Ptprc

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Ptprc 0.08 0.06 2.1e-04 0.02 0.03 0.03 0.02 1.2e-03 4.2e-05 4.5e-05 1.4e-03
2 Adipose intron excision ratio chr13_52200543_52204139 0.11 0.06 1.9e-07 0.05 0.04 0.03 0.04 7.3e-06 3.2e-05 1.0e-04 1.8e-05
3 Adipose isoform ratio NM_001109890.2 0.08 0.05 1.1e-07 0.04 0.04 0.04 0.04 8.4e-06 2.2e-05 2.5e-05 2.5e-05
4 Liver mRNA stability Ptprc 0.1 0.05 1.3e-10 0.06 0.07 0.06 0.06 8.8e-07 5.3e-08 3.0e-07 1.1e-07
5 Adipose intron excision ratio chr13_52200543_52210148 0.03 0.02 1.8e-03 0.01 0.01 0.01 0.01 1.7e-02 1.7e-02 2.8e-02 3.3e-02
6 Brain gene expression Ptprc 0.11 0.06 1.9e-03 0.01 0.03 0.04 0.01 8.3e-02 4.3e-04 2.2e-04 3.8e-02
7 Liver gene expression Ptprc 0.18 0.08 6.7e-05 0 0.04 0.03 0 2.1e-01 4.0e-05 7.2e-04 1.7e-01
8 NAcc gene expression Ptprc 0.05 0.03 7.8e-03 0.01 0.01 0.01 0.01 3.1e-03 2.8e-03 1.0e-02 1.0e-02
9 Adipose mRNA stability Ptprc 0.11 0.05 8.6e-10 0.05 0.07 0.07 0.06 7.0e-06 2.2e-08 5.5e-08 9.1e-08
10 Adipose gene expression Ptprc 0.05 0.03 4.6e-04 0.03 0.02 0.02 0.03 2.2e-04 1.3e-03 1.2e-03 1.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.23.87.5-2.52.2-2.4-2.7-2.62.00.10.2-1.7-0.2
Area under the delay curve1.82.13.10.8-1.41.61.61.8-1.6-1.4-1.7-0.3-1.5
BMI with tail2.89.617.9-4.23.8-3.9-3.3-3.03.51.90.5-3.5-0.1
BMI without tail3.09.317.7-3.63.9-4.2-3.9-3.82.61.81.5-1.41.5
Body weight3.515.324.3-4.94.6-4.9-4.2-3.84.72.30.6-4.9-0.8
Weight adjusted by age0.50.81.6-0.80.8-1.1-1.0-1.10.40.10.80.81.3
Bone surface3.86.912.4-3.33.3-3.3-3.5-3.32.80.90.7-2.00.5
Bone volume3.25.810.5-2.93.0-3.0-3.2-3.12.60.80.7-1.80.4
Breakpoint value in progressive ratio session0.60.71.51.2-0.70.91.11.0-1.10.30.00.6-0.2
Number of licking bursts0.00.00.1-0.2-0.2-0.2-0.2-0.20.0-0.3-0.4-0.0-0.2
Context. condit. distance diff. score1.11.44.42.1-1.11.20.70.5-0.9-0.70.71.80.9
Locomotion velocity, session 10.80.91.80.10.8-1.0-0.7-0.91.31.31.4-0.40.5
Locomotion distance, session 10.40.61.0-0.10.8-0.9-0.7-0.81.00.81.0-0.40.3
Locomotion velocity, session 20.10.10.4-0.70.2-0.3-0.4-0.30.50.3-0.1-0.2-0.1
Locomotion distance, session 20.40.61.3-0.90.2-0.1-0.8-0.8-0.6-1.0-0.51.11.0
Locomotion velocity, session 30.50.51.30.40.6-0.5-0.3-0.40.51.01.10.61.1
Locomotion distance, session 32.32.56.4-0.21.5-1.5-1.7-1.90.50.92.01.62.5
Stereotopy head waving bouts, day 30.50.51.20.4-0.91.10.90.9-0.6-0.5-0.60.80.2
Stereotopy head waving duration, day 30.81.02.41.1-1.31.31.51.5-0.00.4-0.2-0.1-0.6
Locomotion velocity, session 71.41.53.60.31.0-1.2-1.3-1.60.70.71.70.91.9
Locomotion distance, session 71.21.54.71.10.5-0.6-0.7-1.00.71.22.21.21.9
Stereotopy head waving bouts, day 71.31.53.31.8-1.61.61.71.6-0.6-0.4-0.20.4-0.7
Stereotopy head waving duration, day 70.60.82.41.5-1.21.01.21.1-0.40.10.30.6-0.0
Locomotion velocity, session 80.60.72.21.2-0.20.20.1-0.10.60.81.50.91.2
Locomotion distance, session 81.01.55.81.5-0.80.90.1-0.2-0.9-0.90.92.41.7
Degree of sensitization distance0.20.20.50.7-0.40.30.50.50.20.60.2-0.6-0.6
Degree of sensitization stereotypy1.01.13.92.0-1.21.11.41.3-0.10.30.60.1-0.5
Conditioned locomotion0.70.83.0-1.20.5-0.4-0.2-0.00.4-0.1-1.0-1.7-1.4
Cocaine response after cond. corrected0.10.10.4-0.60.0-0.2-0.5-0.4-0.1-0.6-0.40.10.1
Cocaine response after cond. not corrected0.70.81.7-1.00.6-0.7-1.3-1.3-0.3-0.9-0.00.81.1
Cocaine response before conditioning0.60.72.3-0.00.5-0.4-0.9-1.0-0.7-0.70.41.41.5
Saline control response0.20.21.2-0.1-0.1-0.1-0.3-0.3-0.3-0.4-0.01.10.8
Bone: connectivity density2.94.68.9-2.82.4-2.5-3.0-2.82.20.20.1-2.0-0.4
Bone: cortical apparent density2.23.07.00.9-1.81.91.11.1-2.5-2.6-1.91.7-0.4
Bone: cortical area2.74.18.1-2.42.9-2.6-2.3-2.22.31.10.5-2.0-0.1
Bone: cortical porosity2.93.15.5-2.42.3-2.3-2.3-2.21.70.70.5-1.00.5
Bone: cortical porosity2.02.14.5-2.11.8-1.8-2.0-1.91.40.30.2-0.80.4
Bone: cortical thickness0.91.43.7-1.70.6-0.4-0.7-0.40.0-1.4-1.9-1.4-1.5
Bone: cortical thickness1.21.43.6-1.91.2-1.1-1.7-1.6-0.2-1.0-0.7-0.00.6
Bone: cortical tissue density2.12.96.40.9-1.81.91.11.1-2.5-2.5-1.81.7-0.4
Condit. Reinf. active minus inactive responses0.30.30.6-0.70.5-0.6-0.8-0.70.1-0.7-0.5-0.5-0.3
Condit. Reinf. active-inactive response ratio0.40.41.6-0.30.1-0.10.10.20.1-0.6-0.8-1.2-1.3
Condit. Reinf. active responses0.60.81.9-0.80.7-0.8-1.4-1.4-0.2-0.80.00.61.0
Condit. Reinf. inactive responses1.01.23.6-0.60.6-0.7-1.3-1.4-0.1-0.40.61.61.9
Incentive salience index mean0.81.02.9-1.70.9-1.0-1.4-1.30.0-1.1-0.8-0.30.2
Condit. Reinf. lever presses0.40.62.2-1.50.3-0.3-0.9-0.8-0.4-1.0-0.80.30.4
Condit. Reinf. active minus inactive responses3.64.711.9-0.82.0-2.2-2.2-2.60.71.52.62.03.5
Condit. Reinf. active-inactive response ratio2.32.67.30.31.0-1.4-1.2-1.51.01.92.71.42.5
Condit. Reinf. active responses2.94.010.1-1.22.1-2.1-2.2-2.50.31.01.91.93.2
Condit. Reinf. inactive responses0.91.12.6-1.61.0-0.9-1.3-1.2-0.5-1.1-0.90.60.8
Condit. Reinf. lever presses2.12.97.3-1.51.7-1.6-2.1-2.20.20.20.91.92.7
Condit. Reinf. lever reinforcers received3.54.913.5-1.12.1-2.2-2.5-2.70.30.92.22.43.7
Conditioned reinforcement - actives1.22.05.9-2.42.1-1.6-1.9-1.70.8-0.0-0.2-0.60.5
Conditioned reinforcement - inactives1.32.05.0-1.72.2-1.6-1.8-1.81.20.60.2-0.70.6
Conditioned locomotion0.50.62.1-1.21.4-0.7-0.9-0.80.60.30.1-0.50.2
Patch foraging indifference point 0 sec1.01.94.32.0-2.11.61.81.7-0.50.1-0.10.6-1.2
Patch foraging indifference point AUC0.00.10.30.5-0.3-0.10.30.20.10.10.3-0.10.1
Delay disc. indifference point, 0s delay0.60.71.51.2-0.60.51.21.1-0.10.50.2-1.1-0.8
Delay disc. indifference point, 16s delay0.70.81.70.9-1.10.91.31.3-0.60.1-0.4-0.3-1.0
Delay disc. indifference point, 2s delay2.22.46.1-0.4-1.31.21.31.6-1.4-1.6-2.5-1.4-2.0
Delay disc. indifference point, 24s delay2.32.64.90.8-1.31.81.41.5-2.2-2.2-2.00.5-1.2
Delay disc. indifference point, 4s delay2.82.94.11.4-1.82.01.81.8-1.8-2.0-1.80.2-1.7
Delay disc. indifference point, 8s delay0.20.31.3-0.00.00.60.40.5-1.1-0.5-0.70.4-0.0
Indifference point function ln k0.40.72.70.2-0.40.50.70.90.2-0.1-0.9-1.2-1.6
Indifference point function log k0.40.72.70.2-0.40.50.70.90.2-0.1-0.9-1.2-1.6
Patch foraging total patch changes 0 sec0.71.33.71.9-1.71.11.41.2-0.30.30.40.8-0.7
Patch foraging total patch changes 12 sec0.60.71.81.0-1.30.90.90.8-0.8-0.8-0.40.9-0.1
Patch foraging total patch changes 18 sec0.91.43.51.8-1.91.31.00.8-0.9-1.2-0.11.3-0.4
Patch foraging total patch changes 24 sec1.32.38.51.30.4-0.9-0.2-0.61.62.72.90.51.1
Patch foraging total patch changes 6 sec1.01.55.72.4-1.30.61.31.10.71.41.40.3-0.5
Patch foraging time to switch 0 sec0.10.30.70.3-0.70.80.40.4-0.8-0.7-0.20.70.1
Patch foraging water rate 0 sec0.30.62.70.90.2-0.20.30.20.81.61.2-0.10.3
Patch foraging water rate 12 sec0.81.62.8-0.91.4-1.7-1.1-1.21.41.71.4-0.20.8
Patch foraging water rate 18 sec0.60.92.91.5-0.00.10.80.60.51.71.60.20.3
Patch foraging water rate 24 sec1.11.54.30.41.0-1.3-0.7-0.81.72.11.9-0.40.6
Patch foraging water rate 6 sec0.60.91.7-0.91.3-1.3-0.8-0.81.11.30.7-0.60.1
Seeking ratio, delayed vs. immediate footshock1.01.22.41.6-1.31.31.41.2-1.0-0.50.01.2-0.1
Distance traveled before self-admin1.31.72.51.0-1.41.51.51.6-1.3-1.4-1.3-0.3-1.4
Distance traveled after self-admin1.41.87.4-2.70.50.1-0.40.0-0.7-1.3-2.2-1.4-0.9
Extensor digitorum longus weight1.56.010.7-2.03.3-3.2-2.7-2.72.82.42.0-1.50.8
Bone: elastic displacement1.11.32.70.8-1.21.51.11.1-1.6-1.0-0.91.40.3
Bone: elastic work0.30.40.90.5-0.60.90.70.7-0.6-0.2-0.10.90.6
Bone: endosteal estimation2.76.013.8-0.12.6-2.5-1.5-1.83.43.73.5-1.11.4
Bone: endosteal perimeter5.110.824.8-1.13.8-3.7-2.1-2.34.75.03.8-2.70.8
Epididymis fat weight0.93.110.0-3.22.0-1.5-1.3-0.91.1-0.2-1.4-2.9-1.1
Delta time in closed arm before/after self-admin0.70.72.00.8-0.90.80.91.0-0.10.2-0.5-0.6-1.4
Delta time in open arm before/after self-admin2.12.17.9-0.5-0.51.51.01.2-2.8-1.9-1.80.70.4
Diff in mean of infusions in LGA sessions0.10.20.3-0.3-0.0-0.5-0.4-0.40.50.40.4-0.5-0.2
Delay discount exponential model param2.73.04.5-0.81.7-2.0-1.8-2.02.11.92.10.11.7
Extinction: sum of active levers before priming0.30.30.90.6-0.20.10.50.4-0.10.90.90.30.6
Active lever presses in extinction session 61.21.24.00.90.5-1.0-0.3-0.60.31.82.00.81.3
Bone: final force1.82.94.9-1.32.2-2.1-1.9-2.01.91.51.7-0.71.2
Bone: final moment1.93.04.7-1.12.2-2.1-1.8-1.92.11.71.9-0.71.2
Food consumed during 24 hour testing period0.81.22.7-0.81.1-1.2-0.8-0.81.71.70.8-1.00.3
Glucose1.01.64.6-0.50.9-0.6-1.5-1.6-0.5-0.90.52.12.1
Heart weight0.60.94.22.0-0.70.91.31.1-0.40.30.60.1-0.6
Delay discount hyperbolic model param2.62.95.0-0.61.7-1.9-1.7-1.92.01.92.20.21.8
Intermittent access intake day 1-15 change0.30.72.70.80.1-0.4-0.1-0.21.60.91.2-0.8-0.6
Intermittent access intake escalation0.30.62.60.20.3-0.7-0.4-0.51.60.70.8-0.8-0.5
Intermittent access intake escalation 20.70.72.61.6-0.90.60.90.70.90.51.00.0-0.6
Intermitt. access day 1 inactive lever presses1.55.710.8-2.33.0-3.3-3.1-3.21.91.71.6-0.61.5
Intermitt. access day 15 inactive lever presses1.02.03.8-1.11.6-2.0-1.8-1.91.41.01.1-0.41.0
Intermitt. access escalation Index1.92.64.7-0.51.4-1.8-1.9-2.11.21.42.01.02.2
Intermittent access day 1 total infusions0.81.33.3-1.51.8-1.2-1.5-1.50.20.30.20.11.0
Intermittent access day 15 total infusions1.01.52.5-1.51.5-1.5-1.6-1.51.40.40.3-0.80.2
Intermittent access terminal intake (last 3 days)0.40.51.4-0.70.8-0.8-0.7-0.71.20.40.2-0.8-0.4
Intermittent access total infusions1.41.73.9-2.01.9-1.5-1.7-1.51.00.3-0.0-0.70.4
Intermittent access day 1 locomotion3.03.88.8-2.63.0-2.3-2.5-2.40.91.20.7-0.61.4
Intermittent access day 15 total locomotion0.61.13.4-0.11.1-1.1-0.7-0.81.21.91.4-0.60.2
Intermittent access total locomotion1.51.84.2-1.82.0-1.6-1.5-1.41.01.10.5-0.80.4
Intermittent access standard deviation1.22.67.1-0.71.6-2.1-1.7-1.82.71.31.4-1.2-0.3
Left kidney weight0.31.43.9-2.01.6-0.9-1.0-0.80.6-0.5-1.2-1.5-0.8
Right kidney weight0.62.87.8-2.82.4-1.7-2.2-1.91.0-0.6-0.9-1.2-0.1
Cocaine induced anxiety0.50.71.7-1.11.1-0.0-0.4-0.3-1.1-0.9-0.60.61.3
Post-drug Anxiety0.40.51.8-1.00.5-0.1-0.4-0.3-0.6-0.5-0.30.71.3
Baseline Anxiety1.01.23.71.3-0.9-0.30.40.21.61.91.7-0.4-0.1
Tail length1.35.110.5-1.93.0-2.9-3.1-3.21.51.01.60.12.0
Length with tail0.73.05.6-1.42.0-2.2-1.9-1.92.41.00.7-2.2-0.6
Length without tail1.23.816.9-1.10.2-0.30.30.72.20.5-1.3-4.1-3.6
Times rat made contact with spout2.22.54.51.1-2.12.01.51.5-2.1-1.6-1.41.5-0.4
Lifetime Intake1.31.64.4-2.11.7-1.4-1.6-1.40.9-0.0-0.4-1.0-0.1
Liver weight, left4.06.615.3-3.93.5-3.0-3.0-2.72.41.30.3-2.11.2
Liver weight, right3.35.79.6-3.13.1-3.1-2.9-2.82.51.20.5-2.00.5
Locomotor activity0.20.41.2-1.0-0.1-0.3-0.5-0.4-0.2-1.1-0.90.20.0
Locomotor testing distance1.01.76.2-1.3-0.80.40.30.6-0.5-2.2-2.5-1.0-1.5
Locomotor testing rearing0.30.72.6-0.7-0.1-0.3-0.7-0.7-0.7-1.6-0.71.00.7
Locomotion in novel chamber1.31.74.8-0.6-1.10.70.50.8-0.7-2.1-2.2-0.8-1.8
Locomotion in novel chamber post-restriction0.71.12.00.4-1.11.41.11.1-1.4-1.4-1.00.5-0.6
Fecal boli incidents, locomotor time 10.50.83.50.70.6-0.2-0.2-0.40.00.91.11.11.9
Change in fecal boli incidents, locomotor task2.72.75.60.4-2.21.81.31.4-1.8-2.4-1.90.7-1.2
Time >=10cm from walls, locomotor time 12.42.65.21.9-2.32.01.91.7-1.9-1.2-0.51.3-0.1
Bouts of movement, locomotor time 14.04.612.9-0.92.3-2.1-1.4-1.52.83.62.5-1.21.7
Total resting periods, locomotor time 12.73.09.7-0.41.6-1.6-1.0-1.12.33.12.3-0.81.4
Rest time, locomotor task time 12.63.213.91.20.8-0.8-0.0-0.31.83.73.2-0.01.5
Distance moved, locomotor task time 11.42.19.8-0.6-1.00.90.10.3-1.7-3.1-2.30.8-0.5
Vertical activity count, locomotor time 10.41.05.2-0.90.30.3-0.6-0.4-0.7-2.3-1.60.2-0.4
Time >=10cm from walls, locomotor time 21.52.24.71.6-2.21.61.61.6-1.4-1.6-1.20.6-0.9
Bouts of movement, locomotor time 21.52.44.8-1.91.6-1.7-1.4-1.32.01.40.4-2.2-0.5
Total resting periods, locomotor time 21.22.14.4-1.61.4-1.6-1.3-1.12.01.60.5-2.1-0.5
Rest time, locomotor task time 20.40.51.41.0-0.50.10.40.30.71.21.1-0.1-0.1
Distance moved, locomotor task time 20.30.31.3-0.50.20.2-0.2-0.1-0.8-1.2-1.00.20.2
Vertical activity count, locomotor time 20.50.82.3-1.51.0-0.1-0.5-0.20.1-0.8-1.4-1.0-0.5
Light reinforcement 11.23.07.92.2-1.81.81.61.4-2.1-0.30.42.81.3
Light reinforcement 21.11.84.22.1-1.81.31.21.0-1.5-0.50.21.80.3
Bone: marrow area2.65.613.2-0.12.5-2.4-1.5-1.73.43.63.4-1.01.4
Bone: maximum diameter3.66.814.8-1.83.2-3.1-2.1-2.03.83.01.9-3.0-0.2
Bone: maximum force3.66.410.5-2.33.2-3.2-3.1-3.12.81.72.1-0.91.6
Bone: maximum moment3.56.29.7-2.03.1-3.1-3.0-3.02.91.92.3-0.81.7
Mean time between licks in bursts0.41.02.1-0.41.5-1.4-1.1-1.20.30.91.10.11.1
Mean num. licks in bursts0.50.81.41.0-1.01.20.90.8-1.1-0.4-0.11.10.2
Cd content in liver1.82.03.91.8-1.00.92.01.90.51.20.1-1.5-1.9
Co content in liver2.12.46.02.5-1.11.22.11.90.81.91.3-0.7-0.9
Cu content in liver1.41.73.81.4-1.51.52.02.0-0.60.4-0.4-0.4-1.5
Fe content in liver0.10.10.40.2-0.30.3-0.2-0.2-0.2-0.50.20.60.4
K content in liver1.00.93.5-0.6-0.30.40.60.80.0-0.5-1.4-1.4-1.9
Mg content in liver0.40.41.4-0.70.2-0.00.20.40.3-0.1-0.9-1.2-1.2
Mn content in liver0.40.51.20.1-0.50.70.80.9-0.6-0.7-1.1-0.2-0.9
Na content in liver0.00.00.1-0.30.3-0.1-0.00.00.20.2-0.0-0.10.2
Rb content in liver0.91.14.1-0.80.9-0.9-0.3-0.21.51.0-0.0-2.0-1.1
Se content in liver0.40.52.00.10.2-0.10.30.40.80.60.0-1.4-1.3
Sr content in liver3.83.37.32.1-2.12.32.72.7-1.0-0.1-0.9-0.4-1.7
Zn content in liver2.22.48.20.8-1.11.21.71.90.1-0.0-1.2-2.1-2.9
Bone: minimum diameter2.03.76.7-0.62.4-2.4-1.6-1.72.62.52.2-1.30.4
Time in familiar zone, hab. session 10.20.20.30.1-0.60.40.40.40.0-0.5-0.5-0.3-0.5
Time in novel zone, hab. session 10.50.51.70.40.5-0.6-0.4-0.50.20.91.30.60.9
Total zone transitions, hab. session 10.40.61.3-1.00.9-0.7-0.9-0.90.1-0.30.10.21.1
Total locomotion distance, hab. session 10.30.51.0-1.00.8-0.4-0.8-0.7-0.4-0.7-0.40.21.0
Locomotion velocity, hab. session 10.50.71.6-1.21.0-0.6-1.1-1.0-0.1-0.6-0.20.41.3
Time in familiar zone, hab. session 20.60.61.4-1.10.9-1.0-1.2-1.10.3-0.30.1-0.20.4
Time in novel zone, hab. session 21.01.03.11.7-0.30.21.00.80.81.81.2-0.5-0.4
Total zone transitions, hab. session 21.11.44.3-0.1-0.60.5-0.4-0.5-1.7-1.8-0.52.11.6
Total locomotion distance, hab. session 20.81.12.7-0.70.10.1-0.8-0.8-1.1-1.5-0.41.61.6
Locomotion velocity, hab. session 20.91.23.5-1.00.4-0.2-1.1-1.1-1.0-1.3-0.31.61.9
Novel to familiar place preference ratio1.51.74.42.1-0.50.70.90.5-0.91.01.71.81.5
Novelty place preference1.51.64.02.0-0.50.70.90.5-0.81.11.71.81.5
Time in novel zone, NPP test1.41.54.42.1-0.60.60.90.6-0.61.21.71.51.4
Total zone transitions, NPP test0.50.73.1-0.10.1-0.2-0.7-0.8-0.3-0.30.71.51.8
Total locomotion distance, NPP test0.70.93.5-0.40.3-0.2-0.9-1.0-0.5-0.60.31.71.9
Locomotion velocity, NPP test0.71.03.9-0.30.20.1-0.8-0.9-0.9-0.80.12.01.9
Intraocular pressure0.40.61.2-0.60.9-1.1-0.9-0.91.00.40.7-0.40.3
Delta distance traveled before/after self-admin2.22.310.5-3.21.7-1.3-1.9-1.60.4-0.3-0.8-0.11.0
Delta ambulatory time before/after self-admin1.82.210.2-3.21.6-1.3-1.8-1.50.5-0.4-1.0-0.60.6
Parametrial fat weight2.66.115.7-3.82.4-2.1-2.2-1.61.9-0.9-2.1-4.0-2.0
Pavlov. Cond. lever latency0.60.72.11.50.2-0.30.2-0.01.21.11.2-0.8-0.4
Pavlov. Cond. magazine entry latency0.40.61.8-1.0-0.40.50.30.5-0.8-1.0-1.3-0.3-0.7
Pavlov. Cond. change in total contacts0.20.21.7-1.30.0-0.1-0.4-0.3-0.1-0.4-0.40.10.4
Pavlov. Cond. index score0.60.81.8-1.3-0.40.4-0.10.1-1.3-1.2-1.30.80.4
Pavlov. Cond. latency score0.81.02.2-1.4-0.40.5-0.00.2-1.5-1.5-1.50.80.3
Pavlov. Cond. lever contacts0.70.81.9-1.1-0.60.60.10.3-1.4-1.3-1.30.80.2
Pavlov. Cond. magazine entry number0.50.61.81.40.2-0.30.1-0.11.11.21.3-0.4-0.0
Pavlov. Cond. intertrial magazine entries1.01.32.90.31.1-1.0-0.9-1.11.31.41.70.21.3
Pavlov. Cond. lever-magazine prob. diff.0.60.71.9-1.4-0.30.3-0.2-0.0-1.2-1.3-1.20.70.3
Pavlov. Cond. response bias0.50.62.3-1.5-0.10.2-0.3-0.1-0.9-1.1-1.30.20.1
Pavlov. Cond. lever latency1.41.96.50.8-1.10.81.31.40.80.1-0.7-2.2-2.6
Pavlov. Cond. magazine entry latency0.60.72.2-0.30.3-0.3-0.8-0.8-0.8-0.80.01.51.4
Pavlov. Cond. change in total contacts0.81.35.9-0.70.6-0.3-0.8-0.9-0.6-0.10.52.02.4
Pavlov. Cond. index score1.21.65.3-0.90.9-0.7-1.2-1.3-0.8-0.50.32.02.3
Pavlov. Cond. latency score1.21.65.1-0.90.9-0.7-1.3-1.4-0.9-0.70.22.02.3
Pavlov. Cond. lever contacts1.62.27.3-1.01.0-0.8-1.4-1.6-1.1-0.60.42.52.7
Pavlov. Cond. magazine entry number0.91.14.00.4-0.60.51.01.10.70.4-0.4-1.8-2.0
Pavlov. Cond. intertrial magazine entries0.30.41.30.8-0.30.20.80.70.41.10.7-0.2-0.3
Pavlov. Cond. lever-magazine prob. diff.1.01.34.9-0.60.9-0.6-1.1-1.2-0.8-0.40.41.92.2
Pavlov. Cond. response bias1.11.55.6-0.60.6-0.4-1.0-1.1-1.0-0.40.42.32.4
Time in closed arm before self-admin0.70.92.61.60.21.21.21.1-0.80.60.60.90.5
Time in closed arm after self-admin1.41.54.02.0-0.81.51.81.7-0.11.20.40.0-0.6
Time in open arm before self-admin3.13.46.8-2.51.2-2.6-2.6-2.42.20.20.2-1.30.0
Time in open arm after self-admin1.82.07.5-2.71.0-0.9-1.5-1.3-1.3-1.5-1.30.21.1
Bone: periosteal estimation3.37.014.3-1.53.4-3.2-2.3-2.43.83.12.5-2.10.6
Bone: periosteal perimeter4.67.916.1-1.53.6-3.3-2.2-2.34.03.62.7-2.60.5
Bone: post-yield work2.13.17.5-1.41.9-2.0-1.8-1.82.71.61.6-1.40.7
Progressive ratio test 1 active lever presses3.74.510.0-3.22.8-2.7-2.9-2.71.70.60.2-0.90.7
Progressive ratio test 1 breakpoint3.74.610.6-3.32.8-2.7-2.9-2.71.70.50.1-1.00.7
Progressive ratio test 1 inactive lever presses1.42.04.4-2.11.8-1.8-1.9-1.71.10.3-0.1-1.1-0.0
Progressive ratio test 2 active lever presses2.32.77.6-2.82.1-1.9-2.0-1.81.60.70.1-1.30.2
Progressive ratio test 2 breakpoint2.62.98.3-2.92.1-1.9-2.1-1.91.70.60.0-1.30.2
Progressive ratio test 2 inactive lever presses1.93.05.6-2.12.4-2.2-2.2-2.11.81.00.7-1.00.6
Incentive Sensitization - Responses0.30.42.1-1.40.7-0.5-0.8-0.60.3-0.4-0.4-0.40.3
Incentive Sensitization - Breakpoint0.40.52.0-1.40.8-0.5-0.9-0.70.4-0.4-0.3-0.30.4
Sum of active levers in priming session hrs 5-60.50.41.4-0.3-0.10.40.30.3-1.20.30.01.11.1
Progressive ratio0.20.30.8-0.70.1-0.20.00.10.90.8-0.1-0.8-0.5
Food seeking constrained by brief footshock1.21.43.50.8-0.70.31.21.31.41.3-0.1-1.9-1.7
Seeking ratio, punishment vs. effort0.10.10.4-0.0-0.00.10.10.1-0.2-0.5-0.6-0.2-0.2
Retroperitoneal fat weight3.715.827.8-5.05.3-5.0-4.4-4.14.42.31.1-4.10.3
Reaction time number correct2.03.97.8-0.51.7-2.2-2.1-2.31.62.02.80.82.4
Reaction time mean minus median0.51.13.5-1.91.4-0.9-1.5-1.30.5-0.6-0.30.00.7
Reaction time mean minus median AUC1.02.64.7-2.12.2-1.7-2.0-1.91.60.80.9-0.51.4
Reaction time num false alarms0.71.03.2-1.30.5-0.5-0.9-0.8-1.1-1.8-1.30.70.3
Reaction time num false alarms AUC0.91.43.8-1.40.6-0.4-1.0-0.9-1.3-1.9-1.41.10.7
Reaction time trials correct on left2.03.97.8-0.51.7-2.2-2.1-2.31.62.02.80.82.4
Reaction time trials on left2.03.87.3-0.61.7-2.2-2.1-2.41.61.92.70.82.4
Reaction time mean1.93.010.4-1.4-0.61.20.81.3-1.2-2.3-3.2-1.3-2.1
Reaction time mean AUC1.42.38.0-1.4-0.40.90.71.1-1.0-1.9-2.8-1.3-1.9
Median of all reaction times2.84.012.5-1.0-1.21.61.41.9-1.4-2.4-3.5-1.5-2.6
Reaction time omissions1.72.57.2-2.71.3-1.0-2.0-1.8-0.3-2.1-1.60.30.5
Reaction time false alarm rate1.01.45.4-0.8-0.20.5-0.00.2-1.7-2.3-2.10.6-0.3
Reaction time premature initiation rate0.30.41.0-1.00.8-0.4-0.4-0.3-0.7-0.7-0.8-0.10.4
Reaction time premature initiations0.81.43.0-1.41.7-1.5-1.4-1.40.30.40.60.11.5
Std. dev. reaction times1.12.07.6-2.81.1-0.3-1.2-0.8-0.4-2.1-2.2-0.5-0.3
Reaction time trials completed2.03.87.3-0.61.7-2.2-2.1-2.41.61.92.70.82.4
Reaction time trials AUC2.03.86.9-0.71.7-2.2-2.2-2.41.51.82.60.92.4
Run reversals in cocaine runway, females0.90.92.6-0.20.3-0.9-0.4-0.41.61.20.7-1.5-1.0
Run reversals in cocaine runway, males1.51.53.7-1.91.7-1.5-1.7-1.60.50.00.0-0.21.1
Latency to leave start box in cocaine runway0.10.10.70.5-0.80.10.50.4-0.00.10.10.1-0.2
Latency to leave start box in cocaine runway, F0.10.10.40.1-0.60.30.40.4-0.2-0.4-0.30.1-0.2
Latency to leave start box in cocaine runway, M0.10.10.10.1-0.2-0.4-0.2-0.30.00.30.40.30.3
Std. dev. time between licks in bursts3.04.16.7-0.52.5-2.4-1.8-1.92.62.62.5-1.20.9
Total sessions with >9 infusions0.70.82.5-1.61.1-0.9-1.2-1.00.2-0.7-0.7-0.3-0.5
Short access day 1 total inactive lever presses1.41.93.6-1.21.7-1.9-1.7-1.71.60.70.5-1.2-0.4
Short access day 10 total inactive lever presses0.51.22.2-1.31.1-1.5-1.4-1.50.50.70.70.31.1
Short access day 1 total infusions0.60.71.3-1.10.8-0.9-1.1-1.00.5-0.6-0.6-0.9-0.9
Short access day 10 total infusions0.40.61.8-1.00.3-0.3-0.7-0.5-0.4-1.3-1.2-0.1-0.5
Short access total infusions1.01.23.9-2.00.9-0.7-1.1-0.80.0-1.3-1.5-0.9-0.8
Short access day 1 locomotion0.20.30.7-0.90.3-0.4-0.6-0.5-0.1-0.7-0.6-0.2-0.5
Short access day 10 total locomotion0.30.51.4-0.81.2-0.8-1.0-1.00.1-0.4-0.10.00.3
Short access total locomotion1.01.24.0-2.01.4-1.2-1.5-1.30.1-0.7-0.7-0.40.0
One hour access (0.3 mA shock)1.51.73.7-1.41.9-1.4-1.9-1.91.10.30.8-0.10.8
Compulsive drug intake0.30.40.8-0.40.8-0.8-0.9-0.90.60.30.6-0.00.2
One hour access (shock baseline)0.20.20.7-0.50.8-0.5-0.6-0.60.50.10.0-0.5-0.1
Social response proportion0.80.92.6-0.1-0.60.80.70.9-0.5-0.8-1.4-1.1-1.6
Social responses0.20.30.7-0.5-0.10.30.30.4-0.2-0.1-0.8-0.8-0.7
Social time0.81.13.4-1.1-0.20.20.20.50.1-0.6-1.7-1.8-1.7
Soleus weight0.41.14.30.7-0.1-0.10.70.61.52.11.5-0.9-0.2
Bone: stiffness4.37.012.4-3.03.5-3.5-3.5-3.52.60.91.3-1.31.0
Tibialis anterior weight1.03.45.3-1.42.2-2.3-2.0-2.12.01.81.9-0.11.5
Time to tail flick, vehicle, before self-admin0.50.52.10.9-0.50.30.50.50.2-0.3-0.4-1.2-1.5
Time to tail flick, vehicle, after self-admin0.20.31.01.00.10.20.50.30.00.70.80.20.3
Time to tail flick, test, before self-admin1.91.97.22.7-0.80.91.71.4-0.31.61.60.40.5
Time to tail flick, test, after self-admin1.51.64.1-1.52.0-1.2-1.4-1.30.20.90.50.21.9
Delta time to tail flick, vehicle, before/after SA0.80.72.50.00.9-0.5-0.4-0.60.10.91.30.91.6
Delta time to tail flick, test, before/after SA2.82.911.7-3.41.8-1.3-1.9-1.50.8-0.9-1.7-1.4-0.3
Tibia length1.95.211.2-3.32.4-2.6-2.5-2.22.80.6-0.3-2.9-0.5
Ambulatory time before self-admin0.40.71.71.3-0.90.91.11.1-0.7-0.20.1-0.1-0.7
Ambulatory time after self-admin1.41.76.2-2.50.40.3-0.00.4-0.9-1.2-2.3-1.4-0.9
Bone: tissue strength1.01.02.7-0.51.0-1.0-0.5-0.51.51.61.1-0.90.5
Total heroin consumption1.82.28.51.20.5-0.60.2-0.10.42.92.71.01.5
Bone: trabecular number1.42.45.3-2.11.8-1.8-2.3-2.21.4-0.10.1-1.10.0
Bone: trabecular spacing0.81.01.81.2-1.21.41.21.0-1.1-0.40.01.10.6
Bone: trabecular thickness0.81.02.9-0.70.6-0.9-0.6-0.51.60.70.1-1.7-1.2
Bone: trabecular tissue density0.91.34.61.5-1.00.90.80.6-0.9-0.10.82.21.2
Water consumed over 24 hours0.20.20.80.3-0.60.50.50.60.1-0.2-0.5-0.3-0.9
Number of responses in last shaping day0.50.61.2-0.70.7-0.9-0.8-0.71.10.30.1-0.9-0.8