Hub : Genes

Phykpl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Phykpl 0.23 0.23 1.1e-03 0.02 0.01 0.03 0.02 2.4e-03 9.8e-03 4.5e-04 1.3e-03
2 Liver intron excision ratio chr10_35846554_35847032 0.03 0.02 2.4e-03 0.01 0.02 0.02 0.02 1.2e-02 1.4e-03 2.6e-03 2.1e-03
3 Liver isoform ratio XM_039084983.1 0.04 0.03 2.1e-05 0.03 0.04 0.04 0.03 9.5e-05 6.2e-05 8.2e-06 9.8e-05
4 BLA mRNA stability Phykpl 0.06 0.04 2.4e-03 0.01 0.03 0.01 0.02 1.1e-01 9.3e-03 7.1e-02 3.6e-02
5 pVTA isoform ratio NM_001128196.2 0.23 0.33 2.9e-03 0.11 0.05 0.07 0.1 1.3e-05 3.1e-03 4.3e-04 4.4e-05
6 BLA gene expression Phykpl 0.06 0.04 3.1e-03 0 0.02 0 0.01 2.8e-01 2.9e-02 2.0e-01 1.3e-01
7 BLA alternative polyA XM_008767648.3 0.06 0.04 5.3e-03 0.04 0.03 0 0.03 4.4e-03 1.6e-02 3.3e-01 7.1e-03
8 BLA isoform ratio XM_008767648.3 0.06 0.04 5.9e-03 0.03 0.02 0.01 0.02 1.4e-02 2.7e-02 1.3e-01 2.1e-02
9 Adipose gene expression Phykpl 0.05 0.03 5.1e-06 0.05 0.05 0.05 0.05 3.8e-06 1.6e-06 1.1e-06 2.3e-06
10 Liver gene expression Phykpl 0.38 0.13 0.0e+00 0.37 0.39 0.38 0.39 3.9e-43 2.3e-45 8.3e-45 1.1e-45
11 Liver isoform ratio NM_001128196.2 0.06 0.03 1.0e-06 0.06 0.05 0.06 0.05 8.9e-07 5.7e-06 9.9e-07 3.5e-06
12 Brain gene expression Phykpl 0.03 0.02 1.1e-03 0.03 0.02 0.02 0.02 8.1e-04 7.5e-03 8.5e-03 5.9e-03
13 Brain mRNA stability Phykpl 0.09 0.05 1.8e-08 0.09 0.08 0.07 0.08 1.2e-08 7.5e-08 3.5e-07 5.0e-08
14 Liver intron excision ratio chr10_35856773_35858938 0.04 0.02 1.6e-04 0.04 0.03 0.03 0.03 8.1e-05 2.6e-04 1.2e-04 1.8e-04
15 pVTA mRNA stability Phykpl 0.13 0.08 6.6e-03 0.04 0.03 0.01 0.04 5.8e-03 1.5e-02 8.1e-02 1.1e-02
16 Brain isoform ratio XM_039084983.1 0.04 0.03 1.4e-04 0.05 0.04 0.05 0.05 2.2e-05 5.0e-05 3.1e-05 3.0e-05
17 Liver mRNA stability Phykpl 0.14 0.07 4.4e-16 0.12 0.13 0.13 0.14 1.5e-13 4.1e-14 3.9e-14 9.8e-15
18 Brain alternative polyA XM_039084983.1 0.05 0.03 9.6e-05 0.05 0.04 0.04 0.05 1.1e-05 1.1e-04 8.5e-05 3.4e-05
19 Adipose mRNA stability Phykpl 0.08 0.04 2.5e-09 0.08 0.08 0.08 0.07 4.5e-09 4.6e-09 4.2e-09 1.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.20.9-0.60.2-0.40.40.40.50.50.5-0.9-0.00.3-0.2-0.2-0.40.30.1-0.30.1-0.3
Area under the delay curve0.40.41.30.2-0.3-1.0-0.10.60.21.11.1-0.9-0.70.80.20.2-0.90.6-0.3-0.7-0.30.3
BMI with tail0.20.63.1-0.5-0.6-1.3-0.10.90.51.31.3-1.8-0.60.3-0.1-0.1-0.3-0.6-0.2-0.7-0.2-0.7
BMI without tail0.20.31.6-1.00.1-0.60.40.50.60.80.8-1.3-0.20.3-0.3-0.3-0.40.20.0-0.50.0-0.8
Body weight0.20.72.5-1.6-0.8-1.4-0.21.00.51.31.3-0.8-0.40.40.00.0-0.6-0.9-0.2-0.8-0.2-0.3
Weight adjusted by age0.80.92.7-1.6-1.6-1.0-1.40.2-1.10.50.50.2-0.70.60.80.8-0.5-1.5-0.9-0.7-0.90.1
Bone surface0.10.10.5-0.10.0-0.40.10.30.10.40.4-0.7-0.20.30.10.1-0.40.40.0-0.3-0.00.2
Bone volume0.10.21.0-0.70.4-0.30.50.30.70.40.4-1.00.10.2-0.3-0.3-0.30.30.4-0.10.4-0.2
Breakpoint value in progressive ratio session2.93.215.74.0-1.7-1.3-1.91.4-1.91.41.40.0-1.80.52.02.0-0.51.3-2.0-1.2-2.02.1
Number of licking bursts0.60.61.70.3-1.2-0.5-1.3-0.1-1.30.40.41.0-0.5-0.01.11.10.0-0.2-1.1-0.5-1.10.5
Context. condit. distance diff. score0.30.41.01.0-0.9-0.6-0.8-0.0-0.60.60.60.3-0.7-0.10.70.70.1-0.2-0.7-0.4-0.70.2
Locomotion velocity, session 10.10.10.2-0.10.20.40.2-0.40.2-0.4-0.40.20.4-0.5-0.3-0.30.4-0.30.30.40.3-0.5
Locomotion distance, session 10.81.04.8-0.4-0.30.8-0.3-1.4-0.2-1.0-1.02.20.8-1.4-0.3-0.31.5-1.80.20.90.2-0.6
Locomotion velocity, session 20.40.52.50.4-0.10.6-0.0-0.70.1-0.9-0.91.20.6-0.8-0.4-0.40.8-1.60.40.80.4-0.5
Locomotion distance, session 20.60.85.0-0.9-0.60.4-0.4-1.0-0.1-0.7-0.71.60.6-1.0-0.4-0.41.0-2.20.20.70.2-0.8
Locomotion velocity, session 31.82.15.61.9-2.4-1.5-2.20.7-1.81.11.10.5-1.70.91.61.6-0.7-0.9-1.7-1.2-1.71.0
Locomotion distance, session 30.60.72.20.7-1.5-1.0-1.20.4-0.90.80.80.4-0.80.40.80.8-0.4-0.9-0.9-0.7-0.90.3
Stereotopy head waving bouts, day 30.10.20.7-0.30.40.60.2-0.30.1-0.6-0.60.80.4-0.2-0.2-0.20.1-0.20.40.50.40.2
Stereotopy head waving duration, day 30.10.10.50.7-0.10.2-0.3-0.1-0.5-0.3-0.30.7-0.10.10.30.3-0.10.2-0.20.1-0.20.6
Locomotion velocity, session 70.40.41.9-0.00.40.50.5-0.90.6-0.4-0.41.40.6-0.8-0.5-0.50.8-0.50.60.80.6-0.2
Locomotion distance, session 70.20.21.90.10.20.40.1-0.90.1-0.1-0.11.40.4-0.8-0.1-0.10.80.00.10.40.10.0
Stereotopy head waving bouts, day 71.51.72.3-0.51.21.51.2-1.21.2-1.5-1.51.11.3-1.2-1.5-1.51.2-1.41.41.51.4-0.8
Stereotopy head waving duration, day 70.40.50.70.10.60.90.6-0.80.6-0.8-0.80.70.6-0.8-0.8-0.80.8-0.70.70.80.7-0.3
Locomotion velocity, session 81.21.44.81.8-2.2-0.9-1.90.2-1.40.50.51.2-1.00.11.11.10.0-1.9-1.1-0.5-1.10.4
Locomotion distance, session 80.50.72.70.5-1.6-0.8-1.3-0.1-0.90.60.60.9-0.6-0.20.70.70.2-1.4-0.9-0.5-0.9-0.0
Degree of sensitization distance1.21.22.1-0.71.41.41.2-1.40.9-1.1-1.11.11.3-1.3-0.9-0.91.20.31.01.21.0-0.3
Degree of sensitization stereotypy1.71.93.0-0.91.31.51.4-1.11.5-1.4-1.40.71.4-1.2-1.7-1.71.2-1.41.61.41.6-1.1
Conditioned locomotion0.20.30.5-0.70.70.50.7-0.40.7-0.3-0.30.10.6-0.6-0.6-0.60.5-0.10.60.50.6-0.5
Cocaine response after cond. corrected0.91.02.1-1.01.30.91.4-0.51.5-0.7-0.70.01.1-0.8-1.3-1.30.7-0.31.30.91.2-0.6
Cocaine response after cond. not corrected1.21.32.4-1.11.51.11.5-0.81.5-0.8-0.8-0.11.3-1.1-1.4-1.41.0-0.21.41.11.4-0.9
Cocaine response before conditioning0.00.00.4-0.2-0.0-0.10.1-0.10.20.10.1-0.50.1-0.1-0.1-0.10.1-0.00.10.00.2-0.6
Saline control response0.00.00.1-0.3-0.1-0.2-0.00.30.00.20.20.30.00.10.10.1-0.20.4-0.0-0.1-0.10.1
Bone: connectivity density0.00.00.20.4-0.2-0.1-0.2-0.2-0.30.10.1-0.1-0.2-0.10.20.20.10.1-0.3-0.1-0.30.2
Bone: cortical apparent density0.20.32.51.6-0.3-0.0-0.50.3-0.7-0.0-0.00.1-0.30.30.60.6-0.20.4-0.5-0.2-0.50.5
Bone: cortical area0.40.62.1-1.40.2-0.80.71.11.11.01.0-1.20.00.7-0.4-0.4-0.90.30.5-0.50.5-0.3
Bone: cortical porosity1.21.34.1-1.51.1-0.01.60.72.00.10.1-1.60.90.3-1.5-1.5-0.4-0.61.50.31.5-1.3
Bone: cortical porosity1.71.85.4-1.91.3-0.01.80.72.30.10.1-1.81.10.3-1.8-1.8-0.5-0.71.70.41.7-1.4
Bone: cortical thickness0.81.33.4-1.1-0.9-1.6-0.51.80.11.61.6-1.8-0.91.50.40.4-1.60.1-0.5-1.3-0.50.2
Bone: cortical thickness1.82.14.7-0.5-1.0-2.1-0.62.0-0.12.22.2-2.1-1.41.70.80.8-1.90.9-0.8-1.8-0.80.6
Bone: cortical tissue density0.20.32.61.6-0.30.0-0.50.2-0.7-0.1-0.10.2-0.30.30.60.6-0.20.4-0.5-0.1-0.50.5
Condit. Reinf. active minus inactive responses3.43.96.4-0.91.92.31.8-2.51.7-2.0-2.01.82.2-2.5-2.0-2.02.5-1.21.82.21.8-1.4
Condit. Reinf. active-inactive response ratio1.21.33.3-0.10.81.40.7-1.80.6-1.2-1.21.31.1-1.7-0.9-0.91.7-0.80.71.30.7-0.6
Condit. Reinf. active responses2.32.84.4-0.82.12.01.9-1.81.7-1.6-1.61.21.9-1.9-1.9-1.91.8-0.31.61.91.6-1.0
Condit. Reinf. inactive responses0.30.42.2-0.00.9-0.10.80.70.70.40.4-0.70.00.6-0.3-0.3-0.71.50.3-0.20.30.2
Incentive salience index mean1.72.04.0-1.21.21.61.2-2.01.2-1.3-1.31.41.6-2.0-1.4-1.41.9-1.01.21.61.2-1.1
Condit. Reinf. lever presses0.10.21.1-1.10.20.30.2-0.60.2-0.2-0.20.20.5-0.6-0.2-0.20.5-0.30.20.30.2-0.5
Condit. Reinf. active minus inactive responses2.32.95.4-2.02.31.92.2-1.51.9-1.4-1.40.52.0-1.5-1.9-1.91.40.31.91.61.9-1.2
Condit. Reinf. active-inactive response ratio0.70.82.3-1.11.50.91.3-0.81.1-0.4-0.40.01.0-0.6-0.9-0.90.51.10.80.70.8-0.5
Condit. Reinf. active responses1.31.83.7-1.11.91.61.7-1.21.4-1.2-1.20.51.6-1.3-1.4-1.41.20.61.51.31.4-0.7
Condit. Reinf. inactive responses0.10.10.70.80.30.30.1-0.00.0-0.2-0.20.20.1-0.2-0.0-0.00.20.50.10.10.10.5
Condit. Reinf. lever presses0.60.81.8-0.11.31.21.0-1.10.6-0.8-0.81.11.0-1.0-0.6-0.61.01.00.70.90.70.0
Condit. Reinf. lever reinforcers received1.52.14.2-0.92.11.81.8-1.51.5-1.4-1.40.81.7-1.6-1.5-1.51.50.61.51.51.5-0.7
Conditioned reinforcement - actives0.30.31.5-0.6-0.60.2-0.8-0.2-0.9-0.2-0.21.0-0.40.10.60.6-0.0-0.2-0.6-0.3-0.61.2
Conditioned reinforcement - inactives0.20.21.4-0.70.2-0.30.30.50.40.50.5-1.2-0.20.6-0.1-0.1-0.60.50.0-0.40.1-0.3
Conditioned locomotion0.40.51.2-1.10.80.90.8-0.80.7-0.5-0.50.60.6-0.5-0.7-0.70.50.10.70.40.60.6
Patch foraging indifference point 0 sec0.81.44.81.2-0.2-0.9-0.51.5-0.81.01.0-1.7-1.01.30.90.9-1.32.2-0.9-1.2-1.01.2
Patch foraging indifference point AUC4.45.16.6-2.02.62.42.5-2.52.4-2.0-2.01.42.4-2.5-2.6-2.62.4-0.92.42.32.4-1.8
Delay disc. indifference point, 0s delay0.91.01.71.0-1.1-1.3-0.90.9-0.61.31.3-1.2-1.10.81.01.0-0.90.2-1.0-1.1-0.90.7
Delay disc. indifference point, 16s delay1.41.53.10.7-1.0-1.7-0.81.2-0.51.71.7-1.3-1.41.31.01.0-1.31.0-1.0-1.3-1.10.8
Delay disc. indifference point, 2s delay0.20.20.7-0.1-0.2-0.60.10.70.40.60.6-0.9-0.20.5-0.1-0.1-0.7-0.20.1-0.30.20.1
Delay disc. indifference point, 24s delay0.80.82.1-0.0-0.9-1.4-0.61.1-0.31.41.4-0.7-1.00.90.60.6-0.60.5-0.8-1.1-0.80.5
Delay disc. indifference point, 4s delay0.50.51.60.21.20.11.20.21.20.20.2-1.10.30.2-0.7-0.7-0.31.20.70.30.8-0.4
Delay disc. indifference point, 8s delay0.40.40.80.2-0.4-0.9-0.40.5-0.30.90.9-0.7-0.80.90.50.5-0.80.7-0.6-0.7-0.60.3
Indifference point function ln k0.70.92.00.6-0.8-1.2-0.71.3-0.61.11.1-1.4-0.90.91.11.1-0.90.7-0.8-1.0-0.80.5
Indifference point function log k0.70.92.00.6-0.8-1.2-0.71.3-0.61.11.1-1.4-0.90.91.11.1-0.90.7-0.8-1.0-0.80.5
Patch foraging total patch changes 0 sec0.60.94.81.20.2-0.6-0.11.2-0.40.80.8-1.6-0.71.10.60.6-1.02.2-0.5-0.9-0.61.0
Patch foraging total patch changes 12 sec0.60.81.70.91.21.30.8-1.20.3-1.0-1.01.00.8-1.0-0.6-0.61.11.00.50.90.4-0.0
Patch foraging total patch changes 18 sec0.10.10.3-0.30.3-0.10.40.40.40.20.2-0.2-0.00.5-0.4-0.4-0.50.30.3-0.20.20.3
Patch foraging total patch changes 24 sec0.80.92.3-0.71.51.11.3-0.81.0-0.9-0.90.31.0-0.7-1.3-1.30.60.61.00.81.1-0.2
Patch foraging total patch changes 6 sec0.30.41.00.41.01.00.7-0.70.4-0.7-0.70.50.6-0.9-0.4-0.40.90.80.50.60.40.1
Patch foraging time to switch 0 sec0.30.51.51.0-1.0-0.1-1.1-0.0-1.2-0.2-0.21.0-0.40.30.80.8-0.2-0.5-0.9-0.2-0.80.5
Patch foraging water rate 0 sec0.10.20.60.60.70.30.6-0.20.5-0.0-0.0-0.40.2-0.7-0.3-0.30.60.80.40.30.40.2
Patch foraging water rate 12 sec0.20.31.00.2-0.5-0.8-0.30.5-0.01.01.0-0.0-0.6-0.00.40.4-0.10.4-0.4-0.6-0.30.8
Patch foraging water rate 18 sec0.70.94.51.30.0-0.9-0.11.0-0.21.31.3-0.9-0.90.70.50.5-0.82.1-0.6-0.9-0.61.2
Patch foraging water rate 24 sec0.30.52.91.40.1-0.3-0.20.1-0.40.70.7-0.5-0.5-0.20.60.60.21.7-0.6-0.3-0.70.5
Patch foraging water rate 6 sec0.10.10.60.8-0.3-0.4-0.20.1-0.10.50.5-0.7-0.4-0.30.20.20.30.1-0.3-0.2-0.20.2
Seeking ratio, delayed vs. immediate footshock0.40.41.2-0.6-1.1-0.9-0.90.6-0.60.60.6-0.5-0.50.20.70.7-0.4-0.8-0.7-0.5-0.70.3
Distance traveled before self-admin0.60.61.7-0.7-0.2-0.9-0.11.0-0.11.11.1-1.3-0.61.10.40.4-1.21.2-0.3-0.8-0.50.5
Distance traveled after self-admin0.40.41.5-1.21.00.41.0-0.20.90.00.0-0.60.5-0.0-0.7-0.70.30.90.70.30.6-0.8
Extensor digitorum longus weight0.51.83.7-1.20.91.50.9-1.70.8-1.3-1.31.41.4-1.9-1.1-1.11.9-1.31.11.51.1-1.2
Bone: elastic displacement0.10.10.8-0.30.1-0.20.20.60.30.10.1-0.9-0.00.5-0.2-0.2-0.5-0.20.3-0.10.3-0.5
Bone: elastic work3.95.09.10.4-2.0-2.9-1.72.9-1.32.82.8-3.0-2.42.71.91.9-2.71.4-2.0-2.7-2.00.8
Bone: endosteal estimation0.71.63.5-0.81.91.21.9-0.91.8-0.9-0.90.71.5-1.1-1.4-1.40.90.31.61.31.6-0.8
Bone: endosteal perimeter2.04.17.2-1.12.72.22.6-1.82.5-1.7-1.71.32.4-2.0-2.3-2.31.8-0.12.42.22.4-1.4
Epididymis fat weight0.20.41.1-0.2-0.8-1.0-0.50.8-0.20.90.9-0.2-0.60.50.30.3-0.6-0.2-0.5-0.6-0.50.5
Delta time in closed arm before/after self-admin1.21.23.61.01.11.50.8-1.10.4-1.4-1.41.20.9-1.6-0.7-0.71.90.20.71.10.70.1
Delta time in open arm before/after self-admin0.30.31.4-1.20.1-0.20.3-0.10.5-0.0-0.0-0.20.30.7-0.4-0.4-1.1-0.70.40.00.4-1.1
Diff in mean of infusions in LGA sessions9.910.938.36.2-3.0-3.0-3.42.7-3.52.92.9-1.7-3.62.43.83.8-2.03.3-3.7-2.9-3.71.5
Delay discount exponential model param0.30.30.90.20.10.9-0.1-0.6-0.4-0.9-0.90.90.5-0.80.00.00.8-0.40.10.50.0-0.0
Extinction: sum of active levers before priming4.04.013.63.7-1.9-2.3-1.72.4-1.42.42.4-1.6-2.21.11.81.8-1.31.1-1.9-1.8-2.01.7
Active lever presses in extinction session 60.30.34.12.0-0.20.2-0.3-0.1-0.5-0.2-0.20.2-0.2-0.20.20.20.20.1-0.30.1-0.4-0.3
Bone: final force0.61.04.1-2.00.80.31.2-0.11.5-0.1-0.1-0.61.0-0.4-1.2-1.20.3-0.81.20.51.2-1.1
Bone: final moment0.40.63.7-1.90.4-0.00.80.31.20.10.1-0.80.6-0.1-0.9-0.9-0.1-0.80.90.20.9-0.9
Food consumed during 24 hour testing period0.20.30.9-0.7-1.0-0.4-0.9-0.1-0.70.40.40.4-0.4-0.20.40.40.2-0.6-0.7-0.4-0.70.1
Glucose0.81.21.9-0.4-0.9-1.3-0.81.3-0.71.41.4-1.3-1.21.30.90.9-1.31.2-1.0-1.3-1.10.7
Heart weight1.52.24.4-0.0-2.1-2.1-1.71.4-1.31.71.7-1.3-1.71.41.41.4-1.4-0.5-1.5-1.7-1.51.0
Delay discount hyperbolic model param0.40.41.2-0.10.31.00.0-0.8-0.3-1.1-1.11.10.6-0.9-0.2-0.21.0-0.50.30.70.2-0.2
Intermittent access intake day 1-15 change1.41.48.0-2.81.30.71.4-0.21.3-0.6-0.6-0.51.00.2-1.3-1.3-0.10.31.20.51.3-1.7
Intermittent access intake escalation1.31.37.1-2.71.30.71.4-0.21.3-0.6-0.6-0.41.00.2-1.2-1.2-0.10.31.10.51.2-1.8
Intermittent access intake escalation 21.01.07.1-2.71.00.51.1-0.21.0-0.6-0.60.10.70.2-1.0-1.0-0.00.01.00.31.0-1.4
Intermitt. access day 1 inactive lever presses0.60.71.31.1-1.1-1.1-0.80.5-0.31.11.1-0.9-0.90.40.70.7-0.6-0.7-0.7-0.7-0.70.6
Intermitt. access day 15 inactive lever presses0.50.61.5-0.6-0.5-0.9-0.31.0-0.11.21.2-1.2-0.70.60.50.5-0.40.7-0.4-0.9-0.5-0.2
Intermitt. access escalation Index0.80.72.2-1.40.50.50.8-0.31.0-0.6-0.60.20.9-0.7-1.0-1.00.3-1.50.90.71.0-0.9
Intermittent access day 1 total infusions0.20.20.60.6-0.8-0.2-0.70.1-0.50.50.5-0.2-0.5-0.00.50.50.2-0.5-0.6-0.5-0.50.6
Intermittent access day 15 total infusions0.40.45.3-2.30.30.20.50.00.70.00.0-0.60.30.2-0.5-0.5-0.1-0.30.4-0.20.5-0.7
Intermittent access terminal intake (last 3 days)0.70.83.8-2.00.80.41.1-0.21.4-0.1-0.1-0.70.7-0.3-1.0-1.00.5-0.71.00.31.0-1.0
Intermittent access total infusions0.20.21.2-1.10.10.10.4-0.10.70.20.2-0.40.2-0.2-0.4-0.40.4-0.60.4-0.10.4-0.2
Intermittent access day 1 locomotion0.20.21.11.1-0.40.2-0.4-0.7-0.3-0.1-0.10.6-0.0-0.70.20.20.7-0.6-0.30.2-0.20.6
Intermittent access day 15 total locomotion1.82.03.0-1.71.61.51.6-1.51.5-1.4-1.40.81.5-0.9-1.6-1.61.2-0.61.51.31.6-1.3
Intermittent access total locomotion1.01.22.2-0.21.01.31.0-1.51.0-1.1-1.10.71.2-1.3-1.1-1.11.4-0.71.01.21.1-0.7
Intermittent access standard deviation1.71.84.5-1.7-0.8-2.0-0.31.90.11.71.7-1.7-1.12.10.50.5-2.10.5-0.5-1.7-0.50.3
Left kidney weight1.74.811.2-0.8-3.3-3.0-2.82.2-2.02.32.3-0.7-2.22.12.12.1-2.2-1.2-2.1-2.5-2.11.8
Right kidney weight0.41.13.8-0.3-1.9-1.5-1.41.0-0.80.90.9-0.7-0.90.50.80.8-0.5-1.9-0.9-0.9-0.80.2
Cocaine induced anxiety0.30.41.20.10.1-0.90.40.80.71.11.1-0.5-0.20.4-0.1-0.1-0.80.80.1-0.50.10.8
Post-drug Anxiety1.41.65.10.9-0.3-1.6-0.31.5-0.21.81.8-0.9-1.21.30.80.8-1.42.3-0.8-1.4-0.81.5
Baseline Anxiety1.31.43.10.71.41.80.9-1.60.4-1.6-1.60.51.0-1.3-0.8-0.81.60.70.81.20.8-1.2
Tail length0.10.22.8-1.7-0.4-0.3-0.30.4-0.10.20.20.3-0.10.60.10.1-0.6-0.5-0.1-0.4-0.1-0.0
Length with tail0.20.61.9-1.4-1.0-0.9-0.70.8-0.40.70.70.7-0.40.80.60.6-0.9-0.4-0.5-0.7-0.50.7
Length without tail0.30.61.6-0.3-1.3-1.1-1.00.6-0.50.90.90.5-0.50.40.80.8-0.5-0.6-0.7-0.6-0.61.1
Times rat made contact with spout0.50.62.3-0.1-1.0-0.1-1.1-0.8-1.1-0.0-0.01.5-0.1-0.80.80.80.9-0.5-0.9-0.0-0.90.2
Lifetime Intake0.10.11.0-0.6-0.2-0.00.1-0.00.50.30.3-0.40.1-0.3-0.3-0.30.4-1.00.2-0.10.3-0.1
Liver weight, left1.52.44.4-0.4-2.0-2.1-1.72.0-1.41.51.5-1.6-1.62.11.31.3-2.1-0.1-1.5-1.8-1.50.5
Liver weight, right0.40.72.4-0.8-0.6-1.3-0.11.20.41.11.1-1.5-0.71.1-0.1-0.1-1.1-0.4-0.1-0.7-0.1-0.6
Locomotor activity0.30.51.9-0.30.9-0.11.2-0.31.40.30.3-0.10.5-0.6-0.9-0.90.50.30.90.50.9-0.2
Locomotor testing distance0.30.51.10.51.10.51.0-0.80.9-0.2-0.20.10.6-0.9-0.5-0.50.90.80.70.70.7-0.2
Locomotor testing rearing0.30.41.31.11.10.31.0-0.40.9-0.1-0.1-0.30.4-0.6-0.4-0.40.61.00.60.60.7-0.3
Locomotion in novel chamber0.40.51.2-1.00.60.90.3-1.1-0.0-1.0-1.00.50.7-0.8-0.6-0.60.70.20.20.60.2-0.6
Locomotion in novel chamber post-restriction1.51.93.8-1.41.51.71.3-1.40.9-1.9-1.91.21.6-0.9-1.3-1.30.8-0.81.51.51.5-0.7
Fecal boli incidents, locomotor time 10.60.73.1-1.80.90.41.1-0.31.2-0.3-0.30.30.7-0.2-1.1-1.10.0-0.41.00.50.9-0.3
Change in fecal boli incidents, locomotor task0.30.32.20.30.1-0.40.10.80.10.40.4-1.5-0.20.60.30.3-0.50.6-0.0-0.3-0.1-0.7
Time >=10cm from walls, locomotor time 10.70.72.2-0.31.50.41.5-0.51.40.10.1-0.40.7-0.6-1.0-1.00.41.11.00.50.80.2
Bouts of movement, locomotor time 10.70.85.7-2.40.4-0.60.51.10.50.70.7-1.2-0.21.3-0.1-0.1-1.21.00.2-0.80.1-0.5
Total resting periods, locomotor time 11.31.54.8-2.2-0.2-1.3-0.01.70.01.41.4-1.5-0.81.90.50.5-1.91.4-0.4-1.4-0.50.1
Rest time, locomotor task time 11.01.12.5-0.7-0.9-1.5-0.71.6-0.51.21.2-1.3-0.91.50.90.9-1.50.3-0.6-1.2-0.60.0
Distance moved, locomotor task time 10.40.41.40.8-0.4-0.4-0.60.0-0.80.30.30.2-0.50.30.70.7-0.31.0-0.8-0.4-0.71.2
Vertical activity count, locomotor time 10.20.21.21.10.20.4-0.0-0.5-0.2-0.4-0.40.30.2-0.60.20.20.60.3-0.10.4-0.10.2
Time >=10cm from walls, locomotor time 20.70.72.91.71.20.41.3-0.41.3-0.0-0.0-1.00.5-0.8-0.7-0.70.70.61.00.61.00.1
Bouts of movement, locomotor time 21.11.23.31.1-0.5-1.0-0.61.3-0.81.11.1-0.9-1.21.31.21.2-0.91.8-1.0-1.2-1.01.0
Total resting periods, locomotor time 21.31.43.50.7-0.6-1.1-0.71.5-0.91.21.2-1.0-1.31.51.31.3-1.11.9-1.0-1.3-1.11.1
Rest time, locomotor task time 20.40.41.8-1.30.0-0.70.21.30.40.70.7-1.1-0.20.9-0.1-0.1-0.90.40.1-0.60.1-0.3
Distance moved, locomotor task time 20.40.41.51.2-0.40.4-0.7-1.0-1.0-0.6-0.60.9-0.1-0.50.60.60.6-0.1-0.50.3-0.40.7
Vertical activity count, locomotor time 20.70.81.91.4-0.10.9-0.3-1.2-0.4-1.2-1.21.20.5-1.20.10.11.4-1.30.20.90.20.2
Light reinforcement 10.10.10.30.30.10.5-0.0-0.2-0.1-0.5-0.50.40.3-0.50.00.00.6-0.20.20.30.10.3
Light reinforcement 20.30.42.20.4-0.1-0.6-0.20.7-0.30.70.7-1.5-0.40.60.50.5-0.61.0-0.5-0.6-0.50.2
Bone: marrow area0.71.63.3-0.71.81.21.8-1.01.7-0.9-0.90.81.5-1.1-1.4-1.41.00.31.51.31.5-0.8
Bone: maximum diameter0.61.13.2-1.11.40.71.6-0.41.8-0.4-0.40.31.2-0.7-1.4-1.40.60.01.50.91.4-0.8
Bone: maximum force0.20.41.6-1.3-0.1-0.80.30.90.70.80.8-1.1-0.10.6-0.2-0.2-0.7-0.10.3-0.50.3-0.3
Bone: maximum moment0.30.61.7-1.2-0.4-1.1-0.11.20.31.01.0-1.3-0.41.00.10.1-1.1-0.1-0.1-0.8-0.1-0.1
Mean time between licks in bursts0.50.83.01.7-0.70.5-0.9-0.8-1.1-0.8-0.81.7-0.1-0.70.70.70.8-0.6-0.50.5-0.50.6
Mean num. licks in bursts0.10.10.3-0.30.50.20.5-0.10.4-0.1-0.1-0.40.2-0.2-0.4-0.40.20.30.30.20.3-0.3
Cd content in liver0.60.62.00.60.91.40.4-0.8-0.2-1.4-1.41.00.7-0.5-0.4-0.40.70.40.30.90.40.2
Co content in liver0.30.30.80.2-0.4-0.8-0.30.7-0.20.80.8-0.5-0.60.80.40.4-0.90.4-0.4-0.6-0.50.2
Cu content in liver0.91.13.01.11.71.21.5-0.81.2-0.6-0.60.31.0-1.0-1.0-1.01.01.21.01.01.0-0.7
Fe content in liver0.30.40.8-0.4-0.8-0.8-0.60.9-0.30.50.5-0.6-0.60.90.40.4-0.9-0.7-0.4-0.6-0.40.2
K content in liver0.90.92.60.40.20.90.3-1.00.5-1.0-1.01.50.9-1.2-0.7-0.71.2-1.60.71.10.8-0.8
Mg content in liver1.61.64.90.50.51.50.4-1.70.3-1.5-1.52.21.2-1.8-0.7-0.71.9-1.40.81.50.8-0.6
Mn content in liver1.72.03.6-1.01.91.41.9-1.01.9-0.9-0.90.51.7-1.3-1.7-1.71.2-0.01.71.41.6-1.5
Na content in liver0.90.91.80.7-1.3-1.1-1.20.8-1.10.90.90.8-1.00.81.01.0-0.80.0-1.0-0.9-1.11.0
Rb content in liver0.60.71.91.40.41.20.2-0.9-0.0-1.3-1.31.40.5-0.8-0.4-0.40.9-0.70.51.00.5-0.1
Se content in liver0.40.51.20.6-1.1-0.8-0.90.8-0.70.50.5-0.3-0.70.80.70.7-0.8-0.5-0.7-0.6-0.70.2
Sr content in liver0.50.51.30.8-0.5-0.2-0.80.0-1.10.10.10.5-0.60.30.90.9-0.30.7-0.9-0.5-0.91.1
Zn content in liver1.21.34.40.80.51.30.3-1.50.2-1.3-1.32.11.0-1.7-0.6-0.61.7-1.10.61.30.7-0.3
Bone: minimum diameter0.10.20.8-0.50.50.00.70.10.90.20.20.20.5-0.1-0.5-0.50.00.10.60.20.6-0.2
Time in familiar zone, hab. session 10.30.31.4-0.50.4-0.50.60.70.80.50.5-1.2-0.20.7-0.4-0.4-0.80.50.4-0.30.4-0.0
Time in novel zone, hab. session 10.30.31.2-0.0-0.00.30.2-0.70.4-0.3-0.31.10.6-0.8-0.4-0.40.8-1.10.40.60.4-0.5
Total zone transitions, hab. session 13.04.211.3-0.70.32.20.3-2.80.3-2.4-2.43.42.0-2.8-1.2-1.22.8-3.21.22.31.2-1.4
Total locomotion distance, hab. session 10.50.72.9-0.60.10.60.3-0.90.5-0.8-0.81.30.9-0.9-0.8-0.80.9-1.70.70.90.7-0.7
Locomotion velocity, hab. session 10.20.32.1-0.3-0.60.2-0.4-0.7-0.2-0.4-0.41.10.3-0.5-0.1-0.10.5-1.40.00.40.0-0.4
Time in familiar zone, hab. session 20.60.63.2-0.60.1-1.10.60.61.11.11.1-1.8-0.20.5-0.4-0.4-0.7-0.20.4-0.50.4-0.7
Time in novel zone, hab. session 20.20.21.10.4-0.10.5-0.4-0.2-0.6-0.5-0.51.00.1-0.10.30.30.3-0.0-0.30.2-0.30.4
Total zone transitions, hab. session 22.22.812.2-0.6-0.21.5-0.0-2.00.2-1.9-1.92.51.5-2.2-1.0-1.02.2-3.51.01.81.0-1.5
Total locomotion distance, hab. session 21.01.37.4-0.1-0.40.8-0.2-1.30.1-1.3-1.31.50.9-1.3-0.6-0.61.4-2.70.61.20.6-1.2
Locomotion velocity, hab. session 20.70.96.60.0-0.80.6-0.6-1.1-0.3-1.0-1.01.50.6-1.1-0.3-0.31.2-2.60.20.80.2-0.9
Novel to familiar place preference ratio1.01.01.9-0.61.11.41.0-0.90.8-1.3-1.31.01.2-1.0-1.1-1.11.0-0.61.01.21.0-0.5
Novelty place preference0.60.61.0-0.50.91.00.8-0.60.7-0.9-0.90.70.9-0.7-0.8-0.80.7-0.40.80.90.8-0.3
Time in novel zone, NPP test0.50.50.9-0.40.80.90.8-0.50.7-0.9-0.90.60.9-0.6-0.8-0.80.6-0.50.80.80.8-0.4
Total zone transitions, NPP test1.82.68.00.10.41.80.3-2.30.3-1.8-1.82.81.5-2.4-1.0-1.02.5-2.20.81.80.8-1.0
Total locomotion distance, NPP test0.30.41.60.20.00.50.1-0.80.3-0.6-0.61.10.6-0.9-0.5-0.50.9-1.30.40.70.4-0.6
Locomotion velocity, NPP test0.60.92.00.20.61.00.6-1.20.6-1.0-1.01.41.0-1.3-0.9-0.91.2-1.10.71.10.7-0.7
Intraocular pressure0.10.10.40.3-0.4-0.0-0.5-0.1-0.70.00.00.6-0.30.00.50.50.00.2-0.5-0.2-0.60.3
Delta distance traveled before/after self-admin1.11.22.1-0.81.21.31.1-1.30.9-1.2-1.20.71.2-1.0-1.0-1.01.4-0.21.11.11.1-1.4
Delta ambulatory time before/after self-admin2.73.04.9-0.81.92.21.7-2.11.3-2.0-2.01.31.9-1.7-1.6-1.62.2-0.31.61.91.6-2.0
Parametrial fat weight0.50.91.40.40.81.00.9-0.80.9-1.1-1.10.91.0-1.0-1.1-1.11.0-0.91.01.21.0-0.6
Pavlov. Cond. lever latency0.00.10.20.30.10.30.1-0.20.0-0.4-0.40.30.2-0.2-0.2-0.20.2-0.40.20.30.2-0.1
Pavlov. Cond. magazine entry latency1.01.33.6-1.91.60.91.6-0.71.6-0.6-0.60.01.3-0.7-1.3-1.30.60.11.30.91.3-0.9
Pavlov. Cond. change in total contacts0.70.81.5-0.71.21.11.1-0.90.9-0.9-0.90.61.1-0.8-0.8-0.80.80.21.00.91.0-0.4
Pavlov. Cond. index score0.50.61.3-1.11.10.71.1-0.71.0-0.4-0.40.10.9-0.7-0.9-0.90.60.20.80.70.8-0.5
Pavlov. Cond. latency score0.10.20.9-0.90.60.10.7-0.20.70.10.1-0.20.4-0.2-0.4-0.40.10.50.40.20.4-0.3
Pavlov. Cond. lever contacts0.00.00.3-0.40.1-0.10.1-0.00.00.20.2-0.2-0.00.00.10.1-0.10.6-0.1-0.1-0.10.0
Pavlov. Cond. magazine entry number1.92.43.91.5-2.0-1.7-1.91.5-1.71.41.4-0.7-1.81.51.71.7-1.40.3-1.7-1.6-1.71.1
Pavlov. Cond. intertrial magazine entries4.04.89.60.01.83.11.4-2.80.9-3.0-3.03.02.3-2.8-1.7-1.72.9-1.41.72.61.7-0.8
Pavlov. Cond. lever-magazine prob. diff.0.60.71.7-1.01.30.91.2-0.81.0-0.6-0.60.21.0-0.8-0.9-0.90.70.50.90.70.9-0.5
Pavlov. Cond. response bias0.50.61.7-1.31.10.81.0-0.70.9-0.6-0.60.10.9-0.6-0.8-0.80.50.20.80.70.8-0.5
Pavlov. Cond. lever latency0.10.10.60.5-0.4-0.1-0.30.4-0.3-0.2-0.2-0.7-0.40.6-0.1-0.1-0.5-0.8-0.2-0.1-0.2-0.1
Pavlov. Cond. magazine entry latency0.70.81.9-0.90.20.90.2-1.20.2-1.1-1.11.31.0-1.3-0.5-0.51.3-1.40.51.00.5-0.7
Pavlov. Cond. change in total contacts0.60.81.6-1.01.30.91.1-0.91.0-0.6-0.60.71.0-1.0-0.7-0.70.90.50.90.81.0-0.3
Pavlov. Cond. index score0.60.81.9-0.90.70.90.6-1.20.6-0.8-0.81.41.0-1.3-0.5-0.51.3-0.30.70.90.7-0.3
Pavlov. Cond. latency score0.80.92.0-1.10.70.90.7-1.20.7-0.8-0.81.41.1-1.4-0.7-0.71.3-0.60.91.00.9-0.5
Pavlov. Cond. lever contacts0.30.41.3-0.60.70.60.6-0.80.6-0.3-0.31.10.8-1.1-0.3-0.31.00.40.50.60.6-0.1
Pavlov. Cond. magazine entry number0.30.30.90.9-0.5-0.6-0.40.7-0.40.50.5-0.7-0.70.80.40.4-0.70.2-0.4-0.5-0.50.2
Pavlov. Cond. intertrial magazine entries0.10.21.21.00.4-0.00.20.2-0.00.10.10.0-0.20.30.10.1-0.31.1-0.1-0.1-0.10.7
Pavlov. Cond. lever-magazine prob. diff.0.70.92.2-0.90.91.10.8-1.30.6-0.9-0.91.51.1-1.4-0.6-0.61.3-0.20.81.00.8-0.4
Pavlov. Cond. response bias0.81.12.0-1.11.01.10.9-1.20.9-0.9-0.91.31.2-1.4-0.8-0.81.3-0.31.01.11.0-0.5
Time in closed arm before self-admin1.11.25.0-2.2-0.6-1.4-0.40.9-0.21.31.3-1.2-0.81.80.50.5-1.80.9-0.5-1.2-0.6-0.0
Time in closed arm after self-admin0.70.76.3-2.51.10.30.8-0.10.5-0.2-0.20.10.50.5-0.5-0.5-0.21.80.5-0.10.5-0.1
Time in open arm before self-admin0.60.76.82.6-0.50.4-0.70.1-0.8-0.3-0.30.4-0.4-0.80.60.61.0-0.4-0.60.2-0.60.6
Time in open arm after self-admin0.80.98.32.9-1.0-0.2-1.10.4-1.10.20.2-0.0-0.80.21.01.0-0.3-0.5-0.9-0.2-0.90.0
Bone: periosteal estimation0.40.93.1-1.21.40.41.6-0.11.8-0.0-0.0-0.11.0-0.3-1.2-1.20.20.41.30.61.3-0.7
Bone: periosteal perimeter0.61.02.7-1.01.60.71.7-0.31.6-0.3-0.30.11.1-0.5-1.2-1.20.40.81.30.71.3-0.6
Bone: post-yield work0.10.10.60.70.1-0.1-0.00.3-0.20.20.2-0.2-0.20.40.20.2-0.40.7-0.2-0.3-0.20.5
Progressive ratio test 1 active lever presses0.20.20.70.1-0.7-0.6-0.50.4-0.20.70.7-0.8-0.50.30.40.4-0.3-0.4-0.5-0.6-0.40.2
Progressive ratio test 1 breakpoint0.20.30.6-0.3-0.8-0.6-0.50.5-0.20.60.6-0.7-0.50.40.40.4-0.4-0.7-0.4-0.6-0.40.2
Progressive ratio test 1 inactive lever presses0.10.21.21.1-0.2-0.3-0.1-0.20.00.50.5-0.7-0.4-0.20.20.20.20.1-0.2-0.2-0.20.3
Progressive ratio test 2 active lever presses0.20.20.50.1-0.7-0.5-0.60.1-0.30.50.5-0.2-0.50.20.40.40.0-0.5-0.5-0.5-0.40.3
Progressive ratio test 2 breakpoint0.20.20.6-0.2-0.8-0.6-0.60.2-0.40.60.6-0.3-0.60.50.50.5-0.3-0.3-0.6-0.7-0.50.4
Progressive ratio test 2 inactive lever presses0.30.30.8-0.9-0.4-0.7-0.20.70.10.90.9-0.5-0.60.70.30.3-0.70.1-0.3-0.8-0.30.3
Incentive Sensitization - Responses0.10.10.2-0.1-0.3-0.3-0.20.1-0.00.30.3-0.3-0.30.30.10.1-0.1-0.4-0.2-0.3-0.1-0.0
Incentive Sensitization - Breakpoint0.10.10.2-0.2-0.4-0.5-0.20.3-0.00.50.5-0.5-0.40.50.10.1-0.3-0.3-0.3-0.5-0.10.0
Sum of active levers in priming session hrs 5-64.94.823.04.8-2.6-2.4-2.22.3-1.52.62.6-1.4-2.30.52.12.1-0.4-0.2-2.1-1.7-2.11.2
Progressive ratio0.30.41.00.90.00.8-0.3-0.8-0.6-1.0-1.00.40.4-0.80.30.30.7-0.2-0.20.7-0.2-0.8
Food seeking constrained by brief footshock0.20.30.8-0.20.4-0.40.70.70.80.80.8-0.9-0.10.3-0.3-0.3-0.40.70.3-0.30.30.3
Seeking ratio, punishment vs. effort1.31.64.5-0.7-0.3-1.70.11.90.62.12.1-1.5-1.11.70.20.2-1.61.2-0.2-1.6-0.21.2
Retroperitoneal fat weight0.10.42.7-1.60.1-0.10.40.40.9-0.0-0.0-0.20.5-0.3-0.8-0.80.2-1.20.70.20.7-0.6
Reaction time number correct2.43.59.52.0-2.7-1.2-2.90.5-3.10.60.60.7-1.80.62.62.6-0.4-0.1-2.5-1.3-2.41.5
Reaction time mean minus median2.12.85.8-0.90.81.90.6-2.40.4-2.3-2.31.91.6-2.1-1.2-1.22.2-2.11.11.91.2-1.3
Reaction time mean minus median AUC0.40.51.9-0.4-0.10.7-0.2-1.2-0.4-1.1-1.11.40.5-0.9-0.1-0.11.0-0.80.10.80.2-0.3
Reaction time num false alarms0.10.20.5-0.30.20.7-0.1-0.6-0.4-0.7-0.70.40.2-0.4-0.0-0.00.50.10.00.4-0.1-0.2
Reaction time num false alarms AUC0.10.20.7-0.1-0.20.5-0.5-0.5-0.8-0.6-0.60.5-0.0-0.20.30.30.30.2-0.30.1-0.40.2
Reaction time trials correct on left2.43.59.52.0-2.7-1.2-2.90.5-3.10.60.60.7-1.80.62.62.6-0.4-0.1-2.5-1.3-2.41.5
Reaction time trials on left2.33.29.31.9-2.6-1.1-2.90.4-3.00.50.50.8-1.70.52.62.6-0.3-0.2-2.4-1.2-2.31.5
Reaction time mean1.11.66.1-0.00.31.10.4-1.60.5-1.6-1.61.51.0-1.3-1.1-1.11.4-2.51.01.51.0-1.0
Reaction time mean AUC0.91.25.2-0.20.20.80.3-1.30.5-1.3-1.31.30.9-1.0-1.0-1.01.1-2.30.91.30.9-0.9
Median of all reaction times0.91.35.90.20.30.90.4-1.20.6-1.4-1.41.20.9-1.0-1.1-1.11.1-2.41.01.41.0-1.0
Reaction time omissions1.52.15.4-1.20.61.50.5-1.70.4-2.1-2.11.61.5-1.5-1.2-1.21.5-2.31.21.61.1-1.0
Reaction time false alarm rate0.50.71.8-1.41.21.01.1-0.61.0-0.7-0.7-0.10.9-0.5-1.1-1.10.40.11.00.70.9-0.7
Reaction time premature initiation rate0.50.61.50.1-0.5-1.0-0.60.4-0.70.90.9-1.0-0.80.51.11.1-0.51.2-0.9-0.9-0.80.3
Reaction time premature initiations1.52.25.41.3-1.8-1.3-2.00.4-2.20.90.9-0.3-1.50.62.32.3-0.50.9-2.0-1.3-1.91.0
Std. dev. reaction times1.42.04.3-0.50.61.60.5-2.10.3-2.0-2.01.61.3-1.8-1.1-1.11.8-1.90.91.71.0-1.0
Reaction time trials completed2.33.29.31.9-2.6-1.1-2.90.4-3.00.50.50.8-1.70.52.62.6-0.3-0.2-2.4-1.2-2.31.5
Reaction time trials AUC2.23.19.32.2-2.5-0.9-2.80.2-3.10.40.40.9-1.60.42.52.5-0.1-0.1-2.4-1.1-2.31.5
Run reversals in cocaine runway, females0.20.20.90.7-0.3-0.1-0.40.0-0.60.40.40.2-0.50.10.60.60.10.9-0.6-0.4-0.60.4
Run reversals in cocaine runway, males0.70.61.6-0.81.20.61.2-0.31.2-0.4-0.4-0.40.7-0.1-1.0-1.0-0.10.41.00.61.0-0.8
Latency to leave start box in cocaine runway0.91.02.61.3-0.9-0.4-1.30.2-1.60.30.30.1-1.00.71.41.4-0.41.0-1.4-0.6-1.40.0
Latency to leave start box in cocaine runway, F1.01.12.6-0.4-0.9-0.6-1.30.4-1.60.40.4-0.3-1.11.41.41.4-1.01.2-1.3-1.0-1.30.4
Latency to leave start box in cocaine runway, M0.70.76.22.50.20.70.1-0.8-0.0-0.5-0.50.90.2-1.1-0.1-0.11.3-0.3-0.00.8-0.0-0.9
Std. dev. time between licks in bursts1.61.92.8-0.71.21.41.3-1.41.3-1.4-1.41.21.6-1.4-1.4-1.41.4-1.21.61.71.6-0.9
Total sessions with >9 infusions0.30.31.90.4-0.90.1-0.9-0.4-0.8-0.3-0.30.3-0.2-0.30.50.50.5-1.4-0.3-0.1-0.40.1
Short access day 1 total inactive lever presses0.80.81.6-0.71.30.91.3-0.81.2-0.8-0.80.81.0-0.8-1.1-1.10.70.01.10.91.10.1
Short access day 10 total inactive lever presses1.01.22.00.8-1.0-1.3-0.81.2-0.61.41.4-0.6-1.31.11.01.0-1.20.7-1.0-1.2-1.01.1
Short access day 1 total infusions0.30.41.3-0.50.20.60.3-0.50.4-0.6-0.61.00.6-0.8-0.5-0.50.8-1.10.50.50.50.4
Short access day 10 total infusions0.40.51.20.2-1.1-0.7-0.80.5-0.40.90.9-0.9-0.70.20.70.7-0.1-0.7-0.7-0.8-0.70.8
Short access total infusions0.10.11.1-0.3-0.5-0.2-0.3-0.10.00.30.3-0.2-0.1-0.30.10.10.4-1.0-0.1-0.2-0.10.3
Short access day 1 locomotion0.40.41.01.0-0.9-0.3-1.0-0.1-1.00.20.20.2-0.6-0.10.80.80.3-0.6-0.6-0.4-0.80.5
Short access day 10 total locomotion1.71.99.33.0-1.5-1.3-1.50.6-1.41.21.2-0.0-1.40.81.51.5-0.70.5-1.4-1.0-1.51.5
Short access total locomotion1.01.12.21.5-1.5-0.9-1.50.2-1.30.80.80.2-1.10.51.21.2-0.4-0.5-1.2-0.9-1.21.4
One hour access (0.3 mA shock)0.20.20.8-0.20.20.00.5-0.10.80.20.2-0.40.10.1-0.5-0.50.1-0.90.50.10.5-0.7
Compulsive drug intake0.70.77.42.7-0.6-0.6-0.50.6-0.50.60.6-0.7-0.90.40.60.6-0.30.3-0.5-0.4-0.60.2
One hour access (shock baseline)0.20.31.0-0.90.50.10.7-0.01.00.20.2-0.40.40.0-0.6-0.60.1-0.40.60.10.6-0.4
Social response proportion2.02.13.81.4-0.9-1.7-0.81.8-0.81.81.8-1.6-1.51.51.41.4-1.51.9-1.2-1.5-1.31.3
Social responses2.33.04.71.4-1.8-2.2-1.62.0-1.32.02.0-1.1-1.91.71.91.9-1.71.1-1.7-1.8-1.61.6
Social time0.00.10.30.2-0.3-0.4-0.10.30.00.30.30.2-0.20.10.20.2-0.1-0.1-0.0-0.10.10.6
Soleus weight0.82.24.1-2.01.11.51.2-1.31.3-1.6-1.60.71.6-1.5-1.5-1.51.5-1.81.61.51.5-1.5
Bone: stiffness0.30.51.7-0.91.00.41.20.11.3-0.2-0.2-0.40.7-0.2-1.0-1.00.1-0.11.00.41.0-0.6
Tibialis anterior weight0.51.62.4-1.31.41.41.4-1.41.3-1.1-1.10.61.4-1.5-1.4-1.41.5-0.31.31.31.3-1.1
Time to tail flick, vehicle, before self-admin1.01.02.4-1.4-0.3-1.2-0.11.5-0.01.21.2-0.9-0.91.60.30.3-1.41.3-0.4-1.3-0.50.5
Time to tail flick, vehicle, after self-admin0.70.72.5-0.5-0.3-1.3-0.21.00.01.21.2-1.6-1.01.10.40.4-0.70.9-0.2-1.1-0.40.4
Time to tail flick, test, before self-admin1.81.88.2-2.92.00.82.0-0.51.8-0.5-0.5-0.11.3-0.1-1.4-1.40.31.31.60.81.5-0.3
Time to tail flick, test, after self-admin1.31.43.2-1.21.60.81.7-0.41.8-0.6-0.60.71.3-1.0-1.5-1.50.70.21.61.01.5-0.5
Delta time to tail flick, vehicle, before/after SA1.01.02.70.30.81.10.7-1.70.6-1.1-1.10.70.9-1.4-0.7-0.71.6-0.80.91.10.8-0.6
Delta time to tail flick, test, before/after SA0.10.11.51.2-0.1-0.2-0.00.40.00.20.20.2-0.1-0.30.00.00.2-0.0-0.1-0.0-0.1-0.2
Tibia length0.30.82.9-1.70.8-0.31.10.51.50.50.5-1.30.60.4-1.0-1.0-0.50.20.80.00.8-1.0
Ambulatory time before self-admin1.51.63.2-0.1-0.9-1.6-0.81.6-0.61.71.7-1.4-1.31.61.01.0-1.81.2-1.0-1.5-1.10.9
Ambulatory time after self-admin0.20.21.1-0.40.2-0.10.10.1-0.10.40.4-0.7-0.20.50.10.1-0.01.1-0.0-0.3-0.3-0.7
Bone: tissue strength0.90.92.90.5-1.7-0.9-1.50.7-1.30.50.5-0.3-0.90.71.01.0-0.5-1.1-1.1-0.8-1.10.1
Total heroin consumption6.17.216.34.0-2.4-2.5-2.62.6-2.82.72.7-0.8-2.82.03.03.0-1.83.0-3.1-2.4-3.02.3
Bone: trabecular number0.20.40.8-0.1-0.7-0.9-0.50.7-0.30.80.8-0.6-0.60.70.40.4-0.70.1-0.6-0.8-0.60.1
Bone: trabecular spacing0.10.10.50.7-0.30.2-0.4-0.1-0.5-0.3-0.30.1-0.1-0.10.20.20.2-0.2-0.20.1-0.20.0
Bone: trabecular thickness1.51.84.5-2.11.61.21.6-1.31.6-1.0-1.00.71.5-1.2-1.6-1.61.0-0.61.51.31.5-0.9
Bone: trabecular tissue density0.50.82.7-0.3-1.0-1.3-0.51.60.00.90.9-1.1-0.51.40.20.2-1.5-1.0-0.2-0.7-0.2-0.3
Water consumed over 24 hours0.50.62.7-1.7-1.0-0.9-0.80.6-0.60.80.8-0.6-0.50.50.70.7-0.6-0.3-0.7-0.8-0.70.0
Number of responses in last shaping day1.92.03.8-0.62.01.41.9-1.31.7-1.3-1.31.01.7-1.5-1.6-1.61.20.21.61.51.6-0.4