Hub : Genes

Ralgdsl2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Ralgdsl2 0.05 0.03 4.1e-03 0.02 0.02 0.03 0.03 1.2e-02 1.0e-02 3.5e-03 1.7e-03
2 Brain alternative TSS NM_212547.3 0.03 0.02 8.6e-03 0.02 0.02 0.01 0.02 6.7e-03 2.9e-03 2.0e-02 4.7e-03
3 Liver intron excision ratio chr20_4956389_4957658 0.11 0.07 4.0e-03 0 0 0 -0 2.2e-01 1.5e-01 3.5e-01 4.7e-01
4 NAcc mRNA stability Ralgdsl2 0.04 0.03 3.5e-03 0.01 0 -0 0 1.7e-02 2.0e-01 5.0e-01 7.2e-02
5 IC gene expression Ralgdsl2 0.25 0.11 1.7e-06 0.16 0.14 0.13 0.15 4.5e-07 1.8e-06 4.2e-06 7.3e-07
6 pVTA gene expression Ralgdsl2 0.11 0.06 5.4e-06 0.08 0.05 0.07 0.06 5.0e-07 3.9e-05 2.1e-06 5.9e-06
7 Adipose mRNA stability Ralgdsl2 0.12 0.06 2.5e-10 0.1 0.11 0.1 0.11 1.2e-11 3.8e-12 1.5e-11 5.4e-12
8 NAcc alternative TSS NM_212547.3 0.03 0.02 2.5e-04 0.01 0.02 0.02 0.02 7.8e-03 3.4e-04 1.7e-04 9.0e-04
9 Brain alternative TSS XM_063279024.1 0.04 0.02 1.0e-03 0.03 0.03 0.04 0.03 9.1e-04 1.4e-03 2.5e-04 7.1e-04
10 Brain alternative TSS XM_063279024.1 0.03 0.02 1.5e-03 0.03 0.03 0.03 0.03 1.6e-03 2.0e-03 8.5e-04 1.3e-03
11 Brain isoform ratio XM_063279024.1 0.04 0.02 9.6e-04 0.02 0.03 0.03 0.03 3.3e-03 1.8e-03 6.3e-04 1.9e-03
12 NAcc alternative TSS NM_212547.3 0.03 0.02 2.3e-04 0.02 0.02 0.03 0.03 6.0e-04 1.4e-04 6.7e-06 8.1e-05
13 Liver gene expression Ralgdsl2 0.34 0.12 0.0e+00 0.29 0.32 0.33 0.33 9.9e-33 4.6e-36 2.1e-37 2.3e-37
14 LHb intron excision ratio chr20_4952978_4954068 0.39 0.17 8.6e-03 0 0 0.02 0.05 3.2e-01 3.0e-01 1.3e-01 2.6e-02
15 Brain mRNA stability Ralgdsl2 0.15 0.07 2.4e-10 0.1 0.1 0.11 0.1 3.1e-09 7.8e-10 3.6e-10 4.9e-10
16 LHb gene expression Ralgdsl2 0.25 0.14 1.5e-03 0.14 0.06 0.11 0.1 2.8e-04 1.6e-02 1.2e-03 2.6e-03
17 NAcc isoform ratio NM_212547.3 0.03 0.02 2.2e-04 0.01 0.02 0.01 0.01 1.3e-02 1.2e-03 7.4e-03 8.2e-03
18 NAcc isoform ratio XM_063279024.1 0.03 0.02 6.8e-05 0.01 0.03 0.02 0.02 3.5e-03 7.3e-05 8.6e-04 7.1e-04
19 IC isoform ratio XM_063279023.1 0.07 0.04 9.9e-03 0.01 0.02 0.02 0.01 9.8e-02 3.9e-02 3.2e-02 1.8e-01
20 Brain isoform ratio NM_212547.3 0.05 0.03 4.1e-04 0.05 0.03 0.04 0.04 1.3e-05 5.4e-04 1.1e-04 4.3e-05
21 NAcc alternative TSS XM_063279024.1 0.03 0.02 2.5e-05 0.02 0.03 0.02 0.02 2.0e-04 2.8e-05 5.7e-04 7.6e-04
22 NAcc alternative TSS XM_063279024.1 0.04 0.02 4.1e-06 0.03 0.04 0.02 0.03 2.2e-05 2.9e-06 1.6e-04 7.1e-05
23 BLA gene expression Ralgdsl2 0.14 0.09 4.3e-03 0.05 0.04 0.04 0.04 1.5e-03 3.5e-03 3.8e-03 3.3e-03
24 Brain gene expression Ralgdsl2 0.13 0.06 3.6e-08 0.06 0.09 0.08 0.08 1.2e-06 1.3e-08 5.5e-08 5.9e-08
25 PL gene expression Ralgdsl2 0.07 0.04 3.9e-04 0.03 0.03 0.03 0.03 3.8e-04 2.0e-04 1.8e-04 3.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density2.14.06.8-1.9-2.11.62.62.42.1-2.52.4-1.7-1.7-1.82.22.0-1.82.22.2-2.01.80.21.91.61.72.2-2.31.6
Area under the delay curve0.30.51.90.41.0-0.7-0.8-0.8-0.71.2-0.50.60.50.50.0-0.90.6-0.6-1.40.5-0.4-0.7-0.3-0.2-0.3-0.60.6-1.1
BMI with tail0.82.88.11.91.2-1.9-1.3-1.3-1.31.1-1.42.22.12.0-1.5-1.1-1.7-1.3-1.11.8-2.12.8-1.1-2.3-2.3-1.70.7-0.6
BMI without tail1.15.89.32.42.8-3.0-2.5-2.5-2.72.6-1.92.92.92.8-1.5-2.6-0.3-2.4-2.12.5-2.62.4-2.4-2.6-2.6-2.71.4-1.3
Body weight3.213.918.34.33.6-3.6-4.0-4.1-4.14.1-2.84.04.04.0-3.1-3.70.8-3.9-3.74.2-4.22.1-3.8-4.1-4.1-3.93.5-3.4
Weight adjusted by age1.54.39.02.51.8-1.3-2.8-3.0-2.22.3-1.51.91.82.0-1.9-2.10.7-2.3-2.71.8-1.6-0.5-2.1-1.4-1.5-2.52.4-2.6
Bone surface0.10.21.1-0.3-0.40.50.80.60.4-0.40.5-0.6-0.5-0.50.20.11.1-0.00.30.1-0.1-0.6-0.0-0.1-0.10.80.20.0
Bone volume0.30.51.5-0.6-0.70.51.21.10.8-0.91.0-0.6-0.6-0.70.90.6-0.20.70.7-0.50.4-0.10.60.30.31.1-0.70.5
Breakpoint value in progressive ratio session0.10.21.0-1.0-0.50.40.60.50.6-0.50.3-0.6-0.6-0.50.30.40.50.30.5-0.20.3-0.10.30.20.30.6-0.20.7
Number of licking bursts0.10.42.4-0.5-0.60.80.40.50.4-0.2-0.4-0.9-0.9-0.7-0.40.41.50.20.60.10.0-0.80.20.10.10.90.60.4
Context. condit. distance diff. score5.76.911.8-3.0-3.33.42.92.92.8-2.52.7-3.3-3.3-3.22.22.90.62.52.7-2.12.2-2.62.92.32.22.9-0.91.0
Locomotion velocity, session 11.21.33.0-1.3-0.91.30.70.80.9-0.71.7-1.3-1.3-1.21.70.60.70.70.8-1.31.5-1.61.11.61.61.1-0.50.2
Locomotion distance, session 11.72.23.7-1.6-1.61.31.71.71.6-1.90.8-1.4-1.4-1.41.01.5-1.11.61.9-1.51.4-0.01.61.31.31.6-1.61.7
Locomotion velocity, session 20.40.51.5-0.9-0.70.70.80.90.8-0.70.6-0.9-0.9-0.90.70.50.50.80.9-0.40.5-0.50.50.50.41.2-0.40.5
Locomotion distance, session 21.01.52.9-1.0-1.71.51.21.21.3-1.60.7-1.3-1.3-1.30.71.4-0.81.41.5-1.21.2-0.61.31.11.11.3-0.90.9
Locomotion velocity, session 30.10.21.10.00.4-0.6-0.10.20.2-0.0-1.00.20.20.1-0.50.1-0.40.2-0.10.0-0.10.70.4-0.2-0.10.2-0.70.8
Locomotion distance, session 32.22.53.7-1.9-1.61.41.61.81.9-1.90.9-1.6-1.6-1.71.21.7-1.11.91.7-1.71.6-0.31.91.51.51.7-1.81.4
Stereotopy head waving bouts, day 32.12.54.11.71.4-0.9-2.0-1.7-1.91.7-1.71.11.11.3-1.9-1.71.7-1.8-1.71.7-1.5-0.2-1.6-1.3-1.4-1.32.0-1.7
Stereotopy head waving duration, day 31.62.04.01.61.6-1.1-2.0-1.7-1.61.9-1.51.21.21.2-1.4-1.61.5-1.6-1.71.4-1.2-0.3-1.2-1.0-1.0-1.31.6-1.3
Locomotion velocity, session 75.76.29.6-2.2-3.12.82.52.72.8-2.92.4-2.4-2.5-2.62.13.0-1.92.72.4-2.72.6-1.32.92.52.42.5-2.11.2
Locomotion distance, session 76.48.211.0-2.9-3.13.02.62.93.1-3.22.7-2.8-2.8-2.92.93.2-1.73.12.9-3.33.2-1.63.23.23.22.6-2.72.0
Stereotopy head waving bouts, day 70.20.31.3-0.11.2-1.0-0.6-0.4-0.21.0-0.70.40.40.40.0-0.70.5-0.2-0.20.3-0.20.6-0.0-0.1-0.0-0.2-0.10.5
Stereotopy head waving duration, day 70.70.82.10.61.4-1.3-1.1-1.0-0.81.3-1.30.90.90.9-0.8-1.10.6-0.9-0.70.8-0.80.9-0.7-0.7-0.7-0.70.5-0.1
Locomotion velocity, session 81.01.26.5-1.0-1.01.50.50.80.6-0.10.8-1.5-1.5-1.30.40.42.50.20.2-0.10.5-2.50.50.70.61.11.0-0.3
Locomotion distance, session 85.27.514.0-3.0-3.73.73.03.13.1-3.02.4-3.3-3.3-3.21.93.2-0.02.73.0-2.32.3-2.22.92.32.23.0-1.11.3
Degree of sensitization distance0.20.21.0-0.2-0.30.60.0-0.0-0.10.00.8-0.4-0.3-0.20.40.01.0-0.4-0.00.10.1-0.9-0.20.20.1-0.10.8-0.6
Degree of sensitization stereotypy0.40.52.0-1.10.2-0.30.70.70.9-0.00.1-0.4-0.4-0.50.90.30.00.70.9-0.50.60.30.80.60.60.8-1.11.4
Conditioned locomotion0.60.71.80.90.3-0.4-0.3-0.6-0.70.7-0.70.60.60.6-1.2-0.61.1-0.9-0.91.3-1.30.2-0.8-1.3-1.4-0.31.3-0.8
Cocaine response after cond. corrected0.20.31.3-0.0-1.10.90.60.30.4-0.8-0.4-0.5-0.5-0.4-0.80.9-0.60.30.70.0-0.10.20.3-0.2-0.20.40.30.1
Cocaine response after cond. not corrected0.50.72.30.80.2-0.1-0.6-0.7-0.80.6-1.20.30.40.5-1.5-0.40.8-0.9-0.41.2-1.10.1-0.9-1.1-1.1-0.51.4-0.6
Cocaine response before conditioning4.45.38.82.12.9-2.4-2.6-2.4-2.63.0-1.91.92.02.1-1.7-3.02.6-2.7-2.42.4-2.20.1-2.6-2.0-2.0-2.12.2-1.8
Saline control response3.44.69.42.22.9-3.1-2.3-2.1-2.32.3-1.53.02.92.8-1.2-2.4-0.7-2.0-2.11.5-1.72.6-2.1-1.7-1.6-2.40.5-1.4
Bone: connectivity density1.52.35.2-1.3-2.01.72.21.71.5-2.12.3-1.5-1.5-1.51.71.6-0.91.51.6-1.41.3-0.21.31.11.11.8-1.30.7
Bone: cortical apparent density0.91.54.01.31.3-1.6-1.0-1.0-0.80.7-1.21.61.61.5-1.2-1.1-1.4-0.8-0.91.0-1.32.0-1.1-1.4-1.3-0.90.1-0.4
Bone: cortical area0.10.20.40.10.5-0.5-0.0-0.1-0.10.60.00.30.30.30.1-0.50.4-0.3-0.50.6-0.60.1-0.4-0.6-0.6-0.20.4-0.3
Bone: cortical porosity0.30.41.5-1.10.9-0.5-0.6-0.20.20.70.3-0.1-0.1-0.11.2-0.50.70.2-0.1-0.60.8-0.80.20.91.0-0.1-0.60.3
Bone: cortical porosity0.40.52.0-1.00.7-0.2-0.7-0.30.10.80.7-0.2-0.2-0.21.4-0.61.30.0-0.2-0.50.7-1.3-0.01.00.9-0.2-0.1-0.3
Bone: cortical thickness0.40.63.70.10.8-1.30.20.20.10.2-0.20.90.80.60.2-0.4-1.80.2-0.20.3-0.61.9-0.1-0.7-0.7-0.1-1.01.1
Bone: cortical thickness1.11.46.10.91.3-1.8-0.5-0.3-0.60.5-1.01.61.51.4-0.8-1.2-1.7-0.6-0.90.9-1.22.5-0.9-1.4-1.3-0.7-0.40.4
Bone: cortical tissue density0.91.53.41.31.3-1.6-1.1-1.1-0.80.8-1.21.61.61.5-1.2-1.2-1.2-0.9-1.01.1-1.31.8-1.1-1.4-1.3-1.00.2-0.5
Condit. Reinf. active minus inactive responses0.40.52.2-0.6-0.10.40.30.00.1-0.31.5-0.4-0.4-0.31.5-0.00.20.30.3-1.01.1-0.60.11.11.20.3-0.60.1
Condit. Reinf. active-inactive response ratio0.50.51.20.41.0-1.0-0.7-1.0-0.70.60.21.00.91.00.2-1.1-0.1-0.7-0.70.3-0.30.9-1.1-0.3-0.2-0.80.1-0.6
Condit. Reinf. active responses0.50.73.4-0.6-0.60.70.60.40.3-0.81.8-0.5-0.5-0.41.60.4-0.40.60.6-1.21.2-0.30.31.21.20.3-0.80.1
Condit. Reinf. inactive responses1.82.43.9-1.3-1.61.31.71.81.4-2.01.9-1.3-1.3-1.31.81.7-1.61.71.6-1.81.6-0.21.51.51.51.2-1.81.0
Incentive salience index mean1.62.15.6-1.5-1.51.71.41.21.1-1.22.4-1.6-1.6-1.52.11.20.71.31.2-1.41.5-1.61.11.61.61.4-0.60.5
Condit. Reinf. lever presses3.24.89.2-2.2-3.03.02.32.22.1-2.22.8-2.7-2.7-2.62.12.50.82.12.1-1.71.8-2.22.01.81.72.4-0.60.8
Condit. Reinf. active minus inactive responses0.61.01.90.71.3-1.0-1.2-1.0-1.11.4-0.10.80.80.90.0-1.31.3-1.2-1.30.9-0.8-0.4-1.2-0.6-0.6-1.30.9-0.7
Condit. Reinf. active-inactive response ratio0.91.42.91.01.3-0.8-1.5-1.4-1.51.70.40.80.81.00.2-1.41.6-1.5-1.61.1-0.8-0.7-1.3-0.6-0.7-1.61.5-1.3
Condit. Reinf. active responses0.10.20.60.20.7-0.5-0.6-0.5-0.30.50.00.30.30.30.1-0.50.8-0.6-0.60.2-0.2-0.3-0.6-0.1-0.1-0.60.2-0.0
Condit. Reinf. inactive responses0.10.10.5-0.00.2-0.50.10.10.3-0.3-0.70.20.20.1-0.5-0.0-0.40.10.1-0.0-0.10.7-0.1-0.2-0.20.2-0.60.7
Condit. Reinf. lever presses0.71.14.2-1.5-0.50.60.70.91.2-0.61.7-0.8-0.8-0.92.00.7-0.30.90.8-1.21.3-0.61.01.31.30.5-1.10.7
Condit. Reinf. lever reinforcers received0.10.10.8-0.10.6-0.4-0.4-0.3-0.20.40.40.20.20.20.5-0.50.9-0.5-0.40.1-0.0-0.3-0.60.00.1-0.50.10.1
Conditioned reinforcement - actives0.00.21.4-0.2-0.20.20.2-0.00.2-0.31.2-0.0-0.1-0.10.80.0-0.40.30.3-0.50.4-0.20.00.40.40.2-0.4-0.3
Conditioned reinforcement - inactives0.00.10.50.60.2-0.0-0.4-0.7-0.30.1-0.20.30.30.3-0.1-0.3-0.30.0-0.3-0.40.4-0.1-0.40.40.5-0.6-0.1-0.6
Conditioned locomotion0.20.32.20.0-0.30.5-0.0-0.10.1-0.11.5-0.1-0.2-0.21.10.1-0.10.1-0.2-0.60.6-1.00.20.70.7-0.00.0-0.9
Patch foraging indifference point 0 sec1.64.57.32.32.5-2.6-2.6-2.7-2.72.0-1.12.72.72.6-0.9-2.5-0.3-2.1-2.11.6-1.62.3-2.4-1.7-1.6-2.30.8-1.5
Patch foraging indifference point AUC0.30.61.70.61.1-0.8-0.9-1.0-1.20.8-0.10.50.50.6-0.1-1.11.3-1.0-0.40.8-0.60.1-1.3-0.6-0.6-0.40.6-0.2
Delay disc. indifference point, 0s delay0.10.11.2-0.0-0.10.4-0.2-0.2-0.10.40.1-0.1-0.1-0.10.2-0.20.6-0.2-0.50.1-0.0-1.1-0.10.10.00.10.6-0.7
Delay disc. indifference point, 16s delay0.10.10.90.20.6-0.60.00.1-0.20.4-0.90.40.40.2-0.3-0.3-0.50.2-0.7-0.10.10.20.30.10.1-0.3-0.40.1
Delay disc. indifference point, 2s delay1.11.23.80.51.1-0.5-1.7-1.6-1.21.60.10.60.60.70.2-1.31.6-1.3-1.70.7-0.4-1.3-0.9-0.2-0.3-0.91.4-2.0
Delay disc. indifference point, 24s delay0.71.12.51.11.6-1.2-1.3-1.4-1.31.6-1.11.21.21.1-0.6-1.50.4-0.9-1.50.4-0.3-0.1-0.8-0.1-0.1-1.50.6-1.0
Delay disc. indifference point, 4s delay1.81.93.41.01.8-1.5-1.6-1.6-1.51.8-1.11.21.21.2-0.9-1.71.2-1.6-1.71.4-1.3-0.2-1.4-1.2-1.2-1.11.3-1.6
Delay disc. indifference point, 8s delay0.10.21.00.10.5-0.3-0.4-0.4-0.30.70.10.30.20.20.6-0.40.1-0.1-1.0-0.00.1-0.80.20.20.1-0.40.2-0.7
Indifference point function ln k0.10.41.2-0.7-0.50.70.70.70.8-0.3-0.1-0.7-0.7-0.70.10.51.10.50.1-0.30.4-0.80.90.40.40.8-0.00.5
Indifference point function log k0.10.41.2-0.7-0.50.70.70.70.8-0.3-0.1-0.7-0.7-0.70.10.51.10.50.1-0.30.4-0.80.90.40.40.8-0.00.5
Patch foraging total patch changes 0 sec1.54.47.42.32.6-2.6-2.6-2.6-2.72.0-1.22.72.72.6-1.0-2.5-0.4-2.0-2.11.5-1.62.4-2.3-1.6-1.5-2.30.7-1.3
Patch foraging total patch changes 12 sec2.12.95.11.92.1-2.1-1.8-1.9-2.31.5-1.62.02.02.0-1.4-2.10.0-1.8-1.31.4-1.51.5-2.1-1.5-1.4-1.80.7-0.6
Patch foraging total patch changes 18 sec0.81.98.01.31.3-1.8-1.2-1.3-1.50.5-1.11.81.81.7-0.8-1.3-2.0-0.8-0.20.8-1.12.8-1.6-1.3-1.2-1.1-0.3-0.1
Patch foraging total patch changes 24 sec0.20.64.9-0.10.2-0.60.0-0.2-0.2-0.51.00.60.60.41.20.0-2.20.60.4-0.60.41.8-0.10.20.4-0.2-1.30.4
Patch foraging total patch changes 6 sec1.62.75.22.02.1-2.2-1.9-2.2-2.31.5-0.72.22.22.1-0.5-1.9-0.9-1.4-1.31.0-1.11.8-1.8-1.2-1.1-1.80.3-0.9
Patch foraging time to switch 0 sec0.10.54.70.4-0.5-0.00.30.30.4-0.5-0.90.40.30.2-1.20.5-2.20.40.20.2-0.51.10.3-0.7-0.7-0.4-0.10.1
Patch foraging water rate 0 sec0.31.02.61.31.0-0.7-1.6-1.5-1.51.1-0.51.00.91.0-0.6-1.00.4-1.0-1.20.8-0.70.1-1.2-0.6-0.6-1.01.0-1.1
Patch foraging water rate 12 sec0.10.31.5-0.3-0.2-0.10.30.40.5-0.6-0.0-0.0-0.1-0.20.30.5-1.00.70.4-0.40.30.90.50.20.20.9-1.11.2
Patch foraging water rate 18 sec0.20.50.90.70.8-0.8-0.8-0.7-0.40.7-0.50.90.90.9-0.5-0.5-0.4-0.4-1.00.6-0.61.0-0.5-0.7-0.6-0.60.3-0.5
Patch foraging water rate 24 sec0.10.20.70.30.4-0.5-0.3-0.2-0.00.0-0.80.40.40.4-0.6-0.3-0.3-0.2-0.20.3-0.40.6-0.6-0.4-0.4-0.0-0.30.3
Patch foraging water rate 6 sec0.20.31.70.50.3-0.5-0.5-0.3-0.40.0-1.30.50.50.5-1.1-0.1-0.4-0.3-0.40.4-0.50.9-0.5-0.6-0.50.0-0.10.6
Seeking ratio, delayed vs. immediate footshock1.82.65.61.02.2-2.2-1.5-1.4-1.81.4-1.61.51.51.6-1.3-2.00.9-1.8-1.01.9-1.91.5-2.4-1.9-1.9-1.20.80.3
Distance traveled before self-admin0.10.20.90.0-0.30.1-0.0-0.10.1-0.10.1-0.00.00.1-0.30.10.3-0.20.20.8-0.90.4-0.4-0.9-1.00.10.7-0.4
Distance traveled after self-admin1.42.44.11.41.6-1.6-1.4-1.5-1.41.5-1.41.41.41.5-1.6-1.61.1-1.8-1.22.0-2.01.4-1.8-2.0-2.0-1.11.5-0.9
Extensor digitorum longus weight0.00.21.1-0.1-0.60.7-0.20.10.20.10.5-0.5-0.5-0.50.20.50.50.10.00.1-0.0-1.10.10.1-0.00.40.6-0.5
Bone: elastic displacement0.20.20.7-0.40.4-0.40.0-0.10.10.10.30.30.30.20.7-0.1-0.80.20.0-0.70.60.20.30.70.7-0.2-0.80.4
Bone: elastic work0.10.10.40.10.6-0.6-0.3-0.4-0.20.70.20.50.50.40.3-0.5-0.3-0.3-0.50.2-0.20.2-0.2-0.1-0.1-0.40.00.1
Bone: endosteal estimation2.35.514.02.11.7-1.0-2.5-2.6-2.52.9-1.11.31.41.6-1.8-2.23.7-2.8-2.52.7-2.3-1.4-2.5-1.9-2.1-2.13.7-3.4
Bone: endosteal perimeter0.51.38.90.5-0.10.6-0.6-0.7-0.71.10.0-0.3-0.2-0.0-0.5-0.43.0-1.1-0.91.2-0.9-1.9-0.8-0.7-0.8-0.42.4-2.0
Epididymis fat weight1.15.633.82.11.6-3.1-0.7-1.1-1.00.1-1.93.13.02.6-1.5-0.9-5.4-0.3-0.61.1-1.95.8-1.1-2.5-2.2-2.0-1.60.7
Delta time in closed arm before/after self-admin0.30.30.80.50.3-0.2-0.8-0.6-0.40.60.30.40.40.50.1-0.60.4-0.9-0.80.6-0.6-0.4-0.6-0.5-0.6-0.50.8-0.9
Delta time in open arm before/after self-admin0.00.00.20.20.2-0.20.10.0-0.2-0.2-0.20.10.10.0-0.1-0.0-0.40.10.2-0.30.3-0.10.20.20.30.2-0.50.1
Diff in mean of infusions in LGA sessions1.52.75.0-1.8-2.11.92.02.02.2-1.91.3-1.8-1.8-1.81.22.1-0.61.91.7-1.31.3-0.81.91.21.21.4-1.01.0
Delay discount exponential model param0.40.62.0-0.4-1.10.80.90.90.8-1.30.5-0.6-0.6-0.50.01.0-0.80.71.4-0.50.40.70.50.20.30.7-0.61.1
Extinction: sum of active levers before priming0.10.21.1-0.4-0.60.80.10.20.3-0.30.3-0.7-0.6-0.50.00.31.00.10.2-0.10.2-1.00.10.30.30.20.5-0.2
Active lever presses in extinction session 60.60.63.2-0.9-0.50.40.10.10.5-0.41.6-0.1-0.2-0.21.80.3-0.90.60.1-1.01.0-0.20.61.01.0-0.1-0.80.0
Bone: final force2.13.44.82.01.8-2.0-1.7-1.6-1.91.7-1.02.22.22.1-1.3-1.9-0.7-1.8-1.82.0-2.12.2-2.1-2.2-2.2-2.01.3-1.5
Bone: final moment1.52.43.61.71.5-1.7-1.6-1.5-1.61.5-0.71.91.91.8-0.9-1.6-0.7-1.5-1.61.6-1.71.7-1.7-1.7-1.7-1.81.0-1.4
Food consumed during 24 hour testing period0.50.92.71.00.3-0.3-0.9-1.0-0.90.8-1.40.70.70.8-1.6-0.50.1-0.9-0.81.3-1.20.6-0.9-1.2-1.3-0.91.5-0.9
Glucose1.21.914.9-0.2-1.02.1-0.7-0.40.10.31.0-1.5-1.4-1.10.60.53.3-0.3-0.1-0.40.9-3.90.31.31.1-0.21.9-1.4
Heart weight2.23.66.81.82.3-1.7-2.2-2.4-2.42.6-0.41.81.71.8-0.2-2.41.6-2.3-2.61.5-1.3-0.7-1.9-1.0-1.1-2.51.8-2.4
Delay discount hyperbolic model param0.50.72.2-0.3-1.20.91.01.00.9-1.40.5-0.7-0.6-0.6-0.01.1-0.90.81.5-0.60.40.80.50.30.30.7-0.71.2
Intermittent access intake day 1-15 change0.00.20.70.10.6-0.6-0.3-0.4-0.40.4-0.80.30.40.4-0.7-0.50.5-0.20.20.5-0.50.6-0.5-0.5-0.5-0.00.10.6
Intermittent access intake escalation0.10.41.40.21.0-1.2-0.5-0.6-0.50.5-0.70.80.80.7-0.4-0.8-0.1-0.30.00.4-0.51.2-0.5-0.6-0.5-0.2-0.30.7
Intermittent access intake escalation 20.00.10.4-0.30.3-0.2-0.1-0.30.00.2-0.4-0.0-0.0-0.0-0.3-0.30.6-0.00.20.1-0.0-0.30.10.00.00.4-0.00.5
Intermitt. access day 1 inactive lever presses0.00.52.50.6-0.40.5-0.1-0.2-0.20.1-1.5-0.6-0.5-0.2-1.6-0.01.6-0.50.00.8-0.7-0.1-0.9-0.6-0.70.01.3-0.2
Intermitt. access day 15 inactive lever presses0.10.61.31.20.7-0.6-1.0-0.9-0.90.8-0.70.60.70.7-0.8-0.90.3-0.8-0.80.8-0.70.2-1.0-0.7-0.7-0.90.9-0.9
Intermitt. access escalation Index0.72.14.3-1.8-1.81.62.02.11.6-1.81.3-1.9-1.7-1.71.11.90.21.52.1-0.70.6-0.21.30.50.51.7-0.71.3
Intermittent access day 1 total infusions0.92.76.2-1.1-1.61.81.00.91.4-1.42.5-1.3-1.4-1.42.31.4-1.01.51.2-2.42.4-1.71.62.52.50.9-1.40.1
Intermittent access day 15 total infusions0.20.51.6-0.4-0.10.20.20.00.4-0.41.3-0.1-0.2-0.21.10.3-0.80.70.7-1.11.10.00.51.11.10.3-1.10.4
Intermittent access terminal intake (last 3 days)0.20.31.3-0.10.2-0.0-0.4-0.40.00.01.10.20.10.11.1-0.2-0.50.40.2-0.91.0-0.20.01.01.0-0.2-0.7-0.2
Intermittent access total infusions0.60.72.2-0.2-0.30.50.20.10.5-0.51.4-0.2-0.3-0.31.40.4-0.80.70.5-1.41.4-0.50.61.51.50.3-1.0-0.0
Intermittent access day 1 locomotion0.30.52.8-0.2-0.60.60.40.30.4-0.71.7-0.3-0.3-0.41.30.6-1.10.60.3-1.00.9-0.40.60.90.90.1-0.7-0.5
Intermittent access day 15 total locomotion0.20.91.81.11.1-1.0-1.2-1.3-1.11.10.31.21.11.1-0.2-1.1-0.2-1.0-1.00.8-0.80.4-0.9-0.8-0.8-1.10.7-1.2
Intermittent access total locomotion0.20.20.90.50.4-0.4-0.4-0.6-0.40.31.00.70.60.50.6-0.4-0.9-0.1-0.4-0.20.10.20.00.10.2-0.4-0.2-0.6
Intermittent access standard deviation0.63.04.72.22.0-2.1-1.8-2.0-1.81.7-1.82.02.12.0-1.7-1.8-0.1-1.5-1.91.5-1.51.5-2.0-1.6-1.5-1.70.9-1.1
Left kidney weight1.310.114.43.43.6-3.8-3.3-3.3-3.13.5-2.23.73.63.5-2.3-3.40.2-3.2-3.33.6-3.82.5-3.1-3.7-3.7-3.02.3-1.8
Right kidney weight1.410.114.43.63.2-3.4-3.4-3.2-3.23.3-2.73.53.53.4-3.0-3.10.1-3.3-3.13.6-3.82.7-3.2-3.8-3.8-2.92.5-2.1
Cocaine induced anxiety0.10.20.70.0-0.50.40.50.50.0-0.4-0.4-0.4-0.4-0.3-0.70.30.8-0.00.30.5-0.50.20.0-0.6-0.60.40.50.0
Post-drug Anxiety0.20.20.80.20.2-0.30.0-0.1-0.50.3-0.50.20.20.3-0.6-0.30.7-0.4-0.30.9-0.90.2-0.4-0.9-0.9-0.40.7-0.4
Baseline Anxiety0.20.30.80.20.7-0.6-0.6-0.6-0.60.8-0.20.60.60.60.0-0.7-0.1-0.4-0.60.3-0.3-0.4-0.5-0.3-0.3-0.90.4-0.7
Tail length1.910.017.73.03.6-2.6-3.7-3.8-4.04.2-2.02.52.52.7-2.0-3.93.6-3.8-3.23.3-2.9-0.8-3.7-2.5-2.6-3.13.7-2.9
Length with tail3.214.022.64.23.8-2.9-4.3-4.4-4.54.8-2.63.13.23.4-2.9-4.13.6-4.4-4.14.0-3.6-0.8-4.1-3.2-3.4-3.64.6-4.0
Length without tail1.79.215.43.92.2-2.0-3.4-3.4-3.13.3-2.52.72.72.8-3.3-2.71.5-3.3-3.43.5-3.40.4-2.9-3.3-3.4-2.93.9-3.5
Times rat made contact with spout0.60.73.2-0.80.1-0.40.60.80.7-0.60.30.0-0.0-0.21.00.3-1.61.00.8-1.10.90.90.60.80.90.7-1.81.3
Lifetime Intake0.40.52.2-0.0-0.20.4-0.1-0.20.2-0.31.5-0.1-0.1-0.11.30.1-0.70.40.1-1.21.2-0.40.31.31.30.0-0.7-0.5
Liver weight, left1.62.86.81.50.9-0.5-1.8-2.0-1.51.6-2.00.90.91.1-2.5-1.42.2-2.1-1.42.0-1.8-0.1-1.8-1.6-1.7-1.32.6-2.1
Liver weight, right1.32.310.31.30.7-0.1-1.4-1.5-1.51.7-0.20.50.60.8-0.9-1.43.2-1.9-1.61.6-1.3-1.0-1.4-1.0-1.2-1.02.7-2.6
Locomotor activity1.42.23.40.81.8-1.6-1.6-1.3-1.61.6-1.61.31.41.5-1.5-1.41.8-1.5-1.01.8-1.71.5-1.3-1.6-1.6-1.01.4-0.4
Locomotor testing distance0.51.22.90.81.0-0.9-1.1-1.0-1.31.0-1.60.80.90.9-1.7-0.61.3-1.0-0.51.5-1.41.3-0.7-1.4-1.3-0.81.20.0
Locomotor testing rearing0.51.83.81.41.0-0.9-1.4-1.2-1.71.1-1.61.01.11.2-2.0-1.01.2-1.5-1.01.6-1.60.8-1.4-1.5-1.6-1.11.6-1.0
Locomotion in novel chamber0.10.10.40.20.1-0.30.10.10.20.0-0.60.10.0-0.1-0.70.2-0.20.3-0.30.2-0.3-0.10.4-0.3-0.30.5-0.30.5
Locomotion in novel chamber post-restriction0.41.32.01.31.2-1.3-1.1-1.2-1.21.2-0.51.31.31.3-0.7-1.2-0.4-1.1-1.41.1-1.21.0-1.1-1.2-1.2-1.30.8-1.0
Fecal boli incidents, locomotor time 10.30.91.5-0.7-1.21.20.60.61.0-1.01.2-0.8-0.9-0.90.81.1-0.81.11.0-1.11.1-0.41.11.01.00.8-0.70.1
Change in fecal boli incidents, locomotor task2.22.44.61.41.3-0.9-1.7-1.5-1.81.6-1.61.01.01.2-1.8-1.51.9-2.0-1.51.8-1.60.0-1.9-1.4-1.5-1.52.2-1.6
Time >=10cm from walls, locomotor time 12.63.26.01.61.0-1.0-1.8-1.9-1.71.6-1.51.11.21.4-2.1-1.71.5-2.1-1.62.4-2.40.7-2.4-2.3-2.4-1.22.5-2.0
Bouts of movement, locomotor time 10.50.61.9-1.1-0.60.41.40.90.9-0.80.9-0.8-0.8-0.80.70.80.30.71.1-0.40.4-0.00.90.30.31.0-0.70.9
Total resting periods, locomotor time 10.40.51.2-1.0-0.60.51.10.70.7-0.60.9-0.8-0.8-0.80.60.60.40.71.0-0.40.4-0.20.70.30.30.9-0.50.5
Rest time, locomotor task time 10.20.41.3-0.7-0.40.50.40.40.8-0.20.9-0.7-0.7-0.70.80.50.70.30.4-0.30.4-0.90.50.50.41.1-0.20.2
Distance moved, locomotor task time 10.51.53.11.41.2-1.1-1.2-1.2-1.61.1-1.71.41.41.4-1.6-1.1-0.1-1.1-1.21.0-1.01.1-1.1-1.0-1.0-1.81.0-0.9
Vertical activity count, locomotor time 10.42.75.41.91.6-1.7-1.5-1.7-2.01.4-1.42.12.12.1-1.5-1.5-0.5-1.6-1.61.4-1.51.9-1.4-1.5-1.5-2.31.2-1.3
Time >=10cm from walls, locomotor time 21.54.28.42.31.7-1.2-2.9-2.7-2.52.3-1.81.71.71.8-2.1-2.11.1-2.2-2.41.9-1.7-0.0-2.3-1.5-1.6-2.32.6-2.7
Bouts of movement, locomotor time 20.00.10.50.10.7-0.6-0.1-0.0-0.30.50.20.10.10.2-0.1-0.50.7-0.3-0.30.4-0.40.2-0.5-0.3-0.30.10.10.1
Total resting periods, locomotor time 20.00.21.5-0.50.5-0.30.20.2-0.10.40.6-0.3-0.2-0.10.4-0.41.2-0.2-0.10.3-0.1-0.4-0.2-0.1-0.10.50.10.1
Rest time, locomotor task time 20.40.71.9-1.0-1.11.11.00.90.9-0.60.8-1.2-1.2-1.10.30.81.30.30.80.2-0.1-1.00.4-0.1-0.11.40.5-0.0
Distance moved, locomotor task time 21.21.74.61.91.2-1.1-1.6-1.6-1.61.1-1.21.71.71.6-1.2-1.0-1.4-0.9-1.50.4-0.50.9-0.8-0.5-0.5-2.10.6-1.1
Vertical activity count, locomotor time 20.81.95.12.01.3-1.1-1.8-1.9-1.71.3-1.01.71.71.7-1.0-1.2-0.9-1.2-1.70.7-0.70.6-1.0-0.7-0.6-2.31.0-1.5
Light reinforcement 10.41.98.51.80.6-0.9-1.0-0.7-1.40.4-2.51.11.11.2-2.9-0.4-0.1-1.0-0.41.6-1.71.6-1.2-1.9-1.9-0.81.1-0.5
Light reinforcement 20.40.94.11.50.2-0.3-0.6-0.6-1.10.5-1.60.60.60.7-2.0-0.1-0.0-0.8-0.41.1-1.10.4-0.9-1.1-1.2-0.61.2-1.0
Bone: marrow area2.56.114.62.31.9-1.1-2.6-2.7-2.63.1-1.21.51.61.8-1.9-2.43.6-3.0-2.72.8-2.4-1.3-2.6-2.1-2.2-2.33.8-3.5
Bone: maximum diameter0.30.65.4-0.3-0.50.90.40.10.10.30.3-0.8-0.8-0.60.10.12.3-0.2-0.20.3-0.0-2.00.00.20.00.41.2-1.1
Bone: maximum force0.81.62.21.41.2-1.3-1.3-1.2-1.21.2-0.41.41.41.4-0.8-1.4-0.3-1.3-1.51.4-1.51.0-1.4-1.5-1.5-1.31.0-1.0
Bone: maximum moment0.51.01.71.21.0-1.0-1.2-1.1-1.01.1-0.11.11.11.1-0.4-1.1-0.3-1.1-1.31.0-1.10.5-1.1-1.0-1.0-1.20.9-0.9
Mean time between licks in bursts0.21.34.8-1.1-1.21.70.60.60.9-0.60.5-1.8-1.7-1.60.40.72.10.50.6-0.40.7-2.20.90.80.71.40.50.0
Mean num. licks in bursts0.20.54.40.20.8-1.1-0.2-0.1-0.1-0.00.30.90.90.70.7-0.3-2.10.3-0.2-0.50.31.3-0.00.20.3-0.5-1.40.4
Cd content in liver0.30.33.00.7-0.90.80.0-0.2-0.1-0.7-0.10.0-0.0-0.0-0.60.7-1.70.2-0.0-0.70.6-0.30.30.50.5-0.5-0.1-0.8
Co content in liver1.41.63.31.81.0-1.2-1.5-1.4-1.51.0-0.91.61.61.5-1.2-1.0-0.7-1.3-1.31.0-1.11.2-1.2-1.2-1.2-1.70.8-1.0
Cu content in liver0.80.93.1-1.1-0.3-0.11.00.91.1-1.10.4-0.2-0.2-0.40.90.9-1.71.11.1-1.00.80.91.00.70.80.5-1.81.7
Fe content in liver0.30.31.70.80.4-0.7-0.4-0.3-0.30.2-1.00.60.60.5-1.0-0.0-1.3-0.1-0.60.3-0.40.9-0.3-0.5-0.5-0.4-0.2-0.0
K content in liver1.71.63.7-1.6-1.41.31.11.61.9-1.40.5-1.4-1.4-1.40.51.6-0.31.41.6-1.00.9-0.71.40.90.91.5-1.01.6
Mg content in liver1.61.83.9-2.0-1.71.71.31.51.8-1.21.5-1.7-1.7-1.61.01.51.41.01.7-0.60.7-1.01.00.70.61.7-0.00.8
Mn content in liver1.01.16.5-0.6-1.31.60.20.41.0-0.30.9-1.4-1.3-1.20.10.92.60.20.70.10.1-2.40.60.30.10.91.1-0.7
Na content in liver0.30.32.2-0.70.2-0.50.30.80.6-0.3-1.0-0.2-0.1-0.2-0.30.3-0.70.60.4-0.1-0.00.90.2-0.1-0.10.3-0.91.5
Rb content in liver0.40.41.4-0.4-1.01.00.30.50.5-0.81.2-0.6-0.6-0.60.61.1-0.20.60.6-0.60.6-0.40.60.60.50.5-0.1-0.3
Se content in liver0.60.76.9-0.8-0.51.00.10.20.1-0.00.4-1.1-1.1-0.90.40.22.60.10.4-0.20.5-1.80.10.70.60.50.70.3
Sr content in liver0.20.20.60.6-0.20.4-0.5-0.6-0.60.3-0.50.0-0.00.0-0.7-0.00.0-0.1-0.5-0.00.1-0.8-0.10.20.1-0.40.6-0.8
Zn content in liver0.20.22.00.4-0.40.7-0.2-0.30.1-0.2-0.2-0.3-0.3-0.2-0.40.10.9-0.3-0.1-0.10.2-1.4-0.00.20.2-0.20.7-0.3
Bone: minimum diameter0.50.94.10.30.20.2-0.5-0.7-0.61.10.70.00.10.20.2-0.62.0-1.1-1.01.2-1.0-1.2-0.8-0.7-0.9-0.82.0-1.8
Time in familiar zone, hab. session 12.42.77.0-1.6-1.00.61.81.72.1-1.61.3-0.9-1.0-1.21.81.6-2.01.91.3-2.11.80.22.01.71.81.3-2.61.7
Time in novel zone, hab. session 12.63.06.01.91.3-0.9-1.8-1.7-2.21.8-2.01.11.21.4-2.3-1.71.7-2.0-1.52.0-1.8-0.1-1.9-1.7-1.7-1.42.4-1.7
Total zone transitions, hab. session 10.70.92.9-1.3-1.00.81.21.11.2-1.2-0.4-1.0-1.0-1.00.01.0-0.40.91.5-0.60.60.21.00.50.51.0-0.81.7
Total locomotion distance, hab. session 11.01.43.8-1.4-1.41.11.31.41.5-1.50.3-1.3-1.3-1.30.51.4-0.31.31.6-0.80.7-0.21.20.60.61.3-1.01.9
Locomotion velocity, hab. session 10.60.93.4-1.1-1.00.81.01.01.1-1.10.4-1.0-1.0-1.10.61.0-0.01.01.3-0.60.5-0.20.90.50.51.0-0.81.8
Time in familiar zone, hab. session 20.40.53.3-0.10.4-0.80.10.20.1-0.4-1.40.40.40.3-1.1-0.2-0.5-0.00.20.4-0.61.8-0.1-0.8-0.70.3-0.71.1
Time in novel zone, hab. session 20.40.52.41.00.4-0.0-0.9-0.9-1.00.90.50.40.40.50.3-0.60.2-0.6-0.9-0.10.2-1.1-0.50.40.4-0.70.7-1.5
Total zone transitions, hab. session 20.30.41.2-0.6-0.80.40.81.00.7-1.0-0.4-0.5-0.5-0.5-0.40.7-0.60.60.90.1-0.30.90.4-0.4-0.40.8-0.41.1
Total locomotion distance, hab. session 21.52.04.2-1.4-1.91.41.61.91.7-2.10.5-1.5-1.5-1.50.51.7-0.81.61.9-0.80.60.41.30.40.42.0-1.22.0
Locomotion velocity, hab. session 22.02.75.1-1.7-2.21.71.92.22.0-2.30.8-1.8-1.8-1.90.82.0-0.61.92.2-1.00.80.01.60.60.62.2-1.32.2
Novel to familiar place preference ratio0.10.10.5-0.1-0.10.3-0.3-0.2-0.0-0.1-0.3-0.2-0.2-0.20.00.1-0.00.20.3-0.60.6-0.50.10.70.70.1-0.20.1
Novelty place preference0.10.10.30.00.20.1-0.5-0.4-0.30.2-0.4-0.0-0.00.0-0.1-0.20.3-0.10.1-0.40.5-0.5-0.10.50.5-0.0-0.0-0.2
Time in novel zone, NPP test0.10.10.40.10.4-0.1-0.6-0.6-0.50.4-0.40.10.10.1-0.1-0.40.4-0.2-0.1-0.20.4-0.5-0.30.40.4-0.10.1-0.4
Total zone transitions, NPP test2.23.35.5-2.1-2.22.02.12.12.2-2.21.4-2.0-1.9-2.01.52.0-0.61.82.3-1.61.6-0.81.91.51.51.8-1.31.8
Total locomotion distance, NPP test2.53.56.1-1.7-2.52.22.01.92.0-2.32.3-1.8-1.8-1.92.02.2-1.32.02.2-1.81.6-0.72.01.51.51.7-1.41.4
Locomotion velocity, NPP test3.55.08.7-2.2-3.02.52.22.42.5-2.82.2-2.2-2.2-2.32.12.7-1.52.42.7-2.11.9-0.72.41.71.72.1-1.72.0
Intraocular pressure0.20.32.2-0.0-0.50.30.40.40.3-0.90.3-0.3-0.3-0.40.20.8-1.50.60.5-0.80.6-0.00.70.50.60.2-0.90.1
Delta distance traveled before/after self-admin2.02.24.71.42.2-1.8-1.7-1.7-1.61.9-1.51.61.61.6-1.1-2.00.9-1.7-1.91.2-1.10.8-1.5-0.9-0.9-1.51.0-0.8
Delta ambulatory time before/after self-admin1.32.24.41.32.1-1.7-1.6-1.7-1.61.9-1.41.51.51.6-1.1-2.01.2-1.8-1.71.4-1.20.7-1.7-1.1-1.1-1.41.2-0.9
Parametrial fat weight0.92.16.41.90.8-1.5-0.9-0.6-1.10.5-1.61.71.71.5-2.0-0.6-2.1-0.8-0.91.4-1.82.5-1.1-2.0-2.0-0.80.4-0.5
Pavlov. Cond. lever latency5.16.510.92.82.6-3.1-2.4-2.3-2.21.8-3.23.13.13.0-3.1-2.2-1.4-2.2-2.22.3-2.63.3-2.3-2.8-2.7-2.61.0-1.4
Pavlov. Cond. magazine entry latency1.62.04.3-2.0-1.01.31.41.31.1-0.71.6-1.8-1.8-1.71.80.81.61.21.3-1.21.5-2.11.11.61.61.5-0.61.0
Pavlov. Cond. change in total contacts0.60.62.5-1.1-0.30.70.50.40.3-0.01.6-0.8-0.8-0.71.60.11.30.30.4-0.60.8-1.20.30.90.90.4-0.00.1
Pavlov. Cond. index score3.74.78.7-2.7-2.02.42.12.11.9-1.32.8-2.6-2.7-2.52.81.71.61.91.8-1.82.1-3.01.92.32.22.1-0.81.2
Pavlov. Cond. latency score3.94.98.8-2.8-2.02.52.22.11.9-1.32.9-2.7-2.7-2.62.91.81.61.91.9-1.92.1-3.02.02.32.22.2-0.81.3
Pavlov. Cond. lever contacts4.15.09.2-2.5-2.52.92.02.01.9-1.63.0-2.8-2.8-2.62.82.11.21.92.0-1.92.2-3.02.02.32.22.1-0.50.9
Pavlov. Cond. magazine entry number1.21.63.31.70.9-1.2-1.2-1.2-1.00.7-1.41.61.61.5-1.5-0.7-1.2-1.1-1.21.1-1.31.8-0.9-1.4-1.4-1.30.6-1.0
Pavlov. Cond. intertrial magazine entries0.30.43.20.9-0.0-0.3-0.3-0.5-0.5-0.5-0.60.70.70.6-0.60.0-1.8-0.2-0.1-0.40.21.5-0.30.00.1-0.6-0.6-0.3
Pavlov. Cond. lever-magazine prob. diff.3.94.88.6-2.7-2.02.42.22.12.0-1.32.7-2.6-2.7-2.62.81.81.42.01.9-1.92.2-2.92.02.42.32.2-0.91.3
Pavlov. Cond. response bias2.32.86.2-2.0-1.62.01.51.51.3-1.12.0-2.2-2.2-2.11.91.21.41.41.6-1.51.7-2.51.31.91.81.7-0.60.9
Pavlov. Cond. lever latency0.50.62.00.90.10.1-0.7-0.6-0.90.4-0.90.20.30.4-1.3-0.61.3-0.8-0.61.0-0.9-0.3-0.9-0.9-0.9-0.51.4-1.0
Pavlov. Cond. magazine entry latency0.40.51.6-0.8-0.60.80.40.40.7-0.21.3-0.7-0.7-0.71.20.6-0.10.50.4-0.80.9-1.10.71.00.90.4-0.2-0.2
Pavlov. Cond. change in total contacts0.10.31.9-0.80.4-0.30.30.20.50.21.00.0-0.0-0.11.4-0.0-0.30.30.1-0.50.50.10.30.60.60.1-0.70.5
Pavlov. Cond. index score0.30.52.0-1.0-0.20.30.60.60.9-0.11.3-0.5-0.5-0.51.40.4-0.50.60.4-0.80.9-0.50.70.90.90.4-0.80.3
Pavlov. Cond. latency score0.20.31.4-0.8-0.00.10.50.40.7-0.01.0-0.3-0.3-0.41.20.3-0.50.40.2-0.70.7-0.40.60.70.70.3-0.70.2
Pavlov. Cond. lever contacts0.30.51.6-0.8-0.0-0.10.50.50.8-0.30.7-0.1-0.2-0.31.10.5-1.30.70.6-0.80.70.40.70.70.70.3-1.20.8
Pavlov. Cond. magazine entry number0.20.20.90.50.4-0.4-0.3-0.3-0.50.1-0.90.30.40.4-0.8-0.50.6-0.4-0.30.5-0.50.4-0.5-0.6-0.6-0.30.30.1
Pavlov. Cond. intertrial magazine entries0.10.34.0-0.4-0.30.50.30.40.0-0.5-0.2-0.8-0.7-0.6-0.2-0.02.00.00.50.1-0.0-0.7-0.0-0.0-0.00.60.20.7
Pavlov. Cond. lever-magazine prob. diff.0.30.52.1-0.9-0.20.20.60.50.8-0.11.3-0.4-0.5-0.51.50.4-0.60.60.4-0.80.8-0.40.70.90.90.4-0.70.3
Pavlov. Cond. response bias0.70.92.3-1.2-0.50.50.80.91.2-0.51.2-0.7-0.8-0.81.50.9-1.01.10.8-1.11.1-0.21.21.11.10.7-1.20.7
Time in closed arm before self-admin0.10.10.80.70.3-0.0-0.3-0.3-0.70.4-0.70.10.10.1-0.9-0.10.5-0.3-0.30.2-0.2-0.2-0.1-0.1-0.1-0.20.5-0.1
Time in closed arm after self-admin0.10.10.4-0.0-0.10.2-0.20.00.10.20.7-0.0-0.0-0.10.50.10.1-0.1-0.3-0.00.1-0.60.30.10.10.10.1-0.2
Time in open arm before self-admin0.40.51.3-0.9-0.40.60.50.60.7-0.40.4-0.7-0.7-0.70.90.40.40.60.5-0.91.0-0.60.71.11.10.5-0.60.8
Time in open arm after self-admin0.10.10.4-0.20.10.10.20.10.0-0.10.0-0.2-0.2-0.20.30.10.10.20.1-0.50.6-0.60.40.60.60.2-0.40.4
Bone: periosteal estimation1.43.26.81.61.6-1.1-1.7-1.8-1.82.4-0.81.21.21.4-1.2-1.92.5-2.1-2.12.2-2.0-0.6-1.9-1.8-1.9-1.62.6-2.3
Bone: periosteal perimeter0.40.73.40.40.6-0.3-0.6-0.7-0.61.2-0.30.20.30.4-0.4-0.71.8-0.9-1.11.1-0.9-0.8-0.6-0.7-0.8-0.61.5-1.2
Bone: post-yield work0.20.31.80.3-0.50.8-0.3-0.10.00.30.6-0.4-0.3-0.2-0.00.01.1-0.4-0.30.5-0.3-1.2-0.2-0.2-0.3-0.01.4-1.0
Progressive ratio test 1 active lever presses0.10.31.00.5-0.30.6-0.1-0.20.1-0.10.5-0.2-0.2-0.20.30.3-0.30.4-0.1-0.80.9-0.70.31.01.0-0.2-0.1-0.8
Progressive ratio test 1 breakpoint0.10.20.90.5-0.30.6-0.1-0.20.0-0.10.4-0.2-0.2-0.20.20.2-0.20.3-0.2-0.80.9-0.80.31.00.9-0.2-0.0-0.8
Progressive ratio test 1 inactive lever presses0.10.21.10.9-0.40.10.50.30.1-0.5-0.3-0.0-0.0-0.1-0.50.4-1.10.40.2-0.30.10.90.10.00.1-0.1-0.4-0.1
Progressive ratio test 2 active lever presses0.50.71.3-0.5-0.80.80.80.50.9-0.90.7-0.7-0.7-0.80.70.7-0.51.00.9-1.11.1-0.40.71.11.10.8-1.00.6
Progressive ratio test 2 breakpoint0.60.71.5-0.6-0.80.70.80.60.9-0.90.7-0.7-0.7-0.80.70.7-0.61.01.0-1.21.2-0.40.71.11.20.9-1.10.7
Progressive ratio test 2 inactive lever presses0.20.62.0-0.1-1.01.30.50.30.5-0.60.6-0.9-0.9-0.80.30.60.30.70.4-1.01.2-1.40.61.31.20.5-0.0-0.4
Incentive Sensitization - Responses0.20.71.6-1.1-0.70.61.00.81.0-0.90.3-0.9-0.9-0.90.50.60.20.91.2-0.70.7-0.30.50.70.71.2-0.91.3
Incentive Sensitization - Breakpoint0.40.82.0-1.1-0.80.71.10.91.1-1.00.4-0.9-1.0-1.00.60.8-0.01.01.4-0.80.7-0.20.60.70.71.2-1.11.4
Sum of active levers in priming session hrs 5-60.20.20.5-0.5-0.20.4-0.10.10.1-0.00.6-0.4-0.3-0.30.60.00.50.2-0.0-0.50.6-0.20.20.70.7-0.20.00.3
Progressive ratio2.47.011.42.33.1-3.4-2.3-2.5-2.52.6-2.63.13.13.0-2.3-2.70.4-2.6-2.43.0-3.12.8-2.7-3.2-3.1-2.61.5-1.1
Food seeking constrained by brief footshock0.10.10.40.40.3-0.3-0.3-0.2-0.50.2-0.20.40.40.30.3-0.2-0.60.1-0.4-0.40.40.30.40.40.5-0.4-0.50.5
Seeking ratio, punishment vs. effort1.53.46.9-1.5-2.02.41.51.71.6-1.71.3-2.1-2.1-2.01.51.7-0.21.81.5-2.32.5-1.92.02.62.61.6-1.21.0
Retroperitoneal fat weight0.00.11.50.6-0.40.0-0.1-0.0-0.1-0.30.30.20.20.10.00.2-1.20.40.00.1-0.30.40.1-0.4-0.4-0.0-0.2-0.4
Reaction time number correct0.41.34.51.51.2-1.4-1.0-0.9-0.70.6-2.11.41.31.3-1.8-1.1-0.7-0.9-1.00.8-0.91.5-0.8-1.0-1.0-0.9-0.00.3
Reaction time mean minus median0.42.78.3-2.1-1.72.01.51.51.5-1.22.9-1.9-1.9-1.82.41.70.81.31.5-1.31.5-1.71.41.61.51.3-0.3-0.3
Reaction time mean minus median AUC0.64.112.4-2.2-2.12.51.51.51.8-1.43.5-2.1-2.1-2.03.02.00.61.61.7-2.02.2-2.51.82.32.31.2-0.6-0.4
Reaction time num false alarms0.10.21.8-0.20.2-0.1-0.2-0.10.10.30.3-0.2-0.1-0.10.3-0.31.3-0.4-0.00.6-0.5-0.2-0.3-0.4-0.40.00.50.2
Reaction time num false alarms AUC0.20.42.8-0.10.6-0.5-0.5-0.4-0.30.7-0.10.00.10.20.1-0.71.7-0.8-0.21.0-0.80.0-0.6-0.8-0.8-0.20.80.2
Reaction time trials correct on left0.41.34.51.51.2-1.4-1.0-0.9-0.70.6-2.11.41.31.3-1.8-1.1-0.7-0.9-1.00.8-0.91.5-0.8-1.0-1.0-0.9-0.00.3
Reaction time trials on left0.41.24.11.41.1-1.4-1.1-0.9-0.70.7-2.01.31.31.3-1.7-1.1-0.6-0.9-1.00.8-0.91.5-0.8-1.0-0.9-0.90.00.3
Reaction time mean1.12.58.2-1.5-2.02.31.41.41.2-1.02.9-1.8-1.8-1.72.11.60.81.11.1-1.21.4-2.21.41.51.41.20.2-0.9
Reaction time mean AUC1.02.58.6-1.5-2.02.31.31.41.2-1.02.9-1.8-1.8-1.72.21.50.71.21.1-1.31.5-2.21.41.61.51.10.1-0.8
Median of all reaction times1.01.55.3-1.0-1.71.91.01.10.8-0.72.3-1.4-1.4-1.31.61.20.60.80.7-0.91.0-1.91.11.11.00.90.4-1.0
Reaction time omissions0.91.54.0-1.5-1.61.71.41.51.2-1.02.0-1.6-1.5-1.41.51.30.90.91.2-0.70.8-1.41.00.80.81.10.1-0.3
Reaction time false alarm rate0.30.53.7-1.0-0.10.40.10.20.20.21.2-0.8-0.7-0.61.2-0.01.9-0.20.30.4-0.1-1.0-0.10.0-0.00.30.7-0.1
Reaction time premature initiation rate0.20.31.70.90.2-0.2-0.2-0.1-0.50.4-1.30.40.40.3-1.30.0-0.2-0.1-0.70.3-0.40.20.2-0.3-0.4-0.30.4-0.1
Reaction time premature initiations0.51.56.31.81.1-1.2-1.0-0.9-1.11.0-2.51.31.31.2-2.3-0.8-0.4-0.8-1.40.9-1.01.1-0.5-1.1-1.1-0.90.5-0.0
Std. dev. reaction times0.72.38.8-1.9-1.41.91.21.21.1-0.73.0-1.8-1.7-1.62.41.21.50.91.0-1.11.3-2.31.11.51.41.00.2-0.8
Reaction time trials completed0.41.24.11.41.1-1.4-1.1-0.9-0.70.7-2.01.31.31.3-1.7-1.1-0.6-0.9-1.00.8-0.91.5-0.8-1.0-0.9-0.90.00.3
Reaction time trials AUC0.31.24.01.41.1-1.3-1.0-0.9-0.70.6-2.01.31.31.2-1.8-1.0-0.7-0.9-0.90.8-0.91.5-0.8-1.0-1.0-0.90.00.2
Run reversals in cocaine runway, females0.20.21.80.5-0.1-0.0-0.1-0.00.5-0.20.20.30.20.10.30.4-1.30.1-0.1-0.50.40.50.60.40.4-0.2-0.6-0.1
Run reversals in cocaine runway, males0.60.72.0-0.7-0.91.00.80.80.7-0.60.7-1.1-1.1-1.00.40.80.50.71.0-0.60.7-0.80.90.80.71.4-0.20.5
Latency to leave start box in cocaine runway0.40.61.8-0.7-1.21.30.90.80.3-0.60.2-1.1-1.1-1.00.20.80.60.50.6-0.50.6-1.20.80.60.60.40.2-0.1
Latency to leave start box in cocaine runway, F0.40.61.7-0.7-1.21.30.60.50.2-0.80.5-1.0-1.0-0.90.50.80.30.50.7-0.70.8-1.00.60.80.80.20.0-0.1
Latency to leave start box in cocaine runway, M0.10.10.3-0.1-0.30.30.50.30.00.1-0.4-0.2-0.2-0.3-0.30.10.40.0-0.00.3-0.3-0.40.5-0.3-0.30.20.40.0
Std. dev. time between licks in bursts0.50.97.6-0.6-0.61.20.50.40.30.20.4-1.2-1.2-1.00.00.22.8-0.1-0.20.4-0.1-2.10.50.1-0.00.71.3-0.6
Total sessions with >9 infusions0.30.41.80.30.4-0.1-0.7-0.6-0.30.31.30.30.30.31.2-0.5-0.0-0.2-0.5-0.70.7-0.1-0.40.80.9-0.5-0.2-0.9
Short access day 1 total inactive lever presses0.20.41.30.1-0.51.0-0.3-0.40.0-0.00.6-0.5-0.5-0.30.5-0.00.60.0-0.5-0.71.0-0.8-0.11.11.1-0.20.4-0.9
Short access day 10 total inactive lever presses0.10.62.0-0.1-0.80.41.11.10.5-0.9-1.1-0.8-0.7-0.6-1.00.70.50.41.10.4-0.51.1-0.3-0.6-0.60.8-0.01.4
Short access day 1 total infusions0.30.51.9-0.1-0.30.7-0.3-0.20.0-0.11.2-0.3-0.3-0.21.10.00.20.3-0.1-1.11.2-0.9-0.11.41.4-0.1-0.1-1.1
Short access day 10 total infusions0.30.52.1-0.1-0.40.50.10.20.3-0.61.5-0.3-0.3-0.21.30.3-0.60.70.4-1.11.10.30.21.11.20.0-0.8-0.1
Short access total infusions0.50.73.4-0.1-0.30.6-0.3-0.20.2-0.31.8-0.2-0.2-0.21.70.1-0.30.4-0.1-1.21.3-0.50.01.41.4-0.2-0.5-1.0
Short access day 1 locomotion0.40.72.1-0.7-1.01.10.70.90.8-1.01.4-1.0-0.9-0.81.20.70.40.91.1-0.80.8-0.10.20.80.80.8-0.40.2
Short access day 10 total locomotion0.93.86.01.71.9-1.5-1.9-1.9-2.22.1-1.81.41.51.7-2.3-2.22.0-2.4-1.82.3-2.10.3-2.3-2.0-2.1-1.72.4-1.7
Short access total locomotion0.40.62.40.90.5-0.1-1.0-0.9-1.00.70.20.40.40.6-0.3-0.91.0-0.9-0.90.6-0.5-0.3-1.0-0.4-0.4-0.81.2-1.5
One hour access (0.3 mA shock)1.82.14.7-1.6-1.61.41.61.61.7-1.81.0-1.5-1.6-1.60.71.7-0.21.62.1-1.31.2-0.41.21.11.12.2-1.41.8
Compulsive drug intake0.91.43.5-1.1-1.61.41.31.61.2-1.2-0.0-1.7-1.6-1.5-0.51.41.20.71.80.4-0.4-0.30.7-0.5-0.61.90.51.1
One hour access (shock baseline)0.20.62.0-0.4-0.10.10.1-0.10.5-0.51.20.1-0.1-0.21.20.3-1.30.70.2-1.41.3-0.30.51.31.40.3-1.40.4
Social response proportion1.01.33.61.10.9-0.6-1.1-1.0-1.11.3-0.40.80.80.9-0.6-1.11.6-1.4-1.51.2-1.0-0.6-1.3-0.9-1.0-0.91.6-1.9
Social responses1.01.33.10.71.2-1.0-1.0-0.8-1.11.3-0.90.91.01.0-1.0-1.21.8-1.3-1.21.4-1.30.1-1.5-1.3-1.3-1.01.3-1.1
Social time0.50.85.2-1.0-0.90.90.81.00.5-0.60.1-1.3-1.2-1.0-0.10.52.3-0.30.80.7-0.6-0.9-0.0-0.6-0.71.30.90.4
Soleus weight0.92.616.80.90.10.8-1.3-1.3-1.01.5-0.4-0.2-0.10.2-1.2-0.84.1-1.9-1.21.7-1.3-2.8-1.4-0.9-1.1-0.83.3-2.4
Bone: stiffness0.50.91.71.30.7-1.0-0.9-0.7-1.00.5-0.91.11.11.0-1.1-0.9-0.6-0.8-0.91.1-1.21.3-0.9-1.3-1.3-0.80.5-0.2
Tibialis anterior weight0.10.31.20.20.4-0.7-0.3-0.20.1-0.1-0.60.50.50.4-0.4-0.2-1.0-0.0-0.20.3-0.51.1-0.4-0.7-0.60.1-0.50.6
Time to tail flick, vehicle, before self-admin0.50.62.4-1.1-0.60.01.21.10.9-0.90.6-0.5-0.4-0.40.10.6-0.50.41.20.5-0.71.60.4-0.9-0.90.8-0.41.1
Time to tail flick, vehicle, after self-admin0.10.31.0-0.8-0.40.60.60.50.3-0.21.0-0.6-0.5-0.50.90.20.30.20.3-0.40.5-0.70.20.60.60.30.0-0.4
Time to tail flick, test, before self-admin0.30.43.1-0.90.3-0.50.70.60.6-0.3-0.5-0.1-0.1-0.2-0.60.4-0.20.50.40.1-0.21.00.3-0.3-0.30.5-0.81.8
Time to tail flick, test, after self-admin2.82.95.8-2.1-1.41.32.02.02.0-1.70.7-1.6-1.6-1.71.11.8-0.52.01.8-1.81.7-0.62.01.71.71.9-1.92.4
Delta time to tail flick, vehicle, before/after SA1.21.34.2-0.6-0.81.10.40.50.5-0.61.3-0.7-0.7-0.81.60.7-0.81.10.3-1.92.0-1.41.02.12.10.4-1.00.1
Delta time to tail flick, test, before/after SA0.91.21.9-0.9-1.41.21.21.31.3-1.21.0-0.9-1.0-1.01.21.3-0.81.21.2-1.11.1-0.51.31.01.00.9-1.00.7
Tibia length1.74.711.92.11.7-1.3-2.1-1.9-2.42.4-1.51.41.51.6-2.3-2.23.4-2.6-1.72.8-2.6-0.1-2.5-2.4-2.5-1.43.0-2.1
Ambulatory time before self-admin0.00.10.4-0.4-0.60.40.40.30.4-0.50.6-0.3-0.3-0.30.40.4-0.00.30.60.0-0.10.20.1-0.1-0.20.5-0.00.3
Ambulatory time after self-admin1.01.62.51.21.4-1.3-1.1-1.3-1.21.3-0.91.11.21.3-0.9-1.51.2-1.6-1.11.6-1.51.0-1.5-1.5-1.5-0.91.2-0.8
Bone: tissue strength0.20.20.50.70.1-0.0-0.6-0.6-0.60.40.70.40.40.40.3-0.2-0.3-0.4-0.50.0-0.0-0.2-0.20.00.0-0.70.4-0.7
Total heroin consumption0.10.10.6-0.40.0-0.10.20.40.3-0.1-0.6-0.2-0.1-0.1-0.40.10.8-0.10.10.4-0.40.4-0.3-0.4-0.40.10.20.7
Bone: trabecular number2.54.78.5-2.0-2.31.82.82.62.2-2.92.3-1.8-1.8-1.92.12.3-2.12.42.4-2.32.10.52.01.81.92.3-2.61.9
Bone: trabecular spacing3.24.79.02.22.4-2.0-2.7-2.7-2.33.0-1.12.12.12.2-1.0-2.41.6-2.4-2.42.3-2.10.0-2.1-1.8-1.9-2.72.6-1.9
Bone: trabecular thickness1.92.64.6-1.3-1.91.32.12.11.6-2.11.3-1.3-1.3-1.51.01.9-1.81.91.7-1.61.40.21.91.21.22.0-2.00.9
Bone: trabecular tissue density0.20.31.60.20.8-0.4-0.8-0.5-0.50.7-1.30.20.20.3-0.7-0.70.6-0.5-0.5-0.00.2-0.6-0.30.30.3-0.40.1-0.0
Water consumed over 24 hours0.00.10.4-0.1-0.00.2-0.1-0.1-0.20.2-0.4-0.1-0.1-0.0-0.4-0.20.6-0.20.00.3-0.3-0.3-0.3-0.2-0.20.10.6-0.3
Number of responses in last shaping day0.91.14.60.80.9-0.1-1.3-1.3-1.01.6-0.30.40.40.5-0.3-1.02.1-1.4-1.30.7-0.3-1.8-0.4-0.0-0.1-1.01.7-1.6