Hub : Genes

Ppard

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Ppard 0.17 0.1 2.1e-04 0.2 0.18 0.14 0.18 1.8e-05 4.5e-05 3.5e-04 3.7e-05
2 Brain gene expression Ppard 0.07 0.04 2.4e-06 0.06 0.06 0.05 0.06 2.4e-06 1.5e-06 8.6e-06 3.7e-06
3 Adipose mRNA stability Ppard 0.04 0.03 8.9e-04 0.02 0.02 0.01 0.02 2.7e-03 2.5e-03 7.1e-03 6.1e-03
4 Adipose alternative TSS XM_006256167.4 0.02 0.02 5.4e-03 0.02 0.01 0 0.01 4.8e-03 1.9e-02 8.2e-02 1.8e-02
5 Adipose alternative TSS XM_006256167.4 0.03 0.02 2.5e-03 0.02 0.01 0.01 0.01 3.6e-03 3.5e-02 1.7e-02 1.1e-02
6 Adipose gene expression Ppard 0.14 0.06 0.0e+00 0.21 0.21 0.2 0.2 5.5e-23 1.4e-22 7.4e-22 2.8e-22
7 BLA gene expression Ppard 0.3 0.12 3.6e-11 0.22 0.17 0.17 0.21 3.9e-12 3.0e-09 1.7e-09 1.5e-11
8 PL gene expression Ppard 0.17 0.07 0.0e+00 0.15 0.15 0.15 0.16 1.6e-16 2.9e-16 1.2e-16 6.7e-17
9 NAcc gene expression Ppard 0.05 0.03 6.6e-05 0.02 0.03 0.02 0.03 7.4e-04 1.7e-04 7.5e-04 1.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.20.30.8-0.0-0.00.90.60.5-0.5-0.50.30.9
Area under the delay curve0.20.20.80.2-0.1-0.3-0.1-0.60.60.4-0.6-0.9
BMI with tail1.23.88.62.9-2.5-1.7-1.2-1.21.21.8-1.6-2.4
BMI without tail0.30.62.30.7-0.5-1.2-0.8-0.50.50.4-0.3-1.5
Body weight3.313.726.92.5-2.3-4.2-3.4-4.04.03.3-3.8-5.2
Weight adjusted by age0.91.01.90.4-0.4-0.6-0.5-1.41.41.0-1.3-1.1
Bone surface0.00.10.5-0.70.5-0.10.1-0.10.1-0.0-0.10.1
Bone volume0.00.00.0-0.20.1-0.00.1-0.10.1-0.1-0.1-0.1
Breakpoint value in progressive ratio session0.60.61.40.9-1.2-0.4-0.9-0.70.70.8-0.60.5
Number of licking bursts0.81.01.6-1.11.20.50.71.0-1.0-1.01.30.8
Context. condit. distance diff. score1.11.34.1-2.01.80.50.80.9-0.9-0.80.90.7
Locomotion velocity, session 12.42.63.6-1.91.91.41.91.7-1.7-1.61.31.0
Locomotion distance, session 13.74.85.8-1.71.72.42.42.4-2.4-2.32.22.1
Locomotion velocity, session 20.50.61.6-1.31.10.30.40.6-0.6-0.50.70.6
Locomotion distance, session 20.81.11.5-1.11.01.21.21.0-1.0-1.00.81.1
Locomotion velocity, session 30.70.91.6-0.91.30.00.80.9-0.9-1.21.1-0.8
Locomotion distance, session 32.22.43.7-1.31.71.21.51.7-1.7-1.91.90.6
Stereotopy head waving bouts, day 30.80.92.3-0.50.3-1.4-0.9-0.90.90.7-0.7-1.5
Stereotopy head waving duration, day 30.10.10.5-0.70.5-0.3-0.1-0.20.20.3-0.4-0.4
Locomotion velocity, session 70.40.40.9-0.80.80.80.90.5-0.5-0.70.20.0
Locomotion distance, session 71.31.72.7-1.51.41.61.51.1-1.1-1.30.80.9
Stereotopy head waving bouts, day 70.30.40.6-0.40.8-0.20.40.6-0.6-0.80.8-0.7
Stereotopy head waving duration, day 70.20.31.60.20.2-0.8-0.2-0.00.0-0.20.2-1.3
Locomotion velocity, session 80.70.94.5-2.11.7-0.10.40.4-0.4-0.20.20.1
Locomotion distance, session 81.52.25.4-2.32.11.11.21.3-1.3-1.31.31.1
Degree of sensitization distance1.21.22.80.1-0.8-0.5-1.0-1.41.41.4-1.7-0.1
Degree of sensitization stereotypy0.80.81.7-0.40.90.40.91.1-1.1-1.21.3-0.0
Conditioned locomotion3.33.95.71.2-1.4-2.4-2.3-2.22.22.1-1.9-1.8
Cocaine response after cond. corrected0.50.60.80.8-0.8-0.9-0.9-0.80.80.8-0.7-0.7
Cocaine response after cond. not corrected0.40.40.90.1-0.1-0.9-0.8-0.70.70.6-0.5-0.8
Cocaine response before conditioning0.30.31.6-1.31.1-0.00.20.1-0.1-0.20.1-0.3
Saline control response2.53.36.32.5-2.5-1.1-1.7-1.71.71.7-1.7-1.2
Bone: connectivity density0.10.10.7-0.1-0.10.60.40.2-0.2-0.1-0.10.8
Bone: cortical apparent density0.40.51.51.2-1.1-0.3-0.7-0.60.60.5-0.4-0.5
Bone: cortical area0.00.10.2-0.00.20.10.40.2-0.2-0.40.1-0.3
Bone: cortical porosity0.91.01.9-0.91.11.01.41.1-1.1-1.10.70.1
Bone: cortical porosity0.70.71.4-1.01.10.91.20.8-0.8-0.80.30.1
Bone: cortical thickness0.71.12.00.8-0.31.41.31.1-1.1-1.41.00.4
Bone: cortical thickness0.50.62.61.6-1.50.0-0.3-0.30.30.3-0.3-0.1
Bone: cortical tissue density0.40.51.31.2-1.0-0.5-0.8-0.70.70.6-0.5-0.6
Condit. Reinf. active minus inactive responses0.20.31.0-0.40.11.00.60.3-0.3-0.1-0.10.8
Condit. Reinf. active-inactive response ratio0.40.41.00.9-1.0-0.1-0.6-0.70.70.7-0.70.2
Condit. Reinf. active responses0.10.10.30.2-0.40.50.2-0.10.10.3-0.50.1
Condit. Reinf. inactive responses0.10.10.30.4-0.40.50.40.1-0.10.0-0.20.1
Incentive salience index mean0.30.30.8-0.90.70.70.70.4-0.4-0.30.10.4
Condit. Reinf. lever presses0.30.41.2-1.10.90.40.70.5-0.5-0.50.20.1
Condit. Reinf. active minus inactive responses0.30.31.2-1.10.80.60.40.3-0.3-0.20.20.7
Condit. Reinf. active-inactive response ratio0.10.10.7-0.80.50.2-0.0-0.10.10.1-0.10.3
Condit. Reinf. active responses0.30.41.2-1.10.80.70.60.5-0.5-0.40.40.8
Condit. Reinf. inactive responses0.00.00.1-0.0-0.0-0.10.10.0-0.00.0-0.0-0.3
Condit. Reinf. lever presses1.62.14.9-1.11.02.01.31.3-1.3-1.11.22.2
Condit. Reinf. lever reinforcers received0.81.11.9-1.41.11.31.00.9-0.9-0.80.81.3
Conditioned reinforcement - actives0.20.20.7-0.00.50.20.70.1-0.1-0.50.0-0.8
Conditioned reinforcement - inactives0.40.51.0-0.30.70.70.30.7-0.7-1.00.90.3
Conditioned locomotion0.30.30.80.20.00.10.1-0.80.80.4-0.9-0.7
Patch foraging indifference point 0 sec0.50.72.81.7-1.3-0.5-0.6-0.50.50.4-0.4-0.8
Patch foraging indifference point AUC0.50.62.3-1.51.4-0.00.10.5-0.5-0.40.60.1
Delay disc. indifference point, 0s delay0.00.00.1-0.20.20.20.20.1-0.1-0.30.10.1
Delay disc. indifference point, 16s delay0.10.10.40.00.30.30.70.2-0.2-0.40.1-0.5
Delay disc. indifference point, 2s delay0.10.10.2-0.40.10.50.2-0.20.20.2-0.30.5
Delay disc. indifference point, 24s delay0.80.82.50.7-0.4-0.5-0.2-1.01.00.8-1.1-1.6
Delay disc. indifference point, 4s delay0.80.81.30.4-0.5-1.0-1.1-1.11.10.9-0.8-1.0
Delay disc. indifference point, 8s delay0.90.91.70.5-0.4-0.8-0.6-1.31.31.0-1.1-1.3
Indifference point function ln k0.50.71.2-0.70.80.70.90.8-0.8-1.10.90.5
Indifference point function log k0.50.71.2-0.70.80.70.90.8-0.8-1.10.90.5
Patch foraging total patch changes 0 sec0.40.72.71.6-1.2-0.4-0.6-0.50.50.3-0.3-0.8
Patch foraging total patch changes 12 sec0.10.20.60.30.00.2-0.10.4-0.4-0.70.80.1
Patch foraging total patch changes 18 sec1.01.32.71.7-1.4-0.9-1.6-1.11.10.7-0.4-1.1
Patch foraging total patch changes 24 sec0.20.30.90.9-0.70.70.10.4-0.4-0.30.40.3
Patch foraging total patch changes 6 sec0.20.31.61.3-0.9-0.1-0.5-0.20.20.3-0.1-0.4
Patch foraging time to switch 0 sec2.43.67.22.7-2.7-1.4-1.7-1.71.71.9-1.7-1.1
Patch foraging water rate 0 sec0.30.51.0-0.61.00.80.60.5-0.5-1.00.80.2
Patch foraging water rate 12 sec0.50.82.3-0.60.90.80.50.7-0.7-1.31.50.3
Patch foraging water rate 18 sec0.10.10.30.5-0.40.50.40.1-0.10.1-0.30.4
Patch foraging water rate 24 sec0.50.61.8-0.50.80.60.40.8-0.8-1.11.30.4
Patch foraging water rate 6 sec0.50.71.3-0.80.90.70.70.8-0.8-1.11.10.4
Seeking ratio, delayed vs. immediate footshock0.10.10.6-0.1-0.1-0.8-0.7-0.10.10.20.2-0.1
Distance traveled before self-admin0.80.82.50.0-0.1-1.6-1.5-0.80.80.6-0.1-1.0
Distance traveled after self-admin0.91.02.80.4-0.7-1.5-1.7-1.01.00.8-0.5-0.5
Extensor digitorum longus weight0.10.52.0-1.41.20.30.40.4-0.4-0.50.50.5
Bone: elastic displacement0.70.71.5-0.50.71.11.20.9-0.9-1.10.70.0
Bone: elastic work0.10.10.30.3-0.20.50.40.1-0.1-0.2-0.2-0.2
Bone: endosteal estimation3.16.610.10.6-1.1-3.2-2.9-3.03.03.0-2.9-2.3
Bone: endosteal perimeter1.63.26.10.1-0.4-2.5-2.2-2.02.02.0-1.7-1.6
Epididymis fat weight1.63.813.53.7-3.1-0.7-1.1-1.11.11.3-1.3-1.8
Delta time in closed arm before/after self-admin0.80.81.90.8-0.7-0.9-0.8-0.80.80.6-0.8-1.4
Delta time in open arm before/after self-admin0.30.31.1-0.1-0.00.80.50.3-0.3-0.30.41.0
Diff in mean of infusions in LGA sessions0.10.10.70.2-0.40.4-0.1-0.00.00.4-0.10.8
Delay discount exponential model param0.20.20.7-0.0-0.00.20.00.5-0.5-0.40.50.8
Extinction: sum of active levers before priming0.10.10.2-0.10.10.30.20.3-0.3-0.40.40.4
Active lever presses in extinction session 61.21.22.41.6-1.50.2-0.2-1.11.11.0-1.4-0.3
Bone: final force3.75.97.92.8-2.6-2.3-2.2-2.42.42.2-2.4-2.4
Bone: final moment2.74.45.92.4-2.3-1.9-1.9-2.12.11.9-2.1-2.1
Food consumed during 24 hour testing period2.73.34.51.4-1.9-1.6-2.1-2.02.02.1-1.9-0.9
Glucose1.32.07.0-2.62.40.51.11.0-1.0-1.00.60.3
Heart weight2.63.75.3-2.01.82.12.32.0-2.0-1.51.42.0
Delay discount hyperbolic model param0.10.10.40.1-0.10.10.00.5-0.5-0.30.40.6
Intermittent access intake day 1-15 change0.50.51.30.4-0.5-1.1-0.9-0.60.60.5-0.5-1.0
Intermittent access intake escalation1.11.12.50.4-0.6-1.6-1.3-1.01.00.9-0.8-1.3
Intermittent access intake escalation 20.20.20.9-0.90.8-0.40.20.4-0.4-0.10.1-0.1
Intermitt. access day 1 inactive lever presses0.60.71.5-0.90.8-0.20.10.9-0.9-1.11.20.3
Intermitt. access day 15 inactive lever presses0.70.72.10.3-0.3-1.4-1.1-0.60.60.6-0.4-1.4
Intermitt. access escalation Index0.40.30.8-0.50.30.20.00.7-0.7-0.70.90.5
Intermittent access day 1 total infusions0.80.92.4-0.30.81.51.50.6-0.6-1.20.60.6
Intermittent access day 15 total infusions0.00.10.20.20.10.20.30.0-0.0-0.40.1-0.3
Intermittent access terminal intake (last 3 days)0.10.10.30.10.30.20.5-0.00.0-0.40.0-0.5
Intermittent access total infusions0.30.30.90.10.30.90.90.2-0.2-0.80.20.2
Intermittent access day 1 locomotion0.10.10.3-0.10.3-0.1-0.4-0.50.5-0.20.1-0.4
Intermittent access day 15 total locomotion3.94.26.31.1-1.0-2.3-2.2-2.52.51.9-1.8-2.5
Intermittent access total locomotion1.92.14.10.8-0.7-1.3-1.6-2.02.01.2-1.3-1.5
Intermittent access standard deviation1.11.12.01.4-1.2-1.2-1.2-0.90.90.8-0.8-1.0
Left kidney weight1.64.49.31.0-0.8-2.4-2.1-2.52.51.5-1.9-3.1
Right kidney weight2.15.910.50.7-0.7-3.0-2.8-2.92.91.8-2.2-3.2
Cocaine induced anxiety0.20.20.4-0.60.4-0.7-0.60.3-0.3-0.30.70.1
Post-drug Anxiety0.20.20.8-0.3-0.1-0.5-0.9-0.40.40.30.20.4
Baseline Anxiety0.40.40.60.7-0.80.60.0-0.60.60.7-0.70.6
Tail length0.82.34.6-2.21.8-1.8-1.2-1.31.30.2-0.6-2.1
Length with tail1.34.610.0-0.80.6-2.6-2.1-2.62.61.4-2.1-3.2
Length without tail1.63.55.30.9-1.0-1.8-1.6-2.32.31.9-2.3-2.2
Times rat made contact with spout0.91.02.50.1-0.11.60.90.9-0.9-0.91.01.6
Lifetime Intake0.10.10.40.20.20.60.6-0.20.2-0.4-0.1-0.2
Liver weight, left4.26.610.60.2-0.6-3.2-3.1-3.03.02.4-2.3-3.3
Liver weight, right1.93.25.8-2.31.9-2.4-1.9-1.61.60.7-0.6-2.2
Locomotor activity0.20.30.8-0.40.5-0.6-0.9-0.20.2-0.70.8-0.4
Locomotor testing distance0.10.20.80.2-0.1-0.2-0.40.3-0.3-0.60.90.2
Locomotor testing rearing0.91.42.80.8-0.9-1.6-1.7-1.11.11.2-0.9-1.2
Locomotion in novel chamber0.91.11.9-0.20.61.11.41.2-1.2-1.20.91.2
Locomotion in novel chamber post-restriction1.72.02.51.5-1.5-1.3-1.2-1.41.41.5-1.5-1.6
Fecal boli incidents, locomotor time 10.50.50.90.8-0.9-0.1-0.4-0.90.90.9-0.9-0.0
Change in fecal boli incidents, locomotor task0.10.10.2-0.40.2-0.2-0.4-0.20.2-0.20.30.3
Time >=10cm from walls, locomotor time 13.63.75.01.9-2.1-2.2-2.2-1.81.82.1-1.6-1.4
Bouts of movement, locomotor time 10.10.20.4-0.60.4-0.2-0.5-0.10.1-0.30.50.4
Total resting periods, locomotor time 10.20.20.5-0.60.3-0.4-0.7-0.40.40.10.10.1
Rest time, locomotor task time 10.30.31.1-1.11.00.10.60.4-0.4-0.40.40.1
Distance moved, locomotor task time 10.80.91.81.3-1.3-0.7-0.8-0.70.71.0-0.9-0.6
Vertical activity count, locomotor time 14.34.56.92.6-2.6-1.6-2.2-2.22.22.3-2.1-0.9
Time >=10cm from walls, locomotor time 25.45.77.62.5-2.5-2.2-2.0-2.32.32.7-2.7-2.0
Bouts of movement, locomotor time 20.70.81.9-0.60.1-1.3-1.4-1.01.00.9-0.6-0.4
Total resting periods, locomotor time 20.40.41.6-1.20.7-0.7-0.9-0.40.40.30.00.2
Rest time, locomotor task time 20.40.41.5-1.21.0-0.3-0.10.4-0.4-0.60.80.1
Distance moved, locomotor task time 23.13.65.22.3-2.1-1.3-1.2-1.91.92.1-2.3-1.7
Vertical activity count, locomotor time 23.84.16.22.2-2.1-1.3-1.6-2.22.22.3-2.5-1.3
Light reinforcement 11.93.45.52.0-1.8-2.3-2.2-1.61.61.8-1.4-1.7
Light reinforcement 22.63.55.81.5-1.7-2.4-1.9-1.61.62.3-2.1-1.6
Bone: marrow area3.27.010.40.7-1.2-3.2-2.9-3.03.03.0-3.0-2.4
Bone: maximum diameter0.20.41.6-1.31.0-0.7-0.2-0.30.30.1-0.3-0.5
Bone: maximum force0.91.52.31.4-1.2-1.1-0.9-1.21.21.0-1.4-1.5
Bone: maximum moment0.50.91.31.0-0.9-0.7-0.6-1.01.00.7-1.2-1.2
Mean time between licks in bursts1.82.58.1-2.92.70.30.81.1-1.1-1.11.40.7
Mean num. licks in bursts0.20.30.90.8-0.90.60.0-0.20.20.3-0.40.4
Cd content in liver1.71.94.42.1-1.9-0.6-0.8-1.21.21.3-1.6-1.2
Co content in liver2.63.16.62.6-2.3-1.4-1.5-1.51.51.6-1.5-1.5
Cu content in liver2.12.65.3-0.10.32.31.81.7-1.7-1.71.52.0
Fe content in liver1.01.24.70.6-0.3-1.5-0.7-0.90.90.8-1.0-2.2
K content in liver2.12.14.0-2.01.91.11.31.3-1.3-1.51.40.9
Mg content in liver4.74.89.9-3.12.91.71.91.9-1.9-2.01.91.8
Mn content in liver1.01.15.8-2.41.9-0.20.10.2-0.2-0.20.30.3
Na content in liver0.10.10.3-0.50.6-0.10.00.2-0.2-0.30.50.0
Rb content in liver0.20.30.80.3-0.5-0.2-0.3-0.50.50.7-0.9-0.5
Se content in liver6.17.517.4-4.23.91.82.42.4-2.4-2.52.41.6
Sr content in liver0.40.40.70.8-0.90.1-0.3-0.50.50.7-0.80.2
Zn content in liver0.10.20.4-0.60.60.10.40.1-0.1-0.2-0.2-0.6
Bone: minimum diameter0.71.32.10.1-0.3-1.5-1.2-1.31.31.2-1.3-1.2
Time in familiar zone, hab. session 10.20.20.40.10.00.60.60.5-0.5-0.40.30.2
Time in novel zone, hab. session 10.10.10.3-0.30.2-0.5-0.3-0.20.20.3-0.2-0.3
Total zone transitions, hab. session 14.15.87.9-1.51.92.32.52.7-2.7-2.82.82.0
Total locomotion distance, hab. session 13.55.06.5-1.92.12.02.32.5-2.5-2.52.61.5
Locomotion velocity, hab. session 13.55.06.7-1.92.12.02.32.5-2.5-2.62.51.5
Time in familiar zone, hab. session 20.20.21.0-0.30.20.2-0.20.3-0.3-0.40.91.0
Time in novel zone, hab. session 20.60.61.80.8-0.8-0.3-0.1-0.70.70.8-1.3-1.1
Total zone transitions, hab. session 21.01.42.9-0.91.10.70.91.3-1.3-1.41.70.8
Total locomotion distance, hab. session 23.04.07.2-1.51.81.51.72.2-2.2-2.32.71.7
Locomotion velocity, hab. session 23.95.28.8-1.92.21.81.92.5-2.5-2.63.01.9
Novel to familiar place preference ratio0.10.10.30.3-0.00.30.60.3-0.3-0.40.1-0.2
Novelty place preference0.10.10.30.10.10.20.50.3-0.3-0.40.1-0.2
Time in novel zone, NPP test0.00.00.10.10.10.10.40.1-0.1-0.2-0.1-0.3
Total zone transitions, NPP test2.53.64.1-1.81.91.81.92.0-2.0-2.02.01.8
Total locomotion distance, NPP test1.11.62.4-0.80.81.51.31.3-1.3-1.31.31.4
Locomotion velocity, NPP test1.72.43.2-0.91.01.81.51.6-1.6-1.61.71.8
Intraocular pressure0.40.51.50.4-0.3-0.9-0.7-0.60.60.5-0.7-1.2
Delta distance traveled before/after self-admin0.10.10.40.4-0.50.40.1-0.10.10.2-0.40.6
Delta ambulatory time before/after self-admin0.10.10.40.2-0.40.3-0.1-0.10.10.2-0.30.6
Parametrial fat weight1.53.05.21.6-1.4-2.3-1.9-1.71.71.5-1.0-2.3
Pavlov. Cond. lever latency4.15.28.62.8-2.9-1.7-2.5-2.32.32.4-1.9-0.9
Pavlov. Cond. magazine entry latency2.53.37.6-2.72.51.31.81.6-1.6-1.61.31.1
Pavlov. Cond. change in total contacts0.70.71.9-1.31.40.20.90.8-0.8-0.70.6-0.6
Pavlov. Cond. index score3.44.38.4-2.92.91.52.22.0-2.0-2.01.60.8
Pavlov. Cond. latency score3.24.07.9-2.82.81.32.11.9-1.9-2.01.60.7
Pavlov. Cond. lever contacts3.23.86.0-2.42.41.62.31.9-1.9-2.01.50.8
Pavlov. Cond. magazine entry number2.73.46.52.5-2.4-1.4-1.8-1.71.71.7-1.6-1.3
Pavlov. Cond. intertrial magazine entries0.70.82.21.5-1.50.2-0.4-0.70.70.7-0.9-0.3
Pavlov. Cond. lever-magazine prob. diff.3.64.58.2-2.82.91.52.42.0-2.0-2.11.60.8
Pavlov. Cond. response bias4.15.09.2-3.02.91.82.42.1-2.1-2.11.71.3
Pavlov. Cond. lever latency1.31.73.31.1-1.1-1.8-1.5-1.31.31.2-1.0-1.4
Pavlov. Cond. magazine entry latency0.70.82.00.1-0.5-0.6-0.8-1.11.11.2-1.4-0.6
Pavlov. Cond. change in total contacts0.30.51.4-0.50.31.20.70.5-0.5-0.40.31.0
Pavlov. Cond. index score0.10.20.5-0.60.40.70.40.2-0.2-0.1-0.10.5
Pavlov. Cond. latency score0.10.10.2-0.50.30.50.20.1-0.10.1-0.20.3
Pavlov. Cond. lever contacts0.70.92.4-0.40.41.51.11.0-1.0-0.90.71.1
Pavlov. Cond. magazine entry number0.50.61.2-0.40.70.40.60.8-0.8-1.01.10.3
Pavlov. Cond. intertrial magazine entries0.60.72.6-1.61.3-0.00.10.5-0.5-0.41.00.8
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.30.20.40.2-0.00.00.2-0.30.3
Pavlov. Cond. response bias0.40.61.5-0.70.61.21.00.6-0.6-0.50.20.8
Time in closed arm before self-admin0.10.10.20.1-0.20.50.30.1-0.10.0-0.10.4
Time in closed arm after self-admin0.10.10.30.4-0.20.20.30.0-0.0-0.1-0.2-0.5
Time in open arm before self-admin0.70.71.3-1.11.10.60.90.8-0.8-0.80.60.6
Time in open arm after self-admin0.91.02.8-1.10.91.11.00.7-0.7-0.70.71.7
Bone: periosteal estimation1.22.54.20.4-0.6-2.1-1.7-1.81.81.7-1.8-1.7
Bone: periosteal perimeter0.60.91.80.3-0.4-1.3-1.3-1.11.11.0-0.8-0.9
Bone: post-yield work0.20.31.30.1-0.3-0.5-0.2-0.60.60.7-1.1-0.4
Progressive ratio test 1 active lever presses0.10.10.60.00.30.80.2-0.10.1-0.30.20.1
Progressive ratio test 1 breakpoint0.10.10.60.00.20.80.3-0.10.1-0.40.20.2
Progressive ratio test 1 inactive lever presses0.40.41.01.0-0.7-0.7-0.7-0.40.40.3-0.3-0.9
Progressive ratio test 2 active lever presses0.00.00.00.2-0.10.2-0.2-0.10.1-0.10.2-0.0
Progressive ratio test 2 breakpoint0.10.10.20.10.10.3-0.00.1-0.1-0.40.40.1
Progressive ratio test 2 inactive lever presses0.20.30.6-0.60.80.50.50.5-0.5-0.50.50.3
Incentive Sensitization - Responses0.70.71.8-0.40.50.50.21.0-1.0-1.11.30.9
Incentive Sensitization - Breakpoint0.40.51.4-0.30.40.2-0.00.8-0.8-0.91.20.6
Sum of active levers in priming session hrs 5-60.50.51.4-0.30.41.01.20.7-0.7-0.60.30.5
Progressive ratio4.04.66.21.9-2.0-2.5-2.4-2.12.12.1-1.6-2.4
Food seeking constrained by brief footshock0.20.30.90.9-0.80.30.1-0.30.30.5-0.5-0.0
Seeking ratio, punishment vs. effort2.63.24.8-1.31.52.22.11.9-1.9-1.71.41.8
Retroperitoneal fat weight0.72.44.01.2-1.1-1.7-1.5-1.41.41.6-1.7-2.0
Reaction time number correct1.01.52.21.5-1.5-1.0-1.3-1.31.31.1-0.8-1.1
Reaction time mean minus median0.40.52.0-1.41.1-0.8-0.2-0.00.00.2-0.4-0.3
Reaction time mean minus median AUC0.30.31.2-1.10.7-0.50.3-0.00.00.5-0.9-0.2
Reaction time num false alarms0.40.51.4-1.01.2-0.2-0.40.2-0.2-0.71.10.2
Reaction time num false alarms AUC0.81.02.4-1.41.50.30.10.7-0.7-1.11.50.8
Reaction time trials correct on left1.01.52.21.5-1.5-1.0-1.3-1.31.31.1-0.8-1.1
Reaction time trials on left1.11.52.21.5-1.5-1.1-1.4-1.31.31.2-0.9-1.1
Reaction time mean0.30.41.5-0.3-0.1-0.70.1-0.10.11.0-1.2-0.2
Reaction time mean AUC0.50.62.4-0.1-0.3-1.0-0.1-0.30.31.4-1.6-0.5
Median of all reaction times0.30.51.70.2-0.5-0.7-0.1-0.20.21.2-1.3-0.3
Reaction time omissions0.10.20.8-0.60.4-0.9-0.40.0-0.00.5-0.2-0.2
Reaction time false alarm rate2.02.85.5-2.22.31.01.01.4-1.4-1.71.91.3
Reaction time premature initiation rate0.20.20.50.3-0.20.20.50.7-0.7-0.20.30.7
Reaction time premature initiations0.30.51.71.3-1.2-0.5-0.4-0.30.30.6-0.4-0.1
Std. dev. reaction times0.30.41.8-1.30.9-0.60.10.0-0.00.4-0.7-0.2
Reaction time trials completed1.11.52.21.5-1.5-1.1-1.4-1.31.31.2-0.9-1.1
Reaction time trials AUC1.11.62.41.5-1.5-1.1-1.4-1.31.31.2-0.9-1.1
Run reversals in cocaine runway, females0.30.30.80.9-0.60.50.2-0.50.50.1-0.8-0.3
Run reversals in cocaine runway, males0.50.52.0-1.41.3-0.20.40.1-0.1-0.50.2-0.4
Latency to leave start box in cocaine runway0.50.61.0-0.50.50.80.91.0-1.0-0.60.70.6
Latency to leave start box in cocaine runway, F0.40.50.9-0.50.40.70.80.9-0.9-0.50.70.5
Latency to leave start box in cocaine runway, M0.30.30.5-0.30.40.30.50.7-0.7-0.60.70.2
Std. dev. time between licks in bursts2.02.47.6-2.72.8-0.10.81.1-1.1-1.31.4-0.2
Total sessions with >9 infusions0.10.10.3-0.00.30.50.1-0.40.4-0.2-0.00.1
Short access day 1 total inactive lever presses0.20.20.5-0.70.70.50.50.1-0.1-0.30.00.0
Short access day 10 total inactive lever presses0.50.61.3-0.80.4-1.1-1.00.5-0.5-0.41.0-0.1
Short access day 1 total infusions1.51.63.0-0.91.31.71.60.9-0.9-1.51.11.0
Short access day 10 total infusions0.00.00.10.3-0.10.1-0.1-0.40.4-0.1-0.00.0
Short access total infusions0.10.10.5-0.00.30.70.7-0.10.1-0.50.0-0.0
Short access day 1 locomotion0.60.61.5-0.80.90.40.20.7-0.7-1.21.20.5
Short access day 10 total locomotion0.50.61.6-1.31.10.1-0.20.3-0.3-1.01.10.5
Short access total locomotion0.20.20.6-0.20.2-0.3-0.8-0.70.70.1-0.0-0.2
One hour access (0.3 mA shock)0.91.11.9-1.01.01.01.00.9-0.9-1.41.10.8
Compulsive drug intake0.90.92.4-0.70.51.21.00.9-0.9-0.90.61.6
One hour access (shock baseline)0.10.10.4-0.20.3-0.20.1-0.40.40.1-0.3-0.6
Social response proportion0.00.00.1-0.20.2-0.1-0.1-0.30.30.0-0.10.2
Social responses0.10.10.3-0.20.3-0.2-0.40.2-0.2-0.20.50.3
Social time0.60.82.6-1.61.3-0.5-0.20.5-0.5-0.61.10.5
Soleus weight0.51.56.9-2.62.2-1.0-0.2-0.30.3-0.0-0.1-0.9
Bone: stiffness0.91.41.61.3-1.2-1.2-1.1-1.21.21.0-1.1-1.1
Tibialis anterior weight0.31.02.3-0.40.41.20.81.0-1.0-1.01.11.5
Time to tail flick, vehicle, before self-admin1.11.24.4-0.0-0.1-2.1-1.6-0.60.60.9-0.2-1.4
Time to tail flick, vehicle, after self-admin0.00.00.10.1-0.3-0.1-0.4-0.20.20.00.10.2
Time to tail flick, test, before self-admin0.40.41.4-0.30.4-0.1-0.20.7-0.7-0.71.2-0.2
Time to tail flick, test, after self-admin0.30.31.4-1.21.0-0.1-0.10.2-0.2-0.40.6-0.3
Delta time to tail flick, vehicle, before/after SA0.70.72.80.3-0.31.71.10.3-0.3-0.50.11.1
Delta time to tail flick, test, before/after SA0.80.71.20.5-0.6-0.8-0.8-1.11.10.9-0.9-0.7
Tibia length1.95.49.70.4-0.8-3.1-2.5-2.52.52.4-2.4-2.9
Ambulatory time before self-admin0.30.31.10.0-0.0-1.1-0.8-0.40.40.30.0-0.8
Ambulatory time after self-admin0.30.31.10.2-0.4-0.9-1.1-0.50.50.4-0.2-0.1
Bone: tissue strength0.30.31.11.0-0.90.1-0.2-0.40.40.3-0.6-0.2
Total heroin consumption0.00.10.20.1-0.2-0.1-0.2-0.20.20.3-0.10.5
Bone: trabecular number0.50.91.7-0.20.31.31.10.9-0.9-0.90.81.3
Bone: trabecular spacing1.62.12.91.0-1.0-1.7-1.6-1.51.51.6-1.4-1.5
Bone: trabecular thickness0.20.20.50.2-0.3-0.3-0.1-0.40.40.4-0.7-0.7
Bone: trabecular tissue density0.20.30.9-0.90.90.00.50.3-0.3-0.40.0-0.5
Water consumed over 24 hours0.20.20.9-0.2-0.10.80.20.2-0.2-0.10.21.0
Number of responses in last shaping day3.23.36.4-1.82.12.22.51.8-1.8-1.81.01.1