Hub : Genes

Psmb9

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	intron excision ratio	chr20_4670788_4672059	0.08	0.04	2.4e-04	0.01	0.02	0.02	0.02	9.5e-03	1.4e-03	3.3e-03	1.5e-03
2	Liver	intron excision ratio	chr20_4669110_4670721	0.07	0.04	7.9e-04	0.03	0.02	0.01	0.02	2.8e-04	2.6e-03	1.1e-02	1.3e-03
3	Adipose	mRNA stability	Psmb9	0.03	0.02	9.5e-04	0.02	0.03	0.02	0.03	5.5e-03	3.4e-04	1.3e-03	5.6e-04
4	Liver	gene expression	Psmb9	0.36	0.1	0.0e+00	0.43	0.42	0.43	0.43	2.5e-51	1.4e-50	2.0e-51	1.3e-51
5	LHb	gene expression	Psmb9	0.2	0.1	3.3e-04	0.04	0.14	0.12	0.11	4.4e-02	4.4e-04	1.2e-03	1.4e-03
6	PL	gene expression	Psmb9	0.14	0.06	1.2e-15	0.13	0.14	0.12	0.12	1.9e-14	1.2e-14	2.2e-13	1.4e-13
7	IC	gene expression	Psmb9	0.17	0.08	9.0e-06	0.09	0.1	0.07	0.09	2.0e-04	3.8e-05	4.7e-04	1.9e-04
8	BLA	gene expression	Psmb9	0.25	0.09	3.5e-12	0.2	0.22	0.19	0.22	8.5e-11	6.5e-12	2.6e-10	8.7e-12
9	NAcc	gene expression	Psmb9	0.33	0.21	0.0e+00	0.2	0.19	0.21	0.21	3.1e-30	3.8e-28	1.8e-30	1.9e-30
10	Brain	gene expression	Psmb9	0.16	0.07	5.7e-13	0.16	0.14	0.15	0.15	1.1e-14	1.9e-13	3.3e-14	3.4e-14
11	pVTA	gene expression	Psmb9	0.2	0.08	2.8e-14	0.14	0.16	0.16	0.16	1.4e-11	3.2e-13	4.5e-13	1.0e-12
12	RMTg	gene expression	Psmb9	0.15	0.09	4.3e-03	0.06	0.02	-0.01	0	1.1e-02	7.8e-02	6.3e-01	2.7e-01
13	Adipose	gene expression	Psmb9	0.12	0.06	5.0e-10	0.05	0.08	0.1	0.07	1.2e-06	3.2e-09	4.0e-11	1.5e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Bone: apparent density	0.7	1.3	5.0	1.9	1.8	-1.2	2.2	-1.4	-0.4	-0.3	-0.3	0.7	0.1	0.6	-0.2	-0.6
Area under the delay curve	0.2	0.3	0.8	-0.8	-0.6	0.7	-0.5	0.9	0.7	0.6	0.6	-0.5	-0.5	0.2	-0.5	-0.1
BMI with tail	0.3	0.9	4.1	2.0	1.2	1.5	-1.7	0.7	0.3	0.1	-0.2	-0.3	-0.3	-0.2	0.2	0.3
BMI without tail	0.6	3.0	8.1	0.4	0.4	2.8	-2.6	2.6	1.8	1.7	1.6	-1.8	-1.5	0.9	-1.2	-0.1
Body weight	0.6	2.8	16.4	-0.5	-1.1	2.7	-4.1	2.1	0.5	0.3	-0.0	-0.4	0.1	-1.2	0.5	1.9
Weight adjusted by age	0.3	1.0	4.4	-1.3	-1.1	0.9	-2.1	0.7	0.1	-0.2	-0.3	0.5	0.9	-1.0	0.4	1.2
Bone surface	0.2	0.4	0.9	-0.4	-0.5	-0.5	0.5	-0.5	-0.7	-0.6	-0.6	0.9	0.9	-0.5	0.6	0.9
Bone volume	0.1	0.2	0.9	0.7	0.6	-0.4	0.9	-0.4	-0.3	-0.2	-0.2	0.5	0.2	0.1	0.0	0.3
Breakpoint value in progressive ratio session	0.0	0.1	0.2	-0.3	-0.3	-0.4	0.4	-0.3	-0.4	-0.3	-0.2	0.1	0.1	-0.1	0.3	-0.1
Number of licking bursts	0.4	1.3	2.6	-1.6	-1.6	-1.0	0.4	-0.7	-1.3	-1.1	-1.0	0.9	1.1	-1.1	1.2	1.0
Context. condit. distance diff. score	5.8	7.0	12.9	-1.1	-1.6	-3.6	2.9	-3.3	-3.2	-3.0	-2.8	2.9	2.5	-2.2	2.5	1.4
Locomotion velocity, session 1	0.3	0.4	1.5	-1.2	-0.7	-1.1	1.2	-0.6	-0.2	-0.2	-0.1	-0.1	-0.2	0.0	0.1	-0.0
Locomotion distance, session 1	0.5	0.6	2.3	1.1	1.0	-1.0	1.5	-1.1	-0.4	-0.3	-0.2	0.2	-0.1	0.4	-0.0	-1.1
Locomotion velocity, session 2	0.2	0.2	0.6	-0.5	-0.5	-0.7	0.8	-0.4	-0.6	-0.4	-0.3	0.3	0.2	-0.2	0.4	0.2
Locomotion distance, session 2	0.9	1.2	3.1	0.7	0.3	-1.6	1.2	-1.8	-1.3	-1.3	-1.3	1.0	0.8	-0.8	0.9	0.2
Locomotion velocity, session 3	1.1	1.2	1.8	0.5	0.8	1.0	-0.2	1.1	1.2	1.3	1.3	-1.2	-1.3	1.3	-1.2	-1.3
Locomotion distance, session 3	0.5	0.5	2.2	0.8	0.8	-1.0	1.5	-0.9	-0.3	-0.1	-0.0	-0.1	-0.3	0.5	-0.2	-1.1
Stereotopy head waving bouts, day 3	0.8	1.0	3.0	-1.7	-1.6	0.6	-1.7	0.7	-0.2	-0.2	-0.3	0.2	0.9	-0.9	0.6	1.1
Stereotopy head waving duration, day 3	0.6	0.8	2.7	-1.6	-1.3	0.9	-1.6	1.2	0.5	0.4	0.4	-0.6	-0.0	-0.2	-0.1	0.5
Locomotion velocity, session 7	2.9	3.2	8.9	1.4	0.9	-2.7	2.6	-3.0	-1.8	-1.9	-1.8	1.6	1.0	-0.9	1.2	0.3
Locomotion distance, session 7	1.7	2.2	7.9	1.1	1.2	-2.6	2.8	-2.5	-1.1	-1.1	-1.0	0.9	0.4	0.0	0.3	-0.4
Stereotopy head waving bouts, day 7	2.1	2.4	6.0	-1.1	-0.4	1.3	-0.4	1.9	1.6	1.7	1.9	-2.4	-2.1	1.5	-1.4	-1.1
Stereotopy head waving duration, day 7	1.3	1.6	3.4	-0.8	-0.3	1.4	-1.0	1.8	1.4	1.4	1.5	-1.8	-1.5	1.0	-1.1	-0.9
Locomotion velocity, session 8	3.1	3.8	7.8	-2.7	-2.8	-1.9	0.8	-1.4	-2.1	-2.0	-1.8	1.7	1.7	-2.0	2.0	1.6
Locomotion distance, session 8	5.9	8.6	15.9	-0.3	-1.1	-4.0	2.9	-4.0	-3.6	-3.5	-3.3	3.3	2.7	-2.5	2.9	1.4
Degree of sensitization distance	1.1	1.2	2.4	-1.0	-1.1	-0.9	0.2	-0.9	-1.1	-1.1	-1.1	1.3	1.3	-1.2	1.1	1.5
Degree of sensitization stereotypy	1.7	1.9	4.8	-0.5	0.1	0.7	0.7	1.3	1.3	1.5	1.6	-2.2	-2.1	1.6	-1.4	-1.4
Conditioned locomotion	0.9	1.0	2.0	-0.4	-0.9	-0.0	-0.7	-0.3	-1.0	-1.0	-1.1	1.4	1.4	-1.3	1.2	1.4
Cocaine response after cond. corrected	1.6	2.4	4.0	0.6	-0.1	-1.3	0.2	-1.8	-1.9	-1.9	-2.0	1.8	1.7	-1.7	1.8	1.4
Cocaine response after cond. not corrected	0.9	1.4	2.5	-0.9	-1.2	-0.4	-0.8	-0.5	-1.2	-1.2	-1.3	1.1	1.3	-1.5	1.5	1.6
Cocaine response before conditioning	2.6	3.1	8.0	-2.4	-1.8	2.3	-2.3	2.8	1.6	1.6	1.7	-1.5	-0.9	0.6	-1.0	0.1
Saline control response	4.6	6.3	10.9	1.0	1.5	3.3	-2.2	3.1	3.1	3.0	2.8	-2.6	-2.4	2.3	-2.6	-1.4
Bone: connectivity density	1.0	1.7	3.5	1.4	1.0	-1.5	1.8	-1.9	-1.2	-1.1	-1.2	1.7	1.2	-0.5	0.7	0.2
Bone: cortical apparent density	0.9	1.4	2.7	1.6	1.4	1.7	-1.3	1.2	1.2	1.2	1.0	-0.7	-1.0	0.9	-1.0	-0.4
Bone: cortical area	0.1	0.1	0.3	-0.5	-0.6	0.4	-0.2	0.5	0.0	0.1	0.1	-0.2	-0.2	-0.1	0.1	0.4
Bone: cortical porosity	3.0	3.2	6.7	-1.5	-0.5	1.0	0.2	1.9	2.0	2.0	2.2	-2.6	-2.2	1.9	-1.9	-1.8
Bone: cortical porosity	1.7	1.9	4.2	-2.0	-1.1	0.6	0.1	1.4	1.4	1.4	1.6	-2.0	-1.5	1.2	-1.3	-1.2
Bone: cortical thickness	1.3	2.2	3.7	1.6	1.6	1.6	-0.3	1.4	1.5	1.6	1.5	-1.4	-1.9	1.6	-1.5	-1.2
Bone: cortical thickness	2.0	2.5	3.9	1.9	2.0	2.0	-1.1	1.6	1.6	1.6	1.5	-1.1	-1.6	1.5	-1.5	-1.0
Bone: cortical tissue density	0.8	1.2	2.6	1.5	1.3	1.6	-1.3	1.2	1.2	1.1	1.0	-0.6	-0.8	0.8	-0.9	-0.3
Condit. Reinf. active minus inactive responses	0.4	0.4	0.9	-0.3	0.2	-0.1	0.6	0.2	0.8	0.7	0.8	-0.6	-0.7	0.9	-1.0	-0.5
Condit. Reinf. active-inactive response ratio	1.1	1.1	1.9	0.2	0.6	1.2	-0.7	1.2	1.4	1.3	1.3	-0.9	-1.1	1.2	-1.3	-0.9
Condit. Reinf. active responses	0.2	0.2	0.6	0.4	0.8	-0.4	0.7	-0.4	0.4	0.3	0.3	-0.1	-0.3	0.6	-0.6	-0.2
Condit. Reinf. inactive responses	0.6	0.8	2.8	1.7	1.6	-1.0	1.5	-1.2	-0.2	-0.2	-0.2	0.4	-0.1	0.5	-0.2	-0.4
Incentive salience index mean	0.9	1.1	2.9	-0.7	-0.7	-1.7	1.6	-1.4	-1.1	-1.1	-0.9	1.1	0.8	-0.6	0.7	0.6
Condit. Reinf. lever presses	4.3	6.4	10.7	-0.7	-1.4	-3.3	2.3	-3.2	-3.1	-3.0	-2.9	2.8	2.4	-2.3	2.6	1.6
Condit. Reinf. active minus inactive responses	0.4	0.6	1.5	-1.1	-0.7	1.0	-0.9	1.2	0.9	0.8	0.8	-0.5	-0.4	0.3	-0.6	0.3
Condit. Reinf. active-inactive response ratio	0.4	0.7	3.2	-1.8	-1.4	0.6	-1.1	0.9	0.3	0.2	0.3	-0.1	0.1	-0.3	0.1	1.1
Condit. Reinf. active responses	0.2	0.4	0.7	-0.4	-0.1	0.6	-0.4	0.8	0.8	0.8	0.8	-0.5	-0.5	0.6	-0.7	-0.3
Condit. Reinf. inactive responses	0.4	0.6	1.0	1.0	1.0	0.6	-0.1	0.5	0.7	0.8	0.7	-0.7	-0.8	0.9	-0.8	-1.0
Condit. Reinf. lever presses	0.4	0.5	1.0	-0.2	0.2	-0.2	1.0	0.2	0.7	0.8	0.9	-0.8	-0.9	1.0	-0.9	-0.9
Condit. Reinf. lever reinforcers received	0.3	0.4	0.8	-0.6	-0.2	0.6	-0.2	0.8	0.8	0.8	0.9	-0.6	-0.7	0.7	-0.7	-0.3
Conditioned reinforcement - actives	0.0	0.1	0.4	0.6	0.6	-0.1	0.1	-0.2	0.2	0.1	0.1	-0.3	-0.2	0.3	-0.3	-0.0
Conditioned reinforcement - inactives	0.1	0.1	0.5	0.2	0.4	0.1	-0.3	0.1	0.5	0.3	0.3	-0.7	-0.5	0.3	-0.4	-0.1
Conditioned locomotion	0.1	0.1	0.3	-0.2	-0.1	-0.5	0.2	-0.5	-0.2	-0.3	-0.3	0.3	0.4	-0.3	0.1	0.4
Patch foraging indifference point 0 sec	1.3	3.7	6.8	0.7	1.1	2.6	-2.4	2.4	2.4	2.1	2.0	-2.1	-2.1	1.5	-1.8	-0.5
Patch foraging indifference point AUC	0.3	0.6	1.5	-1.0	-0.4	0.9	-0.8	1.2	0.8	0.9	1.0	-0.5	-0.5	0.6	-0.6	-0.5
Delay disc. indifference point, 0s delay	0.6	0.6	1.3	-0.8	-1.0	-0.6	0.0	-0.6	-0.8	-0.9	-0.9	0.7	0.6	-1.0	0.9	1.1
Delay disc. indifference point, 16s delay	0.6	0.8	1.3	0.4	0.6	0.9	0.0	0.9	1.1	1.1	1.1	-0.9	-0.9	1.0	-1.1	-1.0
Delay disc. indifference point, 2s delay	0.6	0.6	3.7	-1.9	-1.5	0.3	-0.9	0.6	0.2	0.1	0.1	-0.1	-0.0	-0.5	0.1	0.6
Delay disc. indifference point, 24s delay	0.9	1.5	2.6	-0.8	-0.2	1.3	-0.9	1.6	1.6	1.4	1.5	-1.4	-1.1	0.9	-1.3	-0.8
Delay disc. indifference point, 4s delay	0.8	0.9	2.3	-1.1	-0.9	1.3	-1.4	1.5	0.9	0.8	0.8	-0.9	-0.7	0.1	-0.4	0.1
Delay disc. indifference point, 8s delay	0.1	0.1	0.3	-0.4	-0.2	0.3	0.0	0.5	0.5	0.4	0.4	-0.3	-0.4	0.2	-0.4	-0.2
Indifference point function ln k	0.1	0.3	0.9	-0.9	-0.9	-0.7	0.7	-0.4	-0.6	-0.5	-0.4	0.2	0.2	-0.4	0.4	0.7
Indifference point function log k	0.1	0.3	0.9	-0.9	-0.9	-0.7	0.7	-0.4	-0.6	-0.5	-0.4	0.2	0.2	-0.4	0.4	0.7
Patch foraging total patch changes 0 sec	1.4	4.1	7.2	0.9	1.2	2.7	-2.4	2.5	2.5	2.2	2.1	-2.2	-2.2	1.6	-1.9	-0.6
Patch foraging total patch changes 12 sec	1.9	2.6	4.9	0.5	0.9	2.2	-1.9	2.1	2.0	1.9	1.8	-1.2	-1.4	1.4	-1.5	-1.1
Patch foraging total patch changes 18 sec	1.2	2.8	5.6	2.4	2.3	2.0	-1.6	1.4	1.7	1.6	1.4	-1.4	-1.5	1.5	-1.4	-1.2
Patch foraging total patch changes 24 sec	0.6	2.2	5.4	2.1	2.3	1.0	-0.1	0.7	1.5	1.4	1.3	-1.3	-1.4	1.7	-1.5	-1.4
Patch foraging total patch changes 6 sec	2.0	3.4	5.4	1.0	1.4	2.3	-1.7	2.1	2.3	2.1	1.9	-2.0	-2.1	1.6	-1.8	-1.0
Patch foraging time to switch 0 sec	0.3	1.0	4.2	2.1	1.1	-0.2	-0.2	-1.0	-0.9	-1.0	-1.2	1.1	1.0	-0.8	0.8	0.2
Patch foraging water rate 0 sec	0.1	0.2	1.5	-0.5	-0.3	0.6	-1.2	0.6	0.4	0.2	0.2	-0.2	-0.2	-0.1	-0.0	0.4
Patch foraging water rate 12 sec	0.2	0.6	1.4	1.1	1.2	0.4	0.1	0.3	0.7	0.7	0.7	-0.7	-1.2	0.9	-0.8	-0.8
Patch foraging water rate 18 sec	0.1	0.3	0.7	0.3	0.4	0.8	-0.7	0.7	0.6	0.6	0.5	-0.4	-0.4	0.3	-0.5	-0.4
Patch foraging water rate 24 sec	0.3	0.4	0.7	0.7	0.7	0.6	-0.5	0.5	0.6	0.6	0.6	-0.5	-0.8	0.6	-0.6	-0.6
Patch foraging water rate 6 sec	0.2	0.2	0.5	0.7	0.7	0.6	-0.6	0.4	0.4	0.4	0.3	-0.4	-0.5	0.4	-0.3	-0.5
Seeking ratio, delayed vs. immediate footshock	1.9	2.8	6.8	-0.4	0.0	2.3	-1.8	2.6	1.7	2.0	2.0	-1.4	-1.5	1.5	-1.4	-1.2
Distance traveled before self-admin	0.5	1.1	2.2	0.1	-0.5	-0.5	-0.3	-0.8	-1.4	-1.3	-1.3	1.5	1.3	-1.3	1.3	0.9
Distance traveled after self-admin	0.3	0.6	2.7	-0.7	-0.7	1.3	-1.6	1.3	0.3	0.4	0.4	0.1	0.1	-0.2	0.0	0.6
Extensor digitorum longus weight	0.4	1.5	2.4	-1.0	-1.3	-1.0	0.0	-0.9	-1.3	-1.3	-1.3	1.6	1.4	-1.4	1.3	1.0
Bone: elastic displacement	1.2	1.5	2.8	0.4	0.9	0.8	0.3	0.9	1.5	1.4	1.4	-1.5	-1.7	1.4	-1.5	-1.1
Bone: elastic work	0.3	0.3	0.9	-0.0	0.1	0.6	-0.1	0.7	0.7	0.6	0.6	-0.9	-1.0	0.4	-0.5	-0.2
Bone: endosteal estimation	2.0	4.8	14.2	-3.6	-3.8	0.1	-2.1	0.4	-1.3	-1.4	-1.4	1.3	2.2	-2.5	2.0	3.0
Bone: endosteal perimeter	2.1	5.2	11.0	-2.9	-3.3	-1.3	-0.4	-1.1	-2.3	-2.2	-2.2	1.8	2.5	-2.7	2.5	2.7
Epididymis fat weight	1.9	9.7	37.6	6.1	5.3	3.3	-1.9	1.8	2.6	2.4	1.9	-2.3	-2.7	2.4	-2.2	-1.6
Delta time in closed arm before/after self-admin	0.5	0.4	1.4	-0.2	-0.5	-0.1	-0.6	-0.4	-0.6	-0.7	-0.8	0.2	0.1	-1.0	0.9	1.2
Delta time in open arm before/after self-admin	0.3	0.3	0.8	0.5	0.7	0.4	0.1	0.4	0.7	0.7	0.7	-0.2	-0.4	0.8	-0.9	-0.4
Diff in mean of infusions in LGA sessions	1.1	1.9	4.0	0.6	0.1	-1.9	1.7	-2.0	-1.7	-1.5	-1.5	1.6	1.5	-0.9	1.1	0.3
Delay discount exponential model param	0.4	0.5	1.2	0.9	0.6	-0.8	0.6	-1.1	-0.9	-0.7	-0.8	0.8	0.7	-0.3	0.6	0.2
Extinction: sum of active levers before priming	0.6	0.9	1.3	-0.9	-1.0	-1.0	0.3	-1.0	-1.1	-1.1	-1.1	0.8	1.1	-1.0	1.0	0.8
Active lever presses in extinction session 6	0.2	0.2	0.5	0.7	0.7	-0.3	0.5	-0.5	0.2	0.0	0.0	-0.4	-0.5	0.2	-0.2	-0.4
Bone: final force	0.5	0.7	3.8	0.8	0.5	1.6	-2.0	1.1	0.5	0.4	0.2	-0.3	-0.4	-0.2	-0.1	0.5
Bone: final moment	0.4	0.6	2.8	0.7	0.4	1.4	-1.7	1.0	0.6	0.4	0.3	-0.4	-0.4	-0.1	-0.1	0.4
Food consumed during 24 hour testing period	0.8	1.6	3.2	-0.4	-1.0	-0.4	-0.9	-0.7	-1.4	-1.4	-1.6	1.2	1.5	-1.8	1.7	1.6
Glucose	4.3	6.8	13.4	-3.7	-3.6	-2.6	0.3	-2.1	-2.5	-2.7	-2.5	2.2	2.8	-2.8	2.6	2.2
Heart weight	0.9	1.5	3.3	-1.8	-1.2	1.5	-1.6	1.8	1.3	1.0	1.0	-1.0	-0.6	0.2	-0.7	0.7
Delay discount hyperbolic model param	0.5	0.7	1.4	1.1	0.7	-0.9	0.6	-1.2	-0.9	-0.8	-0.9	0.8	0.8	-0.4	0.7	0.2
Intermittent access intake day 1-15 change	0.1	0.3	0.7	-0.2	-0.0	0.7	-0.3	0.8	0.5	0.6	0.7	-0.8	-0.5	0.6	-0.5	-0.2
Intermittent access intake escalation	0.3	1.8	2.9	0.4	0.7	1.4	-0.5	1.6	1.5	1.6	1.6	-1.7	-1.5	1.5	-1.4	-1.0
Intermittent access intake escalation 2	0.1	0.2	0.6	-0.6	-0.3	0.3	0.2	0.5	0.4	0.4	0.5	-0.8	-0.5	0.4	-0.3	-0.1
Intermitt. access day 1 inactive lever presses	0.2	2.5	4.1	-1.3	-1.7	-1.1	-0.5	-1.1	-1.9	-1.8	-1.8	1.2	1.5	-1.9	2.0	2.0
Intermitt. access day 15 inactive lever presses	0.0	0.1	0.8	-0.4	-0.4	0.3	-0.9	0.3	-0.0	-0.1	-0.1	-0.2	0.1	-0.3	0.2	0.6
Intermitt. access escalation Index	0.6	1.9	3.4	0.1	-0.4	-1.7	1.5	-1.7	-1.8	-1.6	-1.5	1.8	1.2	-1.0	1.4	0.6
Intermittent access day 1 total infusions	0.2	0.6	2.6	0.3	0.6	-1.5	1.6	-1.4	-0.1	-0.4	-0.3	0.2	-0.1	0.1	-0.2	-0.4
Intermittent access day 15 total infusions	0.4	0.9	1.5	0.6	1.0	0.2	0.5	0.3	1.1	1.0	1.0	-1.1	-1.2	1.2	-1.2	-1.0
Intermittent access terminal intake (last 3 days)	0.5	0.8	1.5	0.2	0.7	0.3	0.1	0.5	1.2	1.0	1.1	-1.1	-1.2	1.1	-1.2	-0.8
Intermittent access total infusions	0.4	0.5	0.9	0.4	0.8	-0.2	0.6	-0.1	0.9	0.7	0.7	-0.7	-0.9	0.9	-0.9	-0.8
Intermittent access day 1 locomotion	0.1	0.2	0.6	0.8	0.8	-0.5	0.4	-0.6	0.1	-0.1	-0.1	0.2	0.0	0.2	-0.2	-0.3
Intermittent access day 15 total locomotion	0.1	0.3	1.0	0.1	0.1	0.9	-1.0	0.7	0.6	0.5	0.4	-0.2	-0.2	0.1	-0.4	-0.1
Intermittent access total locomotion	0.3	0.4	0.7	0.6	0.7	0.6	-0.2	0.5	0.9	0.7	0.7	-0.5	-0.5	0.6	-0.8	-0.6
Intermittent access standard deviation	0.3	1.7	4.1	0.5	0.6	1.9	-2.0	1.7	1.5	1.3	1.2	-1.6	-1.1	0.8	-1.1	-0.1
Left kidney weight	0.4	3.2	12.0	0.3	-0.1	3.4	-3.5	2.9	1.6	1.5	1.3	-1.4	-1.0	0.3	-0.8	0.3
Right kidney weight	0.3	2.2	12.5	0.4	-0.2	2.9	-3.5	2.2	0.9	0.8	0.5	-0.7	-0.3	-0.4	-0.2	0.9
Cocaine induced anxiety	0.3	0.9	1.8	-0.3	-0.6	-0.7	-0.0	-0.7	-1.3	-1.1	-1.1	1.3	1.2	-1.0	1.2	0.8
Post-drug Anxiety	0.2	0.2	0.5	-0.3	-0.5	0.1	-0.5	0.0	-0.6	-0.5	-0.5	0.5	0.7	-0.6	0.6	0.5
Baseline Anxiety	0.1	0.2	0.5	-0.2	-0.0	0.6	-0.5	0.6	0.5	0.5	0.4	-0.7	-0.2	0.2	-0.4	0.2
Tail length	0.8	4.3	15.2	-3.9	-3.3	2.1	-3.3	2.7	0.9	0.9	0.9	-1.0	-0.2	-0.6	-0.1	1.7
Length with tail	1.1	4.7	14.5	-3.6	-3.5	2.0	-3.8	2.2	0.2	-0.1	-0.1	-0.1	0.8	-1.7	0.8	2.9
Length without tail	0.9	4.5	11.6	-1.3	-2.2	0.8	-3.1	0.1	-1.4	-1.7	-2.0	1.7	2.1	-3.0	2.3	3.4
Times rat made contact with spout	2.9	3.4	5.2	1.4	1.9	1.0	0.5	1.2	1.9	2.0	2.0	-2.0	-2.2	2.3	-2.2	-2.3
Lifetime Intake	0.3	0.4	0.7	0.3	0.7	-0.1	0.3	-0.1	0.8	0.6	0.6	-0.6	-0.8	0.7	-0.8	-0.7
Liver weight, left	1.6	2.8	6.1	-2.1	-2.5	-0.2	-1.6	-0.2	-1.5	-1.5	-1.5	1.5	1.9	-2.1	1.9	1.6
Liver weight, right	2.2	3.9	8.6	-2.8	-2.9	-0.6	-1.2	-0.4	-1.6	-1.7	-1.7	1.6	2.1	-2.3	1.9	2.8
Locomotor activity	0.8	1.3	3.3	-1.6	-1.4	1.4	-1.6	1.8	0.7	0.9	1.0	-0.8	-0.7	0.3	-0.5	-0.5
Locomotor testing distance	0.2	0.4	1.5	-1.0	-1.2	0.7	-1.2	0.8	-0.1	0.1	0.1	0.1	0.0	-0.3	0.1	-0.0
Locomotor testing rearing	0.2	0.6	2.0	-0.7	-1.1	0.4	-1.4	0.3	-0.6	-0.6	-0.6	0.5	0.6	-1.0	0.7	0.9
Locomotion in novel chamber	0.1	0.1	0.2	0.4	0.3	0.4	0.2	0.3	0.2	0.3	0.2	-0.1	-0.2	0.2	-0.2	-0.4
Locomotion in novel chamber post-restriction	0.1	0.4	1.8	0.4	0.3	1.1	-1.3	0.8	0.6	0.4	0.3	-0.0	-0.3	0.1	-0.4	0.1
Fecal boli incidents, locomotor time 1	0.2	0.6	1.9	0.7	0.5	-1.2	0.8	-1.4	-0.8	-0.9	-0.9	0.4	0.6	-0.5	0.6	0.5
Change in fecal boli incidents, locomotor task	1.0	1.1	3.2	-1.7	-1.8	0.4	-1.5	0.5	-0.5	-0.5	-0.5	0.8	0.9	-1.1	0.9	1.2
Time >=10cm from walls, locomotor time 1	2.0	2.4	4.7	-0.8	-1.5	0.2	-2.2	-0.2	-1.4	-1.5	-1.6	1.8	1.7	-2.1	1.9	1.8
Bouts of movement, locomotor time 1	0.1	0.1	0.6	0.1	0.1	-0.2	0.7	-0.1	-0.1	0.1	0.2	-0.1	-0.2	0.3	-0.2	-0.3
Total resting periods, locomotor time 1	0.0	0.1	0.4	-0.1	-0.1	-0.4	0.6	-0.2	-0.2	-0.1	0.0	0.1	0.1	0.1	-0.0	-0.1
Rest time, locomotor task time 1	0.1	0.2	0.5	-0.7	-0.6	-0.5	0.6	-0.2	-0.4	-0.3	-0.2	-0.3	-0.2	-0.3	0.3	0.5
Distance moved, locomotor task time 1	0.1	0.3	1.3	0.1	0.1	0.9	-1.2	0.8	0.5	0.5	0.4	0.1	0.1	0.1	-0.3	-0.3
Vertical activity count, locomotor time 1	0.1	0.7	2.8	0.7	0.6	1.4	-1.7	1.0	0.9	0.7	0.5	0.0	-0.1	0.2	-0.5	-0.5
Time >=10cm from walls, locomotor time 2	0.4	1.2	4.8	-1.4	-1.5	0.6	-2.2	0.4	-0.3	-0.6	-0.6	0.6	1.2	-1.4	0.8	1.0
Bouts of movement, locomotor time 2	0.2	0.6	1.2	-0.7	-0.3	0.8	-0.3	1.1	0.8	0.9	1.0	-0.7	-0.8	0.7	-0.8	-0.6
Total resting periods, locomotor time 2	0.1	0.5	1.5	-1.2	-0.7	0.5	0.1	1.0	0.6	0.8	0.9	-0.6	-0.7	0.6	-0.7	-0.5
Rest time, locomotor task time 2	1.6	2.7	4.3	-0.9	-1.4	-1.5	0.7	-1.5	-2.1	-1.9	-1.9	1.6	1.6	-1.8	2.0	1.7
Distance moved, locomotor task time 2	0.5	0.6	1.2	0.9	0.9	1.1	-1.1	0.7	1.0	0.8	0.6	-0.3	-0.2	0.4	-0.8	-0.8
Vertical activity count, locomotor time 2	0.2	0.4	1.6	0.5	0.4	1.0	-1.3	0.6	0.8	0.5	0.4	-0.2	0.0	0.1	-0.5	-0.4
Light reinforcement 1	0.1	0.6	1.9	0.9	0.1	0.4	-1.4	-0.1	-0.7	-0.7	-0.8	0.9	1.0	-0.9	0.8	0.4
Light reinforcement 2	0.4	1.0	2.1	0.2	-0.4	-0.3	-0.9	-0.7	-1.2	-1.2	-1.4	0.7	1.0	-1.5	1.4	1.0
Bone: marrow area	1.9	4.7	13.8	-3.5	-3.7	0.3	-2.2	0.5	-1.2	-1.3	-1.3	1.2	2.1	-2.4	1.9	2.9
Bone: maximum diameter	1.3	2.7	6.0	-2.3	-2.4	-1.3	0.5	-0.9	-1.6	-1.6	-1.5	1.3	1.7	-1.7	1.6	1.8
Bone: maximum force	0.2	0.3	1.9	0.3	0.1	1.0	-1.4	0.6	0.2	0.1	-0.1	-0.0	-0.1	-0.4	0.2	0.7
Bone: maximum moment	0.1	0.2	1.2	0.1	-0.1	0.7	-1.1	0.5	0.2	0.0	-0.1	-0.1	-0.0	-0.4	0.2	0.7
Mean time between licks in bursts	0.5	2.8	5.2	-2.3	-2.2	-1.8	0.9	-1.3	-1.8	-1.6	-1.5	1.6	1.8	-1.5	1.6	1.4
Mean num. licks in bursts	1.5	4.0	5.8	2.1	2.4	1.6	-0.2	1.4	2.3	2.1	2.1	-1.9	-2.2	2.2	-2.3	-2.2
Cd content in liver	1.1	1.2	2.6	1.5	1.1	-0.9	0.2	-1.6	-0.8	-1.1	-1.3	1.3	1.2	-0.9	1.0	0.1
Co content in liver	0.4	0.4	2.2	1.0	0.8	1.0	-1.5	0.4	0.4	0.2	0.0	-0.0	0.0	-0.1	-0.1	-0.2
Cu content in liver	1.7	2.0	4.5	1.7	2.1	0.6	0.7	0.6	1.3	1.4	1.4	-1.0	-1.4	1.8	-1.6	-1.8
Fe content in liver	0.3	0.4	1.5	1.2	1.2	0.7	-0.5	0.4	0.5	0.5	0.4	-0.4	-0.4	0.4	-0.4	-0.4
K content in liver	0.6	0.6	1.3	0.3	0.2	-1.1	1.1	-1.1	-0.9	-0.7	-0.7	0.8	0.6	-0.3	0.6	-0.8
Mg content in liver	2.4	2.7	4.3	-1.1	-1.6	-1.9	1.1	-1.7	-2.1	-1.8	-1.7	2.1	1.7	-1.5	1.7	0.4
Mn content in liver	4.9	5.5	8.1	-1.8	-2.5	-2.1	0.5	-2.0	-2.7	-2.6	-2.5	2.8	2.7	-2.6	2.5	1.9
Na content in liver	0.9	1.0	2.2	0.5	0.8	0.8	0.0	1.0	0.9	1.1	1.2	-1.1	-1.2	1.2	-1.0	-1.5
Rb content in liver	0.9	1.0	2.0	0.3	0.0	-1.2	0.5	-1.4	-1.1	-1.2	-1.2	1.4	1.1	-1.0	1.0	0.6
Se content in liver	1.2	1.4	6.4	-2.5	-2.3	-1.1	0.4	-0.5	-1.0	-0.9	-0.6	0.6	0.8	-0.9	0.9	0.5
Sr content in liver	0.5	0.5	0.9	-0.6	-0.8	-0.6	-0.1	-0.6	-0.7	-0.8	-0.8	0.5	0.8	-0.9	0.9	0.1
Zn content in liver	0.8	1.0	2.2	-0.5	-0.6	-0.9	-0.1	-1.0	-1.0	-1.1	-1.1	1.4	1.5	-1.1	1.0	0.6
Bone: minimum diameter	1.7	3.3	7.0	-2.3	-2.7	-0.8	-0.4	-0.7	-1.8	-1.7	-1.7	1.5	1.9	-2.2	2.0	2.4
Time in familiar zone, hab. session 1	2.6	2.9	5.8	2.0	2.4	0.2	1.6	0.3	1.5	1.5	1.6	-1.3	-1.6	2.2	-2.0	-2.2
Time in novel zone, hab. session 1	1.4	1.6	4.1	-1.8	-2.0	0.3	-1.7	0.3	-0.8	-0.9	-0.9	0.7	1.0	-1.5	1.3	1.5
Total zone transitions, hab. session 1	0.2	0.2	0.9	0.1	-0.0	-0.8	0.9	-0.6	-0.6	-0.4	-0.4	0.3	0.0	-0.0	0.3	-0.7
Total locomotion distance, hab. session 1	0.4	0.5	1.4	0.4	0.1	-1.0	1.2	-1.0	-0.9	-0.7	-0.7	0.7	0.4	-0.3	0.5	-0.4
Locomotion velocity, hab. session 1	0.2	0.2	0.8	0.2	0.0	-0.7	0.9	-0.6	-0.6	-0.4	-0.4	0.4	0.1	-0.1	0.3	-0.5
Time in familiar zone, hab. session 2	1.0	1.2	2.1	1.2	1.2	1.1	-0.5	1.0	0.9	1.2	1.1	-0.6	-0.9	1.3	-1.1	-1.5
Time in novel zone, hab. session 2	0.1	0.1	0.6	-0.8	-0.6	-0.1	-0.3	-0.0	0.2	-0.1	-0.1	-0.4	0.1	-0.4	0.1	0.7
Total zone transitions, hab. session 2	0.4	0.5	1.1	0.8	0.2	-0.5	0.3	-0.7	-1.0	-0.7	-0.8	1.1	0.7	-0.5	0.7	-0.0
Total locomotion distance, hab. session 2	1.1	1.5	2.8	1.2	0.5	-1.4	1.2	-1.7	-1.6	-1.4	-1.4	1.6	1.0	-0.7	1.1	0.0
Locomotion velocity, hab. session 2	1.4	1.9	3.6	1.0	0.3	-1.7	1.5	-1.9	-1.8	-1.6	-1.5	1.7	1.1	-0.9	1.3	0.1
Novel to familiar place preference ratio	0.1	0.1	0.2	-0.3	0.0	-0.2	0.1	0.0	0.3	0.2	0.3	-0.5	-0.3	0.3	-0.3	-0.1
Novelty place preference	0.1	0.1	0.4	-0.6	-0.2	0.0	-0.1	0.3	0.5	0.4	0.4	-0.6	-0.4	0.3	-0.4	-0.1
Time in novel zone, NPP test	0.2	0.2	0.5	-0.7	-0.2	0.2	-0.1	0.5	0.6	0.5	0.6	-0.7	-0.5	0.4	-0.6	-0.1
Total zone transitions, NPP test	1.1	1.7	4.0	0.6	0.2	-1.9	1.9	-2.0	-1.5	-1.4	-1.3	1.2	0.9	-0.6	1.0	-0.2
Total locomotion distance, NPP test	1.9	2.6	6.4	1.3	0.6	-2.2	1.9	-2.5	-1.8	-1.8	-1.8	1.7	1.3	-1.1	1.3	0.2
Locomotion velocity, NPP test	2.4	3.5	8.6	1.5	0.7	-2.6	2.2	-2.9	-2.1	-2.1	-2.1	1.9	1.4	-1.2	1.6	0.1
Intraocular pressure	0.3	0.5	2.0	1.4	1.4	-0.0	0.4	-0.3	0.3	0.3	0.3	-0.0	0.1	0.7	-0.6	-0.9
Delta distance traveled before/after self-admin	2.3	2.5	5.6	-1.1	-0.4	2.0	-1.4	2.4	1.9	1.9	2.0	-1.7	-1.3	1.3	-1.5	-0.3
Delta ambulatory time before/after self-admin	1.1	1.9	4.8	-1.3	-0.6	1.8	-1.5	2.2	1.6	1.6	1.6	-1.3	-0.9	0.9	-1.2	-0.1
Parametrial fat weight	0.4	0.9	5.4	2.3	1.4	1.1	-1.5	0.3	-0.0	-0.1	-0.3	0.3	0.1	-0.2	0.3	0.3
Pavlov. Cond. lever latency	2.8	3.5	8.7	2.1	2.0	2.9	-2.8	2.2	1.9	1.8	1.5	-1.1	-1.0	1.1	-1.4	-0.9
Pavlov. Cond. magazine entry latency	0.6	0.8	4.0	-2.0	-1.4	-1.1	1.7	-0.3	-0.3	-0.1	0.2	-0.1	-0.1	0.1	-0.0	0.0
Pavlov. Cond. change in total contacts	0.4	0.4	2.8	-1.7	-1.2	-0.6	0.7	-0.0	-0.1	-0.1	0.1	-0.2	-0.2	-0.0	0.0	0.6
Pavlov. Cond. index score	1.9	2.4	6.2	-2.2	-2.0	-2.3	2.5	-1.5	-1.4	-1.3	-1.0	0.8	0.7	-0.8	1.0	0.8
Pavlov. Cond. latency score	2.0	2.6	6.6	-2.3	-2.1	-2.4	2.6	-1.6	-1.5	-1.3	-1.0	0.8	0.7	-0.9	1.1	0.9
Pavlov. Cond. lever contacts	3.6	4.4	8.9	-1.9	-2.0	-3.0	2.4	-2.5	-2.3	-2.3	-2.0	1.6	1.4	-1.7	2.0	1.4
Pavlov. Cond. magazine entry number	0.4	0.6	2.5	1.6	1.1	1.0	-1.5	0.3	0.4	0.2	-0.0	-0.0	-0.1	-0.1	-0.0	-0.1
Pavlov. Cond. intertrial magazine entries	0.7	0.9	4.6	2.1	2.0	0.3	-0.5	-0.2	0.6	0.4	0.2	-0.3	-0.4	0.6	-0.6	-0.8
Pavlov. Cond. lever-magazine prob. diff.	1.8	2.2	6.5	-2.1	-1.8	-2.3	2.5	-1.5	-1.4	-1.3	-1.0	0.7	0.6	-0.8	1.0	0.8
Pavlov. Cond. response bias	1.2	1.5	3.5	-1.8	-1.6	-1.9	1.9	-1.2	-1.2	-1.0	-0.8	0.7	0.7	-0.7	0.8	0.7
Pavlov. Cond. lever latency	1.0	1.5	2.4	-0.7	-1.0	-0.5	-0.7	-0.7	-1.3	-1.3	-1.4	1.3	1.5	-1.5	1.4	1.5
Pavlov. Cond. magazine entry latency	0.2	0.2	0.6	-0.7	-0.4	-0.8	0.7	-0.6	-0.4	-0.4	-0.4	0.2	0.3	-0.3	0.3	0.3
Pavlov. Cond. change in total contacts	0.5	1.3	2.3	-0.1	0.4	0.7	0.4	1.1	1.3	1.4	1.4	-1.3	-1.5	1.4	-1.3	-1.2
Pavlov. Cond. index score	0.2	0.4	0.6	-0.2	0.2	0.0	0.8	0.3	0.7	0.6	0.7	-0.7	-0.7	0.8	-0.7	-0.7
Pavlov. Cond. latency score	0.3	0.4	0.7	-0.2	0.2	0.2	0.6	0.5	0.8	0.7	0.8	-0.7	-0.8	0.8	-0.8	-0.7
Pavlov. Cond. lever contacts	0.8	1.2	2.1	0.6	0.9	0.5	0.6	0.7	1.2	1.2	1.3	-1.2	-1.4	1.4	-1.3	-1.4
Pavlov. Cond. magazine entry number	0.0	0.1	0.2	0.1	-0.0	0.4	-0.4	0.4	0.2	0.2	0.2	-0.0	-0.0	0.2	-0.1	-0.2
Pavlov. Cond. intertrial magazine entries	0.1	0.3	1.0	-1.0	-1.0	-0.5	0.2	-0.1	-0.6	-0.3	-0.2	0.6	0.6	-0.2	0.3	0.4
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.5	-0.2	0.2	0.0	0.7	0.3	0.6	0.6	0.7	-0.6	-0.7	0.7	-0.7	-0.6
Pavlov. Cond. response bias	0.3	0.4	1.0	0.1	0.4	-0.2	1.0	0.1	0.6	0.6	0.7	-0.7	-0.9	0.8	-0.7	-0.9
Time in closed arm before self-admin	0.1	0.1	0.7	-0.8	-0.6	0.0	0.0	0.2	-0.1	-0.0	-0.0	0.1	0.4	-0.2	0.0	0.1
Time in closed arm after self-admin	0.1	0.1	0.3	-0.2	-0.3	-0.3	0.2	-0.4	-0.4	-0.5	-0.5	-0.1	-0.1	-0.5	0.5	0.4
Time in open arm before self-admin	0.2	0.3	0.7	-0.7	-0.2	-0.3	0.7	0.1	0.4	0.4	0.6	-0.8	-0.7	0.6	-0.4	-0.5
Time in open arm after self-admin	0.3	0.3	0.7	-0.4	0.1	0.2	0.3	0.5	0.7	0.8	0.8	-0.5	-0.6	0.8	-0.8	-0.3
Bone: periosteal estimation	0.9	2.0	6.7	-2.4	-2.6	0.6	-1.6	0.8	-0.6	-0.6	-0.6	0.5	1.1	-1.5	1.1	2.1
Bone: periosteal perimeter	0.6	1.2	4.7	-2.1	-2.2	-0.2	-0.5	0.1	-0.8	-0.8	-0.7	0.2	0.7	-1.2	1.0	1.3
Bone: post-yield work	1.7	3.0	4.4	-1.5	-2.0	-1.3	-0.1	-1.3	-1.9	-1.9	-1.9	1.6	1.8	-2.1	2.0	1.9
Progressive ratio test 1 active lever presses	0.0	0.1	0.3	-0.1	0.1	-0.6	0.3	-0.6	-0.0	-0.2	-0.2	0.0	0.2	-0.2	-0.0	0.1
Progressive ratio test 1 breakpoint	0.0	0.1	0.3	-0.2	0.0	-0.6	0.3	-0.6	-0.0	-0.2	-0.2	0.1	0.2	-0.2	0.0	0.2
Progressive ratio test 1 inactive lever presses	0.1	0.3	1.6	1.3	0.9	-0.2	-0.1	-0.6	-0.2	-0.3	-0.4	0.4	0.2	-0.1	0.1	0.2
Progressive ratio test 2 active lever presses	0.1	0.2	0.6	0.6	0.7	-0.5	0.8	-0.5	0.1	0.0	0.1	-0.3	-0.2	0.4	-0.3	-0.4
Progressive ratio test 2 breakpoint	0.2	0.3	0.7	0.6	0.8	-0.4	0.8	-0.4	0.2	0.2	0.2	-0.5	-0.3	0.5	-0.5	-0.6
Progressive ratio test 2 inactive lever presses	0.3	0.8	1.9	-0.7	-0.6	-1.4	0.7	-1.3	-0.9	-1.0	-1.0	0.6	0.8	-0.8	0.8	0.9
Incentive Sensitization - Responses	0.0	0.1	0.5	0.1	0.2	-0.4	0.7	-0.2	-0.1	0.1	0.2	-0.4	-0.2	0.4	-0.2	-0.4
Incentive Sensitization - Breakpoint	0.1	0.1	0.6	0.4	0.4	-0.4	0.8	-0.3	-0.0	0.1	0.2	-0.4	-0.2	0.5	-0.2	-0.5
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.7	-0.8	-0.6	-0.4	0.3	-0.1	0.0	-0.0	0.0	-0.1	-0.0	-0.0	0.1	-0.2
Progressive ratio	1.2	3.4	10.1	0.6	0.5	3.2	-2.8	2.9	1.9	1.9	1.7	-1.7	-1.4	1.0	-1.2	-0.8
Food seeking constrained by brief footshock	0.6	0.7	2.2	0.4	0.5	0.5	0.1	0.6	1.0	0.9	0.9	-1.5	-1.2	0.8	-0.9	-0.7
Seeking ratio, punishment vs. effort	0.5	1.2	4.5	-0.9	-0.6	-2.1	2.1	-1.7	-0.9	-0.9	-0.7	0.4	0.4	-0.3	0.5	0.3
Retroperitoneal fat weight	0.1	0.5	1.7	1.3	0.8	-0.3	-0.3	-0.8	-0.7	-0.7	-0.9	0.5	0.5	-0.6	0.6	1.0
Reaction time number correct	0.4	1.5	2.4	1.3	1.3	1.6	-1.3	1.3	1.4	1.3	1.2	-1.4	-1.2	1.1	-1.1	-0.8
Reaction time mean minus median	0.3	1.9	3.9	-1.2	-1.2	-2.0	1.6	-1.6	-1.5	-1.4	-1.2	1.6	1.5	-1.0	1.2	0.1
Reaction time mean minus median AUC	0.4	2.5	6.2	-1.1	-1.0	-2.5	1.9	-2.2	-1.6	-1.7	-1.5	1.8	1.6	-1.1	1.2	0.3
Reaction time num false alarms	0.1	0.3	1.2	-1.1	-1.0	-0.0	-0.3	0.3	-0.3	-0.2	-0.1	0.2	0.1	-0.3	0.3	0.7
Reaction time num false alarms AUC	0.2	0.4	2.1	-1.5	-1.2	0.4	-0.6	0.8	-0.1	0.2	0.3	-0.1	-0.0	-0.1	0.1	0.5
Reaction time trials correct on left	0.4	1.5	2.4	1.3	1.3	1.6	-1.3	1.3	1.4	1.3	1.2	-1.4	-1.2	1.1	-1.1	-0.8
Reaction time trials on left	0.4	1.5	2.3	1.2	1.2	1.5	-1.3	1.2	1.3	1.3	1.1	-1.4	-1.1	1.1	-1.0	-0.8
Reaction time mean	2.2	4.8	7.1	-1.2	-1.7	-2.7	1.6	-2.6	-2.5	-2.5	-2.4	2.2	2.3	-2.2	2.2	1.7
Reaction time mean AUC	1.7	4.2	6.6	-1.1	-1.5	-2.6	1.6	-2.5	-2.3	-2.4	-2.3	2.0	2.1	-2.1	2.0	1.6
Median of all reaction times	2.6	4.1	5.7	-0.9	-1.4	-2.3	1.3	-2.4	-2.3	-2.4	-2.3	2.0	2.1	-2.2	2.1	1.9
Reaction time omissions	1.6	2.6	3.9	-0.9	-1.3	-1.9	1.2	-1.8	-2.0	-1.9	-1.8	1.8	1.9	-1.5	1.6	1.0
Reaction time false alarm rate	0.7	0.9	4.6	-2.1	-1.9	-0.6	0.2	-0.0	-0.8	-0.6	-0.4	0.7	0.6	-0.7	0.6	1.0
Reaction time premature initiation rate	0.0	0.1	0.2	0.0	-0.2	0.1	-0.1	-0.1	-0.2	-0.2	-0.3	0.3	0.4	-0.4	0.2	0.4
Reaction time premature initiations	0.1	0.4	1.3	0.7	0.5	1.1	-1.0	0.8	0.7	0.6	0.5	-0.6	-0.3	0.3	-0.5	-0.1
Std. dev. reaction times	0.7	2.4	4.0	-2.0	-1.9	-2.0	1.4	-1.5	-1.6	-1.5	-1.3	1.5	1.6	-1.3	1.3	0.8
Reaction time trials completed	0.4	1.5	2.3	1.2	1.2	1.5	-1.3	1.2	1.3	1.3	1.1	-1.4	-1.1	1.1	-1.0	-0.8
Reaction time trials AUC	0.4	1.2	2.0	1.2	1.2	1.4	-1.3	1.1	1.2	1.1	1.0	-1.2	-1.0	0.9	-0.9	-0.7
Run reversals in cocaine runway, females	0.2	0.2	1.1	1.0	0.9	0.1	0.2	-0.1	0.4	0.3	0.2	-0.0	-0.4	0.4	-0.5	-0.4
Run reversals in cocaine runway, males	0.5	0.5	1.0	-0.7	-0.7	-1.0	1.0	-0.8	-0.8	-0.7	-0.6	0.6	0.5	-0.6	0.6	0.4
Latency to leave start box in cocaine runway	1.5	2.0	2.9	-0.7	-1.0	-1.6	0.9	-1.6	-1.7	-1.7	-1.7	1.3	1.4	-1.5	1.6	1.4
Latency to leave start box in cocaine runway, F	1.1	1.3	2.3	-0.4	-0.6	-1.5	0.7	-1.5	-1.3	-1.4	-1.4	1.0	1.2	-1.1	1.2	1.0
Latency to leave start box in cocaine runway, M	0.6	0.6	0.9	-0.4	-0.7	-0.5	0.4	-0.5	-0.9	-0.9	-0.9	0.9	0.6	-1.0	0.9	0.9
Std. dev. time between licks in bursts	2.1	4.0	8.6	-2.9	-2.9	-1.5	0.7	-1.0	-2.0	-1.8	-1.7	2.0	2.2	-2.0	2.0	2.1
Total sessions with >9 infusions	0.5	0.6	1.3	-0.2	0.4	0.3	-0.3	0.5	1.1	0.9	1.0	-0.9	-0.9	0.9	-1.0	-0.7
Short access day 1 total inactive lever presses	0.3	0.7	1.3	-1.1	-0.9	-1.2	0.1	-1.0	-0.7	-0.9	-0.8	0.5	0.4	-0.9	0.7	0.9
Short access day 10 total inactive lever presses	0.1	0.7	1.7	0.3	-0.3	-0.7	-0.0	-0.8	-1.3	-1.0	-1.1	0.8	0.7	-0.8	1.1	0.7
Short access day 1 total infusions	0.0	0.1	0.4	-0.6	-0.1	-0.6	0.2	-0.5	0.2	-0.0	0.1	-0.1	-0.0	0.1	-0.3	-0.1
Short access day 10 total infusions	0.2	0.3	0.6	0.6	0.8	-0.3	0.2	-0.3	0.5	0.3	0.4	-0.5	-0.7	0.6	-0.6	-0.7
Short access total infusions	0.1	0.1	0.2	0.0	0.4	-0.5	0.2	-0.4	0.5	0.2	0.2	-0.3	-0.4	0.3	-0.5	-0.3
Short access day 1 locomotion	0.2	0.4	1.1	-0.0	-0.1	-1.1	0.6	-1.0	-0.8	-0.7	-0.6	0.7	0.7	-0.3	0.5	0.1
Short access day 10 total locomotion	0.3	1.2	4.2	-1.9	-1.8	1.1	-2.0	1.2	-0.0	-0.0	-0.0	0.2	0.9	-0.8	0.5	1.0
Short access total locomotion	0.3	0.5	0.9	-1.0	-0.9	-0.2	-0.9	-0.2	-0.4	-0.5	-0.5	0.7	0.9	-0.8	0.6	0.9
One hour access (0.3 mA shock)	0.4	0.5	2.1	0.6	0.4	-1.1	1.5	-1.0	-0.6	-0.4	-0.4	0.3	0.3	0.1	0.2	-0.7
Compulsive drug intake	3.2	4.7	8.4	-0.7	-1.6	-1.9	1.0	-1.9	-2.9	-2.5	-2.5	2.8	2.7	-2.3	2.6	1.6
One hour access (shock baseline)	0.7	1.8	2.8	1.1	1.5	0.4	0.5	0.5	1.5	1.3	1.3	-1.6	-1.7	1.6	-1.6	-1.7
Social response proportion	0.5	0.6	1.7	-1.3	-1.3	0.2	-1.0	0.2	-0.4	-0.5	-0.5	0.1	0.2	-1.0	0.8	1.1
Social responses	0.3	0.4	1.4	-1.1	-1.0	0.8	-1.2	1.0	0.2	0.2	0.2	-0.3	-0.1	-0.2	0.1	0.1
Social time	1.9	3.1	5.0	-1.6	-2.1	-1.4	0.2	-1.2	-2.2	-1.9	-1.8	2.0	1.8	-1.8	2.1	1.7
Soleus weight	3.3	9.8	20.1	-3.8	-4.5	-1.7	-0.9	-1.5	-3.0	-3.1	-3.0	3.1	3.6	-3.7	3.2	3.6
Bone: stiffness	0.2	0.3	1.4	1.0	0.7	0.8	-1.2	0.4	0.2	0.1	-0.0	0.0	-0.1	-0.1	0.0	0.4
Tibialis anterior weight	0.2	0.7	1.9	1.4	1.3	0.9	-0.5	0.7	0.8	0.8	0.7	-0.2	-0.4	0.8	-0.8	-0.8
Time to tail flick, vehicle, before self-admin	0.3	0.3	1.0	1.0	0.4	-0.1	0.3	-0.3	-0.8	-0.5	-0.5	0.9	0.7	-0.2	0.6	-0.2
Time to tail flick, vehicle, after self-admin	0.1	0.2	0.5	-0.7	-0.6	-0.6	0.4	-0.4	-0.4	-0.4	-0.3	-0.1	0.4	-0.2	0.2	0.3
Time to tail flick, test, before self-admin	0.9	1.0	2.0	0.5	0.7	0.9	0.1	1.0	0.9	1.1	1.2	-1.1	-1.2	1.3	-1.0	-1.4
Time to tail flick, test, after self-admin	0.6	0.7	3.5	0.4	0.6	-0.8	1.9	-0.4	0.1	0.3	0.5	-0.9	-0.8	0.9	-0.4	-1.0
Delta time to tail flick, vehicle, before/after SA	0.3	0.4	1.1	-0.1	0.3	-0.8	1.1	-0.5	0.5	0.2	0.3	-0.9	-0.7	0.5	-0.6	-0.3
Delta time to tail flick, test, before/after SA	0.5	0.6	1.7	0.8	0.5	-1.1	1.2	-1.3	-0.8	-0.8	-0.8	0.5	0.4	-0.4	0.6	0.3
Tibia length	1.1	3.0	8.8	-2.5	-3.0	0.5	-2.1	0.6	-1.1	-1.0	-1.1	1.1	1.5	-1.9	1.5	2.5
Ambulatory time before self-admin	0.1	0.4	0.7	0.2	-0.1	-0.5	0.2	-0.7	-0.8	-0.7	-0.7	0.8	0.6	-0.6	0.7	0.4
Ambulatory time after self-admin	0.3	0.5	1.7	-0.8	-0.7	1.1	-1.3	1.2	0.4	0.5	0.5	-0.1	-0.2	0.0	-0.1	0.7
Bone: tissue strength	0.1	0.1	0.2	0.2	-0.0	-0.2	-0.2	-0.4	-0.2	-0.4	-0.4	0.2	0.1	-0.5	0.4	0.5
Total heroin consumption	0.0	0.0	0.1	-0.3	-0.4	0.0	-0.2	0.1	-0.2	-0.1	-0.1	-0.1	0.1	-0.1	0.2	-0.0
Bone: trabecular number	0.9	1.7	5.5	2.3	2.2	-1.3	2.4	-1.6	-0.4	-0.3	-0.3	0.7	-0.1	0.7	-0.3	-1.0
Bone: trabecular spacing	1.1	1.7	5.6	-2.1	-2.0	1.5	-2.4	1.7	0.6	0.4	0.4	-0.8	-0.2	-0.6	0.2	1.1
Bone: trabecular thickness	0.9	1.2	4.2	2.0	1.8	-1.1	1.8	-1.4	-0.6	-0.5	-0.5	0.9	0.4	0.3	0.0	-0.7
Bone: trabecular tissue density	0.6	1.0	2.0	-1.1	-0.5	0.7	-0.4	1.2	1.2	1.1	1.3	-1.4	-0.9	0.9	-1.1	-0.5
Water consumed over 24 hours	0.2	0.3	0.7	-0.8	-0.8	-0.3	-0.1	-0.2	-0.6	-0.6	-0.5	0.4	0.7	-0.7	0.6	0.6
Number of responses in last shaping day	0.9	1.1	6.9	-2.6	-2.1	-0.1	-0.3	0.4	-0.2	-0.3	-0.2	0.5	0.7	-0.9	0.5	1.2