Hub : Genes

Pitpnc1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye isoform ratio XM_039087431.1 0.38 0.17 2.3e-03 0.14 0.15 0.18 0.16 3.8e-03 2.4e-03 1.1e-03 1.8e-03
2 IL gene expression Pitpnc1 0.3 0.14 6.2e-03 0.03 0.04 0.05 0.06 6.0e-02 4.3e-02 2.0e-02 1.3e-02
3 PL gene expression Pitpnc1 0.03 0.02 3.4e-03 0.01 0.01 0.03 0.02 1.9e-02 8.1e-03 7.0e-04 1.2e-03
4 Brain gene expression Pitpnc1 0.13 0.06 3.9e-07 0.07 0.08 0.09 0.08 7.0e-07 3.3e-08 9.2e-09 3.5e-08
5 LHb gene expression Pitpnc1 0.37 0.14 2.0e-03 0.13 0.11 0.19 0.14 6.4e-04 1.2e-03 3.0e-05 3.6e-04
6 Liver gene expression Pitpnc1 0.09 0.04 2.2e-08 0.04 0.06 0.05 0.05 2.0e-05 1.0e-06 6.3e-06 1.2e-06
7 RMTg intron excision ratio chr10_92173908_92184053 0.21 0.11 7.0e-03 0.07 0.01 0.09 0.11 7.1e-03 1.4e-01 2.5e-03 6.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.30.42.01.40.5-0.1-0.20.4-0.40.7
Area under the delay curve1.11.22.0-0.1-0.91.41.41.20.91.2
BMI with tail1.13.48.20.8-0.12.52.4-1.60.62.9
BMI without tail1.22.57.72.20.71.11.7-0.90.12.8
Body weight0.72.812.53.51.80.00.3-0.5-0.51.8
Weight adjusted by age0.70.81.7-1.2-1.30.10.80.61.10.6
Bone surface2.54.512.23.52.4-2.2-2.20.9-1.6-0.7
Bone volume1.62.710.43.21.7-1.3-1.30.9-1.00.1
Breakpoint value in progressive ratio session0.40.51.50.20.1-0.6-0.50.70.8-1.2
Number of licking bursts0.10.10.3-0.0-0.1-0.4-0.30.30.1-0.6
Context. condit. distance diff. score0.00.00.10.2-0.1-0.3-0.1-0.10.2-0.2
Locomotion velocity, session 10.10.10.50.70.4-0.2-0.00.50.10.1
Locomotion distance, session 10.50.61.20.8-0.10.50.91.10.70.9
Locomotion velocity, session 21.41.74.21.10.7-1.8-1.21.00.2-2.1
Locomotion distance, session 20.40.51.40.6-0.2-0.50.31.21.0-0.7
Locomotion velocity, session 31.61.95.4-0.1-1.60.71.51.62.3-0.0
Locomotion distance, session 30.80.93.10.6-0.7-0.20.31.81.3-0.7
Stereotopy head waving bouts, day 31.01.21.8-1.3-1.11.31.20.11.01.1
Stereotopy head waving duration, day 31.31.52.1-1.2-1.41.51.50.71.30.9
Locomotion velocity, session 70.10.20.6-0.30.2-0.2-0.4-0.8-0.3-0.2
Locomotion distance, session 70.00.00.10.30.3-0.1-0.10.0-0.2-0.2
Stereotopy head waving bouts, day 71.01.23.1-0.9-1.40.41.01.01.8-0.4
Stereotopy head waving duration, day 71.82.24.3-1.8-2.10.10.71.32.1-1.2
Locomotion velocity, session 80.81.02.00.91.0-1.4-1.3-0.1-0.6-0.9
Locomotion distance, session 80.20.30.80.90.1-0.9-0.30.50.3-0.6
Degree of sensitization distance0.70.81.9-0.01.2-0.0-0.5-1.2-1.40.5
Degree of sensitization stereotypy1.31.53.9-0.6-1.5-0.30.61.22.0-1.3
Conditioned locomotion0.10.10.30.20.5-0.3-0.3-0.5-0.50.3
Cocaine response after cond. corrected0.30.42.0-1.4-0.50.60.20.0-0.10.1
Cocaine response after cond. not corrected0.60.72.0-1.4-0.8-0.5-0.40.50.3-1.2
Cocaine response before conditioning1.11.32.50.5-1.0-1.3-0.11.51.2-1.6
Saline control response0.20.30.91.00.5-0.3-0.0-0.7-0.0-0.0
Bone: connectivity density0.50.92.61.61.1-0.8-0.80.5-0.80.2
Bone: cortical apparent density3.44.49.0-1.4-2.23.02.8-0.41.72.2
Bone: cortical area1.42.111.43.40.30.10.81.00.61.1
Bone: cortical porosity4.34.710.62.51.7-3.3-2.50.5-0.8-2.5
Bone: cortical porosity2.22.45.62.40.6-2.3-1.21.30.1-1.6
Bone: cortical thickness5.18.418.4-0.1-3.33.24.30.73.42.7
Bone: cortical thickness1.31.53.50.4-1.70.91.9-0.11.60.6
Bone: cortical tissue density3.14.18.5-1.5-2.12.92.6-0.51.52.1
Condit. Reinf. active minus inactive responses1.21.43.81.90.3-1.4-0.61.50.0-1.1
Condit. Reinf. active-inactive response ratio0.70.71.50.90.2-1.2-0.80.9-0.2-1.2
Condit. Reinf. active responses1.41.76.02.50.6-1.5-0.61.5-0.2-0.7
Condit. Reinf. inactive responses0.50.63.11.80.5-0.30.10.7-0.20.6
Incentive salience index mean1.21.53.82.00.4-1.6-0.91.10.0-1.3
Condit. Reinf. lever presses0.40.51.30.8-0.2-0.9-0.40.30.5-1.2
Condit. Reinf. active minus inactive responses2.83.510.53.20.5-2.0-0.72.70.4-1.4
Condit. Reinf. active-inactive response ratio1.31.42.51.40.5-1.6-1.11.3-0.4-1.5
Condit. Reinf. active responses2.83.914.93.91.1-2.2-0.92.2-0.1-0.9
Condit. Reinf. inactive responses1.51.910.03.20.8-0.90.21.10.20.4
Condit. Reinf. lever presses1.52.08.22.90.5-1.8-0.41.10.2-1.0
Condit. Reinf. lever reinforcers received2.33.212.53.51.1-1.9-0.81.9-0.2-0.7
Conditioned reinforcement - actives0.10.10.30.3-0.2-0.50.10.30.20.2
Conditioned reinforcement - inactives0.80.83.51.90.8-0.7-0.40.8-0.20.7
Conditioned locomotion0.70.93.21.81.1-0.8-0.4-0.3-0.90.5
Patch foraging indifference point 0 sec1.72.814.83.81.6-0.6-0.10.6-0.80.9
Patch foraging indifference point AUC0.40.52.41.60.8-0.1-0.10.2-0.30.6
Delay disc. indifference point, 0s delay0.60.71.6-1.3-1.00.80.80.50.60.6
Delay disc. indifference point, 16s delay1.41.43.1-0.0-0.91.81.60.70.81.5
Delay disc. indifference point, 2s delay0.40.41.20.6-0.10.40.51.1-0.01.0
Delay disc. indifference point, 24s delay1.41.33.71.50.11.21.30.30.41.9
Delay disc. indifference point, 4s delay0.80.91.6-0.9-1.30.70.91.21.0-0.1
Delay disc. indifference point, 8s delay1.81.83.6-0.7-1.21.91.70.91.21.5
Indifference point function ln k0.40.61.50.2-1.20.00.90.71.2-0.2
Indifference point function log k0.40.61.50.2-1.20.00.90.71.2-0.2
Patch foraging total patch changes 0 sec1.72.713.83.71.6-0.6-0.10.6-0.90.9
Patch foraging total patch changes 12 sec2.12.79.13.02.3-0.8-1.10.2-1.60.4
Patch foraging total patch changes 18 sec0.91.15.42.31.4-0.2-0.30.4-0.40.0
Patch foraging total patch changes 24 sec1.72.09.93.21.0-0.30.41.1-0.31.4
Patch foraging total patch changes 6 sec1.32.09.83.11.5-0.5-0.40.5-0.90.7
Patch foraging time to switch 0 sec0.30.52.3-1.50.20.2-0.5-0.8-0.4-0.7
Patch foraging water rate 0 sec0.91.46.42.51.2-0.7-0.1-0.1-0.71.1
Patch foraging water rate 12 sec0.50.82.00.0-1.01.01.40.41.00.7
Patch foraging water rate 18 sec0.30.40.70.8-0.7-0.20.70.60.80.4
Patch foraging water rate 24 sec0.20.30.9-0.2-0.40.00.40.90.9-0.3
Patch foraging water rate 6 sec0.30.51.00.2-0.70.61.00.30.90.8
Seeking ratio, delayed vs. immediate footshock0.20.20.60.3-0.10.50.6-0.10.20.8
Distance traveled before self-admin1.01.12.6-1.1-1.10.40.31.61.1-1.1
Distance traveled after self-admin0.91.13.3-0.2-0.8-0.5-0.31.41.0-1.8
Extensor digitorum longus weight1.76.712.3-3.1-0.33.31.5-3.5-1.23.1
Bone: elastic displacement1.11.23.2-0.7-1.80.51.30.71.50.1
Bone: elastic work0.30.31.21.1-0.20.00.5-0.30.20.8
Bone: endosteal estimation9.420.432.65.75.5-5.0-5.40.2-4.2-2.8
Bone: endosteal perimeter7.716.133.05.74.9-4.2-4.60.9-3.4-2.0
Epididymis fat weight1.22.76.10.41.80.8-0.2-2.4-1.62.5
Delta time in closed arm before/after self-admin0.30.30.70.20.4-0.8-0.70.3-0.2-0.7
Delta time in open arm before/after self-admin1.41.43.4-1.2-1.01.81.40.20.61.1
Diff in mean of infusions in LGA sessions0.50.61.2-1.1-0.80.70.8-0.50.90.1
Delay discount exponential model param0.70.71.2-0.20.6-1.1-1.0-1.0-0.6-1.1
Extinction: sum of active levers before priming0.20.20.50.30.00.70.5-0.30.00.5
Active lever presses in extinction session 60.60.62.11.50.9-0.3-0.5-0.2-0.7-0.4
Bone: final force0.81.38.02.80.6-0.5-0.10.7-0.10.4
Bone: final moment0.91.48.32.90.7-0.6-0.20.7-0.20.3
Food consumed during 24 hour testing period1.11.32.61.41.60.7-0.1-1.4-1.01.1
Glucose0.40.51.4-1.2-1.0-0.00.40.31.0-0.5
Heart weight0.60.91.70.2-1.30.11.21.31.10.4
Delay discount hyperbolic model param0.80.81.3-0.10.7-1.0-1.1-1.1-0.6-1.1
Intermittent access intake day 1-15 change1.91.93.3-0.11.7-0.6-1.7-1.8-1.8-0.8
Intermittent access intake escalation1.11.12.2-0.31.2-0.3-1.2-1.5-1.4-0.6
Intermittent access intake escalation 23.13.15.80.42.3-1.0-2.0-2.2-2.4-0.5
Intermitt. access day 1 inactive lever presses2.02.28.42.90.8-1.4-0.71.70.5-0.9
Intermitt. access day 15 inactive lever presses0.60.71.61.21.3-0.6-0.8-0.5-0.70.0
Intermitt. access escalation Index1.00.93.1-1.8-0.80.40.00.00.5-1.4
Intermittent access day 1 total infusions1.01.12.11.1-0.70.81.21.40.91.0
Intermittent access day 15 total infusions0.20.20.50.50.50.5-0.0-0.3-0.70.3
Intermittent access terminal intake (last 3 days)0.91.02.21.41.5-0.3-0.8-0.5-1.40.4
Intermittent access total infusions0.80.94.32.10.7-0.4-0.10.9-0.30.5
Intermittent access day 1 locomotion1.01.05.42.30.4-0.50.21.00.00.6
Intermittent access day 15 total locomotion2.02.17.92.81.9-1.0-1.0-0.3-1.20.1
Intermittent access total locomotion2.83.115.23.91.8-1.2-0.60.2-1.10.7
Intermittent access standard deviation0.50.51.91.40.9-0.1-0.3-0.3-0.60.5
Left kidney weight1.33.67.70.6-2.40.92.42.12.80.2
Right kidney weight0.71.93.40.8-1.71.01.81.51.7-0.1
Cocaine induced anxiety0.20.20.50.0-0.70.10.40.50.6-0.0
Post-drug Anxiety0.50.51.1-1.1-1.00.40.60.30.70.6
Baseline Anxiety0.80.92.3-1.5-0.80.80.9-0.60.51.0
Tail length0.72.05.52.31.8-1.5-1.10.1-1.20.6
Length with tail0.72.57.42.71.8-1.7-1.61.0-1.0-0.2
Length without tail0.30.51.50.50.9-0.8-1.20.1-0.6-0.6
Times rat made contact with spout0.30.40.80.60.9-0.2-0.6-0.4-0.8-0.2
Lifetime Intake1.11.26.12.50.4-0.40.31.20.10.7
Liver weight, left0.20.30.70.80.7-0.4-0.70.4-0.3-0.3
Liver weight, right0.71.23.1-0.3-0.71.61.40.50.61.7
Locomotor activity1.21.96.72.6-0.5-0.60.61.51.4-1.1
Locomotor testing distance1.21.97.12.7-0.4-0.60.71.61.4-1.0
Locomotor testing rearing1.21.94.91.91.0-1.5-1.1-0.0-0.0-2.2
Locomotion in novel chamber0.60.71.9-0.0-0.4-1.0-0.51.40.8-0.9
Locomotion in novel chamber post-restriction0.91.12.31.51.4-0.9-1.20.4-1.10.0
Fecal boli incidents, locomotor time 10.10.20.7-0.8-0.40.50.10.20.1-0.1
Change in fecal boli incidents, locomotor task0.60.62.00.1-0.21.00.9-0.3-0.21.4
Time >=10cm from walls, locomotor time 11.01.01.9-1.0-1.0-1.0-0.30.91.0-1.4
Bouts of movement, locomotor time 10.50.61.1-0.8-0.10.90.6-1.1-0.41.0
Total resting periods, locomotor time 10.70.81.4-0.90.01.20.5-1.1-0.61.2
Rest time, locomotor task time 10.30.31.7-1.3-0.20.5-0.0-0.5-0.30.2
Distance moved, locomotor task time 10.30.30.80.80.9-0.3-0.4-0.5-0.30.4
Vertical activity count, locomotor time 10.20.20.50.70.7-0.5-0.4-0.3-0.20.1
Time >=10cm from walls, locomotor time 21.31.42.4-0.80.8-1.6-1.6-1.2-0.5-1.4
Bouts of movement, locomotor time 20.60.61.5-0.8-0.20.90.6-1.2-0.01.0
Total resting periods, locomotor time 20.60.61.0-0.9-0.61.00.9-0.70.30.9
Rest time, locomotor task time 22.73.211.1-3.3-2.01.81.40.31.20.6
Distance moved, locomotor task time 21.41.73.21.01.8-1.1-1.4-1.6-1.0-0.7
Vertical activity count, locomotor time 22.52.75.02.22.2-1.4-1.6-1.5-1.4-0.7
Light reinforcement 11.22.24.70.8-1.01.82.2-0.01.22.0
Light reinforcement 21.31.74.40.4-0.91.41.70.71.12.1
Bone: marrow area9.320.331.25.65.5-5.0-5.40.2-4.2-2.9
Bone: maximum diameter2.13.916.24.01.7-1.5-1.31.7-0.7-0.4
Bone: maximum force1.32.312.63.50.9-0.20.41.1-0.11.1
Bone: maximum moment1.32.312.83.61.0-0.30.20.9-0.21.1
Mean time between licks in bursts0.20.31.0-0.00.50.60.2-0.6-0.51.0
Mean num. licks in bursts0.30.31.00.20.40.80.3-0.5-0.41.0
Cd content in liver0.80.94.5-2.1-0.7-0.1-0.3-0.9-0.3-0.3
Co content in liver0.60.71.6-0.9-0.2-1.0-1.0-0.3-0.2-1.3
Cu content in liver0.10.10.2-0.10.40.4-0.0-0.2-0.50.4
Fe content in liver0.30.40.80.5-0.50.00.40.90.7-0.8
K content in liver0.60.60.90.90.4-0.9-0.90.90.2-0.8
Mg content in liver0.30.31.0-0.10.5-0.5-1.0-0.4-0.7-0.2
Mn content in liver0.60.62.31.0-0.6-0.20.21.50.8-0.3
Na content in liver1.41.43.60.7-0.9-1.0-0.11.91.6-1.2
Rb content in liver0.60.71.4-0.6-1.2-0.60.01.10.8-1.0
Se content in liver2.12.64.3-1.3-2.01.31.71.92.10.2
Sr content in liver0.10.10.30.50.2-0.5-0.10.10.20.3
Zn content in liver1.31.54.0-0.4-1.21.11.02.01.50.5
Bone: minimum diameter5.19.529.65.43.8-2.8-2.80.4-2.6-0.3
Time in familiar zone, hab. session 11.11.02.40.71.4-0.5-1.1-0.8-1.6-0.1
Time in novel zone, hab. session 10.70.61.2-0.8-1.10.71.00.01.00.3
Total zone transitions, hab. session 10.20.31.81.30.2-0.10.40.20.40.4
Total locomotion distance, hab. session 10.50.73.81.90.60.30.60.40.30.7
Locomotion velocity, hab. session 10.50.73.51.90.70.10.40.50.20.6
Time in familiar zone, hab. session 21.61.73.21.41.3-1.8-1.7-0.0-1.0-1.1
Time in novel zone, hab. session 21.41.43.4-1.3-0.81.81.4-0.10.51.3
Total zone transitions, hab. session 20.10.10.30.60.3-0.10.1-0.30.4-0.1
Total locomotion distance, hab. session 20.50.71.41.10.80.80.5-0.6-0.21.2
Locomotion velocity, hab. session 20.50.71.70.90.71.00.6-0.5-0.11.3
Novel to familiar place preference ratio0.40.41.71.30.6-0.4-0.3-0.1-0.60.4
Novelty place preference0.20.31.11.10.4-0.4-0.3-0.2-0.40.2
Time in novel zone, NPP test0.20.21.11.10.3-0.6-0.3-0.0-0.3-0.1
Total zone transitions, NPP test0.91.32.70.9-0.80.91.61.21.50.9
Total locomotion distance, NPP test0.40.52.11.50.70.30.50.2-0.00.8
Locomotion velocity, NPP test0.81.22.61.10.21.41.40.40.51.6
Intraocular pressure0.91.32.8-0.1-0.51.71.50.81.01.4
Delta distance traveled before/after self-admin0.10.10.40.3-0.4-0.00.4-0.10.7-0.4
Delta ambulatory time before/after self-admin0.10.10.20.50.10.00.1-0.4-0.1-0.0
Parametrial fat weight0.81.64.00.01.60.5-0.9-1.6-2.01.1
Pavlov. Cond. lever latency0.91.24.1-2.0-0.01.30.2-1.0-0.81.0
Pavlov. Cond. magazine entry latency1.21.55.02.20.5-1.4-0.71.30.4-1.0
Pavlov. Cond. change in total contacts1.21.34.82.20.1-1.5-0.41.00.5-0.9
Pavlov. Cond. index score1.31.65.42.30.2-1.5-0.51.40.7-1.0
Pavlov. Cond. latency score1.21.54.82.20.1-1.4-0.41.30.9-1.0
Pavlov. Cond. lever contacts0.80.92.51.60.2-1.3-0.60.30.5-1.1
Pavlov. Cond. magazine entry number0.91.23.1-1.80.01.20.4-1.6-0.60.8
Pavlov. Cond. intertrial magazine entries0.91.14.02.00.10.00.91.20.21.2
Pavlov. Cond. lever-magazine prob. diff.1.21.54.82.20.0-1.3-0.31.40.9-0.9
Pavlov. Cond. response bias1.21.44.32.1-0.0-1.3-0.41.50.8-1.0
Pavlov. Cond. lever latency0.60.91.9-1.30.41.20.0-1.4-0.60.8
Pavlov. Cond. magazine entry latency1.11.32.5-1.6-1.5-0.50.21.01.3-1.2
Pavlov. Cond. change in total contacts0.81.22.61.1-0.2-1.6-0.61.50.5-1.3
Pavlov. Cond. index score0.81.02.00.4-0.7-1.3-0.21.40.8-1.4
Pavlov. Cond. latency score1.01.32.60.3-0.8-1.4-0.21.61.0-1.6
Pavlov. Cond. lever contacts0.40.51.31.2-0.2-0.90.10.90.4-0.4
Pavlov. Cond. magazine entry number1.51.83.31.71.80.3-0.5-1.3-1.61.3
Pavlov. Cond. intertrial magazine entries4.96.414.93.33.9-0.5-1.8-1.8-3.11.7
Pavlov. Cond. lever-magazine prob. diff.0.81.02.30.3-0.8-1.3-0.21.50.9-1.3
Pavlov. Cond. response bias0.30.41.00.7-0.3-0.90.01.00.4-0.6
Time in closed arm before self-admin0.30.40.9-0.0-0.90.00.60.40.9-0.7
Time in closed arm after self-admin0.70.72.3-0.20.3-1.2-1.0-0.0-0.2-1.5
Time in open arm before self-admin0.30.31.2-1.1-0.1-0.3-0.4-0.5-0.0-0.5
Time in open arm after self-admin0.50.61.7-0.8-0.41.30.70.00.31.1
Bone: periosteal estimation4.89.932.85.73.6-2.9-2.80.8-2.3-1.0
Bone: periosteal perimeter2.13.614.43.81.5-1.7-1.41.5-0.6-0.7
Bone: post-yield work1.62.25.52.41.7-1.6-1.60.3-1.1-0.6
Progressive ratio test 1 active lever presses1.21.26.02.40.4-0.80.11.30.10.3
Progressive ratio test 1 breakpoint1.31.36.82.60.4-0.70.21.30.20.5
Progressive ratio test 1 inactive lever presses1.82.09.13.00.4-0.70.22.00.60.1
Progressive ratio test 2 active lever presses1.01.14.32.10.7-0.7-0.41.4-0.10.5
Progressive ratio test 2 breakpoint1.21.34.62.21.1-1.1-0.81.1-0.50.3
Progressive ratio test 2 inactive lever presses1.41.66.92.60.7-0.30.11.5-0.21.2
Incentive Sensitization - Responses0.70.71.41.11.2-0.8-1.00.6-0.50.2
Incentive Sensitization - Breakpoint0.70.71.51.01.2-0.8-1.10.5-0.50.0
Sum of active levers in priming session hrs 5-60.30.30.9-0.4-1.00.10.40.10.6-0.7
Progressive ratio0.10.10.5-0.70.00.4-0.20.5-0.10.0
Food seeking constrained by brief footshock4.25.18.61.62.9-2.7-2.9-1.3-2.2-1.7
Seeking ratio, punishment vs. effort1.62.04.21.61.5-2.0-1.4-1.0-1.0-0.9
Retroperitoneal fat weight1.54.811.62.23.4-0.8-1.7-2.6-2.50.9
Reaction time number correct1.21.83.1-1.1-1.41.81.71.01.30.7
Reaction time mean minus median0.50.71.9-1.30.40.6-0.2-1.4-1.00.0
Reaction time mean minus median AUC0.40.51.2-1.0-0.61.10.7-0.3-0.10.2
Reaction time num false alarms1.52.07.92.80.3-0.60.12.10.7-0.7
Reaction time num false alarms AUC1.31.88.12.80.6-0.8-0.31.70.2-0.5
Reaction time trials correct on left1.21.83.1-1.1-1.41.81.71.01.30.7
Reaction time trials on left1.21.73.3-1.1-1.31.81.71.01.30.8
Reaction time mean0.30.40.9-1.0-0.3-0.7-0.50.1-0.2-0.9
Reaction time mean AUC0.40.51.4-1.1-0.3-0.8-0.6-0.2-0.3-1.2
Median of all reaction times0.40.51.4-0.6-0.4-1.2-0.60.50.0-1.1
Reaction time omissions0.40.61.3-0.30.81.00.0-0.6-1.10.8
Reaction time false alarm rate1.62.27.72.81.2-1.6-1.20.9-0.4-1.2
Reaction time premature initiation rate0.40.63.11.70.10.00.40.30.10.8
Reaction time premature initiations0.60.91.61.0-0.61.01.30.60.71.2
Std. dev. reaction times0.60.81.8-1.10.6-0.0-0.9-1.1-1.4-0.5
Reaction time trials completed1.21.73.3-1.1-1.31.81.71.01.30.8
Reaction time trials AUC1.01.52.8-1.0-1.21.71.50.81.10.8
Run reversals in cocaine runway, females1.51.45.1-1.40.50.6-0.0-2.3-1.01.2
Run reversals in cocaine runway, males0.20.20.5-0.3-0.60.40.40.70.40.3
Latency to leave start box in cocaine runway0.20.20.5-0.5-0.50.50.30.10.6-0.7
Latency to leave start box in cocaine runway, F1.41.63.7-0.3-1.50.71.01.61.9-0.9
Latency to leave start box in cocaine runway, M1.41.43.6-0.51.1-0.5-1.3-1.9-1.6-0.2
Std. dev. time between licks in bursts0.30.30.7-0.40.20.80.3-0.9-0.20.8
Total sessions with >9 infusions2.62.94.70.9-1.90.72.22.12.11.3
Short access day 1 total inactive lever presses0.70.82.61.6-0.0-0.50.21.50.90.3
Short access day 10 total inactive lever presses0.50.51.81.31.00.6-0.3-0.2-0.70.0
Short access day 1 total infusions3.03.25.91.8-1.60.62.02.42.31.0
Short access day 10 total infusions1.82.010.03.21.4-0.20.10.3-0.71.3
Short access total infusions1.61.88.22.9-0.1-0.50.71.70.90.4
Short access day 1 locomotion2.02.26.82.6-0.30.41.51.00.72.0
Short access day 10 total locomotion3.03.414.63.82.2-1.3-0.8-0.3-1.20.8
Short access total locomotion1.71.89.93.10.6-0.30.70.60.21.2
One hour access (0.3 mA shock)0.60.61.41.20.7-1.1-0.80.3-0.5-0.5
Compulsive drug intake0.50.51.7-0.8-0.70.2-0.00.50.4-1.3
One hour access (shock baseline)0.50.61.51.20.8-0.9-0.40.0-0.50.7
Social response proportion0.10.10.3-0.1-0.50.30.50.20.2-0.1
Social responses0.40.51.71.30.1-0.8-0.10.20.1-1.0
Social time0.20.30.8-0.8-0.0-0.3-0.60.1-0.2-0.9
Soleus weight0.51.43.10.8-1.30.41.11.81.70.1
Bone: stiffness0.91.47.52.70.8-0.9-0.31.0-0.10.0
Tibialis anterior weight0.62.15.70.10.81.60.4-2.4-1.22.1
Time to tail flick, vehicle, before self-admin0.40.50.9-0.5-0.0-0.9-1.00.7-0.2-0.8
Time to tail flick, vehicle, after self-admin0.20.30.80.1-0.10.30.30.8-0.30.9
Time to tail flick, test, before self-admin1.21.22.4-1.20.5-0.8-1.2-1.4-1.6-0.5
Time to tail flick, test, after self-admin0.30.31.1-0.1-0.61.00.80.3-0.10.4
Delta time to tail flick, vehicle, before/after SA0.80.81.81.01.20.2-0.2-0.6-1.31.0
Delta time to tail flick, test, before/after SA0.60.51.50.6-0.70.50.71.20.70.2
Tibia length0.82.35.70.7-1.60.61.72.42.00.5
Ambulatory time before self-admin0.70.82.0-0.8-0.80.00.01.41.1-1.0
Ambulatory time after self-admin0.50.61.70.3-0.6-0.20.01.30.9-1.0
Bone: tissue strength1.51.43.0-0.7-1.40.71.31.61.7-0.0
Total heroin consumption0.70.82.50.7-0.6-0.20.11.60.7-1.3
Bone: trabecular number0.50.83.31.80.6-0.5-0.31.2-0.00.3
Bone: trabecular spacing0.20.31.0-1.0-0.1-0.1-0.2-0.7-0.0-0.7
Bone: trabecular thickness0.60.82.71.70.70.10.10.1-0.61.3
Bone: trabecular tissue density1.82.65.4-0.5-1.32.32.30.71.21.9
Water consumed over 24 hours0.30.40.70.60.30.80.5-0.7-0.10.8
Number of responses in last shaping day0.40.41.01.0-0.40.20.60.90.8-0.0