Hub : Genes

Pbx2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression Pbx2 0.7 0.14 3.6e-06 0.29 0.15 0.2 0.22 2.5e-05 2.3e-03 5.3e-04 3.1e-04
2 IL gene expression Pbx2 0.47 0.15 4.5e-08 0.18 0.22 0.26 0.22 4.3e-05 4.0e-06 5.5e-07 5.9e-06
3 BLA gene expression Pbx2 0.34 0.1 0.0e+00 0.28 0.32 0.34 0.34 7.1e-15 2.9e-17 1.7e-18 2.0e-18
4 pVTA gene expression Pbx2 0.3 0.11 1.3e-14 0.13 0.17 0.17 0.16 1.1e-10 1.2e-13 1.8e-13 3.0e-13
5 PL mRNA stability Pbx2 0.03 0.02 3.3e-03 0.03 0.02 0.02 0.03 3.5e-04 1.8e-03 1.4e-03 4.9e-04
6 LHb gene expression Pbx2 0.27 0.12 4.3e-05 0.11 0.09 0.07 0.1 1.2e-03 3.1e-03 8.5e-03 2.7e-03
7 Adipose gene expression Pbx2 0.15 0.07 1.8e-08 0.04 0.06 0.05 0.04 4.2e-05 1.5e-07 6.6e-06 1.3e-05
8 PL gene expression Pbx2 0.37 0.11 0.0e+00 0.37 0.36 0.41 0.41 1.2e-42 1.6e-41 1.3e-48 1.0e-48
9 OFC gene expression Pbx2 0.42 0.16 9.4e-07 0.18 0.18 0.2 0.24 3.6e-05 4.3e-05 1.5e-05 1.7e-06
10 Brain gene expression Pbx2 0.23 0.09 0.0e+00 0.16 0.19 0.18 0.19 7.6e-15 2.4e-17 6.9e-17 4.2e-17
11 NAcc gene expression Pbx2 0.25 0.1 0.0e+00 0.23 0.24 0.25 0.25 7.4e-34 5.6e-36 2.1e-37 3.4e-37
12 IC gene expression Pbx2 0.37 0.12 4.9e-13 0.18 0.28 0.25 0.26 4.2e-08 5.6e-12 5.4e-11 2.8e-11
13 Liver gene expression Pbx2 0.08 0.04 6.7e-08 0.05 0.06 0.06 0.06 5.7e-06 1.4e-07 9.3e-08 9.5e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.01.95.0-0.6-1.1-1.52.20.4-2.01.91.41.11.1-0.31.1-1.3
Area under the delay curve0.10.20.8-0.60.10.3-0.9-0.20.4-0.50.20.1-0.1-0.8-0.10.2
BMI with tail1.96.711.42.42.72.6-1.83.41.50.3-2.6-2.9-3.03.1-2.92.9
BMI without tail1.47.411.13.33.22.8-2.52.53.0-0.0-2.7-2.8-2.82.8-2.72.8
Body weight3.816.421.83.34.14.7-4.33.53.9-2.0-4.6-4.6-4.34.1-4.34.0
Weight adjusted by age1.02.87.91.01.82.0-1.70.72.8-1.3-1.8-1.6-1.61.5-1.71.3
Bone surface0.00.10.20.0-0.10.20.10.4-0.1-0.5-0.3-0.20.10.50.0-0.4
Bone volume0.10.20.70.3-0.0-0.10.60.8-0.40.6-0.0-0.10.10.60.1-0.4
Breakpoint value in progressive ratio session0.10.20.4-0.4-0.6-0.60.3-0.4-0.5-0.20.50.50.5-0.60.5-0.3
Number of licking bursts0.20.72.6-1.2-1.0-0.4-0.2-1.0-0.6-1.60.10.30.7-0.80.6-1.2
Context. condit. distance diff. score3.94.78.7-3.0-2.7-2.12.1-2.2-2.1-1.21.82.02.3-1.72.1-2.4
Locomotion velocity, session 11.92.13.5-1.4-1.5-1.51.3-1.9-0.6-0.11.51.51.7-1.61.7-1.7
Locomotion distance, session 11.21.52.8-1.1-1.2-1.41.7-0.5-1.71.11.41.21.1-0.91.1-1.0
Locomotion velocity, session 20.70.81.6-1.3-1.0-0.70.4-1.1-0.8-0.40.90.90.8-1.20.8-0.7
Locomotion distance, session 21.01.43.6-1.9-1.4-1.11.2-0.7-1.90.21.31.00.9-1.10.8-0.7
Locomotion velocity, session 30.10.10.80.50.3-0.20.0-0.10.20.90.20.10.0-0.10.10.1
Locomotion distance, session 32.12.43.6-1.4-1.6-1.91.8-1.4-1.81.01.81.61.5-1.51.5-1.3
Stereotopy head waving bouts, day 30.91.13.20.20.71.3-1.70.21.2-1.8-1.3-1.0-0.80.5-0.80.5
Stereotopy head waving duration, day 30.81.03.30.81.01.2-1.50.01.8-1.2-1.1-0.8-0.70.5-0.70.3
Locomotion velocity, session 74.24.78.8-2.7-2.4-2.42.6-1.3-3.00.92.52.01.8-2.01.7-1.6
Locomotion distance, session 75.87.510.8-2.8-2.9-3.23.3-1.9-3.21.53.12.72.7-2.52.7-2.4
Stereotopy head waving bouts, day 70.20.20.80.30.0-0.2-0.6-0.90.6-0.00.20.40.4-0.70.5-0.4
Stereotopy head waving duration, day 70.20.20.90.70.50.4-1.0-0.30.9-0.2-0.4-0.2-0.2-0.1-0.20.2
Locomotion velocity, session 81.92.26.1-2.2-1.8-0.7-0.0-2.3-0.7-2.50.61.01.3-1.51.1-1.4
Locomotion distance, session 83.75.312.5-3.5-3.0-2.22.3-1.9-2.9-1.02.01.92.2-1.82.0-2.3
Degree of sensitization distance0.20.21.2-0.8-0.5-0.1-0.1-0.3-0.2-1.10.00.10.3-0.30.3-0.5
Degree of sensitization stereotypy0.60.61.3-0.1-0.5-0.90.3-1.2-0.20.50.91.00.9-1.11.0-0.8
Conditioned locomotion1.11.32.10.40.91.4-1.21.10.8-1.2-1.4-1.4-1.21.2-1.31.0
Cocaine response after cond. corrected0.20.41.2-1.0-0.30.30.00.9-1.1-0.7-0.4-0.6-0.30.5-0.40.0
Cocaine response after cond. not corrected0.50.82.8-0.40.21.0-1.20.50.1-1.7-1.1-1.0-0.70.7-0.80.5
Cocaine response before conditioning2.02.47.11.61.51.6-2.5-0.32.7-1.5-1.5-1.1-1.10.7-1.01.4
Saline control response3.24.49.83.12.71.8-1.62.22.41.4-1.9-1.9-2.01.9-1.82.0
Bone: connectivity density0.60.92.9-0.6-0.9-0.91.70.6-1.61.00.80.70.60.10.6-0.9
Bone: cortical apparent density1.32.14.61.51.61.4-1.02.10.61.0-1.2-1.6-1.61.7-1.51.5
Bone: cortical area0.20.30.80.10.30.6-0.90.50.2-0.7-0.6-0.6-0.50.3-0.40.7
Bone: cortical porosity1.21.33.3-0.3-0.6-1.10.3-1.70.50.41.31.21.3-1.81.4-1.3
Bone: cortical porosity1.21.43.4-0.6-0.8-1.00.2-1.80.5-0.21.11.21.3-1.81.4-1.5
Bone: cortical thickness0.50.92.71.00.90.5-0.51.7-0.11.3-0.4-0.9-0.90.7-0.81.2
Bone: cortical thickness1.51.84.01.51.51.0-0.92.00.21.3-1.0-1.4-1.51.2-1.41.8
Bone: cortical tissue density1.22.04.11.41.61.3-1.02.00.60.9-1.2-1.5-1.61.6-1.51.4
Condit. Reinf. active minus inactive responses1.61.83.7-1.3-1.2-1.51.0-1.5-0.90.71.71.51.3-1.91.4-1.0
Condit. Reinf. active-inactive response ratio0.10.10.40.10.2-0.1-0.2-0.10.20.70.40.2-0.1-0.50.00.3
Condit. Reinf. active responses1.41.83.0-1.4-1.2-1.61.3-1.2-1.41.01.71.41.2-1.71.2-0.7
Condit. Reinf. inactive responses1.52.04.3-1.1-1.3-1.72.0-0.5-2.11.61.71.31.1-1.11.2-0.6
Incentive salience index mean2.53.36.5-2.5-2.1-1.81.3-1.9-1.8-0.31.91.81.7-2.21.7-1.3
Condit. Reinf. lever presses2.43.69.7-3.1-2.5-1.71.6-1.5-2.4-1.21.61.61.7-1.71.6-1.5
Condit. Reinf. active minus inactive responses0.30.51.80.90.70.6-0.9-0.21.3-0.5-0.7-0.5-0.40.3-0.40.5
Condit. Reinf. active-inactive response ratio0.40.72.80.70.70.8-1.1-0.31.7-1.2-0.9-0.5-0.40.4-0.40.4
Condit. Reinf. active responses0.10.10.50.70.30.0-0.2-0.30.70.2-0.3-0.1-0.00.20.00.1
Condit. Reinf. inactive responses0.10.10.80.60.30.00.10.4-0.20.9-0.1-0.2-0.30.3-0.20.3
Condit. Reinf. lever presses0.71.01.6-0.2-0.7-1.21.2-1.1-0.20.91.01.11.1-0.91.2-1.1
Condit. Reinf. lever reinforcers received0.10.10.50.50.1-0.2-0.0-0.70.50.1-0.00.20.3-0.20.3-0.1
Conditioned reinforcement - actives0.00.10.50.30.1-0.20.50.10.20.70.20.10.00.10.1-0.1
Conditioned reinforcement - inactives0.00.10.30.20.2-0.30.5-0.10.50.60.30.20.1-0.40.1-0.0
Conditioned locomotion0.10.10.3-0.3-0.1-0.30.5-0.40.30.10.30.40.3-0.20.2-0.2
Patch foraging indifference point 0 sec0.92.54.92.22.01.6-1.41.61.70.9-1.2-1.5-1.71.4-1.61.4
Patch foraging indifference point AUC0.00.10.50.00.10.1-0.7-0.40.3-0.4-0.20.00.1-0.40.10.1
Delay disc. indifference point, 0s delay0.20.31.1-1.0-0.40.2-0.3-0.4-0.1-1.00.10.00.1-0.60.0-0.6
Delay disc. indifference point, 16s delay0.10.10.5-0.10.3-0.1-0.10.30.10.70.40.2-0.1-0.5-0.00.4
Delay disc. indifference point, 2s delay0.40.41.7-0.6-0.00.3-0.9-0.91.0-1.3-0.00.20.1-0.80.0-0.2
Delay disc. indifference point, 24s delay0.10.21.0-0.20.40.2-0.7-0.41.00.10.20.0-0.1-0.8-0.00.2
Delay disc. indifference point, 4s delay0.80.82.60.50.81.1-1.60.21.3-0.9-0.8-0.7-0.80.0-0.70.9
Delay disc. indifference point, 8s delay0.10.21.2-0.9-0.3-0.1-0.4-0.3-0.2-0.20.60.40.2-1.10.20.0
Indifference point function ln k0.20.71.4-1.1-0.9-0.60.2-1.2-0.5-0.70.80.80.8-1.20.7-0.5
Indifference point function log k0.20.71.4-1.1-0.9-0.60.2-1.2-0.5-0.70.80.80.8-1.20.7-0.5
Patch foraging total patch changes 0 sec0.92.55.02.22.01.5-1.41.61.71.0-1.1-1.4-1.71.3-1.61.5
Patch foraging total patch changes 12 sec1.21.63.61.91.61.2-1.21.31.30.8-1.0-1.1-1.21.1-1.11.3
Patch foraging total patch changes 18 sec0.92.25.31.91.71.2-0.62.30.41.8-0.9-1.4-1.61.7-1.51.2
Patch foraging total patch changes 24 sec0.20.64.80.70.4-0.30.70.9-0.52.20.60.2-0.20.2-0.10.1
Patch foraging total patch changes 6 sec1.11.83.81.91.71.2-1.01.61.31.2-0.9-1.0-1.41.1-1.31.2
Patch foraging time to switch 0 sec0.41.43.50.91.11.1-0.21.90.10.5-0.9-1.2-1.41.8-1.51.2
Patch foraging water rate 0 sec0.10.30.60.10.50.7-0.80.40.5-0.4-0.6-0.6-0.60.1-0.60.4
Patch foraging water rate 12 sec0.00.21.10.3-0.0-0.30.40.6-0.71.10.20.10.1-0.10.1-0.5
Patch foraging water rate 18 sec0.10.30.50.60.70.7-0.60.70.40.2-0.5-0.5-0.70.3-0.70.4
Patch foraging water rate 24 sec0.20.30.90.90.50.4-0.20.80.10.5-0.4-0.5-0.40.5-0.40.3
Patch foraging water rate 6 sec0.10.10.50.30.40.3-0.30.7-0.20.4-0.2-0.3-0.50.1-0.40.4
Seeking ratio, delayed vs. immediate footshock0.91.23.11.81.11.1-1.70.40.9-0.2-1.0-0.8-0.90.8-0.81.6
Distance traveled before self-admin0.40.82.20.40.41.0-0.71.10.1-0.9-1.0-1.2-0.91.5-1.00.7
Distance traveled after self-admin1.42.43.61.61.41.8-1.91.11.5-1.1-1.9-1.7-1.41.6-1.41.5
Extensor digitorum longus weight0.00.21.5-0.3-0.00.3-0.2-0.10.5-1.2-0.5-0.2-0.10.4-0.2-0.0
Bone: elastic displacement0.30.41.40.0-0.2-0.60.6-0.4-0.11.20.80.60.5-0.70.5-0.7
Bone: elastic work0.10.10.20.10.40.2-0.40.30.40.1-0.1-0.3-0.3-0.1-0.30.1
Bone: endosteal estimation1.84.313.70.91.42.3-2.8-0.33.0-3.7-2.6-1.8-1.41.4-1.61.1
Bone: endosteal perimeter0.51.310.5-0.7-0.21.0-1.4-0.80.9-3.2-1.2-0.6-0.20.2-0.40.1
Epididymis fat weight2.512.832.74.34.02.5-0.85.71.23.9-2.0-3.3-3.93.9-3.64.0
Delta time in closed arm before/after self-admin0.70.61.10.50.71.0-0.60.80.9-0.7-1.0-0.9-0.80.9-0.90.1
Delta time in open arm before/after self-admin0.10.10.80.50.1-0.30.4-0.20.20.90.40.40.1-0.00.2-0.0
Diff in mean of infusions in LGA sessions0.91.65.9-1.5-1.6-1.21.3-0.7-2.40.11.21.11.1-0.91.1-0.5
Delay discount exponential model param0.20.20.80.5-0.1-0.20.90.3-0.50.5-0.3-0.10.10.90.1-0.2
Extinction: sum of active levers before priming0.30.41.3-1.1-0.8-0.40.1-0.9-0.4-1.00.40.50.5-0.60.4-0.4
Active lever presses in extinction session 60.40.41.0-0.5-0.2-0.81.00.0-0.10.90.90.60.3-0.70.3-0.4
Bone: final force2.74.46.11.82.12.2-2.02.41.3-0.3-2.3-2.5-2.42.2-2.32.4
Bone: final moment2.03.34.51.71.91.9-1.62.11.3-0.2-2.0-2.1-2.01.9-2.01.9
Food consumed during 24 hour testing period0.71.32.50.10.81.4-1.31.00.6-1.6-1.4-1.3-1.21.1-1.31.1
Glucose1.93.18.8-2.4-1.9-0.90.2-2.6-0.2-3.00.71.31.6-1.61.4-2.1
Heart weight1.01.66.31.11.31.4-1.7-0.12.5-1.0-1.3-0.9-1.00.5-1.01.0
Delay discount hyperbolic model param0.20.20.90.4-0.1-0.20.90.4-0.60.6-0.2-0.10.11.00.0-0.2
Intermittent access intake day 1-15 change0.00.10.20.50.20.3-0.50.0-0.3-0.1-0.3-0.2-0.10.3-0.1-0.0
Intermittent access intake escalation0.00.21.01.00.50.3-0.50.4-0.10.7-0.2-0.2-0.20.2-0.10.3
Intermittent access intake escalation 20.00.10.20.0-0.2-0.1-0.2-0.5-0.3-0.20.10.20.3-0.30.4-0.4
Intermitt. access day 1 inactive lever presses0.00.53.9-0.5-0.20.7-0.6-0.40.3-2.0-0.9-0.6-0.10.3-0.2-0.5
Intermitt. access day 15 inactive lever presses0.10.41.10.50.60.7-0.60.31.0-0.5-0.8-0.7-0.60.6-0.60.6
Intermitt. access escalation Index0.41.13.7-1.5-1.5-1.00.8-0.5-1.9-0.60.80.90.9-0.80.9-0.6
Intermittent access day 1 total infusions1.02.95.4-1.3-1.4-2.02.3-1.4-1.01.21.92.01.7-1.71.7-1.9
Intermittent access day 15 total infusions0.30.71.90.1-0.4-1.01.1-0.5-0.61.41.01.00.8-0.80.8-0.8
Intermittent access terminal intake (last 3 days)0.30.51.40.2-0.2-0.80.9-0.60.11.20.80.90.7-0.70.7-0.7
Intermittent access total infusions0.81.01.9-0.2-0.5-1.21.4-0.8-0.11.31.21.20.9-1.01.0-1.1
Intermittent access day 1 locomotion0.10.21.0-0.0-0.2-0.51.00.1-0.31.00.60.50.3-0.00.3-0.3
Intermittent access day 15 total locomotion0.20.81.30.91.01.0-0.90.90.6-0.0-1.0-1.0-0.91.0-0.91.1
Intermittent access total locomotion0.10.20.70.60.60.10.10.40.40.8-0.1-0.2-0.30.3-0.20.3
Intermittent access standard deviation0.52.64.02.02.01.7-1.31.61.80.4-1.7-1.7-1.71.6-1.61.2
Left kidney weight1.713.916.83.74.14.1-3.83.53.9-0.8-3.9-4.0-3.93.8-3.93.8
Right kidney weight2.014.318.23.54.04.2-3.73.83.7-1.1-4.2-4.3-4.04.0-4.03.6
Cocaine induced anxiety0.10.20.9-0.5-0.20.3-0.30.2-0.3-0.9-0.4-0.5-0.20.2-0.20.3
Post-drug Anxiety0.30.40.60.40.40.7-0.70.40.5-0.8-0.7-0.8-0.60.6-0.60.8
Baseline Anxiety0.10.10.30.60.40.5-0.50.20.6-0.0-0.3-0.3-0.30.2-0.30.2
Tail length1.05.514.51.72.02.7-3.5-0.23.8-3.1-2.7-2.0-1.61.2-1.61.5
Length with tail2.19.518.51.82.73.7-4.30.84.2-3.7-3.7-3.1-2.72.2-2.82.3
Length without tail2.111.116.31.72.94.0-3.72.63.1-3.2-4.0-4.0-3.53.3-3.72.8
Times rat made contact with spout1.01.24.1-0.1-0.4-1.20.9-0.4-1.22.01.51.20.8-1.20.9-0.6
Lifetime Intake0.60.71.4-0.3-0.4-1.01.2-0.60.01.11.01.10.8-0.90.8-1.1
Liver weight, left1.32.27.50.40.81.8-2.00.21.4-2.7-1.8-1.5-1.11.3-1.20.8
Liver weight, right0.81.58.8-0.40.31.2-1.7-0.71.4-3.0-1.3-0.8-0.60.3-0.70.4
Locomotor activity0.71.03.00.90.91.1-1.7-0.31.6-1.3-1.1-0.9-0.70.4-0.60.8
Locomotor testing distance0.30.71.70.60.60.9-1.3-0.31.1-1.2-0.8-0.7-0.60.5-0.60.7
Locomotor testing rearing0.41.52.41.01.21.5-1.40.61.4-1.3-1.5-1.2-1.21.3-1.20.9
Locomotion in novel chamber0.10.10.40.60.40.2-0.30.30.10.1-0.3-0.3-0.30.3-0.30.2
Locomotion in novel chamber post-restriction0.61.92.81.41.61.5-1.21.41.4-0.1-1.3-1.5-1.51.5-1.51.7
Fecal boli incidents, locomotor time 10.10.31.7-0.1-0.2-0.51.30.10.10.60.40.30.30.20.2-0.7
Change in fecal boli incidents, locomotor task1.01.04.1-0.10.31.3-1.8-0.10.7-2.0-1.2-0.8-0.70.3-0.70.7
Time >=10cm from walls, locomotor time 13.13.96.00.71.52.4-2.31.61.6-2.3-2.2-2.2-2.12.2-2.21.7
Bouts of movement, locomotor time 10.30.41.4-0.8-0.8-0.70.3-0.4-1.20.10.70.40.7-0.60.7-0.4
Total resting periods, locomotor time 10.30.30.9-0.7-0.7-0.60.3-0.4-1.0-0.10.60.30.6-0.50.7-0.4
Rest time, locomotor task time 10.10.20.40.1-0.2-0.30.3-0.70.5-0.40.10.30.4-0.30.4-0.7
Distance moved, locomotor task time 10.20.61.20.10.70.8-1.10.80.4-0.2-0.7-0.8-0.90.6-0.91.1
Vertical activity count, locomotor time 10.21.52.60.71.21.3-1.51.50.40.1-1.0-1.3-1.51.0-1.41.6
Time >=10cm from walls, locomotor time 20.72.14.40.21.11.9-2.10.71.7-1.9-1.6-1.4-1.41.1-1.51.1
Bouts of movement, locomotor time 20.00.10.30.1-0.0-0.0-0.5-0.50.2-0.20.10.20.3-0.50.3-0.2
Total resting periods, locomotor time 20.10.31.2-0.2-0.4-0.3-0.3-1.10.2-0.50.30.50.7-0.90.7-0.6
Rest time, locomotor task time 20.20.42.7-0.8-0.60.2-0.1-0.4-0.4-1.6-0.4-0.20.20.10.1-0.8
Distance moved, locomotor task time 20.60.81.70.31.10.8-0.61.30.70.7-0.6-0.8-1.10.8-1.11.3
Vertical activity count, locomotor time 20.40.81.60.51.01.0-0.91.20.90.3-0.6-0.9-1.10.7-1.11.3
Light reinforcement 10.42.03.40.71.11.7-1.41.80.1-0.6-1.7-1.8-1.71.8-1.71.2
Light reinforcement 20.41.01.60.10.71.3-1.01.00.1-1.1-1.2-1.1-1.21.2-1.30.9
Bone: marrow area2.04.913.61.11.62.5-2.9-0.13.1-3.7-2.8-1.9-1.61.6-1.71.2
Bone: maximum diameter0.40.85.0-1.3-0.9-0.0-0.5-1.2-0.1-2.2-0.10.30.5-0.70.4-0.5
Bone: maximum force1.22.43.51.31.61.7-1.51.81.2-0.4-1.7-1.9-1.71.7-1.71.6
Bone: maximum moment0.91.62.41.11.31.4-1.11.51.2-0.4-1.4-1.5-1.41.4-1.41.1
Mean time between licks in bursts0.31.53.4-1.5-1.5-0.90.5-1.8-0.4-1.70.60.81.4-1.01.3-1.4
Mean num. licks in bursts0.30.86.01.20.8-0.20.50.80.12.50.50.3-0.30.2-0.20.8
Cd content in liver0.30.31.2-0.00.20.10.91.1-0.50.8-0.1-0.3-0.40.7-0.50.1
Co content in liver1.72.03.11.41.61.5-0.91.71.20.3-1.3-1.5-1.61.5-1.61.8
Cu content in liver1.01.24.0-0.4-0.7-1.41.0-0.3-1.72.01.30.90.7-1.10.8-0.3
Fe content in liver0.70.91.81.11.20.8-0.21.40.80.8-0.8-0.9-1.01.2-1.00.8
K content in liver0.60.61.4-0.8-1.0-0.90.9-0.5-1.20.20.70.80.8-0.50.8-0.9
Mg content in liver1.41.53.0-1.7-1.6-1.00.5-1.5-1.4-1.40.71.01.2-1.01.1-1.3
Mn content in liver1.11.25.8-2.1-1.2-0.2-0.2-1.4-0.6-2.40.20.40.5-0.80.4-1.0
Na content in liver0.10.10.4-0.0-0.1-0.4-0.1-0.1-0.70.60.30.20.3-0.40.40.1
Rb content in liver0.10.10.6-0.2-0.4-0.20.70.2-0.8-0.10.10.20.20.30.1-0.4
Se content in liver2.42.88.6-1.9-1.8-1.3-0.0-2.9-1.0-1.91.21.61.6-2.11.5-1.2
Sr content in liver0.20.20.80.20.40.5-0.10.20.9-0.6-0.5-0.4-0.30.3-0.4-0.2
Zn content in liver0.10.10.4-0.4-0.3-0.20.2-0.50.0-0.6-0.00.30.1-0.10.1-0.4
Bone: minimum diameter0.61.17.3-0.70.01.0-1.4-0.30.8-2.7-1.1-0.8-0.50.4-0.60.5
Time in familiar zone, hab. session 11.92.17.60.1-0.8-1.72.0-0.3-1.42.71.91.51.2-1.11.3-0.7
Time in novel zone, hab. session 11.82.15.10.41.01.7-1.90.41.7-2.3-1.9-1.5-1.21.2-1.30.5
Total zone transitions, hab. session 10.30.51.0-0.6-0.9-0.70.7-0.6-1.00.10.70.60.7-0.50.7-0.7
Total locomotion distance, hab. session 10.30.51.2-0.7-0.8-0.80.9-0.5-1.10.20.70.60.7-0.30.7-0.6
Locomotion velocity, hab. session 10.20.30.7-0.5-0.7-0.60.7-0.6-0.80.10.60.50.6-0.30.6-0.4
Time in familiar zone, hab. session 20.30.41.31.10.50.2-0.20.9-0.21.0-0.2-0.5-0.40.5-0.30.7
Time in novel zone, hab. session 20.10.10.4-0.20.10.1-0.1-0.40.7-0.3-0.10.20.0-0.2-0.0-0.6
Total zone transitions, hab. session 20.10.10.5-0.1-0.10.3-0.00.6-0.7-0.1-0.3-0.4-0.30.5-0.30.2
Total locomotion distance, hab. session 20.40.52.7-0.8-0.8-0.50.90.1-1.60.20.40.30.30.10.3-0.6
Locomotion velocity, hab. session 20.70.93.7-1.3-1.2-0.81.1-0.3-1.90.00.80.70.7-0.30.6-0.8
Novel to familiar place preference ratio0.20.30.9-0.4-0.5-0.60.5-0.5-0.30.20.60.60.6-0.70.6-1.0
Novelty place preference0.20.30.9-0.3-0.4-0.50.3-0.6-0.00.10.40.60.6-0.70.6-1.0
Time in novel zone, NPP test0.20.20.9-0.2-0.2-0.40.1-0.60.20.00.30.50.5-0.60.5-0.9
Total zone transitions, NPP test1.21.83.3-1.4-1.6-1.31.8-0.9-1.70.41.31.31.3-0.81.2-1.6
Total locomotion distance, NPP test0.91.33.6-1.3-1.2-1.11.9-0.3-1.60.61.11.00.9-0.40.8-1.4
Locomotion velocity, NPP test1.41.94.9-1.7-1.6-1.42.2-0.5-2.10.71.41.21.1-0.61.0-1.6
Intraocular pressure0.20.31.90.30.1-0.20.90.8-0.41.40.50.30.10.40.10.4
Delta distance traveled before/after self-admin0.60.73.01.21.00.7-1.2-0.41.7-0.1-0.7-0.3-0.4-0.0-0.40.7
Delta ambulatory time before/after self-admin0.40.72.11.00.90.8-1.4-0.41.5-0.5-0.9-0.4-0.50.0-0.40.6
Parametrial fat weight2.25.210.02.02.42.3-1.43.20.80.5-2.2-2.4-2.72.7-2.62.7
Pavlov. Cond. lever latency5.56.99.83.13.12.7-2.12.91.91.1-2.4-2.6-3.02.8-2.92.9
Pavlov. Cond. magazine entry latency3.03.87.3-2.0-2.2-1.90.9-2.7-1.2-0.71.82.02.2-2.52.2-1.9
Pavlov. Cond. change in total contacts1.41.63.4-1.4-1.4-1.20.4-1.9-0.6-0.81.11.21.4-1.71.4-1.0
Pavlov. Cond. index score4.65.89.1-2.9-2.8-2.31.5-3.0-1.8-1.22.22.32.7-2.82.6-2.4
Pavlov. Cond. latency score4.76.09.0-3.0-2.9-2.41.5-3.0-1.8-1.32.22.32.7-2.82.6-2.5
Pavlov. Cond. lever contacts3.94.78.8-3.0-2.7-2.11.7-2.4-1.7-1.41.82.02.4-2.22.2-2.3
Pavlov. Cond. magazine entry number2.02.64.71.71.81.6-0.92.21.00.6-1.5-1.6-1.92.0-1.81.6
Pavlov. Cond. intertrial magazine entries0.50.63.00.70.60.10.71.2-0.21.7-0.1-0.4-0.60.7-0.60.5
Pavlov. Cond. lever-magazine prob. diff.4.75.99.0-2.9-2.8-2.41.5-3.0-1.8-1.12.32.42.7-2.82.6-2.4
Pavlov. Cond. response bias3.34.16.5-2.5-2.4-2.01.2-2.6-1.5-1.01.81.92.2-2.42.1-1.9
Pavlov. Cond. lever latency0.40.52.0-0.30.20.9-0.80.40.2-1.4-0.8-0.7-0.60.7-0.70.5
Pavlov. Cond. magazine entry latency0.30.51.0-0.5-0.6-0.60.6-1.0-0.2-0.20.60.80.7-0.60.7-1.0
Pavlov. Cond. change in total contacts0.10.30.70.50.0-0.50.4-0.60.50.80.60.60.5-0.50.6-0.3
Pavlov. Cond. index score0.30.40.8-0.1-0.4-0.80.7-0.90.10.60.70.80.7-0.70.8-0.8
Pavlov. Cond. latency score0.20.30.60.2-0.2-0.60.5-0.70.20.60.50.60.5-0.50.6-0.6
Pavlov. Cond. lever contacts0.20.31.50.3-0.1-0.70.6-0.2-0.11.20.60.50.4-0.50.5-0.4
Pavlov. Cond. magazine entry number0.10.10.20.10.20.3-0.40.30.1-0.1-0.3-0.3-0.30.2-0.20.5
Pavlov. Cond. intertrial magazine entries0.30.61.2-1.0-1.0-0.70.1-1.1-0.7-0.80.50.50.9-0.90.9-0.4
Pavlov. Cond. lever-magazine prob. diff.0.20.30.6-0.1-0.3-0.70.6-0.70.00.50.70.70.6-0.70.6-0.7
Pavlov. Cond. response bias0.50.71.1-0.4-0.6-1.10.9-0.8-0.50.71.01.00.9-1.00.9-0.8
Time in closed arm before self-admin0.00.10.3-0.00.10.2-0.3-0.50.5-0.5-0.30.00.00.1-0.00.2
Time in closed arm after self-admin0.10.10.20.40.20.3-0.00.10.4-0.3-0.4-0.2-0.20.4-0.2-0.1
Time in open arm before self-admin1.11.42.3-0.9-1.1-1.30.8-1.4-0.80.21.21.41.3-1.51.3-1.2
Time in open arm after self-admin0.40.51.1-0.0-0.4-0.80.6-1.00.10.50.81.00.7-0.80.7-0.6
Bone: periosteal estimation1.33.07.10.91.32.0-2.50.32.2-2.7-2.2-1.7-1.41.3-1.41.3
Bone: periosteal perimeter0.40.74.5-0.50.00.8-1.4-0.40.6-2.1-0.8-0.6-0.3-0.1-0.40.5
Bone: post-yield work0.30.53.5-0.2-0.00.6-0.40.00.5-1.9-0.9-0.6-0.20.7-0.3-0.2
Progressive ratio test 1 active lever presses0.20.30.8-0.5-0.4-0.60.8-0.60.10.40.60.60.5-0.50.5-0.9
Progressive ratio test 1 breakpoint0.20.30.8-0.5-0.3-0.50.8-0.60.20.30.50.60.5-0.50.5-0.9
Progressive ratio test 1 inactive lever presses0.10.20.90.40.30.20.40.9-0.20.7-0.3-0.5-0.40.6-0.40.2
Progressive ratio test 2 active lever presses0.50.61.2-0.4-0.7-1.01.1-0.4-1.00.90.90.80.8-0.70.8-0.8
Progressive ratio test 2 breakpoint0.60.81.4-0.4-0.7-1.11.2-0.4-1.01.01.00.90.8-0.80.9-0.8
Progressive ratio test 2 inactive lever presses0.30.81.7-1.0-0.9-0.81.1-1.2-0.1-0.20.70.91.0-0.90.9-1.3
Incentive Sensitization - Responses0.20.61.5-0.4-0.8-0.90.7-0.6-1.20.40.70.70.9-0.70.9-0.6
Incentive Sensitization - Breakpoint0.30.61.7-0.3-0.7-0.90.8-0.5-1.30.50.70.70.8-0.60.9-0.5
Sum of active levers in priming session hrs 5-60.50.51.4-0.6-0.6-0.70.5-1.20.3-0.20.80.90.8-0.80.7-0.6
Progressive ratio2.77.912.03.53.13.0-2.92.92.5-0.1-3.1-2.9-2.92.8-2.82.7
Food seeking constrained by brief footshock0.10.10.60.30.2-0.30.3-0.20.20.80.20.30.1-0.40.20.1
Seeking ratio, punishment vs. effort2.65.77.5-2.7-2.5-2.52.2-2.7-1.80.12.62.52.6-2.62.5-2.3
Retroperitoneal fat weight0.10.51.40.30.60.6-0.01.2-0.30.3-0.5-0.8-0.90.9-1.01.0
Reaction time number correct0.51.83.31.81.71.2-0.51.81.21.2-1.2-1.3-1.31.4-1.21.2
Reaction time mean minus median0.42.33.6-1.9-1.9-1.51.2-1.7-1.3-0.71.31.51.7-1.51.6-1.5
Reaction time mean minus median AUC0.53.65.1-2.3-2.2-2.01.9-2.0-1.5-0.41.92.02.1-1.92.0-1.9
Reaction time num false alarms0.10.21.2-0.5-0.40.0-0.6-0.6-0.3-1.1-0.1-0.00.3-0.40.3-0.0
Reaction time num false alarms AUC0.10.31.7-0.4-0.20.2-1.0-0.7-0.0-1.3-0.3-0.20.2-0.40.20.1
Reaction time trials correct on left0.51.83.31.81.71.2-0.51.81.21.2-1.2-1.3-1.31.4-1.21.2
Reaction time trials on left0.51.83.21.81.71.1-0.51.71.21.1-1.2-1.3-1.31.4-1.21.2
Reaction time mean0.92.05.3-2.3-1.9-1.01.0-1.5-1.3-1.41.01.11.4-1.21.2-1.5
Reaction time mean AUC0.82.05.2-2.3-1.9-1.11.1-1.5-1.3-1.31.11.21.4-1.21.2-1.4
Median of all reaction times0.71.13.6-1.9-1.4-0.60.7-1.0-0.9-1.40.60.70.9-0.80.7-1.1
Reaction time omissions0.50.92.2-1.5-1.2-0.70.7-1.0-0.8-1.10.40.40.9-0.60.8-1.2
Reaction time false alarm rate0.91.23.4-1.4-1.2-0.6-0.5-1.8-0.7-1.80.50.71.0-1.31.0-0.7
Reaction time premature initiation rate0.30.41.00.60.80.7-0.40.41.0-0.2-0.8-0.5-0.70.9-0.70.3
Reaction time premature initiations0.72.13.31.71.81.5-0.91.41.70.4-1.5-1.4-1.51.7-1.51.2
Std. dev. reaction times0.82.75.2-2.1-2.0-1.40.9-2.3-1.0-1.41.31.51.8-1.81.7-1.6
Reaction time trials completed0.51.83.21.81.71.1-0.51.71.21.1-1.2-1.3-1.31.4-1.21.2
Reaction time trials AUC0.51.83.31.71.61.2-0.51.81.11.1-1.2-1.4-1.31.5-1.21.2
Run reversals in cocaine runway, females0.20.21.00.60.40.00.50.60.11.00.10.1-0.30.4-0.3-0.2
Run reversals in cocaine runway, males0.60.62.4-0.8-0.8-0.50.6-1.1-0.3-0.50.60.80.8-0.40.8-1.5
Latency to leave start box in cocaine runway0.40.62.2-1.5-1.1-0.60.4-0.7-0.9-1.10.40.40.6-0.60.5-0.5
Latency to leave start box in cocaine runway, F0.50.71.9-1.4-1.1-0.80.7-0.7-1.0-0.60.70.70.8-0.60.7-0.4
Latency to leave start box in cocaine runway, M0.20.20.9-0.4-0.10.3-0.50.2-0.1-0.9-0.6-0.5-0.30.1-0.30.1
Std. dev. time between licks in bursts0.51.06.8-1.1-0.9-0.1-0.5-1.60.3-2.6-0.30.20.7-0.50.6-0.7
Total sessions with >9 infusions0.40.50.8-0.1-0.3-0.70.7-0.80.20.80.80.90.7-0.90.7-0.9
Short access day 1 total inactive lever presses0.40.81.8-1.0-0.8-0.70.8-1.40.4-0.50.60.90.9-1.10.8-1.1
Short access day 10 total inactive lever presses0.00.21.3-0.4-0.40.2-0.10.2-1.2-0.7-0.4-0.30.00.2-0.0-0.2
Short access day 1 total infusions0.61.22.3-1.0-0.8-1.21.1-1.30.00.41.11.41.1-1.31.0-1.5
Short access day 10 total infusions0.40.71.5-0.3-0.5-1.01.2-0.5-0.41.11.11.00.8-0.70.8-0.9
Short access total infusions0.71.01.7-0.7-0.6-1.11.3-0.9-0.00.81.11.20.9-1.10.9-1.3
Short access day 1 locomotion0.50.91.9-1.0-1.1-0.90.9-0.8-1.4-0.00.90.91.0-0.71.0-1.0
Short access day 10 total locomotion0.62.45.20.91.31.9-2.30.21.7-2.0-1.9-1.7-1.21.3-1.31.1
Short access total locomotion0.10.20.8-0.10.20.6-0.5-0.20.5-0.9-0.5-0.4-0.20.4-0.3-0.1
One hour access (0.3 mA shock)1.41.64.7-1.0-1.5-1.31.2-0.7-2.20.51.21.21.3-1.01.3-1.4
Compulsive drug intake0.60.94.5-1.4-1.20.1-0.5-0.2-1.8-2.1-0.3-0.20.30.20.2-0.4
One hour access (shock baseline)0.30.93.80.3-0.2-1.01.3-0.2-0.42.01.11.10.7-0.80.8-0.6
Social response proportion0.50.71.90.00.60.9-1.20.11.3-1.4-0.8-0.6-0.70.2-0.80.4
Social responses0.50.61.80.30.60.8-1.3-0.31.2-1.1-0.7-0.6-0.70.0-0.70.9
Social time0.60.95.0-1.4-1.1-0.0-0.5-1.1-0.9-2.2-0.20.10.5-0.50.4-0.7
Soleus weight0.82.318.3-1.5-0.41.2-1.8-1.00.9-4.3-1.4-0.6-0.30.2-0.5-0.4
Bone: stiffness0.91.63.51.11.21.2-1.01.90.30.1-1.4-1.6-1.41.4-1.41.5
Tibialis anterior weight0.10.51.00.90.70.4-0.31.00.01.0-0.4-0.6-0.80.7-0.71.0
Time to tail flick, vehicle, before self-admin0.40.52.5-0.4-0.30.2-0.51.0-1.6-0.2-0.0-0.7-0.40.4-0.31.2
Time to tail flick, vehicle, after self-admin0.30.61.4-1.2-0.9-0.60.3-1.0-0.6-0.40.60.70.8-0.90.8-0.7
Time to tail flick, test, before self-admin0.10.10.40.4-0.1-0.3-0.10.4-0.60.60.1-0.00.1-0.20.20.4
Time to tail flick, test, after self-admin2.22.33.9-0.8-1.5-2.01.8-1.1-1.61.11.71.71.7-1.51.7-1.2
Delta time to tail flick, vehicle, before/after SA1.92.03.8-1.1-1.0-1.61.7-1.4-0.21.01.51.71.4-1.61.4-1.9
Delta time to tail flick, test, before/after SA0.40.41.5-0.5-0.6-0.81.2-0.1-0.80.60.70.60.5-0.20.5-0.6
Tibia length1.84.99.31.51.72.6-2.80.82.5-3.1-2.9-2.3-1.82.3-2.01.4
Ambulatory time before self-admin0.00.10.40.1-0.00.10.10.4-0.2-0.2-0.1-0.3-0.20.6-0.20.2
Ambulatory time after self-admin0.81.22.11.11.11.2-1.40.51.4-0.9-1.3-1.1-1.01.0-1.01.0
Bone: tissue strength0.10.20.40.30.40.40.00.40.60.0-0.4-0.4-0.40.6-0.50.0
Total heroin consumption0.00.00.2-0.1-0.20.1-0.3-0.2-0.2-0.4-0.10.00.0-0.00.00.2
Bone: trabecular number1.42.67.0-0.8-1.3-1.92.70.4-2.42.31.71.31.3-0.51.3-1.5
Bone: trabecular spacing2.13.07.00.91.52.1-2.70.12.5-2.0-1.8-1.5-1.50.9-1.51.7
Bone: trabecular thickness0.71.03.1-0.3-0.6-1.11.80.6-1.71.60.90.60.60.00.6-0.6
Bone: trabecular tissue density0.10.20.40.50.1-0.2-0.1-0.50.60.00.00.20.5-0.30.6-0.7
Water consumed over 24 hours0.10.10.9-0.5-0.20.1-0.5-0.4-0.0-0.9-0.2-0.00.0-0.2-0.0-0.3
Number of responses in last shaping day0.60.73.3-0.6-0.20.3-0.9-1.51.3-1.8-0.40.20.3-0.60.2-0.6