1	0.2
Pavlov. Cond. lever contacts	0.5	0.7	1.0	0.7	0.7	-0.7	-0.9	-1.0	-0.9	0.8	0.8	0.9	-0.7	0.9
Pavlov. Cond. magazine entry number	0.1	0.1	0.2	-0.2	-0.2	0.2	0.4	0.3	0.1	-0.2	-0.2	-0.3	0.3	-0.3
Pavlov. Cond. intertrial magazine entries	0.9	1.9	3.9	-1.0	-1.0	1.0	2.0	1.3	1.5	-1.4	-1.4	-1.4	1.1	-1.5
Pavlov. Cond. lever-magazine prob. diff.	0.0	0.1	0.2	0.2	0.2	-0.2	-0.4	-0.4	-0.3	0.2	0.2	0.3	-0.1	0.2
Pavlov. Cond. response bias	1.0	1.4	1.6	1.1	1.1	-1.0	-1.2	-1.3	-1.2	1.2	1.2	1.3	-1.1	1.2
Time in closed arm before self-admin	1.4	2.4	4.5	1.7	1.7	-1.7	-1.9	-1.5	-2.1	1.3	1.1	1.3	-1.4	1.1
Time in closed arm after self-admin	0.1	0.1	0.3	-0.1	-0.1	0.1	0.4	0.5	0.0	-0.5	-0.5	-0.5	-0.0	-0.4
Time in open arm before self-admin	1.3	1.6	4.1	-1.4	-1.3	1.3	1.4	1.2	2.0	-1.1	-1.0	-1.1	0.8	-0.7
Time in open arm after self-admin	0.2	0.2	0.5	-0.5	-0.5	0.5	0.6	0.5	0.7	-0.2	-0.4	-0.5	0.4	-0.4
Bone: periosteal estimation	0.2	0.6	1.1	-1.0	-1.0	1.0	0.4	0.6	0.5	-0.7	-0.7	-0.7	0.7	-0.4
Bone: periosteal perimeter	0.6	1.2	1.9	-1.3	-1.3	1.4	1.0	0.8	0.7	-1.0	-1.0	-1.0	1.3	-0.9
Bone: post-yield work	1.1	1.8	2.4	-1.4	-1.4	1.4	1.4	1.2	1.0	-1.5	-1.5	-1.4	1.3	-1.3
Progressive ratio test 1 active lever presses	0.1	0.1	0.7	0.1	0.1	-0.2	-0.8	0.0	-0.3	0.1	0.1	0.2	-0.4	0.3
Progressive ratio test 1 breakpoint	0.0	0.1	0.5	0.0	0.0	-0.1	-0.7	0.1	-0.2	-0.0	0.0	0.1	-0.2	0.2
Progressive ratio test 1 inactive lever presses	0.1	0.3	0.7	0.5	0.5	-0.6	-0.4	-0.2	-0.6	0.6	0.6	0.6	-0.8	0.6
Progressive ratio test 2 active lever presses	0.8	1.1	1.3	1.1	1.1	-1.1	-1.1	-1.1	-1.0	1.1	1.1	1.1	-0.9	0.8
Progressive ratio test 2 breakpoint	0.9	1.2	1.4	1.1	1.1	-1.1	-1.1	-1.1	-1.0	1.2	1.1	1.1	-0.9	0.9
Progressive ratio test 2 inactive lever presses	0.1	0.2	0.5	0.5	0.5	-0.5	-0.5	-0.5	-0.5	0.7	0.6	0.5	-0.3	0.2
Incentive Sensitization - Responses	0.7	2.0	3.5	1.6	1.5	-1.4	-1.2	-1.9	-1.4	1.7	1.6	1.4	-0.7	0.9
Incentive Sensitization - Breakpoint	0.8	1.8	3.1	1.5	1.4	-1.3	-1.1	-1.8	-1.4	1.6	1.5	1.3	-0.7	0.9
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.7	-0.1	-0.1	-0.0	-0.8	0.2	-0.1	0.1	0.2	0.0	-0.6	0.7
Progressive ratio	0.0	0.1	0.4	0.2	0.2	-0.3	-0.0	-0.3	0.2	0.2	0.4	0.4	-0.6	0.7
Food seeking constrained by brief footshock	0.5	0.6	1.3	0.6	0.5	-0.6	-0.8	-0.6	-1.2	0.7	0.7	0.7	-0.9	1.0
Seeking ratio, punishment vs. effort	0.0	0.1	0.3	-0.1	-0.1	0.1	-0.2	0.2	-0.5	-0.1	-0.2	-0.2	0.2	-0.3
Retroperitoneal fat weight	0.0	0.2	0.6	0.4	0.4	-0.4	-0.6	-0.4	-0.8	0.4	0.4	0.3	-0.4	0.5
Reaction time number correct	0.3	1.1	1.4	-1.1	-1.1	1.1	1.2	0.8	1.2	-1.0	-1.1	-1.1	1.1	-0.9
Reaction time mean minus median	0.1	0.6	1.2	-0.5	-0.5	0.7	0.9	0.4	1.0	-0.6	-0.5	-0.6	1.1	-1.1
Reaction time mean minus median AUC	0.0	0.1	0.3	-0.0	-0.1	0.2	0.1	-0.1	0.2	-0.1	0.0	-0.1	0.6	-0.5
Reaction time num false alarms	0.4	0.6	1.2	0.6	0.5	-0.5	-1.0	-1.0	-0.8	1.1	1.1	0.7	-0.5	0.8
Reaction time num false alarms AUC	0.2	0.5	1.2	0.5	0.5	-0.4	-0.7	-1.0	-0.6	1.1	1.0	0.6	-0.3	0.6
Reaction time trials correct on left	0.3	1.1	1.4	-1.1	-1.1	1.1	1.2	0.8	1.2	-1.0	-1.1	-1.1	1.1	-0.9
Reaction time trials on left	0.3	1.1	1.4	-1.1	-1.1	1.1	1.2	0.8	1.2	-1.0	-1.0	-1.0	1.0	-0.9
Reaction time mean	0.2	0.4	0.7	0.8	0.8	-0.8	0.1	-0.4	-0.3	0.8	0.7	0.7	-0.7	0.4
Reaction time mean AUC	0.2	0.4	0.7	0.8	0.8	-0.8	0.1	-0.4	-0.3	0.7	0.7	0.7	-0.8	0.5
Median of all reaction times	1.0	1.6	2.3	1.4	1.5	-1.5	-0.5	-0.9	-1.0	1.4	1.4	1.3	-1.5	1.2
Reaction time omissions	0.4	0.6	1.2	0.9	0.9	-0.8	-0.0	-0.8	-0.6	1.1	1.1	0.7	-0.7	0.7
Reaction time false alarm rate	1.0	1.3	2.1	1.0	1.0	-0.9	-1.2	-1.3	-1.2	1.4	1.4	1.1	-0.8	1.1
Reaction time premature initiation rate	0.5	0.8	2.4	0.5	0.6	-0.8	-0.3	-0.1	-0.3	0.9	1.0	0.9	-1.5	1.4
Reaction time premature initiations	0.1	0.2	0.4	-0.3	-0.3	0.2	0.6	0.6	0.6	-0.0	0.0	-0.0	-0.6	0.5
Std. dev. reaction times	0.0	0.0	0.2	0.1	0.1	-0.0	0.4	-0.1	0.3	0.1	0.2	0.1	0.3	-0.3
Reaction time trials completed	0.3	1.1	1.4	-1.1	-1.1	1.1	1.2	0.8	1.2	-1.0	-1.0	-1.0	1.0	-0.9
Reaction time trials AUC	0.3	1.0	1.5	-1.0	-1.0	1.0	1.1	0.7	1.2	-1.0	-1.0	-1.0	1.1	-1.0
Run reversals in cocaine runway, females	1.5	1.7	3.4	-1.3	-1.2	1.1	1.1	1.9	1.8	-1.2	-1.4	-1.4	0.6	-1.1
Run reversals in cocaine runway, males	0.2	0.2	0.4	0.4	0.4	-0.4	-0.6	-0.3	-0.6	0.5	0.3	0.3	-0.3	0.3
Latency to leave start box in cocaine runway	1.1	1.5	2.5	-1.2	-1.1	1.1	1.6	1.1	1.1	-1.1	-1.3	-1.4	1.3	-1.4
Latency to leave start box in cocaine runway, F	1.8	2.3	3.4	-1.6	-1.5	1.5	1.8	1.6	1.5	-1.3	-1.5	-1.5	1.3	-1.4
Latency to leave start box in cocaine runway, M	0.1	0.1	0.4	0.5	0.5	-0.5	-0.1	-0.6	-0.4	0.3	0.2	0.1	-0.1	-0.0
Std. dev. time between licks in bursts	0.0	0.1	0.2	-0.2	-0.3	0.4	0.4	-0.1	0.1	-0.1	-0.2	-0.0	0.4	-0.2
Total sessions with >9 infusions	0.1	0.2	0.4	0.4	0.5	-0.6	-0.3	-0.0	-0.4	0.5	0.4	0.4	-0.6	0.2
Short access day 1 total inactive lever presses	1.1	2.1	3.3	1.5	1.5	-1.6	-1.3	-1.3	-1.4	1.8	1.6	1.3	-1.4	1.2
Short access day 10 total inactive lever presses	0.0	0.1	1.0	0.2	0.2	-0.2	1.0	-0.2	0.1	0.5	0.4	0.3	0.0	-0.1
Short access day 1 total infusions	0.2	0.4	1.4	0.5	0.6	-0.8	-0.6	0.1	-0.7	0.6	0.5	0.5	-1.2	0.7
Short access day 10 total infusions	0.3	0.5	0.7	0.6	0.6	-0.7	-0.8	-0.4	-0.8	0.8	0.7	0.6	-0.7	0.6
Short access total infusions	0.3	0.4	1.1	0.5	0.6	-0.7	-0.5	-0.1	-0.5	0.8	0.6	0.6	-1.1	0.8
Short access day 1 locomotion	0.7	1.2	1.9	1.1	1.1	-1.2	-1.1	-0.8	-1.2	1.2	1.1	1.0	-1.4	1.1
Short access day 10 total locomotion	0.5	2.0	3.1	1.5	1.4	-1.4	-1.8	-1.8	-1.5	1.4	1.5	1.3	-0.8	1.0
Short access total locomotion	0.2	0.3	0.5	0.6	0.6	-0.6	-0.7	-0.6	-0.5	0.6	0.6	0.4	-0.3	0.3
One hour access (0.3 mA shock)	0.2	0.3	0.9	-0.5	-0.4	0.4	0.4	0.5	1.0	-0.5	-0.5	-0.3	0.4	-0.5
Compulsive drug intake	0.1	0.2	0.8	-0.1	-0.1	0.1	-0.1	0.5	0.5	-0.6	-0.6	-0.3	0.4	-0.9
One hour access (shock baseline)	0.0	0.0	0.1	-0.1	-0.1	-0.0	0.3	0.2	0.1	0.1	0.1	0.1	-0.4	0.4
Social response proportion	0.4	0.5	0.7	-0.8	-0.8	0.7	-0.1	0.8	0.8	-0.7	-0.8	-0.9	0.5	-0.5
Social responses	0.1	0.1	1.0	-0.2	-0.2	0.1	-1.0	-0.1	-0.3	-0.1	-0.0	0.0	-0.1	0.4
Social time	0.1	0.1	0.3	-0.5	-0.5	0.6	-0.2	-0.0	0.2	-0.1	-0.0	-0.1	0.5	-0.1
Soleus weight	0.1	0.2	0.5	-0.6	-0.7	0.7	-0.4	0.0	0.2	-0.2	-0.2	-0.1	0.4	0.1
Bone: stiffness	0.0	0.1	0.3	-0.4	-0.3	0.2	-0.1	0.4	-0.1	-0.1	-0.1	-0.0	-0.5	0.5
Tibialis anterior weight	1.7	5.8	7.3	-2.7	-2.7	2.6	2.4	2.6	2.3	-2.4	-2.4	-2.3	2.0	-1.9
Time to tail flick, vehicle, before self-admin	0.1	0.2	0.5	0.2	0.1	0.1	-0.3	-0.6	-0.6	0.3	0.1	0.0	0.7	-0.5
Time to tail flick, vehicle, after self-admin	0.0	0.1	0.2	0.2	0.1	-0.0	-0.2	-0.5	0.0	0.1	0.2	0.5	0.0	0.3
Time to tail flick, test, before self-admin	0.9	1.0	1.3	-1.1	-1.1	1.1	1.0	1.1	1.1	-1.0	-0.9	-0.9	0.9	-0.8
Time to tail flick, test, after self-admin	0.2	0.2	0.8	0.1	0.0	0.1	-0.9	-0.6	-0.7	0.4	0.2	-0.0	0.5	-0.1
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	1.0	0.4	0.4	-0.4	-0.7	-0.7	-0.3	0.5	0.7	0.8	-0.7	1.0
Delta time to tail flick, test, before/after SA	2.0	2.5	4.7	1.6	1.5	-1.5	-2.2	-1.9	-1.8	1.8	1.4	1.2	-0.9	1.1
Tibia length	1.8	5.0	7.4	-2.7	-2.7	2.6	1.6	2.4	1.9	-2.1	-2.2	-2.2	2.0	-1.7
Ambulatory time before self-admin	0.0	0.0	0.1	0.1	0.1	-0.2	0.3	-0.1	-0.2	0.2	0.2	0.3	-0.3	0.3
Ambulatory time after self-admin	1.1	1.7	2.5	-1.6	-1.5	1.5	1.5	1.6	0.7	-1.3	-1.3	-1.1	1.0	-0.9
Bone: tissue strength	1.5	1.5	2.3	-1.1	-1.1	1.2	1.1	0.9	1.2	-1.3	-1.3	-1.3	1.5	-1.5
Total heroin consumption	2.7	3.2	4.4	1.6	1.6	-1.5	-1.5	-2.0	-1.6	2.1	2.0	1.8	-1.7	2.1
Bone: trabecular number	4.7	8.9	10.5	2.7	2.7	-2.8	-3.1	-2.9	-3.0	3.2	3.2	3.0	-3.0	3.2
Bone: trabecular spacing	1.9	2.7	3.7	-1.9	-1.9	1.9	1.4	1.7	1.5	-1.5	-1.6	-1.5	1.6	-1.4
Bone: trabecular thickness	0.1	0.1	0.3	0.3	0.3	-0.2	-0.1	-0.5	-0.4	0.4	0.4	0.3	-0.1	0.2
Bone: trabecular tissue density	0.1	0.1	0.4	0.2	0.3	-0.3	0.2	0.2	0.6	-0.4	-0.4	-0.3	-0.0	-0.5
Water consumed over 24 hours	0.1	0.2	0.5	-0.4	-0.4	0.5	0.3	0.1	0.2	-0.4	-0.3	-0.4	0.7	-0.6
Number of responses in last shaping day	0.2	0.3	0.7	0.7	0.7	-0.7	-0.5	-0.4	-0.8	0.6	0.6	0.4	-0.3	-0.0