Hub : Genes

Pde8a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative polyA XM_006229438.4 0.06 0.04 2.0e-04 0.01 0.03 0.04 0.02 2.8e-02 4.1e-04 8.1e-05 1.2e-03
2 PL alternative polyA XM_006229438.4 0.06 0.04 5.7e-04 0.01 0.02 0.04 0.02 1.6e-02 1.4e-03 5.5e-05 1.1e-03
3 Liver mRNA stability Pde8a 0.04 0.03 2.0e-03 0.01 0.02 0.01 0.01 2.2e-02 6.2e-03 3.1e-02 1.2e-02
4 PL isoform ratio XM_006229438.4 0.05 0.03 1.2e-03 0.01 0.02 0.03 0.02 8.7e-03 2.3e-03 5.4e-04 2.2e-03
5 PL alternative polyA XM_006229439.4 0.05 0.03 1.3e-03 0 0.01 -0 0 3.2e-01 1.0e-02 4.6e-01 1.2e-01
6 Brain alternative polyA XM_006229438.4 0.17 0.07 5.0e-16 0.18 0.18 0.19 0.19 2.2e-16 5.3e-17 4.6e-17 1.2e-17
7 Brain alternative polyA XM_006229438.4 0.18 0.07 2.2e-16 0.18 0.19 0.19 0.2 1.6e-16 1.2e-17 4.4e-17 3.2e-18
8 Brain alternative polyA XM_006229439.4 0.1 0.05 4.6e-08 0.1 0.09 0.09 0.1 1.0e-09 9.4e-09 8.4e-09 2.5e-09
9 Liver alternative polyA XM_006229438.4 0.23 0.1 0.0e+00 0.17 0.18 0.17 0.17 9.1e-19 4.2e-19 4.7e-18 8.5e-19
10 Liver gene expression Pde8a 0.11 0.06 6.6e-08 0.02 0.06 0.06 0.05 1.9e-03 3.9e-07 9.3e-07 2.4e-06
11 Liver isoform ratio XM_039113042.1 0.03 0.02 3.5e-03 0.02 0.01 0.01 0.01 1.9e-03 2.4e-02 2.0e-02 9.0e-03
12 pVTA alternative polyA XM_006229438.4 0.13 0.08 5.5e-03 0.06 -0 0.02 0.03 1.8e-03 6.1e-01 5.5e-02 2.1e-02
13 Liver alternative polyA XM_006229439.4 0.22 0.1 0.0e+00 0.17 0.16 0.16 0.16 4.4e-18 2.4e-17 3.2e-17 1.1e-17
14 Liver alternative polyA XM_006229438.4 0.24 0.11 0.0e+00 0.18 0.18 0.17 0.18 4.2e-20 4.7e-20 8.5e-19 8.2e-20
15 Liver alternative polyA XM_006229439.4 0.21 0.1 6.7e-16 0.15 0.14 0.14 0.14 4.4e-16 2.7e-15 1.6e-15 1.7e-15
16 Liver isoform ratio XM_006229438.4 0.2 0.09 1.7e-16 0.15 0.15 0.14 0.15 1.1e-16 1.2e-16 2.1e-15 2.0e-16
17 Brain isoform ratio XM_006229438.4 0.18 0.08 1.7e-16 0.19 0.19 0.18 0.2 3.9e-17 1.1e-17 7.6e-17 2.4e-18
18 Adipose gene expression Pde8a 0.1 0.06 1.6e-08 0.04 0.06 0.06 0.05 1.7e-05 1.2e-07 1.8e-07 1.4e-06
19 BLA alternative polyA NM_198767.1 0.06 0.04 3.1e-03 0.06 0.05 0.04 0.05 3.6e-04 1.7e-03 3.0e-03 1.7e-03
20 Brain isoform ratio XM_006229439.4 0.04 0.03 2.0e-03 0.01 0.01 0.01 0.01 2.0e-02 1.6e-02 2.3e-02 3.9e-02
21 NAcc isoform ratio XM_006229438.4 0.05 0.03 7.1e-05 0.02 0.04 0.04 0.03 3.9e-03 2.1e-05 5.1e-05 1.5e-04
22 NAcc alternative polyA XM_006229438.4 0.06 0.04 3.2e-05 0.04 0.04 0.04 0.04 1.7e-05 1.4e-05 5.5e-05 5.2e-05
23 NAcc alternative polyA XM_006229438.4 0.06 0.04 2.2e-05 0.04 0.04 0.04 0.04 3.1e-05 1.1e-05 6.3e-05 5.1e-05
24 BLA alternative polyA XM_006229439.4 0.11 0.06 1.5e-05 0.11 0.11 0.11 0.1 2.4e-06 2.7e-06 2.4e-06 3.7e-06
25 Brain intron excision ratio chr1_135236813_135245054 0.03 0.02 1.0e-02 0.01 0.01 -0 0 6.4e-02 3.6e-02 4.8e-01 1.7e-01
26 BLA alternative polyA XM_006229439.4 0.13 0.07 4.6e-06 0.12 0.12 0.11 0.12 8.2e-07 7.6e-07 1.4e-06 9.3e-07
27 Brain alternative polyA XM_006229439.4 0.1 0.05 1.4e-08 0.1 0.11 0.1 0.11 2.7e-09 3.4e-10 2.8e-09 1.5e-10

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density1.01.66.02.22.1-2.42.12.2-1.1-1.1-1.0-1.6-0.7-1.31.3-1.31.3-1.31.3-0.7-0.1-1.00.6-0.6-0.3-0.30.10.1-0.20.0
Area under the delay curve0.10.10.7-0.1-0.10.3-0.2-0.3-0.1-0.1-0.00.2-0.70.2-0.20.2-0.20.2-0.2-0.0-0.80.4-0.30.20.20.2-0.40.40.40.0
BMI with tail0.93.113.3-3.2-2.83.6-2.5-2.80.91.00.91.53.21.5-1.51.5-1.31.3-1.30.12.31.20.7-0.3-1.1-0.9-0.7-0.10.60.0
BMI without tail1.63.47.6-2.8-2.52.8-2.6-2.71.71.81.92.30.62.3-2.32.3-2.32.3-2.31.40.10.6-1.31.41.01.10.2-0.4-0.10.0
Body weight0.31.45.3-0.00.11.40.3-0.4-1.4-1.3-1.4-0.60.5-0.30.3-0.50.6-0.60.6-1.6-0.22.01.3-1.3-1.5-1.5-2.31.62.00.0
Weight adjusted by age0.30.41.51.21.1-1.11.00.9-0.6-0.6-0.6-0.6-0.2-0.50.5-0.50.5-0.50.5-0.30.0-0.80.1-0.10.10.00.3-0.3-0.40.0
Bone surface0.61.16.11.81.6-2.51.41.7-0.1-0.10.1-0.7-1.8-0.60.6-0.70.7-0.70.70.5-1.1-1.3-0.70.51.00.91.0-0.4-1.00.0
Bone volume0.61.05.21.81.7-2.31.51.7-0.4-0.4-0.3-0.8-1.5-0.60.6-0.70.7-0.70.70.2-1.0-1.1-0.40.20.70.60.6-0.2-0.60.0
Breakpoint value in progressive ratio session0.30.40.8-0.7-0.70.8-0.8-0.80.50.50.70.6-0.70.6-0.60.6-0.60.6-0.60.4-0.90.8-0.60.50.40.5-0.30.40.40.0
Number of licking bursts0.20.31.20.80.7-1.10.70.6-0.0-0.0-0.1-0.2-0.60.1-0.10.1-0.10.1-0.10.1-0.2-0.9-0.50.40.60.60.6-0.5-0.70.0
Context. condit. distance diff. score0.10.20.90.50.4-0.90.30.50.30.20.3-0.1-0.7-0.10.1-0.10.1-0.10.10.4-0.3-0.3-0.50.40.60.60.6-0.4-0.60.0
Locomotion velocity, session 10.40.41.4-1.1-1.21.1-1.1-1.00.90.80.80.80.40.3-0.30.5-0.50.5-0.50.70.20.2-0.40.40.20.20.3-0.2-0.20.0
Locomotion distance, session 10.10.10.6-0.2-0.20.2-0.3-0.30.30.30.40.3-0.80.0-0.00.1-0.10.1-0.10.4-0.80.2-0.50.40.40.5-0.00.20.10.0
Locomotion velocity, session 20.10.10.80.0-0.10.5-0.1-0.4-0.2-0.1-0.10.1-0.40.0-0.00.1-0.10.1-0.1-0.2-0.50.9-0.1-0.0-0.0-0.0-0.50.40.50.0
Locomotion distance, session 20.00.10.50.20.2-0.20.1-0.0-0.0-0.00.10.2-0.7-0.00.00.1-0.10.1-0.10.2-0.60.1-0.30.30.40.40.10.1-0.00.0
Locomotion velocity, session 31.31.53.6-0.6-0.60.1-1.0-0.81.31.31.31.4-1.71.1-1.11.2-1.21.2-1.21.6-1.5-0.4-1.91.71.91.91.0-0.5-0.90.0
Locomotion distance, session 32.52.76.3-0.8-1.00.2-1.3-1.11.81.81.81.8-2.21.4-1.41.5-1.51.5-1.52.2-2.0-0.4-2.52.32.52.51.4-0.7-1.10.0
Stereotopy head waving bouts, day 32.93.47.92.72.7-2.82.72.8-1.9-2.0-1.9-2.4-0.3-2.12.1-2.02.0-2.02.0-1.50.3-0.81.6-1.5-1.1-1.2-0.40.50.20.0
Stereotopy head waving duration, day 31.01.22.3-0.9-1.00.3-0.9-0.81.21.21.21.11.01.1-1.11.2-1.21.2-1.21.21.2-1.3-0.81.00.90.91.4-1.5-1.40.0
Locomotion velocity, session 71.41.54.2-1.9-1.71.8-2.0-1.91.31.31.41.6-0.70.9-0.91.0-1.01.0-1.01.2-1.11.2-1.21.10.91.00.10.30.20.0
Locomotion distance, session 71.01.22.2-1.3-1.21.1-1.5-1.41.21.31.31.4-0.51.1-1.11.2-1.21.2-1.21.2-0.60.3-1.31.31.21.20.5-0.3-0.40.0
Stereotopy head waving bouts, day 70.40.53.31.01.0-1.60.91.2-0.1-0.1-0.1-0.5-0.0-0.40.4-0.20.2-0.20.20.20.4-1.80.00.10.30.30.9-0.7-1.00.0
Stereotopy head waving duration, day 70.50.72.0-0.4-0.5-0.2-0.5-0.30.90.90.90.80.00.7-0.70.8-0.80.8-0.81.10.3-1.4-0.90.90.90.91.2-1.0-1.10.0
Locomotion velocity, session 81.82.15.2-2.3-2.22.2-2.3-2.31.61.61.71.90.51.5-1.51.5-1.51.5-1.51.20.20.6-1.11.20.80.90.6-0.6-0.40.0
Locomotion distance, session 80.20.31.90.90.9-1.20.70.7-0.1-0.20.1-0.3-1.4-0.40.4-0.30.3-0.30.30.1-1.1-0.0-0.50.40.70.60.40.1-0.30.0
Degree of sensitization distance0.30.31.9-0.5-0.40.8-0.2-0.3-0.2-0.2-0.2-0.01.40.2-0.20.2-0.20.2-0.2-0.51.20.20.6-0.5-0.7-0.7-0.5-0.00.30.0
Degree of sensitization stereotypy0.10.11.00.10.2-0.40.10.30.10.10.1-0.00.2-0.10.1-0.00.0-0.00.00.20.3-1.00.00.10.10.10.5-0.4-0.40.0
Conditioned locomotion1.21.42.11.01.2-0.71.11.2-1.3-1.4-1.3-1.4-0.0-1.41.4-1.41.4-1.41.4-1.4-0.10.41.3-1.4-1.3-1.3-1.21.11.10.0
Cocaine response after cond. corrected0.50.61.50.00.10.30.20.2-0.6-0.7-0.6-0.61.0-0.80.8-0.90.9-0.90.9-0.80.70.41.1-1.1-1.2-1.2-0.70.50.70.0
Cocaine response after cond. not corrected0.20.20.7-0.3-0.30.6-0.2-0.2-0.2-0.2-0.2-0.20.8-0.50.5-0.50.5-0.50.5-0.40.50.60.7-0.7-0.8-0.8-0.40.40.50.0
Cocaine response before conditioning0.20.31.40.50.4-0.80.20.40.30.30.30.1-1.20.1-0.10.1-0.10.1-0.10.5-0.9-0.2-0.80.70.90.90.6-0.2-0.50.0
Saline control response1.31.79.3-0.6-0.70.8-1.1-1.10.91.01.01.3-2.90.9-0.90.9-0.90.9-0.91.1-3.11.1-1.91.51.71.7-0.30.90.50.0
Bone: connectivity density1.11.86.42.12.0-2.52.02.3-0.9-1.1-0.9-1.7-0.2-1.41.4-1.61.6-1.61.6-0.60.4-1.20.8-0.8-0.4-0.50.3-0.1-0.40.0
Bone: cortical apparent density0.81.14.5-0.9-0.81.8-0.6-0.8-0.6-0.5-0.5-0.21.0-0.60.6-0.60.6-0.60.6-1.20.32.11.2-1.2-1.5-1.5-1.61.31.60.0
Bone: cortical area2.13.210.32.82.7-2.62.42.4-1.6-1.6-1.4-1.7-3.2-1.71.7-1.81.8-1.81.8-0.9-2.80.40.1-0.50.10.0-0.81.50.90.0
Bone: cortical porosity0.50.62.2-0.4-0.4-0.0-0.3-0.20.60.60.70.51.30.7-0.70.7-0.70.7-0.70.61.5-1.4-0.10.40.30.31.1-1.3-1.10.0
Bone: cortical porosity0.60.72.3-0.4-0.3-0.2-0.3-0.20.70.60.80.51.10.8-0.80.8-0.80.8-0.80.61.4-1.5-0.30.60.50.51.2-1.4-1.30.0
Bone: cortical thickness1.21.93.01.71.7-1.31.61.5-1.4-1.4-1.2-1.4-1.7-1.61.6-1.61.6-1.61.6-1.1-1.70.90.7-1.0-0.6-0.7-1.21.61.30.0
Bone: cortical thickness2.12.44.31.21.4-0.71.51.4-1.8-1.8-1.7-1.80.7-1.81.8-1.81.8-1.81.8-1.90.60.82.1-2.0-1.9-1.9-1.41.21.30.0
Bone: cortical tissue density0.91.14.3-0.9-0.71.7-0.6-0.8-0.6-0.6-0.6-0.31.1-0.70.7-0.60.6-0.60.6-1.20.52.11.2-1.3-1.6-1.5-1.51.21.60.0
Condit. Reinf. active minus inactive responses0.91.01.60.80.8-0.40.80.8-1.1-1.1-1.1-1.0-0.7-1.31.3-1.21.2-1.21.2-1.0-0.80.80.9-1.0-0.9-0.9-1.11.31.20.0
Condit. Reinf. active-inactive response ratio0.40.42.30.90.9-1.40.70.9-0.1-0.0-0.0-0.2-1.5-0.20.2-0.10.1-0.10.10.4-1.2-0.8-0.70.50.90.80.4-0.1-0.40.0
Condit. Reinf. active responses1.21.52.20.91.0-0.31.00.9-1.5-1.5-1.4-1.2-0.1-1.51.5-1.31.3-1.31.3-1.4-0.30.81.4-1.4-1.4-1.4-1.41.41.40.0
Condit. Reinf. inactive responses0.40.51.30.00.10.60.2-0.0-0.8-0.8-0.6-0.50.8-0.60.6-0.50.5-0.50.5-0.90.50.81.0-1.0-1.2-1.1-1.00.70.90.0
Incentive salience index mean1.21.53.90.50.50.30.50.4-1.3-1.3-1.1-0.9-1.1-1.31.3-1.31.3-1.31.3-1.3-1.51.80.9-1.2-1.1-1.1-1.82.01.90.0
Condit. Reinf. lever presses1.41.99.4-0.5-0.41.9-0.5-0.9-1.2-1.0-0.8-0.2-0.9-0.70.7-0.70.7-0.70.7-1.3-1.83.10.8-1.1-1.2-1.2-2.42.52.60.0
Condit. Reinf. active minus inactive responses0.20.30.8-0.00.10.30.10.1-0.5-0.5-0.5-0.40.2-0.60.6-0.70.7-0.70.7-0.6-0.00.90.7-0.7-0.7-0.7-0.70.70.70.0
Condit. Reinf. active-inactive response ratio0.60.61.60.00.20.10.30.4-0.7-0.7-0.7-0.71.3-0.80.8-0.80.8-0.80.8-0.81.10.31.3-1.1-1.3-1.2-0.60.40.50.0
Condit. Reinf. active responses0.20.32.00.00.00.4-0.1-0.2-0.3-0.2-0.30.0-1.2-0.20.2-0.30.3-0.30.3-0.2-1.41.3-0.1-0.1-0.0-0.0-0.81.00.90.0
Condit. Reinf. inactive responses1.21.510.9-0.2-0.30.5-0.7-0.80.50.60.61.0-3.10.6-0.60.5-0.50.5-0.50.9-3.31.5-1.71.21.51.5-0.51.10.70.0
Condit. Reinf. lever presses3.44.67.6-2.4-2.42.0-2.7-2.62.42.52.52.8-1.12.4-2.42.3-2.32.3-2.32.4-1.20.3-2.52.42.32.31.3-0.9-1.00.0
Condit. Reinf. lever reinforcers received0.40.53.5-0.00.00.5-0.2-0.3-0.3-0.2-0.20.1-1.6-0.30.3-0.30.3-0.30.3-0.2-1.91.6-0.3-0.00.10.1-0.91.31.10.0
Conditioned reinforcement - actives0.50.51.20.90.9-0.51.00.7-1.0-1.0-1.1-0.71.0-0.50.5-0.50.5-0.50.5-1.01.1-0.40.9-0.7-0.7-0.7-0.3-0.2-0.00.0
Conditioned reinforcement - inactives3.64.111.33.43.2-2.33.02.4-2.9-2.8-2.9-2.1-0.7-2.12.1-2.12.1-2.12.1-2.2-0.4-0.51.2-1.2-0.8-0.9-1.00.70.50.0
Conditioned locomotion0.40.51.61.01.0-0.41.10.6-1.1-1.0-1.2-0.61.2-0.20.2-0.20.2-0.20.2-1.01.3-0.40.9-0.6-0.7-0.7-0.3-0.3-0.10.0
Patch foraging indifference point 0 sec0.40.62.7-0.0-0.1-0.0-0.3-0.30.40.50.60.7-1.60.7-0.70.7-0.70.7-0.70.9-1.60.1-1.21.01.21.10.10.1-0.10.0
Patch foraging indifference point AUC0.91.05.72.01.8-2.41.71.8-0.6-0.6-0.5-0.9-0.8-0.50.5-0.60.6-0.60.6-0.1-0.1-1.3-0.10.20.60.50.8-0.7-1.00.0
Delay disc. indifference point, 0s delay1.01.11.81.11.1-0.91.21.2-1.1-1.2-1.3-1.30.1-1.41.4-1.41.4-1.41.4-1.00.20.01.1-1.1-1.0-1.0-0.60.60.50.0
Delay disc. indifference point, 16s delay0.20.20.5-0.3-0.20.2-0.3-0.40.20.30.50.5-0.40.7-0.70.7-0.70.7-0.70.4-0.3-0.1-0.60.60.60.60.2-0.2-0.20.0
Delay disc. indifference point, 2s delay0.91.01.8-0.9-1.00.6-1.1-1.01.31.41.21.2-0.51.2-1.21.2-1.21.2-1.21.3-0.5-0.3-1.31.21.11.10.7-0.7-0.70.0
Delay disc. indifference point, 24s delay0.20.20.60.80.7-0.30.70.4-0.8-0.7-0.2-0.3-0.5-0.10.1-0.10.1-0.10.1-0.6-0.50.30.1-0.1-0.0-0.0-0.40.40.30.0
Delay disc. indifference point, 4s delay0.70.85.5-0.2-0.20.9-0.4-0.7-0.2-0.00.00.5-2.00.4-0.40.4-0.40.4-0.40.0-2.41.5-0.80.50.60.6-1.11.31.20.0
Delay disc. indifference point, 8s delay0.10.10.3-0.2-0.10.4-0.1-0.2-0.4-0.3-0.2-0.00.10.1-0.10.1-0.10.1-0.1-0.4-0.00.40.3-0.3-0.3-0.3-0.50.40.50.0
Indifference point function ln k1.92.67.1-2.7-2.52.6-2.5-2.41.71.81.72.00.81.8-1.81.8-1.81.8-1.81.40.30.3-1.01.00.60.70.3-0.5-0.20.0
Indifference point function log k1.92.67.1-2.7-2.52.6-2.5-2.41.71.81.72.00.81.8-1.81.8-1.81.8-1.81.40.30.3-1.01.00.60.70.3-0.5-0.20.0
Patch foraging total patch changes 0 sec0.60.92.3-0.2-0.3-0.1-0.5-0.40.80.91.00.9-1.51.0-1.01.0-1.01.0-1.01.3-1.3-0.4-1.51.31.51.50.6-0.4-0.60.0
Patch foraging total patch changes 12 sec3.03.914.83.53.3-3.83.23.3-1.8-1.8-1.7-2.2-1.9-1.91.9-1.91.9-1.91.9-1.0-1.1-1.50.5-0.60.10.00.20.3-0.30.0
Patch foraging total patch changes 18 sec1.41.77.22.62.4-2.72.22.2-1.2-1.2-1.1-1.3-1.9-0.90.9-1.01.0-1.01.0-0.4-1.2-0.8-0.1-0.00.50.40.10.2-0.30.0
Patch foraging total patch changes 24 sec0.70.95.11.81.5-1.71.31.1-0.5-0.5-0.4-0.5-2.3-0.10.1-0.20.2-0.20.20.2-1.8-0.3-0.80.61.11.00.20.1-0.30.0
Patch foraging total patch changes 6 sec0.60.95.21.61.5-1.61.21.2-0.6-0.6-0.4-0.6-2.3-0.60.6-0.70.7-0.70.70.1-1.9-0.0-0.60.30.80.7-0.20.60.10.0
Patch foraging time to switch 0 sec0.71.13.51.71.7-1.71.41.5-1.1-1.0-1.1-1.1-1.9-1.01.0-0.90.8-0.80.8-0.7-1.5-0.10.1-0.20.20.2-0.40.80.40.0
Patch foraging water rate 0 sec0.81.34.3-1.8-1.71.8-1.5-1.51.11.11.21.12.11.2-1.21.2-1.11.1-1.10.61.8-0.1-0.10.3-0.2-0.10.4-0.9-0.50.0
Patch foraging water rate 12 sec3.14.721.6-4.0-3.74.6-3.5-3.71.61.71.72.32.22.0-2.01.8-1.91.9-1.90.81.12.2-0.20.3-0.5-0.4-1.00.31.00.0
Patch foraging water rate 18 sec3.95.314.2-3.8-3.63.7-3.4-3.52.42.52.52.62.22.5-2.52.4-2.52.5-2.51.71.60.7-1.01.10.40.60.6-1.1-0.50.0
Patch foraging water rate 24 sec1.01.36.4-2.1-2.12.5-1.8-1.90.80.80.91.01.80.8-0.80.7-0.70.7-0.70.11.11.10.2-0.2-0.7-0.6-0.50.00.50.0
Patch foraging water rate 6 sec1.82.712.6-3.1-2.83.5-2.5-2.71.11.11.11.52.51.3-1.31.2-1.21.2-1.20.21.71.60.4-0.2-0.9-0.8-0.70.10.70.0
Seeking ratio, delayed vs. immediate footshock10.412.019.33.13.2-2.03.43.3-3.8-4.0-4.4-3.90.9-4.44.4-4.44.2-4.24.2-3.80.81.54.0-4.0-3.9-3.9-2.82.52.50.0
Distance traveled before self-admin2.32.47.61.41.3-0.51.10.9-1.6-1.5-1.6-1.1-2.5-1.71.7-1.71.7-1.71.7-1.2-2.81.80.3-0.8-0.5-0.5-1.82.31.90.0
Distance traveled after self-admin3.13.49.63.12.8-2.12.42.1-2.2-2.1-2.2-1.7-3.0-1.81.8-1.81.8-1.81.8-1.4-2.80.30.1-0.50.1-0.0-1.41.71.20.0
Extensor digitorum longus weight0.20.72.3-1.4-1.41.5-1.4-1.40.80.80.51.00.20.9-0.90.8-0.80.8-0.80.6-0.10.8-0.50.50.30.3-0.10.00.20.0
Bone: elastic displacement4.04.610.50.81.00.31.41.1-2.3-2.3-2.2-2.22.1-2.22.2-2.22.2-2.22.2-2.81.61.73.1-3.0-3.2-3.2-2.31.72.20.0
Bone: elastic work1.41.83.00.60.80.10.80.7-1.5-1.5-1.3-1.30.3-1.51.5-1.51.5-1.51.5-1.6-0.01.51.6-1.7-1.7-1.7-1.71.61.70.0
Bone: endosteal estimation1.02.211.72.22.0-3.41.82.10.10.00.2-0.6-1.8-0.10.1-0.10.1-0.10.10.9-0.7-2.7-1.11.11.81.62.0-1.3-2.00.0
Bone: endosteal perimeter0.81.79.72.42.2-3.12.12.3-0.6-0.6-0.7-1.2-1.6-0.90.9-0.90.9-0.90.90.1-0.8-1.7-0.20.20.70.61.0-0.4-1.00.0
Epididymis fat weight1.63.78.00.30.60.90.80.4-2.1-2.1-2.1-1.61.5-1.81.8-1.92.0-2.02.0-2.60.82.12.7-2.6-2.8-2.8-2.42.02.40.0
Delta time in closed arm before/after self-admin0.50.53.7-0.2-0.1-0.50.20.50.20.10.0-0.41.8-0.40.4-0.40.4-0.40.40.01.9-1.20.7-0.5-0.6-0.60.7-0.9-0.80.0
Delta time in open arm before/after self-admin1.41.34.1-1.4-1.42.0-1.5-1.70.70.91.21.1-1.01.0-1.01.0-1.01.0-1.00.5-1.62.0-0.90.60.40.5-0.80.91.00.0
Diff in mean of infusions in LGA sessions0.40.43.00.70.6-0.90.40.40.20.2-0.00.1-1.70.1-0.10.1-0.20.2-0.20.5-1.4-0.3-1.00.81.11.10.3-0.0-0.30.0
Delay discount exponential model param0.20.21.20.00.0-0.30.10.30.30.20.1-0.20.9-0.30.3-0.30.3-0.30.30.11.1-0.60.4-0.2-0.3-0.30.6-0.6-0.60.0
Extinction: sum of active levers before priming0.60.61.40.40.5-0.00.60.4-0.9-1.0-0.5-0.80.9-0.90.9-0.90.9-0.90.9-1.10.70.41.2-1.0-1.1-1.1-0.70.50.60.0
Active lever presses in extinction session 60.60.61.4-0.2-0.10.40.00.1-0.4-0.5-0.6-0.61.0-1.01.0-1.01.0-1.01.0-0.70.80.71.1-1.0-1.2-1.1-0.70.50.70.0
Bone: final force0.81.44.72.01.9-2.21.71.8-0.9-0.9-0.7-1.1-2.1-1.11.1-1.11.1-1.11.1-0.4-1.6-0.3-0.1-0.10.40.3-0.10.60.10.0
Bone: final moment0.91.44.52.12.0-2.11.81.8-1.0-1.0-0.8-1.3-1.9-1.11.1-1.11.1-1.11.1-0.5-1.5-0.30.1-0.30.20.1-0.20.70.20.0
Food consumed during 24 hour testing period0.70.83.11.21.0-1.70.80.90.30.30.3-0.0-1.80.3-0.30.3-0.30.3-0.30.8-1.2-1.2-1.21.01.41.30.9-0.6-1.00.0
Glucose0.10.11.3-0.2-0.20.1-0.00.00.10.1-0.1-0.11.2-0.00.00.0-0.00.0-0.0-0.21.1-0.50.4-0.3-0.4-0.40.2-0.5-0.30.0
Heart weight0.20.21.3-0.2-0.00.20.10.1-0.3-0.4-0.3-0.31.1-0.40.4-0.20.2-0.20.2-0.51.1-0.20.8-0.6-0.8-0.7-0.1-0.00.10.0
Delay discount hyperbolic model param0.20.21.30.20.2-0.40.30.5-0.1-0.2-0.2-0.51.0-0.50.5-0.50.5-0.50.5-0.21.1-0.50.6-0.5-0.5-0.50.3-0.4-0.40.0
Intermittent access intake day 1-15 change0.30.31.30.70.6-0.80.50.6-0.3-0.4-0.3-0.4-1.1-0.70.7-0.70.7-0.70.7-0.0-1.0-0.2-0.20.00.20.2-0.00.40.10.0
Intermittent access intake escalation0.40.40.90.90.8-0.90.70.8-0.5-0.5-0.5-0.6-0.5-0.90.9-0.90.9-0.90.9-0.2-0.4-0.50.1-0.2-0.1-0.10.10.1-0.10.0
Intermittent access intake escalation 21.51.54.22.01.8-1.81.71.6-1.3-1.3-1.3-1.2-1.2-1.51.5-1.51.5-1.51.5-0.7-0.8-0.80.2-0.4-0.0-0.1-0.20.30.00.0
Intermitt. access day 1 inactive lever presses2.83.05.31.11.10.21.00.7-2.0-2.0-2.0-1.3-0.8-2.22.2-2.22.2-2.22.2-2.0-1.32.01.4-1.6-1.6-1.6-2.22.32.20.0
Intermitt. access day 15 inactive lever presses2.22.44.71.71.7-1.11.61.4-1.9-1.9-1.9-1.5-0.3-2.22.2-2.22.2-2.22.2-1.6-0.30.21.3-1.3-1.2-1.2-1.11.10.90.0
Intermitt. access escalation Index0.20.20.7-0.4-0.50.6-0.5-0.50.30.30.30.4-0.60.4-0.40.4-0.40.4-0.40.2-0.80.6-0.40.20.20.2-0.40.40.40.0
Intermittent access day 1 total infusions1.11.33.11.61.5-0.71.51.0-1.8-1.7-1.8-1.1-0.1-1.11.1-1.11.1-1.11.1-1.5-0.10.31.0-0.9-0.8-0.8-1.00.70.70.0
Intermittent access day 15 total infusions1.21.43.11.51.4-0.61.41.0-1.8-1.7-1.7-1.1-0.2-1.31.3-1.31.3-1.31.3-1.5-0.30.41.0-1.0-0.9-0.9-1.10.90.80.0
Intermittent access terminal intake (last 3 days)1.11.23.11.71.6-0.91.61.1-1.8-1.7-1.8-1.0-0.4-1.11.1-1.11.1-1.11.1-1.4-0.40.00.8-0.8-0.6-0.7-0.90.70.60.0
Intermittent access total infusions1.71.94.51.81.8-0.81.81.2-2.1-2.0-2.1-1.30.2-1.51.5-1.51.5-1.51.5-1.90.20.21.3-1.3-1.2-1.2-1.10.80.80.0
Intermittent access day 1 locomotion0.90.91.50.70.8-0.10.70.6-1.2-1.2-1.2-0.8-0.2-1.21.2-1.21.2-1.21.2-1.2-0.40.90.9-1.0-0.9-0.9-1.01.01.00.0
Intermittent access day 15 total locomotion1.51.63.11.11.1-0.21.10.8-1.8-1.7-1.8-1.10.1-1.51.5-1.51.5-1.51.5-1.7-0.10.91.3-1.3-1.3-1.3-1.31.11.20.0
Intermittent access total locomotion1.11.23.01.71.6-1.01.61.2-1.7-1.7-1.7-1.1-0.2-1.11.1-1.11.1-1.11.1-1.4-0.1-0.00.9-0.8-0.7-0.7-0.80.50.50.0
Intermittent access standard deviation1.92.06.52.52.3-2.52.02.0-1.4-1.4-1.3-1.2-2.0-1.51.5-1.51.5-1.51.5-0.6-1.5-1.1-0.2-0.00.50.40.00.4-0.20.0
Left kidney weight0.82.24.01.61.7-1.11.91.5-1.9-1.9-1.8-1.71.5-1.31.3-1.31.3-1.31.3-2.01.6-0.12.0-1.7-1.7-1.7-0.70.20.50.0
Right kidney weight0.10.31.10.60.6-0.30.80.5-0.9-0.8-0.9-0.60.7-0.40.4-0.30.3-0.30.3-1.10.7-0.10.8-0.7-0.7-0.7-0.40.10.30.0
Cocaine induced anxiety0.10.10.60.60.5-0.80.40.5-0.0-0.1-0.1-0.2-0.2-0.10.1-0.10.1-0.10.10.10.0-0.5-0.20.20.40.30.5-0.4-0.50.0
Post-drug Anxiety1.01.12.01.41.3-0.81.21.0-1.3-1.3-1.3-1.0-0.7-1.41.4-1.41.4-1.41.4-1.1-0.70.50.6-0.7-0.6-0.6-0.70.90.70.0
Baseline Anxiety1.21.35.5-0.9-0.81.7-0.8-0.8-0.4-0.4-0.3-0.2-0.2-1.01.0-1.01.0-1.01.0-0.7-1.02.30.8-1.1-1.3-1.3-1.81.92.00.0
Tail length0.51.48.91.91.6-1.31.41.1-1.0-0.9-0.8-0.7-3.0-0.50.5-0.60.6-0.60.6-0.4-2.90.6-0.70.20.70.6-0.81.20.80.0
Length with tail1.55.411.23.33.1-1.83.02.3-3.1-2.9-2.8-2.4-2.8-2.12.1-2.22.2-2.22.2-2.4-2.81.51.0-1.5-1.0-1.0-2.42.52.20.0
Length without tail1.43.15.82.01.8-0.82.01.5-2.4-2.4-2.3-2.0-0.3-1.81.8-1.81.9-1.91.9-2.3-0.51.31.7-1.8-1.7-1.7-1.91.61.70.0
Times rat made contact with spout0.10.21.0-0.5-0.50.6-0.3-0.4-0.0-0.10.0-0.01.0-0.20.2-0.20.2-0.20.2-0.30.80.30.5-0.4-0.6-0.60.1-0.10.10.0
Lifetime Intake1.31.43.31.51.4-0.61.51.0-1.8-1.8-1.8-1.10.3-1.31.3-1.31.3-1.31.3-1.60.20.31.2-1.2-1.1-1.1-1.10.70.80.0
Liver weight, left1.01.63.90.50.70.00.90.7-1.3-1.3-1.3-1.31.7-1.21.2-1.21.2-1.21.2-1.71.60.42.0-1.8-1.9-1.9-1.10.60.90.0
Liver weight, right3.45.68.92.52.6-1.32.62.2-3.0-2.9-3.0-2.7-0.6-2.72.7-2.72.7-2.72.7-2.8-0.71.42.4-2.5-2.2-2.3-2.42.32.30.0
Locomotor activity3.35.38.5-2.5-2.51.5-2.4-2.22.72.72.62.50.92.9-2.92.9-2.92.9-2.92.31.0-1.3-2.12.32.02.11.8-2.1-1.90.0
Locomotor testing distance2.23.78.8-3.0-2.82.3-2.8-2.52.42.42.32.21.12.1-2.12.1-2.12.1-2.11.80.8-0.3-1.41.51.11.21.0-1.2-0.90.0
Locomotor testing rearing1.11.63.4-1.7-1.71.4-1.8-1.61.61.61.61.6-0.81.3-1.31.3-1.31.3-1.31.3-1.00.5-1.51.31.21.20.3-0.1-0.20.0
Locomotion in novel chamber0.30.42.40.60.7-0.20.40.2-0.8-0.7-0.6-0.2-1.5-0.30.3-0.30.4-0.40.4-0.5-1.50.6-0.20.00.20.2-0.71.00.70.0
Locomotion in novel chamber post-restriction0.40.51.0-0.8-0.70.3-0.7-0.60.80.80.80.80.11.0-1.01.0-0.80.8-0.80.70.2-0.6-0.60.80.70.70.6-0.6-0.60.0
Fecal boli incidents, locomotor time 12.32.54.71.81.7-1.41.91.9-1.5-1.6-1.7-2.00.6-2.22.2-2.11.8-1.81.8-1.50.7-0.21.8-1.8-1.7-1.8-0.70.70.70.0
Change in fecal boli incidents, locomotor task1.00.91.8-1.2-1.00.9-1.1-1.11.01.00.71.10.11.3-1.31.3-1.31.3-1.30.90.00.0-0.80.90.80.80.4-0.5-0.40.0
Time >=10cm from walls, locomotor time 10.70.73.1-1.6-1.51.8-1.5-1.30.60.60.20.7-0.20.1-0.10.2-0.40.4-0.40.3-0.71.6-0.1-0.1-0.3-0.3-0.90.91.00.0
Bouts of movement, locomotor time 10.50.51.71.11.1-0.31.10.6-1.2-1.1-1.3-0.70.0-0.40.4-0.30.2-0.20.2-1.1-0.00.10.8-0.7-0.6-0.6-0.90.60.70.0
Total resting periods, locomotor time 10.80.92.91.51.5-0.61.50.9-1.6-1.5-1.7-1.0-0.1-0.60.6-0.60.5-0.50.5-1.4-0.10.10.9-0.9-0.8-0.8-1.10.70.80.0
Rest time, locomotor task time 11.71.95.72.42.2-2.32.12.1-1.3-1.4-1.4-1.5-1.2-1.61.6-1.51.5-1.51.5-0.9-0.8-0.80.6-0.7-0.3-0.4-0.10.50.10.0
Distance moved, locomotor task time 10.70.82.5-1.5-1.41.6-1.3-1.40.70.71.01.00.61.1-1.11.1-0.70.7-0.70.40.20.8-0.40.50.20.3-0.1-0.10.10.0
Vertical activity count, locomotor time 10.91.02.0-1.1-1.21.0-1.2-1.21.01.11.11.2-0.11.4-1.41.3-1.21.2-1.20.9-0.20.3-1.01.00.90.90.3-0.5-0.40.0
Time >=10cm from walls, locomotor time 20.20.20.7-0.5-0.50.1-0.6-0.30.60.60.40.4-0.80.2-0.20.3-0.30.3-0.30.7-0.80.0-0.70.50.50.50.20.0-0.10.0
Bouts of movement, locomotor time 20.90.95.11.51.4-2.31.31.5-0.0-0.00.2-0.5-0.5-0.10.1-0.2-0.00.0-0.00.40.2-2.0-0.40.50.90.81.4-1.2-1.50.0
Total resting periods, locomotor time 21.21.37.11.81.7-2.71.61.9-0.2-0.2-0.0-0.8-0.3-0.50.5-0.50.3-0.30.30.30.5-2.3-0.20.30.70.61.5-1.3-1.60.0
Rest time, locomotor task time 23.43.97.72.62.5-2.62.52.8-1.8-1.9-2.1-2.4-0.1-2.72.7-2.62.5-2.52.5-1.60.3-0.61.7-1.7-1.4-1.5-0.40.60.30.0
Distance moved, locomotor task time 20.30.31.0-0.2-0.30.2-0.4-0.40.40.50.50.6-1.00.7-0.70.7-0.50.5-0.50.7-1.00.2-0.90.80.90.90.1-0.0-0.10.0
Vertical activity count, locomotor time 20.40.51.1-0.2-0.30.1-0.4-0.50.60.60.80.7-0.71.0-1.00.9-0.70.7-0.70.8-0.7-0.2-1.10.91.01.00.3-0.4-0.40.0
Light reinforcement 12.13.914.23.73.3-3.83.23.2-1.7-1.8-1.7-2.2-2.3-1.91.9-1.91.9-1.91.9-0.9-1.5-1.40.2-0.40.30.20.00.3-0.20.0
Light reinforcement 23.24.312.73.63.3-3.33.33.1-2.3-2.3-2.4-2.5-1.1-2.22.2-2.12.2-2.22.2-1.6-0.5-1.11.2-1.2-0.7-0.8-0.50.50.20.0
Bone: marrow area1.02.211.82.22.0-3.41.82.10.20.10.2-0.5-1.7-0.00.0-0.10.1-0.10.11.0-0.6-2.8-1.11.21.81.72.1-1.4-2.10.0
Bone: maximum diameter1.01.99.62.32.1-2.91.82.0-0.4-0.3-0.2-0.7-3.1-0.50.5-0.50.5-0.50.50.5-2.4-1.1-1.10.91.51.40.8-0.0-0.70.0
Bone: maximum force0.71.24.51.81.8-2.11.51.7-0.8-0.8-0.5-0.9-2.1-0.90.9-0.90.9-0.90.9-0.2-1.7-0.4-0.20.00.50.40.00.60.00.0
Bone: maximum moment0.61.13.61.71.7-1.91.51.6-0.9-0.9-0.6-1.0-1.9-1.01.0-1.01.0-1.01.0-0.4-1.5-0.2-0.0-0.10.30.2-0.10.60.10.0
Mean time between licks in bursts2.43.37.12.12.2-2.42.42.7-1.8-1.8-1.9-2.50.5-2.22.2-2.22.2-2.22.2-1.80.9-0.71.9-1.8-1.6-1.6-0.60.50.40.0
Mean num. licks in bursts0.70.82.9-1.2-1.01.6-0.9-0.8-0.2-0.2-0.10.01.7-0.50.5-0.50.5-0.50.5-0.51.11.11.2-1.1-1.5-1.4-0.80.60.90.0
Cd content in liver2.22.44.71.31.6-1.21.71.7-1.7-1.8-1.8-1.81.5-1.51.5-1.61.6-1.61.6-1.81.7-0.42.2-1.8-1.8-1.8-0.80.40.50.0
Co content in liver0.30.41.4-0.3-0.10.20.00.1-0.4-0.5-0.5-0.51.2-0.60.6-0.60.6-0.60.6-0.61.10.21.1-0.9-1.0-1.0-0.40.20.40.0
Cu content in liver0.20.21.7-0.2-0.30.6-0.3-0.40.10.20.00.2-1.10.1-0.10.00.0-0.00.00.1-1.31.1-0.40.10.20.2-0.70.70.70.0
Fe content in liver0.10.10.50.50.3-0.70.30.40.20.1-0.0-0.1-0.7-0.10.1-0.10.1-0.10.10.4-0.5-0.2-0.40.30.50.50.4-0.2-0.40.0
K content in liver1.51.54.20.1-0.2-0.3-0.4-0.51.01.01.21.1-1.91.4-1.41.3-1.21.2-1.21.2-1.6-0.3-2.01.82.02.00.9-0.7-0.90.0
Mg content in liver2.62.75.3-0.7-0.90.3-1.1-1.21.61.71.81.7-1.22.1-2.12.1-2.02.0-2.01.7-1.0-0.5-2.32.22.32.31.3-1.2-1.30.0
Mn content in liver0.30.40.80.20.20.20.30.2-0.6-0.6-0.6-0.50.2-0.70.7-0.70.7-0.70.7-0.70.00.70.8-0.8-0.9-0.9-0.70.70.80.0
Na content in liver4.04.211.0-0.4-0.9-0.4-1.2-0.92.22.32.31.9-2.81.9-1.91.9-1.91.9-1.92.7-2.4-1.0-3.32.93.23.21.9-1.3-1.80.0
Rb content in liver1.21.52.5-1.6-1.51.1-1.5-1.41.41.41.31.50.61.6-1.61.5-1.51.5-1.51.10.6-0.6-1.01.21.01.00.9-1.0-0.90.0
Se content in liver0.20.20.70.90.7-0.80.80.7-0.5-0.5-0.5-0.6-0.3-0.50.5-0.50.5-0.50.5-0.4-0.1-0.20.2-0.2-0.1-0.10.10.0-0.10.0
Sr content in liver1.51.42.0-1.1-1.20.7-1.2-1.21.41.41.41.4-0.11.4-1.41.4-1.41.4-1.41.4-0.0-0.5-1.31.31.21.21.0-1.0-0.90.0
Zn content in liver0.40.41.91.31.2-1.41.00.9-0.1-0.1-0.1-0.2-1.00.2-0.20.2-0.10.1-0.10.2-0.6-0.7-0.70.60.90.80.3-0.4-0.60.0
Bone: minimum diameter2.13.917.33.53.4-4.23.23.5-1.5-1.5-1.4-2.2-2.2-1.71.7-1.81.8-1.81.8-0.7-1.2-1.70.3-0.40.40.20.50.1-0.60.0
Time in familiar zone, hab. session 10.30.30.6-0.3-0.40.5-0.4-0.60.40.40.40.6-0.30.7-0.70.8-0.80.8-0.80.5-0.40.1-0.70.60.60.6-0.0-0.2-0.10.0
Time in novel zone, hab. session 10.40.41.00.10.2-0.20.30.5-0.4-0.5-0.5-0.60.7-0.80.8-0.90.9-0.90.9-0.70.60.11.0-0.9-0.9-0.9-0.20.30.30.0
Total zone transitions, hab. session 11.42.04.9-1.3-1.41.5-1.7-1.81.21.31.51.8-1.91.2-1.21.3-1.31.3-1.31.5-2.21.1-1.91.61.61.60.10.40.20.0
Total locomotion distance, hab. session 18.411.920.34.44.5-3.14.44.0-4.3-4.2-4.1-4.0-2.0-3.83.8-3.83.8-3.83.8-3.7-1.81.53.0-3.2-2.6-2.7-3.03.22.80.0
Locomotion velocity, hab. session 19.012.821.44.64.6-3.14.54.1-4.4-4.4-4.3-4.1-2.1-3.93.9-3.83.8-3.83.8-3.9-2.01.83.0-3.3-2.6-2.7-3.33.43.10.0
Time in familiar zone, hab. session 20.10.10.70.70.6-0.90.60.7-0.2-0.2-0.1-0.3-0.1-0.20.2-0.10.1-0.10.1-0.10.1-0.70.00.00.20.10.3-0.3-0.40.0
Time in novel zone, hab. session 20.10.10.6-0.7-0.70.7-0.7-0.60.40.40.30.40.40.1-0.10.1-0.10.1-0.10.30.30.40.00.0-0.1-0.10.00.00.10.0
Total zone transitions, hab. session 22.02.65.4-1.2-1.41.3-1.7-1.81.61.61.72.0-1.91.7-1.71.7-1.71.7-1.71.8-2.10.5-2.32.02.12.10.6-0.2-0.40.0
Total locomotion distance, hab. session 26.78.819.04.44.3-3.54.23.9-3.6-3.6-3.5-3.5-2.3-3.13.1-3.13.1-3.13.1-3.0-1.90.62.1-2.3-1.7-1.8-2.12.41.90.0
Locomotion velocity, hab. session 26.99.219.34.44.4-3.34.23.8-3.8-3.7-3.6-3.5-2.4-3.13.1-3.13.1-3.13.1-3.1-2.11.02.2-2.4-1.8-1.9-2.32.62.20.0
Novel to familiar place preference ratio0.90.91.7-0.5-0.6-0.1-0.7-0.51.21.21.10.9-0.21.0-1.01.0-1.01.0-1.01.3-0.0-0.7-1.21.21.31.21.2-1.1-1.20.0
Novelty place preference0.91.01.7-0.6-0.70.0-0.7-0.51.21.21.11.00.11.0-1.01.1-1.11.1-1.11.30.2-0.7-1.21.21.21.11.3-1.2-1.30.0
Time in novel zone, NPP test1.21.32.0-1.1-1.10.5-1.1-0.91.41.41.31.20.31.2-1.21.3-1.31.3-1.31.40.4-0.7-1.21.21.11.11.3-1.3-1.30.0
Total zone transitions, NPP test0.20.31.8-0.3-0.30.9-0.5-0.70.00.10.20.4-1.10.2-0.20.2-0.20.2-0.20.1-1.31.0-0.40.20.20.3-0.70.90.80.0
Total locomotion distance, NPP test12.416.927.95.15.3-3.85.34.9-5.0-5.0-4.9-5.0-1.2-4.64.6-4.64.6-4.64.6-4.5-1.01.04.0-4.1-3.4-3.6-3.33.33.00.0
Locomotion velocity, NPP test12.818.231.65.55.6-4.25.65.2-5.2-5.2-5.1-5.2-1.5-4.74.7-4.74.7-4.74.7-4.6-1.20.94.0-4.1-3.4-3.5-3.23.33.00.0
Intraocular pressure0.60.82.5-1.6-1.41.1-1.5-1.11.31.31.31.10.20.7-0.70.7-0.80.8-0.81.20.00.1-0.70.70.50.50.4-0.3-0.30.0
Delta distance traveled before/after self-admin1.01.15.01.41.2-2.01.11.10.10.20.1-0.1-0.60.6-0.60.6-0.60.6-0.60.60.2-2.2-0.91.01.31.31.3-1.4-1.60.0
Delta ambulatory time before/after self-admin0.60.73.51.41.2-1.71.21.1-0.3-0.3-0.2-0.50.00.1-0.10.1-0.10.1-0.10.10.6-1.9-0.20.40.60.50.9-1.1-1.20.0
Parametrial fat weight1.32.59.5-1.1-0.72.6-0.6-1.2-1.3-1.3-1.1-0.31.4-0.60.6-0.70.8-0.80.8-2.00.43.11.9-1.9-2.3-2.2-2.52.12.60.0
Pavlov. Cond. lever latency1.31.65.2-0.6-0.6-0.5-0.4-0.11.31.21.10.71.71.1-1.11.0-1.01.0-1.01.22.2-2.3-0.60.90.80.82.0-2.3-2.20.0
Pavlov. Cond. magazine entry latency3.95.011.61.61.6-0.11.51.2-2.5-2.4-2.4-1.9-2.1-2.42.4-2.42.4-2.42.4-2.4-2.73.01.6-2.1-1.8-1.8-3.13.43.20.0
Pavlov. Cond. change in total contacts7.37.811.12.82.8-1.52.82.5-3.3-3.3-3.2-3.0-1.9-3.33.3-3.23.2-3.23.2-3.0-2.22.22.4-2.7-2.3-2.4-3.03.33.10.0
Pavlov. Cond. index score2.73.49.31.11.10.31.00.7-2.0-2.0-1.9-1.4-2.0-1.81.8-1.81.8-1.81.8-1.9-2.52.81.2-1.6-1.5-1.5-2.83.02.90.0
Pavlov. Cond. latency score2.33.08.80.90.90.50.80.4-1.8-1.7-1.6-1.1-2.1-1.61.6-1.61.6-1.61.6-1.7-2.72.91.0-1.4-1.2-1.2-2.63.02.80.0
Pavlov. Cond. lever contacts1.51.85.60.80.80.40.60.3-1.5-1.4-1.3-0.8-1.7-1.21.2-1.21.2-1.21.2-1.3-2.22.20.7-1.0-0.9-0.9-2.12.42.20.0
Pavlov. Cond. magazine entry number2.02.57.7-0.5-0.6-0.7-0.5-0.21.61.51.51.01.61.5-1.51.5-1.51.5-1.51.62.2-2.8-1.01.41.31.32.5-2.8-2.70.0
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.0-0.0-0.2-0.1-0.00.30.30.30.2-0.20.2-0.20.3-0.30.3-0.30.4-0.1-0.4-0.40.40.40.40.3-0.3-0.40.0
Pavlov. Cond. lever-magazine prob. diff.3.24.09.71.21.30.21.20.8-2.3-2.2-2.1-1.6-1.8-2.12.1-2.02.0-2.02.0-2.2-2.32.91.5-1.9-1.7-1.7-2.93.13.00.0
Pavlov. Cond. response bias3.44.27.71.71.8-0.51.71.4-2.5-2.4-2.4-2.0-1.4-2.22.2-2.22.2-2.22.2-2.4-1.72.21.8-2.0-1.8-1.8-2.62.82.60.0
Pavlov. Cond. lever latency1.31.75.71.61.6-1.91.91.8-1.1-1.1-1.1-1.61.9-0.80.8-0.70.7-0.70.7-1.02.4-1.81.4-1.1-1.0-1.10.4-1.0-0.80.0
Pavlov. Cond. magazine entry latency0.80.93.9-1.7-1.62.0-1.7-1.60.60.60.71.1-0.50.4-0.40.3-0.30.3-0.30.2-1.01.7-0.40.20.00.1-0.61.00.90.0
Pavlov. Cond. change in total contacts1.01.47.4-1.2-1.21.7-1.5-1.50.50.60.71.1-2.10.3-0.30.2-0.20.2-0.20.4-2.72.3-1.00.60.50.6-1.01.61.40.0
Pavlov. Cond. index score1.52.05.6-2.0-1.92.3-2.2-2.11.11.11.11.7-1.70.8-0.80.7-0.70.7-0.70.9-2.42.2-1.31.00.80.9-0.61.21.00.0
Pavlov. Cond. latency score1.41.75.2-1.8-1.72.1-2.0-1.91.01.11.11.6-1.70.8-0.80.7-0.70.7-0.70.9-2.32.0-1.20.90.80.9-0.51.10.90.0
Pavlov. Cond. lever contacts2.23.06.6-2.2-2.22.3-2.5-2.41.71.71.72.2-2.11.4-1.41.4-1.41.4-1.41.6-2.61.7-2.01.71.61.70.00.70.40.0
Pavlov. Cond. magazine entry number1.21.54.62.12.0-2.12.22.0-1.2-1.3-1.3-1.60.5-1.01.0-0.90.9-0.90.9-0.91.0-1.31.0-0.9-0.7-0.70.0-0.4-0.30.0
Pavlov. Cond. intertrial magazine entries0.10.10.60.40.3-0.30.20.20.00.10.0-0.0-0.80.1-0.10.1-0.10.1-0.10.3-0.7-0.1-0.50.30.40.4-0.10.1-0.00.0
Pavlov. Cond. lever-magazine prob. diff.1.62.05.3-2.1-1.92.3-2.3-2.21.21.21.21.7-1.60.9-0.90.8-0.80.8-0.80.9-2.22.0-1.31.00.90.9-0.51.10.90.0
Pavlov. Cond. response bias1.82.56.5-2.2-2.12.4-2.4-2.31.41.41.42.0-2.01.1-1.11.0-1.01.0-1.01.2-2.62.1-1.61.31.21.2-0.31.00.80.0
Time in closed arm before self-admin1.21.34.51.51.4-0.91.11.0-1.3-1.3-1.2-0.9-2.1-1.11.1-1.11.2-1.21.2-0.9-2.10.80.1-0.4-0.0-0.1-1.11.41.10.0
Time in closed arm after self-admin1.81.83.71.81.8-1.91.71.9-1.4-1.5-1.3-1.5-0.5-1.81.8-1.81.8-1.81.8-1.0-0.2-0.60.9-0.9-0.6-0.7-0.30.50.20.0
Time in open arm before self-admin0.50.63.60.30.3-0.40.60.6-0.4-0.5-0.9-0.61.8-0.40.4-0.40.4-0.40.4-0.51.9-1.01.0-0.7-0.8-0.80.2-0.7-0.50.0
Time in open arm after self-admin1.11.25.6-1.7-1.62.4-1.5-1.90.60.70.51.10.61.2-1.21.2-1.21.2-1.20.20.01.6-0.20.1-0.2-0.1-0.80.50.90.0
Bone: periosteal estimation1.32.713.12.92.8-3.62.42.7-0.7-0.8-0.6-1.2-3.1-1.01.0-1.11.1-1.11.10.2-2.2-1.5-0.80.51.31.20.80.0-0.80.0
Bone: periosteal perimeter1.22.17.32.52.4-2.72.22.3-1.1-1.1-1.1-1.4-2.4-1.31.3-1.31.3-1.31.3-0.4-1.8-0.5-0.0-0.20.40.3-0.00.60.00.0
Bone: post-yield work0.81.13.90.50.4-1.10.10.20.70.70.80.7-2.00.7-0.70.7-0.70.7-0.71.3-1.5-1.0-1.61.51.81.81.1-0.6-1.10.0
Progressive ratio test 1 active lever presses0.20.20.40.50.5-0.70.50.6-0.3-0.4-0.3-0.40.3-0.70.7-0.70.7-0.70.7-0.30.4-0.50.4-0.3-0.3-0.30.2-0.2-0.20.0
Progressive ratio test 1 breakpoint0.10.20.40.40.4-0.60.40.6-0.2-0.3-0.2-0.40.1-0.60.6-0.60.6-0.60.6-0.20.1-0.40.2-0.2-0.2-0.20.1-0.1-0.20.0
Progressive ratio test 1 inactive lever presses3.33.66.01.11.10.41.10.7-2.3-2.3-2.3-1.5-0.2-2.32.3-2.32.3-2.32.3-2.3-0.72.11.8-2.0-2.0-2.0-2.52.32.30.0
Progressive ratio test 2 active lever presses1.31.43.21.81.7-1.21.71.3-1.7-1.7-1.8-1.2-0.1-1.31.3-1.31.3-1.31.3-1.40.1-0.30.9-0.9-0.7-0.7-0.70.50.40.0
Progressive ratio test 2 breakpoint1.31.43.61.91.8-1.31.81.4-1.8-1.7-1.8-1.2-0.4-1.31.3-1.31.3-1.31.3-1.4-0.2-0.30.8-0.8-0.6-0.6-0.70.50.40.0
Progressive ratio test 2 inactive lever presses2.73.17.12.12.1-0.72.01.3-2.7-2.6-2.7-1.6-0.5-1.91.9-1.91.9-1.91.9-2.3-0.71.01.5-1.5-1.3-1.4-1.91.61.60.0
Incentive Sensitization - Responses0.60.61.81.31.3-0.71.20.8-1.3-1.3-1.3-0.7-0.1-0.60.6-0.60.6-0.60.6-1.1-0.0-0.10.6-0.5-0.4-0.4-0.60.30.30.0
Incentive Sensitization - Breakpoint0.70.72.11.41.4-0.81.30.9-1.4-1.4-1.4-0.8-0.2-0.70.7-0.70.7-0.70.7-1.2-0.1-0.10.6-0.5-0.4-0.4-0.70.40.40.0
Sum of active levers in priming session hrs 5-60.10.10.40.20.3-0.10.40.3-0.5-0.4-0.4-0.40.6-0.20.2-0.20.2-0.20.2-0.50.6-0.10.5-0.4-0.5-0.5-0.2-0.00.10.0
Progressive ratio0.10.10.20.20.3-0.20.30.2-0.2-0.20.1-0.10.3-0.30.3-0.30.4-0.40.4-0.20.4-0.20.3-0.1-0.1-0.10.4-0.1-0.20.0
Food seeking constrained by brief footshock0.20.31.4-0.0-0.20.2-0.20.0-0.2-0.2-0.5-0.2-1.0-0.40.4-0.40.6-0.60.60.2-1.20.9-0.0-0.3-0.2-0.2-0.90.90.90.0
Seeking ratio, punishment vs. effort0.20.31.40.30.10.00.10.2-0.3-0.2-0.7-0.3-1.0-0.20.2-0.20.3-0.30.3-0.0-1.20.7-0.1-0.2-0.1-0.2-1.10.80.80.0
Retroperitoneal fat weight1.75.517.6-1.2-0.83.3-0.5-1.2-2.0-2.0-2.1-0.92.0-1.31.3-1.41.5-1.51.5-3.00.74.23.0-2.9-3.5-3.4-3.73.03.70.0
Reaction time number correct0.81.15.0-1.1-1.00.4-0.8-0.71.11.01.10.72.10.8-0.80.9-0.90.9-0.90.92.2-1.4-0.00.40.10.11.3-1.6-1.30.0
Reaction time mean minus median0.30.43.10.20.1-0.1-0.2-0.10.20.30.40.5-1.80.3-0.30.4-0.40.4-0.40.4-1.70.5-1.00.81.00.90.00.40.10.0
Reaction time mean minus median AUC0.10.10.90.00.10.0-0.2-0.20.10.20.20.3-0.90.3-0.30.3-0.30.3-0.30.2-0.90.4-0.50.40.50.5-0.00.20.10.0
Reaction time num false alarms3.64.916.03.83.6-4.03.63.6-2.2-2.3-2.2-2.7-0.1-2.22.2-2.22.1-2.12.1-1.40.8-2.21.5-1.3-0.7-0.90.5-0.4-0.80.0
Reaction time num false alarms AUC1.82.510.92.82.6-3.32.62.6-1.3-1.3-1.3-1.70.2-1.11.1-1.11.1-1.11.1-0.61.1-2.60.8-0.4-0.1-0.11.2-1.1-1.40.0
Reaction time trials correct on left0.81.15.0-1.1-1.00.4-0.8-0.71.11.01.10.72.10.8-0.80.9-0.90.9-0.90.92.2-1.4-0.00.40.10.11.3-1.6-1.30.0
Reaction time trials on left0.81.25.1-1.1-1.00.4-0.9-0.71.21.11.10.72.10.8-0.80.9-0.90.9-0.90.92.3-1.5-0.10.40.10.21.4-1.6-1.40.0
Reaction time mean0.00.10.5-0.0-0.00.4-0.1-0.2-0.2-0.2-0.20.1-0.20.0-0.00.0-0.10.1-0.1-0.4-0.30.70.1-0.1-0.1-0.1-0.40.30.40.0
Reaction time mean AUC0.10.11.1-0.2-0.20.6-0.3-0.5-0.1-0.1-0.10.2-0.30.1-0.10.1-0.10.1-0.1-0.4-0.51.0-0.0-0.1-0.1-0.1-0.50.50.60.0
Median of all reaction times0.10.10.50.10.10.30.1-0.1-0.4-0.4-0.5-0.20.3-0.20.2-0.10.1-0.10.1-0.70.10.60.5-0.4-0.5-0.5-0.50.30.50.0
Reaction time omissions0.20.21.2-0.3-0.3-0.2-0.4-0.10.60.60.50.40.20.2-0.20.3-0.30.3-0.30.60.4-0.6-0.30.50.40.41.1-0.7-0.80.0
Reaction time false alarm rate1.72.47.92.82.6-2.82.62.5-1.7-1.7-1.7-1.8-0.5-1.41.4-1.51.4-1.41.4-1.10.1-1.40.9-0.7-0.3-0.40.3-0.1-0.40.0
Reaction time premature initiation rate0.30.43.2-0.1-0.20.3-0.4-0.40.40.40.40.4-1.70.2-0.20.2-0.20.2-0.20.5-1.80.7-0.90.60.80.8-0.20.60.40.0
Reaction time premature initiations0.20.30.7-0.7-0.80.6-0.8-0.70.80.80.80.7-0.30.5-0.50.6-0.50.5-0.50.8-0.30.1-0.70.60.60.60.4-0.2-0.20.0
Std. dev. reaction times0.81.11.9-0.9-0.90.7-1.1-1.11.01.11.11.3-1.31.1-1.11.1-1.11.1-1.11.0-1.40.5-1.41.21.31.30.5-0.1-0.20.0
Reaction time trials completed0.81.25.1-1.1-1.00.4-0.9-0.71.21.11.10.72.10.8-0.80.9-0.90.9-0.90.92.3-1.5-0.10.40.10.21.4-1.6-1.40.0
Reaction time trials AUC0.71.05.6-0.9-0.90.4-0.7-0.51.00.90.90.52.20.6-0.60.7-0.70.7-0.70.72.4-1.40.20.2-0.1-0.11.2-1.5-1.30.0
Run reversals in cocaine runway, females0.30.31.31.11.1-1.10.90.8-0.6-0.6-0.4-0.5-0.8-0.40.4-0.40.5-0.50.5-0.3-0.5-0.5-0.10.10.30.30.10.0-0.20.0
Run reversals in cocaine runway, males1.31.25.6-1.0-0.92.3-0.7-1.3-0.8-0.7-0.50.20.80.2-0.20.2-0.20.2-0.2-1.2-0.02.40.9-1.0-1.3-1.2-2.01.41.90.0
Latency to leave start box in cocaine runway1.92.07.72.72.3-2.82.02.2-0.8-0.8-1.1-1.1-2.6-1.11.1-1.11.1-1.11.10.1-2.0-1.0-0.70.30.90.80.10.2-0.30.0
Latency to leave start box in cocaine runway, F1.21.36.02.11.8-2.41.61.8-0.5-0.5-0.8-0.9-1.9-0.80.8-0.80.9-0.90.90.1-1.3-1.2-0.50.30.80.70.4-0.1-0.60.0
Latency to leave start box in cocaine runway, M0.90.83.01.71.5-1.71.31.4-0.5-0.5-0.7-0.8-1.7-0.80.8-0.80.7-0.70.70.1-1.4-0.4-0.40.10.50.4-0.10.3-0.10.0
Std. dev. time between licks in bursts0.91.13.20.90.7-1.80.60.90.60.60.70.1-1.40.5-0.50.5-0.50.5-0.51.0-0.8-1.6-1.31.31.61.61.5-1.1-1.50.0
Total sessions with >9 infusions1.92.14.12.01.9-1.52.01.7-1.8-1.9-1.9-1.50.7-1.61.6-1.61.6-1.61.6-1.60.9-0.71.4-1.2-1.1-1.1-0.40.00.00.0
Short access day 1 total inactive lever presses3.94.47.41.81.9-0.51.81.4-2.7-2.7-2.7-1.9-0.1-2.72.7-2.72.7-2.72.7-2.5-0.41.32.0-2.1-2.0-2.0-2.22.01.90.0
Short access day 10 total inactive lever presses3.94.37.01.71.7-0.11.51.0-2.6-2.6-2.6-1.7-1.0-2.52.5-2.52.5-2.52.5-2.4-1.42.11.6-1.9-1.8-1.8-2.62.52.40.0
Short access day 1 total infusions1.31.43.41.91.7-0.91.71.2-1.8-1.8-1.8-1.1-0.5-1.11.1-1.11.1-1.11.1-1.5-0.40.10.8-0.8-0.7-0.7-1.00.70.70.0
Short access day 10 total infusions0.40.50.80.80.8-0.40.70.6-0.9-0.9-0.9-0.6-0.6-0.80.8-0.80.8-0.80.8-0.7-0.70.50.4-0.5-0.4-0.4-0.70.70.70.0
Short access total infusions0.70.81.71.21.2-0.61.10.8-1.3-1.2-1.3-0.8-0.6-1.01.0-1.01.0-1.01.0-1.1-0.60.40.5-0.6-0.5-0.5-0.90.80.70.0
Short access day 1 locomotion2.22.34.42.12.0-1.21.81.5-2.0-1.9-1.9-1.4-1.3-1.91.9-1.91.9-1.91.9-1.5-1.30.40.8-1.0-0.7-0.8-1.31.31.10.0
Short access day 10 total locomotion0.60.72.61.61.4-1.61.21.2-0.7-0.7-0.7-0.6-1.4-0.60.6-0.60.6-0.60.6-0.2-1.1-0.9-0.40.30.60.60.20.0-0.30.0
Short access total locomotion1.51.65.22.32.1-1.91.91.7-1.5-1.5-1.5-1.1-1.6-1.21.2-1.21.2-1.21.2-0.8-1.3-0.60.0-0.20.20.2-0.30.50.10.0
One hour access (0.3 mA shock)0.81.02.11.11.1-0.51.10.9-1.4-1.4-1.4-0.90.3-1.11.1-1.11.1-1.11.1-1.30.20.21.0-1.0-0.9-1.0-0.80.60.60.0
Compulsive drug intake0.30.30.8-0.1-0.10.40.00.0-0.4-0.5-0.4-0.40.7-0.70.7-0.70.7-0.70.7-0.60.50.60.8-0.8-0.9-0.9-0.50.40.60.0
One hour access (shock baseline)0.40.41.61.21.2-1.01.10.9-1.0-0.9-1.0-0.6-0.1-0.50.5-0.50.5-0.50.5-0.70.1-0.60.3-0.3-0.1-0.2-0.1-0.1-0.10.0
Social response proportion0.50.62.4-1.3-1.21.2-1.0-1.00.60.60.60.61.50.8-0.80.7-0.70.7-0.70.21.30.00.10.0-0.3-0.20.1-0.5-0.10.0
Social responses1.11.52.6-0.9-0.90.1-0.9-0.71.51.41.51.10.81.4-1.41.3-1.31.3-1.31.41.0-1.5-1.01.21.11.11.6-1.6-1.60.0
Social time2.23.06.6-0.3-0.4-1.1-0.6-0.21.91.91.91.3-0.61.7-1.71.6-1.61.6-1.62.20.1-2.5-2.12.22.42.32.6-2.2-2.50.0
Soleus weight0.92.69.50.50.50.90.50.1-1.7-1.6-1.7-1.0-1.3-1.41.4-1.41.3-1.31.3-1.7-2.03.11.1-1.5-1.5-1.5-2.62.72.70.0
Bone: stiffness0.71.03.71.71.6-1.81.41.5-0.8-0.8-0.7-1.0-1.9-1.01.0-0.90.9-0.90.9-0.4-1.6-0.2-0.1-0.10.30.3-0.10.70.20.0
Tibialis anterior weight0.20.53.3-0.4-0.31.3-0.3-0.7-0.5-0.4-0.60.0-0.2-0.10.1-0.20.2-0.20.2-0.5-0.61.80.4-0.6-0.7-0.7-1.41.21.40.0
Time to tail flick, vehicle, before self-admin0.80.81.60.20.30.30.30.2-0.9-0.9-0.9-0.70.5-1.21.2-1.21.2-1.21.2-1.10.31.01.2-1.2-1.3-1.2-0.90.91.00.0
Time to tail flick, vehicle, after self-admin0.80.83.60.70.6-1.20.40.50.40.50.30.3-1.90.6-0.60.6-0.60.6-0.60.9-1.5-0.9-1.41.21.61.50.8-0.4-0.80.0
Time to tail flick, test, before self-admin2.92.96.3-0.2-0.5-0.7-0.7-0.41.81.91.71.4-1.71.8-1.81.8-1.81.8-1.82.2-1.3-1.7-2.52.32.52.51.8-1.5-1.70.0
Time to tail flick, test, after self-admin0.00.10.3-0.4-0.30.3-0.2-0.10.10.10.2-0.00.6-0.10.1-0.10.1-0.10.1-0.00.5-0.10.3-0.2-0.3-0.3-0.1-0.00.10.0
Delta time to tail flick, vehicle, before/after SA5.04.910.7-0.8-0.9-0.4-1.2-0.82.32.41.82.0-2.32.6-2.62.6-2.62.6-2.62.8-1.9-1.4-3.23.03.33.21.9-1.6-1.90.0
Delta time to tail flick, test, before/after SA1.41.33.00.10.40.20.50.5-1.0-1.1-1.0-1.01.6-1.31.3-1.31.3-1.31.3-1.31.40.51.7-1.5-1.7-1.7-0.90.60.80.0
Tibia length1.54.39.9-0.4-0.5-0.6-0.9-0.81.92.02.12.0-1.72.4-2.42.3-2.32.3-2.32.4-1.1-2.1-2.92.93.13.12.2-2.0-2.30.0
Ambulatory time before self-admin2.42.56.10.90.90.20.70.6-1.7-1.6-1.6-1.1-1.7-1.91.9-1.91.9-1.91.9-1.5-2.12.20.9-1.3-1.1-1.1-2.22.52.30.0
Ambulatory time after self-admin2.83.17.02.62.4-1.62.11.8-2.1-2.1-2.2-1.6-2.6-1.91.9-1.91.9-1.91.9-1.5-2.40.60.4-0.8-0.3-0.4-1.61.81.40.0
Bone: tissue strength3.02.94.5-1.7-1.81.1-1.9-1.82.02.02.12.0-0.02.0-2.02.0-2.02.0-2.01.90.0-0.8-1.91.91.81.81.5-1.4-1.40.0
Total heroin consumption0.00.10.40.0-0.10.40.1-0.1-0.2-0.1-0.2-0.10.00.1-0.10.1-0.10.1-0.1-0.3-0.20.40.1-0.2-0.2-0.2-0.60.30.50.0
Bone: trabecular number1.22.010.22.52.4-3.22.32.6-0.8-0.9-0.8-1.6-0.4-1.01.0-1.01.0-1.01.0-0.40.4-2.20.4-0.30.20.10.9-0.8-1.10.0
Bone: trabecular spacing2.02.67.8-2.7-2.72.8-2.7-2.71.71.71.82.10.31.5-1.51.5-1.51.5-1.51.3-0.31.0-1.21.10.70.80.2-0.20.00.0
Bone: trabecular thickness1.51.73.71.91.9-1.41.91.7-1.7-1.6-1.7-1.6-0.7-1.31.3-1.31.3-1.31.3-1.3-0.60.31.1-1.2-0.9-1.0-1.21.11.00.0
Bone: trabecular tissue density0.50.74.6-0.0-0.20.1-0.4-0.50.50.60.40.7-2.10.6-0.60.7-0.70.7-0.70.7-2.10.4-1.41.01.21.2-0.10.30.10.0
Water consumed over 24 hours0.00.10.2-0.4-0.50.4-0.4-0.40.20.20.30.20.30.1-0.10.1-0.10.1-0.10.20.30.0-0.10.1-0.0-0.00.3-0.2-0.20.0
Number of responses in last shaping day0.10.10.60.80.7-0.60.60.4-0.5-0.5-0.5-0.3-0.1-0.20.2-0.20.2-0.20.2-0.40.0-0.30.1-0.00.10.00.0-0.1-0.20.0