Hub : Genes

Pitpnc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression Pitpnc1 0.04 0.02 1.2e-03 0 0.02 0.01 0.01 2.4e-01 1.2e-03 8.3e-03 2.0e-02
2 Liver gene expression Pitpnc1 0.11 0.05 8.9e-09 0.04 0.05 0.06 0.06 5.6e-05 1.9e-06 4.0e-07 8.4e-07
3 IL gene expression Pitpnc1 0.51 0.15 1.5e-04 0.08 0.11 0.12 0.13 5.2e-03 1.4e-03 7.5e-04 5.3e-04
4 Brain gene expression Pitpnc1 0.2 0.1 1.5e-07 0.04 0.07 0.08 0.07 6.7e-05 5.2e-07 8.6e-08 3.9e-07
5 RMTg intron excision ratio chr10_92673609_92683748 0.21 0.12 5.5e-03 0.1 0.03 0.08 0.16 1.4e-03 5.1e-02 4.0e-03 6.1e-05
6 RMTg intron excision ratio chr10_92668071_92673491 0.18 0.1 8.5e-03 0.06 0.03 0.06 0.05 9.7e-03 5.0e-02 1.1e-02 2.1e-02
7 LHb gene expression Pitpnc1 0.29 0.13 7.2e-03 0.1 0.09 0.05 0.11 2.6e-03 4.3e-03 2.6e-02 1.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.10.30.40.5-0.20.10.50.5-0.1
Area under the delay curve0.91.41.9-0.9-0.9-1.31.31.31.4-1.0
BMI with tail0.82.95.1-1.60.9-1.41.02.32.02.2
BMI without tail0.73.97.0-1.41.9-1.41.12.62.42.4
Body weight0.73.16.10.02.5-0.50.32.52.41.8
Weight adjusted by age0.20.71.1-0.8-1.0-0.91.00.50.4-1.1
Bone surface1.53.08.62.92.31.9-1.6-0.3-0.2-0.5
Bone volume0.71.33.92.01.90.9-0.80.30.4-0.4
Breakpoint value in progressive ratio session0.61.02.2-0.1-1.30.7-0.1-1.4-1.5-0.9
Number of licking bursts0.10.20.50.40.20.2-0.1-0.7-0.7-0.2
Context. condit. distance diff. score0.00.00.1-0.1-0.1-0.40.1-0.2-0.2-0.2
Locomotion velocity, session 10.20.20.60.60.50.7-0.00.50.5-0.1
Locomotion distance, session 10.30.41.10.20.10.20.71.01.0-0.4
Locomotion velocity, session 22.32.75.01.90.82.2-1.1-2.0-2.0-0.8
Locomotion distance, session 20.40.51.00.5-0.40.80.1-0.9-0.9-1.0
Locomotion velocity, session 31.21.33.2-1.0-1.6-0.81.80.20.1-1.4
Locomotion distance, session 30.50.52.40.4-0.5-0.00.4-0.6-0.6-1.5
Stereotopy head waving bouts, day 31.11.32.1-1.4-1.5-1.01.31.01.0-0.1
Stereotopy head waving duration, day 31.31.63.0-1.4-1.7-1.11.51.01.0-0.6
Locomotion velocity, session 70.10.10.7-0.10.10.4-0.3-0.1-0.10.9
Locomotion distance, session 70.10.10.30.10.6-0.1-0.4-0.2-0.20.2
Stereotopy head waving bouts, day 71.41.66.4-0.7-2.5-0.31.0-0.9-1.0-1.4
Stereotopy head waving duration, day 71.82.38.2-0.6-2.9-0.10.9-1.3-1.4-1.6
Locomotion velocity, session 80.91.02.31.40.71.5-1.1-0.8-0.8-0.1
Locomotion distance, session 80.20.30.60.80.40.7-0.2-0.7-0.7-0.4
Degree of sensitization distance0.50.61.60.10.90.4-0.90.50.61.3
Degree of sensitization stereotypy1.71.94.9-0.4-2.2-0.00.8-1.6-1.7-1.5
Conditioned locomotion0.10.10.50.10.40.0-0.5-0.1-0.20.7
Cocaine response after cond. corrected0.10.10.4-0.2-0.6-0.2-0.0-0.1-0.1-0.5
Cocaine response after cond. not corrected0.71.01.90.6-1.00.7-0.3-1.4-1.4-1.1
Cocaine response before conditioning1.21.42.31.0-1.01.00.3-1.5-1.5-1.5
Saline control response0.20.30.9-0.30.20.3-0.3-0.6-0.70.9
Bone: connectivity density0.20.41.11.10.60.7-0.70.20.3-0.3
Bone: cortical apparent density4.06.312.3-3.5-2.1-3.52.62.01.90.3
Bone: cortical area0.40.61.60.10.9-0.61.20.80.8-0.0
Bone: cortical porosity4.34.68.22.91.52.7-1.6-2.5-2.4-0.7
Bone: cortical porosity1.82.04.32.11.21.6-0.5-1.5-1.4-1.1
Bone: cortical thickness6.110.221.8-4.2-2.6-4.04.72.11.8-0.3
Bone: cortical thickness1.62.04.8-2.2-1.2-1.72.10.30.10.4
Bone: cortical tissue density3.86.012.0-3.5-2.1-3.42.52.01.80.4
Condit. Reinf. active minus inactive responses1.21.43.82.01.01.3-0.3-1.0-0.8-1.2
Condit. Reinf. active-inactive response ratio0.80.91.91.40.51.0-0.6-1.1-1.0-0.8
Condit. Reinf. active responses1.31.65.02.21.41.6-0.4-0.7-0.6-1.0
Condit. Reinf. inactive responses0.40.51.21.11.00.8-0.00.50.6-0.4
Incentive salience index mean1.11.43.21.81.01.4-0.4-1.2-1.1-0.8
Condit. Reinf. lever presses0.40.61.60.70.40.8-0.2-1.2-1.3-0.0
Condit. Reinf. active minus inactive responses1.72.67.42.71.21.5-0.4-1.4-1.2-1.9
Condit. Reinf. active-inactive response ratio1.21.94.42.11.11.4-0.8-1.4-1.3-1.1
Condit. Reinf. active responses1.82.68.73.01.71.7-0.6-0.9-0.7-1.3
Condit. Reinf. inactive responses0.40.61.61.31.20.60.30.40.4-0.3
Condit. Reinf. lever presses1.01.43.31.81.30.9-0.4-1.4-1.4-0.6
Condit. Reinf. lever reinforcers received1.62.37.72.81.71.6-0.6-0.8-0.7-1.1
Conditioned reinforcement - actives0.10.30.6-0.10.7-0.40.80.50.6-0.0
Conditioned reinforcement - inactives0.10.41.00.61.00.6-0.30.60.50.2
Conditioned locomotion0.30.52.40.51.50.1-0.30.40.40.5
Patch foraging indifference point 0 sec0.51.55.51.12.30.0-0.01.31.40.4
Patch foraging indifference point AUC0.10.20.70.50.80.4-0.10.30.3-0.1
Delay disc. indifference point, 0s delay0.50.61.2-0.8-1.1-0.80.60.60.6-0.4
Delay disc. indifference point, 16s delay1.01.42.2-1.1-0.5-1.51.41.51.5-0.5
Delay disc. indifference point, 2s delay0.50.61.60.10.2-0.50.31.11.3-0.8
Delay disc. indifference point, 24s delay1.11.83.9-0.80.9-1.31.11.92.00.6
Delay disc. indifference point, 4s delay0.80.92.8-0.4-1.7-0.60.9-0.1-0.0-1.4
Delay disc. indifference point, 8s delay1.01.72.3-1.4-1.1-1.51.31.51.5-0.6
Indifference point function ln k0.20.51.3-0.6-0.9-0.91.1-0.1-0.1-0.5
Indifference point function log k0.20.51.3-0.6-0.9-0.91.1-0.1-0.1-0.5
Patch foraging total patch changes 0 sec0.51.44.91.22.20.2-0.11.31.40.3
Patch foraging total patch changes 12 sec1.62.17.81.82.81.2-1.20.60.80.5
Patch foraging total patch changes 18 sec0.20.51.60.91.30.9-0.50.10.10.2
Patch foraging total patch changes 24 sec0.31.12.50.71.60.20.51.51.5-0.2
Patch foraging total patch changes 6 sec0.81.45.41.42.30.6-0.30.91.00.2
Patch foraging time to switch 0 sec0.10.20.4-0.6-0.5-0.0-0.6-0.4-0.50.4
Patch foraging water rate 0 sec0.20.93.60.91.90.2-0.10.90.90.7
Patch foraging water rate 12 sec0.20.82.1-0.9-0.8-1.01.40.80.7-0.1
Patch foraging water rate 18 sec0.10.31.1-0.30.0-0.81.10.30.3-0.3
Patch foraging water rate 24 sec0.10.20.90.1-0.60.00.2-0.3-0.3-1.0
Patch foraging water rate 6 sec0.40.51.2-0.7-0.7-0.61.10.80.7-0.2
Seeking ratio, delayed vs. immediate footshock0.30.50.7-0.8-0.5-0.80.70.80.7-0.0
Distance traveled before self-admin0.51.23.2-0.1-1.80.10.6-0.9-0.9-1.7
Distance traveled after self-admin0.61.12.30.9-0.40.70.0-1.5-1.4-1.5
Extensor digitorum longus weight1.56.110.7-3.0-1.0-1.90.93.33.12.8
Bone: elastic displacement1.01.23.2-1.1-1.6-1.01.80.20.1-0.9
Bone: elastic work0.40.61.1-0.60.3-0.91.00.80.70.6
Bone: endosteal estimation8.220.044.46.75.55.2-5.2-2.6-2.30.4
Bone: endosteal perimeter5.914.536.56.05.04.3-4.2-1.5-1.1-0.1
Epididymis fat weight0.21.12.9-0.81.0-0.8-0.31.11.01.7
Delta time in closed arm before/after self-admin0.10.10.40.10.40.3-0.70.00.00.4
Delta time in open arm before/after self-admin0.70.91.2-0.9-1.1-1.11.00.90.9-0.7
Diff in mean of infusions in LGA sessions0.40.72.3-1.5-1.0-0.80.6-0.2-0.40.7
Delay discount exponential model param0.81.01.80.60.61.1-1.1-1.2-1.30.9
Extinction: sum of active levers before priming0.20.30.6-0.7-0.7-0.80.50.50.40.4
Active lever presses in extinction session 60.20.20.30.60.60.3-0.3-0.4-0.40.0
Bone: final force0.30.52.60.71.60.20.20.20.20.2
Bone: final moment0.30.52.60.81.60.20.20.10.20.1
Food consumed during 24 hour testing period0.51.03.2-0.31.20.2-0.31.00.91.8
Glucose0.81.34.3-1.1-2.1-0.51.1-0.4-0.5-1.3
Heart weight0.91.43.0-1.3-0.6-1.61.71.11.1-0.4
Delay discount hyperbolic model param0.70.91.60.60.61.0-0.9-1.2-1.30.9
Intermittent access intake day 1-15 change0.10.82.00.80.50.8-1.3-0.5-0.51.4
Intermittent access intake escalation0.10.81.70.90.80.8-1.2-0.4-0.41.3
Intermittent access intake escalation 21.11.94.11.31.71.1-1.8-0.3-0.32.0
Intermitt. access day 1 inactive lever presses0.11.02.21.40.71.5-1.1-0.6-0.60.5
Intermitt. access day 15 inactive lever presses0.20.92.20.41.11.0-1.30.20.21.5
Intermitt. access escalation Index0.31.02.6-0.4-1.6-0.20.5-1.2-1.3-0.7
Intermittent access day 1 total infusions0.20.62.70.3-0.1-0.11.10.10.0-1.6
Intermittent access day 15 total infusions0.10.20.50.60.70.10.10.30.30.0
Intermittent access terminal intake (last 3 days)0.50.92.81.41.70.8-0.70.20.30.4
Intermittent access total infusions0.40.51.11.11.00.40.20.30.3-0.8
Intermittent access day 1 locomotion0.20.41.40.71.20.20.5-0.1-0.1-0.7
Intermittent access day 15 total locomotion0.31.14.41.52.10.8-0.6-0.00.00.5
Intermittent access total locomotion1.11.36.21.52.50.6-0.00.10.2-0.1
Intermittent access standard deviation0.10.40.70.80.80.6-0.70.10.20.5
Left kidney weight0.10.51.7-0.5-0.7-0.51.30.0-0.1-0.9
Right kidney weight0.10.92.2-0.8-1.0-1.11.50.20.2-1.0
Cocaine induced anxiety0.20.51.00.3-0.8-0.10.5-0.8-0.8-1.0
Post-drug Anxiety0.20.30.5-0.4-0.7-0.50.7-0.1-0.1-0.7
Baseline Anxiety0.81.42.7-1.70.4-1.20.61.41.31.1
Tail length0.52.410.51.63.21.0-1.00.40.41.2
Length with tail0.52.26.72.12.61.3-1.10.60.80.4
Length without tail0.10.31.00.30.40.1-0.30.91.00.3
Times rat made contact with spout0.60.72.90.90.51.7-0.7-0.5-0.50.5
Lifetime Intake0.40.40.90.71.00.20.60.50.5-0.9
Liver weight, left2.13.68.22.91.72.5-1.6-1.6-1.5-0.4
Liver weight, right0.40.61.9-0.9-1.1-0.41.40.20.1-0.5
Locomotor activity0.40.61.60.50.1-0.11.0-0.8-0.8-1.2
Locomotor testing distance0.20.61.10.6-0.00.20.9-0.9-1.0-1.1
Locomotor testing rearing0.72.55.11.60.61.9-1.1-2.1-2.30.4
Locomotion in novel chamber0.60.81.50.6-0.80.9-0.4-1.0-1.0-1.2
Locomotion in novel chamber post-restriction0.30.92.11.41.11.1-1.10.20.3-0.5
Fecal boli incidents, locomotor time 10.00.10.10.0-0.30.1-0.4-0.00.0-0.4
Change in fecal boli incidents, locomotor task1.11.12.7-0.40.7-0.90.31.51.61.1
Time >=10cm from walls, locomotor time 10.70.91.90.1-1.00.40.1-1.4-1.4-1.0
Bouts of movement, locomotor time 10.60.81.4-1.20.0-0.80.31.00.91.2
Total resting periods, locomotor time 10.70.91.6-1.10.1-0.80.11.21.11.3
Rest time, locomotor task time 10.10.20.5-0.2-0.60.2-0.70.30.30.7
Distance moved, locomotor task time 10.10.20.6-0.20.8-0.0-0.00.30.30.8
Vertical activity count, locomotor time 10.00.10.40.10.60.1-0.10.00.00.5
Time >=10cm from walls, locomotor time 20.51.32.70.4-0.21.3-1.3-1.5-1.60.9
Bouts of movement, locomotor time 20.31.13.0-1.7-0.9-1.00.60.90.71.2
Total resting periods, locomotor time 20.31.13.0-1.7-1.2-1.10.80.80.60.6
Rest time, locomotor task time 21.01.84.8-1.8-2.2-1.41.00.60.6-1.0
Distance moved, locomotor task time 21.11.53.90.61.11.3-1.3-0.8-0.92.0
Vertical activity count, locomotor time 20.81.84.11.21.51.4-1.4-0.7-0.82.0
Light reinforcement 10.73.35.3-2.3-0.7-2.32.22.01.80.5
Light reinforcement 21.43.14.9-1.8-1.0-1.91.92.22.2-0.4
Bone: marrow area8.119.943.76.65.45.2-5.2-2.7-2.30.4
Bone: maximum diameter1.12.37.82.82.21.3-0.8-0.10.1-1.0
Bone: maximum force0.40.93.10.71.8-0.20.61.01.00.1
Bone: maximum moment0.50.93.40.81.8-0.20.50.91.00.2
Mean time between licks in bursts0.10.51.0-0.50.5-0.5-0.31.01.00.9
Mean num. licks in bursts0.10.20.6-0.3-0.10.30.00.80.80.5
Cd content in liver0.60.62.9-0.00.60.3-1.00.00.11.7
Co content in liver0.30.31.6-0.7-1.3-0.30.4-0.1-0.1-0.2
Cu content in liver0.10.10.20.50.40.3-0.40.10.20.3
Fe content in liver1.51.84.21.3-0.20.8-0.3-2.0-2.0-1.4
K content in liver0.30.31.40.5-0.20.20.1-0.4-0.4-1.2
Mg content in liver0.00.00.1-0.3-0.2-0.30.2-0.00.0-0.1
Mn content in liver0.40.52.20.3-0.3-0.30.7-0.3-0.3-1.5
Na content in liver1.01.25.10.3-1.10.00.6-0.8-0.8-2.3
Rb content in liver0.70.81.5-0.2-0.8-0.80.7-1.1-1.0-1.2
Se content in liver2.53.06.3-1.1-2.5-1.52.20.40.4-2.4
Sr content in liver0.50.41.20.00.90.4-0.20.50.51.1
Zn content in liver0.40.51.70.0-1.30.10.60.10.2-1.0
Bone: minimum diameter3.66.920.43.94.52.2-2.6-0.6-0.40.7
Time in familiar zone, hab. session 10.70.82.01.01.40.5-1.20.10.10.8
Time in novel zone, hab. session 10.60.61.5-1.1-1.2-0.41.20.40.3-0.1
Total zone transitions, hab. session 10.20.20.4-0.10.7-0.00.50.60.50.4
Total locomotion distance, hab. session 10.30.41.00.11.00.30.50.70.60.4
Locomotion velocity, hab. session 10.20.31.00.31.00.60.10.40.40.3
Time in familiar zone, hab. session 21.61.83.41.81.21.7-1.5-1.1-1.1-0.2
Time in novel zone, hab. session 21.21.42.2-1.5-1.0-1.41.11.21.30.0
Total zone transitions, hab. session 20.10.10.3-0.20.30.40.20.20.10.5
Total locomotion distance, hab. session 20.70.92.1-0.41.00.00.41.51.41.0
Locomotion velocity, hab. session 20.71.02.5-0.50.9-0.00.51.61.50.9
Novel to familiar place preference ratio0.10.20.60.60.8-0.0-0.00.30.40.3
Novelty place preference0.10.10.30.50.60.00.00.10.20.3
Time in novel zone, NPP test0.10.10.30.60.40.20.0-0.1-0.10.1
Total zone transitions, NPP test0.40.72.1-0.6-0.1-0.61.50.90.8-0.6
Total locomotion distance, NPP test0.30.41.30.41.10.60.00.60.60.3
Locomotion velocity, NPP test0.60.82.2-0.50.7-0.30.91.51.40.2
Intraocular pressure0.71.12.0-0.7-0.8-0.51.31.41.4-0.8
Delta distance traveled before/after self-admin0.10.10.30.10.6-0.10.4-0.4-0.40.0
Delta ambulatory time before/after self-admin0.10.21.10.41.1-0.20.20.10.10.5
Parametrial fat weight0.30.82.20.61.10.6-1.50.50.60.9
Pavlov. Cond. lever latency0.40.51.0-0.5-0.2-0.8-0.60.91.00.7
Pavlov. Cond. magazine entry latency0.60.81.51.21.01.00.1-0.8-0.7-1.0
Pavlov. Cond. change in total contacts0.80.81.71.20.91.30.3-0.9-0.9-0.6
Pavlov. Cond. index score0.60.71.11.00.61.00.4-0.9-0.9-1.0
Pavlov. Cond. latency score0.50.61.10.80.30.90.5-0.9-0.9-1.0
Pavlov. Cond. lever contacts0.60.71.50.70.51.2-0.0-1.2-1.2-0.2
Pavlov. Cond. magazine entry number0.60.71.5-1.0-0.8-0.7-0.30.80.71.2
Pavlov. Cond. intertrial magazine entries0.50.61.10.31.1-0.70.60.91.0-0.5
Pavlov. Cond. lever-magazine prob. diff.0.60.71.31.00.60.90.5-0.8-0.8-1.2
Pavlov. Cond. response bias0.81.01.81.31.11.10.2-1.0-0.9-1.1
Pavlov. Cond. lever latency0.40.61.1-1.0-0.3-0.40.11.01.00.9
Pavlov. Cond. magazine entry latency0.91.23.3-0.7-1.8-0.70.3-1.1-1.2-1.3
Pavlov. Cond. change in total contacts0.71.63.11.6-0.11.0-0.7-1.8-1.7-1.2
Pavlov. Cond. index score0.71.12.70.8-0.40.4-0.2-1.6-1.6-1.3
Pavlov. Cond. latency score1.01.63.60.8-0.70.3-0.1-1.9-1.9-1.6
Pavlov. Cond. lever contacts0.20.30.60.70.30.10.1-0.8-0.8-0.7
Pavlov. Cond. magazine entry number1.51.94.80.72.20.7-0.61.51.51.6
Pavlov. Cond. intertrial magazine entries2.14.611.01.93.31.6-1.91.71.82.3
Pavlov. Cond. lever-magazine prob. diff.0.81.22.70.8-0.60.3-0.2-1.6-1.6-1.4
Pavlov. Cond. response bias0.30.40.80.6-0.00.10.1-0.9-0.8-0.9
Time in closed arm before self-admin0.10.20.40.10.1-0.10.6-0.6-0.7-0.3
Time in closed arm after self-admin0.40.40.60.50.40.8-0.8-0.7-0.80.4
Time in open arm before self-admin0.20.31.3-0.6-1.10.00.1-0.4-0.4-0.1
Time in open arm after self-admin0.40.41.1-0.5-1.1-0.40.50.50.6-0.7
Bone: periosteal estimation3.17.519.04.44.22.8-2.4-1.0-0.80.3
Bone: periosteal perimeter1.12.17.32.71.91.4-0.8-0.5-0.4-0.9
Bone: post-yield work0.81.42.71.61.61.1-1.5-0.9-0.80.2
Progressive ratio test 1 active lever presses0.20.41.70.31.3-0.20.80.40.4-0.3
Progressive ratio test 1 breakpoint0.30.52.10.41.4-0.20.70.50.5-0.2
Progressive ratio test 1 inactive lever presses0.30.72.81.21.70.8-0.10.10.10.0
Progressive ratio test 2 active lever presses0.40.61.10.91.10.20.30.60.7-0.9
Progressive ratio test 2 breakpoint0.50.61.51.11.20.40.20.60.6-0.9
Progressive ratio test 2 inactive lever presses0.30.92.3-0.10.8-0.50.81.51.5-0.2
Incentive Sensitization - Responses0.10.40.80.90.40.7-0.30.40.4-0.8
Incentive Sensitization - Breakpoint0.20.41.11.00.40.8-0.50.30.3-0.8
Sum of active levers in priming session hrs 5-60.60.50.9-0.6-0.7-0.70.9-0.8-0.8-0.3
Progressive ratio0.10.20.80.3-0.30.2-0.40.10.2-0.9
Food seeking constrained by brief footshock4.86.09.02.73.02.9-3.0-1.8-1.71.7
Seeking ratio, punishment vs. effort0.81.73.91.42.01.3-1.1-0.9-0.91.1
Retroperitoneal fat weight0.41.96.7-0.42.0-0.1-1.00.90.82.6
Reaction time number correct0.31.01.8-1.0-0.9-1.31.40.80.8-0.8
Reaction time mean minus median0.00.20.6-0.5-0.1-0.1-0.7-0.2-0.20.8
Reaction time mean minus median AUC0.00.20.7-0.8-0.3-0.80.50.20.3-0.1
Reaction time num false alarms0.61.02.61.60.61.10.3-0.5-0.4-1.5
Reaction time num false alarms AUC0.40.92.81.71.01.00.1-0.3-0.2-1.2
Reaction time trials correct on left0.31.01.8-1.0-0.9-1.31.40.80.8-0.8
Reaction time trials on left0.31.01.7-1.0-0.8-1.31.30.80.9-0.8
Reaction time mean0.20.41.00.2-0.10.0-0.4-1.0-0.9-0.7
Reaction time mean AUC0.20.51.60.1-0.00.1-0.5-1.3-1.2-0.4
Median of all reaction times0.30.51.30.3-0.0-0.0-0.2-1.1-1.0-1.0
Reaction time omissions0.50.81.40.21.20.1-0.90.91.01.2
Reaction time false alarm rate1.21.64.22.01.01.7-0.8-1.0-0.9-0.7
Reaction time premature initiation rate0.20.30.70.10.3-0.40.60.90.90.1
Reaction time premature initiations0.30.81.8-0.4-0.1-0.91.11.31.3-0.1
Std. dev. reaction times0.20.51.60.50.50.7-1.3-0.6-0.50.6
Reaction time trials completed0.31.01.7-1.0-0.8-1.31.30.80.9-0.8
Reaction time trials AUC0.30.91.5-0.9-0.7-1.21.20.80.9-0.7
Run reversals in cocaine runway, females1.31.53.7-1.8-0.2-0.8-0.11.21.11.9
Run reversals in cocaine runway, males0.10.20.3-0.2-0.5-0.30.10.40.5-0.6
Latency to leave start box in cocaine runway0.20.20.7-0.3-0.80.10.3-0.4-0.6-0.5
Latency to leave start box in cocaine runway, F1.01.33.0-0.5-1.7-0.21.1-0.7-0.9-1.7
Latency to leave start box in cocaine runway, M0.60.61.70.20.60.7-1.1-0.3-0.41.3
Std. dev. time between licks in bursts0.20.51.2-1.1-0.1-0.9-0.10.40.40.9
Total sessions with >9 infusions1.51.85.1-1.5-0.5-1.62.31.00.9-0.9
Short access day 1 total inactive lever presses0.10.30.60.10.7-0.00.50.80.7-0.5
Short access day 10 total inactive lever presses0.00.30.9-0.20.0-0.2-0.30.70.60.9
Short access day 1 total infusions1.42.77.8-1.5-0.7-1.72.80.90.8-2.0
Short access day 10 total infusions0.30.62.10.21.4-0.10.50.90.80.2
Short access total infusions0.30.41.50.00.4-0.31.20.30.3-1.0
Short access day 1 locomotion2.03.46.6-1.80.3-2.22.62.12.0-0.5
Short access day 10 total locomotion0.41.67.31.12.70.8-0.60.20.21.2
Short access total locomotion0.60.91.4-0.71.2-0.91.21.11.10.3
One hour access (0.3 mA shock)0.30.30.80.90.80.6-0.1-0.3-0.3-0.4
Compulsive drug intake0.30.51.30.4-0.40.5-0.3-1.1-1.1-0.7
One hour access (shock baseline)0.10.31.00.41.00.10.00.80.70.2
Social response proportion0.10.10.2-0.0-0.4-0.30.4-0.1-0.1-0.3
Social responses0.20.30.80.40.40.20.2-0.9-0.90.1
Social time0.30.50.90.5-0.70.5-0.7-0.9-0.9-0.6
Soleus weight0.10.42.0-0.1-0.3-0.31.40.30.3-0.8
Bone: stiffness0.20.41.60.91.30.3-0.2-0.3-0.3-0.0
Tibialis anterior weight0.92.97.0-1.30.8-0.80.52.32.22.6
Time to tail flick, vehicle, before self-admin0.80.91.81.40.00.9-0.9-1.0-0.8-1.2
Time to tail flick, vehicle, after self-admin0.30.61.5-0.1-0.8-0.80.60.70.8-1.2
Time to tail flick, test, before self-admin0.91.01.31.11.10.9-1.1-0.9-0.90.8
Time to tail flick, test, after self-admin0.10.10.30.50.50.10.10.10.10.1
Delta time to tail flick, vehicle, before/after SA0.30.40.70.10.60.1-0.50.80.80.8
Delta time to tail flick, test, before/after SA0.10.21.00.4-0.3-0.10.30.10.2-1.0
Tibia length0.41.12.9-0.4-0.8-1.21.60.10.1-1.7
Ambulatory time before self-admin0.30.92.2-0.0-1.50.30.3-0.9-0.9-1.4
Ambulatory time after self-admin0.20.30.70.4-0.20.30.3-0.7-0.7-0.9
Bone: tissue strength0.91.01.7-0.7-1.3-1.11.3-0.3-0.3-1.3
Total heroin consumption1.82.15.31.1-1.20.90.1-1.8-1.8-2.3
Bone: trabecular number0.10.20.60.80.60.1-0.10.30.4-0.5
Bone: trabecular spacing0.20.30.60.00.10.3-0.5-0.8-0.80.5
Bone: trabecular thickness0.50.72.0-0.00.6-0.70.41.31.40.3
Bone: trabecular tissue density1.93.34.7-2.0-1.3-2.22.21.91.9-0.6
Water consumed over 24 hours0.10.20.9-0.50.20.10.20.20.10.9
Number of responses in last shaping day0.30.30.6-0.8-0.6-0.60.80.30.3-0.3