Hub : Genes

Rab33b

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Rab33b 0.06 0.03 4.3e-06 0.03 0.04 0.03 0.03 3.3e-04 4.4e-05 5.3e-04 2.7e-04
2 Adipose mRNA stability Rab33b 0.02 0.02 9.2e-03 0.01 0 0 0 6.6e-02 1.1e-01 2.1e-01 1.6e-01
3 Brain gene expression Rab33b 0.08 0.04 2.3e-10 0.1 0.11 0.11 0.12 9.9e-10 1.6e-10 9.7e-11 7.9e-11
4 PL isoform ratio NM_001108944.1 0.03 0.02 9.7e-03 0.02 0.01 0.01 0.01 1.6e-03 2.8e-02 7.2e-02 1.9e-02
5 PL isoform ratio XM_063282252.1 0.03 0.02 9.2e-03 0.02 0.01 0.01 0.01 1.3e-03 2.2e-02 5.2e-02 1.4e-02
6 pVTA gene expression Rab33b 0.08 0.04 6.9e-08 0.04 0.05 0.04 0.04 2.1e-04 4.5e-05 3.5e-04 3.1e-04
7 PL gene expression Rab33b 0.08 0.04 7.4e-10 0.09 0.07 0.08 0.08 2.9e-10 2.6e-08 5.3e-09 4.1e-09
8 NAcc gene expression Rab33b 0.12 0.05 0.0e+00 0.15 0.15 0.15 0.15 1.6e-22 7.3e-22 8.2e-22 1.3e-21
9 IC gene expression Rab33b 0.12 0.07 4.6e-05 0.07 0.07 0.05 0.06 6.0e-04 8.9e-04 2.8e-03 1.2e-03
10 Adipose gene expression Rab33b 0.05 0.03 2.6e-05 0.01 0.02 0.02 0.01 2.5e-02 1.8e-03 6.5e-03 7.5e-03
11 BLA gene expression Rab33b 0.1 0.06 1.1e-05 0.1 0.09 0.06 0.09 3.5e-06 3.0e-05 4.1e-04 1.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.22.27.0-2.60.6-1.2-0.60.6-1.61.61.51.6-1.61.5
Area under the delay curve0.20.30.70.0-0.4-0.70.2-0.2-0.40.70.70.7-0.90.3
BMI with tail0.93.14.61.6-2.11.91.9-1.91.8-1.6-1.7-1.81.4-1.3
BMI without tail0.00.10.3-0.2-0.2-0.1-0.10.1-0.10.40.3-0.1-0.50.0
Body weight0.52.34.31.8-2.11.61.7-1.71.5-1.5-1.6-0.81.1-0.8
Weight adjusted by age0.10.20.80.1-0.30.40.3-0.30.5-0.4-0.4-0.20.5-0.9
Bone surface0.51.02.00.3-1.40.91.4-1.40.9-0.8-0.9-0.90.5-0.7
Bone volume0.10.20.6-0.5-0.80.40.8-0.80.3-0.3-0.3-0.30.1-0.0
Breakpoint value in progressive ratio session0.10.20.5-0.5-0.1-0.50.1-0.1-0.20.70.70.5-0.7-0.3
Number of licking bursts0.10.20.30.4-0.50.30.5-0.50.3-0.6-0.5-0.20.50.1
Context. condit. distance diff. score2.32.84.2-2.11.9-1.2-1.81.8-1.71.51.42.0-1.11.6
Locomotion velocity, session 14.34.96.31.8-2.32.32.2-2.22.4-2.1-2.2-2.01.9-2.5
Locomotion distance, session 13.24.15.02.2-2.01.92.0-2.02.1-2.0-2.1-2.11.8-2.2
Locomotion velocity, session 26.57.710.02.7-2.42.72.3-2.33.2-3.1-3.1-2.83.0-2.9
Locomotion distance, session 24.05.78.52.9-1.42.61.5-1.52.6-2.9-2.9-2.32.9-1.8
Locomotion velocity, session 30.50.62.5-0.01.60.3-1.31.3-0.1-0.1-0.1-0.20.60.2
Locomotion distance, session 30.30.41.60.01.30.1-1.01.0-0.40.10.10.10.20.6
Stereotopy head waving bouts, day 30.81.02.41.0-0.50.80.4-0.41.1-1.1-1.1-1.51.1-1.1
Stereotopy head waving duration, day 31.31.63.51.1-0.81.10.7-0.71.4-1.3-1.3-1.91.3-1.7
Locomotion velocity, session 70.50.61.1-0.80.8-0.7-0.60.6-0.80.70.81.0-0.70.8
Locomotion distance, session 71.92.45.2-1.81.5-1.4-1.31.3-1.61.21.31.9-1.12.3
Stereotopy head waving bouts, day 70.70.81.80.9-0.30.80.2-0.21.0-0.9-0.9-1.31.1-1.2
Stereotopy head waving duration, day 70.50.61.70.7-0.10.8-0.00.00.9-0.8-0.8-1.21.0-1.3
Locomotion velocity, session 81.41.62.61.6-0.91.21.1-1.11.5-1.3-1.3-1.31.1-1.5
Locomotion distance, session 80.60.92.61.00.31.2-0.00.00.9-1.3-1.4-0.41.6-0.6
Degree of sensitization distance1.41.63.3-1.70.5-1.2-0.40.4-1.31.11.11.7-1.31.8
Degree of sensitization stereotypy0.10.10.60.2-0.20.20.0-0.00.3-0.2-0.2-0.60.4-0.8
Conditioned locomotion0.40.51.4-0.41.1-0.4-1.21.2-0.70.60.60.4-0.10.4
Cocaine response after cond. corrected0.10.20.3-0.30.4-0.6-0.50.5-0.50.50.40.1-0.30.5
Cocaine response after cond. not corrected0.10.20.4-0.20.3-0.7-0.40.4-0.40.50.4-0.1-0.40.1
Cocaine response before conditioning0.30.40.90.1-0.80.20.9-0.90.6-0.2-0.2-0.7-0.2-0.9
Saline control response0.60.82.81.7-0.41.10.3-0.30.8-0.9-0.8-0.40.9-1.0
Bone: connectivity density0.81.23.6-1.9-0.2-1.10.3-0.3-1.01.31.21.2-1.60.7
Bone: cortical apparent density0.40.72.5-1.61.0-0.2-0.90.9-0.70.50.50.80.00.8
Bone: cortical area1.93.04.21.3-1.91.91.9-1.91.8-1.5-1.6-2.11.2-1.8
Bone: cortical porosity0.40.40.90.9-0.50.30.6-0.60.8-0.5-0.5-0.70.3-0.9
Bone: cortical porosity0.80.81.41.0-1.00.51.1-1.11.0-0.7-0.7-1.00.4-1.2
Bone: cortical thickness0.20.30.90.1-0.60.50.7-0.70.6-0.1-0.2-0.70.0-0.9
Bone: cortical thickness0.00.00.1-0.0-0.2-0.00.1-0.10.2-0.1-0.0-0.20.1-0.3
Bone: cortical tissue density0.40.62.3-1.51.0-0.2-0.90.9-0.70.50.40.80.10.8
Condit. Reinf. active minus inactive responses0.10.10.50.70.20.2-0.20.2-0.0-0.3-0.30.30.20.7
Condit. Reinf. active-inactive response ratio0.80.82.0-0.21.1-0.7-1.01.0-1.00.70.71.1-0.71.4
Condit. Reinf. active responses1.11.44.62.1-0.81.20.7-0.71.2-1.4-1.4-0.81.2-0.6
Condit. Reinf. inactive responses3.95.08.22.9-1.92.21.8-1.82.5-2.4-2.4-2.12.2-2.3
Incentive salience index mean2.12.65.42.3-1.21.81.2-1.21.7-1.9-1.9-1.41.7-1.1
Condit. Reinf. lever presses6.49.612.53.5-2.63.12.5-2.53.4-3.5-3.4-3.33.1-3.0
Condit. Reinf. active minus inactive responses0.10.10.30.30.30.1-0.20.2-0.40.40.40.3-0.40.5
Condit. Reinf. active-inactive response ratio1.42.24.3-0.52.1-0.8-2.02.0-1.51.21.21.5-1.01.7
Condit. Reinf. active responses1.72.53.01.7-1.61.71.7-1.71.5-1.4-1.4-1.71.1-1.5
Condit. Reinf. inactive responses5.68.211.52.4-3.42.43.4-3.42.9-2.5-2.5-3.02.0-3.2
Condit. Reinf. lever presses1.01.43.71.90.01.80.1-0.11.0-1.4-1.3-1.21.5-0.3
Condit. Reinf. lever reinforcers received1.82.53.11.7-1.61.71.7-1.71.5-1.4-1.4-1.81.1-1.5
Conditioned reinforcement - actives0.20.92.7-0.6-1.6-0.41.6-1.60.10.70.70.3-0.90.2
Conditioned reinforcement - inactives0.72.03.70.9-1.91.01.9-1.91.5-0.8-0.9-1.40.9-1.8
Conditioned locomotion1.62.32.91.3-1.61.61.7-1.71.7-1.4-1.4-1.51.3-1.4
Patch foraging indifference point 0 sec0.51.53.10.9-0.81.80.7-0.71.2-1.6-1.6-1.01.7-0.7
Patch foraging indifference point AUC0.10.10.50.70.20.3-0.20.20.2-0.1-0.2-0.40.1-0.7
Delay disc. indifference point, 0s delay0.80.91.6-1.3-0.8-0.90.8-0.8-0.61.01.01.0-1.10.8
Delay disc. indifference point, 16s delay0.10.20.50.7-0.1-0.30.4-0.40.10.30.40.4-0.5-0.6
Delay disc. indifference point, 2s delay0.10.20.40.1-0.5-0.20.7-0.7-0.10.20.20.2-0.40.5
Delay disc. indifference point, 24s delay2.33.74.7-1.51.5-2.1-1.81.8-2.12.02.02.0-2.02.2
Delay disc. indifference point, 4s delay0.30.31.40.2-1.20.00.9-0.90.30.0-0.10.1-0.1-0.5
Delay disc. indifference point, 8s delay0.81.42.6-0.70.3-1.4-0.50.5-1.31.41.51.4-1.61.3
Indifference point function ln k0.00.10.4-0.5-0.30.20.2-0.2-0.1-0.1-0.00.30.10.7
Indifference point function log k0.00.10.4-0.5-0.30.20.2-0.2-0.1-0.1-0.00.30.10.7
Patch foraging total patch changes 0 sec0.41.12.10.6-0.91.50.8-0.81.0-1.3-1.3-0.91.4-0.6
Patch foraging total patch changes 12 sec0.20.30.60.5-0.40.80.3-0.30.6-0.6-0.6-0.50.7-0.7
Patch foraging total patch changes 18 sec0.51.22.21.5-0.61.20.6-0.61.1-1.1-1.2-1.21.1-1.2
Patch foraging total patch changes 24 sec0.31.12.31.5-0.41.50.4-0.41.0-1.3-1.4-1.01.3-0.7
Patch foraging total patch changes 6 sec2.64.46.81.9-1.52.41.5-1.52.3-2.2-2.3-2.32.3-2.6
Patch foraging time to switch 0 sec0.10.30.7-0.20.8-0.9-0.80.8-0.50.40.40.3-0.40.6
Patch foraging water rate 0 sec0.10.20.6-0.5-0.80.70.7-0.70.2-0.2-0.1-0.00.00.0
Patch foraging water rate 12 sec0.10.61.8-0.2-1.30.71.1-1.10.6-0.4-0.3-0.40.2-0.8
Patch foraging water rate 18 sec0.10.20.7-0.1-0.50.80.6-0.60.3-0.3-0.3-0.10.3-0.1
Patch foraging water rate 24 sec0.30.41.3-0.1-0.61.20.5-0.50.6-0.6-0.7-0.10.7-0.6
Patch foraging water rate 6 sec0.10.20.5-0.4-0.70.30.6-0.6-0.0-0.10.10.7-0.20.3
Seeking ratio, delayed vs. immediate footshock0.50.71.7-0.7-0.2-1.00.2-0.2-0.81.01.11.3-1.20.6
Distance traveled before self-admin0.30.61.70.31.2-0.2-1.31.3-0.60.30.30.7-0.20.7
Distance traveled after self-admin0.91.63.11.70.71.4-0.70.71.0-1.4-1.4-1.31.6-1.4
Extensor digitorum longus weight2.49.618.04.2-1.53.91.4-1.43.3-3.3-3.4-3.33.5-3.2
Bone: elastic displacement3.44.210.2-0.73.2-1.4-3.13.1-1.81.71.61.7-1.01.5
Bone: elastic work0.40.51.01.00.80.8-0.80.80.4-0.6-0.5-0.80.9-0.3
Bone: endosteal estimation2.25.56.72.4-2.52.32.3-2.32.4-2.4-2.5-2.62.0-1.9
Bone: endosteal perimeter0.61.42.91.0-1.70.91.4-1.41.1-1.0-1.0-1.30.7-1.0
Epididymis fat weight0.00.20.90.9-0.60.30.5-0.50.2-0.1-0.10.2-0.1-0.3
Delta time in closed arm before/after self-admin1.61.53.6-1.4-0.1-1.5-0.00.0-1.21.41.41.9-1.41.3
Delta time in open arm before/after self-admin0.80.93.00.51.70.3-1.71.7-0.3-0.3-0.3-0.20.50.4
Diff in mean of infusions in LGA sessions0.10.20.50.70.60.3-0.60.60.2-0.3-0.3-0.50.3-0.6
Delay discount exponential model param0.30.40.90.10.20.80.0-0.00.6-0.8-0.9-0.81.0-0.5
Extinction: sum of active levers before priming1.01.52.0-0.51.2-1.3-1.31.3-1.31.11.11.2-1.31.4
Active lever presses in extinction session 60.20.20.5-0.1-0.0-0.60.1-0.1-0.20.60.60.4-0.70.0
Bone: final force2.03.34.21.5-1.82.11.8-1.82.0-1.8-1.8-1.91.6-1.9
Bone: final moment2.64.25.81.8-1.82.41.9-1.92.3-2.1-2.1-2.21.9-2.1
Food consumed during 24 hour testing period0.10.30.80.30.30.7-0.30.30.1-0.7-0.70.40.90.5
Glucose0.61.01.4-1.00.9-1.1-1.01.0-1.10.90.91.0-0.71.2
Heart weight0.71.12.4-1.3-0.7-0.90.7-0.7-0.70.80.91.6-1.21.4
Delay discount hyperbolic model param0.40.51.00.20.30.8-0.10.10.6-0.8-0.9-0.91.0-0.7
Intermittent access intake day 1-15 change0.10.61.91.40.90.8-0.80.80.2-0.7-0.7-0.60.60.5
Intermittent access intake escalation0.10.52.31.50.80.7-0.70.70.2-0.6-0.6-0.50.50.3
Intermittent access intake escalation 20.71.23.31.61.80.6-1.71.7-0.1-0.5-0.6-0.40.60.0
Intermitt. access day 1 inactive lever presses0.22.75.21.1-2.01.12.3-2.31.6-1.0-0.9-1.71.0-2.2
Intermitt. access day 15 inactive lever presses0.10.40.8-0.40.6-0.8-0.60.6-0.50.70.90.9-0.8-0.3
Intermitt. access escalation Index0.92.73.8-1.61.0-1.8-1.11.1-1.81.91.91.7-2.01.8
Intermittent access day 1 total infusions0.51.53.70.7-1.80.71.9-1.91.2-0.6-0.5-0.80.3-1.2
Intermittent access day 15 total infusions0.10.30.80.9-0.80.40.9-0.90.4-0.2-0.2-0.2-0.00.2
Intermittent access terminal intake (last 3 days)0.61.02.41.6-0.61.10.8-0.81.1-1.0-1.0-1.10.7-0.6
Intermittent access total infusions0.60.71.80.7-1.40.51.4-1.40.8-0.3-0.4-0.40.1-0.4
Intermittent access day 1 locomotion0.91.73.70.6-1.70.81.9-1.91.3-0.7-0.7-1.40.6-1.4
Intermittent access day 15 total locomotion0.62.22.81.5-1.41.61.5-1.51.7-1.3-1.4-1.71.3-1.4
Intermittent access total locomotion2.32.83.61.5-1.61.81.7-1.71.9-1.6-1.7-1.81.5-1.6
Intermittent access standard deviation0.00.10.40.60.40.2-0.30.30.1-0.1-0.10.1-0.00.1
Left kidney weight0.00.30.50.70.10.5-0.40.40.4-0.7-0.50.30.7-0.4
Right kidney weight0.10.41.20.60.90.4-1.11.1-0.0-0.5-0.40.20.7-0.0
Cocaine induced anxiety0.10.20.30.30.6-0.4-0.60.6-0.40.10.3-0.0-0.40.4
Post-drug Anxiety0.40.40.80.20.90.5-0.90.90.2-0.7-0.6-0.90.7-0.4
Baseline Anxiety0.71.12.6-0.10.11.2-0.10.11.0-1.1-1.3-1.31.6-1.6
Tail length0.10.30.8-0.00.1-0.7-0.60.6-0.40.70.70.7-0.9-0.0
Length with tail0.20.82.81.7-0.90.90.6-0.61.0-0.9-0.90.00.6-1.0
Length without tail0.94.67.82.8-2.12.22.1-2.12.2-2.4-2.3-1.22.1-1.7
Times rat made contact with spout0.30.40.90.00.80.7-0.80.8-0.2-0.5-0.50.30.71.0
Lifetime Intake0.81.03.20.6-1.80.31.8-1.80.9-0.1-0.2-0.2-0.1-0.5
Liver weight, left0.91.62.21.5-1.21.31.1-1.11.3-1.2-1.2-1.51.1-1.4
Liver weight, right1.73.05.31.4-1.12.01.0-1.02.0-1.9-1.9-2.32.0-2.0
Locomotor activity3.04.78.93.0-2.02.02.0-2.02.2-2.0-1.9-2.41.7-2.4
Locomotor testing distance1.12.66.12.5-1.61.51.6-1.61.6-1.3-1.2-1.51.0-1.9
Locomotor testing rearing0.31.22.31.5-1.20.71.2-1.21.2-0.9-0.7-0.90.7-1.5
Locomotion in novel chamber0.30.40.80.20.50.9-0.60.60.3-0.8-0.6-0.90.80.0
Locomotion in novel chamber post-restriction0.20.62.0-0.3-1.3-0.11.4-1.40.40.10.3-0.4-0.4-0.5
Fecal boli incidents, locomotor time 10.10.20.50.40.2-0.4-0.60.6-0.40.30.40.3-0.40.7
Change in fecal boli incidents, locomotor task0.10.10.3-0.2-0.20.40.4-0.40.3-0.3-0.3-0.50.4-0.2
Time >=10cm from walls, locomotor time 10.00.00.1-0.2-0.20.2-0.00.00.1-0.2-0.2-0.40.3-0.1
Bouts of movement, locomotor time 10.91.12.8-0.9-1.7-0.71.5-1.5-0.10.80.90.8-1.0-0.2
Total resting periods, locomotor time 11.11.23.4-1.0-1.8-0.71.7-1.7-0.10.80.90.8-1.1-0.2
Rest time, locomotor task time 10.61.02.9-1.1-1.7-0.51.5-1.5-0.10.70.80.8-0.80.3
Distance moved, locomotor task time 10.72.06.4-0.32.5-0.9-2.42.4-1.20.70.50.8-0.50.8
Vertical activity count, locomotor time 10.32.27.60.32.6-0.1-2.82.8-0.8-0.2-0.30.10.50.9
Time >=10cm from walls, locomotor time 20.00.10.3-0.3-0.5-0.20.3-0.3-0.10.20.10.6-0.30.4
Bouts of movement, locomotor time 20.72.44.2-2.0-1.5-1.71.3-1.3-0.91.82.01.3-2.10.5
Total resting periods, locomotor time 20.51.93.0-1.6-1.7-1.31.5-1.5-0.51.51.71.0-1.70.1
Rest time, locomotor task time 20.50.92.00.5-1.40.81.3-1.31.0-0.7-0.5-0.70.6-0.9
Distance moved, locomotor task time 21.31.83.4-0.91.8-1.3-1.71.7-1.41.21.11.3-1.10.9
Vertical activity count, locomotor time 20.40.82.90.11.7-0.2-1.71.7-0.5-0.0-0.10.10.20.4
Light reinforcement 10.10.40.70.8-0.80.60.6-0.60.6-0.4-0.4-0.40.4-0.8
Light reinforcement 22.65.97.62.4-2.82.42.6-2.62.6-2.2-2.3-1.62.1-2.7
Bone: marrow area2.45.87.12.4-2.62.42.3-2.32.5-2.5-2.5-2.72.1-1.9
Bone: maximum diameter3.06.17.92.0-2.52.82.3-2.32.6-2.5-2.5-2.82.3-2.4
Bone: maximum force1.22.33.01.4-1.51.71.4-1.41.6-1.6-1.7-1.71.5-1.3
Bone: maximum moment1.63.14.21.7-1.52.01.4-1.41.9-1.9-1.9-2.01.8-1.5
Mean time between licks in bursts0.21.12.51.6-0.71.00.7-0.71.1-1.2-1.2-1.01.2-0.9
Mean num. licks in bursts0.30.71.7-0.71.3-0.2-1.31.3-0.70.60.60.7-0.40.7
Cd content in liver0.20.30.70.0-0.7-0.10.8-0.80.20.20.10.2-0.2-0.8
Co content in liver0.20.20.5-0.10.2-0.6-0.40.4-0.40.70.60.6-0.7-0.0
Cu content in liver0.20.20.50.7-0.60.20.2-0.20.4-0.3-0.4-0.40.4-0.7
Fe content in liver2.02.43.3-1.21.4-1.7-1.61.6-1.71.81.81.3-1.61.1
K content in liver3.43.45.11.6-2.31.72.1-2.12.0-1.7-1.9-1.41.4-1.7
Mg content in liver2.12.44.21.4-2.11.31.8-1.81.6-1.4-1.6-1.01.1-1.4
Mn content in liver0.40.51.2-1.0-0.1-1.00.0-0.0-0.60.80.80.5-1.10.6
Na content in liver2.22.53.11.4-1.81.31.8-1.81.7-1.5-1.8-1.21.5-1.4
Rb content in liver0.20.20.80.9-0.1-0.2-0.20.20.40.0-0.3-0.60.3-0.6
Se content in liver0.10.10.4-0.6-0.1-0.3-0.00.0-0.30.50.40.2-0.60.4
Sr content in liver2.42.13.6-1.61.3-1.5-0.90.9-1.51.71.71.1-1.91.6
Zn content in liver0.30.41.5-0.5-1.20.11.0-1.0-0.1-0.1-0.10.4-0.20.5
Bone: minimum diameter1.53.06.11.4-2.51.42.2-2.21.7-1.3-1.3-1.80.7-1.7
Time in familiar zone, hab. session 11.61.83.91.5-0.01.60.3-0.31.4-1.4-1.4-2.01.6-1.5
Time in novel zone, hab. session 12.12.44.4-1.90.2-1.8-0.40.4-1.61.71.62.1-1.91.7
Total zone transitions, hab. session 12.53.54.42.1-1.72.11.9-1.92.0-1.9-1.9-1.51.6-1.8
Total locomotion distance, hab. session 10.10.20.40.3-0.50.50.6-0.60.5-0.4-0.4-0.40.4-0.3
Locomotion velocity, hab. session 10.00.10.10.3-0.20.30.3-0.30.3-0.2-0.2-0.30.2-0.2
Time in familiar zone, hab. session 20.10.10.50.00.10.7-0.30.30.3-0.1-0.2-0.40.3-0.5
Time in novel zone, hab. session 21.41.52.6-1.01.0-1.6-0.90.9-1.41.21.21.5-1.11.6
Total zone transitions, hab. session 25.67.210.72.5-2.43.32.4-2.42.9-2.8-2.8-2.52.6-2.8
Total locomotion distance, hab. session 20.91.22.70.9-1.01.61.1-1.11.1-1.2-1.1-0.81.1-0.9
Locomotion velocity, hab. session 21.52.13.61.1-1.51.91.5-1.51.4-1.5-1.4-1.21.3-1.3
Novel to familiar place preference ratio0.00.10.3-0.6-0.20.30.3-0.3-0.0-0.0-0.10.10.10.1
Novelty place preference0.00.00.4-0.6-0.20.20.1-0.1-0.1-0.0-0.10.10.10.2
Time in novel zone, NPP test0.10.10.5-0.70.10.1-0.10.1-0.20.10.10.20.10.3
Total zone transitions, NPP test2.23.34.51.9-1.81.81.9-1.91.9-1.6-1.7-1.81.4-2.1
Total locomotion distance, NPP test1.31.83.10.9-1.71.21.8-1.81.3-1.1-1.1-1.10.9-1.3
Locomotion velocity, NPP test1.42.03.21.1-1.71.31.8-1.81.4-1.2-1.2-1.20.9-1.5
Intraocular pressure0.61.02.0-1.00.3-1.1-0.20.2-1.11.11.01.4-1.31.4
Delta distance traveled before/after self-admin2.22.44.81.6-0.31.60.4-0.41.6-1.7-1.7-2.11.9-2.2
Delta ambulatory time before/after self-admin0.81.43.01.3-0.11.20.1-0.11.2-1.3-1.3-1.61.5-1.7
Parametrial fat weight0.92.17.32.7-0.81.50.7-0.71.5-1.5-1.4-1.41.3-1.6
Pavlov. Cond. lever latency7.08.911.6-3.22.3-3.1-2.32.3-3.33.43.33.2-3.22.8
Pavlov. Cond. magazine entry latency0.10.10.30.2-0.30.50.3-0.30.3-0.5-0.3-0.10.40.2
Pavlov. Cond. change in total contacts2.02.22.61.3-1.61.61.6-1.61.5-1.6-1.5-1.31.3-1.1
Pavlov. Cond. index score2.53.24.81.7-1.42.11.4-1.41.9-2.2-2.1-1.72.1-1.3
Pavlov. Cond. latency score3.44.36.02.0-1.82.31.8-1.82.3-2.4-2.3-2.02.3-1.7
Pavlov. Cond. lever contacts5.97.19.52.8-2.22.82.3-2.32.9-3.1-3.0-2.72.8-2.3
Pavlov. Cond. magazine entry number0.30.30.9-0.10.5-0.8-0.30.3-0.40.90.70.0-1.0-0.4
Pavlov. Cond. intertrial magazine entries1.01.21.8-0.71.1-1.3-1.11.1-1.21.11.01.3-0.91.1
Pavlov. Cond. lever-magazine prob. diff.2.43.04.31.7-1.42.01.4-1.41.9-2.1-1.9-1.72.0-1.4
Pavlov. Cond. response bias1.92.44.11.5-1.21.91.1-1.11.6-2.0-1.8-1.41.9-0.9
Pavlov. Cond. lever latency3.34.66.9-2.61.7-2.6-1.81.8-2.22.42.42.1-2.11.6
Pavlov. Cond. magazine entry latency2.43.36.12.4-0.62.40.7-0.71.8-2.2-2.2-1.72.5-1.4
Pavlov. Cond. change in total contacts1.84.56.82.6-2.02.42.1-2.12.1-2.2-2.2-1.81.8-1.6
Pavlov. Cond. index score3.04.88.32.9-1.42.71.5-1.52.2-2.5-2.5-2.02.5-1.6
Pavlov. Cond. latency score2.94.77.92.8-1.52.71.6-1.62.2-2.5-2.5-2.02.4-1.6
Pavlov. Cond. lever contacts3.75.48.62.7-1.72.91.9-1.92.4-2.7-2.6-2.32.4-1.8
Pavlov. Cond. magazine entry number3.14.07.6-2.80.7-2.7-0.90.9-2.02.42.41.7-2.61.4
Pavlov. Cond. intertrial magazine entries0.40.91.9-1.00.8-1.4-0.90.9-0.91.21.20.7-1.10.5
Pavlov. Cond. lever-magazine prob. diff.2.53.96.72.6-1.22.51.3-1.32.0-2.3-2.2-1.82.3-1.5
Pavlov. Cond. response bias4.86.710.03.1-1.93.22.1-2.12.7-2.9-2.8-2.52.7-2.2
Time in closed arm before self-admin0.50.81.50.5-0.51.00.6-0.61.0-1.0-1.0-1.21.1-0.9
Time in closed arm after self-admin0.30.30.7-0.4-0.8-0.40.8-0.8-0.20.40.40.6-0.60.4
Time in open arm before self-admin0.70.81.60.9-1.30.71.2-1.20.8-0.6-0.6-0.50.5-0.9
Time in open arm after self-admin0.70.82.6-0.31.4-0.1-1.61.6-0.70.20.20.3-0.00.8
Bone: periosteal estimation2.86.69.12.4-2.82.62.6-2.62.7-2.5-2.5-3.02.1-2.3
Bone: periosteal perimeter1.32.54.71.1-2.21.21.9-1.91.7-1.2-1.1-1.70.8-2.0
Bone: post-yield work0.10.20.40.6-0.40.20.1-0.10.3-0.5-0.5-0.50.30.3
Progressive ratio test 1 active lever presses0.61.03.00.3-1.70.41.7-1.70.9-0.3-0.3-0.60.1-0.6
Progressive ratio test 1 breakpoint0.71.23.10.5-1.80.61.8-1.81.1-0.5-0.5-0.80.3-0.8
Progressive ratio test 1 inactive lever presses0.41.22.01.0-1.40.71.4-1.41.2-0.8-0.7-1.10.6-1.2
Progressive ratio test 2 active lever presses0.81.23.60.6-1.80.51.9-1.91.0-0.5-0.5-0.60.2-0.2
Progressive ratio test 2 breakpoint0.91.23.50.7-1.80.51.9-1.91.0-0.5-0.5-0.60.3-0.2
Progressive ratio test 2 inactive lever presses0.61.85.41.0-2.30.32.3-2.31.1-0.3-0.3-0.60.1-1.1
Incentive Sensitization - Responses0.41.21.91.2-1.40.81.4-1.41.1-0.9-0.9-1.00.8-0.6
Incentive Sensitization - Breakpoint0.40.81.41.1-1.10.71.2-1.20.9-0.8-0.8-0.80.6-0.4
Sum of active levers in priming session hrs 5-60.20.20.80.80.00.1-0.30.30.4-0.2-0.2-0.60.2-0.9
Progressive ratio0.82.45.0-1.8-0.2-1.90.3-0.3-1.42.02.01.9-2.21.2
Food seeking constrained by brief footshock0.81.12.4-0.7-0.6-0.90.6-0.6-0.91.11.11.3-1.41.6
Seeking ratio, punishment vs. effort0.10.30.70.70.20.8-0.20.20.4-0.8-0.7-0.50.90.1
Retroperitoneal fat weight0.10.64.12.0-0.40.60.4-0.40.6-0.6-0.5-0.00.3-0.7
Reaction time number correct0.00.00.1-0.2-0.10.30.3-0.30.2-0.2-0.10.20.2-0.2
Reaction time mean minus median0.21.54.21.81.90.4-2.12.1-0.2-0.3-0.3-0.10.7-0.1
Reaction time mean minus median AUC0.10.92.91.11.50.2-1.71.7-0.50.1-0.00.40.20.4
Reaction time num false alarms2.03.45.5-2.11.1-2.3-0.80.8-1.91.92.01.9-2.32.1
Reaction time num false alarms AUC1.32.94.5-2.11.1-2.1-0.80.8-1.71.81.91.7-2.11.8
Reaction time trials correct on left0.00.00.1-0.2-0.10.30.3-0.30.2-0.2-0.10.20.2-0.2
Reaction time trials on left0.00.00.1-0.1-0.00.30.3-0.30.1-0.1-0.10.20.1-0.2
Reaction time mean1.22.67.00.12.6-0.9-2.62.6-1.50.90.91.2-0.51.4
Reaction time mean AUC0.81.95.50.52.3-0.5-2.32.3-1.10.60.60.8-0.31.0
Median of all reaction times2.23.47.1-0.62.7-1.4-2.62.6-1.91.41.41.7-1.11.9
Reaction time omissions1.32.23.30.31.8-1.6-1.81.8-1.41.71.51.0-1.60.9
Reaction time false alarm rate2.53.45.9-2.01.1-2.4-1.01.0-1.92.12.11.7-2.41.9
Reaction time premature initiation rate3.55.48.1-2.81.3-2.7-1.41.4-2.52.72.72.1-2.82.4
Reaction time premature initiations1.13.45.4-2.31.0-2.0-1.01.0-1.92.12.21.8-2.31.9
Std. dev. reaction times0.31.13.51.01.7-0.2-1.91.9-0.70.20.10.60.00.6
Reaction time trials completed0.00.00.1-0.1-0.00.30.3-0.30.1-0.1-0.10.20.1-0.2
Reaction time trials AUC0.00.00.1-0.2-0.10.30.3-0.30.1-0.1-0.10.20.1-0.1
Run reversals in cocaine runway, females0.10.10.5-0.20.1-0.2-0.10.10.00.20.0-0.00.0-0.7
Run reversals in cocaine runway, males2.22.44.42.1-1.31.51.3-1.31.7-1.3-1.5-1.51.2-2.0
Latency to leave start box in cocaine runway0.70.91.3-0.21.1-1.0-1.11.1-0.90.91.00.9-0.90.8
Latency to leave start box in cocaine runway, F0.20.30.4-0.20.6-0.6-0.70.7-0.50.40.60.6-0.40.4
Latency to leave start box in cocaine runway, M0.60.50.70.10.9-0.7-0.90.9-0.70.70.80.3-0.80.9
Std. dev. time between licks in bursts1.12.24.31.4-2.01.12.1-2.11.3-0.9-0.9-1.30.5-1.5
Total sessions with >9 infusions1.92.38.00.6-2.7-0.22.8-2.80.80.40.40.2-0.8-0.4
Short access day 1 total inactive lever presses0.40.81.5-0.9-0.8-1.10.6-0.6-0.51.11.01.0-1.20.8
Short access day 10 total inactive lever presses0.10.92.91.1-0.40.90.2-0.21.0-0.9-0.8-1.11.0-1.7
Short access day 1 total infusions1.83.612.10.9-3.50.43.4-3.41.4-0.2-0.2-0.2-0.2-0.9
Short access day 10 total infusions0.50.93.00.3-1.70.21.7-1.70.7-0.1-0.0-0.2-0.2-0.4
Short access total infusions1.11.55.30.4-2.3-0.02.2-2.20.80.20.2-0.0-0.5-0.6
Short access day 1 locomotion2.33.88.51.6-2.91.42.9-2.92.0-1.2-1.1-1.40.8-1.5
Short access day 10 total locomotion0.52.14.50.9-2.01.22.1-2.11.4-1.0-1.2-1.31.0-0.8
Short access total locomotion1.62.47.40.7-2.60.72.7-2.71.3-0.4-0.4-0.80.1-0.8
One hour access (0.3 mA shock)0.81.01.81.3-0.71.10.7-0.71.1-1.1-1.2-1.11.0-0.6
Compulsive drug intake0.40.61.40.70.50.9-0.50.50.6-0.9-0.9-1.21.0-0.9
One hour access (shock baseline)0.20.61.70.6-1.30.41.3-1.30.6-0.4-0.5-0.20.20.3
Social response proportion0.50.61.1-0.30.9-1.0-0.80.8-0.80.90.90.3-0.90.4
Social responses0.50.61.10.6-0.90.71.0-1.00.7-0.4-0.4-0.90.3-1.0
Social time2.43.85.4-1.22.3-2.0-2.22.2-2.12.12.11.2-1.91.5
Soleus weight0.61.95.30.9-0.32.3-0.00.01.2-1.9-1.9-1.12.1-0.0
Bone: stiffness1.42.64.51.1-2.11.32.0-2.01.7-1.6-1.5-1.51.2-1.5
Tibialis anterior weight6.020.830.74.8-3.35.53.3-3.34.8-5.2-5.2-4.95.1-3.9
Time to tail flick, vehicle, before self-admin0.10.20.60.20.5-0.2-0.80.8-0.40.30.30.2-0.30.3
Time to tail flick, vehicle, after self-admin1.22.54.6-1.60.6-1.7-0.60.6-1.71.71.72.1-1.82.1
Time to tail flick, test, before self-admin0.40.41.40.5-1.2-0.11.1-1.10.40.00.0-0.1-0.2-0.3
Time to tail flick, test, after self-admin1.01.11.8-1.11.3-0.9-1.01.0-1.10.90.91.1-0.91.3
Delta time to tail flick, vehicle, before/after SA0.60.61.6-1.3-0.2-0.80.5-0.5-0.60.80.81.1-0.80.8
Delta time to tail flick, test, before/after SA1.21.42.8-1.31.7-0.8-1.41.4-1.31.01.01.0-0.91.3
Tibia length1.95.37.12.0-2.22.52.1-2.12.5-2.6-2.7-2.32.3-1.7
Ambulatory time before self-admin0.10.51.40.71.20.2-1.21.2-0.2-0.1-0.10.20.20.2
Ambulatory time after self-admin1.32.03.31.81.21.4-1.31.30.9-1.5-1.5-1.51.7-1.6
Bone: tissue strength1.01.02.41.5-0.51.00.3-0.31.1-0.9-0.9-1.10.9-1.5
Total heroin consumption0.30.41.5-0.3-1.2-0.21.1-1.10.20.20.20.4-0.3-0.1
Bone: trabecular number1.12.17.0-2.60.6-1.5-0.50.5-1.41.61.51.5-1.61.4
Bone: trabecular spacing0.00.00.10.10.0-0.3-0.10.1-0.20.20.30.2-0.20.0
Bone: trabecular thickness0.10.20.5-0.7-0.40.60.4-0.40.2-0.4-0.4-0.50.30.2
Bone: trabecular tissue density0.20.30.90.50.40.4-0.30.30.4-0.6-0.6-0.71.0-0.1
Water consumed over 24 hours0.81.64.11.1-0.41.70.4-0.41.2-1.8-1.9-0.32.0-0.2
Number of responses in last shaping day4.35.515.61.5-4.01.33.5-3.52.4-1.5-1.4-1.31.2-1.7