Hub : Genes

Pamr1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Pamr1 0.05 0.05 2.9e-06 0.04 0.04 0.04 0.04 8.5e-06 9.1e-06 6.4e-05 4.6e-05
2 OFC gene expression Pamr1 0.35 0.24 2.3e-05 0.14 0.16 0.14 0.15 3.3e-04 1.2e-04 2.7e-04 2.1e-04
3 LHb gene expression Pamr1 0.46 0.22 6.1e-09 0.26 0.26 0.25 0.25 8.8e-07 7.3e-07 1.3e-06 1.5e-06
4 PL gene expression Pamr1 0.44 0 0.0e+00 0.35 0.34 0.35 0.35 9.5e-40 2.9e-39 1.9e-40 5.0e-40
5 BLA gene expression Pamr1 0.48 0.19 0.0e+00 0.37 0.4 0.39 0.39 5.4e-21 1.5e-22 2.1e-22 6.0e-22
6 NAcc gene expression Pamr1 0.42 0 0.0e+00 0.33 0.09 0.34 0.04 9.7e-40 8.2e-11 6.0e-40 1.0e-05
7 IL gene expression Pamr1 0.67 0.23 3.4e-05 0.17 0.18 0.16 0.18 7.1e-05 3.3e-05 1.1e-04 3.4e-05
8 Brain gene expression Pamr1 0.73 0 0.0e+00 0.53 0.01 0.52 0.05 1.2e-57 5.1e-02 1.7e-56 2.0e-05
9 RMTg gene expression Pamr1 0.41 0.11 1.8e-11 0.25 0.28 0.27 0.32 2.6e-07 4.7e-08 6.7e-08 2.5e-09
10 Liver gene expression Pamr1 0.24 0.19 2.5e-10 0.08 0.08 0.07 0.08 8.0e-09 7.9e-09 3.0e-08 7.9e-09
11 pVTA gene expression Pamr1 0.24 0.04 0.0e+00 0.48 0.02 0.5 0.01 1.6e-23 5.0e-02 2.6e-24 1.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.61.01.51.21.11.1-1.01.0-1.01.0-0.90.90.9-0.8
Area under the delay curve0.60.60.8-0.7-0.7-0.80.7-0.80.8-0.80.9-0.8-0.80.8
BMI with tail0.00.10.80.90.50.5-0.00.2-0.10.0-0.20.4-0.1-0.3
BMI without tail0.10.31.41.20.80.8-0.10.4-0.30.2-0.40.40.0-0.2
Body weight0.10.53.21.80.80.8-0.60.5-0.40.3-0.40.5-0.0-0.5
Weight adjusted by age1.82.12.9-1.5-1.5-1.51.3-1.41.3-1.31.7-1.4-1.31.5
Bone surface0.10.31.21.10.60.6-0.40.4-0.30.3-0.40.40.1-0.4
Bone volume1.11.83.11.81.51.5-1.31.4-1.31.2-1.31.21.1-1.1
Breakpoint value in progressive ratio session0.80.91.4-1.2-1.1-1.01.0-1.01.0-0.90.9-0.8-0.70.8
Number of licking bursts0.00.10.20.40.20.2-0.40.2-0.20.2-0.10.00.00.0
Context. condit. distance diff. score5.16.28.41.62.02.1-2.92.5-2.72.8-2.72.52.7-2.6
Locomotion velocity, session 10.00.00.1-0.20.00.00.2-0.00.1-0.1-0.00.1-0.0-0.2
Locomotion distance, session 10.40.50.70.20.60.6-0.80.8-0.70.9-0.60.60.8-0.7
Locomotion velocity, session 20.00.00.1-0.3-0.1-0.10.2-0.10.2-0.10.30.1-0.1-0.1
Locomotion distance, session 20.30.40.50.70.70.7-0.70.7-0.60.6-0.40.50.5-0.5
Locomotion velocity, session 30.30.30.50.30.60.6-0.50.6-0.60.6-0.40.70.7-0.7
Locomotion distance, session 30.30.40.50.50.60.6-0.60.6-0.70.6-0.40.60.6-0.6
Stereotopy head waving bouts, day 30.50.61.1-0.20.60.6-0.80.8-0.81.0-0.80.71.1-0.6
Stereotopy head waving duration, day 30.91.11.60.41.01.0-1.11.1-1.11.2-1.01.11.3-1.0
Locomotion velocity, session 70.60.71.00.20.80.8-0.80.9-1.01.0-0.60.91.0-0.9
Locomotion distance, session 70.00.10.3-0.5-0.3-0.3-0.0-0.1-0.00.10.3-0.20.00.2
Stereotopy head waving bouts, day 70.30.30.6-0.10.30.3-0.50.5-0.50.6-0.80.70.8-0.7
Stereotopy head waving duration, day 70.00.00.1-0.2-0.00.00.1-0.00.1-0.0-0.10.20.1-0.2
Locomotion velocity, session 81.41.72.30.91.21.2-1.41.3-1.31.4-1.21.51.3-1.5
Locomotion distance, session 84.87.18.72.12.42.5-2.92.7-2.82.8-2.72.72.7-2.8
Degree of sensitization distance0.10.10.4-0.7-0.6-0.50.0-0.20.2-0.10.2-0.4-0.10.4
Degree of sensitization stereotypy0.00.00.1-0.2-0.2-0.20.3-0.30.3-0.20.00.1-0.1-0.2
Conditioned locomotion2.83.34.6-2.1-2.1-2.11.3-1.71.6-1.41.8-2.1-1.52.0
Cocaine response after cond. corrected2.02.22.5-1.4-1.5-1.51.5-1.51.5-1.41.5-1.6-1.41.5
Cocaine response after cond. not corrected0.60.60.8-0.6-0.8-0.80.9-0.80.8-0.80.8-0.9-0.80.8
Cocaine response before conditioning4.04.95.42.32.22.2-2.32.2-2.22.1-2.22.32.0-2.3
Saline control response0.60.81.51.21.01.0-0.80.8-0.90.8-0.80.90.8-0.9
Bone: connectivity density0.30.41.01.00.80.7-0.60.7-0.60.6-0.60.60.5-0.5
Bone: cortical apparent density0.10.20.3-0.3-0.4-0.40.3-0.40.4-0.40.3-0.5-0.40.6
Bone: cortical area0.50.81.70.4-0.5-0.51.0-0.91.0-1.21.1-0.8-1.30.7
Bone: cortical porosity0.20.20.5-0.7-0.6-0.60.4-0.50.5-0.40.3-0.4-0.30.4
Bone: cortical porosity0.30.30.4-0.5-0.7-0.60.6-0.60.6-0.60.5-0.5-0.50.4
Bone: cortical thickness1.01.73.0-0.1-0.8-0.91.6-1.41.5-1.71.5-1.2-1.71.1
Bone: cortical thickness6.37.38.3-2.1-2.7-2.72.6-2.82.8-2.82.9-2.8-2.92.7
Bone: cortical tissue density0.10.10.2-0.3-0.3-0.30.2-0.30.3-0.30.2-0.4-0.30.5
Condit. Reinf. active minus inactive responses1.01.11.50.81.11.1-1.21.1-1.11.1-1.11.01.1-0.9
Condit. Reinf. active-inactive response ratio0.80.81.91.41.01.0-0.90.8-0.80.7-1.00.90.6-0.8
Condit. Reinf. active responses0.30.40.70.40.60.6-0.80.7-0.70.7-0.50.50.6-0.4
Condit. Reinf. inactive responses0.10.10.5-0.7-0.4-0.40.1-0.20.1-0.10.6-0.4-0.20.4
Incentive salience index mean0.60.70.90.90.90.9-0.90.9-0.80.8-0.90.80.7-0.7
Condit. Reinf. lever presses0.20.21.01.00.70.6-0.30.3-0.20.1-0.20.40.0-0.3
Condit. Reinf. active minus inactive responses2.93.55.40.91.61.6-2.32.1-2.22.2-1.81.72.1-1.6
Condit. Reinf. active-inactive response ratio4.24.45.91.72.02.0-2.42.3-2.42.3-2.11.92.1-1.8
Condit. Reinf. active responses1.31.72.90.81.21.2-1.71.5-1.61.6-1.11.11.4-1.1
Condit. Reinf. inactive responses0.10.10.2-0.1-0.2-0.20.0-0.20.2-0.20.5-0.3-0.30.3
Condit. Reinf. lever presses0.81.11.60.61.01.0-1.21.2-1.31.2-0.91.01.2-0.9
Condit. Reinf. lever reinforcers received1.62.33.60.81.41.4-1.91.7-1.81.8-1.31.31.7-1.3
Conditioned reinforcement - actives1.91.93.11.81.71.7-1.21.4-1.31.2-1.11.21.0-1.2
Conditioned reinforcement - inactives3.33.710.33.22.62.5-1.41.7-1.61.2-1.61.61.0-1.6
Conditioned locomotion1.31.52.91.71.51.5-1.21.2-1.21.0-1.01.10.8-1.0
Patch foraging indifference point 0 sec0.00.10.2-0.4-0.4-0.4-0.1-0.20.0-0.10.2-0.3-0.10.3
Patch foraging indifference point AUC0.70.81.6-1.2-0.9-0.91.2-0.80.9-0.70.9-0.8-0.50.7
Delay disc. indifference point, 0s delay0.60.71.1-0.2-0.5-0.50.9-0.80.8-1.00.9-0.9-1.01.1
Delay disc. indifference point, 16s delay3.33.44.1-1.5-1.7-1.82.0-1.91.9-1.91.8-1.8-1.91.8
Delay disc. indifference point, 2s delay0.30.30.6-0.8-0.6-0.60.4-0.50.4-0.40.7-0.5-0.40.6
Delay disc. indifference point, 24s delay0.10.10.5-0.7-0.3-0.30.0-0.0-0.00.2-0.20.10.3-0.3
Delay disc. indifference point, 4s delay0.80.81.4-0.6-0.8-0.80.8-0.90.9-0.91.0-0.9-1.01.2
Delay disc. indifference point, 8s delay0.30.30.40.30.40.4-0.60.5-0.50.5-0.40.60.6-0.6
Indifference point function ln k0.10.21.11.10.20.2-0.1-0.20.2-0.40.3-0.1-0.60.2
Indifference point function log k0.10.21.11.10.20.2-0.1-0.20.2-0.40.3-0.1-0.60.2
Patch foraging total patch changes 0 sec0.00.00.1-0.3-0.2-0.2-0.3-0.0-0.10.00.1-0.20.00.2
Patch foraging total patch changes 12 sec0.40.50.70.50.70.7-0.60.8-0.80.8-0.70.70.8-0.7
Patch foraging total patch changes 18 sec0.10.10.6-0.8-0.3-0.3-0.0-0.0-0.10.10.1-0.20.20.1
Patch foraging total patch changes 24 sec0.20.21.2-1.1-0.7-0.70.5-0.40.2-0.10.2-0.20.10.1
Patch foraging total patch changes 6 sec0.00.00.2-0.5-0.0-0.0-0.00.1-0.20.20.1-0.00.3-0.0
Patch foraging time to switch 0 sec0.40.71.3-0.00.60.6-0.90.9-1.01.0-0.90.81.1-0.8
Patch foraging water rate 0 sec0.40.71.30.1-0.7-0.70.8-0.90.9-1.01.0-0.7-1.10.8
Patch foraging water rate 12 sec0.50.81.0-0.6-1.0-1.00.8-1.01.0-0.91.0-0.8-1.00.7
Patch foraging water rate 18 sec0.20.31.01.00.50.5-0.60.4-0.50.4-0.30.40.2-0.5
Patch foraging water rate 24 sec0.91.22.0-0.6-1.1-1.11.1-1.21.1-1.21.4-1.0-1.21.0
Patch foraging water rate 6 sec0.20.30.40.0-0.6-0.60.4-0.60.6-0.60.5-0.4-0.70.4
Seeking ratio, delayed vs. immediate footshock0.60.71.50.7-0.1-0.21.0-0.70.8-1.00.8-0.9-1.21.0
Distance traveled before self-admin0.10.10.80.90.30.3-0.0-0.10.0-0.30.10.0-0.40.1
Distance traveled after self-admin0.10.10.50.70.40.30.00.0-0.1-0.2-0.20.1-0.30.1
Extensor digitorum longus weight0.41.61.9-1.1-1.3-1.31.2-1.31.2-1.21.4-1.3-1.21.3
Bone: elastic displacement2.22.53.5-1.5-1.6-1.61.9-1.71.6-1.61.6-1.5-1.51.4
Bone: elastic work2.22.94.0-1.3-1.6-1.62.0-1.81.8-1.81.8-1.7-1.71.5
Bone: endosteal estimation0.20.50.8-0.5-0.8-0.80.4-0.70.6-0.50.8-0.9-0.70.8
Bone: endosteal perimeter0.20.40.70.80.60.6-0.80.7-0.70.7-0.50.50.5-0.5
Epididymis fat weight0.51.11.81.31.21.2-0.80.9-0.90.8-1.11.20.8-1.2
Delta time in closed arm before/after self-admin0.70.71.50.10.50.5-1.20.9-1.01.1-0.70.71.0-0.6
Delta time in open arm before/after self-admin2.52.43.6-0.7-1.2-1.21.8-1.71.7-1.91.5-1.5-1.91.5
Diff in mean of infusions in LGA sessions2.42.64.0-0.6-1.2-1.21.7-1.71.9-2.01.6-1.6-2.01.8
Delay discount exponential model param0.50.50.70.70.80.8-0.70.7-0.70.7-0.80.70.7-0.8
Extinction: sum of active levers before priming1.41.42.10.70.91.0-1.21.2-1.01.3-1.31.41.4-1.4
Active lever presses in extinction session 62.72.63.80.81.21.3-1.61.6-1.61.9-1.81.71.9-1.9
Bone: final force0.20.30.5-0.1-0.3-0.40.6-0.50.6-0.60.7-0.5-0.70.4
Bone: final moment0.30.60.8-0.4-0.6-0.60.8-0.80.8-0.80.9-0.7-0.90.7
Food consumed during 24 hour testing period4.45.37.72.82.62.6-2.22.3-2.22.0-2.22.31.9-2.1
Glucose2.74.14.81.82.02.0-2.22.2-2.22.1-1.91.92.1-1.8
Heart weight0.10.20.7-0.9-0.6-0.60.1-0.20.10.10.2-0.30.10.1
Delay discount hyperbolic model param0.40.50.60.70.70.7-0.60.7-0.70.7-0.80.70.6-0.8
Intermittent access intake day 1-15 change0.00.00.10.30.10.10.00.00.0-0.0-0.00.0-0.1-0.1
Intermittent access intake escalation0.20.20.30.50.40.4-0.40.4-0.30.4-0.40.40.3-0.5
Intermittent access intake escalation 20.60.62.11.41.01.0-0.60.6-0.50.4-0.60.50.2-0.5
Intermitt. access day 1 inactive lever presses0.30.30.5-0.1-0.5-0.50.4-0.60.6-0.60.4-0.7-0.70.7
Intermitt. access day 15 inactive lever presses0.50.63.82.01.11.0-0.20.3-0.2-0.20.00.2-0.40.0
Intermitt. access escalation Index0.30.20.50.10.30.3-0.40.5-0.40.5-0.70.60.6-0.7
Intermittent access day 1 total infusions3.03.54.32.12.02.0-2.01.9-1.91.8-1.71.71.6-1.7
Intermittent access day 15 total infusions2.93.25.02.22.12.1-1.81.8-1.71.6-1.61.71.4-1.7
Intermittent access terminal intake (last 3 days)2.93.26.42.52.22.2-1.81.8-1.71.4-1.61.51.2-1.4
Intermittent access total infusions2.12.46.42.52.12.0-1.41.5-1.31.1-1.21.20.8-1.1
Intermittent access day 1 locomotion1.51.62.21.31.31.3-1.51.3-1.31.3-1.21.01.2-1.1
Intermittent access day 15 total locomotion2.52.73.11.51.71.7-1.81.7-1.71.6-1.61.51.5-1.6
Intermittent access total locomotion1.11.33.11.81.51.4-1.21.1-1.00.9-0.80.80.6-0.9
Intermittent access standard deviation2.93.16.42.52.22.1-1.81.7-1.61.4-1.61.41.1-1.3
Left kidney weight0.30.92.51.61.01.0-1.00.8-0.90.7-0.60.80.5-0.8
Right kidney weight0.30.82.01.41.01.0-0.70.7-0.80.6-0.50.90.5-1.0
Cocaine induced anxiety0.50.51.20.6-0.1-0.20.7-0.60.7-0.90.7-0.7-1.10.9
Post-drug Anxiety1.21.42.3-0.0-0.6-0.71.4-1.21.2-1.51.3-1.1-1.51.4
Baseline Anxiety2.62.73.4-1.7-1.6-1.61.8-1.71.6-1.71.7-1.5-1.61.6
Tail length0.20.61.51.20.80.8-0.60.7-0.60.6-0.80.60.5-0.7
Length with tail0.10.21.51.20.40.4-0.50.2-0.20.1-0.20.0-0.1-0.1
Length without tail0.00.10.40.60.10.1-0.4-0.0-0.0-0.10.1-0.1-0.30.1
Times rat made contact with spout0.00.00.10.30.20.2-0.00.1-0.0-0.1-0.2-0.1-0.20.2
Lifetime Intake2.12.46.92.62.12.0-1.41.4-1.31.0-1.11.20.8-1.1
Liver weight, left0.60.91.40.40.80.8-1.01.0-1.11.1-1.00.81.2-0.9
Liver weight, right0.61.01.51.21.11.1-1.21.0-1.00.9-0.90.90.8-0.8
Locomotor activity0.40.71.20.10.50.5-0.80.8-1.01.0-0.71.01.1-1.1
Locomotor testing distance2.03.34.21.31.61.6-1.81.8-2.02.0-1.82.02.0-2.0
Locomotor testing rearing1.42.23.50.40.91.0-1.71.5-1.71.8-1.41.51.9-1.7
Locomotion in novel chamber0.20.21.01.00.60.6-0.30.3-0.40.1-0.20.4-0.0-0.3
Locomotion in novel chamber post-restriction0.81.01.8-1.3-1.2-1.21.1-1.01.0-0.81.0-0.9-0.80.7
Fecal boli incidents, locomotor time 16.67.211.0-3.3-3.1-3.02.3-2.72.6-2.42.4-2.7-2.12.6
Change in fecal boli incidents, locomotor task6.86.47.72.72.82.7-2.62.6-2.52.4-2.52.42.2-2.3
Time >=10cm from walls, locomotor time 10.60.61.2-0.50.10.2-0.70.6-0.80.9-0.80.91.1-1.0
Bouts of movement, locomotor time 13.13.44.4-1.2-1.6-1.61.8-1.91.9-2.02.0-1.9-2.02.1
Total resting periods, locomotor time 12.42.63.6-1.1-1.5-1.51.5-1.61.6-1.71.7-1.7-1.71.9
Rest time, locomotor task time 10.70.71.0-0.9-0.9-0.90.6-0.80.8-0.80.8-1.0-0.80.9
Distance moved, locomotor task time 10.60.73.11.81.21.1-0.40.6-0.40.2-0.50.60.0-0.5
Vertical activity count, locomotor time 10.00.00.20.40.20.20.2-0.00.1-0.10.00.1-0.2-0.2
Time >=10cm from walls, locomotor time 26.06.37.42.52.62.6-2.42.5-2.52.4-2.62.62.3-2.7
Bouts of movement, locomotor time 20.00.00.1-0.4-0.1-0.1-0.20.2-0.20.3-0.3-0.10.30.0
Total resting periods, locomotor time 20.10.10.4-0.30.10.1-0.40.4-0.40.6-0.50.10.6-0.2
Rest time, locomotor task time 20.30.42.3-1.5-0.9-0.8-0.3-0.10.00.4-0.2-0.30.60.1
Distance moved, locomotor task time 20.80.95.22.31.11.00.5-0.10.4-0.80.40.1-1.10.2
Vertical activity count, locomotor time 20.40.52.81.70.90.80.20.10.1-0.40.00.3-0.6-0.2
Light reinforcement 10.10.10.60.80.40.4-0.10.1-0.1-0.1-0.10.0-0.20.1
Light reinforcement 20.50.71.40.3-0.4-0.40.8-0.90.9-1.10.8-0.8-1.20.9
Bone: marrow area0.20.50.8-0.5-0.8-0.80.5-0.70.6-0.50.8-0.9-0.70.8
Bone: maximum diameter0.10.20.40.6-0.1-0.10.4-0.40.4-0.50.6-0.3-0.70.3
Bone: maximum force0.10.10.30.3-0.1-0.10.2-0.30.3-0.40.5-0.3-0.50.3
Bone: maximum moment0.20.40.6-0.2-0.5-0.50.6-0.70.7-0.70.8-0.7-0.80.6
Mean time between licks in bursts0.20.31.0-1.0-0.9-0.90.0-0.40.3-0.10.3-0.5-0.10.5
Mean num. licks in bursts0.00.10.1-0.00.30.3-0.00.2-0.20.2-0.40.20.3-0.2
Cd content in liver2.02.22.61.31.61.6-1.31.5-1.51.5-1.61.61.5-1.5
Co content in liver2.12.43.1-1.5-1.5-1.51.8-1.61.7-1.61.6-1.5-1.51.4
Cu content in liver1.82.22.9-0.8-1.3-1.41.6-1.61.6-1.71.6-1.4-1.71.3
Fe content in liver0.30.31.9-1.4-0.7-0.70.3-0.40.3-0.20.3-0.5-0.10.5
K content in liver4.54.55.9-1.5-1.8-1.82.4-2.22.2-2.42.3-2.1-2.42.1
Mg content in liver4.85.06.2-1.4-1.9-2.02.5-2.32.3-2.42.4-2.3-2.52.2
Mn content in liver1.01.21.7-1.3-1.2-1.30.9-1.00.9-0.91.0-1.2-0.91.2
Na content in liver0.40.50.6-0.4-0.6-0.60.7-0.70.6-0.70.8-0.8-0.70.8
Rb content in liver1.72.23.3-1.5-1.3-1.31.8-1.51.6-1.61.5-1.3-1.41.2
Se content in liver4.65.76.2-2.2-2.4-2.42.5-2.42.4-2.32.3-2.5-2.32.4
Sr content in liver0.70.71.0-0.3-0.8-0.80.6-0.80.8-0.80.8-0.9-0.91.0
Zn content in liver0.30.40.6-0.5-0.5-0.50.8-0.70.7-0.70.7-0.3-0.60.3
Bone: minimum diameter0.10.21.11.10.20.20.1-0.10.2-0.30.4-0.1-0.50.0
Time in familiar zone, hab. session 10.10.10.4-0.6-0.5-0.50.4-0.40.3-0.20.2-0.2-0.1-0.0
Time in novel zone, hab. session 10.10.10.80.90.50.5-0.20.2-0.20.00.20.1-0.2-0.1
Total zone transitions, hab. session 13.34.75.11.82.12.1-2.22.2-2.22.2-2.22.22.2-2.3
Total locomotion distance, hab. session 12.23.14.11.11.51.5-2.01.9-1.82.0-2.01.72.0-1.7
Locomotion velocity, hab. session 11.72.43.90.91.31.3-1.71.6-1.51.7-2.01.51.8-1.6
Time in familiar zone, hab. session 20.40.51.00.3-0.3-0.31.0-0.80.8-1.00.6-0.5-0.90.4
Time in novel zone, hab. session 20.30.30.6-0.00.30.3-0.80.6-0.70.7-0.40.40.6-0.3
Total zone transitions, hab. session 21.82.32.71.61.71.6-1.51.5-1.51.4-1.51.51.4-1.5
Total locomotion distance, hab. session 20.50.61.00.30.50.6-1.00.8-0.81.0-1.00.71.0-0.7
Locomotion velocity, hab. session 20.30.40.70.20.40.4-0.80.7-0.60.8-0.90.50.8-0.6
Novel to familiar place preference ratio0.80.81.00.91.01.0-0.80.9-0.80.8-0.91.00.7-0.9
Novelty place preference0.60.70.80.80.90.9-0.70.8-0.70.7-0.90.90.6-0.8
Time in novel zone, NPP test0.50.50.60.60.80.8-0.60.7-0.70.6-0.70.80.5-0.7
Total zone transitions, NPP test0.10.11.0-1.0-0.4-0.40.0-0.00.00.20.0-0.20.30.1
Total locomotion distance, NPP test0.20.30.7-0.8-0.2-0.1-0.70.4-0.50.7-0.50.10.8-0.3
Locomotion velocity, NPP test0.20.30.7-0.6-0.0-0.0-0.70.5-0.50.8-0.60.20.8-0.3
Intraocular pressure0.30.40.6-0.20.40.5-0.50.6-0.60.7-0.60.80.8-0.7
Delta distance traveled before/after self-admin0.10.10.4-0.6-0.2-0.2-0.10.1-0.10.3-0.40.00.3-0.1
Delta ambulatory time before/after self-admin0.00.00.2-0.5-0.2-0.2-0.10.0-0.00.1-0.2-0.10.20.0
Parametrial fat weight1.01.92.51.61.51.5-1.01.3-1.31.2-1.31.61.2-1.6
Pavlov. Cond. lever latency0.40.50.9-0.8-0.8-0.80.6-0.70.6-0.60.9-0.8-0.60.7
Pavlov. Cond. magazine entry latency1.52.02.51.31.41.4-1.51.5-1.51.4-1.61.21.4-1.2
Pavlov. Cond. change in total contacts0.50.50.9-0.1-0.6-0.60.8-0.80.9-0.90.6-0.7-0.90.7
Pavlov. Cond. index score0.40.50.80.90.80.8-0.60.7-0.60.6-0.90.70.6-0.6
Pavlov. Cond. latency score0.40.50.90.90.80.8-0.60.7-0.60.6-0.90.70.6-0.6
Pavlov. Cond. lever contacts0.20.20.50.70.50.5-0.30.3-0.20.2-0.50.40.2-0.4
Pavlov. Cond. magazine entry number1.51.82.3-1.3-1.4-1.41.4-1.41.4-1.31.5-1.2-1.31.2
Pavlov. Cond. intertrial magazine entries0.00.00.2-0.4-0.1-0.1-0.20.1-0.10.20.10.10.1-0.1
Pavlov. Cond. lever-magazine prob. diff.0.30.40.70.80.70.7-0.50.6-0.50.5-0.80.50.5-0.5
Pavlov. Cond. response bias1.01.31.61.11.21.2-1.11.2-1.11.1-1.31.11.1-1.0
Pavlov. Cond. lever latency3.54.76.0-1.5-2.1-2.12.3-2.32.4-2.42.0-2.1-2.32.0
Pavlov. Cond. magazine entry latency0.91.01.30.91.21.1-1.11.1-1.11.0-1.00.90.9-0.7
Pavlov. Cond. change in total contacts0.81.11.31.01.21.1-1.01.1-1.21.0-0.81.11.0-1.1
Pavlov. Cond. index score2.22.83.41.41.71.7-1.81.8-1.81.7-1.51.61.6-1.4
Pavlov. Cond. latency score2.53.13.71.51.91.9-1.91.9-1.91.8-1.61.71.7-1.5
Pavlov. Cond. lever contacts2.94.04.81.52.02.0-2.12.1-2.22.1-1.82.02.1-2.0
Pavlov. Cond. magazine entry number0.50.60.8-0.6-0.9-0.90.9-0.90.9-0.80.7-0.6-0.70.5
Pavlov. Cond. intertrial magazine entries0.00.00.2-0.4-0.1-0.10.00.0-0.10.10.10.30.3-0.3
Pavlov. Cond. lever-magazine prob. diff.1.62.12.51.21.51.5-1.61.5-1.61.5-1.31.31.4-1.2
Pavlov. Cond. response bias2.63.64.51.31.91.9-2.12.0-2.12.1-1.81.82.0-1.7
Time in closed arm before self-admin0.20.20.90.90.70.6-0.30.4-0.30.2-0.40.40.2-0.4
Time in closed arm after self-admin0.70.71.40.70.70.7-1.20.9-1.01.0-0.70.70.9-0.6
Time in open arm before self-admin0.60.71.6-1.0-0.2-0.1-0.80.6-0.81.1-0.80.71.3-0.9
Time in open arm after self-admin1.11.22.1-1.5-1.2-1.21.3-1.11.1-1.00.9-1.0-0.90.9
Bone: periosteal estimation0.50.91.5-0.1-0.8-0.80.9-1.01.0-1.01.2-1.1-1.21.0
Bone: periosteal perimeter0.30.52.11.50.90.8-0.50.5-0.50.3-0.30.60.2-0.6
Bone: post-yield work0.00.00.2-0.0-0.0-0.0-0.50.2-0.20.3-0.2-0.00.20.1
Progressive ratio test 1 active lever presses1.81.94.62.21.71.7-1.41.3-1.21.1-1.21.00.9-1.1
Progressive ratio test 1 breakpoint1.71.84.22.01.61.6-1.41.3-1.21.1-1.20.90.9-1.0
Progressive ratio test 1 inactive lever presses1.71.82.71.61.51.5-1.51.4-1.31.3-1.31.01.2-1.2
Progressive ratio test 2 active lever presses0.50.62.91.71.21.2-0.30.5-0.30.1-0.30.2-0.1-0.3
Progressive ratio test 2 breakpoint0.70.83.81.91.41.3-0.40.6-0.40.1-0.40.3-0.1-0.4
Progressive ratio test 2 inactive lever presses0.60.74.52.11.21.2-0.30.4-0.1-0.2-0.20.2-0.4-0.2
Incentive Sensitization - Responses0.30.31.31.20.70.60.5-0.10.3-0.60.2-0.3-0.70.3
Incentive Sensitization - Breakpoint0.30.31.11.10.60.60.4-0.10.2-0.50.1-0.3-0.60.2
Sum of active levers in priming session hrs 5-60.80.71.2-0.5-0.8-0.81.0-0.91.1-1.00.9-0.8-1.00.8
Progressive ratio0.10.10.60.80.50.5-0.20.2-0.1-0.0-0.40.1-0.1-0.0
Food seeking constrained by brief footshock0.40.51.91.41.00.9-0.50.6-0.50.3-0.70.50.2-0.5
Seeking ratio, punishment vs. effort0.10.10.2-0.4-0.4-0.40.4-0.40.3-0.30.5-0.3-0.30.2
Retroperitoneal fat weight6.019.730.15.54.84.8-4.24.3-4.34.0-4.24.53.7-4.3
Reaction time number correct0.10.10.6-0.0-0.1-0.10.8-0.40.3-0.50.3-0.3-0.30.2
Reaction time mean minus median0.70.91.20.71.01.0-0.51.0-0.90.9-0.91.11.0-1.0
Reaction time mean minus median AUC0.20.30.50.60.70.7-0.10.5-0.50.4-0.40.70.5-0.7
Reaction time num false alarms0.71.01.9-1.4-1.2-1.20.6-0.80.7-0.61.3-1.1-0.71.0
Reaction time num false alarms AUC1.31.73.2-1.8-1.5-1.51.0-1.21.1-1.01.6-1.4-0.91.2
Reaction time trials correct on left0.10.10.6-0.0-0.1-0.10.8-0.40.3-0.50.3-0.3-0.30.2
Reaction time trials on left0.10.20.6-0.1-0.2-0.20.8-0.40.4-0.50.3-0.3-0.40.2
Reaction time mean0.10.20.30.60.50.5-0.40.5-0.40.4-0.40.40.4-0.3
Reaction time mean AUC0.10.20.50.70.50.5-0.30.4-0.30.3-0.40.40.2-0.3
Median of all reaction times0.20.30.60.80.60.6-0.60.6-0.50.5-0.50.50.4-0.3
Reaction time omissions0.20.31.0-1.0-0.7-0.70.5-0.40.4-0.30.5-0.6-0.20.5
Reaction time false alarm rate1.52.03.6-1.9-1.7-1.71.0-1.31.2-1.01.7-1.5-1.11.4
Reaction time premature initiation rate0.10.20.4-0.5-0.1-0.1-0.40.3-0.40.5-0.30.30.7-0.4
Reaction time premature initiations0.00.10.2-0.5-0.1-0.10.10.1-0.20.3-0.10.20.4-0.3
Std. dev. reaction times0.00.00.10.10.20.20.10.1-0.10.1-0.10.20.2-0.2
Reaction time trials completed0.10.20.6-0.1-0.2-0.20.8-0.40.4-0.50.3-0.3-0.40.2
Reaction time trials AUC0.00.10.40.10.00.00.6-0.20.2-0.30.1-0.1-0.20.0
Run reversals in cocaine runway, females0.10.10.40.30.20.2-0.60.2-0.30.2-0.10.10.2-0.1
Run reversals in cocaine runway, males2.62.54.1-2.0-1.8-1.81.8-1.61.6-1.41.3-1.5-1.21.2
Latency to leave start box in cocaine runway0.10.10.4-0.2-0.0-0.0-0.60.3-0.40.5-0.40.00.5-0.1
Latency to leave start box in cocaine runway, F0.70.81.40.10.50.5-1.20.9-1.01.1-1.00.61.2-0.7
Latency to leave start box in cocaine runway, M1.11.01.6-0.6-0.8-0.91.0-1.01.0-1.11.1-1.2-1.11.3
Std. dev. time between licks in bursts0.20.20.6-0.8-0.7-0.70.3-0.40.3-0.20.4-0.4-0.10.3
Total sessions with >9 infusions1.11.22.11.51.21.2-1.21.1-1.01.0-0.91.00.8-0.9
Short access day 1 total inactive lever presses1.21.41.70.91.11.1-1.31.2-1.21.3-1.21.11.3-1.2
Short access day 10 total inactive lever presses0.10.10.20.50.10.10.3-0.20.3-0.40.2-0.2-0.50.4
Short access day 1 total infusions3.23.58.02.82.32.3-1.71.8-1.61.4-1.51.71.2-1.5
Short access day 10 total infusions1.21.43.82.01.51.5-1.11.1-1.00.8-0.80.80.6-0.8
Short access total infusions2.12.44.92.21.91.9-1.61.6-1.41.3-1.21.31.1-1.2
Short access day 1 locomotion3.74.05.91.81.91.9-2.42.1-2.12.2-2.01.82.0-1.8
Short access day 10 total locomotion2.12.33.92.01.81.8-1.71.6-1.51.3-1.41.21.1-1.2
Short access total locomotion2.32.43.61.81.71.7-1.91.7-1.71.6-1.31.11.3-1.1
One hour access (0.3 mA shock)1.61.84.82.21.81.8-1.21.3-1.20.9-1.10.80.8-0.9
Compulsive drug intake0.40.41.2-1.1-0.8-0.70.6-0.60.5-0.40.3-0.6-0.10.4
One hour access (shock baseline)2.42.77.22.72.22.1-1.51.6-1.51.1-1.31.20.9-1.2
Social response proportion3.13.45.3-2.3-2.1-2.01.8-1.81.9-1.61.5-1.8-1.51.7
Social responses0.20.20.40.30.40.4-0.30.4-0.30.4-0.60.60.4-0.6
Social time1.52.03.4-1.9-1.4-1.41.8-1.41.5-1.31.0-1.2-1.11.1
Soleus weight1.03.04.1-1.9-2.0-2.01.5-1.71.7-1.51.5-1.8-1.51.7
Bone: stiffness0.20.40.80.90.60.6-0.90.6-0.60.6-0.40.50.4-0.5
Tibialis anterior weight2.99.911.3-3.2-3.4-3.33.1-3.23.1-3.03.3-3.1-2.93.1
Time to tail flick, vehicle, before self-admin1.41.45.42.31.71.6-0.30.8-0.40.3-0.81.30.2-1.1
Time to tail flick, vehicle, after self-admin2.52.74.82.22.12.0-1.41.6-1.51.3-1.61.61.2-1.4
Time to tail flick, test, before self-admin0.10.10.40.60.50.5-0.10.1-0.1-0.1-0.10.2-0.10.0
Time to tail flick, test, after self-admin0.50.52.01.41.01.0-0.40.5-0.50.3-0.40.60.2-0.5
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.10.10.1-0.50.3-0.50.3-0.2-0.10.20.1
Delta time to tail flick, test, before/after SA0.60.50.80.50.50.6-0.70.8-0.80.9-0.70.70.9-0.8
Tibia length0.41.21.6-0.7-1.0-1.01.3-1.21.2-1.21.3-1.1-1.21.0
Ambulatory time before self-admin0.20.20.50.70.0-0.00.3-0.30.4-0.60.4-0.4-0.70.4
Ambulatory time after self-admin0.10.10.40.70.30.3-0.10.0-0.1-0.1-0.20.1-0.2-0.0
Bone: tissue strength0.00.00.1-0.0-0.1-0.10.2-0.20.2-0.20.3-0.2-0.20.1
Total heroin consumption0.50.50.8-0.8-0.9-0.90.5-0.70.7-0.60.7-0.7-0.60.8
Bone: trabecular number0.30.40.90.90.70.7-0.70.7-0.60.6-0.50.50.4-0.3
Bone: trabecular spacing0.50.60.70.70.80.8-0.60.8-0.80.7-0.90.80.9-0.9
Bone: trabecular thickness0.10.10.30.60.30.3-0.20.2-0.20.2-0.20.10.1-0.1
Bone: trabecular tissue density1.21.72.1-1.2-1.3-1.31.4-1.41.5-1.41.2-1.2-1.31.1
Water consumed over 24 hours0.20.20.50.2-0.1-0.20.3-0.40.4-0.50.5-0.5-0.70.5
Number of responses in last shaping day0.20.21.21.10.50.40.2-0.10.3-0.50.3-0.0-0.60.3