Hub : Genes

RT1-DMb

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS NM_198740.2 0.04 0.03 8.9e-04 0.03 0.03 0.03 0.02 4.5e-04 3.7e-04 3.2e-04 1.2e-03
2 Adipose mRNA stability RT1-DMb 0.06 0.04 3.2e-05 0.02 0.05 0.03 0.04 4.3e-03 2.0e-06 1.0e-04 6.3e-05
3 Adipose isoform ratio NM_198740.2 0.07 0.05 7.7e-05 0.04 0.03 0.03 0.02 7.7e-05 2.4e-04 7.3e-04 1.6e-03
4 Adipose alternative TSS XM_063279017.1 0.04 0.02 1.6e-03 0.03 0.03 0.03 0.02 4.8e-04 4.5e-04 2.9e-04 1.3e-03
5 Adipose isoform ratio XM_063279017.1 0.07 0.05 5.3e-05 0.02 0.03 0.03 0.02 6.6e-03 1.3e-04 5.1e-04 8.9e-04
6 Liver mRNA stability RT1-DMb 0.06 0.04 1.6e-04 0.01 0.03 0.01 0.01 1.1e-02 6.3e-04 1.7e-02 1.4e-02
7 LHb gene expression RT1-DMb 0.6 0.13 5.8e-09 0.25 0.22 0.29 0.28 1.3e-06 4.7e-06 1.3e-07 2.4e-07
8 pVTA mRNA stability RT1-DMb 0.19 0.11 1.2e-05 0.07 0.05 0.04 0.07 2.3e-06 4.5e-05 1.8e-04 5.4e-06
9 BLA gene expression RT1-DMb 0.54 0.1 0.0e+00 0.5 0.51 0.52 0.53 6.0e-30 1.2e-30 3.8e-32 1.5e-32
10 OFC gene expression RT1-DMb 0.57 0.14 3.1e-10 0.33 0.36 0.3 0.37 1.2e-08 1.9e-09 5.3e-08 1.0e-09
11 Brain gene expression RT1-DMb 0.67 0.11 0.0e+00 0.42 0.46 0.49 0.49 8.6e-42 2.1e-47 3.1e-51 2.3e-52
12 NAcc gene expression RT1-DMb 0.45 0.09 0.0e+00 0.42 0.48 0.5 0.5 3.4e-70 5.2e-84 9.7e-88 1.8e-88
13 Brain mRNA stability RT1-DMb 0.05 0.04 7.1e-03 0 0.01 0 -0 3.4e-01 6.5e-02 2.7e-01 5.5e-01
14 IL gene expression RT1-DMb 0.46 0.14 7.9e-07 0.12 0.14 0.08 0.1 6.9e-04 3.6e-04 5.8e-03 2.2e-03
15 PL gene expression RT1-DMb 0.56 0.09 0.0e+00 0.44 0.42 0.46 0.46 5.7e-52 1.2e-49 6.5e-56 3.5e-55
16 pVTA gene expression RT1-DMb 0.56 0.1 0.0e+00 0.4 0.52 0.55 0.53 2.3e-34 1.7e-48 3.0e-52 3.1e-50
17 NAcc mRNA stability RT1-DMb 0.15 0.08 9.4e-13 0.07 0.09 0.08 0.09 1.6e-11 2.1e-13 4.3e-12 4.7e-13
18 IC gene expression RT1-DMb 0.45 0.13 2.4e-13 0.22 0.28 0.27 0.27 1.2e-09 2.5e-12 1.1e-11 6.4e-12
19 Adipose gene expression RT1-DMb 0.24 0.08 0.0e+00 0.14 0.18 0.16 0.17 2.7e-15 1.2e-19 9.9e-18 3.9e-18
20 Liver gene expression RT1-DMb 0.51 0.11 0.0e+00 0.24 0.43 0.42 0.42 3.2e-26 8.7e-52 2.7e-50 3.4e-50

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.91.66.41.92.51.1-1.8-1.01.8-1.6-1.8-1.2-0.9-0.9-0.70.8-0.0-1.1-0.7-0.0-0.6-0.0-0.1
Area under the delay curve0.20.21.2-0.4-1.1-0.60.40.1-1.1-0.5-0.40.3-0.1-0.00.1-0.5-0.30.2-0.6-0.2-0.00.1-0.4
BMI with tail1.65.48.9-2.10.0-2.52.12.92.62.12.12.72.62.42.5-0.33.02.42.32.72.62.41.8
BMI without tail1.02.97.9-2.5-2.2-2.82.22.70.21.61.91.81.61.21.1-2.01.31.41.01.11.30.90.1
Body weight2.410.515.3-3.9-2.9-3.63.73.80.23.93.83.93.73.53.3-1.13.03.83.12.83.32.52.1
Weight adjusted by age2.23.310.0-1.5-1.4-1.11.40.8-0.92.93.22.12.22.11.90.41.02.32.21.41.61.51.4
Bone surface0.00.10.3-0.30.10.50.5-0.1-0.1-0.1-0.4-0.2-0.3-0.0-0.1-0.1-0.1-0.1-0.1-0.3-0.2-0.50.1
Bone volume0.10.10.60.30.80.2-0.2-0.10.7-0.5-0.8-0.4-0.4-0.2-0.3-0.00.1-0.3-0.3-0.1-0.2-0.10.0
Breakpoint value in progressive ratio session0.30.30.90.2-0.00.8-0.1-0.3-0.3-0.8-0.4-0.6-0.9-0.5-0.6-0.2-0.5-0.7-0.4-0.7-0.6-0.8-0.5
Number of licking bursts0.30.51.60.2-0.61.0-0.3-0.5-1.1-0.2-0.2-0.7-0.9-0.6-0.6-0.0-0.8-0.4-0.6-1.0-0.6-1.3-0.2
Context. condit. distance diff. score2.53.110.72.92.03.3-2.7-2.5-0.1-1.9-1.9-1.9-1.3-1.3-1.12.3-0.9-0.8-0.4-0.8-0.8-0.90.6
Locomotion velocity, session 11.92.03.51.30.11.7-1.3-1.9-1.5-1.7-1.6-1.6-1.4-1.5-1.60.5-1.7-1.5-1.5-1.4-1.4-1.2-1.0
Locomotion distance, session 10.81.02.91.11.71.1-1.0-0.91.1-1.4-1.5-1.1-0.8-1.1-0.80.6-0.3-1.1-0.7-0.3-0.7-0.4-0.3
Locomotion velocity, session 20.50.61.20.40.00.8-0.4-0.5-0.4-1.0-1.0-0.8-1.1-0.8-0.9-0.2-0.8-0.8-0.8-0.9-0.8-1.0-0.5
Locomotion distance, session 20.50.73.41.11.91.2-0.9-0.91.2-0.3-0.3-0.4-0.0-0.10.11.50.4-0.00.40.60.30.50.8
Locomotion velocity, session 30.40.52.0-0.4-0.5-0.60.30.4-0.0-0.2-0.1-0.2-0.7-0.6-0.7-1.4-0.6-0.7-0.9-0.7-0.8-0.8-1.1
Locomotion distance, session 31.21.32.11.51.41.3-1.4-1.20.6-1.4-1.2-1.2-1.3-1.1-1.20.3-0.9-1.3-0.9-0.8-1.1-0.8-0.7
Stereotopy head waving bouts, day 30.91.03.2-1.7-1.8-0.61.60.7-1.41.51.41.00.60.80.7-0.50.11.00.5-0.00.5-0.10.4
Stereotopy head waving duration, day 30.70.84.0-1.4-2.0-0.71.20.5-1.71.21.20.60.30.30.2-0.8-0.30.5-0.1-0.30.1-0.2-0.2
Locomotion velocity, session 72.42.611.52.83.42.2-2.6-2.01.9-1.0-1.0-0.9-0.4-0.2-0.12.80.3-0.40.40.70.10.81.0
Locomotion distance, session 73.24.014.03.73.22.6-3.6-2.81.0-2.0-1.9-2.0-1.5-1.3-1.32.2-0.9-1.5-0.8-0.5-1.1-0.2-0.2
Stereotopy head waving bouts, day 72.12.44.7-0.6-2.0-0.50.40.1-1.9-0.7-0.3-1.2-1.6-1.7-1.9-2.0-1.8-1.5-1.9-1.9-1.6-1.8-2.2
Stereotopy head waving duration, day 70.91.13.6-1.3-1.9-0.91.10.6-1.40.20.5-0.3-0.7-0.8-0.9-1.7-0.9-0.6-1.0-1.1-0.8-1.1-1.3
Locomotion velocity, session 80.81.03.90.7-0.62.0-0.6-1.4-2.0-0.8-0.8-0.6-0.8-0.5-0.70.8-1.2-0.4-0.5-1.1-0.6-1.30.1
Locomotion distance, session 82.02.911.32.82.93.4-2.4-2.30.9-1.3-1.4-1.3-0.7-0.6-0.43.0-0.1-0.40.4-0.0-0.2-0.21.3
Degree of sensitization distance0.20.21.00.80.00.8-0.8-0.6-0.6-0.0-0.30.00.30.40.31.0-0.00.40.30.10.30.10.6
Degree of sensitization stereotypy2.83.05.50.1-1.10.1-0.3-0.4-1.4-1.6-1.2-1.9-2.1-2.3-2.3-1.8-2.0-2.1-2.2-2.1-2.0-2.0-2.3
Conditioned locomotion1.11.22.2-1.4-0.4-0.61.51.10.41.30.91.41.11.41.40.01.11.41.30.91.20.61.3
Cocaine response after cond. corrected1.41.73.50.31.50.5-0.20.21.61.21.10.91.21.51.41.71.61.31.71.51.41.21.9
Cocaine response after cond. not corrected0.70.81.7-0.9-0.5-0.10.80.7-0.11.31.30.90.91.21.00.40.81.11.20.61.00.31.1
Cocaine response before conditioning2.42.914.7-2.6-3.8-1.62.41.3-3.00.70.80.4-0.1-0.3-0.5-2.6-1.10.0-0.7-1.4-0.6-1.5-1.4
Saline control response1.31.88.8-2.1-1.8-3.01.92.0-0.01.11.01.00.90.50.4-2.20.60.5-0.10.50.50.7-0.7
Bone: connectivity density0.61.05.81.42.41.1-1.2-0.81.8-0.7-1.1-0.3-0.10.00.21.40.6-0.20.30.60.20.50.8
Bone: cortical apparent density1.01.44.4-1.4-0.2-2.11.41.81.41.11.01.11.11.11.1-0.91.30.80.91.11.01.00.3
Bone: cortical area0.10.20.8-0.7-0.9-0.60.70.6-0.40.10.00.3-0.1-0.1-0.1-0.8-0.10.2-0.0-0.20.0-0.3-0.2
Bone: cortical porosity4.24.68.30.4-1.90.2-0.6-1.1-2.8-2.1-1.7-2.0-2.3-2.4-2.6-1.8-2.8-2.2-2.9-2.5-2.4-2.2-2.8
Bone: cortical porosity3.53.89.20.3-1.90.5-0.5-1.3-3.0-1.8-1.4-1.8-2.0-2.2-2.3-1.3-2.6-1.8-2.6-2.3-2.1-2.0-2.3
Bone: cortical thickness0.30.52.9-0.7-0.3-1.70.61.41.1-0.5-0.40.2-0.1-0.3-0.1-1.60.4-0.3-0.30.1-0.1-0.0-0.8
Bone: cortical thickness1.01.24.7-1.5-0.3-2.21.52.11.60.60.51.10.80.60.7-1.61.10.40.30.80.60.6-0.1
Bone: cortical tissue density1.01.34.1-1.4-0.2-2.01.41.71.31.11.01.11.11.11.1-0.91.30.80.91.11.01.00.3
Condit. Reinf. active minus inactive responses1.01.11.71.00.00.7-1.0-1.3-1.0-1.2-1.2-1.2-0.8-1.2-1.10.1-1.3-1.2-1.3-1.0-1.2-0.7-1.1
Condit. Reinf. active-inactive response ratio0.20.20.6-0.3-0.7-0.80.30.3-0.5-0.1-0.1-0.00.1-0.3-0.2-0.8-0.4-0.3-0.5-0.3-0.4-0.2-0.7
Condit. Reinf. active responses0.40.61.41.20.90.7-1.1-1.1-0.0-1.0-1.1-0.8-0.2-0.6-0.50.7-0.6-0.7-0.5-0.3-0.6-0.0-0.4
Condit. Reinf. inactive responses0.81.05.11.72.31.0-1.5-1.11.5-1.2-1.3-0.8-0.3-0.5-0.31.10.1-0.7-0.10.2-0.30.40.0
Incentive salience index mean1.11.43.21.80.91.8-1.7-1.8-0.6-1.4-1.6-1.2-0.9-1.0-0.91.2-1.0-0.9-0.8-0.7-0.8-0.6-0.2
Condit. Reinf. lever presses1.42.07.72.52.12.8-2.3-2.00.4-1.2-1.3-1.0-0.6-0.4-0.22.4-0.2-0.30.3-0.1-0.1-0.21.0
Condit. Reinf. active minus inactive responses0.30.42.6-0.6-1.6-0.70.50.3-1.4-0.10.00.40.20.0-0.1-0.9-0.50.1-0.3-0.5-0.2-0.4-0.6
Condit. Reinf. active-inactive response ratio0.40.43.6-0.5-1.8-0.40.40.1-1.90.30.30.60.40.20.0-0.4-0.50.5-0.0-0.30.0-0.2-0.2
Condit. Reinf. active responses0.10.20.6-0.3-0.8-0.30.20.0-0.8-0.3-0.30.0-0.1-0.3-0.3-0.7-0.6-0.2-0.5-0.5-0.5-0.4-0.7
Condit. Reinf. inactive responses0.10.10.5-0.60.2-0.60.60.60.7-0.2-0.30.0-0.1-0.2-0.0-0.70.2-0.3-0.30.0-0.1-0.1-0.4
Condit. Reinf. lever presses1.21.62.91.40.10.6-1.5-1.2-0.8-1.7-1.5-1.4-1.2-1.6-1.6-0.3-1.5-1.3-1.4-1.2-1.4-1.0-1.3
Condit. Reinf. lever reinforcers received0.30.41.1-0.0-0.9-0.1-0.0-0.2-1.1-0.7-0.6-0.3-0.4-0.6-0.7-0.8-0.9-0.6-0.8-0.8-0.8-0.8-0.9
Conditioned reinforcement - actives0.10.10.40.40.60.1-0.3-0.30.40.00.1-0.10.10.1-0.00.50.20.10.40.40.20.60.2
Conditioned reinforcement - inactives0.10.10.3-0.00.3-0.10.0-0.4-0.10.50.30.20.20.0-0.00.60.0-0.00.30.40.10.6-0.0
Conditioned locomotion0.20.30.90.80.50.7-0.8-0.9-0.20.30.30.00.40.30.11.00.00.40.60.50.20.70.5
Patch foraging indifference point 0 sec0.81.54.1-1.6-1.5-2.01.51.8-0.01.41.61.31.31.10.9-1.30.80.60.50.80.70.9-0.3
Patch foraging indifference point AUC0.50.72.3-0.2-1.50.00.00.3-1.4-0.4-0.4-0.3-0.6-0.7-0.8-1.4-0.9-0.6-1.0-1.1-0.8-1.2-1.0
Delay disc. indifference point, 0s delay0.20.20.6-0.1-0.10.20.3-0.3-0.50.10.30.50.30.70.50.80.20.50.20.30.50.40.6
Delay disc. indifference point, 16s delay0.10.10.5-0.1-0.3-0.6-0.00.1-0.1-0.5-0.4-0.1-0.3-0.4-0.2-0.7-0.2-0.1-0.6-0.1-0.20.1-0.5
Delay disc. indifference point, 2s delay0.40.44.3-0.1-1.50.1-0.0-0.4-2.1-0.3-0.10.20.00.10.10.1-0.70.3-0.4-0.4-0.0-0.1-0.2
Delay disc. indifference point, 24s delay0.40.42.4-0.6-1.4-0.80.5-0.1-1.50.30.2-0.10.1-0.4-0.3-0.7-0.70.0-0.5-0.3-0.30.1-0.7
Delay disc. indifference point, 4s delay0.60.73.9-1.3-2.0-0.91.20.9-1.4-0.00.20.60.20.40.2-1.1-0.20.4-0.3-0.30.1-0.2-0.5
Delay disc. indifference point, 8s delay0.10.10.5-0.0-0.5-0.40.1-0.2-0.7-0.6-0.60.2-0.0-0.10.0-0.1-0.30.2-0.6-0.00.00.3-0.2
Indifference point function ln k0.20.41.0-0.1-0.30.50.1-0.6-0.8-0.4-0.6-0.7-0.9-0.7-0.7-0.1-0.9-0.7-0.6-0.9-0.7-1.0-0.5
Indifference point function log k0.20.41.0-0.1-0.30.50.1-0.6-0.8-0.4-0.6-0.7-0.9-0.7-0.7-0.1-0.9-0.7-0.6-0.9-0.7-1.0-0.5
Patch foraging total patch changes 0 sec0.81.54.4-1.6-1.5-2.11.51.80.01.31.61.31.31.10.8-1.40.80.60.40.80.70.9-0.4
Patch foraging total patch changes 12 sec0.60.82.4-1.3-1.4-1.41.21.5-0.21.11.20.70.70.50.5-1.60.30.40.10.20.20.2-0.6
Patch foraging total patch changes 18 sec1.01.53.5-1.00.2-1.80.91.91.91.21.71.01.41.01.0-0.91.60.70.61.31.01.30.3
Patch foraging total patch changes 24 sec0.20.32.00.61.0-0.5-0.60.31.4-0.4-0.2-0.10.30.0-0.0-0.20.5-0.3-0.30.50.10.8-0.3
Patch foraging total patch changes 6 sec0.50.73.3-0.8-1.0-1.80.61.40.20.50.50.81.00.60.6-1.10.70.40.00.70.60.9-0.4
Patch foraging time to switch 0 sec1.73.67.8-0.81.7-1.10.91.22.81.81.71.51.81.92.21.22.52.02.32.32.12.22.1
Patch foraging water rate 0 sec0.20.31.0-0.2-0.8-0.50.00.4-0.50.60.71.01.00.90.60.10.40.50.20.50.60.60.4
Patch foraging water rate 12 sec0.10.20.60.40.5-0.2-0.50.30.8-0.6-0.7-0.3-0.2-0.4-0.4-0.5-0.0-0.8-0.7-0.2-0.3-0.2-0.6
Patch foraging water rate 18 sec0.20.30.8-0.5-0.4-0.80.30.70.30.40.30.90.60.60.5-0.40.50.40.10.50.50.50.2
Patch foraging water rate 24 sec0.10.10.5-0.5-0.1-0.60.50.70.5-0.1-0.00.20.10.00.0-0.50.3-0.2-0.10.10.0-0.0-0.3
Patch foraging water rate 6 sec0.10.20.6-0.4-0.0-0.60.30.80.60.20.30.70.50.40.4-0.50.50.10.10.30.30.20.0
Seeking ratio, delayed vs. immediate footshock1.72.09.4-1.8-2.5-1.41.71.9-1.1-0.3-0.4-0.2-0.7-0.8-0.7-3.1-0.7-0.6-1.1-1.3-0.9-1.7-1.7
Distance traveled before self-admin0.81.02.0-0.70.3-0.10.90.91.01.11.31.11.21.21.20.51.31.11.41.01.10.51.4
Distance traveled after self-admin0.91.13.5-1.9-1.8-1.11.81.8-0.51.21.10.90.50.60.5-1.60.40.80.5-0.00.4-0.40.0
Extensor digitorum longus weight0.10.20.90.80.00.7-0.9-0.4-0.30.1-0.10.30.20.30.30.70.20.70.50.30.50.30.9
Bone: elastic displacement0.50.61.20.9-0.2-0.3-1.0-0.5-0.4-1.0-0.8-0.7-0.6-0.9-0.9-0.4-0.7-0.9-1.0-0.5-0.7-0.1-1.1
Bone: elastic work0.00.10.30.1-0.6-0.5-0.20.2-0.3-0.3-0.10.0-0.0-0.1-0.1-0.3-0.0-0.1-0.10.10.10.2-0.3
Bone: endosteal estimation1.22.78.3-2.0-2.9-0.21.90.8-2.62.42.41.71.31.61.3-0.00.32.11.40.31.20.11.2
Bone: endosteal perimeter0.40.92.9-0.9-1.30.91.0-0.2-1.71.21.10.90.60.90.60.80.01.31.0-0.00.7-0.31.2
Epididymis fat weight2.99.932.6-2.31.8-4.12.34.25.72.12.23.03.22.83.2-1.04.32.22.73.93.03.71.5
Delta time in closed arm before/after self-admin0.90.81.7-0.6-0.1-0.40.80.50.20.80.81.31.21.31.30.70.91.11.11.01.10.90.9
Delta time in open arm before/after self-admin0.10.10.30.10.2-0.1-0.2-0.10.1-0.1-0.1-0.6-0.5-0.5-0.5-0.3-0.3-0.2-0.3-0.3-0.4-0.1-0.5
Diff in mean of infusions in LGA sessions0.60.83.81.22.01.4-1.1-1.01.2-0.7-0.6-0.6-0.6-0.20.01.40.2-0.20.20.1-0.00.10.7
Delay discount exponential model param0.30.31.70.51.30.5-0.4-0.11.30.60.5-0.10.20.20.10.60.5-0.10.80.40.20.10.6
Extinction: sum of active levers before priming0.20.21.40.20.11.2-0.1-0.6-0.40.10.2-0.0-0.20.20.30.8-0.1-0.10.6-0.10.1-0.10.4
Active lever presses in extinction session 60.30.31.11.01.00.3-0.9-0.80.5-0.8-0.20.10.2-0.00.11.00.20.0-0.00.60.20.90.2
Bone: final force2.13.45.5-1.9-0.8-2.21.82.31.12.02.02.32.12.12.1-0.52.11.91.91.92.01.71.3
Bone: final moment1.52.43.8-1.4-0.7-1.91.31.80.91.81.81.91.81.81.7-0.31.71.71.61.61.71.51.1
Food consumed during 24 hour testing period1.42.03.4-0.9-0.1-0.40.91.00.51.71.81.51.51.71.70.81.61.81.91.41.71.21.8
Glucose1.01.67.81.2-0.52.5-1.1-2.4-2.80.60.5-0.4-0.1-0.1-0.32.3-1.20.50.3-0.6-0.2-0.40.8
Heart weight0.60.96.1-1.2-2.5-1.31.00.5-2.20.40.41.00.60.40.3-0.9-0.40.8-0.3-0.10.30.2-0.3
Delay discount hyperbolic model param0.40.52.30.41.50.5-0.4-0.11.50.70.6-0.10.30.30.30.80.7-0.00.90.60.30.20.7
Intermittent access intake day 1-15 change0.20.41.1-0.8-0.8-0.40.80.5-0.4-0.4-0.4-0.5-0.3-0.7-0.5-1.0-0.4-0.5-0.8-0.6-0.4-0.7-0.6
Intermittent access intake escalation0.30.72.7-0.8-1.0-0.80.80.7-0.2-0.6-0.5-0.6-0.4-0.9-0.7-1.6-0.5-0.8-1.1-0.6-0.7-0.7-1.1
Intermittent access intake escalation 20.40.40.9-0.2-0.70.30.1-0.1-0.8-0.6-0.6-0.7-0.7-0.9-0.7-0.8-0.7-0.6-1.0-0.7-0.7-0.8-0.7
Intermitt. access day 1 inactive lever presses0.10.41.3-0.9-0.30.90.90.3-0.41.10.60.7-0.10.60.60.70.30.40.80.00.4-0.40.7
Intermitt. access day 15 inactive lever presses0.20.51.8-1.0-0.6-0.31.00.5-0.21.41.30.80.60.50.60.10.40.50.80.40.60.40.4
Intermitt. access escalation Index0.50.71.80.91.21.3-0.7-0.40.7-1.3-1.3-0.7-1.1-0.5-0.50.5-0.1-0.8-0.4-0.6-0.4-0.90.1
Intermittent access day 1 total infusions1.21.96.62.61.91.8-2.6-2.5-0.0-0.7-1.0-1.4-0.5-0.9-0.92.1-0.7-0.6-0.30.1-0.50.70.0
Intermittent access day 15 total infusions0.40.61.41.00.50.3-1.1-0.9-0.1-0.9-1.0-1.2-0.5-1.1-1.00.2-0.7-0.9-0.8-0.3-0.70.0-0.7
Intermittent access terminal intake (last 3 days)0.40.51.21.00.10.4-1.1-1.0-0.6-0.7-0.7-1.1-0.4-0.9-1.00.2-0.8-0.7-0.7-0.3-0.60.1-0.7
Intermittent access total infusions0.60.72.31.40.80.6-1.5-1.4-0.3-0.6-0.8-1.1-0.4-0.8-0.90.8-0.7-0.6-0.6-0.2-0.60.3-0.5
Intermittent access day 1 locomotion0.40.51.61.11.20.5-1.0-0.80.70.10.1-0.10.50.30.21.20.30.20.70.70.30.90.5
Intermittent access day 15 total locomotion0.30.61.5-0.6-0.6-0.80.60.70.10.90.90.81.20.80.9-0.20.71.01.00.90.80.90.6
Intermittent access total locomotion0.10.10.60.30.2-0.4-0.3-0.10.30.30.30.10.70.30.30.10.20.40.50.60.30.80.2
Intermittent access standard deviation0.71.54.3-2.1-1.1-1.82.01.60.21.31.01.41.41.11.0-0.90.90.80.50.90.90.90.2
Left kidney weight1.46.516.0-3.5-2.8-4.03.43.90.42.42.32.92.42.42.2-2.42.22.41.81.72.21.50.8
Right kidney weight1.88.114.8-3.8-2.3-3.83.73.80.83.13.13.33.03.02.8-1.72.73.02.52.32.71.91.5
Cocaine induced anxiety0.10.10.3-0.40.10.30.50.50.40.40.10.3-0.00.50.40.10.40.30.50.10.3-0.30.6
Post-drug Anxiety0.20.20.7-0.7-0.4-0.50.70.80.10.10.20.70.20.70.5-0.40.40.40.40.10.3-0.20.3
Baseline Anxiety0.10.10.4-0.3-0.5-0.70.20.2-0.3-0.20.00.30.60.30.3-0.10.10.3-0.00.20.30.40.1
Tail length0.93.422.5-2.4-4.7-1.52.11.3-3.91.61.70.90.60.40.1-2.1-0.90.80.1-0.90.1-1.0-0.6
Length with tail1.35.719.0-3.1-4.4-2.02.92.0-3.13.43.32.52.32.21.8-1.10.72.61.90.71.70.61.0
Length without tail3.411.119.3-3.0-1.7-2.23.02.70.24.44.14.13.94.24.00.83.24.33.83.23.82.93.3
Times rat made contact with spout1.11.33.10.70.2-0.4-0.8-0.30.2-1.4-1.3-1.2-1.3-1.4-1.4-1.2-1.0-1.6-1.8-0.9-1.3-0.7-1.7
Lifetime Intake0.40.51.81.30.70.5-1.4-1.3-0.3-0.2-0.4-0.8-0.1-0.5-0.60.9-0.5-0.4-0.20.0-0.30.5-0.3
Liver weight, left1.11.85.2-1.5-1.6-0.21.40.9-1.12.12.31.51.31.61.40.20.71.71.60.51.20.21.3
Liver weight, right0.61.13.4-0.9-1.70.40.90.1-1.81.31.01.20.91.31.00.60.21.31.10.30.90.11.1
Locomotor activity0.91.56.8-1.5-2.6-0.61.31.3-1.80.20.50.1-0.5-0.4-0.5-2.2-0.9-0.4-0.6-1.3-0.7-1.7-1.2
Locomotor testing distance0.30.62.3-1.3-1.5-0.11.21.1-0.80.81.10.30.10.20.1-1.2-0.20.20.4-0.6-0.1-1.0-0.3
Locomotor testing rearing0.61.23.2-1.5-1.0-0.31.61.2-0.21.61.81.31.21.21.1-0.20.81.21.40.60.90.20.8
Locomotion in novel chamber0.10.10.4-0.2-0.0-0.20.20.50.4-0.2-0.60.2-0.20.20.1-0.60.2-0.0-0.3-0.00.0-0.0-0.1
Locomotion in novel chamber post-restriction0.71.22.2-0.9-0.6-1.30.91.30.51.01.01.51.51.41.3-0.41.11.21.21.11.11.10.8
Fecal boli incidents, locomotor time 10.50.72.71.01.61.1-0.9-0.90.90.40.5-0.20.10.30.31.60.50.31.00.70.40.90.8
Change in fecal boli incidents, locomotor task0.80.82.8-1.3-1.7-0.51.30.8-1.31.00.91.00.81.00.9-0.30.20.80.60.10.6-0.20.5
Time >=10cm from walls, locomotor time 13.33.56.6-2.0-1.0-1.22.22.00.32.02.32.31.82.52.60.21.92.02.31.52.01.11.9
Bouts of movement, locomotor time 10.70.82.30.30.10.1-0.2-0.1-0.1-1.4-1.5-1.0-1.2-1.1-1.2-0.7-0.7-1.0-1.0-1.0-1.0-1.2-0.9
Total resting periods, locomotor time 10.50.61.60.30.10.3-0.3-0.3-0.2-1.1-1.3-1.0-1.0-0.9-1.1-0.4-0.7-0.8-0.8-0.9-0.8-1.0-0.6
Rest time, locomotor task time 10.20.30.90.2-0.30.5-0.1-0.5-0.7-0.3-0.2-0.7-0.9-0.4-0.7-0.2-0.7-0.5-0.5-0.7-0.7-0.7-0.6
Distance moved, locomotor task time 10.50.72.0-0.7-0.6-1.00.60.80.20.90.91.11.40.71.1-0.10.80.90.70.80.90.80.7
Vertical activity count, locomotor time 10.81.93.9-1.1-0.4-1.81.01.50.71.41.51.92.01.41.9-0.11.51.51.31.31.41.40.9
Time >=10cm from walls, locomotor time 22.03.07.5-1.6-1.3-1.01.60.9-0.92.52.71.82.12.32.20.61.22.02.01.31.71.41.6
Bouts of movement, locomotor time 20.71.12.1-0.6-1.3-0.40.50.3-1.2-1.0-1.4-0.7-0.9-1.0-1.0-1.4-1.1-1.0-1.0-1.4-1.1-1.4-1.4
Total resting periods, locomotor time 21.12.03.8-0.3-1.5-0.00.2-0.1-1.7-1.5-1.7-1.2-1.4-1.4-1.5-1.5-1.6-1.4-1.4-2.0-1.5-1.9-1.8
Rest time, locomotor task time 20.10.10.8-0.00.20.90.2-0.1-0.1-0.3-0.30.0-0.40.20.20.60.10.20.3-0.20.2-0.50.6
Distance moved, locomotor task time 21.72.05.1-0.40.2-1.40.30.50.81.71.71.52.31.41.70.71.41.61.31.91.52.11.3
Vertical activity count, locomotor time 21.52.04.8-0.5-0.1-1.20.40.50.41.81.81.62.21.61.90.71.31.81.51.71.52.01.3
Light reinforcement 11.33.26.3-1.90.2-1.41.91.91.72.52.51.62.12.12.00.12.11.61.81.71.81.21.7
Light reinforcement 21.52.34.2-1.20.3-0.41.31.01.12.12.11.41.71.81.81.01.81.41.91.71.81.41.8
Bone: marrow area1.32.98.7-2.1-3.0-0.32.10.9-2.52.52.51.81.41.71.4-0.10.42.21.50.41.40.21.3
Bone: maximum diameter0.20.42.5-0.2-0.81.10.3-0.8-1.60.0-0.2-0.1-0.4-0.2-0.20.5-0.70.3-0.1-0.6-0.2-0.70.3
Bone: maximum force1.01.82.8-1.3-0.6-1.41.31.50.71.51.51.71.51.61.5-0.21.51.51.51.41.51.31.0
Bone: maximum moment0.71.21.8-0.9-0.5-1.10.81.00.31.31.31.31.21.31.20.11.11.31.21.11.21.10.9
Mean time between licks in bursts0.51.23.90.6-0.32.0-0.4-1.4-1.7-0.8-0.8-1.0-1.2-0.7-1.00.5-1.4-0.6-0.7-1.5-1.1-1.6-0.3
Mean num. licks in bursts0.20.31.50.00.5-1.2-0.00.41.1-0.5-0.50.10.1-0.2-0.2-0.70.2-0.5-0.50.4-0.10.7-0.7
Cd content in liver2.93.26.80.52.20.3-0.4-0.42.01.41.21.42.11.81.92.62.01.71.92.41.92.62.2
Co content in liver2.32.74.2-1.50.1-1.51.51.31.21.81.72.02.11.81.90.41.81.81.71.91.81.91.4
Cu content in liver0.70.92.51.00.9-0.3-1.0-0.11.0-1.6-1.6-0.8-0.8-1.0-1.0-0.8-0.4-1.2-1.3-0.5-0.9-0.4-1.1
Fe content in liver0.50.61.3-0.40.3-0.90.40.81.20.80.80.80.80.80.8-0.11.00.70.71.00.81.00.5
K content in liver0.50.51.21.01.10.9-0.9-0.70.6-1.0-1.0-0.7-0.9-0.7-0.60.4-0.3-0.5-0.4-0.3-0.4-0.40.0
Mg content in liver0.80.82.91.00.51.7-0.8-1.0-0.4-1.4-1.6-0.8-0.9-0.8-0.60.7-0.6-0.6-0.5-0.8-0.6-1.10.2
Mn content in liver0.50.52.60.50.21.6-0.3-0.8-0.60.50.20.20.20.60.51.50.10.80.80.10.5-0.11.3
Na content in liver0.80.82.30.1-0.4-0.4-0.30.40.0-1.1-0.8-0.7-1.1-1.0-1.0-1.5-0.7-1.1-1.2-1.0-1.0-1.2-1.3
Rb content in liver0.60.62.21.11.30.7-1.0-0.60.80.0-0.10.20.50.60.71.50.70.50.70.80.60.91.0
Se content in liver1.61.85.60.5-1.11.5-0.5-1.3-2.4-1.2-1.2-1.2-1.4-1.3-1.4-0.0-1.8-1.0-1.3-1.8-1.3-1.9-0.9
Sr content in liver0.60.51.30.10.20.4-0.2-0.4-0.20.90.90.70.80.70.61.20.50.90.70.80.81.01.0
Zn content in liver0.50.51.7-0.10.50.60.2-0.60.00.90.70.70.80.70.81.30.50.90.80.70.70.81.2
Bone: minimum diameter0.40.71.8-0.5-1.20.40.60.1-1.30.80.81.00.70.80.70.60.21.31.00.20.80.01.1
Time in familiar zone, hab. session 11.71.62.81.61.50.3-1.7-1.00.9-1.6-1.6-1.4-1.3-1.6-1.4-0.4-0.9-1.5-1.4-0.7-1.3-0.3-1.4
Time in novel zone, hab. session 11.51.53.5-1.9-1.7-0.51.91.0-1.11.71.71.31.11.41.20.00.61.31.00.51.00.20.9
Total zone transitions, hab. session 10.40.61.30.70.60.8-0.6-0.40.3-1.1-0.9-1.0-0.9-1.0-0.8-0.0-0.5-1.0-0.6-0.7-0.7-1.0-0.5
Total locomotion distance, hab. session 10.40.51.51.01.00.9-0.8-0.40.7-1.1-1.2-0.8-0.8-0.7-0.60.2-0.2-0.8-0.3-0.5-0.5-0.7-0.2
Locomotion velocity, hab. session 10.40.51.60.80.60.7-0.7-0.30.3-1.1-1.3-0.8-0.8-0.8-0.7-0.1-0.4-0.8-0.5-0.6-0.6-0.8-0.4
Time in familiar zone, hab. session 20.50.52.9-0.8-0.2-0.90.81.20.8-0.5-0.4-0.0-0.4-0.4-0.2-1.7-0.0-0.6-0.4-0.5-0.6-0.8-0.9
Time in novel zone, hab. session 20.30.31.00.1-0.30.1-0.2-0.7-0.90.80.80.20.60.40.31.00.00.50.10.50.50.90.5
Total zone transitions, hab. session 20.20.21.8-0.10.80.10.20.71.4-0.3-0.40.20.10.20.3-0.10.70.20.40.20.3-0.20.5
Total locomotion distance, hab. session 20.50.63.70.81.80.9-0.60.11.9-0.9-1.1-0.3-0.3-0.00.10.50.6-0.30.20.20.1-0.20.6
Locomotion velocity, hab. session 20.60.83.61.11.91.2-0.9-0.31.7-1.1-1.3-0.6-0.6-0.2-0.20.70.3-0.50.0-0.1-0.2-0.50.5
Novel to familiar place preference ratio0.30.30.70.70.10.4-0.8-0.8-0.6-0.4-0.2-0.8-0.5-0.5-0.60.3-0.6-0.6-0.7-0.3-0.4-0.1-0.4
Novelty place preference0.30.30.90.5-0.30.3-0.6-0.7-0.9-0.4-0.2-0.8-0.5-0.5-0.70.1-0.7-0.6-0.9-0.5-0.5-0.3-0.6
Time in novel zone, NPP test0.40.41.30.4-0.60.2-0.6-0.7-1.1-0.5-0.4-0.8-0.5-0.6-0.7-0.1-0.9-0.7-1.0-0.6-0.6-0.4-0.7
Total zone transitions, NPP test0.81.24.11.62.01.8-1.4-1.31.0-1.4-1.4-1.1-0.8-0.9-0.71.4-0.2-0.7-0.3-0.1-0.4-0.30.3
Total locomotion distance, NPP test1.31.77.82.02.81.6-1.8-1.21.9-1.0-1.2-0.40.00.00.22.20.80.00.40.90.50.91.2
Locomotion velocity, NPP test1.52.110.42.23.21.9-2.0-1.32.3-1.0-1.2-0.7-0.2-0.10.12.40.8-0.10.50.90.40.81.3
Intraocular pressure0.20.31.60.41.30.1-0.4-0.21.30.30.50.00.20.20.20.40.40.20.50.60.20.70.4
Delta distance traveled before/after self-admin1.21.35.6-1.1-2.4-1.10.80.6-2.00.1-0.1-0.3-0.6-0.7-0.8-2.0-1.1-0.3-1.1-1.1-0.8-0.9-1.4
Delta ambulatory time before/after self-admin1.01.25.7-1.2-2.4-1.11.00.8-2.00.1-0.0-0.2-0.5-0.5-0.7-1.9-1.0-0.2-1.0-1.1-0.7-1.0-1.3
Parametrial fat weight2.14.99.1-1.60.6-2.51.52.63.02.01.72.52.32.42.5-0.13.02.02.22.72.52.32.0
Pavlov. Cond. lever latency4.45.511.3-3.1-0.8-3.43.03.21.92.72.62.72.42.32.3-1.52.42.11.92.12.01.91.0
Pavlov. Cond. magazine entry latency3.84.86.91.8-0.71.9-1.9-2.0-2.3-2.6-2.4-2.6-2.6-2.5-2.6-0.4-2.6-2.2-2.4-2.5-2.3-2.4-1.8
Pavlov. Cond. change in total contacts1.81.93.71.1-0.81.1-1.2-1.3-1.9-1.6-1.5-1.5-1.4-1.4-1.5-0.2-1.8-1.3-1.4-1.6-1.4-1.5-1.2
Pavlov. Cond. index score4.15.27.72.70.12.8-2.7-2.7-2.1-2.8-2.7-2.6-2.5-2.4-2.40.7-2.5-2.0-2.0-2.2-2.0-2.1-1.2
Pavlov. Cond. latency score4.35.48.22.70.12.9-2.7-2.7-2.2-2.9-2.8-2.6-2.6-2.4-2.40.7-2.6-2.1-2.1-2.3-2.1-2.2-1.3
Pavlov. Cond. lever contacts2.83.39.22.81.03.0-2.7-2.7-1.3-2.0-2.0-2.0-1.6-1.5-1.51.9-1.6-1.3-1.0-1.2-1.1-1.1-0.1
Pavlov. Cond. magazine entry number2.73.44.7-1.60.4-1.61.61.71.92.12.02.22.22.12.10.32.21.81.92.11.92.01.5
Pavlov. Cond. intertrial magazine entries1.21.43.9-0.11.6-0.60.20.32.01.10.90.91.41.11.31.01.50.81.11.71.11.80.9
Pavlov. Cond. lever-magazine prob. diff.4.15.17.52.70.22.7-2.7-2.7-2.0-2.7-2.6-2.7-2.5-2.4-2.40.8-2.4-2.0-2.0-2.2-2.0-2.0-1.2
Pavlov. Cond. response bias2.83.55.32.20.12.3-2.2-2.2-1.8-2.1-2.1-2.3-2.1-2.1-2.00.5-2.1-1.6-1.6-1.9-1.7-1.8-1.0
Pavlov. Cond. lever latency0.70.91.7-1.0-0.10.11.30.50.11.31.11.00.81.31.30.80.91.11.20.81.00.51.3
Pavlov. Cond. magazine entry latency0.40.51.71.20.20.9-1.3-1.1-0.7-0.7-0.6-0.6-0.3-0.5-0.60.7-0.6-0.3-0.5-0.3-0.3-0.1-0.1
Pavlov. Cond. change in total contacts0.71.12.20.6-0.7-0.1-0.8-0.5-1.0-1.4-1.2-0.9-0.9-1.3-1.3-1.0-1.3-1.2-1.4-1.1-1.2-0.9-1.5
Pavlov. Cond. index score0.60.91.81.2-0.10.4-1.3-0.9-0.8-1.3-1.1-0.9-0.7-1.1-1.2-0.3-1.1-0.9-1.1-0.8-0.9-0.6-0.9
Pavlov. Cond. latency score0.50.71.20.9-0.30.2-1.1-0.7-0.7-1.1-1.0-0.8-0.6-1.0-1.0-0.4-0.9-0.8-1.0-0.7-0.8-0.5-0.9
Pavlov. Cond. lever contacts0.50.71.30.80.1-0.2-1.0-0.4-0.1-1.1-0.8-0.9-0.6-1.1-1.1-0.7-0.8-0.9-1.1-0.6-0.9-0.4-1.1
Pavlov. Cond. magazine entry number0.10.10.9-0.8-0.3-0.40.90.50.10.40.40.2-0.10.20.2-0.50.10.00.1-0.10.0-0.2-0.1
Pavlov. Cond. intertrial magazine entries0.60.82.8-0.4-0.50.80.7-0.3-0.9-0.6-0.6-0.9-1.2-0.9-0.9-0.6-1.1-0.9-0.7-1.4-1.1-1.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.50.71.61.1-0.10.3-1.3-0.8-0.6-1.2-1.0-0.8-0.6-1.0-1.0-0.3-0.9-0.8-1.0-0.7-0.8-0.5-0.8
Pavlov. Cond. response bias0.71.02.51.40.20.5-1.6-0.9-0.4-1.3-1.1-1.1-0.9-1.2-1.3-0.2-1.0-1.0-1.1-0.8-1.0-0.6-1.0
Time in closed arm before self-admin0.10.10.6-0.1-0.60.4-0.0-0.2-0.70.40.1-0.0-0.10.0-0.1-0.2-0.30.1-0.0-0.3-0.1-0.2-0.0
Time in closed arm after self-admin0.10.10.40.10.00.3-0.0-0.1-0.00.10.20.60.20.60.40.50.30.50.50.50.40.50.3
Time in open arm before self-admin1.31.42.31.1-0.20.8-1.2-1.2-1.2-1.0-0.8-1.4-1.2-1.4-1.4-0.2-1.5-1.5-1.5-1.2-1.3-1.2-1.2
Time in open arm after self-admin0.80.91.60.6-0.30.5-0.8-0.7-0.9-0.8-0.8-1.2-1.0-1.3-1.2-0.5-1.1-1.0-1.3-1.1-1.0-0.8-1.0
Bone: periosteal estimation0.71.66.3-1.8-2.5-0.71.81.1-1.81.61.51.30.81.00.8-0.70.21.50.90.00.8-0.20.6
Bone: periosteal perimeter0.30.42.6-0.9-1.60.01.00.2-1.60.50.50.50.10.20.1-0.3-0.30.50.2-0.40.1-0.60.1
Bone: post-yield work0.50.71.8-0.3-0.10.80.4-0.3-0.51.21.10.60.70.90.81.30.51.11.20.50.80.41.3
Progressive ratio test 1 active lever presses0.30.41.80.80.70.7-0.8-1.2-0.20.80.4-0.20.40.20.21.3-0.10.20.70.50.20.90.5
Progressive ratio test 1 breakpoint0.30.41.70.70.60.7-0.7-1.1-0.30.80.4-0.20.40.20.21.3-0.10.20.60.50.20.80.5
Progressive ratio test 1 inactive lever presses0.50.82.1-0.51.2-0.20.60.21.41.10.50.80.70.81.00.81.00.61.21.10.81.10.8
Progressive ratio test 2 active lever presses0.30.41.00.91.00.6-0.9-0.90.3-0.3-0.6-0.8-0.6-0.6-0.60.6-0.3-0.4-0.2-0.1-0.40.1-0.2
Progressive ratio test 2 breakpoint0.40.41.00.91.00.7-0.9-1.00.3-0.4-0.7-0.9-0.7-0.8-0.80.5-0.4-0.5-0.4-0.1-0.50.0-0.3
Progressive ratio test 2 inactive lever presses0.30.52.80.90.91.2-0.8-1.6-0.50.3-0.1-0.4-0.2-0.2-0.11.7-0.3-0.10.30.2-0.00.40.5
Incentive Sensitization - Responses0.60.91.80.70.30.7-0.7-0.5-0.1-1.1-1.3-1.1-1.3-1.3-1.3-0.4-0.8-0.9-1.1-0.9-1.0-1.0-0.9
Incentive Sensitization - Breakpoint0.60.81.70.70.50.6-0.7-0.40.2-1.1-1.2-1.1-1.3-1.2-1.3-0.3-0.7-0.9-1.1-0.8-0.9-0.9-0.8
Sum of active levers in priming session hrs 5-60.40.41.20.6-0.20.6-0.6-0.9-1.1-0.5-0.2-0.7-0.6-0.7-0.60.3-0.9-0.6-0.2-0.7-0.7-0.5-0.5
Progressive ratio2.43.811.2-3.2-2.4-3.23.03.40.41.31.52.11.71.51.5-2.51.41.30.80.91.20.6-0.0
Food seeking constrained by brief footshock0.10.10.30.2-0.0-0.2-0.3-0.3-0.20.10.5-0.2-0.1-0.2-0.2-0.2-0.3-0.2-0.1-0.0-0.30.2-0.6
Seeking ratio, punishment vs. effort1.92.78.02.31.32.6-2.2-2.8-1.0-1.0-1.0-2.1-1.6-1.5-1.61.6-1.7-1.4-1.0-1.1-1.5-0.8-0.6
Retroperitoneal fat weight0.31.53.5-0.11.1-0.60.10.71.90.80.61.31.21.31.30.91.71.11.41.71.41.61.4
Reaction time number correct0.51.03.0-1.7-0.4-1.71.71.40.91.21.21.10.80.70.8-0.90.80.30.30.70.50.6-0.0
Reaction time mean minus median0.81.95.32.20.82.3-2.2-1.9-0.9-1.7-1.7-1.4-1.1-1.1-1.11.2-1.1-0.8-0.7-1.0-0.9-0.9-0.1
Reaction time mean minus median AUC1.02.57.82.81.52.6-2.7-2.7-0.8-1.5-1.4-1.6-0.9-1.0-1.02.3-1.1-0.7-0.4-0.6-0.7-0.20.3
Reaction time num false alarms0.30.41.7-0.4-1.00.00.40.2-1.0-0.5-0.3-0.2-0.8-0.4-0.6-0.8-0.7-0.4-0.3-1.0-0.7-1.3-0.6
Reaction time num false alarms AUC0.71.03.1-0.8-1.7-0.20.80.5-1.5-0.6-0.4-0.3-1.0-0.6-0.9-1.5-1.0-0.6-0.7-1.4-0.9-1.8-1.0
Reaction time trials correct on left0.51.03.0-1.7-0.4-1.71.71.40.91.21.21.10.80.70.8-0.90.80.30.30.70.50.6-0.0
Reaction time trials on left0.51.02.9-1.7-0.4-1.61.61.30.81.21.21.00.80.70.8-0.90.80.30.30.70.50.6-0.0
Reaction time mean0.91.56.42.11.42.3-2.0-1.9-0.3-0.5-0.6-0.6-0.0-0.00.12.5-0.10.30.70.20.30.41.2
Reaction time mean AUC0.91.46.42.11.42.2-2.0-1.9-0.3-0.5-0.5-0.6-0.0-0.00.12.5-0.10.30.60.20.20.41.1
Median of all reaction times0.81.26.01.61.31.8-1.4-1.4-0.0-0.0-0.2-0.10.40.40.52.50.30.71.00.60.70.81.5
Reaction time omissions0.50.73.31.50.91.8-1.4-1.1-0.1-0.8-0.7-0.7-0.4-0.3-0.21.4-0.2-0.10.2-0.3-0.1-0.30.6
Reaction time false alarm rate1.11.54.00.4-1.40.8-0.4-0.5-2.0-1.4-1.2-0.9-1.4-1.1-1.3-0.8-1.5-0.8-1.0-1.8-1.3-2.0-1.0
Reaction time premature initiation rate0.30.41.1-0.20.00.00.20.30.31.00.80.60.80.80.60.30.60.60.70.70.70.70.7
Reaction time premature initiations0.71.33.0-1.4-0.4-1.11.41.20.71.71.51.21.31.31.1-0.41.10.91.01.11.01.00.7
Std. dev. reaction times1.01.95.32.10.22.3-2.0-2.1-1.6-1.5-1.4-1.4-1.1-1.1-1.11.3-1.4-0.7-0.6-1.2-0.9-1.0-0.1
Reaction time trials completed0.51.02.9-1.7-0.4-1.61.61.30.81.21.21.00.80.70.8-0.90.80.30.30.70.50.6-0.0
Reaction time trials AUC0.61.12.9-1.7-0.2-1.61.71.31.01.31.21.10.90.80.9-0.70.90.40.50.90.70.70.2
Run reversals in cocaine runway, females0.40.41.30.50.8-0.5-0.5-0.10.90.80.30.40.60.60.60.60.60.60.50.90.61.20.5
Run reversals in cocaine runway, males0.50.52.00.80.31.4-0.8-0.9-0.5-0.2-0.4-1.0-0.7-0.7-0.60.4-0.7-0.4-0.5-0.7-0.6-0.7-0.2
Latency to leave start box in cocaine runway0.30.41.80.90.71.3-0.8-0.8-0.1-0.3-0.1-0.0-0.20.30.21.30.10.30.40.20.30.20.8
Latency to leave start box in cocaine runway, F0.40.52.31.01.01.4-0.9-1.00.1-0.10.3-0.1-0.10.40.21.50.00.20.60.20.20.20.6
Latency to leave start box in cocaine runway, M0.10.10.3-0.1-0.10.10.10.20.0-0.2-0.30.3-0.00.30.30.10.40.50.10.30.40.20.5
Std. dev. time between licks in bursts0.70.94.50.5-1.21.5-0.5-0.9-2.1-0.7-1.0-0.3-0.8-0.4-0.60.1-1.2-0.0-0.4-1.3-0.6-1.50.0
Total sessions with >9 infusions0.20.30.90.8-0.10.3-0.8-1.0-0.90.10.2-0.6-0.3-0.4-0.60.3-0.8-0.5-0.1-0.3-0.60.1-0.7
Short access day 1 total inactive lever presses0.40.62.91.10.41.2-1.1-1.5-1.10.40.5-0.0-0.10.20.01.7-0.50.10.70.1-0.00.40.4
Short access day 10 total inactive lever presses0.10.20.9-0.80.40.30.90.80.80.2-0.30.1-0.60.00.2-0.20.4-0.30.3-0.4-0.1-0.8-0.0
Short access day 1 total infusions0.50.62.81.40.51.2-1.4-1.7-0.90.00.1-0.8-0.3-0.3-0.51.3-0.7-0.5-0.1-0.1-0.40.3-0.1
Short access day 10 total infusions0.30.41.01.01.00.6-1.0-1.00.1-0.1-0.4-0.7-0.1-0.4-0.51.0-0.3-0.60.10.1-0.30.4-0.3
Short access total infusions0.40.52.31.40.80.9-1.3-1.5-0.50.10.1-0.60.0-0.2-0.41.4-0.5-0.30.20.2-0.20.7-0.1
Short access day 1 locomotion0.40.41.61.10.91.2-1.0-0.90.1-0.3-0.5-0.8-0.6-0.4-0.50.8-0.4-0.60.1-0.4-0.4-0.40.0
Short access day 10 total locomotion0.81.55.5-2.0-2.3-0.72.01.3-1.51.61.70.90.91.00.8-1.20.11.01.1-0.10.5-0.50.3
Short access total locomotion0.40.41.5-0.2-0.40.40.3-0.1-0.61.21.00.50.80.80.70.60.20.71.20.30.50.30.6
One hour access (0.3 mA shock)1.21.32.71.51.21.3-1.5-0.90.5-1.3-1.7-1.5-1.5-1.4-1.30.1-0.7-1.1-1.1-0.8-1.0-0.9-0.6
Compulsive drug intake0.20.21.20.20.51.1-0.00.30.6-0.1-0.2-0.2-0.7-0.00.30.30.40.30.2-0.30.2-0.90.9
One hour access (shock baseline)0.40.61.91.30.70.2-1.4-1.00.1-0.9-1.1-0.8-0.3-0.8-1.00.2-0.6-0.8-0.8-0.0-0.60.4-0.8
Social response proportion0.50.61.5-1.0-1.2-0.31.00.5-0.91.00.91.10.60.90.90.10.30.80.70.30.70.30.4
Social responses0.50.62.9-1.3-1.7-0.61.31.0-1.00.50.70.70.00.40.2-1.1-0.10.30.2-0.40.0-0.6-0.3
Social time0.30.42.9-0.1-0.51.40.30.2-0.6-0.5-0.4-0.3-0.8-0.2-0.2-0.2-0.4-0.30.0-1.1-0.5-1.70.0
Soleus weight0.61.75.0-1.1-1.51.11.2-0.3-2.21.91.41.20.91.51.21.40.21.91.50.21.10.01.8
Bone: stiffness0.91.42.3-1.2-0.0-1.31.21.51.21.41.31.31.31.41.3-0.31.41.21.21.21.21.00.9
Tibialis anterior weight0.10.31.3-0.10.2-1.1-0.01.01.20.00.00.50.10.30.3-1.00.60.20.10.40.30.3-0.0
Time to tail flick, vehicle, before self-admin0.40.42.4-0.60.5-0.40.81.31.5-0.6-0.50.3-0.10.30.4-0.80.7-0.10.60.00.2-0.50.3
Time to tail flick, vehicle, after self-admin0.20.20.60.70.00.6-0.6-0.8-0.7-0.30.4-0.6-0.5-0.4-0.60.4-0.6-0.3-0.1-0.5-0.5-0.5-0.2
Time to tail flick, test, before self-admin1.01.13.1-0.3-0.5-0.20.20.60.1-1.5-1.5-0.7-1.0-1.1-1.1-1.7-0.7-1.2-1.1-1.1-1.1-1.4-1.3
Time to tail flick, test, after self-admin2.72.85.11.60.81.0-1.6-1.3-0.1-2.1-2.0-2.0-2.3-2.1-2.2-0.3-1.5-2.1-1.8-1.5-1.8-1.5-1.5
Delta time to tail flick, vehicle, before/after SA1.21.24.41.90.91.0-2.0-2.1-0.7-0.6-0.3-1.2-0.6-1.0-1.01.3-1.0-0.8-0.8-0.3-0.70.3-0.5
Delta time to tail flick, test, before/after SA0.40.42.31.11.50.5-1.0-0.71.0-0.4-0.4-0.3-0.3-0.1-0.01.20.3-0.10.00.50.20.60.5
Tibia length0.92.47.6-2.7-2.6-0.92.81.7-1.52.01.81.51.11.31.2-0.80.61.51.30.11.1-0.30.8
Ambulatory time before self-admin0.10.20.50.10.50.40.00.20.70.30.40.20.40.30.40.30.50.30.50.40.40.10.6
Ambulatory time after self-admin0.60.72.8-1.4-1.7-0.71.41.2-0.80.80.60.50.20.20.1-1.30.00.40.0-0.30.1-0.6-0.2
Bone: tissue strength0.60.61.60.20.4-0.1-0.2-0.10.30.80.90.60.90.90.91.10.80.81.01.10.91.20.9
Total heroin consumption0.20.20.7-0.7-0.50.00.70.4-0.2-0.5-0.4-0.2-0.6-0.4-0.3-0.6-0.3-0.5-0.5-0.6-0.4-0.9-0.4
Bone: trabecular number1.11.88.82.23.01.3-2.1-1.22.2-1.5-1.7-1.1-0.8-0.8-0.61.10.0-1.3-0.60.1-0.60.1-0.1
Bone: trabecular spacing1.41.98.1-2.0-2.9-1.51.81.3-2.01.82.01.01.00.90.8-0.90.21.30.80.20.80.20.2
Bone: trabecular thickness0.81.05.91.32.40.7-1.1-0.62.2-1.1-1.4-0.3-0.3-0.3-0.10.80.5-0.3-0.10.50.00.50.4
Bone: trabecular tissue density0.81.13.4-0.0-1.4-0.0-0.2-0.6-1.8-0.3-0.1-1.0-1.0-1.1-1.3-1.0-1.5-0.9-1.3-1.3-1.2-1.1-1.4
Water consumed over 24 hours0.00.00.2-0.1-0.40.20.1-0.0-0.50.00.0-0.1-0.20.0-0.00.0-0.10.2-0.1-0.20.1-0.20.2
Number of responses in last shaping day0.60.76.90.0-1.70.7-0.2-0.8-2.60.70.6-0.2-0.10.1-0.40.0-1.00.3-0.0-0.6-0.3-0.5-0.1