Hub : Genes

Rab33b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Rab33b 0.06 0.03 4.3e-06 0.03 0.04 0.03 0.03 3.3e-04 4.4e-05 5.3e-04 2.7e-04
2 Adipose mRNA stability Rab33b 0.02 0.02 9.2e-03 0.01 0 0 0 6.6e-02 1.1e-01 2.1e-01 1.7e-01
3 Brain gene expression Rab33b 0.08 0.04 2.3e-10 0.1 0.11 0.11 0.12 9.9e-10 1.6e-10 9.7e-11 8.0e-11
4 PL isoform ratio NM_001108944.1 0.03 0.02 9.7e-03 0.02 0.01 0.01 0.01 1.6e-03 2.8e-02 7.0e-02 1.8e-02
5 PL isoform ratio XM_063282252.1 0.03 0.02 9.2e-03 0.02 0.01 0.01 0.01 1.3e-03 2.2e-02 5.2e-02 1.4e-02
6 pVTA gene expression Rab33b 0.08 0.04 6.9e-08 0.04 0.05 0.04 0.04 2.1e-04 4.5e-05 3.5e-04 3.1e-04
7 PL gene expression Rab33b 0.08 0.04 7.4e-10 0.09 0.07 0.08 0.08 2.9e-10 2.6e-08 5.3e-09 4.1e-09
8 NAcc gene expression Rab33b 0.12 0.05 0.0e+00 0.15 0.15 0.15 0.15 1.6e-22 7.3e-22 8.2e-22 1.3e-21
9 IC gene expression Rab33b 0.12 0.07 4.6e-05 0.07 0.07 0.05 0.06 6.0e-04 8.9e-04 2.8e-03 1.3e-03
10 Adipose gene expression Rab33b 0.05 0.03 2.6e-05 0.01 0.02 0.02 0.01 2.5e-02 1.8e-03 6.5e-03 7.6e-03
11 BLA gene expression Rab33b 0.1 0.06 1.1e-05 0.1 0.09 0.06 0.09 3.5e-06 3.0e-05 4.4e-04 1.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.32.27.0-2.6-0.6-1.20.6-0.6-1.6-1.6-1.5-1.6-1.6-1.5
Area under the delay curve0.20.30.70.00.4-0.7-0.20.2-0.4-0.7-0.7-0.7-0.9-0.3
BMI with tail0.93.14.61.62.11.9-1.91.91.81.61.71.81.41.3
BMI without tail0.00.10.3-0.20.2-0.10.1-0.1-0.1-0.4-0.30.1-0.5-0.0
Body weight0.52.34.31.82.11.6-1.71.71.51.51.60.81.10.8
Weight adjusted by age0.10.20.80.10.30.4-0.30.30.50.40.40.20.50.9
Bone surface0.51.02.00.31.40.9-1.41.40.90.80.90.90.50.7
Bone volume0.10.20.6-0.50.80.4-0.80.80.30.30.30.30.10.0
Breakpoint value in progressive ratio session0.20.20.5-0.50.1-0.5-0.10.1-0.2-0.7-0.7-0.5-0.70.3
Number of licking bursts0.10.20.30.40.50.3-0.50.50.30.60.50.20.5-0.1
Context. condit. distance diff. score2.32.84.2-2.1-1.9-1.31.8-1.8-1.7-1.5-1.4-2.0-1.1-1.6
Locomotion velocity, session 14.54.96.31.82.32.3-2.22.22.42.12.22.01.92.5
Locomotion distance, session 13.34.15.02.22.01.9-2.02.02.12.02.12.11.82.2
Locomotion velocity, session 26.67.710.02.72.42.7-2.32.33.23.13.12.83.02.9
Locomotion distance, session 24.15.78.52.91.42.6-1.51.52.62.92.92.32.91.8
Locomotion velocity, session 30.50.62.5-0.0-1.60.31.3-1.3-0.10.10.10.20.6-0.2
Locomotion distance, session 30.40.41.60.0-1.30.11.0-1.0-0.4-0.1-0.1-0.10.2-0.6
Stereotopy head waving bouts, day 30.81.02.41.00.50.8-0.40.41.11.11.11.51.11.1
Stereotopy head waving duration, day 31.31.63.51.10.81.1-0.70.71.41.31.31.91.31.7
Locomotion velocity, session 70.50.61.1-0.8-0.8-0.70.6-0.6-0.8-0.7-0.8-1.0-0.7-0.8
Locomotion distance, session 71.92.45.2-1.8-1.5-1.41.3-1.3-1.6-1.2-1.3-1.9-1.1-2.3
Stereotopy head waving bouts, day 70.70.81.80.90.30.8-0.20.21.00.90.91.31.11.2
Stereotopy head waving duration, day 70.50.61.70.70.10.80.0-0.00.90.80.81.21.01.3
Locomotion velocity, session 81.41.62.61.60.91.2-1.11.11.51.31.31.31.11.5
Locomotion distance, session 80.60.92.61.0-0.31.20.0-0.00.91.31.40.41.60.6
Degree of sensitization distance1.51.63.3-1.7-0.5-1.20.4-0.4-1.3-1.1-1.1-1.7-1.3-1.8
Degree of sensitization stereotypy0.10.10.60.20.20.2-0.00.00.30.20.20.60.40.8
Conditioned locomotion0.50.51.4-0.4-1.1-0.41.2-1.2-0.7-0.6-0.6-0.4-0.1-0.4
Cocaine response after cond. corrected0.20.20.3-0.3-0.4-0.60.5-0.5-0.5-0.5-0.4-0.1-0.3-0.5
Cocaine response after cond. not corrected0.10.20.4-0.2-0.3-0.70.4-0.4-0.4-0.5-0.40.1-0.4-0.1
Cocaine response before conditioning0.30.40.90.10.80.2-0.90.90.60.20.20.7-0.20.9
Saline control response0.60.82.81.70.41.1-0.30.30.80.90.80.40.91.0
Bone: connectivity density0.81.23.6-1.90.2-1.1-0.30.3-1.0-1.3-1.2-1.2-1.6-0.7
Bone: cortical apparent density0.50.72.5-1.6-1.0-0.20.9-0.9-0.7-0.5-0.5-0.80.0-0.8
Bone: cortical area2.03.04.21.31.91.9-1.91.91.81.51.62.11.21.8
Bone: cortical porosity0.40.40.90.90.50.3-0.60.60.80.50.50.70.30.9
Bone: cortical porosity0.80.81.41.01.00.5-1.11.11.00.70.71.00.41.2
Bone: cortical thickness0.20.30.90.10.60.5-0.70.70.60.10.20.70.00.9
Bone: cortical thickness0.00.00.1-0.00.2-0.0-0.10.10.20.10.00.20.10.3
Bone: cortical tissue density0.50.62.3-1.5-1.0-0.20.9-0.9-0.7-0.5-0.4-0.80.1-0.8
Condit. Reinf. active minus inactive responses0.10.10.50.7-0.20.20.2-0.2-0.00.30.3-0.30.2-0.7
Condit. Reinf. active-inactive response ratio0.80.82.0-0.2-1.1-0.71.0-1.0-1.0-0.7-0.7-1.1-0.7-1.4
Condit. Reinf. active responses1.21.44.62.10.81.2-0.70.71.21.41.40.81.20.6
Condit. Reinf. inactive responses4.15.08.22.91.92.2-1.81.82.52.42.42.12.22.3
Incentive salience index mean2.22.65.42.31.21.8-1.21.21.71.91.91.41.71.1
Condit. Reinf. lever presses6.89.612.53.52.63.1-2.52.53.43.53.43.33.13.0
Condit. Reinf. active minus inactive responses0.10.10.30.3-0.30.10.2-0.2-0.4-0.4-0.4-0.3-0.4-0.5
Condit. Reinf. active-inactive response ratio1.92.24.3-0.5-2.1-0.82.0-2.0-1.5-1.2-1.2-1.5-1.0-1.7
Condit. Reinf. active responses1.82.53.01.71.61.7-1.71.71.51.41.41.71.11.5
Condit. Reinf. inactive responses6.48.211.52.43.42.4-3.43.42.92.52.53.02.03.2
Condit. Reinf. lever presses1.01.43.71.9-0.01.8-0.10.11.01.41.31.21.50.3
Condit. Reinf. lever reinforcers received1.82.53.11.71.61.8-1.71.71.51.41.41.81.11.5
Conditioned reinforcement - actives0.50.92.7-0.61.6-0.4-1.61.60.1-0.7-0.7-0.3-0.9-0.2
Conditioned reinforcement - inactives1.42.03.70.91.91.0-1.91.91.50.80.91.40.91.8
Conditioned locomotion1.82.32.91.31.61.6-1.71.71.71.41.41.51.31.4
Patch foraging indifference point 0 sec0.81.53.10.90.81.8-0.70.71.21.61.61.01.70.7
Patch foraging indifference point AUC0.10.10.50.7-0.20.30.2-0.20.20.10.20.40.10.7
Delay disc. indifference point, 0s delay0.80.91.6-1.30.8-0.9-0.80.8-0.6-1.0-1.0-1.0-1.1-0.8
Delay disc. indifference point, 16s delay0.20.20.50.70.1-0.3-0.40.40.1-0.3-0.4-0.4-0.50.6
Delay disc. indifference point, 2s delay0.10.20.40.10.5-0.2-0.70.7-0.1-0.2-0.2-0.2-0.4-0.5
Delay disc. indifference point, 24s delay3.33.74.7-1.5-1.5-2.11.8-1.8-2.1-2.0-2.0-2.0-2.0-2.2
Delay disc. indifference point, 4s delay0.30.31.40.21.20.0-0.90.90.3-0.00.1-0.1-0.10.5
Delay disc. indifference point, 8s delay1.21.42.6-0.7-0.3-1.40.5-0.5-1.3-1.4-1.5-1.4-1.6-1.3
Indifference point function ln k0.10.10.4-0.50.30.2-0.20.2-0.10.10.0-0.30.1-0.7
Indifference point function log k0.10.10.4-0.50.30.2-0.20.2-0.10.10.0-0.30.1-0.7
Patch foraging total patch changes 0 sec0.61.12.10.60.91.5-0.80.81.01.31.30.91.40.6
Patch foraging total patch changes 12 sec0.20.30.60.50.40.8-0.30.30.60.60.60.50.70.7
Patch foraging total patch changes 18 sec0.81.22.21.50.61.2-0.60.61.11.11.21.21.11.2
Patch foraging total patch changes 24 sec0.71.12.31.50.41.5-0.40.41.01.31.41.01.30.7
Patch foraging total patch changes 6 sec2.94.46.81.91.52.4-1.51.52.32.22.32.32.32.6
Patch foraging time to switch 0 sec0.20.30.7-0.2-0.8-0.90.8-0.8-0.5-0.4-0.4-0.3-0.4-0.6
Patch foraging water rate 0 sec0.10.20.6-0.50.80.7-0.70.70.20.20.10.00.0-0.0
Patch foraging water rate 12 sec0.30.61.8-0.21.30.7-1.11.10.60.40.30.40.20.8
Patch foraging water rate 18 sec0.10.20.7-0.10.50.8-0.60.60.30.30.30.10.30.1
Patch foraging water rate 24 sec0.30.41.3-0.10.61.2-0.50.50.60.60.70.10.70.6
Patch foraging water rate 6 sec0.10.20.5-0.40.70.3-0.60.6-0.00.1-0.1-0.7-0.2-0.3
Seeking ratio, delayed vs. immediate footshock0.60.71.7-0.70.2-1.0-0.20.2-0.8-1.0-1.1-1.3-1.2-0.6
Distance traveled before self-admin0.40.61.70.3-1.2-0.21.3-1.3-0.6-0.3-0.3-0.7-0.2-0.7
Distance traveled after self-admin1.31.63.11.7-0.71.40.7-0.71.01.41.41.31.61.4
Extensor digitorum longus weight2.49.618.04.21.53.9-1.41.43.33.33.43.33.53.2
Bone: elastic displacement3.74.210.2-0.7-3.2-1.43.1-3.1-1.8-1.7-1.6-1.7-1.0-1.5
Bone: elastic work0.40.51.01.0-0.80.80.8-0.80.40.60.50.80.90.3
Bone: endosteal estimation2.55.56.72.42.52.3-2.32.32.42.42.52.62.01.9
Bone: endosteal perimeter0.71.42.91.01.70.9-1.41.41.11.01.01.30.71.0
Epididymis fat weight0.10.20.90.90.60.3-0.50.50.20.10.1-0.2-0.10.3
Delta time in closed arm before/after self-admin1.61.53.6-1.40.1-1.50.0-0.0-1.2-1.4-1.4-1.9-1.4-1.3
Delta time in open arm before/after self-admin0.90.93.00.5-1.70.31.7-1.7-0.30.30.30.20.5-0.4
Diff in mean of infusions in LGA sessions0.20.20.50.7-0.60.30.6-0.60.20.30.30.50.30.6
Delay discount exponential model param0.40.40.90.1-0.20.8-0.00.00.60.80.90.81.00.5
Extinction: sum of active levers before priming1.31.52.0-0.5-1.2-1.31.3-1.3-1.3-1.1-1.1-1.2-1.3-1.4
Active lever presses in extinction session 60.20.20.5-0.10.0-0.6-0.10.1-0.2-0.6-0.6-0.4-0.7-0.0
Bone: final force2.13.34.21.51.82.1-1.81.82.01.81.81.91.61.9
Bone: final moment2.64.25.81.81.82.4-1.91.92.32.12.12.21.92.1
Food consumed during 24 hour testing period0.20.30.80.3-0.30.70.3-0.30.10.70.7-0.40.9-0.5
Glucose0.61.01.4-1.0-0.9-1.11.0-1.0-1.1-0.9-0.9-1.0-0.7-1.2
Heart weight0.71.12.4-1.30.7-0.9-0.70.7-0.7-0.8-0.9-1.6-1.2-1.4
Delay discount hyperbolic model param0.40.51.00.2-0.30.80.1-0.10.60.80.90.91.00.7
Intermittent access intake day 1-15 change0.30.61.91.4-0.90.80.8-0.80.20.70.70.60.6-0.5
Intermittent access intake escalation0.30.52.31.5-0.80.70.7-0.70.20.60.60.50.5-0.3
Intermittent access intake escalation 21.01.23.31.6-1.80.61.7-1.7-0.10.50.60.40.6-0.0
Intermitt. access day 1 inactive lever presses0.72.75.21.12.01.1-2.32.31.61.00.91.71.02.2
Intermitt. access day 15 inactive lever presses0.20.40.8-0.4-0.6-0.80.6-0.6-0.5-0.7-0.9-0.9-0.80.3
Intermitt. access escalation Index1.92.73.8-1.6-1.0-1.81.1-1.1-1.8-1.9-1.9-1.7-2.0-1.8
Intermittent access day 1 total infusions0.91.53.70.71.80.7-1.91.91.20.60.50.80.31.2
Intermittent access day 15 total infusions0.20.30.80.90.80.4-0.90.90.40.20.20.2-0.0-0.2
Intermittent access terminal intake (last 3 days)0.71.02.41.60.61.1-0.80.81.11.01.01.10.70.6
Intermittent access total infusions0.60.71.80.71.40.5-1.41.40.80.30.40.40.10.4
Intermittent access day 1 locomotion1.31.73.70.61.70.9-1.91.91.30.70.71.40.61.4
Intermittent access day 15 total locomotion1.22.22.81.51.41.6-1.51.51.71.31.41.71.31.4
Intermittent access total locomotion2.32.83.61.51.61.8-1.71.71.91.61.71.81.51.6
Intermittent access standard deviation0.00.10.40.6-0.40.20.3-0.30.10.10.1-0.1-0.0-0.1
Left kidney weight0.10.30.50.7-0.10.50.4-0.40.40.70.5-0.30.70.4
Right kidney weight0.10.41.20.6-0.90.31.1-1.1-0.00.50.4-0.20.70.0
Cocaine induced anxiety0.10.20.30.3-0.6-0.40.6-0.6-0.4-0.1-0.30.0-0.4-0.4
Post-drug Anxiety0.40.40.80.2-0.90.50.9-0.90.20.70.60.90.70.4
Baseline Anxiety1.01.12.6-0.1-0.11.20.1-0.11.01.11.31.31.61.6
Tail length0.10.30.8-0.0-0.1-0.70.6-0.6-0.4-0.7-0.7-0.7-0.90.0
Length with tail0.20.82.81.70.90.9-0.60.61.00.90.9-0.00.61.0
Length without tail1.44.67.82.82.12.2-2.12.12.22.42.31.22.11.7
Times rat made contact with spout0.30.40.90.0-0.80.70.8-0.8-0.20.50.5-0.30.7-1.0
Lifetime Intake0.81.03.20.61.80.3-1.81.80.90.10.20.2-0.10.5
Liver weight, left1.01.62.21.51.21.3-1.11.11.31.21.21.51.11.4
Liver weight, right1.73.05.31.41.12.0-1.01.02.01.91.92.32.02.0
Locomotor activity3.04.78.93.02.02.0-2.02.02.22.01.92.41.72.4
Locomotor testing distance1.42.66.12.51.61.5-1.61.61.61.31.21.51.01.9
Locomotor testing rearing0.61.22.31.51.20.7-1.21.21.20.90.70.90.71.5
Locomotion in novel chamber0.30.40.80.2-0.50.90.6-0.60.30.80.60.90.8-0.0
Locomotion in novel chamber post-restriction0.40.62.0-0.31.3-0.1-1.41.40.4-0.1-0.30.4-0.40.5
Fecal boli incidents, locomotor time 10.10.20.50.4-0.2-0.40.6-0.6-0.4-0.3-0.4-0.3-0.4-0.7
Change in fecal boli incidents, locomotor task0.10.10.3-0.20.20.4-0.40.40.30.30.30.50.40.2
Time >=10cm from walls, locomotor time 10.00.00.1-0.20.20.20.0-0.00.10.20.20.40.30.1
Bouts of movement, locomotor time 11.01.12.8-0.91.7-0.6-1.51.5-0.1-0.8-0.9-0.8-1.00.2
Total resting periods, locomotor time 11.11.23.4-1.01.8-0.7-1.71.7-0.1-0.8-0.9-0.8-1.10.2
Rest time, locomotor task time 10.81.02.9-1.11.7-0.5-1.51.5-0.1-0.7-0.8-0.8-0.8-0.3
Distance moved, locomotor task time 11.42.06.4-0.3-2.5-0.92.4-2.4-1.2-0.7-0.5-0.8-0.5-0.8
Vertical activity count, locomotor time 10.92.27.60.3-2.6-0.12.8-2.8-0.80.20.3-0.10.5-0.9
Time >=10cm from walls, locomotor time 20.10.10.3-0.30.5-0.2-0.30.3-0.1-0.2-0.1-0.6-0.3-0.4
Bouts of movement, locomotor time 21.52.44.2-2.01.5-1.6-1.31.3-0.9-1.8-2.0-1.3-2.1-0.5
Total resting periods, locomotor time 21.11.93.0-1.61.7-1.3-1.51.5-0.5-1.5-1.7-1.0-1.7-0.1
Rest time, locomotor task time 20.70.92.00.51.40.8-1.31.31.00.70.50.70.60.9
Distance moved, locomotor task time 21.51.83.4-0.9-1.8-1.31.7-1.7-1.4-1.2-1.1-1.3-1.1-0.9
Vertical activity count, locomotor time 20.60.82.90.1-1.7-0.21.7-1.7-0.50.00.1-0.10.2-0.4
Light reinforcement 10.20.40.70.80.80.6-0.60.60.60.40.40.40.40.8
Light reinforcement 23.85.97.62.42.82.4-2.62.62.62.22.31.62.12.7
Bone: marrow area2.75.87.12.42.62.4-2.32.32.52.52.52.72.11.9
Bone: maximum diameter3.36.17.92.02.52.8-2.32.32.62.52.52.82.32.4
Bone: maximum force1.32.33.01.41.51.7-1.41.41.61.61.71.71.51.3
Bone: maximum moment1.83.14.21.71.52.0-1.41.41.91.91.92.01.81.5
Mean time between licks in bursts0.51.12.51.60.71.0-0.70.71.11.21.21.01.20.9
Mean num. licks in bursts0.50.71.7-0.7-1.3-0.31.3-1.3-0.7-0.6-0.6-0.7-0.4-0.7
Cd content in liver0.20.30.70.00.7-0.1-0.80.80.2-0.2-0.1-0.2-0.20.8
Co content in liver0.20.20.5-0.1-0.2-0.60.4-0.4-0.4-0.7-0.6-0.6-0.70.0
Cu content in liver0.20.20.50.70.60.2-0.20.20.40.30.40.40.40.7
Fe content in liver2.02.43.3-1.2-1.4-1.71.6-1.6-1.7-1.8-1.8-1.3-1.6-1.1
K content in liver3.53.45.11.62.31.7-2.12.12.01.71.91.41.41.7
Mg content in liver2.32.44.21.42.11.3-1.81.81.61.41.61.01.11.4
Mn content in liver0.40.51.2-1.00.1-1.0-0.00.0-0.6-0.8-0.8-0.5-1.1-0.6
Na content in liver2.32.53.11.41.81.3-1.81.81.71.51.81.21.51.4
Rb content in liver0.20.20.80.90.1-0.20.2-0.20.4-0.00.30.60.30.6
Se content in liver0.10.10.4-0.60.1-0.30.0-0.0-0.3-0.5-0.4-0.2-0.6-0.4
Sr content in liver2.42.13.6-1.6-1.3-1.50.9-0.9-1.5-1.7-1.7-1.1-1.9-1.6
Zn content in liver0.40.41.5-0.51.20.1-1.01.0-0.10.10.1-0.4-0.2-0.5
Bone: minimum diameter1.63.06.11.42.51.4-2.22.21.71.31.31.80.71.7
Time in familiar zone, hab. session 11.81.83.91.50.01.6-0.30.31.41.41.42.01.61.5
Time in novel zone, hab. session 12.42.44.4-1.9-0.2-1.80.4-0.4-1.6-1.7-1.6-2.1-1.9-1.7
Total zone transitions, hab. session 12.53.54.42.11.72.1-1.91.92.01.91.91.51.61.8
Total locomotion distance, hab. session 10.10.20.40.30.50.5-0.60.60.50.40.40.40.40.3
Locomotion velocity, hab. session 10.00.10.10.30.20.3-0.30.30.30.20.20.30.20.2
Time in familiar zone, hab. session 20.10.10.50.0-0.10.70.3-0.30.30.10.20.40.30.5
Time in novel zone, hab. session 21.51.52.6-1.0-1.0-1.60.9-0.9-1.4-1.2-1.2-1.5-1.1-1.6
Total zone transitions, hab. session 25.67.210.72.52.43.3-2.42.42.92.82.82.52.62.8
Total locomotion distance, hab. session 20.91.22.70.91.01.6-1.11.11.11.21.10.81.10.9
Locomotion velocity, hab. session 21.52.13.61.11.51.9-1.51.51.41.51.41.21.31.3
Novel to familiar place preference ratio0.10.10.3-0.60.20.3-0.30.3-0.00.00.1-0.10.1-0.1
Novelty place preference0.00.00.4-0.60.20.2-0.10.1-0.10.00.1-0.10.1-0.2
Time in novel zone, NPP test0.10.10.5-0.7-0.10.10.1-0.1-0.2-0.1-0.1-0.20.1-0.3
Total zone transitions, NPP test2.33.34.51.91.81.8-1.91.91.91.61.71.81.42.1
Total locomotion distance, NPP test1.31.83.10.91.71.2-1.81.81.31.11.11.10.91.3
Locomotion velocity, NPP test1.42.03.21.11.71.3-1.81.81.41.21.21.20.91.5
Intraocular pressure0.71.02.0-1.0-0.3-1.10.2-0.2-1.1-1.1-1.0-1.4-1.3-1.4
Delta distance traveled before/after self-admin2.32.44.81.60.31.6-0.40.41.61.71.72.11.92.2
Delta ambulatory time before/after self-admin1.21.43.01.30.11.2-0.10.11.21.31.31.61.51.7
Parametrial fat weight0.92.17.32.70.81.5-0.70.71.51.51.41.41.31.6
Pavlov. Cond. lever latency7.18.911.6-3.2-2.3-3.12.3-2.3-3.3-3.4-3.3-3.2-3.2-2.8
Pavlov. Cond. magazine entry latency0.10.10.30.20.30.5-0.30.30.30.50.30.10.4-0.2
Pavlov. Cond. change in total contacts2.02.22.61.31.61.6-1.61.61.51.61.51.31.31.1
Pavlov. Cond. index score2.53.24.81.71.42.1-1.41.41.92.22.11.72.11.3
Pavlov. Cond. latency score3.44.36.02.01.82.3-1.81.82.32.42.32.02.31.7
Pavlov. Cond. lever contacts6.07.19.52.82.22.8-2.32.32.93.13.02.72.82.3
Pavlov. Cond. magazine entry number0.30.30.9-0.1-0.5-0.80.3-0.3-0.4-0.9-0.7-0.0-1.00.4
Pavlov. Cond. intertrial magazine entries1.01.21.8-0.7-1.1-1.31.1-1.1-1.2-1.1-1.0-1.3-0.9-1.1
Pavlov. Cond. lever-magazine prob. diff.2.43.04.31.71.42.0-1.41.41.92.11.91.72.01.4
Pavlov. Cond. response bias1.92.44.11.51.21.9-1.11.11.62.01.81.41.90.9
Pavlov. Cond. lever latency3.44.66.9-2.6-1.7-2.61.8-1.8-2.2-2.4-2.4-2.1-2.1-1.6
Pavlov. Cond. magazine entry latency2.83.36.12.40.62.4-0.70.71.82.22.21.72.51.4
Pavlov. Cond. change in total contacts2.84.56.82.62.02.4-2.12.12.12.22.21.81.81.6
Pavlov. Cond. index score3.64.88.32.91.42.7-1.51.52.22.52.52.02.51.6
Pavlov. Cond. latency score3.54.77.92.81.52.7-1.61.62.22.52.52.02.41.6
Pavlov. Cond. lever contacts3.95.48.62.71.72.9-1.91.92.42.72.62.32.41.8
Pavlov. Cond. magazine entry number3.34.07.6-2.8-0.7-2.70.9-0.9-2.0-2.4-2.4-1.7-2.6-1.4
Pavlov. Cond. intertrial magazine entries0.60.91.9-1.0-0.8-1.40.9-0.9-0.9-1.2-1.2-0.7-1.1-0.5
Pavlov. Cond. lever-magazine prob. diff.2.93.96.72.61.22.5-1.31.32.02.32.21.82.31.5
Pavlov. Cond. response bias4.96.710.03.11.93.2-2.12.12.72.92.82.52.72.2
Time in closed arm before self-admin0.60.81.50.50.51.0-0.60.61.01.01.01.21.10.9
Time in closed arm after self-admin0.30.30.7-0.40.8-0.4-0.80.8-0.2-0.4-0.4-0.6-0.6-0.4
Time in open arm before self-admin0.70.81.60.91.30.7-1.21.20.80.60.60.50.50.9
Time in open arm after self-admin0.70.82.6-0.3-1.4-0.11.6-1.6-0.7-0.2-0.2-0.3-0.0-0.8
Bone: periosteal estimation3.16.69.12.42.82.6-2.62.62.72.52.53.02.12.3
Bone: periosteal perimeter1.52.54.71.12.21.3-1.91.91.71.21.11.70.82.0
Bone: post-yield work0.10.20.40.60.40.2-0.10.10.30.50.50.50.3-0.3
Progressive ratio test 1 active lever presses0.81.03.00.31.70.4-1.71.70.90.30.30.60.10.6
Progressive ratio test 1 breakpoint1.01.23.10.51.80.6-1.81.81.10.50.50.80.30.8
Progressive ratio test 1 inactive lever presses0.81.22.01.01.40.8-1.41.41.20.80.71.10.61.2
Progressive ratio test 2 active lever presses1.01.23.60.61.80.5-1.91.91.00.50.50.60.20.2
Progressive ratio test 2 breakpoint1.01.23.50.71.80.5-1.91.91.00.50.50.60.30.2
Progressive ratio test 2 inactive lever presses1.11.85.41.02.30.3-2.32.31.10.30.30.60.11.1
Incentive Sensitization - Responses0.81.21.91.21.40.8-1.41.41.10.90.91.00.80.6
Incentive Sensitization - Breakpoint0.60.81.41.11.10.7-1.21.20.90.80.80.80.60.4
Sum of active levers in priming session hrs 5-60.20.20.80.8-0.00.10.3-0.30.40.20.20.60.20.9
Progressive ratio1.62.45.0-1.80.2-1.9-0.30.3-1.4-2.0-2.0-1.9-2.2-1.2
Food seeking constrained by brief footshock0.91.12.4-0.70.6-0.9-0.60.6-0.9-1.1-1.1-1.3-1.4-1.6
Seeking ratio, punishment vs. effort0.20.30.70.7-0.20.80.2-0.20.40.80.70.50.9-0.1
Retroperitoneal fat weight0.10.64.12.00.40.6-0.40.40.60.60.50.00.30.7
Reaction time number correct0.00.00.1-0.20.10.3-0.30.30.20.20.1-0.20.20.2
Reaction time mean minus median0.61.54.21.8-1.90.42.1-2.1-0.20.30.30.10.70.1
Reaction time mean minus median AUC0.40.92.91.1-1.50.21.7-1.7-0.5-0.10.0-0.40.2-0.4
Reaction time num false alarms2.43.45.5-2.1-1.1-2.30.8-0.8-1.9-1.9-2.0-1.9-2.3-2.1
Reaction time num false alarms AUC1.92.94.5-2.1-1.1-2.10.8-0.8-1.7-1.8-1.9-1.7-2.1-1.8
Reaction time trials correct on left0.00.00.1-0.20.10.3-0.30.30.20.20.1-0.20.20.2
Reaction time trials on left0.00.00.1-0.10.00.3-0.30.30.10.10.1-0.20.10.2
Reaction time mean1.72.67.00.1-2.6-0.92.6-2.6-1.5-0.9-0.9-1.2-0.5-1.4
Reaction time mean AUC1.21.95.50.5-2.3-0.52.3-2.3-1.1-0.6-0.6-0.8-0.3-1.0
Median of all reaction times2.43.47.1-0.6-2.7-1.42.6-2.6-1.9-1.4-1.4-1.7-1.1-1.9
Reaction time omissions1.52.23.30.3-1.8-1.61.8-1.8-1.4-1.7-1.5-1.0-1.6-0.9
Reaction time false alarm rate2.53.45.9-2.0-1.1-2.41.0-1.0-1.9-2.1-2.1-1.7-2.4-1.9
Reaction time premature initiation rate3.95.48.1-2.8-1.3-2.61.4-1.4-2.5-2.7-2.7-2.1-2.8-2.4
Reaction time premature initiations1.93.45.4-2.3-1.0-2.01.0-1.0-1.9-2.1-2.2-1.8-2.3-1.9
Std. dev. reaction times0.61.13.51.0-1.7-0.21.9-1.9-0.7-0.2-0.1-0.60.0-0.6
Reaction time trials completed0.00.00.1-0.10.00.3-0.30.30.10.10.1-0.20.10.2
Reaction time trials AUC0.00.00.1-0.20.10.3-0.30.30.10.10.1-0.20.10.1
Run reversals in cocaine runway, females0.10.10.5-0.2-0.1-0.20.1-0.10.0-0.2-0.00.00.00.7
Run reversals in cocaine runway, males2.42.44.42.11.31.5-1.31.31.71.31.51.51.22.0
Latency to leave start box in cocaine runway0.80.91.3-0.2-1.1-1.01.1-1.1-0.9-0.9-1.0-0.9-0.9-0.8
Latency to leave start box in cocaine runway, F0.30.30.4-0.2-0.6-0.60.7-0.7-0.5-0.4-0.6-0.6-0.4-0.4
Latency to leave start box in cocaine runway, M0.60.50.70.1-0.9-0.70.9-0.9-0.7-0.7-0.8-0.3-0.8-0.9
Std. dev. time between licks in bursts1.62.24.31.42.01.1-2.12.11.30.90.91.30.51.5
Total sessions with >9 infusions1.92.38.00.62.7-0.2-2.82.80.8-0.4-0.4-0.2-0.80.4
Short access day 1 total inactive lever presses0.60.81.5-0.90.8-1.1-0.60.6-0.5-1.1-1.0-1.0-1.2-0.8
Short access day 10 total inactive lever presses0.40.92.91.10.40.9-0.20.21.00.90.81.11.01.7
Short access day 1 total infusions2.73.612.10.93.50.4-3.43.41.40.20.20.2-0.20.9
Short access day 10 total infusions0.70.93.00.31.70.2-1.71.70.70.10.00.2-0.20.4
Short access total infusions1.21.55.30.42.3-0.0-2.22.20.8-0.2-0.20.0-0.50.6
Short access day 1 locomotion3.03.88.51.62.91.4-2.92.92.01.21.11.40.81.5
Short access day 10 total locomotion1.12.14.50.92.01.2-2.12.11.41.01.21.31.00.8
Short access total locomotion2.02.47.40.72.60.7-2.72.71.30.40.40.80.10.8
One hour access (0.3 mA shock)0.91.01.81.30.71.1-0.70.71.11.11.21.11.00.6
Compulsive drug intake0.50.61.40.7-0.50.90.5-0.50.60.90.91.21.00.9
One hour access (shock baseline)0.40.61.70.61.30.4-1.31.30.60.40.50.20.2-0.3
Social response proportion0.50.61.1-0.3-0.9-1.00.8-0.8-0.8-0.9-0.9-0.3-0.9-0.4
Social responses0.50.61.10.60.90.7-1.01.00.70.40.40.90.31.0
Social time2.83.85.4-1.2-2.3-2.02.2-2.2-2.1-2.1-2.1-1.2-1.9-1.5
Soleus weight0.61.95.30.90.32.30.0-0.01.21.91.91.12.10.0
Bone: stiffness1.62.64.51.12.11.3-2.02.01.71.61.51.51.21.5
Tibialis anterior weight6.120.830.74.83.35.5-3.33.34.85.25.24.95.13.9
Time to tail flick, vehicle, before self-admin0.20.20.60.2-0.5-0.20.8-0.8-0.4-0.3-0.3-0.2-0.3-0.3
Time to tail flick, vehicle, after self-admin1.92.54.6-1.6-0.6-1.70.6-0.6-1.7-1.7-1.7-2.1-1.8-2.1
Time to tail flick, test, before self-admin0.40.41.40.51.2-0.1-1.11.10.4-0.0-0.00.1-0.20.3
Time to tail flick, test, after self-admin1.01.11.8-1.1-1.3-0.91.0-1.0-1.1-0.9-0.9-1.1-0.9-1.3
Delta time to tail flick, vehicle, before/after SA0.60.61.6-1.30.2-0.8-0.50.5-0.6-0.8-0.8-1.1-0.8-0.8
Delta time to tail flick, test, before/after SA1.41.42.8-1.3-1.7-0.81.4-1.4-1.3-1.0-1.0-1.0-0.9-1.3
Tibia length1.95.37.12.02.22.5-2.12.12.52.62.72.32.31.7
Ambulatory time before self-admin0.30.51.40.7-1.20.21.2-1.2-0.20.10.1-0.20.2-0.2
Ambulatory time after self-admin1.72.03.31.8-1.21.41.3-1.30.91.51.51.51.71.6
Bone: tissue strength1.01.02.41.50.51.0-0.30.31.10.90.91.10.91.5
Total heroin consumption0.30.41.5-0.31.2-0.2-1.11.10.2-0.2-0.2-0.4-0.30.1
Bone: trabecular number1.32.17.0-2.6-0.6-1.50.5-0.5-1.4-1.6-1.5-1.5-1.6-1.4
Bone: trabecular spacing0.00.00.10.1-0.0-0.30.1-0.1-0.2-0.2-0.3-0.2-0.2-0.0
Bone: trabecular thickness0.10.20.5-0.70.40.6-0.40.40.20.40.40.50.3-0.2
Bone: trabecular tissue density0.20.30.90.5-0.40.40.3-0.30.40.60.60.71.00.1
Water consumed over 24 hours1.21.64.11.10.41.7-0.40.41.21.81.90.32.00.2
Number of responses in last shaping day5.05.515.61.54.01.3-3.53.52.41.51.41.31.21.7