Hub : Genes

Ppp1r3c

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Ppp1r3c 0.52 0.09 0.0e+00 0.34 0.42 0.43 0.44 8.0e-39 2.4e-50 7.2e-51 1.6e-52
2 Liver gene expression Ppp1r3c 0.02 0.02 4.9e-03 0.01 0.01 0 0 6.3e-02 4.9e-02 1.6e-01 7.3e-02
3 NAcc gene expression Ppp1r3c 0.49 0.1 0.0e+00 0.36 0.46 0.47 0.48 1.1e-43 2.7e-59 1.2e-61 4.2e-62
4 LHb gene expression Ppp1r3c 0.48 0.15 2.8e-10 0.18 0.23 0.26 0.35 4.0e-05 2.8e-06 6.2e-07 3.5e-09
5 Adipose gene expression Ppp1r3c 0.04 0.03 1.6e-03 0.01 0.03 0 0.01 1.7e-02 6.8e-04 9.2e-02 1.0e-02
6 pVTA gene expression Ppp1r3c 0.47 0.13 0.0e+00 0.32 0.41 0.43 0.43 1.6e-14 6.7e-19 2.1e-20 2.0e-20
7 IL gene expression Ppp1r3c 0.21 0.12 6.0e-04 0.06 0.14 0.07 0.07 1.9e-02 2.9e-04 9.6e-03 8.3e-03
8 Brain gene expression Ppp1r3c 0.45 0.11 0.0e+00 0.34 0.36 0.37 0.36 6.3e-33 4.9e-35 1.6e-35 1.1e-34
9 OFC gene expression Ppp1r3c 0.34 0.13 2.7e-06 0.16 0.24 0.23 0.25 1.4e-04 2.3e-06 3.1e-06 1.5e-06
10 BLA gene expression Ppp1r3c 0.46 0.14 0.0e+00 0.28 0.29 0.32 0.29 5.1e-15 1.1e-15 7.8e-18 1.2e-15
11 RMTg gene expression Ppp1r3c 0.32 0.14 2.4e-05 0.2 0.14 0.18 0.17 5.2e-06 1.4e-04 1.2e-05 2.0e-05
12 Eye gene expression Ppp1r3c 0.35 0.19 3.7e-03 0.03 0.02 0.01 0.02 1.2e-01 1.8e-01 2.4e-01 1.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density7.312.317.1-4.02.5-4.1-4.04.1-3.9-4.03.9-3.72.72.21.9
Area under the delay curve0.60.71.60.9-0.10.80.9-0.80.90.8-0.30.8-1.3-0.9-0.8
BMI with tail0.10.30.7-0.80.3-0.8-0.40.6-0.4-0.40.4-0.0-0.00.6-0.7
BMI without tail0.10.31.4-0.50.2-0.5-0.10.3-0.0-0.30.60.1-0.50.7-1.2
Body weight0.31.47.3-0.62.7-0.5-0.60.6-0.0-0.20.50.6-1.10.5-2.5
Weight adjusted by age0.80.92.0-1.0-0.4-1.0-0.50.9-1.0-0.91.4-1.21.1-0.21.2
Bone surface3.86.79.7-2.91.6-3.0-2.93.1-2.8-3.12.9-2.61.72.40.9
Bone volume3.96.710.1-2.92.4-3.0-3.03.2-2.8-2.92.7-2.62.01.80.9
Breakpoint value in progressive ratio session0.30.32.0-0.31.4-0.4-0.20.3-0.4-0.00.10.2-0.1-0.7-0.6
Number of licking bursts1.82.23.71.5-1.11.51.6-1.91.41.7-1.01.4-1.6-1.3-1.3
Context. condit. distance diff. score0.60.74.7-0.52.2-0.7-0.81.1-0.4-0.4-0.1-0.40.6-0.5-0.7
Locomotion velocity, session 10.70.86.00.2-2.50.40.5-0.70.20.10.5-0.1-0.61.00.8
Locomotion distance, session 10.10.10.4-0.1-0.6-0.00.1-0.1-0.0-0.00.2-0.1-0.30.00.6
Locomotion velocity, session 20.30.41.20.6-1.10.60.7-0.60.60.5-0.20.6-0.60.50.3
Locomotion distance, session 20.71.01.51.0-0.11.11.1-1.01.11.1-1.01.2-1.2-0.6-0.9
Locomotion velocity, session 30.10.10.50.20.70.10.10.10.30.2-0.20.4-0.10.1-0.6
Locomotion distance, session 30.60.72.30.71.50.60.3-0.20.80.7-1.10.9-0.4-0.7-1.1
Stereotopy head waving bouts, day 30.60.71.4-0.7-0.9-0.8-0.60.7-0.7-0.91.2-0.90.61.20.7
Stereotopy head waving duration, day 30.70.81.6-0.9-0.7-0.9-0.70.8-0.9-0.91.3-1.10.90.80.9
Locomotion velocity, session 70.40.42.40.11.60.00.10.10.20.4-0.60.40.3-1.3-0.4
Locomotion distance, session 70.30.42.4-0.11.6-0.1-0.10.3-0.10.2-0.50.10.4-1.1-0.0
Stereotopy head waving bouts, day 70.10.10.50.1-0.50.00.00.00.1-0.20.3-0.0-0.20.7-0.1
Stereotopy head waving duration, day 70.30.42.4-0.2-0.6-0.3-0.50.4-0.2-0.60.7-0.40.11.60.2
Locomotion velocity, session 80.10.10.3-0.50.5-0.4-0.40.3-0.4-0.30.1-0.20.10.0-0.1
Locomotion distance, session 80.30.52.20.21.50.20.20.10.30.5-0.90.4-0.4-1.2-0.9
Degree of sensitization distance0.10.11.1-0.1-0.0-0.00.3-0.2-0.10.3-0.1-0.10.0-1.10.3
Degree of sensitization stereotypy0.10.10.9-0.0-0.2-0.1-0.20.2-0.0-0.40.3-0.1-0.01.00.1
Conditioned locomotion0.40.51.4-0.71.0-0.6-0.70.7-0.7-0.40.4-0.61.2-0.30.4
Cocaine response after cond. corrected0.20.20.6-0.3-0.0-0.4-0.20.5-0.2-0.50.8-0.40.40.40.5
Cocaine response after cond. not corrected0.10.10.40.20.60.10.20.10.30.00.00.2-0.2-0.3-0.2
Cocaine response before conditioning1.41.72.71.20.51.31.1-1.21.31.3-1.71.6-1.5-1.0-1.5
Saline control response0.30.42.10.60.50.40.5-0.30.60.7-0.70.40.3-1.40.2
Bone: connectivity density5.99.312.9-3.61.2-3.5-3.33.4-3.6-3.53.5-3.32.22.32.0
Bone: cortical apparent density0.50.62.90.6-1.70.61.0-0.80.60.6-0.40.40.2-0.40.8
Bone: cortical area0.71.17.0-0.42.6-0.5-1.01.0-0.2-0.60.2-0.00.20.4-1.7
Bone: cortical porosity0.10.10.30.3-0.30.40.4-0.50.30.5-0.50.40.1-0.2-0.1
Bone: cortical porosity0.00.00.10.10.10.10.1-0.20.10.2-0.30.20.10.1-0.2
Bone: cortical thickness0.71.15.11.01.30.80.6-0.51.10.8-0.61.1-1.0-0.4-2.3
Bone: cortical thickness0.80.91.61.10.10.91.1-0.81.11.0-0.71.0-0.5-1.1-1.3
Bone: cortical tissue density0.50.63.10.6-1.80.61.0-0.70.50.5-0.30.30.2-0.40.9
Condit. Reinf. active minus inactive responses1.31.52.41.5-0.31.41.3-1.31.51.4-1.31.5-0.8-0.8-0.8
Condit. Reinf. active-inactive response ratio0.50.51.70.8-1.30.90.7-0.90.80.6-0.60.6-0.20.30.4
Condit. Reinf. active responses0.70.91.41.10.90.90.7-0.61.21.0-1.11.2-0.3-1.2-0.8
Condit. Reinf. inactive responses0.40.43.20.01.8-0.2-0.20.50.10.0-0.00.20.1-1.0-0.8
Incentive salience index mean2.93.45.02.20.02.11.9-1.82.22.0-2.02.1-1.6-1.6-1.6
Condit. Reinf. lever presses3.03.95.22.2-0.22.12.1-1.92.32.1-2.12.1-2.0-2.0-1.9
Condit. Reinf. active minus inactive responses0.70.92.20.71.50.50.7-0.20.70.8-1.11.1-0.7-1.2-1.4
Condit. Reinf. active-inactive response ratio0.40.40.80.50.60.40.7-0.20.50.6-0.70.8-0.5-0.8-0.9
Condit. Reinf. active responses0.40.54.4-0.12.1-0.3-0.30.70.0-0.2-0.20.3-0.0-0.3-1.1
Condit. Reinf. inactive responses0.40.52.1-0.51.5-0.6-0.90.9-0.4-0.70.5-0.40.40.6-0.3
Condit. Reinf. lever presses0.10.10.2-0.20.5-0.3-0.30.4-0.1-0.30.1-0.10.20.2-0.2
Condit. Reinf. lever reinforcers received0.30.43.00.01.7-0.2-0.10.50.1-0.0-0.20.4-0.1-0.4-1.0
Conditioned reinforcement - actives1.31.32.1-1.51.3-1.3-1.31.1-1.4-1.21.4-0.70.60.80.3
Conditioned reinforcement - inactives2.32.64.9-1.91.1-1.9-1.81.7-2.2-1.71.6-1.31.21.20.9
Conditioned locomotion1.82.23.6-1.90.2-1.7-1.61.5-1.6-1.71.6-1.21.11.81.2
Patch foraging indifference point 0 sec0.30.51.90.1-0.30.20.6-0.60.40.30.20.9-1.40.9-1.3
Patch foraging indifference point AUC2.02.34.71.6-0.61.61.6-1.61.61.5-1.31.6-1.7-0.7-2.2
Delay disc. indifference point, 0s delay0.80.93.30.71.20.60.8-0.50.61.0-0.70.7-0.9-1.8-1.1
Delay disc. indifference point, 16s delay0.10.10.3-0.20.2-0.2-0.30.3-0.3-0.30.6-0.3-0.10.20.1
Delay disc. indifference point, 2s delay0.10.10.3-0.2-0.3-0.30.10.2-0.1-0.20.5-0.40.3-0.20.6
Delay disc. indifference point, 24s delay2.92.85.61.9-0.21.91.5-1.71.81.7-1.51.7-2.4-1.3-1.8
Delay disc. indifference point, 4s delay0.90.91.60.90.60.81.0-0.81.11.0-0.60.9-1.2-1.3-1.2
Delay disc. indifference point, 8s delay1.31.32.21.3-1.21.31.5-1.41.31.2-0.60.9-1.4-0.7-0.6
Indifference point function ln k1.31.82.4-1.51.4-1.5-1.41.6-1.3-1.31.1-1.21.40.71.4
Indifference point function log k1.31.82.4-1.51.4-1.5-1.41.6-1.3-1.31.1-1.21.40.71.4
Patch foraging total patch changes 0 sec0.30.51.90.1-0.20.20.4-0.50.30.20.20.8-1.41.0-1.2
Patch foraging total patch changes 12 sec1.01.32.31.0-1.51.11.4-1.41.01.0-0.81.2-1.4-0.1-1.3
Patch foraging total patch changes 18 sec0.60.72.90.5-0.50.60.9-0.90.70.7-0.20.9-1.2-0.1-1.7
Patch foraging total patch changes 24 sec1.41.76.61.10.01.11.3-1.31.11.2-0.71.4-1.7-0.2-2.6
Patch foraging total patch changes 6 sec1.21.84.11.2-1.31.31.3-1.61.31.0-0.71.3-1.90.5-2.0
Patch foraging time to switch 0 sec0.20.31.50.4-1.20.40.5-0.70.40.5-0.3-0.10.1-0.70.7
Patch foraging water rate 0 sec0.10.20.8-0.20.9-0.2-0.00.3-0.1-0.10.20.30.20.3-0.7
Patch foraging water rate 12 sec0.10.20.7-0.50.8-0.4-0.40.3-0.1-0.40.30.2-0.30.9-0.3
Patch foraging water rate 18 sec0.20.31.7-0.61.3-0.5-0.50.5-0.6-0.40.10.0-0.00.40.1
Patch foraging water rate 24 sec0.30.43.9-0.12.0-0.2-0.50.40.00.0-0.10.2-0.1-0.2-0.9
Patch foraging water rate 6 sec0.20.30.7-0.50.1-0.5-0.60.6-0.5-0.60.8-0.60.70.9-0.1
Seeking ratio, delayed vs. immediate footshock0.10.10.30.40.40.30.1-0.30.30.4-0.60.2-0.1-0.4-0.5
Distance traveled before self-admin0.80.91.51.00.21.00.9-0.71.20.9-1.10.8-0.8-1.0-0.9
Distance traveled after self-admin2.42.75.3-1.6-0.2-1.7-1.71.7-1.8-1.71.7-2.31.70.41.9
Extensor digitorum longus weight0.41.74.90.92.20.70.6-0.50.91.2-1.71.1-0.6-1.7-2.0
Bone: elastic displacement0.80.95.8-0.3-2.4-0.30.4-0.2-0.4-0.20.5-0.50.40.61.8
Bone: elastic work0.91.13.8-0.9-1.9-0.80.00.5-1.0-0.70.9-1.00.60.81.9
Bone: endosteal estimation3.16.810.7-2.82.6-2.9-3.23.3-2.7-2.92.4-2.62.01.91.1
Bone: endosteal perimeter3.77.712.5-3.12.5-3.1-3.53.4-3.0-3.12.6-2.82.12.01.1
Epididymis fat weight0.30.62.00.41.10.40.2-0.50.60.7-0.40.9-1.4-0.6-1.3
Delta time in closed arm before/after self-admin2.82.74.21.7-0.21.71.4-1.81.91.8-1.62.0-2.0-0.7-2.0
Delta time in open arm before/after self-admin0.80.81.9-0.40.3-0.6-0.51.1-0.8-0.70.5-1.31.4-0.71.3
Diff in mean of infusions in LGA sessions0.30.30.80.40.90.30.2-0.20.60.5-0.60.6-0.4-0.6-0.9
Delay discount exponential model param0.80.81.9-1.00.1-0.9-1.00.9-1.1-0.90.4-0.81.40.80.9
Extinction: sum of active levers before priming0.20.20.60.40.80.50.2-0.20.60.4-0.50.6-0.3-0.2-0.7
Active lever presses in extinction session 60.80.72.1-0.91.4-0.9-0.81.0-1.0-0.50.6-0.70.8-0.90.2
Bone: final force0.30.41.7-0.41.3-0.4-0.50.6-0.2-0.40.40.1-0.30.8-1.3
Bone: final moment0.30.61.5-0.61.0-0.7-0.70.8-0.5-0.80.7-0.3-0.11.2-0.8
Food consumed during 24 hour testing period0.40.41.30.6-0.10.60.3-0.70.60.5-0.60.7-1.10.2-1.1
Glucose0.10.10.50.30.30.40.0-0.30.30.2-0.30.30.10.2-0.7
Heart weight0.20.32.3-0.0-0.80.1-0.2-0.2-0.1-0.20.30.0-0.61.5-0.7
Delay discount hyperbolic model param0.60.61.4-0.80.2-0.8-0.90.8-0.9-0.80.3-0.71.20.70.7
Intermittent access intake day 1-15 change2.82.75.2-2.30.6-2.1-1.61.6-1.7-1.81.9-1.01.02.30.6
Intermittent access intake escalation2.52.46.2-2.20.5-2.0-1.41.4-1.6-1.71.8-0.70.62.50.4
Intermittent access intake escalation 21.31.32.9-1.70.2-1.5-0.91.0-1.2-1.21.3-0.60.61.70.4
Intermitt. access day 1 inactive lever presses0.80.81.5-0.8-0.3-0.9-0.71.1-1.0-1.00.8-1.21.10.61.1
Intermitt. access day 15 inactive lever presses4.34.86.6-2.10.2-2.1-2.42.4-2.3-2.62.4-2.51.82.12.3
Intermitt. access escalation Index0.90.81.70.90.10.90.7-0.70.90.9-1.30.9-0.9-1.0-0.7
Intermittent access day 1 total infusions0.30.41.7-0.71.3-0.7-0.70.6-0.8-0.40.4-0.2-0.0-0.1-0.2
Intermittent access day 15 total infusions2.12.44.6-2.11.6-1.9-1.81.5-1.8-1.61.5-0.40.02.1-0.2
Intermittent access terminal intake (last 3 days)1.61.83.9-2.01.0-1.8-1.41.2-1.7-1.31.4-0.50.11.70.1
Intermittent access total infusions0.80.91.9-1.41.4-1.3-1.20.9-1.3-0.80.9-0.3-0.00.8-0.2
Intermittent access day 1 locomotion0.20.21.3-0.21.1-0.2-0.20.3-0.3-0.0-0.00.3-0.50.1-0.8
Intermittent access day 15 total locomotion1.71.83.3-1.70.5-1.5-1.51.4-1.5-1.51.5-1.00.81.80.7
Intermittent access total locomotion0.20.20.5-0.70.6-0.6-0.40.4-0.7-0.30.4-0.1-0.20.2-0.2
Intermittent access standard deviation1.21.32.7-1.40.5-1.4-1.31.1-1.2-1.31.1-0.70.71.60.7
Left kidney weight0.72.17.60.81.51.00.7-1.01.31.1-0.91.8-2.20.1-2.8
Right kidney weight1.33.79.11.60.81.81.4-1.91.91.7-1.62.4-2.8-0.2-3.0
Cocaine induced anxiety0.30.32.00.50.20.50.4-0.30.20.5-0.60.1-0.3-1.4-0.2
Post-drug Anxiety0.30.31.1-0.1-0.6-0.1-0.30.4-0.4-0.40.2-1.00.5-0.41.1
Baseline Anxiety0.40.50.9-0.4-0.6-0.4-0.50.5-0.5-0.70.7-0.80.80.90.9
Tail length0.41.14.70.62.00.50.4-0.21.00.6-0.21.0-1.2-0.3-2.2
Length with tail0.51.79.70.33.10.3-0.1-0.00.60.4-0.11.1-1.6-0.1-2.5
Length without tail0.51.08.00.32.80.3-0.20.00.40.5-0.70.8-0.8-0.9-1.1
Times rat made contact with spout0.30.32.30.20.70.10.4-0.10.20.5-0.40.2-0.2-1.5-0.5
Lifetime Intake0.80.91.9-1.41.1-1.2-1.00.8-1.3-0.80.9-0.2-0.10.8-0.2
Liver weight, left0.60.97.7-0.22.8-0.3-0.80.6-0.0-0.1-0.00.20.0-0.5-1.4
Liver weight, right0.81.43.20.51.80.60.7-0.80.81.1-1.11.5-1.4-1.1-1.8
Locomotor activity0.10.10.70.2-0.80.20.5-0.50.10.30.20.1-0.30.10.0
Locomotor testing distance0.20.31.50.4-1.20.40.6-0.70.30.40.10.4-0.50.20.5
Locomotor testing rearing0.00.10.30.00.5-0.00.1-0.00.00.2-0.00.20.4-0.6-0.3
Locomotion in novel chamber2.22.74.3-1.81.0-1.9-1.71.9-1.9-1.61.4-1.82.10.41.3
Locomotion in novel chamber post-restriction0.60.85.7-0.52.4-0.7-0.90.9-0.5-0.40.3-0.30.3-0.3-0.5
Fecal boli incidents, locomotor time 10.10.10.70.10.30.20.2-0.20.20.4-0.60.2-0.4-0.9-0.3
Change in fecal boli incidents, locomotor task0.10.10.20.3-0.20.30.4-0.30.20.2-0.20.4-0.00.3-0.2
Time >=10cm from walls, locomotor time 10.80.87.10.32.70.1-0.60.60.1-0.1-0.6-0.00.1-0.5-0.9
Bouts of movement, locomotor time 10.20.20.6-0.70.7-0.6-0.10.2-0.4-0.20.60.30.1-0.2-0.4
Total resting periods, locomotor time 10.20.20.7-0.80.8-0.7-0.10.3-0.4-0.20.50.30.2-0.3-0.4
Rest time, locomotor task time 10.60.71.4-1.2-0.3-1.1-0.50.6-1.1-0.81.1-0.61.1-0.00.9
Distance moved, locomotor task time 11.92.13.41.90.51.71.4-1.21.61.4-1.71.4-1.7-0.8-1.5
Vertical activity count, locomotor time 10.20.20.40.60.20.60.3-0.40.60.4-0.60.4-0.60.3-0.6
Time >=10cm from walls, locomotor time 21.11.22.21.01.20.90.8-0.60.80.9-1.20.8-1.5-1.3-1.4
Bouts of movement, locomotor time 21.61.73.30.8-1.11.01.7-1.61.11.5-1.01.5-1.8-1.3-1.0
Total resting periods, locomotor time 21.92.03.60.9-1.01.11.8-1.81.21.7-1.01.7-1.9-1.4-1.2
Rest time, locomotor task time 20.30.30.90.10.30.30.6-0.70.40.7-0.20.7-0.3-0.9-0.7
Distance moved, locomotor task time 20.50.61.21.10.70.90.6-0.20.90.6-1.10.6-0.7-0.4-0.9
Vertical activity count, locomotor time 20.20.20.40.4-0.60.50.4-0.30.30.2-0.50.3-0.50.4-0.1
Light reinforcement 10.91.63.2-1.70.1-1.6-1.01.3-1.7-1.31.8-1.40.70.70.3
Light reinforcement 20.50.75.6-0.4-2.4-0.30.6-0.3-0.6-0.20.8-0.50.20.20.8
Bone: marrow area3.47.411.7-3.02.6-3.0-3.43.4-2.8-3.12.6-2.72.12.01.2
Bone: maximum diameter5.19.315.2-3.23.6-3.3-3.93.9-3.0-3.32.7-2.92.91.90.6
Bone: maximum force1.11.83.0-1.41.7-1.4-1.61.7-1.2-1.51.3-1.00.51.5-0.6
Bone: maximum moment1.32.33.8-1.61.3-1.6-1.81.8-1.5-1.81.6-1.30.72.0-0.2
Mean time between licks in bursts0.40.62.80.5-1.70.60.6-0.80.40.4-0.40.5-0.71.0-0.1
Mean num. licks in bursts1.21.42.7-1.21.4-1.3-1.21.7-1.1-1.20.6-1.21.40.31.0
Cd content in liver0.30.30.90.5-0.70.50.3-0.50.50.2-0.30.4-1.00.8-0.6
Co content in liver1.11.33.6-0.9-1.9-0.8-0.50.6-1.0-1.01.1-1.00.61.51.9
Cu content in liver0.70.86.3-0.1-2.5-0.00.4-0.4-0.3-0.30.8-0.5-0.50.61.2
Fe content in liver3.03.66.12.0-2.02.02.5-2.21.91.8-1.71.8-2.1-0.9-1.2
K content in liver0.50.53.20.3-0.20.40.9-0.60.30.8-0.50.4-0.0-1.80.2
Mg content in liver0.70.81.60.8-0.90.91.3-1.00.81.0-0.60.8-0.5-1.1-0.2
Mn content in liver1.21.42.41.2-1.21.31.4-1.51.21.3-1.21.1-1.2-0.7-0.6
Na content in liver2.62.75.01.7-0.51.72.1-1.71.71.9-1.51.9-1.3-2.2-0.8
Rb content in liver0.10.10.50.20.60.20.2-0.10.20.3-0.10.2-0.2-0.7-0.7
Se content in liver11.113.529.63.8-5.44.04.6-4.63.63.5-2.73.3-3.9-1.2-1.1
Sr content in liver2.92.63.8-1.6-0.6-1.6-1.51.5-1.6-1.81.8-1.71.61.92.0
Zn content in liver6.77.412.02.9-2.82.93.5-3.32.72.9-2.82.7-2.3-2.0-1.0
Bone: minimum diameter2.24.212.5-1.93.5-2.0-2.92.6-1.7-2.11.3-1.41.11.7-0.7
Time in familiar zone, hab. session 10.40.40.6-0.7-0.3-0.6-0.60.5-0.6-0.70.6-0.60.60.80.8
Time in novel zone, hab. session 10.50.50.90.8-0.50.80.9-1.00.70.9-0.70.7-0.5-0.7-0.5
Total zone transitions, hab. session 10.20.30.6-0.50.1-0.5-0.60.5-0.5-0.50.8-0.60.80.10.8
Total locomotion distance, hab. session 10.30.51.50.6-0.50.60.8-0.60.60.7-0.50.40.5-1.20.7
Locomotion velocity, hab. session 10.60.92.80.9-0.40.91.2-0.91.01.1-0.90.7-0.0-1.70.3
Time in familiar zone, hab. session 20.10.10.8-0.1-0.90.0-0.0-0.2-0.1-0.10.3-0.10.10.60.6
Time in novel zone, hab. session 20.00.00.1-0.20.1-0.3-0.20.2-0.2-0.20.1-0.20.30.00.0
Total zone transitions, hab. session 20.20.30.60.5-0.80.60.5-0.50.60.3-0.10.6-0.70.5-0.1
Total locomotion distance, hab. session 20.40.50.90.8-0.70.80.9-0.80.80.7-0.60.8-0.5-0.30.1
Locomotion velocity, hab. session 20.60.71.30.9-0.51.01.2-1.01.01.0-0.81.0-0.7-0.8-0.2
Novel to familiar place preference ratio0.80.81.4-1.20.8-1.2-0.90.9-1.2-0.80.9-1.10.1-0.7-0.1
Novelty place preference1.01.01.8-1.30.7-1.3-1.01.1-1.3-0.91.1-1.40.3-0.60.1
Time in novel zone, NPP test0.70.71.4-1.10.5-1.1-0.80.8-1.1-0.70.9-1.20.3-0.6-0.0
Total zone transitions, NPP test0.91.32.01.3-0.41.41.2-1.31.41.3-0.91.3-1.2-0.8-0.8
Total locomotion distance, NPP test1.31.72.71.5-0.81.41.6-1.41.51.5-1.11.2-1.1-1.6-0.8
Locomotion velocity, NPP test1.52.13.71.6-0.51.51.7-1.41.61.6-1.21.3-1.5-1.9-1.1
Intraocular pressure0.50.71.3-1.00.4-1.0-0.60.8-1.0-0.91.1-0.7-0.10.8-0.6
Delta distance traveled before/after self-admin3.53.75.1-2.20.5-2.3-2.22.0-2.3-2.02.2-2.21.81.11.7
Delta ambulatory time before/after self-admin4.14.56.2-2.41.0-2.5-2.52.4-2.5-2.22.3-2.41.91.11.6
Parametrial fat weight0.51.04.60.41.30.40.6-0.50.70.8-0.71.2-1.2-0.3-2.1
Pavlov. Cond. lever latency2.22.85.0-1.7-0.6-1.6-1.51.5-1.7-1.91.9-1.81.62.21.8
Pavlov. Cond. magazine entry latency2.83.65.52.2-0.42.22.0-2.02.22.0-2.22.4-1.7-1.0-1.4
Pavlov. Cond. change in total contacts2.93.14.62.1-0.62.01.8-1.82.11.8-2.02.2-1.8-0.6-1.4
Pavlov. Cond. index score3.74.76.52.30.62.32.0-2.02.42.3-2.52.5-2.1-2.0-2.2
Pavlov. Cond. latency score4.05.16.92.40.82.32.1-2.02.42.4-2.62.6-2.2-2.4-2.4
Pavlov. Cond. lever contacts3.23.84.92.10.52.01.9-1.82.12.1-2.22.2-1.9-2.2-1.9
Pavlov. Cond. magazine entry number1.41.82.8-1.50.2-1.6-1.11.4-1.5-1.41.6-1.71.40.31.2
Pavlov. Cond. intertrial magazine entries0.20.21.3-0.21.1-0.3-0.40.5-0.1-0.20.3-0.30.4-0.5-0.3
Pavlov. Cond. lever-magazine prob. diff.4.25.27.22.50.32.42.2-2.22.52.5-2.72.7-2.2-2.1-2.1
Pavlov. Cond. response bias2.42.94.21.9-0.62.01.6-1.91.91.8-1.92.0-1.7-0.8-1.3
Pavlov. Cond. lever latency0.10.20.90.10.60.20.2-0.20.00.4-0.50.2-0.1-1.0-0.4
Pavlov. Cond. magazine entry latency1.11.22.11.3-0.41.31.2-1.21.41.2-1.21.3-0.7-0.6-0.9
Pavlov. Cond. change in total contacts0.40.61.00.90.30.80.8-0.61.00.8-0.90.8-0.6-0.7-0.5
Pavlov. Cond. index score0.20.30.80.70.20.60.5-0.50.90.5-0.50.7-0.4-0.2-0.6
Pavlov. Cond. latency score0.10.20.50.50.30.40.3-0.20.70.3-0.30.5-0.2-0.1-0.5
Pavlov. Cond. lever contacts0.00.00.30.1-0.20.1-0.00.00.2-0.10.10.00.10.50.1
Pavlov. Cond. magazine entry number2.12.64.3-1.90.7-1.9-1.81.8-2.1-1.81.7-1.81.20.91.2
Pavlov. Cond. intertrial magazine entries0.30.42.5-0.21.6-0.3-0.30.3-0.20.0-0.10.0-0.3-0.8-0.9
Pavlov. Cond. lever-magazine prob. diff.0.40.61.20.90.20.90.8-0.71.10.8-0.70.9-0.5-0.4-0.8
Pavlov. Cond. response bias0.60.81.51.1-0.51.11.0-1.01.20.9-0.81.0-0.8-0.4-0.6
Time in closed arm before self-admin0.30.30.7-0.6-0.4-0.6-0.10.2-0.8-0.20.5-0.50.7-0.60.8
Time in closed arm after self-admin2.62.64.01.7-0.21.61.6-1.81.81.9-1.61.7-1.4-2.0-1.4
Time in open arm before self-admin0.20.20.90.0-0.40.20.1-0.30.50.10.10.4-1.00.9-0.7
Time in open arm after self-admin2.02.23.1-1.50.5-1.6-1.51.8-1.5-1.71.7-1.71.50.91.4
Bone: periosteal estimation2.75.69.8-2.43.1-2.5-3.03.0-2.2-2.62.1-2.11.71.70.0
Bone: periosteal perimeter2.03.49.0-1.83.0-2.0-2.42.4-1.7-1.91.3-1.51.20.9-0.4
Bone: post-yield work0.81.24.1-0.52.0-0.5-1.40.9-0.3-0.80.5-0.2-0.71.0-2.0
Progressive ratio test 1 active lever presses1.31.32.3-1.31.0-1.3-1.31.3-1.5-1.21.2-0.91.00.90.5
Progressive ratio test 1 breakpoint1.31.42.6-1.50.9-1.4-1.21.3-1.6-1.21.3-0.90.91.10.5
Progressive ratio test 1 inactive lever presses1.92.14.5-2.11.1-2.0-1.41.5-2.1-1.41.6-0.90.41.00.4
Progressive ratio test 2 active lever presses2.83.05.3-2.31.6-2.2-1.91.9-1.9-1.82.0-1.10.91.70.4
Progressive ratio test 2 breakpoint3.74.16.9-2.61.9-2.6-2.32.2-2.2-2.12.2-1.51.21.80.6
Progressive ratio test 2 inactive lever presses3.43.96.1-2.50.8-2.4-2.12.1-2.4-2.12.3-1.91.51.41.4
Incentive Sensitization - Responses2.93.06.7-2.61.5-2.5-1.81.8-1.8-1.81.9-0.90.31.70.2
Incentive Sensitization - Breakpoint3.13.16.8-2.61.5-2.5-1.91.9-1.9-1.91.9-1.00.41.70.3
Sum of active levers in priming session hrs 5-60.80.82.5-0.7-1.1-0.8-0.30.5-1.1-0.80.7-0.91.10.41.6
Progressive ratio0.60.71.70.51.20.40.3-0.40.60.7-0.80.8-1.2-0.7-1.3
Food seeking constrained by brief footshock0.40.53.1-0.31.8-0.2-0.90.40.2-0.30.10.1-0.50.6-0.9
Seeking ratio, punishment vs. effort0.10.10.50.0-0.10.1-0.30.10.1-0.30.4-0.20.30.70.2
Retroperitoneal fat weight0.10.21.2-0.01.0-0.0-0.30.20.2-0.00.30.1-0.50.1-1.1
Reaction time number correct1.31.93.4-1.41.2-1.4-1.61.4-1.5-1.21.3-1.61.8-0.11.1
Reaction time mean minus median0.60.72.6-0.8-0.5-0.7-1.00.7-0.8-1.01.0-0.60.31.60.7
Reaction time mean minus median AUC0.50.72.3-0.6-0.9-0.6-0.70.6-0.7-0.91.0-0.6-0.11.51.0
Reaction time num false alarms0.40.52.40.41.60.30.4-0.10.40.5-0.50.6-0.0-1.1-1.2
Reaction time num false alarms AUC0.50.71.60.71.20.70.6-0.50.70.7-0.70.9-0.4-1.0-1.3
Reaction time trials correct on left1.31.93.4-1.41.2-1.4-1.61.4-1.5-1.21.3-1.61.8-0.11.1
Reaction time trials on left1.21.83.3-1.31.2-1.4-1.51.4-1.4-1.21.2-1.61.8-0.11.0
Reaction time mean0.71.04.11.1-2.01.10.9-1.21.10.7-0.60.7-0.80.70.3
Reaction time mean AUC0.91.35.21.1-2.31.21.0-1.31.10.8-0.70.8-0.90.70.4
Median of all reaction times1.01.45.51.3-2.31.41.2-1.41.30.9-0.90.7-0.70.50.4
Reaction time omissions0.10.10.30.6-0.10.50.3-0.20.60.2-0.10.3-0.00.4-0.3
Reaction time false alarm rate0.81.12.31.00.70.91.0-0.81.01.0-1.01.3-1.0-0.7-1.5
Reaction time premature initiation rate0.20.31.6-0.61.3-0.6-0.70.5-0.3-0.40.20.10.50.30.0
Reaction time premature initiations1.21.74.3-1.42.1-1.4-1.71.4-1.2-1.11.0-0.91.50.30.5
Std. dev. reaction times0.30.42.90.1-1.20.2-0.1-0.10.2-0.30.40.1-0.51.70.6
Reaction time trials completed1.21.83.3-1.31.2-1.4-1.51.4-1.4-1.21.2-1.61.8-0.11.0
Reaction time trials AUC0.81.22.5-1.11.1-1.1-1.21.1-1.1-0.90.9-1.31.6-0.40.9
Run reversals in cocaine runway, females0.60.60.9-0.7-0.8-0.7-0.40.6-0.7-0.80.8-1.01.00.51.0
Run reversals in cocaine runway, males0.60.61.40.7-0.10.80.6-0.80.90.7-0.60.9-1.2-0.1-0.9
Latency to leave start box in cocaine runway0.40.51.3-0.51.1-0.8-0.41.1-0.4-0.60.6-0.71.00.1-0.0
Latency to leave start box in cocaine runway, F0.10.10.4-0.20.6-0.40.10.50.0-0.10.1-0.10.4-0.1-0.4
Latency to leave start box in cocaine runway, M0.40.41.1-0.31.0-0.5-0.60.9-0.4-0.60.7-0.70.80.20.2
Std. dev. time between licks in bursts1.11.34.11.1-2.01.21.1-1.51.01.0-0.80.9-1.30.4-0.1
Total sessions with >9 infusions0.30.40.8-0.90.3-0.7-0.30.1-0.8-0.20.70.4-0.80.9-0.7
Short access day 1 total inactive lever presses4.55.08.2-2.8-0.3-2.7-2.12.2-2.9-2.42.6-2.31.81.72.0
Short access day 10 total inactive lever presses0.10.20.9-0.1-1.0-0.10.5-0.1-0.10.10.1-0.10.2-0.50.5
Short access day 1 total infusions0.10.10.3-0.3-0.1-0.20.2-0.3-0.40.10.20.5-0.50.3-0.5
Short access day 10 total infusions0.20.31.3-0.4-0.3-0.20.1-0.4-0.50.1-0.00.7-1.10.7-0.5
Short access total infusions0.40.51.3-1.10.7-1.0-0.60.4-1.2-0.50.70.1-0.40.7-0.3
Short access day 1 locomotion0.70.72.20.2-0.10.40.9-0.90.40.8-0.31.3-1.3-0.1-1.5
Short access day 10 total locomotion0.10.10.20.1-0.10.20.5-0.2-0.10.3-0.40.4-0.2-0.4-0.4
Short access total locomotion0.30.30.8-0.0-0.40.10.7-0.5-0.10.4-0.20.8-0.90.0-0.8
One hour access (0.3 mA shock)4.85.69.8-3.12.5-2.9-2.82.4-2.7-2.42.5-1.61.42.00.7
Compulsive drug intake0.30.32.1-0.01.5-0.1-0.60.50.1-0.2-0.0-0.30.0-0.0-0.4
One hour access (shock baseline)1.61.84.3-2.10.8-1.8-1.51.1-1.8-1.41.4-0.70.61.30.5
Social response proportion1.92.03.3-1.5-0.5-1.5-1.31.3-1.7-1.41.4-1.81.70.71.5
Social responses2.02.64.0-2.0-0.1-1.8-1.71.5-2.0-1.81.8-1.71.21.71.2
Social time0.60.82.10.7-1.00.80.9-1.10.70.8-0.60.9-1.5-0.1-1.2
Soleus weight1.23.45.2-1.90.7-1.9-2.32.0-1.9-2.01.9-2.01.91.81.3
Bone: stiffness0.71.16.8-0.32.6-0.3-0.90.7-0.2-0.3-0.10.1-0.40.1-2.1
Tibialis anterior weight0.51.66.20.62.50.40.4-0.20.61.1-1.50.8-0.1-2.5-1.5
Time to tail flick, vehicle, before self-admin0.30.31.5-0.4-1.2-0.40.2-0.0-0.5-0.20.5-0.4-0.20.20.8
Time to tail flick, vehicle, after self-admin0.80.92.90.31.60.30.6-0.40.60.9-0.61.0-0.3-1.7-1.2
Time to tail flick, test, before self-admin0.80.83.8-0.71.9-0.9-0.91.0-0.7-0.50.3-0.60.9-0.7-0.3
Time to tail flick, test, after self-admin0.10.10.30.2-0.30.20.6-0.40.20.4-0.10.3-0.5-0.4-0.2
Delta time to tail flick, vehicle, before/after SA1.31.38.30.32.90.2-0.10.10.60.6-0.70.70.2-1.8-1.6
Delta time to tail flick, test, before/after SA0.30.30.70.4-0.40.50.6-0.60.50.5-0.20.6-0.9-0.0-0.5
Tibia length0.00.10.50.10.50.0-0.10.20.2-0.20.40.10.00.5-0.7
Ambulatory time before self-admin1.31.42.11.3-0.41.31.3-1.11.41.2-1.31.2-1.2-1.1-0.9
Ambulatory time after self-admin2.02.24.0-1.60.2-1.8-1.51.7-1.7-1.41.5-2.01.50.21.4
Bone: tissue strength0.50.42.3-0.5-1.1-0.3-0.50.1-0.5-0.50.4-0.5-0.11.50.6
Total heroin consumption0.30.41.1-0.91.1-0.8-0.60.8-0.7-0.60.5-0.20.3-0.0-0.1
Bone: trabecular number6.09.412.8-3.61.7-3.5-3.53.5-3.5-3.53.5-3.22.12.41.7
Bone: trabecular spacing3.54.66.62.6-0.82.52.3-2.42.62.4-2.52.3-1.6-1.4-1.4
Bone: trabecular thickness3.64.25.8-2.41.6-2.4-2.42.4-2.3-2.42.1-2.11.51.71.1
Bone: trabecular tissue density1.11.52.8-1.41.5-1.5-1.31.7-1.3-1.20.9-1.01.40.30.6
Water consumed over 24 hours1.21.44.11.00.51.01.2-1.11.01.4-1.50.9-0.6-2.0-1.4
Number of responses in last shaping day1.61.72.9-1.70.7-1.6-1.31.4-1.7-1.41.6-0.90.71.30.5