Hub : Genes

RT1-Db1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability RT1-Db1 0.22 0.08 0.0e+00 0.19 0.22 0.2 0.22 1.1e-20 2.3e-24 3.2e-22 1.6e-23
2 pVTA alternative polyA XM_063279016.1 0.08 0.05 3.8e-05 0.03 0.06 0.04 0.04 2.5e-03 2.4e-05 7.2e-04 3.1e-04
3 pVTA alternative polyA NM_001008884.2 0.08 0.05 3.1e-05 0.04 0.06 0.04 0.04 7.0e-04 2.0e-05 7.3e-04 1.9e-04
4 PL intron excision ratio chr20_4552734_4555958 0.08 0.04 7.7e-08 0.07 0.06 0.07 0.06 8.1e-08 2.0e-07 4.7e-08 1.3e-07
5 Liver intron excision ratio chr20_4556227_4560005 0.32 0.13 5.6e-16 0.06 0.1 0.11 0.11 3.3e-07 2.8e-11 1.5e-12 9.2e-12
6 Liver mRNA stability RT1-Db1 0.43 0.1 0.0e+00 0.44 0.47 0.48 0.48 2.3e-53 9.1e-58 5.3e-60 5.0e-60
7 Adipose alternative polyA NM_001008884.2 0.25 0.09 0.0e+00 0.27 0.25 0.27 0.16 2.3e-30 8.7e-28 3.1e-30 6.5e-17
8 pVTA mRNA stability RT1-Db1 0.26 0.11 0.0e+00 0.15 0.2 0.2 0.2 3.6e-12 3.9e-16 9.5e-16 9.0e-16
9 Liver alternative polyA NM_001008884.2 0.05 0.03 8.8e-04 0.03 0.02 0.01 0.01 3.9e-04 4.6e-03 1.2e-02 3.1e-02
10 Liver alternative polyA XM_063279016.1 0.06 0.04 4.8e-05 0.04 0.03 0.02 0.01 1.4e-05 3.8e-04 1.2e-03 2.2e-02
11 Liver intron excision ratio chr20_4558455_4560005 0.31 0.12 8.9e-16 0.06 0.1 0.11 0.1 3.9e-07 2.9e-11 2.0e-12 1.8e-11
12 Adipose gene expression RT1-Db1 0.2 0.07 0.0e+00 0.16 0.17 0.16 0.16 1.4e-17 3.0e-18 4.0e-17 4.0e-17
13 Adipose isoform ratio XM_063279016.1 0.62 0.09 0.0e+00 0.54 0.72 0.72 0.72 3.6e-71 1.8e-115 1.3e-114 1.1e-113
14 Adipose isoform ratio NM_001008884.2 0.61 0.09 0.0e+00 0.55 0.72 0.72 0.72 2.3e-72 7.5e-116 4.6e-115 2.3e-114
15 Brain gene expression RT1-Db1 0.45 0.23 0.0e+00 0.19 0.16 0.16 0.17 1.4e-17 6.4e-15 7.2e-15 2.0e-15
16 Brain mRNA stability RT1-Db1 0.07 0.04 6.5e-05 0.03 0.04 0.04 0.02 1.7e-03 8.4e-05 2.0e-04 2.5e-03
17 Adipose alternative polyA XM_063279016.1 0.25 0.09 0.0e+00 0.27 0.25 0.27 0.15 2.6e-30 1.2e-27 1.9e-30 6.0e-16
18 LHb gene expression RT1-Db1 0.88 0.07 2.8e-15 0.27 0.29 0.32 0.31 3.6e-07 1.1e-07 1.9e-08 4.8e-08
19 NAcc gene expression RT1-Db1 0.03 0.02 4.3e-04 0.02 0.02 0.02 0.02 1.5e-04 1.0e-03 3.1e-04 7.7e-04
20 RMTg gene expression RT1-Db1 0.3 0.12 3.1e-05 0.09 0.17 0.17 0.13 2.6e-03 2.7e-05 3.3e-05 2.3e-04
21 pVTA gene expression RT1-Db1 0.38 0.14 0.0e+00 0.22 0.3 0.28 0.29 1.7e-17 4.6e-24 6.0e-23 2.0e-23
22 Liver gene expression RT1-Db1 0.18 0.07 0.0e+00 0.18 0.2 0.19 0.21 1.6e-19 4.5e-22 1.5e-20 8.9e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density1.12.07.0-2.6-0.20.1-1.12.3-2.30.2-2.40.3-0.3-2.4-0.2-1.41.4-1.4-1.70.1-0.9-1.21.01.00.7
Area under the delay curve0.20.41.61.3-0.10.1-0.0-0.80.80.10.80.2-0.20.7-0.51.0-1.00.50.2-0.4-0.5-0.30.30.2-1.1
BMI with tail1.44.812.6-0.8-2.02.02.31.60.0-3.51.3-3.53.5-1.3-0.6-0.10.12.81.93.53.02.0-2.0-1.81.9
BMI without tail0.73.58.81.5-2.32.43.0-0.21.2-2.42.2-2.42.4-0.1-1.62.2-2.22.21.81.81.81.6-0.9-0.8-0.4
Body weight2.08.719.92.4-1.51.63.7-1.23.1-3.64.2-3.63.61.3-0.11.4-1.44.54.03.13.93.3-3.2-3.11.3
Weight adjusted by age0.61.75.41.80.1-0.01.6-1.52.1-0.72.3-0.60.61.80.10.8-0.81.51.60.41.41.8-1.2-1.40.5
Bone surface0.10.20.70.00.6-0.6-0.00.10.80.3-0.00.3-0.3-0.10.8-0.50.50.10.4-0.2-0.00.0-0.5-0.40.6
Bone volume0.10.21.3-0.9-0.10.10.01.0-0.2-0.1-0.7-0.00.0-1.10.1-0.50.5-0.2-0.30.3-0.2-0.40.10.20.5
Breakpoint value in progressive ratio session0.10.10.4-0.00.5-0.5-0.60.20.00.6-0.30.5-0.5-0.10.5-0.30.3-0.5-0.1-0.4-0.4-0.30.00.10.1
Number of licking bursts0.31.03.20.81.6-1.6-0.9-1.60.71.10.31.1-1.11.81.7-0.60.6-0.30.5-1.0-0.1-0.5-0.7-0.6-0.1
Context. condit. distance diff. score3.54.210.8-1.43.2-3.3-3.0-0.3-0.62.3-1.72.4-2.40.63.0-3.13.1-1.5-0.9-1.6-1.4-1.6-0.2-0.41.6
Locomotion velocity, session 11.51.74.40.31.3-1.3-1.4-0.90.02.0-0.82.1-2.10.60.4-0.20.2-1.6-1.2-2.1-1.9-1.51.21.0-0.9
Locomotion distance, session 10.81.13.1-1.80.1-0.2-1.21.5-1.50.4-1.80.5-0.5-1.40.0-1.01.0-1.1-1.3-0.3-0.9-1.00.80.80.3
Locomotion velocity, session 20.30.41.30.00.8-0.8-1.1-0.4-0.10.8-0.50.9-0.90.50.7-0.40.4-0.5-0.2-0.8-0.8-0.80.10.2-0.3
Locomotion distance, session 20.70.93.3-1.70.8-0.9-1.60.7-1.10.2-1.20.3-0.3-0.30.9-1.81.8-0.4-0.70.2-0.2-0.4-0.1-0.21.2
Locomotion velocity, session 30.40.51.40.1-1.01.00.50.5-0.5-0.1-0.4-0.10.1-0.6-1.11.1-1.1-0.4-0.4-0.2-0.5-0.60.81.0-1.2
Locomotion distance, session 31.21.33.5-1.40.3-0.4-1.51.1-1.60.9-1.91.0-1.0-0.90.0-0.80.8-1.7-1.6-0.7-1.4-1.51.11.1-0.1
Stereotopy head waving bouts, day 31.31.54.72.00.5-0.40.8-2.12.0-0.01.9-0.10.12.20.70.8-0.81.21.6-0.21.01.2-1.2-1.1-0.3
Stereotopy head waving duration, day 31.11.35.22.20.1-0.11.1-2.31.70.11.70.1-0.12.1-0.01.3-1.30.81.1-0.60.50.7-0.4-0.5-1.1
Locomotion velocity, session 72.83.19.7-3.11.3-1.4-2.61.5-2.40.8-2.50.8-0.8-1.01.0-2.92.9-1.5-1.90.0-0.9-1.30.60.31.7
Locomotion distance, session 73.24.19.5-2.81.2-1.3-2.81.3-2.71.8-3.11.8-1.8-1.10.4-2.22.2-2.8-2.8-1.0-2.1-2.21.81.50.6
Stereotopy head waving bouts, day 71.41.76.61.8-0.50.50.3-1.90.30.90.30.9-0.91.4-1.02.1-2.1-0.6-0.3-1.6-1.1-1.11.21.3-2.6
Stereotopy head waving duration, day 70.81.03.41.7-0.70.70.8-1.50.60.20.80.2-0.21.2-0.91.8-1.80.00.3-0.9-0.2-0.20.50.6-1.8
Locomotion velocity, session 82.32.88.11.22.8-2.8-1.9-2.01.52.00.42.1-2.12.32.6-1.21.2-0.50.5-1.9-0.8-0.6-0.7-0.90.3
Locomotion distance, session 83.34.815.4-2.33.2-3.3-3.30.6-1.11.8-2.01.8-1.80.13.2-3.93.9-1.2-0.9-0.8-0.9-1.1-0.6-0.92.5
Degree of sensitization distance0.40.51.50.31.2-1.2-0.5-0.80.60.70.40.6-0.60.91.2-0.80.80.00.4-0.30.10.4-0.6-0.70.5
Degree of sensitization stereotypy1.31.54.50.9-0.40.4-0.4-1.1-0.41.1-0.61.1-1.10.6-0.91.4-1.4-1.2-1.0-1.7-1.5-1.81.51.7-2.1
Conditioned locomotion1.11.33.10.40.3-0.30.8-0.11.6-1.01.2-0.90.90.31.1-0.50.51.61.71.11.51.3-1.8-1.71.4
Cocaine response after cond. corrected1.01.54.4-1.40.8-0.8-0.40.9-0.4-0.7-0.1-0.70.7-0.21.5-2.12.10.90.71.41.51.0-1.6-1.62.1
Cocaine response after cond. not corrected0.81.13.00.60.8-0.80.2-0.71.1-0.41.2-0.40.41.11.5-0.70.71.31.60.61.41.2-1.7-1.61.1
Cocaine response before conditioning2.83.314.13.8-0.40.61.7-2.93.00.22.50.2-0.22.3-0.63.0-3.01.01.7-1.10.10.8-0.3-0.1-1.8
Saline control response2.63.69.41.2-3.03.12.90.30.6-2.01.3-2.02.0-0.9-3.03.0-3.01.10.51.20.91.00.70.8-1.6
Bone: connectivity density0.91.45.5-2.30.4-0.4-1.01.9-1.5-0.0-1.60.0-0.0-1.80.6-1.91.9-0.6-0.90.4-0.2-0.30.0-0.01.6
Bone: cortical apparent density1.21.84.3-0.3-2.02.01.71.50.1-2.10.5-2.02.0-1.4-1.40.9-0.91.20.61.91.41.2-0.4-0.20.3
Bone: cortical area0.10.20.70.7-0.00.10.3-0.70.8-0.20.6-0.20.20.50.20.4-0.40.50.70.00.20.0-0.4-0.30.1
Bone: cortical porosity3.33.612.22.0-0.20.2-0.4-1.9-0.22.0-0.21.9-1.91.2-1.42.4-2.4-1.7-1.3-2.5-2.5-2.22.32.3-3.5
Bone: cortical porosity3.03.39.72.10.4-0.4-0.6-2.40.32.20.12.1-2.11.7-0.81.9-2.0-1.5-1.0-2.7-2.4-1.91.91.8-3.1
Bone: cortical thickness0.71.23.9-0.4-2.02.01.11.2-0.8-1.4-0.2-1.31.3-1.5-1.61.1-1.10.3-0.11.00.3-0.20.40.7-0.3
Bone: cortical thickness1.72.05.8-0.4-2.42.41.71.4-0.3-2.20.2-2.12.1-1.5-1.71.2-1.21.00.51.71.10.8-0.10.20.0
Bone: cortical tissue density1.11.73.9-0.2-1.91.91.71.40.2-2.00.6-1.91.9-1.3-1.30.9-0.91.20.71.81.41.2-0.4-0.20.3
Condit. Reinf. active minus inactive responses0.91.12.60.20.1-0.1-1.0-0.5-0.41.3-0.71.2-1.20.1-0.70.6-0.6-1.4-1.3-1.5-1.6-1.01.51.4-1.3
Condit. Reinf. active-inactive response ratio0.50.51.80.6-1.01.00.5-0.0-0.2-0.10.2-0.20.2-0.3-1.31.3-1.3-0.2-0.3-0.3-0.40.20.70.8-1.2
Condit. Reinf. active responses0.50.61.8-0.70.0-0.1-1.10.4-0.80.8-1.00.7-0.7-0.6-0.6-0.20.1-1.2-1.3-0.7-1.2-0.61.21.1-0.3
Condit. Reinf. inactive responses1.21.55.0-2.2-0.10.0-1.32.0-1.80.3-2.00.2-0.2-1.8-0.4-1.21.2-1.3-1.70.2-0.9-0.91.00.90.8
Incentive salience index mean1.11.44.9-0.51.6-1.6-2.2-0.4-0.31.7-1.01.5-1.50.41.0-1.21.2-1.3-1.0-1.3-1.4-1.20.60.40.2
Condit. Reinf. lever presses2.23.310.1-1.52.8-2.9-2.90.1-0.51.7-1.31.5-1.50.42.8-3.23.2-0.9-0.6-0.7-0.7-1.2-0.6-0.92.2
Condit. Reinf. active minus inactive responses0.40.62.71.6-0.20.30.8-1.01.00.21.10.2-0.20.7-0.51.4-1.40.20.5-0.5-0.30.20.10.1-0.9
Condit. Reinf. active-inactive response ratio0.60.94.22.00.5-0.40.7-1.81.40.41.50.5-0.51.50.11.1-1.10.40.8-0.7-0.10.5-0.3-0.3-0.8
Condit. Reinf. active responses0.20.20.90.8-0.30.30.5-0.30.30.20.30.3-0.30.1-0.60.9-0.9-0.4-0.1-0.4-0.5-0.20.50.5-0.7
Condit. Reinf. inactive responses0.20.31.0-0.5-1.01.00.40.9-0.4-0.6-0.4-0.60.6-0.9-0.80.4-0.4-0.1-0.20.50.1-0.10.30.5-0.1
Condit. Reinf. lever presses0.91.33.2-0.00.0-0.1-0.7-0.1-1.11.1-1.01.3-1.3-0.3-0.70.5-0.5-1.7-1.4-1.4-1.8-1.81.61.5-1.2
Condit. Reinf. lever reinforcers received0.30.41.00.9-0.20.20.3-0.50.20.60.20.6-0.60.2-0.61.0-1.0-0.7-0.2-0.8-0.8-0.40.70.7-1.0
Conditioned reinforcement - actives0.00.20.8-0.6-0.30.3-0.00.9-0.5-0.1-0.4-0.10.1-0.8-0.5-0.20.1-0.4-0.50.3-0.3-0.40.50.30.1
Conditioned reinforcement - inactives0.00.10.4-0.1-0.20.2-0.1-0.0-0.30.1-0.10.1-0.10.0-0.70.1-0.2-0.5-0.6-0.1-0.2-0.20.60.3-0.3
Conditioned locomotion0.10.10.3-0.20.4-0.4-0.30.0-0.10.4-0.10.4-0.4-0.1-0.1-0.30.4-0.4-0.5-0.3-0.5-0.40.40.10.2
Patch foraging indifference point 0 sec0.82.25.31.1-2.32.32.20.50.7-1.71.4-1.71.7-0.7-2.22.2-2.21.00.71.30.91.10.10.2-1.0
Patch foraging indifference point AUC0.20.52.11.4-0.20.30.4-0.80.80.50.70.5-0.50.4-0.41.4-1.3-0.00.3-0.8-0.50.00.20.4-1.2
Delay disc. indifference point, 0s delay0.30.31.00.41.0-1.0-0.7-0.70.70.20.50.3-0.31.00.8-0.60.60.40.40.0-0.1-0.0-0.5-0.70.1
Delay disc. indifference point, 16s delay0.30.41.50.2-0.90.90.20.3-0.3-0.3-0.1-0.20.2-0.5-1.21.0-1.00.1-0.5-0.1-0.5-0.40.90.8-1.0
Delay disc. indifference point, 2s delay0.91.04.02.00.8-0.8-0.2-1.71.60.81.30.9-0.91.60.20.9-0.90.40.5-1.0-0.60.0-0.0-0.2-1.1
Delay disc. indifference point, 24s delay0.71.13.51.6-0.60.60.6-1.30.80.30.90.4-0.41.0-1.41.9-1.9-0.1-0.2-0.9-0.7-0.21.00.8-1.9
Delay disc. indifference point, 4s delay0.80.93.92.0-0.30.40.8-1.01.4-0.21.6-0.20.20.8-0.41.5-1.51.11.00.00.20.4-0.3-0.3-1.1
Delay disc. indifference point, 8s delay0.10.20.60.7-0.00.0-0.4-0.50.40.20.40.2-0.20.5-0.50.6-0.60.2-0.2-0.4-0.7-0.40.50.3-0.8
Indifference point function ln k0.20.61.60.51.0-1.0-0.9-1.20.50.9-0.11.0-1.01.30.8-0.20.2-0.4-0.1-1.0-0.6-0.80.00.0-0.1
Indifference point function log k0.20.61.60.51.0-1.0-0.9-1.20.50.9-0.11.0-1.01.30.8-0.20.2-0.4-0.1-1.0-0.6-0.80.00.0-0.1
Patch foraging total patch changes 0 sec0.82.35.81.0-2.42.42.20.50.5-1.81.3-1.71.7-0.7-2.32.2-2.21.00.61.30.91.00.20.3-1.1
Patch foraging total patch changes 12 sec1.21.64.11.0-1.92.01.90.60.6-1.21.0-1.21.2-0.8-1.82.0-2.00.80.60.80.71.00.20.4-0.8
Patch foraging total patch changes 18 sec1.22.77.0-0.9-2.72.61.82.1-1.0-2.50.2-2.42.4-1.9-2.11.0-1.01.10.22.21.21.3-0.00.2-0.1
Patch foraging total patch changes 24 sec0.51.65.0-1.4-1.91.80.42.0-1.8-1.0-1.0-1.01.0-2.2-2.00.6-0.6-0.4-1.11.1-0.3-0.31.21.2-0.5
Patch foraging total patch changes 6 sec1.11.95.20.6-2.32.31.80.8-0.0-1.70.9-1.51.5-1.2-2.31.9-1.90.80.21.20.70.60.50.5-1.0
Patch foraging time to switch 0 sec0.62.46.5-1.9-0.70.70.81.7-0.9-2.1-0.1-2.22.2-1.10.2-1.51.51.50.72.52.21.5-1.4-1.42.1
Patch foraging water rate 0 sec0.10.31.00.8-0.20.20.5-0.70.7-0.41.0-0.30.30.5-0.20.5-0.50.50.60.20.40.8-0.3-0.4-0.2
Patch foraging water rate 12 sec0.10.41.2-0.8-0.90.80.11.0-1.0-0.5-0.8-0.30.3-1.1-0.80.2-0.2-0.4-0.60.3-0.2-0.50.60.7-0.5
Patch foraging water rate 18 sec0.10.30.60.2-0.80.80.60.30.1-0.80.5-0.80.8-0.4-0.60.6-0.60.40.40.60.40.6-0.1-0.1-0.3
Patch foraging water rate 24 sec0.20.30.8-0.2-0.80.80.70.9-0.1-0.7-0.0-0.60.6-0.9-0.60.4-0.40.10.10.50.20.40.00.2-0.2
Patch foraging water rate 6 sec0.20.30.7-0.3-0.80.80.50.7-0.2-0.90.1-0.80.8-0.6-0.40.2-0.20.50.30.80.50.3-0.2-0.10.1
Seeking ratio, delayed vs. immediate footshock1.01.46.01.9-1.51.61.80.11.1-0.61.2-0.50.5-0.3-1.02.5-2.40.61.2-0.1-0.00.5-0.20.4-1.3
Distance traveled before self-admin0.51.23.1-0.50.4-0.40.30.90.5-0.90.6-0.90.9-0.41.3-1.21.21.31.31.31.01.3-1.7-1.61.8
Distance traveled after self-admin0.71.33.41.6-0.50.61.6-0.51.6-0.91.7-0.90.90.40.21.1-1.11.61.80.51.21.5-1.3-1.00.0
Extensor digitorum longus weight0.10.51.80.21.2-1.2-0.4-0.50.80.20.50.3-0.30.71.3-1.01.00.50.6-0.10.2-0.1-0.9-1.01.0
Bone: elastic displacement0.70.92.90.1-0.80.8-0.10.3-1.20.3-0.50.3-0.3-0.5-1.51.1-1.1-0.9-1.1-0.6-1.0-1.01.51.4-1.7
Bone: elastic work0.10.10.40.4-0.50.50.3-0.1-0.1-0.20.3-0.20.20.1-0.60.7-0.70.1-0.00.1-0.1-0.20.30.2-0.6
Bone: endosteal estimation2.05.016.13.41.8-1.71.2-3.64.00.23.40.2-0.23.62.10.4-0.42.13.0-0.31.52.0-2.5-2.50.4
Bone: endosteal perimeter1.33.27.81.82.5-2.4-0.4-2.72.70.81.80.9-0.92.82.8-1.01.01.12.0-0.70.70.9-2.1-2.21.1
Epididymis fat weight2.914.734.8-3.3-5.45.33.85.2-2.7-5.9-0.3-5.95.9-4.9-3.70.6-0.72.90.55.83.52.3-0.6-0.31.6
Delta time in closed arm before/after self-admin0.50.41.30.20.3-0.30.4-0.00.7-0.60.8-0.60.60.30.6-0.50.50.80.90.80.90.3-1.0-1.10.8
Delta time in open arm before/after self-admin0.20.20.7-0.1-0.60.60.20.2-0.40.0-0.4-0.00.0-0.3-0.80.5-0.5-0.4-0.6-0.2-0.3-0.10.70.8-0.6
Diff in mean of infusions in LGA sessions0.71.34.2-1.81.0-1.1-1.81.1-1.20.4-1.40.4-0.4-0.71.2-2.02.0-0.7-0.70.2-0.4-0.2-0.2-0.21.5
Delay discount exponential model param0.40.52.1-1.40.1-0.2-0.00.9-0.9-0.2-0.9-0.30.3-0.80.6-1.21.2-0.4-0.20.50.60.4-0.4-0.31.3
Extinction: sum of active levers before priming0.30.51.50.11.2-1.2-1.0-0.40.50.70.10.7-0.70.51.2-0.90.90.10.2-0.4-0.10.1-0.5-0.60.6
Active lever presses in extinction session 60.40.41.0-0.9-0.20.1-0.60.8-0.9-0.0-0.7-0.10.1-0.9-0.6-0.50.4-0.5-1.00.1-0.8-0.70.80.50.1
Bone: final force1.72.76.40.4-1.51.52.10.30.9-2.51.7-2.42.4-0.2-0.60.6-0.62.21.82.32.32.2-1.6-1.41.0
Bone: final moment1.11.84.50.3-1.31.31.80.20.6-2.11.4-2.02.0-0.1-0.60.6-0.61.81.41.91.81.7-1.2-1.10.6
Food consumed during 24 hour testing period0.91.74.20.20.7-0.60.5-0.51.2-1.01.3-1.01.00.91.4-1.01.01.81.71.31.81.7-2.0-2.11.7
Glucose3.25.114.61.63.8-3.7-2.0-3.52.02.70.92.7-2.73.82.9-1.51.5-0.70.4-2.4-0.9-0.3-0.7-1.10.6
Heart weight1.01.77.02.7-0.30.31.2-2.22.00.12.10.1-0.11.6-0.72.0-2.00.81.0-0.7-0.10.4-0.0-0.1-1.3
Delay discount hyperbolic model param0.50.72.7-1.60.1-0.1-0.01.0-1.0-0.3-0.9-0.40.4-0.80.6-1.31.4-0.4-0.20.60.70.4-0.4-0.41.5
Intermittent access intake day 1-15 change0.00.20.60.6-0.40.40.5-0.50.4-0.00.3-0.00.00.2-0.30.8-0.80.20.2-0.20.10.20.10.2-0.7
Intermittent access intake escalation0.10.72.40.6-1.31.30.9-0.1-0.0-0.30.1-0.40.4-0.5-1.41.5-1.5-0.0-0.1-0.1-0.2-0.10.70.9-1.4
Intermittent access intake escalation 20.20.31.00.70.0-0.0-0.0-1.00.40.50.10.5-0.50.6-0.10.6-0.6-0.3-0.1-0.7-0.3-0.70.40.3-0.9
Intermitt. access day 1 inactive lever presses0.11.65.10.61.7-1.7-0.5-1.31.20.40.90.4-0.41.82.3-1.31.30.61.4-0.01.31.0-1.8-1.71.1
Intermitt. access day 15 inactive lever presses0.10.31.00.60.00.00.5-0.60.7-0.30.8-0.30.30.70.10.2-0.20.70.70.20.61.0-0.6-0.60.2
Intermitt. access escalation Index0.41.13.5-1.11.3-1.3-1.71.0-0.60.5-1.00.5-0.5-0.71.8-1.91.9-0.5-0.00.1-0.3-0.2-0.7-0.51.5
Intermittent access day 1 total infusions0.61.95.1-1.40.8-0.9-1.70.7-1.61.4-1.71.4-1.4-0.7-0.4-1.01.0-2.1-2.3-1.1-1.7-1.81.81.3-0.3
Intermittent access day 15 total infusions0.40.92.6-0.5-0.60.6-0.30.5-1.10.4-0.90.4-0.4-1.0-1.30.5-0.5-1.3-1.5-0.6-1.0-1.11.61.4-1.1
Intermittent access terminal intake (last 3 days)0.50.82.6-0.0-0.50.5-0.20.1-0.70.6-0.60.6-0.6-0.6-1.40.8-0.8-1.3-1.4-0.8-1.2-1.01.61.4-1.3
Intermittent access total infusions0.81.02.9-0.5-0.20.1-0.50.4-1.10.8-1.00.8-0.8-0.6-1.20.2-0.2-1.5-1.7-0.8-1.2-1.21.71.4-1.1
Intermittent access day 1 locomotion0.20.41.5-1.1-0.20.1-0.31.2-1.0-0.0-0.8-0.00.0-1.2-0.6-0.50.5-0.7-1.00.3-0.6-0.20.70.40.3
Intermittent access day 15 total locomotion0.10.51.30.5-0.70.71.10.30.6-0.80.9-0.90.9-0.5-0.70.7-0.70.70.60.60.50.8-0.3-0.30.2
Intermittent access total locomotion0.30.31.3-0.2-0.80.80.60.8-0.4-0.4-0.1-0.40.4-0.9-1.10.6-0.5-0.3-0.50.3-0.20.00.70.5-0.3
Intermittent access standard deviation0.31.64.20.8-1.71.72.1-0.30.7-1.61.3-1.61.60.0-1.41.5-1.51.10.91.11.41.5-0.3-0.3-0.7
Left kidney weight0.86.614.42.1-2.42.63.8-0.12.3-3.43.2-3.43.4-0.2-1.22.3-2.33.73.12.72.92.4-2.1-1.80.3
Right kidney weight1.07.015.11.7-2.12.23.70.12.3-3.63.3-3.53.50.0-0.61.6-1.53.93.43.13.52.9-2.6-2.31.1
Cocaine induced anxiety0.20.61.9-0.20.7-0.7-0.40.40.6-0.20.2-0.20.20.01.4-1.01.00.70.90.50.80.8-1.2-1.11.2
Post-drug Anxiety0.30.41.10.30.2-0.10.30.30.6-0.40.6-0.40.4-0.00.7-0.20.20.91.00.70.70.9-1.0-0.90.7
Baseline Anxiety0.10.10.40.5-0.30.30.5-0.60.3-0.20.5-0.20.20.4-0.50.6-0.60.20.10.0-0.10.40.10.1-0.5
Tail length1.15.924.65.00.5-0.32.0-4.34.10.43.90.4-0.43.80.32.9-2.91.72.7-1.30.61.4-1.3-1.2-1.8
Length with tail1.77.623.04.70.6-0.42.5-4.14.8-0.74.8-0.80.84.00.92.1-2.13.23.80.02.02.5-2.5-2.6-0.3
Length without tail1.68.119.11.90.4-0.32.4-1.63.4-2.73.9-2.72.72.21.7-0.40.44.44.12.84.03.4-3.9-4.12.5
Times rat made contact with spout1.61.94.6-0.6-1.61.5-0.21.0-1.50.1-1.3-0.00.0-1.4-2.11.3-1.3-1.3-1.7-0.5-1.3-1.32.02.1-1.9
Lifetime Intake0.60.72.2-0.4-0.20.1-0.50.5-0.90.6-0.70.6-0.6-0.6-1.10.2-0.2-1.2-1.5-0.7-1.1-1.01.51.2-1.0
Liver weight, left1.52.65.91.81.4-1.30.7-1.72.3-0.22.3-0.10.12.22.0-0.30.31.82.40.31.61.8-2.3-2.31.1
Liver weight, right1.62.87.62.22.0-1.9-0.0-2.42.80.52.30.5-0.52.62.2-0.40.41.22.1-0.30.81.3-1.9-2.10.9
Locomotor activity0.81.25.82.4-0.20.31.0-1.31.70.11.60.1-0.11.10.11.8-1.80.71.4-0.80.30.7-0.6-0.3-1.2
Locomotor testing distance0.20.62.01.40.2-0.10.6-0.61.3-0.11.2-0.10.10.80.60.7-0.70.81.3-0.10.70.8-1.0-0.7-0.2
Locomotor testing rearing0.31.13.01.00.3-0.21.0-0.41.5-0.81.5-0.70.70.70.90.0-0.01.31.70.71.41.7-1.6-1.50.7
Locomotion in novel chamber0.10.10.3-0.1-0.40.40.30.20.3-0.5-0.1-0.50.5-0.3-0.20.2-0.20.30.10.50.5-0.3-0.00.1-0.1
Locomotion in novel chamber post-restriction0.31.02.90.4-1.01.01.40.60.6-1.41.1-1.31.3-0.7-0.60.6-0.61.71.01.21.11.1-0.7-0.70.3
Fecal boli incidents, locomotor time 10.20.52.0-1.40.5-0.6-0.60.6-0.80.2-0.90.1-0.1-0.30.4-1.41.4-0.4-0.80.30.1-0.40.2-0.01.2
Change in fecal boli incidents, locomotor task1.41.54.01.90.7-0.60.5-1.62.0-0.11.90.1-0.11.81.00.5-0.51.21.8-0.11.11.6-1.5-1.40.1
Time >=10cm from walls, locomotor time 12.93.68.91.00.5-0.41.2-0.22.4-1.42.3-1.61.60.81.8-0.70.72.92.91.92.42.4-3.0-2.82.2
Bouts of movement, locomotor time 10.10.20.4-0.20.1-0.1-0.40.1-0.50.5-0.70.5-0.5-0.20.2-0.10.1-0.6-0.3-0.5-0.4-0.60.30.5-0.2
Total resting periods, locomotor time 10.10.20.4-0.10.3-0.3-0.4-0.2-0.40.6-0.50.6-0.60.00.3-0.10.1-0.5-0.3-0.6-0.5-0.40.20.3-0.2
Rest time, locomotor task time 10.20.31.20.40.7-0.7-0.4-0.90.10.8-0.10.8-0.80.80.6-0.20.2-0.3-0.1-0.6-0.5-1.10.10.1-0.3
Distance moved, locomotor task time 10.20.62.40.5-0.80.81.00.20.7-0.81.0-0.90.9-0.2-0.60.7-0.70.90.70.50.91.5-0.5-0.40.0
Vertical activity count, locomotor time 10.21.44.50.4-1.31.31.50.60.5-1.71.2-1.71.7-0.4-0.90.9-0.91.41.01.11.52.1-0.8-0.60.1
Time >=10cm from walls, locomotor time 20.72.05.91.80.4-0.41.0-1.62.4-0.62.4-0.60.62.00.60.5-0.51.81.90.71.62.1-1.6-1.70.6
Bouts of movement, locomotor time 20.10.51.61.2-0.10.20.2-0.70.50.60.30.6-0.60.4-0.31.3-1.3-0.40.1-0.8-0.3-0.30.40.7-1.3
Total resting periods, locomotor time 20.20.92.41.50.3-0.3-0.1-1.00.71.20.21.2-1.20.70.01.3-1.3-0.7-0.0-1.4-0.8-0.70.50.8-1.6
Rest time, locomotor task time 20.71.25.30.01.8-1.7-0.8-0.80.70.50.20.4-0.41.02.3-1.61.60.50.9-0.00.5-0.0-1.5-1.41.2
Distance moved, locomotor task time 20.60.92.3-0.2-1.31.31.20.50.0-1.20.7-1.41.4-0.5-1.50.7-0.70.70.11.01.01.30.1-0.10.0
Vertical activity count, locomotor time 20.30.71.80.2-0.90.91.10.20.3-1.11.0-1.21.2-0.2-1.10.7-0.60.90.40.91.01.3-0.1-0.30.2
Light reinforcement 10.52.36.5-0.5-0.60.71.20.80.5-2.01.0-2.02.0-0.20.6-0.60.61.81.82.22.62.5-2.1-1.81.5
Light reinforcement 20.71.64.4-0.30.3-0.30.40.10.4-1.31.0-1.41.40.41.0-1.11.11.51.51.52.11.9-1.9-1.91.6
Bone: marrow area2.15.216.93.41.7-1.51.4-3.54.10.03.50.0-0.03.52.10.5-0.52.33.1-0.21.62.1-2.5-2.60.4
Bone: maximum diameter0.91.84.91.32.1-2.1-1.0-2.21.81.30.81.3-1.32.12.0-0.70.70.20.8-1.2-0.2-0.3-0.9-1.00.4
Bone: maximum force0.71.42.90.4-0.80.81.50.01.0-1.71.3-1.61.60.0-0.20.3-0.31.61.41.51.61.5-1.2-1.20.8
Bone: maximum moment0.40.81.60.4-0.50.61.2-0.20.8-1.31.1-1.11.10.2-0.20.3-0.31.21.01.11.21.1-0.9-0.90.5
Mean time between licks in bursts0.42.36.20.92.5-2.5-1.5-1.71.12.1-0.02.2-2.21.82.2-1.01.0-0.90.2-1.9-1.2-1.0-0.4-0.40.4
Mean num. licks in bursts0.82.17.1-0.9-2.32.30.82.0-1.4-1.0-0.8-1.11.1-2.3-2.71.3-1.3-0.3-1.30.7-0.5-0.21.61.6-1.0
Cd content in liver1.11.24.1-2.0-0.1-0.00.01.7-0.9-1.0-0.5-1.01.0-1.30.0-1.71.70.4-0.31.41.11.2-0.4-0.81.7
Co content in liver1.31.54.3-0.3-1.21.21.40.70.3-2.10.9-1.91.9-0.6-0.70.2-0.21.50.91.71.71.6-0.9-0.91.0
Cu content in liver1.31.64.4-1.2-1.41.4-0.31.9-1.9-0.2-1.5-0.10.1-2.1-1.70.6-0.6-1.2-1.50.1-1.1-0.81.51.6-1.1
Fe content in liver0.60.71.8-0.6-1.11.11.01.1-0.5-1.20.1-1.21.2-1.0-0.80.2-0.20.80.11.30.90.5-0.1-0.10.2
K content in liver0.50.51.3-1.10.6-0.6-1.00.8-0.70.3-1.10.5-0.5-0.70.7-1.11.1-0.7-0.6-0.3-0.5-0.90.20.20.5
Mg content in liver1.21.44.8-0.22.0-2.0-1.7-0.30.41.1-0.51.2-1.20.52.2-1.71.7-0.60.1-0.9-0.5-0.6-0.7-0.60.9
Mn content in liver2.12.38.00.32.6-2.6-1.5-1.31.70.90.50.8-0.81.82.8-2.02.00.41.0-0.40.40.3-1.6-1.71.6
Na content in liver0.40.41.00.0-0.90.90.10.7-0.80.0-0.50.0-0.0-0.9-0.80.9-0.9-0.4-0.4-0.2-0.6-0.70.70.9-1.0
Rb content in liver0.40.52.2-1.10.7-0.8-0.50.7-0.4-0.1-0.50.0-0.0-0.50.8-1.51.50.0-0.20.50.30.2-0.4-0.61.2
Se content in liver2.02.35.61.62.1-2.1-1.7-2.41.12.10.32.2-2.22.31.6-0.20.2-0.90.0-2.2-1.3-0.90.00.1-0.9
Sr content in liver0.20.20.40.10.7-0.70.2-0.40.3-0.00.5-0.00.00.40.5-0.50.60.30.30.10.40.2-0.4-0.70.3
Zn content in liver0.30.30.8-0.20.9-0.9-0.4-0.60.60.00.20.1-0.10.70.8-0.90.90.00.2-0.10.30.5-0.5-0.70.8
Bone: minimum diameter1.12.25.21.61.9-1.8-0.2-2.32.20.41.70.4-0.42.32.2-0.70.71.21.8-0.30.60.9-1.8-1.91.1
Time in familiar zone, hab. session 12.42.76.3-1.7-1.41.3-0.61.7-2.50.3-2.30.3-0.3-2.0-2.10.5-0.5-1.9-2.5-0.4-1.7-1.92.52.4-1.0
Time in novel zone, hab. session 11.82.05.41.90.9-0.81.0-1.62.3-0.32.2-0.30.31.81.40.2-0.21.62.20.21.51.7-1.9-1.90.3
Total zone transitions, hab. session 10.20.30.8-0.60.5-0.5-0.80.6-0.80.6-0.90.6-0.6-0.50.6-0.70.7-0.6-0.4-0.4-0.4-0.60.10.20.1
Total locomotion distance, hab. session 10.40.51.2-1.10.6-0.6-0.90.9-0.90.4-1.10.4-0.4-0.80.8-1.11.1-0.5-0.4-0.1-0.4-0.7-0.00.10.7
Locomotion velocity, hab. session 10.20.30.7-0.60.4-0.4-0.70.6-0.70.4-0.80.4-0.4-0.60.6-0.70.7-0.5-0.4-0.2-0.5-0.70.10.20.3
Time in familiar zone, hab. session 20.60.62.1-0.3-1.41.40.81.3-0.7-0.8-0.4-0.80.8-1.3-0.90.9-0.90.10.10.60.20.20.20.6-0.3
Time in novel zone, hab. session 20.20.31.70.60.4-0.40.0-1.30.60.40.60.4-0.41.1-0.20.2-0.2-0.1-0.2-0.4-0.10.10.3-0.1-0.7
Total zone transitions, hab. session 20.50.62.0-1.00.0-0.0-0.21.4-0.5-0.6-0.4-0.60.6-1.10.8-1.01.00.60.51.00.70.4-0.9-0.71.1
Total locomotion distance, hab. session 21.01.34.0-2.00.5-0.5-1.01.9-1.2-0.3-1.3-0.30.3-1.51.3-2.02.00.0-0.10.90.3-0.2-0.8-0.61.5
Locomotion velocity, hab. session 21.01.44.6-2.00.8-0.9-1.41.7-1.20.1-1.50.1-0.1-1.31.5-2.12.2-0.2-0.30.6-0.1-0.5-0.7-0.51.6
Novel to familiar place preference ratio0.20.30.80.10.2-0.2-0.3-0.4-0.20.6-0.30.6-0.60.4-0.30.2-0.2-0.7-0.7-0.6-0.6-0.50.80.6-0.9
Novelty place preference0.30.41.40.50.2-0.2-0.2-0.70.00.7-0.10.7-0.70.6-0.40.5-0.5-0.7-0.5-0.8-0.6-0.50.80.6-1.2
Time in novel zone, NPP test0.40.41.90.70.1-0.1-0.1-0.90.20.70.10.8-0.80.7-0.50.7-0.7-0.6-0.5-0.9-0.6-0.50.80.7-1.4
Total zone transitions, NPP test1.01.54.0-1.91.1-1.2-1.71.2-1.40.8-1.70.9-0.9-1.01.1-2.02.0-1.0-1.1-0.4-0.8-0.90.20.10.9
Total locomotion distance, NPP test1.42.07.0-2.61.0-1.1-1.61.8-1.70.2-1.70.2-0.2-1.51.1-2.62.6-0.6-1.00.5-0.2-0.6-0.1-0.31.6
Locomotion velocity, NPP test1.92.79.4-3.11.2-1.3-1.92.0-2.10.3-2.10.3-0.3-1.71.4-3.13.1-0.7-1.20.6-0.3-0.8-0.2-0.31.9
Intraocular pressure0.40.72.6-1.4-0.80.80.21.6-1.4-0.4-1.0-0.30.3-1.6-0.9-0.20.2-0.3-0.90.5-0.30.10.60.60.4
Delta distance traveled before/after self-admin1.71.86.72.4-0.91.01.3-1.91.20.31.30.3-0.31.2-1.32.6-2.6-0.00.4-1.0-0.20.10.70.8-2.3
Delta ambulatory time before/after self-admin1.01.75.92.4-0.60.71.2-1.91.50.31.40.3-0.31.3-0.92.4-2.40.10.7-1.0-0.00.50.30.5-2.1
Parametrial fat weight2.04.711.9-1.3-1.91.92.02.0-0.5-3.40.8-3.43.4-1.7-0.5-0.50.52.91.63.42.92.2-1.9-1.71.9
Pavlov. Cond. lever latency4.25.311.90.1-3.13.23.21.50.2-3.51.6-3.43.4-1.4-2.11.7-1.72.31.72.92.72.9-1.1-0.80.3
Pavlov. Cond. magazine entry latency2.33.07.61.01.7-1.7-2.1-1.60.12.8-0.82.6-2.61.30.70.2-0.2-2.0-1.2-2.7-2.4-2.31.31.3-1.5
Pavlov. Cond. change in total contacts1.31.43.61.11.2-1.2-1.3-1.40.61.9-0.21.8-1.81.10.50.3-0.3-1.2-0.6-1.9-1.6-1.30.80.7-1.0
Pavlov. Cond. index score3.44.310.10.42.7-2.7-3.0-1.70.13.2-1.23.1-3.11.51.7-1.11.0-2.1-1.3-2.8-2.5-2.71.10.8-0.7
Pavlov. Cond. latency score3.54.510.70.52.8-2.8-3.0-1.70.13.3-1.23.2-3.21.51.8-1.11.1-2.1-1.3-2.9-2.6-2.81.00.8-0.7
Pavlov. Cond. lever contacts3.34.010.0-0.33.1-3.2-3.0-1.2-0.02.8-1.22.7-2.71.32.4-2.22.1-1.5-1.1-2.1-1.8-2.10.40.00.5
Pavlov. Cond. magazine entry number1.72.15.5-0.7-1.41.41.71.3-0.1-2.30.8-2.12.1-1.1-0.7-0.00.01.71.02.32.02.0-1.1-1.11.1
Pavlov. Cond. intertrial magazine entries1.01.23.8-1.7-1.31.30.71.9-1.0-1.4-0.6-1.31.3-1.7-1.2-0.40.40.2-0.61.50.80.80.20.10.8
Pavlov. Cond. lever-magazine prob. diff.3.44.29.70.32.6-2.7-3.0-1.6-0.03.1-1.33.0-3.01.41.6-1.11.1-2.1-1.4-2.7-2.5-2.71.10.9-0.6
Pavlov. Cond. response bias2.32.97.00.42.2-2.2-2.4-1.40.02.7-0.92.5-2.51.41.4-0.80.8-1.7-1.1-2.4-2.0-2.10.80.7-0.5
Pavlov. Cond. lever latency0.81.12.70.30.9-0.90.2-0.41.4-0.31.0-0.40.40.81.5-0.90.91.31.40.61.21.5-1.6-1.61.4
Pavlov. Cond. magazine entry latency0.30.50.90.10.9-0.9-0.8-0.8-0.11.0-0.31.0-1.00.70.3-0.40.4-0.8-0.6-0.9-0.8-0.90.50.3-0.3
Pavlov. Cond. change in total contacts0.40.92.20.5-0.60.60.0-0.2-0.40.7-0.40.7-0.7-0.3-1.21.3-1.3-1.0-1.0-1.1-1.4-1.31.41.4-1.5
Pavlov. Cond. index score0.40.71.90.2-0.00.0-0.4-0.3-0.60.8-0.60.9-0.9-0.1-0.70.5-0.6-1.2-1.0-1.1-1.3-1.41.21.1-1.1
Pavlov. Cond. latency score0.30.61.50.2-0.20.2-0.2-0.2-0.50.7-0.50.7-0.7-0.1-0.70.7-0.7-1.0-0.9-0.9-1.1-1.21.11.0-1.1
Pavlov. Cond. lever contacts0.60.82.0-0.3-0.90.8-0.10.4-1.20.2-0.80.2-0.2-0.7-1.30.8-0.8-1.1-1.2-0.5-1.0-1.41.41.4-1.2
Pavlov. Cond. magazine entry number0.10.10.30.2-0.30.30.40.20.3-0.30.3-0.30.3-0.1-0.10.3-0.30.40.40.30.30.6-0.3-0.10.0
Pavlov. Cond. intertrial magazine entries0.20.41.10.60.9-0.8-0.7-0.60.81.1-0.11.0-1.00.61.0-0.00.0-0.50.2-1.0-0.6-0.2-0.20.10.0
Pavlov. Cond. lever-magazine prob. diff.0.40.61.70.1-0.10.0-0.4-0.2-0.60.7-0.60.7-0.7-0.1-0.60.5-0.5-1.0-0.9-0.9-1.2-1.31.11.0-1.0
Pavlov. Cond. response bias0.60.82.7-0.3-0.10.0-0.7-0.1-1.20.8-1.00.8-0.8-0.2-0.70.3-0.3-1.3-1.2-0.9-1.3-1.61.31.2-1.0
Time in closed arm before self-admin0.10.20.90.70.3-0.30.1-0.90.60.40.40.4-0.40.70.20.3-0.30.30.2-0.40.30.1-0.0-0.1-0.2
Time in closed arm after self-admin0.10.10.2-0.00.3-0.3-0.10.20.3-0.10.2-0.10.1-0.20.4-0.50.40.40.20.40.2-0.5-0.3-0.40.4
Time in open arm before self-admin1.01.23.30.30.5-0.5-0.9-0.9-0.41.4-0.71.5-1.50.7-0.30.4-0.4-1.8-1.1-1.6-1.7-1.51.31.1-1.3
Time in open arm after self-admin0.60.61.60.4-0.10.0-0.2-0.8-0.20.9-0.40.9-0.90.4-0.60.7-0.8-1.2-0.8-1.3-1.0-0.81.11.1-1.1
Bone: periosteal estimation1.22.79.62.70.9-0.81.2-2.63.1-0.22.6-0.10.12.41.30.7-0.71.82.4-0.11.11.3-1.8-1.80.2
Bone: periosteal perimeter0.71.34.51.81.2-1.1-0.0-2.12.00.51.50.5-0.52.01.30.2-0.10.81.3-0.60.20.2-1.1-1.10.2
Bone: post-yield work0.81.54.20.51.8-1.8-0.3-1.31.60.40.90.5-0.51.52.0-1.31.30.71.1-0.10.70.7-1.5-1.61.4
Progressive ratio test 1 active lever presses0.10.20.7-0.30.4-0.4-0.5-0.1-0.40.6-0.30.6-0.60.2-0.3-0.30.3-0.7-0.9-0.4-0.5-0.20.70.3-0.2
Progressive ratio test 1 breakpoint0.10.20.6-0.20.4-0.5-0.5-0.2-0.30.6-0.20.6-0.60.3-0.2-0.30.3-0.7-0.8-0.4-0.5-0.20.70.3-0.3
Progressive ratio test 1 inactive lever presses0.20.61.8-1.2-0.50.40.21.3-0.8-0.9-0.4-0.90.9-1.1-0.2-0.70.70.3-0.21.10.80.8-0.2-0.30.9
Progressive ratio test 2 active lever presses0.30.51.3-0.90.0-0.1-0.70.5-1.00.4-1.00.4-0.4-0.5-0.4-0.40.4-1.0-1.1-0.2-0.6-1.00.90.7-0.1
Progressive ratio test 2 breakpoint0.40.61.6-0.9-0.10.1-0.70.6-1.10.4-1.10.4-0.4-0.6-0.6-0.30.3-1.2-1.3-0.3-0.8-1.11.10.9-0.3
Progressive ratio test 2 inactive lever presses0.20.71.8-0.31.3-1.3-1.3-0.7-0.11.1-0.41.1-1.10.80.7-1.01.0-0.9-0.7-0.9-0.5-0.50.4-0.00.1
Incentive Sensitization - Responses0.10.41.5-0.40.2-0.2-0.70.0-0.60.6-0.90.6-0.6-0.10.1-0.20.2-1.0-0.7-0.6-0.7-1.20.60.7-0.3
Incentive Sensitization - Breakpoint0.20.41.4-0.60.1-0.1-0.70.3-0.80.5-1.00.5-0.5-0.40.0-0.30.3-1.0-0.8-0.4-0.6-1.20.60.7-0.1
Sum of active levers in priming session hrs 5-60.60.51.60.50.7-0.7-0.5-0.80.11.2-0.11.1-1.10.80.10.1-0.1-0.9-0.5-1.3-0.9-0.70.60.5-0.5
Progressive ratio1.54.310.41.6-2.52.63.20.51.7-2.62.3-2.82.8-0.5-1.52.4-2.32.42.32.11.92.1-1.3-0.9-0.3
Food seeking constrained by brief footshock0.30.31.10.0-0.60.60.1-0.2-0.4-0.1-0.3-0.00.00.0-1.00.7-0.7-0.7-0.7-0.2-0.5-1.00.90.8-0.9
Seeking ratio, punishment vs. effort1.43.26.5-0.71.9-1.9-2.5-1.0-1.22.4-1.72.5-2.51.00.7-1.21.2-2.4-2.0-2.2-1.9-2.21.51.2-0.6
Retroperitoneal fat weight0.31.23.2-1.4-0.40.40.21.2-0.7-1.4-0.1-1.51.5-0.90.2-1.21.21.30.41.81.10.8-0.9-1.01.5
Reaction time number correct0.31.23.3-0.1-1.81.81.80.6-0.0-1.50.4-1.51.5-0.8-1.41.1-1.10.60.31.11.10.90.00.1-0.2
Reaction time mean minus median0.31.84.1-0.32.0-2.0-2.0-0.2-0.42.0-0.92.0-2.00.31.5-1.31.3-1.1-0.8-1.6-1.7-0.90.40.20.1
Reaction time mean minus median AUC0.42.65.9-0.82.3-2.3-2.4-0.4-0.62.3-1.32.3-2.30.51.3-1.81.7-1.6-1.5-1.7-2.1-1.10.80.40.3
Reaction time num false alarms0.20.41.01.00.7-0.6-0.2-0.81.00.70.50.6-0.60.90.80.3-0.2-0.30.6-0.6-0.3-0.1-0.4-0.2-0.1
Reaction time num false alarms AUC0.30.62.61.60.5-0.40.0-1.21.40.70.80.7-0.71.10.70.8-0.8-0.20.9-0.9-0.4-0.1-0.5-0.2-0.5
Reaction time trials correct on left0.31.23.3-0.1-1.81.81.80.6-0.0-1.50.4-1.51.5-0.8-1.41.1-1.10.60.31.11.10.90.00.1-0.2
Reaction time trials on left0.31.13.2-0.1-1.81.81.80.5-0.0-1.40.4-1.41.4-0.7-1.41.1-1.10.60.31.01.00.90.00.1-0.2
Reaction time mean1.02.37.2-0.62.6-2.7-2.2-0.7-0.11.6-0.51.6-1.61.12.3-2.42.4-0.4-0.3-0.9-0.6-0.4-0.5-0.91.2
Reaction time mean AUC0.92.16.6-0.72.5-2.6-2.2-0.6-0.21.6-0.61.5-1.51.02.1-2.32.3-0.4-0.5-0.9-0.8-0.5-0.4-0.71.1
Median of all reaction times1.11.75.3-0.62.3-2.3-1.8-0.60.01.0-0.21.0-1.01.12.1-2.32.20.0-0.1-0.4-0.1-0.1-0.7-1.11.3
Reaction time omissions0.71.23.7-0.51.9-1.9-1.50.10.11.0-0.51.0-1.00.21.9-1.71.7-0.4-0.0-0.7-0.60.1-0.6-0.71.0
Reaction time false alarm rate1.01.42.71.61.6-1.5-1.1-1.51.31.60.51.6-1.61.51.40.1-0.1-0.60.5-1.6-1.1-0.8-0.3-0.1-0.5
Reaction time premature initiation rate0.10.20.70.0-0.00.00.6-0.10.4-0.50.4-0.50.50.10.1-0.10.10.50.40.40.80.5-0.4-0.50.2
Reaction time premature initiations0.31.02.90.2-1.11.21.70.30.6-1.40.8-1.41.4-0.4-0.80.7-0.61.00.71.21.41.1-0.5-0.50.1
Std. dev. reaction times0.72.46.00.52.5-2.5-2.1-1.30.32.4-0.42.4-2.41.41.8-1.11.1-1.1-0.6-2.0-1.8-0.90.20.0-0.2
Reaction time trials completed0.31.13.2-0.1-1.81.81.80.5-0.0-1.40.4-1.41.4-0.7-1.41.1-1.10.60.31.01.00.90.00.1-0.2
Reaction time trials AUC0.31.13.1-0.2-1.71.71.80.6-0.1-1.50.4-1.51.5-0.7-1.30.9-0.90.70.41.21.21.0-0.1-0.00.0
Run reversals in cocaine runway, females0.30.30.8-0.9-0.70.60.40.9-0.9-0.7-0.4-0.60.6-0.8-0.8-0.10.1-0.2-0.60.70.1-0.30.50.3-0.0
Run reversals in cocaine runway, males0.50.61.30.01.1-1.1-0.8-0.7-0.01.1-0.51.1-1.10.80.9-0.60.6-0.7-0.3-1.0-0.4-0.70.10.1-0.4
Latency to leave start box in cocaine runway0.70.92.7-0.41.6-1.6-1.3-0.60.20.7-0.20.7-0.71.01.7-1.61.60.00.1-0.30.1-0.5-0.7-0.81.3
Latency to leave start box in cocaine runway, F0.60.72.1-0.61.3-1.4-1.2-0.1-0.20.8-0.50.7-0.70.71.2-1.41.4-0.3-0.2-0.2-0.2-0.3-0.3-0.51.3
Latency to leave start box in cocaine runway, M0.40.31.00.10.6-0.6-0.3-0.50.7-0.20.4-0.20.20.41.0-0.60.60.80.70.20.6-0.3-0.9-0.90.8
Std. dev. time between licks in bursts1.32.56.91.72.6-2.5-1.1-2.11.81.80.91.8-1.82.12.6-0.80.8-0.11.0-1.6-0.5-0.6-1.1-1.10.5
Total sessions with >9 infusions0.60.72.00.3-0.20.2-0.20.2-0.40.8-0.20.8-0.8-0.3-1.20.8-0.9-1.0-1.1-0.9-1.3-0.61.41.2-1.4
Short access day 1 total inactive lever presses0.40.82.10.31.4-1.5-1.2-0.90.01.40.01.4-1.41.10.7-0.70.7-0.4-0.6-1.1-0.7-0.40.4-0.1-0.2
Short access day 10 total inactive lever presses0.10.62.3-0.50.6-0.6-0.50.4-0.0-0.2-0.2-0.20.20.01.5-1.11.10.20.80.61.10.9-1.3-0.91.1
Short access day 1 total infusions0.40.81.70.00.7-0.7-0.9-0.4-0.41.3-0.41.3-1.30.4-0.4-0.10.1-1.3-1.2-1.2-1.3-0.61.20.8-0.9
Short access day 10 total infusions0.40.61.8-0.8-0.10.1-0.61.1-1.10.5-0.90.5-0.5-1.0-0.8-0.20.1-1.1-1.3-0.4-0.9-0.61.21.0-0.4
Short access total infusions0.50.72.0-0.40.3-0.3-0.80.4-0.80.9-0.60.9-0.9-0.3-0.7-0.10.1-1.2-1.4-0.8-1.3-0.71.31.0-0.8
Short access day 1 locomotion0.30.51.0-0.70.8-0.8-1.00.7-0.50.8-0.80.8-0.8-0.40.6-0.90.9-0.6-0.6-0.6-0.8-0.10.20.20.3
Short access day 10 total locomotion0.52.06.22.40.3-0.21.5-1.32.5-0.22.4-0.20.21.50.71.2-1.21.42.2-0.11.21.7-1.5-1.4-0.2
Short access total locomotion0.20.31.20.80.7-0.60.2-0.30.90.30.90.3-0.30.60.5-0.00.00.50.6-0.20.21.1-0.6-0.70.2
One hour access (0.3 mA shock)0.70.82.3-1.20.4-0.5-1.30.8-1.10.7-1.50.7-0.7-0.80.4-1.01.0-1.2-1.0-0.6-0.6-1.40.50.60.1
Compulsive drug intake1.52.19.5-0.51.9-1.9-1.1-0.20.80.3-0.00.3-0.30.83.1-2.22.20.91.50.31.10.5-2.2-1.92.1
One hour access (shock baseline)0.51.44.0-0.8-1.00.9-0.20.9-1.50.2-1.10.2-0.2-1.3-1.90.7-0.7-1.4-1.8-0.5-1.1-1.72.01.8-1.2
Social response proportion0.60.82.51.40.6-0.50.3-1.11.6-0.11.5-0.20.21.30.80.2-0.21.11.30.00.71.0-1.1-1.10.3
Social responses0.50.62.51.60.00.00.4-0.71.5-0.11.4-0.20.20.80.30.8-0.80.91.2-0.00.20.9-0.8-0.7-0.2
Social time1.01.67.90.62.0-2.0-1.2-0.41.11.00.40.9-0.91.02.8-1.31.30.41.4-0.50.10.4-1.8-1.41.1
Soleus weight1.95.715.62.43.4-3.3-0.6-3.43.50.92.61.0-1.03.93.7-1.41.41.42.6-0.61.11.4-2.8-3.01.5
Bone: stiffness0.71.23.0-0.3-1.01.01.30.60.6-1.70.7-1.61.6-0.5-0.30.1-0.11.21.01.71.51.4-1.0-0.91.0
Tibialis anterior weight0.20.82.5-0.6-1.41.40.81.6-0.7-1.4-0.2-1.21.2-1.5-1.00.5-0.40.40.11.20.40.20.00.20.0
Time to tail flick, vehicle, before self-admin0.70.93.2-1.0-0.40.4-0.01.8-0.5-1.1-0.3-1.01.0-1.40.7-0.70.71.00.81.20.70.9-1.2-0.71.6
Time to tail flick, vehicle, after self-admin0.20.41.10.20.8-0.8-0.7-0.40.01.0-0.21.0-1.00.50.4-0.20.2-0.6-0.3-0.8-1.0-0.20.30.2-0.1
Time to tail flick, test, before self-admin0.30.30.90.0-0.91.00.30.6-0.5-0.1-0.5-0.10.1-0.9-0.70.9-0.9-0.3-0.2-0.0-0.1-0.60.50.8-0.7
Time to tail flick, test, after self-admin1.61.75.7-0.90.3-0.3-1.40.1-1.71.3-1.91.3-1.3-0.3-0.2-0.30.3-2.1-1.7-1.2-1.6-2.41.61.5-0.6
Delta time to tail flick, vehicle, before/after SA1.51.63.9-0.50.5-0.5-1.1-0.5-1.11.5-1.11.4-1.40.2-0.8-0.10.1-1.8-2.0-1.4-1.7-1.81.91.5-1.3
Delta time to tail flick, test, before/after SA0.50.62.1-1.50.4-0.5-0.90.7-1.2-0.0-1.10.0-0.0-0.50.4-1.41.4-0.6-0.80.3-0.4-0.70.20.00.9
Tibia length1.54.113.22.71.1-1.01.5-2.63.6-0.63.0-0.60.62.71.90.4-0.42.43.10.52.12.0-2.7-2.50.9
Ambulatory time before self-admin0.10.31.1-0.60.2-0.3-0.20.9-0.0-0.3-0.1-0.30.3-0.70.7-0.90.90.40.30.60.00.3-0.7-0.71.1
Ambulatory time after self-admin0.50.72.31.5-0.30.41.1-0.61.4-0.41.4-0.40.40.30.11.1-1.11.11.30.10.51.0-0.8-0.6-0.3
Bone: tissue strength0.10.10.3-0.30.1-0.10.30.2-0.1-0.40.3-0.30.3-0.0-0.0-0.40.40.30.10.60.50.5-0.2-0.50.4
Total heroin consumption0.00.10.20.30.2-0.1-0.00.10.40.20.20.1-0.1-0.10.50.0-0.00.20.4-0.1-0.00.3-0.4-0.20.2
Bone: trabecular number1.42.79.6-3.1-0.30.2-1.22.6-3.00.2-2.70.2-0.2-2.6-0.4-1.61.6-1.7-2.00.2-0.9-1.21.21.20.8
Bone: trabecular spacing1.92.78.83.00.10.01.3-2.82.7-0.52.8-0.40.42.70.11.6-1.61.92.0-0.01.01.4-1.2-1.2-0.6
Bone: trabecular thickness1.21.66.6-2.6-0.30.2-0.72.4-1.8-0.4-2.0-0.30.3-2.4-0.2-1.51.5-0.8-1.30.7-0.2-0.90.60.51.2
Bone: trabecular tissue density0.71.24.11.4-0.10.10.4-1.30.71.10.31.2-1.21.0-0.81.5-1.5-0.7-0.5-1.4-1.0-0.91.11.1-2.0
Water consumed over 24 hours0.10.20.70.50.7-0.6-0.3-0.70.70.20.40.2-0.20.80.7-0.20.20.30.5-0.20.20.1-0.5-0.50.0
Number of responses in last shaping day1.41.86.62.41.4-1.3-0.2-2.62.11.41.51.4-1.42.50.80.7-0.7-0.10.7-1.6-0.4-0.5-0.1-0.3-0.9