RT1-DMb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS NM_198740.2 0.04 0.03 8.9e-04 0.03 0.03 0.03 0.02 4.5e-04 3.7e-04 3.2e-04 1.3e-03
2 Adipose mRNA stability RT1-DMb 0.06 0.04 3.2e-05 0.02 0.05 0.03 0.04 4.3e-03 2.0e-06 1.0e-04 6.6e-05
3 Adipose isoform ratio NM_198740.2 0.07 0.05 7.7e-05 0.04 0.03 0.03 0.02 7.7e-05 2.4e-04 7.3e-04 1.6e-03
4 Adipose alternative TSS XM_063279017.1 0.04 0.02 1.6e-03 0.03 0.03 0.03 0.02 4.8e-04 4.5e-04 2.9e-04 1.2e-03
5 Adipose isoform ratio XM_063279017.1 0.07 0.05 5.3e-05 0.02 0.03 0.03 0.02 6.6e-03 1.3e-04 5.1e-04 9.1e-04
6 Liver mRNA stability RT1-DMb 0.06 0.04 1.6e-04 0.01 0.03 0.01 0.01 1.1e-02 6.3e-04 1.7e-02 1.3e-02
7 LHb gene expression RT1-DMb 0.6 0.13 5.8e-09 0.25 0.22 0.29 0.28 1.3e-06 4.7e-06 1.3e-07 2.8e-07
8 pVTA mRNA stability RT1-DMb 0.19 0.11 1.2e-05 0.07 0.05 0.04 0.06 2.3e-06 4.5e-05 1.5e-04 5.7e-06
9 BLA gene expression RT1-DMb 0.54 0.1 0.0e+00 0.5 0.51 0.52 0.53 6.0e-30 1.2e-30 3.8e-32 1.5e-32
10 OFC gene expression RT1-DMb 0.57 0.14 3.1e-10 0.33 0.36 0.3 0.37 1.2e-08 1.9e-09 5.4e-08 9.8e-10
11 Brain gene expression RT1-DMb 0.67 0.11 0.0e+00 0.42 0.46 0.49 0.5 8.6e-42 2.1e-47 3.1e-51 2.2e-52
12 NAcc gene expression RT1-DMb 0.45 0.09 0.0e+00 0.42 0.48 0.5 0.5 3.4e-70 5.2e-84 9.8e-88 1.8e-88
13 Brain mRNA stability RT1-DMb 0.05 0.04 7.1e-03 0 0.01 0 -0 3.4e-01 6.5e-02 2.7e-01 5.1e-01
14 IL gene expression RT1-DMb 0.46 0.14 7.9e-07 0.12 0.14 0.08 0.1 6.9e-04 3.6e-04 5.8e-03 2.1e-03
15 PL gene expression RT1-DMb 0.56 0.09 0.0e+00 0.44 0.42 0.46 0.46 5.7e-52 1.2e-49 6.4e-56 3.1e-55
16 pVTA gene expression RT1-DMb 0.56 0.1 0.0e+00 0.4 0.52 0.55 0.53 2.3e-34 1.7e-48 3.0e-52 3.0e-50
17 NAcc mRNA stability RT1-DMb 0.15 0.08 9.4e-13 0.07 0.09 0.08 0.09 1.6e-11 2.1e-13 4.3e-12 4.1e-13
18 IC gene expression RT1-DMb 0.45 0.13 2.4e-13 0.22 0.28 0.27 0.27 1.2e-09 2.5e-12 1.1e-11 6.8e-12
19 Adipose gene expression RT1-DMb 0.24 0.08 0.0e+00 0.14 0.18 0.16 0.17 2.7e-15 1.2e-19 9.9e-18 3.7e-18
20 Liver gene expression RT1-DMb 0.51 0.11 0.0e+00 0.24 0.43 0.42 0.42 3.2e-26 8.7e-52 2.6e-50 3.2e-50

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.81.66.4-1.92.5-1.11.8-1.01.81.61.8-1.1-0.9-0.9-0.70.8-0.01.10.7-0.0-0.6-0.0-0.1
Area under the delay curve0.20.21.20.4-1.10.6-0.40.1-1.10.50.40.3-0.1-0.00.1-0.5-0.3-0.20.6-0.2-0.00.1-0.4
BMI with tail1.55.48.92.10.02.5-2.02.92.6-2.1-2.12.72.62.42.5-0.33.0-2.4-2.32.72.62.41.8
BMI without tail0.52.97.92.5-2.22.8-2.22.70.2-1.6-1.91.71.61.21.1-2.01.3-1.4-1.01.11.30.90.1
Body weight2.410.515.33.9-2.93.6-3.73.80.2-3.9-3.83.93.73.53.3-1.13.0-3.8-3.12.83.32.52.1
Weight adjusted by age1.13.310.01.5-1.41.1-1.40.8-0.9-2.9-3.22.12.32.11.90.41.0-2.3-2.21.41.61.51.4
Bone surface0.00.10.30.30.1-0.5-0.5-0.1-0.10.10.4-0.2-0.3-0.0-0.1-0.1-0.10.10.1-0.3-0.2-0.50.1
Bone volume0.10.10.6-0.30.8-0.20.2-0.10.70.50.8-0.4-0.4-0.2-0.3-0.00.10.30.3-0.1-0.2-0.10.0
Breakpoint value in progressive ratio session0.20.30.9-0.2-0.0-0.80.1-0.3-0.30.80.4-0.6-0.9-0.5-0.6-0.2-0.50.70.4-0.7-0.6-0.8-0.5
Number of licking bursts0.20.51.6-0.2-0.6-1.00.3-0.5-1.10.20.2-0.7-0.9-0.6-0.6-0.0-0.80.40.6-1.0-0.6-1.3-0.2
Context. condit. distance diff. score2.53.110.7-2.92.0-3.32.7-2.5-0.11.91.9-1.9-1.3-1.3-1.12.3-0.90.80.4-0.8-0.8-0.90.6
Locomotion velocity, session 11.82.03.5-1.30.1-1.71.3-1.9-1.51.71.6-1.6-1.4-1.5-1.60.5-1.71.51.5-1.4-1.4-1.2-1.0
Locomotion distance, session 10.71.02.9-1.11.7-1.11.0-0.91.11.41.5-1.1-0.8-1.1-0.80.6-0.31.10.7-0.3-0.7-0.4-0.3
Locomotion velocity, session 20.50.61.2-0.40.0-0.80.4-0.5-0.41.01.0-0.8-1.1-0.8-0.9-0.2-0.80.80.8-0.9-0.8-1.0-0.5
Locomotion distance, session 20.50.73.4-1.11.9-1.20.9-0.91.20.30.3-0.4-0.0-0.10.11.50.40.0-0.40.60.30.50.8
Locomotion velocity, session 30.40.52.00.4-0.50.6-0.30.4-0.00.20.1-0.2-0.7-0.6-0.7-1.4-0.60.70.9-0.7-0.8-0.8-1.1
Locomotion distance, session 31.11.32.1-1.51.4-1.31.4-1.20.61.41.2-1.2-1.3-1.1-1.20.3-0.91.30.9-0.8-1.1-0.8-0.7
Stereotopy head waving bouts, day 30.81.03.21.7-1.80.6-1.60.7-1.4-1.5-1.41.00.70.80.7-0.50.1-1.0-0.5-0.00.5-0.10.4
Stereotopy head waving duration, day 30.60.84.01.4-2.00.7-1.20.5-1.7-1.2-1.20.60.30.30.2-0.8-0.3-0.50.1-0.30.1-0.2-0.2
Locomotion velocity, session 72.42.611.5-2.83.4-2.22.6-2.01.91.01.0-0.9-0.4-0.2-0.12.80.30.4-0.40.70.10.81.0
Locomotion distance, session 73.14.014.0-3.73.2-2.63.6-2.81.02.01.9-2.0-1.5-1.3-1.32.2-0.91.50.8-0.5-1.1-0.2-0.2
Stereotopy head waving bouts, day 72.12.44.70.6-2.00.5-0.40.1-1.90.70.3-1.2-1.6-1.7-1.9-2.0-1.81.51.9-1.9-1.6-1.8-2.2
Stereotopy head waving duration, day 70.91.13.61.3-1.90.9-1.10.6-1.4-0.2-0.5-0.3-0.7-0.8-0.9-1.7-0.90.61.0-1.1-0.8-1.1-1.3
Locomotion velocity, session 80.81.03.9-0.7-0.6-2.00.6-1.4-2.00.80.8-0.6-0.8-0.5-0.80.8-1.20.40.5-1.1-0.6-1.30.1
Locomotion distance, session 82.02.911.3-2.82.9-3.42.4-2.30.91.31.4-1.3-0.7-0.6-0.43.0-0.10.4-0.4-0.0-0.2-0.21.3
Degree of sensitization distance0.20.21.0-0.80.0-0.80.8-0.6-0.60.00.30.00.30.40.31.0-0.0-0.4-0.30.10.30.10.6
Degree of sensitization stereotypy2.73.05.5-0.1-1.1-0.10.3-0.4-1.41.61.2-1.9-2.1-2.3-2.4-1.8-2.02.12.2-2.1-2.0-2.0-2.3
Conditioned locomotion1.01.22.21.4-0.40.6-1.51.10.4-1.3-0.91.41.11.41.40.01.1-1.4-1.30.91.20.61.3
Cocaine response after cond. corrected1.11.73.5-0.31.5-0.50.20.21.6-1.2-1.10.91.21.51.41.71.6-1.3-1.71.51.41.21.9
Cocaine response after cond. not corrected0.50.81.70.9-0.50.1-0.90.7-0.1-1.3-1.30.90.91.21.00.40.8-1.1-1.20.61.00.31.1
Cocaine response before conditioning2.42.914.72.6-3.81.6-2.41.3-3.0-0.7-0.80.4-0.1-0.3-0.6-2.6-1.1-0.00.7-1.4-0.6-1.5-1.4
Saline control response1.31.88.82.1-1.83.0-1.92.0-0.0-1.1-1.01.00.90.50.4-2.20.6-0.50.10.50.50.7-0.7
Bone: connectivity density0.61.05.8-1.42.4-1.11.2-0.81.80.71.1-0.3-0.00.00.21.40.60.2-0.30.60.20.50.8
Bone: cortical apparent density0.91.44.41.4-0.22.1-1.41.81.4-1.1-1.01.11.11.11.1-0.91.3-0.8-0.91.11.01.00.3
Bone: cortical area0.10.20.80.7-0.90.6-0.70.6-0.4-0.1-0.00.3-0.1-0.1-0.1-0.8-0.1-0.20.0-0.20.0-0.3-0.2
Bone: cortical porosity4.24.68.3-0.4-1.9-0.20.6-1.1-2.82.11.7-2.0-2.3-2.4-2.6-1.8-2.82.22.9-2.5-2.4-2.2-2.8
Bone: cortical porosity3.53.89.2-0.3-1.9-0.50.5-1.3-3.01.81.4-1.8-2.0-2.2-2.3-1.3-2.61.82.6-2.3-2.1-2.0-2.3
Bone: cortical thickness0.30.52.90.7-0.31.7-0.61.41.10.50.40.2-0.1-0.3-0.1-1.60.40.30.30.1-0.1-0.0-0.8
Bone: cortical thickness1.01.24.71.5-0.32.2-1.52.11.6-0.6-0.51.10.80.60.7-1.61.1-0.4-0.30.80.60.6-0.1
Bone: cortical tissue density0.81.34.11.4-0.22.0-1.41.71.3-1.1-1.01.11.11.11.1-0.91.3-0.8-0.91.11.01.00.3
Condit. Reinf. active minus inactive responses1.01.11.7-1.00.0-0.71.0-1.3-1.01.21.2-1.2-0.8-1.2-1.10.1-1.31.21.3-1.0-1.2-0.7-1.1
Condit. Reinf. active-inactive response ratio0.20.20.60.3-0.70.8-0.30.3-0.50.10.1-0.00.1-0.3-0.2-0.8-0.40.30.5-0.3-0.4-0.2-0.7
Condit. Reinf. active responses0.40.61.4-1.20.9-0.71.1-1.1-0.01.01.1-0.8-0.2-0.6-0.50.7-0.60.70.5-0.3-0.6-0.0-0.4
Condit. Reinf. inactive responses0.81.05.1-1.72.3-1.01.5-1.11.51.21.3-0.8-0.3-0.5-0.31.10.10.70.10.2-0.30.40.0
Incentive salience index mean1.11.43.2-1.80.9-1.81.7-1.8-0.61.41.6-1.2-0.9-1.0-0.91.2-1.00.90.8-0.7-0.8-0.6-0.2
Condit. Reinf. lever presses1.32.07.7-2.52.1-2.82.3-2.00.41.21.3-1.0-0.6-0.4-0.22.4-0.20.3-0.3-0.1-0.1-0.21.0
Condit. Reinf. active minus inactive responses0.30.42.60.6-1.60.7-0.50.3-1.40.1-0.00.40.20.0-0.2-0.9-0.5-0.10.3-0.5-0.2-0.4-0.6
Condit. Reinf. active-inactive response ratio0.30.43.60.5-1.80.4-0.40.1-1.9-0.3-0.30.60.40.20.0-0.4-0.5-0.50.0-0.30.0-0.2-0.2
Condit. Reinf. active responses0.10.20.60.3-0.80.3-0.20.0-0.80.30.30.0-0.1-0.3-0.3-0.7-0.60.20.5-0.5-0.5-0.4-0.7
Condit. Reinf. inactive responses0.10.10.50.60.20.6-0.60.60.70.20.30.0-0.1-0.2-0.0-0.70.20.30.30.0-0.1-0.1-0.4
Condit. Reinf. lever presses1.11.62.9-1.40.1-0.61.5-1.2-0.81.71.5-1.4-1.2-1.6-1.6-0.3-1.51.31.4-1.2-1.4-1.0-1.3
Condit. Reinf. lever reinforcers received0.30.41.10.0-0.90.10.0-0.2-1.10.70.6-0.3-0.4-0.6-0.7-0.8-0.90.60.8-0.8-0.8-0.8-0.9
Conditioned reinforcement - actives0.00.10.4-0.40.6-0.10.3-0.30.4-0.0-0.1-0.10.10.1-0.00.50.2-0.1-0.40.40.20.60.2
Conditioned reinforcement - inactives0.00.10.30.00.30.1-0.0-0.4-0.1-0.5-0.30.20.10.0-0.00.60.00.0-0.30.40.10.6-0.0
Conditioned locomotion0.20.30.9-0.80.5-0.70.8-0.9-0.2-0.3-0.30.00.40.30.11.00.0-0.4-0.60.50.20.70.5
Patch foraging indifference point 0 sec0.51.54.11.6-1.52.0-1.51.8-0.0-1.4-1.61.31.31.10.9-1.30.8-0.6-0.50.80.70.9-0.3
Patch foraging indifference point AUC0.30.72.30.2-1.5-0.0-0.00.3-1.40.40.4-0.3-0.6-0.7-0.8-1.4-0.90.61.0-1.1-0.8-1.2-1.0
Delay disc. indifference point, 0s delay0.20.20.60.1-0.1-0.2-0.3-0.3-0.5-0.1-0.30.50.30.70.50.80.2-0.5-0.20.30.50.40.6
Delay disc. indifference point, 16s delay0.10.10.50.1-0.30.60.00.1-0.10.50.4-0.1-0.3-0.4-0.2-0.7-0.20.10.6-0.1-0.20.1-0.5
Delay disc. indifference point, 2s delay0.40.44.30.1-1.5-0.10.0-0.4-2.10.30.10.20.00.10.10.1-0.7-0.30.4-0.4-0.0-0.1-0.2
Delay disc. indifference point, 24s delay0.20.42.40.6-1.40.8-0.5-0.1-1.5-0.3-0.2-0.10.1-0.4-0.3-0.7-0.7-0.00.5-0.3-0.30.1-0.7
Delay disc. indifference point, 4s delay0.60.73.91.3-2.00.9-1.20.9-1.40.0-0.20.60.20.40.2-1.1-0.2-0.40.3-0.30.1-0.2-0.5
Delay disc. indifference point, 8s delay0.10.10.50.0-0.50.4-0.1-0.2-0.70.60.60.2-0.0-0.10.0-0.1-0.3-0.20.6-0.00.00.3-0.2
Indifference point function ln k0.10.41.00.1-0.3-0.5-0.2-0.6-0.80.40.6-0.7-0.8-0.7-0.7-0.1-0.90.70.6-0.9-0.7-1.0-0.5
Indifference point function log k0.10.41.00.1-0.3-0.5-0.2-0.6-0.80.40.6-0.7-0.8-0.7-0.7-0.1-0.90.70.6-0.9-0.7-1.0-0.5
Patch foraging total patch changes 0 sec0.51.54.41.6-1.52.1-1.51.80.0-1.3-1.61.31.31.10.8-1.40.8-0.6-0.40.80.70.9-0.4
Patch foraging total patch changes 12 sec0.60.82.41.3-1.41.4-1.21.5-0.2-1.1-1.20.70.70.50.5-1.60.3-0.4-0.10.20.20.2-0.6
Patch foraging total patch changes 18 sec0.61.53.51.00.21.8-0.91.91.9-1.2-1.71.01.41.01.0-0.91.6-0.7-0.61.31.01.30.3
Patch foraging total patch changes 24 sec0.10.32.0-0.61.00.50.60.31.40.40.2-0.10.20.0-0.0-0.20.50.30.30.50.10.8-0.3
Patch foraging total patch changes 6 sec0.40.73.30.8-1.01.8-0.61.40.2-0.5-0.50.81.00.60.6-1.10.7-0.4-0.00.70.60.9-0.4
Patch foraging time to switch 0 sec0.93.67.80.81.71.1-0.91.22.8-1.8-1.71.51.81.92.21.22.5-2.0-2.32.32.12.22.1
Patch foraging water rate 0 sec0.10.31.00.2-0.80.5-0.00.4-0.5-0.6-0.71.01.00.90.60.10.4-0.5-0.20.50.60.60.4
Patch foraging water rate 12 sec0.10.20.6-0.40.50.20.50.30.80.60.7-0.3-0.2-0.4-0.4-0.5-0.00.80.7-0.2-0.3-0.2-0.6
Patch foraging water rate 18 sec0.10.30.80.5-0.40.8-0.30.70.3-0.4-0.30.90.60.60.5-0.40.5-0.4-0.10.50.50.50.2
Patch foraging water rate 24 sec0.10.10.50.5-0.10.6-0.50.70.50.10.00.20.10.00.0-0.50.30.20.10.10.0-0.0-0.3
Patch foraging water rate 6 sec0.10.20.60.4-0.00.6-0.30.80.6-0.2-0.30.70.50.40.4-0.50.5-0.1-0.10.30.30.20.0
Seeking ratio, delayed vs. immediate footshock1.42.09.41.8-2.51.4-1.71.9-1.10.30.4-0.2-0.6-0.8-0.7-3.1-0.70.61.1-1.3-0.9-1.7-1.7
Distance traveled before self-admin0.51.02.00.70.30.1-0.90.91.0-1.1-1.31.11.21.21.20.51.3-1.1-1.41.01.10.51.4
Distance traveled after self-admin0.71.13.51.9-1.81.1-1.91.8-0.5-1.2-1.10.90.50.60.5-1.60.4-0.8-0.5-0.00.4-0.40.0
Extensor digitorum longus weight0.10.20.9-0.80.0-0.70.9-0.4-0.3-0.10.10.30.20.30.30.70.2-0.7-0.50.30.50.30.9
Bone: elastic displacement0.40.61.2-0.9-0.20.31.0-0.5-0.41.00.8-0.7-0.6-0.9-0.9-0.4-0.70.91.0-0.5-0.7-0.1-1.1
Bone: elastic work0.00.10.3-0.1-0.60.50.20.2-0.30.30.10.0-0.0-0.1-0.1-0.3-0.00.10.10.10.10.2-0.3
Bone: endosteal estimation1.12.78.32.0-2.90.2-1.90.8-2.6-2.4-2.41.71.31.61.2-0.00.3-2.1-1.40.31.20.11.2
Bone: endosteal perimeter0.40.92.90.9-1.3-0.9-1.0-0.2-1.7-1.2-1.10.90.60.90.60.80.0-1.3-1.0-0.00.7-0.31.2
Epididymis fat weight2.09.932.62.31.84.1-2.34.25.7-2.1-2.23.03.22.83.2-1.04.3-2.2-2.73.93.03.71.5
Delta time in closed arm before/after self-admin0.90.81.70.6-0.10.4-0.80.50.2-0.8-0.81.31.21.31.30.70.9-1.1-1.11.01.10.90.9
Delta time in open arm before/after self-admin0.10.10.3-0.10.20.10.1-0.10.10.10.1-0.6-0.4-0.5-0.5-0.3-0.30.20.3-0.3-0.4-0.1-0.5
Diff in mean of infusions in LGA sessions0.40.83.8-1.22.0-1.41.1-1.01.20.70.6-0.6-0.6-0.20.01.40.20.2-0.20.1-0.00.10.7
Delay discount exponential model param0.20.31.7-0.51.3-0.50.5-0.11.3-0.6-0.5-0.10.20.20.10.60.50.1-0.80.40.20.10.6
Extinction: sum of active levers before priming0.10.21.4-0.20.1-1.20.1-0.6-0.4-0.1-0.2-0.0-0.10.20.30.8-0.10.1-0.6-0.10.1-0.10.4
Active lever presses in extinction session 60.30.31.1-1.01.0-0.30.9-0.80.50.80.20.10.2-0.00.11.00.2-0.00.00.60.20.90.2
Bone: final force2.13.45.51.9-0.82.2-1.82.31.1-2.0-2.02.32.12.12.1-0.52.1-1.9-1.91.92.01.71.3
Bone: final moment1.52.43.81.4-0.71.9-1.31.80.9-1.8-1.81.91.81.81.7-0.31.7-1.7-1.61.61.71.51.1
Food consumed during 24 hour testing period1.02.03.40.9-0.10.4-0.91.00.5-1.7-1.81.51.51.71.70.81.6-1.8-1.91.41.71.21.8
Glucose1.01.67.8-1.2-0.5-2.51.1-2.4-2.8-0.6-0.5-0.4-0.1-0.1-0.32.3-1.2-0.5-0.3-0.6-0.2-0.40.8
Heart weight0.60.96.11.2-2.51.3-1.00.5-2.2-0.4-0.41.00.60.40.3-0.9-0.4-0.80.3-0.10.30.2-0.3
Delay discount hyperbolic model param0.40.52.3-0.41.5-0.50.4-0.11.5-0.7-0.6-0.10.30.30.30.80.70.0-0.90.60.30.20.7
Intermittent access intake day 1-15 change0.10.41.10.8-0.80.4-0.80.5-0.40.40.4-0.5-0.3-0.7-0.5-1.0-0.40.50.8-0.6-0.4-0.7-0.6
Intermittent access intake escalation0.10.72.70.8-1.00.8-0.80.7-0.20.60.5-0.6-0.4-0.9-0.7-1.6-0.50.81.1-0.6-0.7-0.7-1.1
Intermittent access intake escalation 20.30.40.90.2-0.7-0.3-0.2-0.1-0.80.60.6-0.7-0.7-0.9-0.7-0.8-0.70.61.0-0.7-0.7-0.8-0.7
Intermitt. access day 1 inactive lever presses0.00.41.30.9-0.3-0.9-0.90.3-0.4-1.1-0.60.7-0.10.60.60.70.3-0.4-0.80.00.4-0.40.7
Intermitt. access day 15 inactive lever presses0.10.51.81.0-0.60.3-1.00.5-0.2-1.4-1.30.80.60.50.60.10.4-0.5-0.80.40.60.40.4
Intermitt. access escalation Index0.20.71.8-0.91.2-1.30.7-0.40.71.31.3-0.7-1.1-0.5-0.50.5-0.10.80.4-0.6-0.4-0.90.1
Intermittent access day 1 total infusions0.61.96.6-2.61.9-1.82.5-2.5-0.00.71.0-1.4-0.5-0.9-0.92.1-0.70.60.30.1-0.50.70.0
Intermittent access day 15 total infusions0.20.61.4-1.00.5-0.31.1-0.9-0.10.91.0-1.2-0.5-1.1-1.00.2-0.70.90.8-0.3-0.70.0-0.7
Intermittent access terminal intake (last 3 days)0.30.51.2-1.00.1-0.41.0-1.0-0.60.70.7-1.1-0.4-0.9-1.00.2-0.80.70.7-0.3-0.60.1-0.7
Intermittent access total infusions0.60.72.3-1.40.8-0.61.5-1.4-0.30.60.8-1.1-0.4-0.8-0.90.8-0.70.60.6-0.2-0.60.3-0.5
Intermittent access day 1 locomotion0.30.51.6-1.11.2-0.51.0-0.80.7-0.1-0.1-0.10.50.30.21.20.3-0.2-0.70.70.30.90.5
Intermittent access day 15 total locomotion0.20.61.50.6-0.60.8-0.60.70.1-0.9-0.90.81.20.80.9-0.20.7-1.0-1.00.90.80.90.6
Intermittent access total locomotion0.10.10.6-0.30.20.40.3-0.10.3-0.3-0.30.10.70.30.30.10.2-0.4-0.50.60.30.80.2
Intermittent access standard deviation0.31.54.32.1-1.11.8-2.01.60.2-1.3-1.01.41.41.11.0-0.90.9-0.8-0.50.90.90.90.2
Left kidney weight0.86.516.03.5-2.84.0-3.33.90.4-2.4-2.32.92.42.42.2-2.42.2-2.4-1.81.72.21.50.8
Right kidney weight1.28.114.83.8-2.33.8-3.73.80.8-3.1-3.13.33.03.02.8-1.72.7-3.0-2.52.32.71.91.5
Cocaine induced anxiety0.00.10.30.40.1-0.3-0.50.50.4-0.4-0.10.3-0.00.50.40.10.4-0.3-0.50.10.3-0.30.6
Post-drug Anxiety0.20.20.70.7-0.40.5-0.70.80.1-0.1-0.20.70.20.70.5-0.40.4-0.4-0.40.10.3-0.20.3
Baseline Anxiety0.10.10.40.3-0.50.7-0.20.2-0.30.2-0.00.30.60.30.3-0.10.1-0.30.00.20.30.40.1
Tail length0.63.422.52.4-4.71.5-2.11.3-3.9-1.6-1.70.90.60.40.1-2.1-0.9-0.8-0.1-0.90.1-1.0-0.6
Length with tail1.35.719.03.1-4.42.0-2.92.0-3.1-3.4-3.32.52.32.21.8-1.10.7-2.6-1.90.71.70.61.0
Length without tail2.111.119.33.0-1.72.2-3.02.70.2-4.4-4.14.13.94.24.00.83.2-4.3-3.83.23.82.93.3
Times rat made contact with spout1.11.33.1-0.70.20.40.8-0.30.21.41.3-1.2-1.3-1.4-1.4-1.2-1.01.61.8-0.9-1.3-0.7-1.7
Lifetime Intake0.40.51.8-1.30.7-0.51.3-1.3-0.30.20.4-0.8-0.2-0.5-0.60.9-0.50.40.20.0-0.30.5-0.3
Liver weight, left1.11.85.21.5-1.60.2-1.40.9-1.1-2.1-2.31.51.41.61.40.20.7-1.7-1.60.51.20.21.3
Liver weight, right0.61.13.40.9-1.7-0.4-0.90.1-1.8-1.3-1.01.20.91.31.00.60.2-1.3-1.10.30.90.11.1
Locomotor activity0.91.56.81.5-2.60.6-1.31.3-1.8-0.2-0.50.1-0.5-0.4-0.5-2.2-0.90.40.6-1.3-0.7-1.7-1.2
Locomotor testing distance0.30.62.31.3-1.50.1-1.21.1-0.8-0.8-1.10.30.10.20.1-1.2-0.2-0.2-0.4-0.6-0.1-1.0-0.3
Locomotor testing rearing0.31.23.21.5-1.00.3-1.61.2-0.2-1.6-1.81.31.21.21.1-0.20.8-1.2-1.40.60.90.20.8
Locomotion in novel chamber0.10.10.40.2-0.00.2-0.20.50.40.20.60.2-0.20.20.1-0.60.20.00.3-0.00.0-0.0-0.1
Locomotion in novel chamber post-restriction0.41.22.20.9-0.61.3-0.91.30.5-1.0-1.01.51.51.41.3-0.41.1-1.2-1.21.11.11.10.8
Fecal boli incidents, locomotor time 10.30.72.7-1.01.6-1.10.9-0.90.9-0.4-0.5-0.20.10.30.31.60.5-0.3-1.00.70.40.90.8
Change in fecal boli incidents, locomotor task0.80.82.81.3-1.70.5-1.30.8-1.3-1.0-0.91.00.81.00.9-0.30.2-0.8-0.60.10.6-0.20.5
Time >=10cm from walls, locomotor time 12.83.56.62.0-1.01.2-2.22.00.3-2.0-2.32.31.92.52.60.21.9-2.0-2.31.52.01.11.9
Bouts of movement, locomotor time 10.60.82.3-0.30.1-0.10.2-0.1-0.11.41.5-1.0-1.2-1.1-1.2-0.7-0.71.01.0-1.0-1.0-1.2-0.9
Total resting periods, locomotor time 10.50.61.6-0.30.1-0.30.3-0.3-0.21.11.3-1.0-1.0-0.9-1.1-0.4-0.70.80.8-0.9-0.8-1.0-0.6
Rest time, locomotor task time 10.20.30.9-0.2-0.3-0.50.1-0.5-0.70.30.2-0.7-0.9-0.4-0.7-0.2-0.70.50.5-0.7-0.7-0.7-0.6
Distance moved, locomotor task time 10.20.72.00.7-0.61.0-0.60.80.2-0.9-0.91.11.40.71.1-0.10.8-0.9-0.70.80.90.80.7
Vertical activity count, locomotor time 10.31.93.91.1-0.41.8-1.01.50.7-1.4-1.51.92.01.41.9-0.11.5-1.5-1.31.31.41.40.9
Time >=10cm from walls, locomotor time 21.13.07.51.6-1.31.0-1.60.9-0.9-2.5-2.71.82.12.32.20.61.2-2.0-2.01.31.71.41.6
Bouts of movement, locomotor time 20.31.12.10.6-1.30.4-0.50.3-1.21.01.4-0.7-0.9-1.0-1.0-1.4-1.11.01.0-1.4-1.1-1.4-1.4
Total resting periods, locomotor time 20.52.03.80.3-1.50.0-0.2-0.1-1.71.51.7-1.2-1.4-1.4-1.5-1.5-1.61.41.4-2.0-1.5-1.9-1.8
Rest time, locomotor task time 20.10.10.80.00.2-0.9-0.2-0.1-0.10.30.30.0-0.40.20.20.60.1-0.2-0.3-0.20.2-0.50.6
Distance moved, locomotor task time 21.52.05.10.40.21.4-0.20.50.8-1.7-1.71.52.31.41.70.71.4-1.6-1.31.91.52.11.3
Vertical activity count, locomotor time 20.92.04.80.5-0.11.2-0.40.50.4-1.8-1.81.62.21.61.90.71.3-1.8-1.51.71.52.01.3
Light reinforcement 10.73.26.31.90.21.4-1.91.91.7-2.5-2.51.62.12.12.00.12.1-1.6-1.81.71.81.21.7
Light reinforcement 21.02.34.21.20.30.4-1.31.01.1-2.1-2.11.41.71.81.81.01.8-1.4-1.91.71.81.41.8
Bone: marrow area1.22.98.72.1-3.00.3-2.10.9-2.5-2.5-2.51.81.51.71.4-0.10.4-2.2-1.50.41.40.21.3
Bone: maximum diameter0.20.42.50.2-0.8-1.1-0.3-0.8-1.6-0.00.2-0.1-0.3-0.2-0.20.5-0.7-0.30.1-0.6-0.2-0.70.3
Bone: maximum force0.91.82.81.3-0.61.4-1.31.50.7-1.5-1.51.71.51.61.5-0.21.5-1.5-1.51.41.51.31.0
Bone: maximum moment0.61.21.80.9-0.51.1-0.81.00.3-1.3-1.31.31.21.31.20.11.1-1.3-1.21.11.21.10.9
Mean time between licks in bursts0.21.23.9-0.6-0.3-2.00.4-1.4-1.70.80.8-1.0-1.2-0.7-1.00.5-1.40.60.7-1.5-1.1-1.6-0.3
Mean num. licks in bursts0.10.31.5-0.00.51.20.00.41.10.50.50.10.1-0.2-0.2-0.70.20.50.50.4-0.10.7-0.7
Cd content in liver2.93.26.8-0.52.2-0.30.4-0.42.0-1.4-1.21.42.11.81.92.62.0-1.7-1.92.41.92.62.2
Co content in liver2.32.74.21.50.11.5-1.51.31.2-1.8-1.72.02.11.81.90.41.8-1.8-1.71.91.81.91.4
Cu content in liver0.70.92.5-1.00.90.31.0-0.11.01.61.6-0.8-0.8-1.0-0.9-0.8-0.41.21.3-0.5-0.9-0.4-1.1
Fe content in liver0.50.61.30.40.30.9-0.40.81.2-0.8-0.80.80.80.80.8-0.11.0-0.7-0.71.00.81.00.5
K content in liver0.50.51.2-1.01.1-0.90.9-0.70.61.01.0-0.7-0.9-0.7-0.60.4-0.30.50.4-0.3-0.4-0.40.0
Mg content in liver0.80.82.9-1.00.5-1.70.8-1.0-0.41.41.6-0.8-0.9-0.8-0.60.7-0.60.60.5-0.8-0.6-1.10.2
Mn content in liver0.50.52.6-0.50.2-1.60.3-0.8-0.6-0.5-0.20.20.20.60.51.50.1-0.8-0.80.10.5-0.11.3
Na content in liver0.70.82.3-0.1-0.40.40.30.40.01.10.8-0.7-1.1-1.0-1.0-1.5-0.71.11.2-1.0-1.0-1.2-1.3
Rb content in liver0.60.62.2-1.11.3-0.71.0-0.60.8-0.00.10.20.50.60.71.50.7-0.5-0.70.80.60.91.0
Se content in liver1.61.85.6-0.5-1.1-1.50.5-1.3-2.41.21.2-1.2-1.4-1.3-1.4-0.0-1.81.01.3-1.8-1.3-1.9-0.9
Sr content in liver0.60.51.3-0.10.2-0.40.2-0.4-0.2-0.9-0.90.70.80.70.61.20.5-0.9-0.70.80.81.01.0
Zn content in liver0.50.51.70.10.5-0.6-0.2-0.60.0-0.9-0.70.70.80.70.81.30.5-0.9-0.80.70.70.81.2
Bone: minimum diameter0.30.71.80.5-1.2-0.4-0.60.1-1.3-0.8-0.81.00.70.80.70.60.2-1.3-1.00.20.80.01.1
Time in familiar zone, hab. session 11.51.62.8-1.61.5-0.31.7-1.00.91.61.6-1.4-1.3-1.6-1.4-0.4-0.91.51.4-0.7-1.3-0.3-1.4
Time in novel zone, hab. session 11.31.53.51.9-1.70.5-1.91.0-1.1-1.7-1.71.31.21.41.20.00.6-1.3-1.00.51.00.20.9
Total zone transitions, hab. session 10.40.61.3-0.70.6-0.80.6-0.40.31.10.9-1.0-0.9-1.0-0.8-0.0-0.51.00.6-0.7-0.7-1.0-0.5
Total locomotion distance, hab. session 10.40.51.5-1.01.0-0.90.8-0.40.71.11.2-0.8-0.8-0.7-0.60.2-0.20.80.3-0.5-0.5-0.7-0.2
Locomotion velocity, hab. session 10.40.51.6-0.80.6-0.70.7-0.30.31.11.3-0.8-0.8-0.8-0.7-0.1-0.40.80.5-0.6-0.6-0.8-0.4
Time in familiar zone, hab. session 20.50.52.90.8-0.20.9-0.81.20.80.50.4-0.0-0.4-0.4-0.2-1.7-0.00.60.4-0.5-0.6-0.8-0.9
Time in novel zone, hab. session 20.30.31.0-0.1-0.3-0.10.2-0.7-0.9-0.8-0.80.20.60.40.31.00.0-0.5-0.10.50.50.90.5
Total zone transitions, hab. session 20.20.21.80.10.8-0.1-0.20.71.40.30.40.20.10.20.3-0.10.7-0.2-0.40.20.3-0.20.5
Total locomotion distance, hab. session 20.50.63.7-0.81.8-0.90.60.11.90.91.1-0.3-0.3-0.00.10.50.60.3-0.20.20.1-0.20.6
Locomotion velocity, hab. session 20.60.83.6-1.11.9-1.20.9-0.31.71.11.3-0.6-0.6-0.2-0.20.70.30.5-0.0-0.1-0.2-0.50.5
Novel to familiar place preference ratio0.20.30.7-0.70.1-0.40.8-0.8-0.60.40.2-0.8-0.5-0.5-0.60.3-0.60.60.7-0.3-0.4-0.1-0.4
Novelty place preference0.30.30.9-0.5-0.3-0.30.6-0.7-0.90.40.2-0.8-0.5-0.5-0.70.1-0.70.60.9-0.5-0.5-0.3-0.6
Time in novel zone, NPP test0.30.41.3-0.4-0.6-0.20.6-0.7-1.10.50.4-0.8-0.5-0.6-0.7-0.1-0.90.71.0-0.6-0.6-0.4-0.7
Total zone transitions, NPP test0.81.24.1-1.62.0-1.81.4-1.31.01.41.4-1.1-0.8-0.9-0.71.4-0.20.70.3-0.1-0.4-0.30.3
Total locomotion distance, NPP test1.21.77.8-2.02.8-1.61.8-1.21.91.01.2-0.40.00.00.22.20.8-0.0-0.40.90.50.91.2
Locomotion velocity, NPP test1.52.110.4-2.23.2-1.92.0-1.32.31.01.2-0.7-0.2-0.10.12.40.80.1-0.50.90.40.81.3
Intraocular pressure0.20.31.6-0.41.3-0.10.4-0.21.3-0.3-0.50.00.20.20.20.40.4-0.2-0.50.60.20.70.4
Delta distance traveled before/after self-admin1.21.35.61.1-2.41.1-0.80.6-2.0-0.10.1-0.3-0.6-0.7-0.8-2.0-1.10.31.1-1.1-0.8-0.9-1.4
Delta ambulatory time before/after self-admin0.71.25.71.2-2.41.1-1.00.8-2.0-0.10.0-0.2-0.5-0.5-0.7-1.9-1.00.21.0-1.1-0.7-1.0-1.3
Parametrial fat weight2.14.99.11.60.62.5-1.52.63.0-2.0-1.72.52.32.42.5-0.13.0-2.0-2.22.72.52.32.0
Pavlov. Cond. lever latency4.45.511.33.1-0.83.4-3.03.21.9-2.7-2.62.72.42.32.3-1.52.4-2.1-1.92.12.01.91.0
Pavlov. Cond. magazine entry latency3.84.86.9-1.8-0.7-1.91.9-2.0-2.32.62.4-2.6-2.5-2.5-2.6-0.4-2.62.22.4-2.5-2.3-2.4-1.8
Pavlov. Cond. change in total contacts1.81.93.7-1.1-0.8-1.11.2-1.3-1.91.61.5-1.5-1.4-1.4-1.5-0.2-1.81.31.4-1.6-1.4-1.5-1.2
Pavlov. Cond. index score4.15.27.7-2.70.1-2.82.7-2.7-2.12.82.7-2.6-2.5-2.4-2.40.7-2.52.02.0-2.2-2.0-2.1-1.2
Pavlov. Cond. latency score4.35.48.2-2.70.1-2.92.7-2.7-2.22.92.8-2.6-2.5-2.4-2.40.7-2.62.12.1-2.3-2.1-2.2-1.3
Pavlov. Cond. lever contacts2.83.39.2-2.81.0-3.02.7-2.7-1.32.02.0-2.0-1.6-1.5-1.51.9-1.61.31.0-1.2-1.1-1.1-0.1
Pavlov. Cond. magazine entry number2.63.44.71.60.41.6-1.61.71.9-2.1-2.02.22.22.12.10.32.2-1.8-1.92.11.92.01.5
Pavlov. Cond. intertrial magazine entries1.21.43.90.11.60.6-0.20.32.0-1.1-0.90.91.41.11.31.01.5-0.8-1.11.71.11.80.9
Pavlov. Cond. lever-magazine prob. diff.4.15.17.5-2.70.2-2.72.7-2.7-2.02.72.6-2.7-2.5-2.4-2.40.8-2.42.02.0-2.2-2.0-2.0-1.2
Pavlov. Cond. response bias2.83.55.3-2.20.1-2.32.2-2.2-1.82.12.1-2.3-2.1-2.1-2.00.5-2.11.61.6-1.9-1.7-1.8-1.0
Pavlov. Cond. lever latency0.70.91.71.0-0.1-0.1-1.30.50.1-1.3-1.11.00.81.31.30.80.9-1.1-1.20.81.00.51.3
Pavlov. Cond. magazine entry latency0.30.51.7-1.20.2-0.91.3-1.1-0.70.70.6-0.6-0.3-0.5-0.60.7-0.60.30.5-0.3-0.3-0.1-0.1
Pavlov. Cond. change in total contacts0.51.12.2-0.6-0.70.10.8-0.5-1.01.41.2-0.9-0.9-1.3-1.3-1.0-1.31.21.4-1.1-1.2-0.9-1.5
Pavlov. Cond. index score0.50.91.8-1.2-0.1-0.41.3-0.9-0.81.31.1-0.9-0.7-1.1-1.2-0.3-1.10.91.1-0.8-0.9-0.6-0.9
Pavlov. Cond. latency score0.40.71.2-0.9-0.3-0.21.1-0.7-0.71.11.0-0.8-0.6-1.0-1.0-0.4-0.90.81.0-0.7-0.8-0.5-0.9
Pavlov. Cond. lever contacts0.40.71.3-0.80.10.21.0-0.4-0.11.10.8-0.9-0.6-1.1-1.1-0.7-0.80.91.1-0.6-0.9-0.4-1.1
Pavlov. Cond. magazine entry number0.10.10.90.8-0.30.4-0.90.50.1-0.4-0.40.2-0.10.20.2-0.50.1-0.0-0.1-0.10.0-0.2-0.1
Pavlov. Cond. intertrial magazine entries0.40.82.80.4-0.5-0.8-0.7-0.3-0.90.60.6-0.9-1.2-0.9-0.9-0.6-1.10.90.7-1.4-1.1-1.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.50.71.6-1.1-0.1-0.31.3-0.8-0.61.21.0-0.8-0.6-1.0-1.0-0.3-0.90.81.0-0.7-0.8-0.5-0.8
Pavlov. Cond. response bias0.71.02.5-1.40.2-0.51.6-0.9-0.41.31.1-1.1-0.9-1.2-1.3-0.2-1.01.01.1-0.8-1.0-0.6-1.0
Time in closed arm before self-admin0.00.10.60.1-0.6-0.40.0-0.2-0.7-0.4-0.1-0.0-0.10.0-0.2-0.2-0.3-0.10.0-0.3-0.1-0.2-0.0
Time in closed arm after self-admin0.10.10.4-0.10.0-0.30.0-0.1-0.0-0.1-0.20.60.20.60.40.50.3-0.5-0.50.50.40.50.3
Time in open arm before self-admin1.21.42.3-1.1-0.2-0.81.2-1.2-1.21.00.8-1.4-1.2-1.4-1.4-0.2-1.51.51.5-1.2-1.3-1.2-1.2
Time in open arm after self-admin0.80.91.6-0.6-0.3-0.50.8-0.7-0.90.80.8-1.2-1.0-1.3-1.2-0.5-1.11.01.3-1.1-1.0-0.8-1.0
Bone: periosteal estimation0.71.66.31.8-2.50.7-1.81.1-1.8-1.6-1.51.30.81.00.8-0.70.2-1.5-0.90.00.8-0.20.6
Bone: periosteal perimeter0.20.42.60.9-1.6-0.0-0.90.2-1.6-0.5-0.50.50.10.20.1-0.3-0.3-0.5-0.2-0.40.1-0.60.1
Bone: post-yield work0.40.71.80.3-0.1-0.8-0.4-0.3-0.5-1.2-1.10.60.70.90.81.30.5-1.1-1.20.50.80.41.3
Progressive ratio test 1 active lever presses0.20.41.8-0.80.7-0.70.7-1.2-0.2-0.8-0.4-0.20.40.20.21.3-0.1-0.2-0.70.50.20.90.5
Progressive ratio test 1 breakpoint0.20.41.7-0.70.6-0.70.7-1.1-0.3-0.8-0.4-0.20.40.20.21.3-0.1-0.2-0.60.50.20.80.5
Progressive ratio test 1 inactive lever presses0.30.82.10.51.20.2-0.60.21.4-1.1-0.50.80.70.81.00.81.0-0.6-1.21.10.81.10.8
Progressive ratio test 2 active lever presses0.30.41.0-0.91.0-0.60.9-0.90.30.30.6-0.8-0.6-0.6-0.60.6-0.30.40.2-0.1-0.40.1-0.2
Progressive ratio test 2 breakpoint0.30.41.0-0.91.0-0.70.9-1.00.30.40.7-0.9-0.7-0.8-0.80.5-0.40.50.4-0.1-0.50.0-0.3
Progressive ratio test 2 inactive lever presses0.20.52.8-0.90.9-1.20.8-1.6-0.5-0.30.1-0.4-0.2-0.2-0.11.7-0.30.1-0.30.2-0.00.40.5
Incentive Sensitization - Responses0.30.91.8-0.70.3-0.70.7-0.5-0.11.11.3-1.1-1.4-1.3-1.3-0.4-0.80.91.1-0.9-1.0-1.0-0.9
Incentive Sensitization - Breakpoint0.40.81.7-0.70.5-0.60.6-0.40.21.11.2-1.1-1.3-1.2-1.3-0.3-0.70.91.1-0.8-0.9-0.9-0.8
Sum of active levers in priming session hrs 5-60.40.41.2-0.6-0.2-0.60.6-0.9-1.10.50.2-0.7-0.6-0.7-0.60.3-0.90.60.2-0.7-0.7-0.5-0.5
Progressive ratio1.33.811.23.2-2.43.2-3.03.40.4-1.3-1.52.11.71.51.5-2.51.4-1.3-0.80.91.20.6-0.0
Food seeking constrained by brief footshock0.10.10.3-0.2-0.00.20.3-0.3-0.2-0.1-0.5-0.2-0.1-0.2-0.2-0.2-0.30.20.1-0.0-0.30.2-0.6
Seeking ratio, punishment vs. effort1.22.78.0-2.31.3-2.62.2-2.8-1.01.01.0-2.1-1.6-1.5-1.61.6-1.71.41.0-1.1-1.5-0.8-0.6
Retroperitoneal fat weight0.31.53.50.11.10.6-0.10.71.9-0.8-0.61.31.21.31.30.91.7-1.1-1.41.71.41.61.4
Reaction time number correct0.31.03.01.7-0.41.7-1.71.40.9-1.2-1.21.10.80.70.8-0.90.8-0.3-0.30.70.50.6-0.0
Reaction time mean minus median0.31.95.3-2.20.8-2.32.2-1.9-0.91.71.7-1.4-1.1-1.1-1.11.2-1.10.80.7-1.0-0.9-0.9-0.1
Reaction time mean minus median AUC0.42.57.8-2.81.5-2.62.7-2.7-0.81.51.4-1.6-0.9-1.0-1.02.3-1.10.70.4-0.6-0.7-0.20.3
Reaction time num false alarms0.30.41.70.4-1.0-0.0-0.40.2-1.00.50.3-0.2-0.7-0.4-0.6-0.8-0.70.40.3-1.0-0.7-1.3-0.6
Reaction time num false alarms AUC0.41.03.10.8-1.70.2-0.80.5-1.50.60.4-0.3-1.0-0.6-0.9-1.5-1.00.60.7-1.4-0.9-1.8-1.0
Reaction time trials correct on left0.31.03.01.7-0.41.7-1.71.40.9-1.2-1.21.10.80.70.8-0.90.8-0.3-0.30.70.50.6-0.0
Reaction time trials on left0.31.02.91.7-0.41.6-1.61.30.8-1.2-1.21.00.80.70.8-0.90.8-0.3-0.30.70.50.6-0.0
Reaction time mean0.71.56.4-2.11.4-2.32.0-1.9-0.30.50.6-0.6-0.0-0.00.12.5-0.1-0.3-0.70.20.30.41.2
Reaction time mean AUC0.61.46.4-2.11.4-2.22.0-1.9-0.30.50.5-0.6-0.0-0.00.12.5-0.1-0.3-0.60.20.20.41.1
Median of all reaction times0.81.26.0-1.61.3-1.81.4-1.4-0.00.00.2-0.10.40.40.52.50.3-0.7-1.00.60.70.81.5
Reaction time omissions0.40.73.3-1.50.9-1.81.4-1.1-0.10.80.7-0.7-0.4-0.3-0.21.4-0.20.1-0.2-0.3-0.1-0.30.6
Reaction time false alarm rate1.11.54.0-0.4-1.4-0.80.4-0.5-2.01.41.2-0.9-1.4-1.1-1.3-0.8-1.50.81.0-1.8-1.3-2.0-1.0
Reaction time premature initiation rate0.20.41.10.20.0-0.0-0.20.30.3-1.0-0.80.60.80.80.60.30.6-0.6-0.70.70.70.70.7
Reaction time premature initiations0.41.33.01.4-0.41.1-1.41.20.7-1.7-1.51.21.31.31.1-0.41.1-0.9-1.01.11.01.00.7
Std. dev. reaction times0.61.95.3-2.10.2-2.32.0-2.1-1.61.51.4-1.4-1.1-1.1-1.11.3-1.40.70.6-1.2-0.9-1.0-0.1
Reaction time trials completed0.31.02.91.7-0.41.6-1.61.30.8-1.2-1.21.00.80.70.8-0.90.8-0.3-0.30.70.50.6-0.0
Reaction time trials AUC0.31.12.91.7-0.21.6-1.71.31.0-1.3-1.21.10.90.80.9-0.70.9-0.4-0.50.90.70.70.2
Run reversals in cocaine runway, females0.40.41.3-0.50.80.50.5-0.10.9-0.8-0.30.40.60.60.60.60.6-0.6-0.50.90.61.20.5
Run reversals in cocaine runway, males0.40.52.0-0.80.3-1.40.8-0.9-0.50.20.4-1.0-0.7-0.7-0.60.4-0.70.40.5-0.7-0.6-0.7-0.2
Latency to leave start box in cocaine runway0.30.41.8-0.90.7-1.30.9-0.8-0.10.30.1-0.0-0.20.30.21.30.1-0.3-0.40.20.30.20.8
Latency to leave start box in cocaine runway, F0.40.52.3-1.01.0-1.40.9-1.00.10.1-0.3-0.1-0.00.40.21.50.0-0.2-0.60.20.20.20.6
Latency to leave start box in cocaine runway, M0.10.10.30.1-0.1-0.1-0.10.20.00.20.30.30.00.30.30.10.4-0.5-0.10.30.40.20.5
Std. dev. time between licks in bursts0.50.94.5-0.5-1.2-1.50.5-0.9-2.10.71.0-0.3-0.7-0.4-0.60.1-1.20.00.4-1.3-0.6-1.50.0
Total sessions with >9 infusions0.20.30.9-0.8-0.1-0.30.8-1.0-0.9-0.1-0.2-0.6-0.3-0.4-0.60.3-0.80.50.1-0.3-0.60.1-0.7
Short access day 1 total inactive lever presses0.30.62.9-1.10.4-1.21.1-1.5-1.1-0.4-0.5-0.0-0.10.20.01.7-0.5-0.1-0.70.1-0.00.40.4
Short access day 10 total inactive lever presses0.00.20.90.80.4-0.3-0.90.80.8-0.20.30.1-0.60.00.2-0.20.40.3-0.3-0.4-0.1-0.8-0.0
Short access day 1 total infusions0.30.62.8-1.40.5-1.21.3-1.7-0.9-0.0-0.1-0.8-0.3-0.3-0.51.3-0.70.50.1-0.1-0.40.3-0.1
Short access day 10 total infusions0.20.41.0-1.01.0-0.60.9-1.00.10.10.4-0.7-0.1-0.4-0.51.0-0.30.6-0.10.1-0.30.4-0.3
Short access total infusions0.40.52.3-1.40.8-0.91.3-1.5-0.5-0.1-0.1-0.60.0-0.2-0.31.4-0.50.3-0.20.2-0.20.7-0.1
Short access day 1 locomotion0.30.41.6-1.10.9-1.20.9-0.90.10.30.5-0.8-0.6-0.4-0.50.8-0.40.6-0.1-0.4-0.4-0.40.0
Short access day 10 total locomotion0.41.55.52.0-2.30.7-2.01.3-1.5-1.6-1.70.91.01.00.8-1.20.1-1.0-1.1-0.10.5-0.50.3
Short access total locomotion0.30.41.50.2-0.4-0.4-0.3-0.1-0.6-1.2-1.00.50.80.80.70.60.2-0.7-1.20.30.50.30.6
One hour access (0.3 mA shock)1.11.32.7-1.51.2-1.31.5-0.90.51.31.7-1.5-1.5-1.4-1.30.1-0.71.11.1-0.8-1.0-0.9-0.6
Compulsive drug intake0.20.21.2-0.20.5-1.10.00.30.60.10.2-0.2-0.7-0.00.30.30.4-0.3-0.2-0.30.2-0.90.9
One hour access (shock baseline)0.20.61.9-1.30.7-0.21.4-1.00.10.91.1-0.8-0.3-0.8-1.00.2-0.60.80.8-0.0-0.60.4-0.8
Social response proportion0.50.61.51.0-1.20.3-1.00.5-0.9-1.0-0.91.10.60.90.90.10.3-0.8-0.70.30.70.30.4
Social responses0.50.62.91.3-1.70.6-1.31.0-1.0-0.5-0.70.70.00.40.2-1.1-0.1-0.3-0.2-0.40.0-0.6-0.3
Social time0.30.42.90.1-0.5-1.4-0.30.2-0.60.50.4-0.3-0.8-0.2-0.2-0.2-0.40.3-0.0-1.1-0.5-1.70.0
Soleus weight0.61.85.01.1-1.5-1.1-1.2-0.3-2.2-1.9-1.41.20.91.51.21.40.2-1.9-1.50.21.10.01.8
Bone: stiffness0.81.42.31.2-0.01.3-1.21.51.2-1.4-1.31.31.31.41.3-0.31.4-1.2-1.21.21.21.00.9
Tibialis anterior weight0.10.31.30.10.21.1-0.01.01.2-0.0-0.00.50.10.30.3-1.00.6-0.2-0.10.40.30.3-0.0
Time to tail flick, vehicle, before self-admin0.30.42.40.60.50.4-0.81.31.50.60.50.3-0.10.30.4-0.80.70.1-0.60.00.2-0.50.3
Time to tail flick, vehicle, after self-admin0.10.20.6-0.70.0-0.60.6-0.8-0.70.3-0.4-0.6-0.5-0.4-0.60.4-0.60.30.1-0.5-0.5-0.5-0.2
Time to tail flick, test, before self-admin0.91.13.10.3-0.50.2-0.20.60.11.51.5-0.7-1.0-1.1-1.1-1.7-0.71.21.1-1.1-1.1-1.4-1.3
Time to tail flick, test, after self-admin2.62.85.1-1.60.8-1.01.6-1.3-0.12.12.0-2.0-2.3-2.1-2.2-0.3-1.52.11.8-1.5-1.8-1.5-1.5
Delta time to tail flick, vehicle, before/after SA1.11.24.4-1.90.9-1.02.0-2.1-0.70.60.3-1.2-0.6-1.0-1.01.3-1.00.80.8-0.3-0.70.3-0.5
Delta time to tail flick, test, before/after SA0.40.42.3-1.11.5-0.51.0-0.71.00.40.4-0.3-0.3-0.1-0.01.20.30.1-0.00.50.20.60.5
Tibia length0.92.47.62.7-2.60.9-2.81.7-1.5-2.0-1.81.51.11.31.2-0.80.6-1.5-1.30.11.1-0.30.8
Ambulatory time before self-admin0.00.20.5-0.10.5-0.4-0.00.20.7-0.3-0.40.20.40.30.40.30.5-0.3-0.50.40.40.10.6
Ambulatory time after self-admin0.40.72.81.4-1.70.7-1.41.2-0.8-0.8-0.60.50.20.20.1-1.30.0-0.4-0.0-0.30.1-0.6-0.2
Bone: tissue strength0.60.61.6-0.20.40.10.2-0.10.3-0.8-0.90.60.90.90.91.10.8-0.8-1.01.10.91.20.9
Total heroin consumption0.20.20.70.7-0.5-0.0-0.70.4-0.20.50.4-0.2-0.6-0.4-0.3-0.6-0.30.50.5-0.6-0.4-0.9-0.4
Bone: trabecular number1.01.88.8-2.23.0-1.32.1-1.22.21.51.7-1.1-0.8-0.8-0.61.10.01.30.60.1-0.60.1-0.1
Bone: trabecular spacing1.31.98.12.0-2.91.5-1.81.3-2.0-1.8-2.01.01.00.90.8-0.90.2-1.3-0.80.20.80.20.2
Bone: trabecular thickness0.71.05.9-1.32.4-0.71.1-0.62.21.11.4-0.3-0.4-0.3-0.10.80.50.30.10.50.00.50.4
Bone: trabecular tissue density0.71.13.40.0-1.40.00.2-0.6-1.80.30.1-1.0-1.0-1.1-1.3-1.0-1.50.91.3-1.3-1.2-1.1-1.4
Water consumed over 24 hours0.00.00.20.1-0.4-0.2-0.1-0.0-0.5-0.0-0.0-0.1-0.20.0-0.00.0-0.1-0.20.1-0.20.1-0.20.2
Number of responses in last shaping day0.50.76.9-0.0-1.7-0.70.2-0.8-2.6-0.7-0.6-0.2-0.10.1-0.40.0-1.0-0.30.0-0.6-0.3-0.5-0.1