Hub : Genes

Palm

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XM_039078326.1 0.1 0.08 1.9e-05 0.05 0.04 0.03 0.04 2.7e-05 1.3e-04 6.7e-04 1.1e-04
2 Adipose gene expression Palm 0.24 0.13 0.0e+00 0.18 0.19 0.19 0.19 1.1e-19 9.7e-21 2.0e-20 1.2e-20
3 LHb gene expression Palm 0.11 0.09 8.0e-03 0.05 0.04 0.02 0.04 2.9e-02 4.6e-02 9.9e-02 4.5e-02
4 pVTA gene expression Palm 0.27 0.16 2.1e-05 0.12 0.1 0.1 0.1 7.5e-06 3.3e-05 4.4e-05 2.7e-05
5 Liver gene expression Palm 0.07 0.05 2.9e-03 0.01 0.01 0.01 0.01 4.7e-02 6.6e-02 6.7e-03 4.1e-02
6 Adipose isoform ratio NM_130829.2 0.03 0.03 1.8e-03 0.02 0.02 0.02 0.02 4.2e-03 3.7e-03 4.5e-03 3.8e-03
7 NAcc mRNA stability Palm 0.06 0.05 9.2e-03 0.02 0.01 0.02 0.02 3.2e-03 2.6e-02 2.3e-03 5.1e-03
8 PL mRNA stability Palm 0.27 0.13 8.4e-12 0.11 0.12 0.12 0.12 7.7e-12 4.0e-13 5.3e-13 6.3e-13
9 Brain isoform ratio NM_130829.2 0.03 0.02 3.8e-03 0.01 0.01 0 0.01 3.2e-02 2.3e-02 9.4e-02 3.3e-02
10 Adipose mRNA stability Palm 0.39 0.17 0.0e+00 0.14 0.15 0.15 0.15 1.3e-15 5.4e-16 6.4e-16 4.5e-16
11 Brain mRNA stability Palm 0.24 0.12 7.1e-08 0.07 0.08 0.08 0.07 3.5e-07 1.3e-07 5.5e-08 4.5e-07
12 LHb mRNA stability Palm 0.6 0.19 4.6e-05 0.26 0.23 0.21 0.22 6.2e-07 4.3e-06 8.7e-06 7.1e-06
13 PL isoform ratio XM_039078327.1 0.14 0.09 8.7e-06 0.06 0.05 0.05 0.05 7.5e-07 2.3e-06 8.6e-06 3.1e-06
14 Brain intron excision ratio chr7_9888520_9892125 0.12 0.08 1.7e-03 0.02 0.02 0 0.01 7.4e-03 9.9e-03 1.2e-01 1.4e-02
15 PL intron excision ratio chr7_9890662_9892125 0.07 0.05 9.5e-03 0.03 0.02 0.02 0.02 3.6e-04 1.1e-03 1.8e-03 9.1e-04
16 NAcc intron excision ratio chr7_9888520_9892125 0.12 0.08 8.5e-05 0.04 0.03 0.04 0.04 5.9e-06 1.7e-04 2.8e-05 3.4e-05
17 pVTA mRNA stability Palm 0.2 0.13 2.2e-03 0.08 0.06 0.07 0.07 2.2e-04 1.0e-03 6.5e-04 3.7e-04
18 NAcc intron excision ratio chr7_9890662_9892125 0.07 0.05 8.5e-03 0.02 0.01 0.02 0.01 1.3e-03 2.7e-02 5.3e-03 6.7e-03
19 NAcc isoform ratio XM_039078327.1 0.1 0.07 1.9e-04 0.04 0.03 0.03 0.03 4.4e-05 1.1e-04 1.9e-04 2.8e-04
20 PL intron excision ratio chr7_9888520_9892125 0.12 0.08 4.0e-04 0.04 0.04 0.04 0.04 2.4e-05 6.3e-05 5.4e-05 3.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density2.74.67.40.9-0.3-0.9-0.9-1.4-0.1-2.62.7-0.72.3-2.5-2.4-2.4-2.62.7-2.7-2.72.7-2.6-2.6
Area under the delay curve0.91.02.7-1.61.61.61.61.21.70.7-0.5-1.7-0.60.40.20.20.2-0.30.30.3-0.30.30.3
BMI with tail2.89.024.1-4.74.94.74.73.84.92.2-2.3-4.7-2.21.81.21.21.3-1.01.11.1-1.11.01.0
BMI without tail2.45.08.7-2.92.63.03.02.72.52.6-2.3-2.0-2.42.02.02.01.7-1.71.71.7-1.71.61.6
Body weight0.62.46.0-2.42.42.42.41.92.41.4-1.3-2.2-1.21.00.70.70.8-0.70.70.7-0.70.60.6
Weight adjusted by age1.92.22.9-1.21.11.31.31.61.01.7-1.7-0.6-1.71.51.61.61.5-1.61.61.6-1.61.51.5
Bone surface5.39.414.51.9-1.2-1.9-1.9-2.6-0.9-3.83.8-0.13.4-3.6-3.5-3.5-3.63.6-3.6-3.63.6-3.6-3.6
Bone volume5.28.813.71.7-1.0-1.7-1.7-2.4-0.8-3.73.7-0.33.3-3.5-3.4-3.4-3.53.6-3.5-3.53.5-3.5-3.5
Breakpoint value in progressive ratio session1.61.86.92.1-2.4-2.1-2.1-1.3-2.4-0.20.22.60.20.00.40.40.3-0.40.40.4-0.40.30.3
Number of licking bursts1.61.93.3-0.80.60.70.71.10.51.4-1.5-0.0-1.41.61.31.31.5-1.71.81.8-1.81.81.8
Context. condit. distance diff. score0.30.30.9-0.70.40.70.70.50.30.9-0.6-0.2-0.50.50.50.50.5-0.50.60.6-0.60.50.5
Locomotion velocity, session 11.92.03.01.3-1.0-1.3-1.3-1.5-0.9-1.71.70.51.6-1.6-1.5-1.5-1.51.6-1.5-1.51.5-1.6-1.6
Locomotion distance, session 14.66.09.11.4-1.3-1.4-1.4-2.5-1.1-2.62.80.32.9-2.8-2.8-2.8-2.83.0-2.9-2.92.9-2.9-2.9
Locomotion velocity, session 26.77.812.53.0-3.0-3.0-3.0-3.5-2.8-2.83.02.13.1-2.9-2.6-2.6-2.62.6-2.6-2.62.6-2.6-2.6
Locomotion distance, session 26.28.612.12.5-2.1-2.5-2.5-3.1-1.9-3.53.31.13.3-3.1-3.1-3.1-3.13.3-3.3-3.33.3-3.1-3.1
Locomotion velocity, session 32.12.59.22.5-2.8-2.5-2.5-1.9-2.9-0.50.43.00.6-0.20.10.10.1-0.10.20.2-0.20.20.2
Locomotion distance, session 30.20.20.4-0.20.00.20.20.3-0.00.5-0.60.2-0.50.60.50.50.5-0.30.40.4-0.40.60.6
Stereotopy head waving bouts, day 33.33.88.72.8-3.0-2.9-2.9-2.8-2.9-1.81.62.71.9-1.3-1.3-1.3-1.20.8-0.9-0.90.9-1.0-1.0
Stereotopy head waving duration, day 32.93.59.32.9-3.0-2.9-2.9-2.6-3.1-1.41.32.91.5-1.0-0.9-0.9-0.80.4-0.4-0.40.4-0.6-0.6
Locomotion velocity, session 70.30.31.00.4-0.9-0.3-0.3-0.5-0.90.6-0.31.0-0.10.40.40.40.3-0.40.50.5-0.50.40.4
Locomotion distance, session 71.31.62.6-1.00.71.01.01.20.61.6-1.5-0.2-1.41.51.51.51.4-1.31.41.4-1.41.41.4
Stereotopy head waving bouts, day 71.21.31.90.7-0.6-0.7-0.7-1.2-0.5-1.31.20.11.4-1.3-1.3-1.3-1.31.4-1.3-1.31.3-1.4-1.4
Stereotopy head waving duration, day 71.62.02.71.1-0.9-1.1-1.1-1.5-0.8-1.61.60.41.6-1.6-1.6-1.6-1.51.6-1.5-1.51.5-1.6-1.6
Locomotion velocity, session 83.23.86.21.6-1.5-1.6-1.6-2.5-1.4-2.12.10.82.4-2.1-2.2-2.2-2.22.1-1.9-1.91.9-2.0-2.0
Locomotion distance, session 80.81.21.80.9-1.0-0.9-0.9-1.4-0.9-1.01.20.61.3-1.2-1.1-1.1-1.11.3-1.2-1.21.2-1.2-1.2
Degree of sensitization distance0.20.20.5-0.70.60.70.70.30.60.5-0.2-0.6-0.20.20.10.10.0-0.30.30.3-0.30.10.1
Degree of sensitization stereotypy0.80.82.3-1.01.21.01.00.41.3-0.50.4-1.50.4-0.6-0.7-0.7-0.71.0-1.0-1.01.0-0.9-0.9
Conditioned locomotion2.32.73.8-1.91.71.91.92.01.61.8-1.9-1.1-1.81.71.61.61.6-1.41.41.4-1.41.51.5
Cocaine response after cond. corrected7.07.911.9-3.43.13.33.33.43.03.2-2.9-2.3-2.92.72.42.42.5-2.52.52.5-2.52.42.4
Cocaine response after cond. not corrected7.58.312.5-3.43.13.43.43.53.03.3-3.0-2.3-3.12.92.52.52.6-2.52.52.5-2.52.52.5
Cocaine response before conditioning0.30.40.90.9-1.0-0.8-0.8-0.9-1.0-0.60.40.90.6-0.3-0.3-0.3-0.40.5-0.6-0.60.6-0.4-0.4
Saline control response0.00.10.1-0.30.30.30.30.30.30.1-0.3-0.2-0.20.30.20.20.3-0.0-0.1-0.10.10.10.1
Bone: connectivity density1.62.54.30.40.1-0.3-0.3-0.80.3-1.82.0-0.91.6-1.9-1.8-1.8-2.12.0-2.1-2.12.1-1.9-1.9
Bone: cortical apparent density0.40.61.7-1.01.31.01.01.01.30.3-0.4-1.2-0.50.50.10.10.2-0.50.50.5-0.50.50.5
Bone: cortical area0.30.51.1-0.50.70.60.6-0.10.8-0.60.6-1.10.6-0.6-0.8-0.8-0.80.7-0.7-0.70.7-0.8-0.8
Bone: cortical porosity1.01.11.51.0-0.9-1.0-1.0-1.2-0.8-1.21.10.61.2-1.1-1.0-1.0-0.91.2-1.2-1.21.2-1.1-1.1
Bone: cortical porosity1.61.72.80.7-0.5-0.8-0.8-1.2-0.4-1.61.4-0.01.5-1.4-1.5-1.5-1.41.6-1.7-1.71.7-1.5-1.5
Bone: cortical thickness0.40.62.4-1.11.31.11.10.61.4-0.20.2-1.50.1-0.2-0.5-0.5-0.50.4-0.5-0.50.5-0.4-0.4
Bone: cortical thickness1.11.32.0-0.70.50.70.71.10.41.3-1.40.0-1.41.41.31.31.4-1.31.21.2-1.21.31.3
Bone: cortical tissue density0.30.51.3-0.81.10.80.80.91.10.3-0.4-1.0-0.50.50.20.20.2-0.50.60.6-0.60.50.5
Condit. Reinf. active minus inactive responses1.82.06.32.3-2.5-2.2-2.2-1.8-2.5-0.70.82.50.9-0.6-0.4-0.4-0.30.3-0.3-0.30.3-0.4-0.4
Condit. Reinf. active-inactive response ratio0.70.82.81.2-1.3-1.1-1.1-0.3-1.40.4-0.31.7-0.40.50.70.70.8-0.70.60.6-0.60.70.7
Condit. Reinf. active responses3.64.47.32.6-2.7-2.7-2.7-2.7-2.6-2.02.02.22.1-1.9-1.6-1.6-1.51.6-1.6-1.61.6-1.7-1.7
Condit. Reinf. inactive responses3.74.45.91.7-1.6-1.8-1.8-2.3-1.5-2.42.30.92.4-2.3-2.1-2.1-2.12.3-2.2-2.22.2-2.4-2.4
Incentive salience index mean2.32.84.92.1-2.2-2.0-2.0-2.2-2.2-1.51.61.91.7-1.5-1.3-1.3-1.21.3-1.3-1.31.3-1.4-1.4
Condit. Reinf. lever presses3.75.07.91.1-0.8-1.1-1.1-2.0-0.6-2.52.5-0.12.5-2.6-2.5-2.5-2.62.8-2.8-2.82.8-2.8-2.8
Condit. Reinf. active minus inactive responses0.81.02.60.9-1.1-1.0-1.0-0.1-1.20.3-0.81.6-0.70.91.01.01.1-1.01.11.1-1.11.01.0
Condit. Reinf. active-inactive response ratio1.01.11.9-0.40.50.30.31.20.40.8-1.20.1-1.31.21.31.31.4-1.21.31.3-1.31.11.1
Condit. Reinf. active responses0.60.82.71.1-1.3-1.2-1.2-0.5-1.4-0.1-0.41.6-0.30.50.60.60.7-0.80.70.7-0.70.70.7
Condit. Reinf. inactive responses0.30.41.60.9-1.2-0.9-0.9-0.8-1.2-0.1-0.11.30.10.20.10.10.2-0.50.30.3-0.30.40.4
Condit. Reinf. lever presses0.60.83.21.2-1.4-1.2-1.2-0.4-1.50.1-0.41.8-0.40.50.90.90.9-0.70.50.5-0.50.60.6
Condit. Reinf. lever reinforcers received0.60.92.00.8-1.0-0.8-0.8-0.0-1.10.4-0.81.4-0.70.91.01.01.0-1.11.01.0-1.01.01.0
Conditioned reinforcement - actives0.80.82.11.4-1.5-1.4-1.4-1.0-1.5-0.60.71.40.5-0.6-0.1-0.1-0.40.4-0.4-0.40.4-0.4-0.4
Conditioned reinforcement - inactives0.60.71.3-1.10.81.11.11.10.81.0-0.9-0.6-1.00.70.90.90.6-0.60.60.6-0.60.60.6
Conditioned locomotion2.53.08.82.8-2.9-2.8-2.8-2.0-3.0-1.11.12.91.0-0.9-0.2-0.2-0.50.5-0.5-0.50.5-0.5-0.5
Patch foraging indifference point 0 sec0.10.10.3-0.30.40.20.20.00.5-0.30.3-0.60.2-0.3-0.4-0.4-0.40.4-0.5-0.50.5-0.4-0.4
Patch foraging indifference point AUC0.20.20.80.8-0.8-0.8-0.8-0.5-0.8-0.30.20.90.2-0.00.00.00.10.00.00.0-0.0-0.0-0.0
Delay disc. indifference point, 0s delay3.43.89.6-1.72.21.71.70.42.4-1.31.4-3.11.2-1.8-1.9-1.9-2.12.1-2.1-2.12.1-2.1-2.1
Delay disc. indifference point, 16s delay0.10.10.1-0.30.40.30.30.40.40.3-0.1-0.3-0.30.10.10.10.1-0.30.30.3-0.30.30.3
Delay disc. indifference point, 2s delay1.61.87.1-2.12.32.12.11.12.40.0-0.1-2.7-0.0-0.2-0.6-0.6-0.50.5-0.6-0.60.6-0.5-0.5
Delay disc. indifference point, 24s delay0.70.71.3-1.11.11.11.11.11.10.8-0.7-1.0-0.80.60.50.50.5-0.60.70.7-0.70.60.6
Delay disc. indifference point, 4s delay0.20.31.1-0.80.90.80.80.40.90.00.1-1.0-0.0-0.2-0.2-0.2-0.30.2-0.1-0.10.1-0.2-0.2
Delay disc. indifference point, 8s delay1.51.52.6-1.61.41.61.61.51.41.4-1.2-1.2-1.21.11.01.00.9-1.11.01.0-1.01.01.0
Indifference point function ln k0.30.40.7-0.80.70.80.80.80.70.7-0.7-0.5-0.70.60.60.60.5-0.50.50.5-0.50.50.5
Indifference point function log k0.30.40.7-0.80.70.80.80.80.70.7-0.7-0.5-0.70.60.60.60.5-0.50.50.5-0.50.50.5
Patch foraging total patch changes 0 sec0.00.10.2-0.40.40.30.30.10.4-0.10.0-0.50.1-0.1-0.2-0.2-0.10.1-0.2-0.20.2-0.1-0.1
Patch foraging total patch changes 12 sec0.40.60.9-0.90.80.90.90.90.80.9-0.8-0.6-0.80.80.70.70.7-0.60.50.5-0.50.60.6
Patch foraging total patch changes 18 sec0.40.51.51.1-1.2-1.2-1.2-0.9-1.2-0.60.41.20.5-0.3-0.2-0.2-0.10.2-0.4-0.40.4-0.2-0.2
Patch foraging total patch changes 24 sec0.10.10.30.4-0.2-0.4-0.4-0.3-0.2-0.50.40.10.3-0.3-0.3-0.3-0.30.3-0.4-0.40.4-0.3-0.3
Patch foraging total patch changes 6 sec0.10.20.50.7-0.5-0.7-0.7-0.6-0.4-0.70.50.40.5-0.3-0.5-0.5-0.30.2-0.2-0.20.2-0.2-0.2
Patch foraging time to switch 0 sec1.62.54.1-0.20.50.20.2-0.90.6-1.51.8-1.31.8-1.9-2.0-2.0-2.01.9-1.9-1.91.9-1.9-1.9
Patch foraging water rate 0 sec2.43.96.4-1.10.71.11.11.70.52.3-2.50.2-2.32.42.32.32.4-2.32.22.2-2.22.32.3
Patch foraging water rate 12 sec3.45.27.3-2.21.92.22.22.61.82.6-2.7-1.1-2.62.52.32.32.3-2.32.32.3-2.32.32.3
Patch foraging water rate 18 sec5.67.611.1-1.30.81.31.32.40.53.2-3.30.5-3.23.33.33.33.3-3.33.33.3-3.33.23.2
Patch foraging water rate 24 sec5.47.611.6-2.01.52.02.02.81.33.3-3.4-0.3-3.33.23.23.23.2-3.12.92.9-2.93.13.1
Patch foraging water rate 6 sec2.13.14.9-0.60.10.60.61.4-0.02.1-2.10.7-2.12.12.22.22.2-2.12.12.1-2.12.12.1
Seeking ratio, delayed vs. immediate footshock2.02.35.82.4-2.4-2.4-2.4-2.0-2.4-1.41.22.21.3-0.9-0.8-0.8-0.70.6-0.6-0.60.6-0.4-0.4
Distance traveled before self-admin0.20.20.8-0.50.70.50.50.20.7-0.30.4-0.90.3-0.3-0.6-0.6-0.40.2-0.2-0.20.2-0.4-0.4
Distance traveled after self-admin0.40.40.80.9-0.9-0.9-0.9-0.8-0.8-0.70.70.70.7-0.6-0.6-0.6-0.50.4-0.4-0.40.4-0.5-0.5
Extensor digitorum longus weight2.811.124.0-4.94.64.94.94.04.53.4-3.2-4.0-3.02.62.12.12.2-2.12.02.0-2.02.02.0
Bone: elastic displacement0.10.10.30.3-0.3-0.5-0.5-0.2-0.3-0.50.30.20.3-0.2-0.3-0.3-0.10.3-0.3-0.30.3-0.3-0.3
Bone: elastic work0.10.10.5-0.70.70.50.50.40.7-0.0-0.0-0.7-0.00.1-0.2-0.20.10.1-0.1-0.10.1-0.1-0.1
Bone: endosteal estimation0.00.10.4-0.60.40.40.40.10.50.1-0.2-0.50.10.1-0.3-0.30.1-0.20.30.3-0.3-0.1-0.1
Bone: endosteal perimeter0.30.71.21.0-1.0-0.9-0.9-1.1-0.9-0.80.90.70.9-0.9-0.7-0.7-0.80.7-0.6-0.60.6-1.0-1.0
Epididymis fat weight0.10.20.80.6-0.8-0.7-0.7-0.3-0.8-0.00.00.9-0.10.00.30.30.2-0.20.30.3-0.30.20.2
Delta time in closed arm before/after self-admin5.04.86.7-1.81.41.81.82.31.32.6-2.6-0.6-2.62.52.42.42.4-2.32.32.3-2.32.42.4
Delta time in open arm before/after self-admin0.40.31.5-0.81.00.80.80.51.1-0.10.2-1.20.2-0.3-0.4-0.4-0.40.2-0.2-0.20.2-0.4-0.4
Diff in mean of infusions in LGA sessions0.80.82.51.5-1.6-1.5-1.5-1.1-1.6-0.50.51.60.6-0.4-0.2-0.2-0.2-0.00.00.0-0.0-0.2-0.2
Delay discount exponential model param0.91.02.61.6-1.6-1.6-1.6-1.2-1.6-0.80.61.60.7-0.5-0.3-0.3-0.30.4-0.5-0.50.5-0.4-0.4
Extinction: sum of active levers before priming0.50.51.50.6-0.9-0.6-0.6-0.1-1.00.5-0.41.2-0.40.60.70.70.7-0.60.60.6-0.60.70.7
Active lever presses in extinction session 61.21.22.71.6-1.6-1.6-1.6-1.2-1.6-1.01.01.50.9-0.8-0.6-0.6-0.60.6-0.6-0.60.6-0.6-0.6
Bone: final force0.40.62.4-1.41.31.21.20.51.40.0-0.1-1.50.2-0.0-0.5-0.5-0.20.2-0.2-0.20.2-0.2-0.2
Bone: final moment0.30.51.9-1.21.21.01.00.41.2-0.0-0.0-1.40.2-0.0-0.5-0.5-0.20.1-0.1-0.10.1-0.2-0.2
Food consumed during 24 hour testing period0.91.01.7-1.11.01.01.00.91.01.0-0.9-0.8-0.81.00.50.50.7-1.31.31.3-1.31.21.2
Glucose0.71.12.9-1.51.71.51.51.41.70.6-0.8-1.6-0.80.60.40.40.4-0.50.50.5-0.50.40.4
Heart weight0.20.30.80.3-0.2-0.2-0.20.5-0.30.5-0.50.5-0.80.50.90.90.6-0.60.60.6-0.60.60.6
Delay discount hyperbolic model param1.21.23.51.8-1.9-1.8-1.8-1.3-1.9-0.80.61.90.7-0.4-0.2-0.2-0.20.3-0.3-0.30.3-0.3-0.3
Intermittent access intake day 1-15 change1.91.97.32.2-2.5-2.2-2.2-1.5-2.6-0.50.42.70.4-0.30.20.20.1-0.00.00.0-0.00.00.0
Intermittent access intake escalation1.81.87.11.7-2.2-1.7-1.7-0.9-2.30.4-0.52.7-0.40.61.11.10.9-0.80.80.8-0.80.80.8
Intermittent access intake escalation 22.12.08.42.0-2.4-2.0-2.0-1.0-2.50.3-0.42.9-0.30.51.01.00.9-0.80.80.8-0.80.80.8
Intermitt. access day 1 inactive lever presses0.60.61.2-0.3-0.00.30.30.6-0.11.0-0.90.4-1.00.81.11.10.8-0.90.90.9-0.90.90.9
Intermitt. access day 15 inactive lever presses0.20.20.70.5-0.7-0.5-0.5-0.2-0.70.2-0.20.8-0.20.10.40.40.2-0.30.30.3-0.30.30.3
Intermitt. access escalation Index0.70.61.20.10.2-0.1-0.1-0.60.2-1.00.9-0.50.9-0.8-1.1-1.1-0.90.8-0.8-0.80.8-0.8-0.8
Intermittent access day 1 total infusions0.00.00.1-0.20.20.20.20.20.2-0.10.2-0.3-0.0-0.2-0.0-0.0-0.30.2-0.2-0.20.2-0.2-0.2
Intermittent access day 15 total infusions0.50.62.51.0-1.3-1.0-1.0-0.4-1.40.2-0.11.6-0.30.10.70.70.3-0.40.40.4-0.40.40.4
Intermittent access terminal intake (last 3 days)0.30.31.10.8-1.0-0.8-0.8-0.5-1.0-0.10.21.10.0-0.30.30.3-0.20.1-0.1-0.10.1-0.1-0.1
Intermittent access total infusions0.10.10.20.2-0.4-0.2-0.20.0-0.40.2-0.10.5-0.30.00.40.40.1-0.20.20.2-0.20.20.2
Intermittent access day 1 locomotion0.10.10.50.5-0.6-0.5-0.5-0.2-0.70.00.00.7-0.10.00.30.30.1-0.20.20.2-0.20.20.2
Intermittent access day 15 total locomotion1.21.34.31.8-2.0-1.8-1.8-1.2-2.0-0.60.62.10.4-0.40.10.1-0.10.0-0.0-0.00.0-0.0-0.0
Intermittent access total locomotion0.40.41.21.0-1.1-1.0-1.0-0.7-1.1-0.60.61.00.4-0.5-0.1-0.1-0.30.3-0.3-0.30.3-0.3-0.3
Intermittent access standard deviation0.70.83.11.2-1.4-1.2-1.2-0.5-1.50.3-0.31.8-0.30.40.70.70.6-0.60.60.6-0.60.60.6
Left kidney weight0.10.30.90.6-0.4-0.5-0.5-0.8-0.3-0.70.70.10.9-0.5-1.0-1.0-0.60.4-0.4-0.40.4-0.4-0.4
Right kidney weight0.51.44.11.9-2.0-2.0-2.0-1.6-2.0-0.70.72.00.9-0.4-0.5-0.5-0.1-0.00.10.1-0.10.00.0
Cocaine induced anxiety1.92.23.11.3-1.1-1.3-1.3-1.6-1.0-1.81.70.51.7-1.7-1.6-1.6-1.61.6-1.6-1.61.6-1.6-1.6
Post-drug Anxiety1.82.02.71.3-1.1-1.3-1.3-1.5-1.0-1.61.60.61.6-1.6-1.5-1.5-1.51.5-1.5-1.51.5-1.5-1.5
Baseline Anxiety0.60.71.1-0.0-0.20.00.00.5-0.30.9-0.90.6-0.91.01.01.01.0-1.01.01.0-1.01.01.0
Tail length0.92.710.82.6-3.1-2.5-2.5-1.8-3.1-0.10.43.30.3-0.10.50.50.2-0.40.40.4-0.40.30.3
Length with tail0.83.07.72.7-2.8-2.6-2.6-2.3-2.8-1.21.32.61.4-1.1-0.8-0.8-0.70.8-0.9-0.90.9-0.8-0.8
Length without tail0.71.62.50.9-0.6-0.9-0.9-1.3-0.5-1.61.40.21.6-1.3-1.5-1.5-1.21.4-1.5-1.51.5-1.5-1.5
Times rat made contact with spout1.41.73.1-0.90.80.90.91.10.71.3-1.3-0.3-1.21.41.11.11.1-1.71.71.7-1.71.71.7
Lifetime Intake0.00.00.10.1-0.3-0.1-0.1-0.0-0.30.10.10.3-0.1-0.10.20.2-0.10.0-0.0-0.00.0-0.0-0.0
Liver weight, left1.01.64.0-1.91.92.02.01.61.91.1-1.0-1.8-1.00.80.60.60.6-0.50.50.5-0.50.50.5
Liver weight, right0.40.72.5-1.41.41.41.40.71.40.3-0.2-1.6-0.1-0.0-0.3-0.3-0.20.2-0.1-0.10.1-0.1-0.1
Locomotor activity2.84.46.92.5-2.5-2.6-2.6-2.6-2.4-2.22.22.02.2-2.1-1.7-1.7-1.81.6-1.7-1.71.7-1.7-1.7
Locomotor testing distance1.42.33.91.9-1.9-2.0-2.0-1.8-1.8-1.51.61.51.4-1.4-1.1-1.1-1.21.2-1.2-1.21.2-1.2-1.2
Locomotor testing rearing0.30.40.8-0.30.10.30.30.60.10.8-0.80.2-0.80.70.90.90.8-0.70.60.6-0.60.70.7
Locomotion in novel chamber0.40.51.20.1-0.2-0.2-0.20.1-0.20.4-0.60.4-0.40.70.40.40.7-1.11.11.1-1.11.01.0
Locomotion in novel chamber post-restriction0.40.51.50.7-0.9-0.6-0.6-0.4-1.00.5-0.51.2-0.30.50.60.60.6-0.70.70.7-0.70.70.7
Fecal boli incidents, locomotor time 10.91.02.5-1.61.41.61.61.21.40.9-0.8-1.4-0.80.70.50.50.5-0.50.50.5-0.50.50.5
Change in fecal boli incidents, locomotor task0.10.10.30.4-0.4-0.4-0.4-0.5-0.4-0.30.30.30.4-0.4-0.4-0.4-0.40.3-0.3-0.30.3-0.3-0.3
Time >=10cm from walls, locomotor time 10.80.81.4-0.40.60.40.4-0.30.7-0.81.0-1.10.9-1.1-1.2-1.2-1.20.9-0.9-0.90.9-1.1-1.1
Bouts of movement, locomotor time 10.20.20.40.2-0.5-0.2-0.2-0.3-0.50.4-0.30.6-0.20.30.30.30.3-0.50.50.5-0.50.50.5
Total resting periods, locomotor time 10.10.10.50.4-0.6-0.4-0.4-0.5-0.60.2-0.10.70.00.10.20.20.2-0.30.30.3-0.30.30.3
Rest time, locomotor task time 10.30.41.20.7-1.0-0.7-0.7-1.1-1.0-0.40.50.80.6-0.5-0.4-0.4-0.40.3-0.3-0.30.3-0.4-0.4
Distance moved, locomotor task time 10.70.81.4-0.30.80.30.30.00.9-0.90.9-1.20.7-0.9-1.0-1.0-1.01.0-1.0-1.01.0-1.0-1.0
Vertical activity count, locomotor time 10.91.02.1-0.91.00.90.91.41.01.0-1.0-0.7-1.11.01.01.01.0-1.01.01.0-1.01.01.0
Time >=10cm from walls, locomotor time 21.31.42.8-1.71.61.71.71.41.51.2-1.0-1.4-1.00.90.70.70.7-0.90.90.9-0.90.70.7
Bouts of movement, locomotor time 21.61.72.51.3-1.1-1.3-1.3-1.5-1.0-1.51.60.61.5-1.5-1.4-1.4-1.41.2-1.2-1.21.2-1.2-1.2
Total resting periods, locomotor time 21.61.72.61.3-1.0-1.3-1.3-1.5-1.0-1.61.60.61.6-1.5-1.5-1.5-1.51.2-1.2-1.21.2-1.2-1.2
Rest time, locomotor task time 20.70.81.61.1-1.0-1.1-1.1-1.3-1.0-1.01.00.81.0-1.0-0.9-0.9-0.90.6-0.6-0.60.6-0.7-0.7
Distance moved, locomotor task time 20.50.61.2-1.11.11.11.11.01.00.8-0.8-0.9-0.80.70.60.60.6-0.40.40.4-0.40.40.4
Vertical activity count, locomotor time 21.61.82.7-1.51.21.51.51.71.11.6-1.5-0.8-1.51.51.41.41.4-1.21.21.2-1.21.21.2
Light reinforcement 13.66.614.93.9-3.7-3.7-3.7-3.0-3.7-2.42.33.32.1-2.0-1.4-1.4-1.51.7-1.6-1.61.6-1.7-1.7
Light reinforcement 21.62.14.42.1-1.8-2.0-2.0-1.6-1.8-1.51.41.61.2-1.3-0.8-0.8-1.01.2-1.2-1.21.2-1.2-1.2
Bone: marrow area0.00.10.4-0.60.40.40.40.10.50.1-0.2-0.50.10.1-0.3-0.30.1-0.30.30.3-0.3-0.1-0.1
Bone: maximum diameter1.01.93.01.6-1.4-1.5-1.5-1.7-1.4-1.51.51.01.5-1.4-1.3-1.3-1.31.1-1.1-1.11.1-1.4-1.4
Bone: maximum force0.40.72.5-1.61.41.31.30.81.50.4-0.4-1.5-0.20.4-0.1-0.10.2-0.20.20.2-0.20.10.1
Bone: maximum moment0.30.62.0-1.41.31.21.20.71.30.3-0.4-1.4-0.20.3-0.2-0.20.2-0.20.20.2-0.20.10.1
Mean time between licks in bursts1.31.86.42.2-2.3-2.2-2.2-1.4-2.4-0.60.32.50.4-0.10.20.20.2-0.30.20.2-0.20.30.3
Mean num. licks in bursts0.00.10.10.10.0-0.0-0.0-0.10.1-0.20.3-0.20.2-0.3-0.3-0.3-0.40.3-0.3-0.30.3-0.3-0.3
Cd content in liver0.10.20.5-0.40.60.40.40.30.6-0.40.0-0.70.1-0.2-0.2-0.2-0.20.3-0.5-0.50.5-0.3-0.3
Co content in liver0.20.20.80.7-0.8-0.6-0.6-0.5-0.8-0.2-0.00.90.10.00.20.20.1-0.0-0.1-0.10.10.00.0
Cu content in liver0.80.91.50.1-0.0-0.1-0.1-0.70.1-1.21.1-0.41.1-1.2-1.2-1.2-1.21.2-1.2-1.21.2-1.2-1.2
Fe content in liver0.10.10.3-0.0-0.30.10.1-0.0-0.40.5-0.50.5-0.30.40.50.50.5-0.30.20.2-0.20.30.3
K content in liver1.61.62.50.6-0.5-0.5-0.5-1.5-0.5-1.41.3-0.01.6-1.4-1.5-1.5-1.51.5-1.5-1.51.5-1.5-1.5
Mg content in liver1.51.62.30.6-0.4-0.5-0.5-1.3-0.3-1.51.4-0.21.5-1.4-1.5-1.5-1.51.5-1.5-1.51.5-1.5-1.5
Mn content in liver4.44.97.11.8-1.7-1.8-1.8-2.6-1.6-2.42.50.92.7-2.4-2.4-2.4-2.42.4-2.3-2.32.3-2.4-2.4
Na content in liver1.31.42.4-0.40.30.40.4-0.70.4-1.01.0-0.91.3-1.2-1.3-1.3-1.41.6-1.5-1.51.5-1.6-1.6
Rb content in liver0.91.21.90.00.20.00.0-0.70.3-1.21.2-0.81.2-1.3-1.4-1.4-1.41.3-1.2-1.21.2-1.3-1.3
Se content in liver0.30.30.80.6-0.9-0.6-0.6-0.9-0.9-0.30.40.70.6-0.4-0.4-0.4-0.40.4-0.5-0.50.5-0.4-0.4
Sr content in liver1.00.91.4-0.40.20.40.40.80.11.1-1.10.2-1.11.11.21.21.2-1.21.21.2-1.21.21.2
Zn content in liver1.82.03.10.6-0.8-0.5-0.50.5-0.91.4-1.41.5-1.41.61.81.81.8-1.81.71.7-1.71.81.8
Bone: minimum diameter0.10.10.40.1-0.2-0.1-0.1-0.6-0.2-0.30.30.00.6-0.3-0.6-0.6-0.40.3-0.3-0.30.3-0.5-0.5
Time in familiar zone, hab. session 10.80.82.51.1-1.3-1.1-1.1-0.3-1.30.5-0.31.6-0.50.60.80.80.7-0.70.80.8-0.80.70.7
Time in novel zone, hab. session 10.80.81.4-0.60.80.60.6-0.10.9-0.80.7-1.20.8-0.9-1.1-1.1-1.01.0-1.1-1.11.1-1.0-1.0
Total zone transitions, hab. session 13.04.35.91.9-1.7-1.9-1.9-2.4-1.6-2.32.31.02.4-2.2-2.2-2.2-2.22.2-2.2-2.22.2-2.0-2.0
Total locomotion distance, hab. session 14.76.79.62.1-2.0-2.2-2.2-3.1-1.9-2.92.81.13.1-2.7-2.8-2.8-2.82.8-2.8-2.82.8-2.6-2.6
Locomotion velocity, hab. session 14.76.610.42.3-2.3-2.4-2.4-3.2-2.2-2.82.81.43.0-2.7-2.7-2.7-2.72.6-2.7-2.72.7-2.5-2.5
Time in familiar zone, hab. session 22.02.17.62.1-2.3-2.1-2.1-0.8-2.40.2-0.22.8-0.50.61.11.11.0-1.00.90.9-0.91.11.1
Time in novel zone, hab. session 21.41.45.8-1.82.01.81.80.72.1-0.10.2-2.40.3-0.5-0.9-0.9-0.80.6-0.4-0.40.4-0.6-0.6
Total zone transitions, hab. session 24.25.49.10.9-0.5-0.9-0.9-2.1-0.3-2.72.7-0.52.8-2.9-3.0-3.0-3.02.8-2.6-2.62.6-2.6-2.6
Total locomotion distance, hab. session 23.54.76.72.0-1.8-2.0-2.0-2.6-1.7-2.42.61.02.5-2.5-2.4-2.4-2.42.1-2.0-2.02.0-2.1-2.1
Locomotion velocity, hab. session 24.76.49.22.2-1.9-2.2-2.2-3.0-1.7-2.93.00.93.0-2.9-2.9-2.9-3.02.5-2.4-2.42.4-2.5-2.5
Novel to familiar place preference ratio1.92.05.6-1.51.81.51.50.41.9-0.70.7-2.40.8-1.0-1.3-1.3-1.31.4-1.4-1.41.4-1.4-1.4
Novelty place preference1.41.43.4-1.01.31.11.10.11.5-0.70.8-1.80.8-1.0-1.3-1.3-1.31.3-1.3-1.31.3-1.3-1.3
Time in novel zone, NPP test1.21.33.7-1.21.51.21.20.31.6-0.50.6-1.90.6-0.8-1.1-1.1-1.11.1-1.1-1.11.1-1.1-1.1
Total zone transitions, NPP test2.53.55.21.0-0.6-1.0-1.0-1.7-0.4-2.22.1-0.22.2-2.2-2.2-2.2-2.22.3-2.3-2.32.3-2.2-2.2
Total locomotion distance, NPP test2.43.34.90.8-0.6-0.8-0.8-1.7-0.5-2.02.0-0.12.1-2.1-2.2-2.2-2.22.2-2.2-2.22.2-2.1-2.1
Locomotion velocity, NPP test2.63.65.11.1-0.8-1.1-1.1-1.9-0.7-2.22.20.12.2-2.2-2.2-2.2-2.22.3-2.3-2.32.3-2.2-2.2
Intraocular pressure1.82.64.1-0.70.60.70.71.70.51.9-1.80.1-2.01.92.02.02.0-1.71.81.8-1.81.91.9
Delta distance traveled before/after self-admin0.70.82.31.4-1.5-1.4-1.4-1.1-1.5-0.60.51.50.6-0.5-0.2-0.2-0.30.4-0.4-0.40.4-0.3-0.3
Delta ambulatory time before/after self-admin1.01.12.71.5-1.6-1.5-1.5-1.4-1.7-0.80.71.60.8-0.7-0.4-0.4-0.50.6-0.6-0.60.6-0.5-0.5
Parametrial fat weight0.10.30.90.5-0.7-0.5-0.5-0.2-0.80.4-0.41.0-0.30.50.50.50.6-0.30.40.4-0.40.30.3
Pavlov. Cond. lever latency1.31.62.6-0.50.70.50.51.40.61.1-1.4-0.1-1.61.41.51.51.5-1.61.61.6-1.61.41.4
Pavlov. Cond. magazine entry latency1.31.75.82.0-2.4-2.0-2.0-1.7-2.4-0.40.62.40.7-0.4-0.1-0.1-0.20.2-0.1-0.10.1-0.2-0.2
Pavlov. Cond. change in total contacts0.20.20.70.4-0.7-0.3-0.3-0.8-0.7-0.10.40.50.6-0.5-0.4-0.4-0.40.4-0.4-0.40.4-0.4-0.4
Pavlov. Cond. index score1.01.32.71.1-1.4-1.1-1.1-1.6-1.4-0.91.11.01.3-1.1-1.0-1.0-1.11.1-1.1-1.11.1-1.0-1.0
Pavlov. Cond. latency score1.72.13.81.3-1.5-1.2-1.2-2.0-1.4-1.21.51.01.7-1.5-1.4-1.4-1.51.5-1.5-1.51.5-1.5-1.5
Pavlov. Cond. lever contacts1.92.33.40.8-0.9-0.8-0.8-1.8-0.8-1.51.70.31.9-1.7-1.7-1.7-1.81.8-1.8-1.81.8-1.7-1.7
Pavlov. Cond. magazine entry number0.50.61.9-1.21.41.11.11.11.40.3-0.5-1.3-0.60.50.30.30.3-0.30.30.3-0.30.40.4
Pavlov. Cond. intertrial magazine entries0.60.81.4-0.10.00.10.10.7-0.00.8-1.00.4-0.91.01.01.01.1-1.21.21.2-1.21.11.1
Pavlov. Cond. lever-magazine prob. diff.1.21.43.01.4-1.6-1.3-1.3-1.7-1.6-0.91.21.31.3-1.1-0.9-0.9-1.01.0-1.0-1.01.0-1.0-1.0
Pavlov. Cond. response bias0.70.92.71.3-1.6-1.3-1.3-1.4-1.6-0.50.61.50.8-0.5-0.4-0.4-0.40.4-0.4-0.40.4-0.4-0.4
Pavlov. Cond. lever latency0.10.20.7-0.60.70.60.60.30.70.00.2-0.80.1-0.2-0.3-0.3-0.40.3-0.2-0.20.2-0.3-0.3
Pavlov. Cond. magazine entry latency0.10.20.60.6-0.7-0.5-0.5-0.4-0.70.10.00.80.10.00.10.10.1-0.30.10.1-0.10.30.3
Pavlov. Cond. change in total contacts0.10.20.60.6-0.6-0.5-0.5-0.1-0.60.0-0.30.8-0.30.30.50.50.4-0.40.20.2-0.20.40.4
Pavlov. Cond. index score0.20.30.90.7-0.7-0.6-0.6-0.2-0.80.1-0.31.0-0.20.30.40.40.5-0.50.30.3-0.30.50.5
Pavlov. Cond. latency score0.20.20.70.7-0.7-0.7-0.7-0.4-0.8-0.1-0.00.90.00.10.20.20.2-0.30.10.1-0.10.30.3
Pavlov. Cond. lever contacts0.30.40.80.5-0.6-0.4-0.40.1-0.70.4-0.60.9-0.50.60.80.80.8-0.70.60.6-0.60.70.7
Pavlov. Cond. magazine entry number0.20.21.0-0.80.90.70.70.61.00.0-0.1-1.0-0.20.0-0.1-0.1-0.10.2-0.0-0.00.0-0.2-0.2
Pavlov. Cond. intertrial magazine entries0.81.01.4-1.00.81.01.01.00.81.0-1.2-0.5-1.11.11.01.01.0-1.01.21.2-1.21.01.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.90.8-0.8-0.7-0.7-0.4-0.9-0.0-0.11.00.00.10.20.20.3-0.30.10.1-0.10.30.3
Pavlov. Cond. response bias0.50.72.31.0-1.1-0.9-0.9-0.3-1.20.3-0.51.5-0.50.70.80.80.8-0.90.70.7-0.70.90.9
Time in closed arm before self-admin1.31.52.6-0.10.40.10.1-0.70.5-1.31.4-1.01.4-1.4-1.6-1.6-1.61.4-1.4-1.41.4-1.6-1.6
Time in closed arm after self-admin0.00.00.10.0-0.1-0.0-0.00.0-0.10.2-0.20.2-0.20.20.20.20.2-0.20.20.2-0.20.20.2
Time in open arm before self-admin0.20.20.80.6-0.7-0.6-0.6-0.3-0.80.1-0.20.9-0.20.30.40.40.4-0.10.10.1-0.10.40.4
Time in open arm after self-admin0.40.41.1-1.01.11.01.00.91.10.5-0.4-1.0-0.50.40.30.30.3-0.30.30.3-0.30.30.3
Bone: periosteal estimation0.20.40.8-0.40.50.30.3-0.30.5-0.60.6-0.80.7-0.6-0.9-0.9-0.70.5-0.5-0.50.5-0.8-0.8
Bone: periosteal perimeter0.50.81.40.6-0.5-0.6-0.6-1.0-0.5-1.01.10.11.1-1.1-1.0-1.0-1.10.9-0.9-0.90.9-1.2-1.2
Bone: post-yield work0.50.61.2-1.10.81.11.10.70.71.0-0.9-0.6-0.70.80.60.60.7-0.70.70.7-0.70.60.6
Progressive ratio test 1 active lever presses0.40.40.7-0.50.30.50.50.70.30.8-0.8-0.1-0.80.70.80.80.7-0.70.70.7-0.70.70.7
Progressive ratio test 1 breakpoint0.40.40.7-0.60.40.60.60.60.30.8-0.8-0.2-0.80.60.70.70.6-0.70.70.7-0.70.70.7
Progressive ratio test 1 inactive lever presses0.00.00.10.2-0.2-0.2-0.2-0.1-0.2-0.00.10.2-0.0-0.20.10.1-0.1-0.10.10.1-0.10.10.1
Progressive ratio test 2 active lever presses0.30.40.8-0.1-0.10.10.10.5-0.20.7-0.70.4-0.80.60.90.90.7-0.70.70.7-0.70.70.7
Progressive ratio test 2 breakpoint0.10.10.20.2-0.3-0.2-0.20.1-0.40.3-0.20.5-0.30.20.50.50.2-0.30.30.3-0.30.30.3
Progressive ratio test 2 inactive lever presses0.10.10.30.2-0.3-0.2-0.2-0.2-0.3-0.40.50.10.3-0.6-0.2-0.2-0.50.5-0.5-0.50.5-0.5-0.5
Incentive Sensitization - Responses0.30.30.7-0.2-0.00.20.20.5-0.10.7-0.60.3-0.70.60.80.80.6-0.60.60.6-0.60.60.6
Incentive Sensitization - Breakpoint0.20.20.5-0.1-0.20.10.10.4-0.20.6-0.50.4-0.60.50.70.70.5-0.50.50.5-0.50.50.5
Sum of active levers in priming session hrs 5-60.00.00.10.1-0.0-0.1-0.1-0.1-0.0-0.20.3-0.10.2-0.3-0.2-0.2-0.30.3-0.3-0.30.3-0.3-0.3
Progressive ratio0.10.10.3-0.50.30.40.40.20.20.5-0.4-0.2-0.20.30.20.20.3-0.20.20.2-0.20.20.2
Food seeking constrained by brief footshock0.60.81.70.9-1.0-0.9-0.9-1.3-1.0-0.81.00.71.0-0.9-0.8-0.8-0.90.7-0.7-0.70.7-0.6-0.6
Seeking ratio, punishment vs. effort0.40.50.90.9-0.7-0.8-0.8-0.9-0.7-0.90.90.50.8-0.9-0.7-0.7-0.90.6-0.6-0.60.6-0.5-0.5
Retroperitoneal fat weight0.20.51.0-1.00.90.90.90.80.80.9-0.8-0.7-0.60.70.40.40.6-0.60.60.6-0.60.40.4
Reaction time number correct2.84.05.6-1.61.31.71.72.01.22.3-2.4-0.6-2.22.22.12.12.1-2.32.22.2-2.22.32.3
Reaction time mean minus median0.20.30.90.6-0.7-0.5-0.5-0.2-0.70.3-0.40.9-0.30.50.50.50.6-0.50.50.5-0.50.50.5
Reaction time mean minus median AUC0.30.30.60.3-0.2-0.3-0.3-0.7-0.2-0.60.6-0.00.8-0.6-0.8-0.8-0.60.7-0.6-0.60.6-0.7-0.7
Reaction time num false alarms1.21.73.1-1.00.71.11.11.40.71.8-1.6-0.2-1.61.41.71.71.4-1.21.31.3-1.31.31.3
Reaction time num false alarms AUC1.72.34.1-1.20.91.31.31.60.82.0-1.9-0.3-1.91.71.91.91.7-1.51.51.5-1.51.51.5
Reaction time trials correct on left2.84.05.6-1.61.31.71.72.01.22.3-2.4-0.6-2.22.22.12.12.1-2.32.22.2-2.22.32.3
Reaction time trials on left2.63.75.2-1.61.31.61.61.91.22.3-2.3-0.6-2.12.22.02.02.0-2.22.12.1-2.12.22.2
Reaction time mean0.00.10.20.10.2-0.0-0.0-0.10.2-0.40.2-0.30.3-0.1-0.4-0.4-0.10.2-0.2-0.20.2-0.2-0.2
Reaction time mean AUC0.10.10.2-0.00.30.00.0-0.10.3-0.40.2-0.40.3-0.1-0.5-0.5-0.20.3-0.3-0.30.3-0.2-0.2
Median of all reaction times0.10.20.6-0.30.60.30.30.10.6-0.40.3-0.80.4-0.3-0.6-0.6-0.40.4-0.5-0.50.5-0.4-0.4
Reaction time omissions0.20.30.80.9-0.5-0.8-0.8-0.6-0.4-0.70.60.40.6-0.4-0.6-0.6-0.30.2-0.1-0.10.1-0.2-0.2
Reaction time false alarm rate0.10.10.2-0.30.20.40.40.40.20.4-0.3-0.2-0.30.20.40.40.20.10.00.0-0.0-0.1-0.1
Reaction time premature initiation rate0.40.51.40.8-0.8-0.8-0.8-0.1-0.90.2-0.41.2-0.50.60.70.70.8-0.70.60.6-0.60.70.7
Reaction time premature initiations1.72.34.00.0-0.2-0.0-0.00.9-0.31.5-1.71.0-1.71.91.81.82.0-2.01.91.9-1.92.02.0
Std. dev. reaction times0.00.10.20.4-0.3-0.3-0.3-0.2-0.30.0-0.20.4-0.00.30.10.10.3-0.20.20.2-0.20.20.2
Reaction time trials completed2.63.75.2-1.61.31.61.61.91.22.3-2.3-0.6-2.12.22.02.02.0-2.22.12.1-2.12.22.2
Reaction time trials AUC3.24.66.5-1.71.31.71.72.11.22.5-2.5-0.5-2.42.42.32.32.3-2.52.42.4-2.42.52.5
Run reversals in cocaine runway, females0.30.30.70.6-0.8-0.8-0.8-0.8-0.8-0.40.40.70.5-0.4-0.4-0.4-0.30.4-0.4-0.40.4-0.3-0.3
Run reversals in cocaine runway, males1.01.02.21.5-1.4-1.5-1.5-1.2-1.4-1.00.91.20.9-0.7-0.6-0.6-0.60.6-0.6-0.60.6-0.6-0.6
Latency to leave start box in cocaine runway2.22.44.61.3-0.9-1.4-1.4-1.3-0.8-2.21.70.41.6-1.6-1.5-1.5-1.61.8-1.8-1.81.8-1.8-1.8
Latency to leave start box in cocaine runway, F3.33.66.30.60.0-0.6-0.6-1.10.2-2.52.1-0.81.9-2.1-2.1-2.1-2.12.5-2.5-2.52.5-2.4-2.4
Latency to leave start box in cocaine runway, M1.11.13.31.0-1.4-1.0-1.0-0.3-1.50.6-0.81.8-0.60.81.01.01.0-1.01.01.0-1.01.01.0
Std. dev. time between licks in bursts0.40.51.01.0-1.0-1.0-1.0-1.0-0.9-0.90.50.90.7-0.4-0.5-0.5-0.50.3-0.3-0.30.3-0.4-0.4
Total sessions with >9 infusions0.10.10.3-0.00.10.00.0-0.20.1-0.40.5-0.20.4-0.5-0.4-0.4-0.50.5-0.5-0.50.5-0.5-0.5
Short access day 1 total inactive lever presses0.10.10.20.3-0.4-0.3-0.3-0.3-0.4-0.20.40.30.2-0.4-0.1-0.1-0.40.2-0.2-0.20.2-0.2-0.2
Short access day 10 total inactive lever presses0.10.10.1-0.20.10.20.20.30.10.4-0.2-0.0-0.30.10.30.30.1-0.30.30.3-0.30.30.3
Short access day 1 total infusions0.90.91.40.8-0.7-0.8-0.8-0.9-0.6-1.11.20.31.0-1.2-0.8-0.8-1.21.1-1.1-1.11.1-1.1-1.1
Short access day 10 total infusions0.20.30.6-0.2-0.10.20.20.4-0.10.7-0.60.3-0.60.50.70.70.5-0.60.60.6-0.60.60.6
Short access total infusions0.00.10.10.0-0.1-0.0-0.0-0.1-0.0-0.20.3-0.00.1-0.3-0.1-0.1-0.30.3-0.3-0.30.3-0.3-0.3
Short access day 1 locomotion0.80.91.51.2-1.2-1.2-1.2-1.1-1.2-1.01.01.00.8-1.0-0.6-0.6-0.90.7-0.7-0.70.7-0.7-0.7
Short access day 10 total locomotion1.01.14.61.7-1.9-1.7-1.7-1.0-2.0-0.10.02.10.10.20.40.40.4-0.30.30.3-0.30.30.3
Short access total locomotion0.40.40.90.9-1.0-0.9-0.9-0.7-1.0-0.50.50.90.4-0.5-0.2-0.2-0.40.4-0.4-0.40.4-0.4-0.4
One hour access (0.3 mA shock)0.10.10.2-0.50.40.50.50.50.40.3-0.3-0.4-0.40.20.30.30.2-0.00.00.0-0.00.00.0
Compulsive drug intake0.50.51.8-0.81.00.80.80.21.1-0.40.4-1.30.4-0.4-0.7-0.7-0.60.6-0.6-0.60.6-0.6-0.6
One hour access (shock baseline)0.50.51.2-0.2-0.10.20.20.6-0.20.9-0.90.5-0.90.91.11.10.9-0.80.80.8-0.80.80.8
Social response proportion1.31.42.61.3-1.1-1.4-1.4-1.5-1.1-1.61.30.81.4-1.1-1.2-1.2-1.10.9-1.0-1.01.0-0.9-0.9
Social responses3.64.710.23.0-3.2-3.1-3.1-2.8-3.2-2.11.92.91.9-1.6-1.2-1.2-1.31.2-1.3-1.31.3-1.2-1.2
Social time0.30.40.9-0.60.70.60.60.30.8-0.50.3-1.00.2-0.5-0.5-0.5-0.50.7-0.8-0.80.8-0.7-0.7
Soleus weight3.710.829.4-5.25.45.35.34.25.42.4-2.2-5.3-2.31.71.21.21.2-1.10.90.9-0.91.11.1
Bone: stiffness0.81.34.4-2.01.92.02.01.12.00.6-0.5-2.1-0.40.3-0.0-0.0-0.1-0.10.10.1-0.10.10.1
Tibialis anterior weight0.41.54.4-2.01.92.12.11.41.91.1-1.0-1.9-0.90.70.50.50.5-0.50.30.3-0.30.40.4
Time to tail flick, vehicle, before self-admin1.31.42.11.1-0.9-1.1-1.1-1.2-0.8-1.41.40.51.3-1.4-1.3-1.3-1.31.1-1.1-1.11.1-1.3-1.3
Time to tail flick, vehicle, after self-admin0.70.81.8-0.2-0.10.20.20.7-0.21.1-1.10.6-1.11.11.41.41.1-0.70.70.7-0.71.11.1
Time to tail flick, test, before self-admin1.21.21.90.8-0.6-0.8-0.8-1.1-0.6-1.31.30.21.2-1.2-1.2-1.2-1.21.4-1.4-1.41.4-1.2-1.2
Time to tail flick, test, after self-admin0.40.40.90.8-0.8-0.8-0.8-0.9-0.7-0.70.60.60.7-0.7-0.6-0.6-0.60.5-0.5-0.50.5-0.6-0.6
Delta time to tail flick, vehicle, before/after SA2.32.33.5-1.30.81.31.31.60.71.9-1.9-0.3-1.91.81.91.91.7-1.41.41.4-1.41.71.7
Delta time to tail flick, test, before/after SA0.60.61.10.0-0.3-0.0-0.00.3-0.40.8-0.80.6-0.70.70.90.90.8-1.11.11.1-1.10.80.8
Tibia length0.20.72.61.3-1.5-1.3-1.3-1.0-1.6-0.20.21.60.3-0.20.10.10.0-0.20.00.0-0.00.10.1
Ambulatory time before self-admin0.20.20.7-0.50.70.50.50.30.7-0.20.2-0.90.2-0.2-0.4-0.4-0.30.1-0.1-0.10.1-0.3-0.3
Ambulatory time after self-admin0.20.30.50.7-0.6-0.7-0.7-0.6-0.6-0.60.60.50.6-0.5-0.5-0.5-0.40.3-0.3-0.30.3-0.4-0.4
Bone: tissue strength0.50.52.2-1.11.31.01.00.61.3-0.10.0-1.50.0-0.1-0.4-0.4-0.30.4-0.4-0.40.4-0.2-0.2
Total heroin consumption0.81.02.51.6-1.6-1.6-1.6-1.2-1.6-0.70.71.50.7-0.6-0.3-0.3-0.40.4-0.4-0.40.4-0.4-0.4
Bone: trabecular number2.03.14.41.6-1.4-1.5-1.5-1.7-1.2-2.02.10.71.9-2.0-1.6-1.6-1.92.0-2.0-2.02.0-1.8-1.8
Bone: trabecular spacing4.86.39.2-1.91.41.81.82.31.23.0-3.0-0.4-2.82.92.72.72.8-3.02.92.9-2.92.82.8
Bone: trabecular thickness6.57.812.21.3-0.5-1.3-1.3-2.1-0.3-3.53.5-0.83.1-3.3-3.3-3.3-3.43.4-3.4-3.43.4-3.3-3.3
Bone: trabecular tissue density1.01.43.0-1.71.61.61.61.21.51.1-1.2-1.4-0.91.10.60.60.8-0.90.90.9-0.91.01.0
Water consumed over 24 hours0.20.20.9-0.70.70.60.60.00.8-0.20.2-1.00.4-0.3-0.7-0.7-0.60.00.10.1-0.1-0.1-0.1
Number of responses in last shaping day0.00.00.10.2-0.3-0.2-0.2-0.0-0.30.00.10.3-0.1-0.20.20.2-0.20.1-0.1-0.10.1-0.1-0.1