Olr35

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr1_163406911_163412515 0.12 0.07 3.7e-10 0.07 0.08 0.08 0.07 5.6e-08 3.6e-09 2.5e-09 1.6e-08
2 Adipose mRNA stability Olr35 0.22 0.1 0.0e+00 0.19 0.22 0.22 0.22 1.7e-20 4.2e-24 1.9e-23 6.8e-24
3 PL alternative TSS XM_063285103.1 0.03 0.03 8.2e-03 0.01 0.01 0.01 0.01 8.6e-03 2.7e-02 2.4e-02 5.7e-02
4 Liver alternative TSS XM_063285069.1 0.27 0.15 0.0e+00 0.11 0.12 0.12 0.12 3.2e-12 5.0e-13 5.3e-13 3.3e-13
5 Liver isoform ratio XM_063285103.1 0.14 0.08 2.3e-09 0.07 0.07 0.06 0.06 1.4e-08 4.5e-08 5.3e-07 1.3e-07
6 Liver alternative TSS XM_063285069.1 0.3 0.13 0.0e+00 0.15 0.16 0.16 0.16 2.8e-16 7.9e-17 2.8e-17 1.1e-17
7 PL gene expression Olr35 0.04 0.03 1.1e-03 0.02 0.01 0.01 0.01 2.2e-03 4.2e-02 2.0e-02 1.4e-02
8 Liver mRNA stability Olr35 0.18 0.09 5.6e-17 0.11 0.11 0.1 0.11 4.2e-12 3.5e-12 9.2e-11 1.4e-12
9 Adipose isoform ratio XM_063285069.1 0.06 0.04 1.2e-06 0.03 0.04 0.03 0.04 7.5e-04 1.6e-05 2.9e-04 5.7e-05
10 Liver intron excision ratio chr1_163450457_163453483 0.06 0.04 1.2e-05 0.03 0.04 0.03 0.03 6.3e-04 7.2e-05 4.1e-04 1.8e-04
11 Adipose isoform ratio XM_063285088.1 0.25 0.12 0.0e+00 0.16 0.17 0.16 0.17 2.3e-17 1.1e-18 7.0e-18 5.0e-18
12 Liver alternative TSS XM_063285103.1 0.2 0.11 4.9e-15 0.1 0.1 0.1 0.1 1.1e-10 3.5e-11 7.9e-11 7.7e-11
13 Liver intron excision ratio chr1_163406911_163409547 0.04 0.03 7.5e-04 0.01 0.02 0.01 0.02 6.9e-03 3.6e-03 8.3e-03 5.4e-03
14 pVTA isoform ratio XM_063285076.1 0.05 0.04 3.9e-03 0.03 0.02 0.02 0.02 2.6e-03 1.3e-02 1.1e-02 8.2e-03
15 IC alternative TSS XM_063285124.1 0.1 0.07 4.8e-03 0.06 0.03 0.04 0.04 1.3e-03 1.6e-02 1.1e-02 5.5e-03
16 Liver isoform ratio XM_063285124.1 0.03 0.02 8.9e-03 0.01 0 0 0 2.5e-02 9.2e-02 2.5e-01 1.1e-01
17 Liver alternative TSS XM_063285124.1 0.47 0.2 1.1e-16 0.06 0.11 0.11 0.11 2.0e-07 2.3e-12 3.6e-12 4.2e-12
18 Liver intron excision ratio chr1_163450457_163451451 0.07 0.06 2.0e-04 0.03 0.02 0.02 0.03 5.4e-04 3.0e-03 3.1e-03 7.5e-04
19 Liver alternative TSS XM_063285103.1 0.38 0.27 5.0e-10 0.04 0.06 0.06 0.06 1.9e-05 9.9e-08 1.5e-07 1.8e-07
20 Adipose isoform ratio XM_063285103.1 0.03 0.03 7.1e-03 0 0.02 0 0.01 7.5e-02 5.7e-03 1.6e-01 2.2e-02
21 Liver intron excision ratio chr1_163409694_163412515 0.05 0.05 1.4e-03 0 0.01 0.01 0.01 9.9e-02 1.3e-02 1.4e-02 3.3e-02
22 Liver gene expression Olr35 0.33 0.12 0.0e+00 0.2 0.2 0.21 0.2 3.1e-21 1.3e-21 1.8e-22 8.2e-22

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.20.41.0-0.00.5-0.2-0.20.4-0.4-0.10.4-0.60.70.7-0.3-0.7-1.01.01.0-0.7-0.40.7-0.6-0.80.5
Area under the delay curve0.10.10.30.0-0.20.30.0-0.20.3-0.1-0.30.4-0.4-0.40.30.40.5-0.5-0.50.50.2-0.50.50.5-0.4
BMI with tail1.13.96.1-1.5-1.21.6-1.61.6-1.5-1.81.41.7-1.8-2.02.22.12.4-2.2-2.32.5-1.7-2.52.42.4-2.2
BMI without tail1.05.38.5-0.9-2.21.3-1.41.4-1.4-1.51.52.6-2.6-2.82.12.82.9-2.8-2.82.5-2.8-2.62.62.7-2.6
Body weight1.77.411.6-1.7-2.11.8-1.91.9-1.8-1.91.72.7-2.8-3.02.83.13.4-3.3-3.33.2-2.8-3.33.23.3-3.1
Weight adjusted by age0.20.71.70.1-1.00.2-0.20.2-0.10.20.11.1-1.1-1.10.61.11.1-1.0-1.30.8-0.9-0.90.91.0-1.0
Bone surface0.30.62.70.9-1.4-0.80.5-0.40.40.7-0.41.2-1.0-1.0-0.30.80.5-0.5-0.4-0.3-1.70.1-0.00.1-0.3
Bone volume0.10.32.00.6-1.0-0.60.2-0.10.10.40.00.8-0.6-0.6-0.20.50.2-0.2-0.2-0.3-1.40.2-0.0-0.0-0.2
Breakpoint value in progressive ratio session0.30.61.7-0.51.30.3-0.30.3-0.2-0.30.1-1.21.21.2-0.2-1.1-1.01.10.9-0.41.20.5-0.5-0.70.6
Number of licking bursts1.03.08.0-2.81.72.6-2.62.6-2.5-2.62.4-1.00.90.62.0-0.20.1-0.10.01.60.1-1.41.30.9-1.0
Context. condit. distance diff. score1.41.74.71.5-1.0-1.92.0-1.92.01.7-2.20.5-0.4-0.2-1.7-0.1-0.30.20.4-1.40.11.3-1.3-1.01.3
Locomotion velocity, session 10.91.02.10.21.0-0.50.5-0.50.40.5-0.2-1.21.21.3-0.9-1.3-1.21.21.2-1.01.51.1-1.1-1.11.2
Locomotion distance, session 10.81.02.01.0-0.2-1.41.4-1.31.31.4-1.3-0.20.20.4-1.4-0.6-0.50.50.5-1.11.11.0-1.1-0.81.2
Locomotion velocity, session 20.10.10.40.6-0.3-0.10.1-0.0-0.0-0.00.20.3-0.4-0.30.00.30.3-0.3-0.40.1-0.0-0.20.20.3-0.4
Locomotion distance, session 20.30.42.01.4-0.5-1.00.9-0.90.80.9-0.60.2-0.2-0.0-0.8-0.1-0.10.20.1-0.70.30.6-0.6-0.30.3
Locomotion velocity, session 31.01.11.91.2-0.0-1.41.4-1.31.31.3-1.4-0.40.40.6-1.4-0.7-0.80.80.8-1.21.01.2-1.2-1.11.1
Locomotion distance, session 31.82.03.31.70.0-1.81.8-1.71.71.8-1.7-0.50.50.8-1.8-1.0-1.01.01.0-1.71.21.6-1.6-1.41.6
Stereotopy head waving bouts, day 30.60.71.2-1.10.01.1-1.01.0-1.0-1.11.10.3-0.3-0.41.10.60.6-0.6-0.71.0-0.5-1.01.00.9-0.9
Stereotopy head waving duration, day 30.10.20.70.9-0.2-0.50.6-0.70.60.5-0.50.1-0.00.0-0.5-0.1-0.20.20.2-0.50.00.4-0.4-0.30.2
Locomotion velocity, session 70.30.30.7-0.10.80.10.0-0.00.10.0-0.2-0.80.80.8-0.3-0.7-0.70.70.7-0.40.80.4-0.5-0.60.5
Locomotion distance, session 70.00.10.2-0.40.30.4-0.30.3-0.3-0.30.1-0.20.20.20.2-0.1-0.10.20.10.20.1-0.10.1-0.0-0.0
Stereotopy head waving bouts, day 71.31.55.52.3-1.0-2.01.7-1.71.71.7-1.60.5-0.4-0.2-1.5-0.1-0.20.20.1-1.20.31.1-1.1-0.70.7
Stereotopy head waving duration, day 71.21.45.92.4-1.5-1.91.7-1.61.61.6-1.51.0-0.9-0.7-1.30.40.3-0.3-0.3-0.9-0.30.8-0.7-0.30.3
Locomotion velocity, session 80.40.51.31.1-0.9-1.01.1-1.01.00.9-1.00.6-0.5-0.4-0.80.20.00.1-0.1-0.7-0.60.6-0.5-0.40.4
Locomotion distance, session 81.11.63.81.9-1.2-1.91.9-1.91.91.7-1.90.7-0.7-0.4-1.60.10.1-0.0-0.0-1.20.21.0-1.0-0.60.9
Degree of sensitization distance2.83.04.5-1.7-0.61.9-1.81.8-1.8-1.91.71.1-1.2-1.42.11.61.6-1.6-1.72.1-1.7-2.12.11.9-2.0
Degree of sensitization stereotypy2.52.810.23.2-1.6-2.72.5-2.42.42.4-2.20.9-0.8-0.4-2.10.10.0-0.0-0.0-1.60.41.4-1.4-0.80.9
Conditioned locomotion0.40.51.10.10.7-0.30.5-0.50.40.6-0.4-0.80.80.8-0.7-0.9-0.80.90.8-0.80.90.8-0.8-0.91.0
Cocaine response after cond. corrected1.21.87.0-2.60.91.9-1.81.8-1.7-1.81.5-0.30.2-0.01.70.30.5-0.6-0.61.60.0-1.51.31.1-0.9
Cocaine response after cond. not corrected0.40.53.2-1.80.61.0-1.01.0-0.9-0.90.7-0.40.30.10.8-0.00.3-0.3-0.20.90.4-0.80.60.5-0.3
Cocaine response before conditioning1.41.74.01.9-0.6-2.01.7-1.61.61.8-1.50.00.10.3-1.8-0.6-0.70.70.8-1.70.51.6-1.5-1.21.3
Saline control response0.60.82.40.9-1.6-0.80.7-0.70.70.7-0.71.4-1.4-1.3-0.21.11.1-1.2-1.10.3-0.8-0.40.30.7-0.6
Bone: connectivity density0.40.61.40.70.2-0.70.5-0.30.30.6-0.3-0.40.60.6-0.8-0.7-1.11.11.1-1.2-0.41.1-1.0-1.10.8
Bone: cortical apparent density0.71.12.7-1.30.91.6-1.61.6-1.6-1.61.6-0.50.50.31.2-0.0-0.00.10.10.9-0.3-0.80.80.5-0.9
Bone: cortical area0.30.51.5-0.3-0.90.1-0.20.3-0.3-0.10.21.0-0.9-1.00.50.90.8-0.8-0.80.6-1.2-0.60.60.6-0.7
Bone: cortical porosity1.21.32.31.00.1-1.31.4-1.51.51.3-1.5-0.40.50.6-1.4-0.8-0.91.00.8-1.21.21.2-1.2-1.11.4
Bone: cortical porosity1.11.22.31.10.1-1.31.4-1.51.51.3-1.4-0.40.40.6-1.4-0.7-0.80.90.8-1.31.21.2-1.2-1.11.4
Bone: cortical thickness0.20.30.8-0.90.80.4-0.50.6-0.6-0.50.5-0.70.70.60.2-0.5-0.50.70.5-0.00.30.1-0.2-0.40.3
Bone: cortical thickness0.10.10.3-0.1-0.1-0.60.4-0.30.30.4-0.4-0.10.10.1-0.4-0.2-0.20.30.1-0.30.40.3-0.4-0.30.5
Bone: cortical tissue density0.60.92.4-1.21.01.5-1.51.5-1.5-1.51.5-0.60.60.41.1-0.2-0.20.20.20.8-0.2-0.70.70.4-0.7
Condit. Reinf. active minus inactive responses0.50.61.4-0.1-0.90.3-0.30.4-0.4-0.30.41.0-1.0-1.00.51.00.9-0.9-1.00.6-1.2-0.70.80.8-0.8
Condit. Reinf. active-inactive response ratio0.91.03.20.0-1.40.1-0.30.4-0.4-0.30.31.4-1.4-1.40.61.41.2-1.1-1.40.7-1.8-0.80.91.0-1.0
Condit. Reinf. active responses0.10.20.30.1-0.40.3-0.20.3-0.3-0.20.40.5-0.5-0.50.40.50.5-0.5-0.50.4-0.5-0.40.50.5-0.6
Condit. Reinf. inactive responses0.10.10.60.30.4-0.00.2-0.30.20.2-0.0-0.50.40.4-0.3-0.4-0.30.30.5-0.30.80.3-0.3-0.30.2
Incentive salience index mean0.40.51.00.3-1.00.1-0.00.1-0.1-0.10.21.0-1.0-0.90.30.90.9-0.8-0.90.5-1.0-0.50.60.7-0.7
Condit. Reinf. lever presses0.10.20.90.9-0.7-0.30.4-0.40.40.4-0.20.6-0.6-0.5-0.20.50.4-0.3-0.5-0.0-0.4-0.00.10.2-0.4
Condit. Reinf. active minus inactive responses2.33.610.12.2-3.2-1.81.8-1.91.91.6-1.92.8-2.8-2.5-0.62.22.1-2.1-2.00.3-1.3-0.60.51.2-0.9
Condit. Reinf. active-inactive response ratio0.40.61.21.0-1.1-0.91.0-1.01.00.8-1.00.9-1.0-0.8-0.40.70.7-0.7-0.70.10.1-0.10.00.4-0.2
Condit. Reinf. active responses4.05.716.72.6-4.1-2.01.9-1.91.91.6-1.83.7-3.6-3.3-0.42.92.8-2.8-2.80.7-2.2-0.90.91.7-1.5
Condit. Reinf. inactive responses2.33.510.21.8-3.2-1.21.0-1.00.90.9-0.72.9-2.9-2.70.02.42.2-2.2-2.30.7-2.3-0.91.01.5-1.5
Condit. Reinf. lever presses6.39.123.84.4-4.9-3.53.6-3.73.73.3-3.74.1-3.9-3.4-1.82.82.6-2.6-2.5-0.5-2.10.1-0.10.8-0.7
Condit. Reinf. lever reinforcers received4.46.218.02.9-4.2-2.22.2-2.22.21.9-2.13.8-3.7-3.4-0.62.92.8-2.8-2.80.5-2.1-0.80.81.6-1.4
Conditioned reinforcement - actives0.31.12.61.4-0.6-1.61.5-1.41.51.5-1.50.2-0.10.1-1.4-0.3-0.30.50.5-1.20.41.1-1.1-0.91.1
Conditioned reinforcement - inactives0.10.20.8-0.30.90.4-0.1-0.00.0-0.40.0-0.80.70.70.1-0.6-0.50.60.40.00.80.1-0.1-0.30.2
Conditioned locomotion2.33.57.02.00.1-2.62.2-2.12.22.2-2.3-0.80.81.1-2.4-1.4-1.31.41.5-2.31.42.2-2.2-2.02.1
Patch foraging indifference point 0 sec1.13.06.92.6-2.6-2.22.3-2.32.42.5-2.42.1-1.9-1.6-1.31.31.0-1.0-1.2-0.8-1.20.5-0.50.0-0.0
Patch foraging indifference point AUC0.51.11.8-0.3-1.00.7-0.60.5-0.5-0.80.51.2-1.2-1.31.01.31.3-1.3-1.31.2-1.4-1.21.21.3-1.3
Delay disc. indifference point, 0s delay0.50.61.40.9-1.2-0.70.7-0.70.70.7-0.71.0-1.1-0.9-0.30.80.9-0.9-0.90.1-0.3-0.20.20.5-0.4
Delay disc. indifference point, 16s delay0.00.00.3-0.10.40.0-0.1-0.00.0-0.1-0.1-0.30.30.30.0-0.3-0.20.30.2-0.00.50.0-0.1-0.10.1
Delay disc. indifference point, 2s delay0.91.01.90.5-1.2-0.00.7-1.11.10.5-1.11.3-1.4-1.30.31.21.4-1.3-1.40.8-0.0-0.90.81.1-0.6
Delay disc. indifference point, 24s delay0.30.51.3-1.10.90.7-1.11.1-1.1-1.11.1-0.70.70.60.6-0.4-0.50.60.50.2-0.1-0.20.2-0.1-0.1
Delay disc. indifference point, 4s delay1.21.33.00.3-1.40.10.1-0.30.3-0.2-0.31.4-1.6-1.50.61.51.7-1.7-1.71.2-0.2-1.21.11.5-1.1
Delay disc. indifference point, 8s delay0.10.10.30.4-0.50.10.3-0.40.40.2-0.40.5-0.5-0.50.10.50.4-0.4-0.40.2-0.3-0.30.30.3-0.3
Indifference point function ln k1.03.05.82.0-0.0-2.22.2-2.22.22.4-2.1-0.60.70.9-2.2-1.2-1.31.41.2-2.11.32.0-2.0-1.81.9
Indifference point function log k1.03.05.82.0-0.0-2.22.2-2.22.22.4-2.1-0.60.70.9-2.2-1.2-1.31.41.2-2.11.32.0-2.0-1.81.9
Patch foraging total patch changes 0 sec0.92.55.82.3-2.4-1.92.1-2.12.22.2-2.22.0-1.9-1.6-1.11.31.0-1.0-1.2-0.5-1.10.3-0.30.2-0.1
Patch foraging total patch changes 12 sec1.41.94.50.3-2.1-0.10.2-0.30.30.2-0.32.1-2.1-2.00.61.91.8-1.8-1.81.0-2.0-1.11.11.3-1.3
Patch foraging total patch changes 18 sec0.81.95.71.2-2.4-0.90.7-0.80.70.6-0.62.2-2.1-2.00.01.81.6-1.6-1.60.4-2.0-0.60.71.0-1.1
Patch foraging total patch changes 24 sec0.31.02.10.1-1.30.10.2-0.30.30.2-0.21.4-1.4-1.40.51.31.4-1.4-1.40.9-0.8-1.00.91.2-0.9
Patch foraging total patch changes 6 sec0.40.71.91.2-1.1-1.01.2-1.11.21.2-1.40.9-0.8-0.7-0.70.50.3-0.3-0.4-0.4-0.60.3-0.3-0.20.2
Patch foraging time to switch 0 sec0.72.56.8-2.12.61.7-1.71.8-1.8-1.81.7-2.22.21.90.7-1.6-1.51.31.50.11.50.1-0.1-0.60.6
Patch foraging water rate 0 sec0.52.04.42.1-2.1-2.02.0-2.02.01.9-1.91.6-1.5-1.3-1.21.00.8-0.7-0.8-0.7-0.80.5-0.5-0.00.1
Patch foraging water rate 12 sec0.51.95.32.3-1.0-1.82.2-2.32.22.2-1.90.5-0.4-0.2-1.6-0.1-0.20.30.3-1.30.21.2-1.2-0.90.8
Patch foraging water rate 18 sec0.20.51.21.0-1.0-0.81.0-1.11.01.0-0.70.8-0.8-0.6-0.50.50.5-0.5-0.4-0.2-0.30.1-0.10.1-0.1
Patch foraging water rate 24 sec1.82.64.81.7-0.1-2.02.1-2.22.12.2-2.0-0.50.50.8-2.0-1.0-1.01.11.2-1.91.11.8-1.8-1.61.7
Patch foraging water rate 6 sec0.71.12.51.5-0.4-1.51.5-1.61.51.5-1.3-0.00.10.2-1.3-0.4-0.60.60.6-1.20.41.1-1.1-0.90.8
Seeking ratio, delayed vs. immediate footshock0.91.32.9-0.71.70.8-1.01.4-1.3-0.61.3-1.71.61.50.0-1.4-1.31.31.4-0.40.90.5-0.5-0.80.6
Distance traveled before self-admin0.10.30.9-0.70.51.0-0.90.9-0.9-0.90.8-0.30.30.20.7-0.1-0.10.20.00.4-0.2-0.40.40.2-0.3
Distance traveled after self-admin1.32.34.5-0.21.9-0.7-0.00.3-0.20.10.2-2.12.12.1-1.0-2.1-2.02.12.1-1.41.81.5-1.5-1.71.5
Extensor digitorum longus weight0.72.84.3-1.1-0.91.7-1.51.4-1.4-1.41.41.4-1.4-1.61.91.71.8-1.7-1.81.9-2.0-2.02.01.9-2.1
Bone: elastic displacement0.91.23.2-0.91.80.7-0.80.8-0.8-0.90.7-1.61.71.50.1-1.3-1.51.51.4-0.30.90.5-0.5-0.90.5
Bone: elastic work1.11.53.8-0.71.90.5-0.80.8-0.8-0.80.7-1.81.91.7-0.1-1.6-1.71.71.7-0.61.00.7-0.7-1.10.7
Bone: endosteal estimation1.33.16.60.7-2.5-0.0-0.00.0-0.1-0.00.22.6-2.6-2.50.92.42.3-2.4-2.31.3-2.5-1.51.61.9-1.8
Bone: endosteal perimeter1.33.17.61.2-2.8-0.30.5-0.50.50.6-0.32.7-2.6-2.50.52.42.2-2.3-2.31.0-2.4-1.21.31.7-1.5
Epididymis fat weight0.21.12.5-1.50.41.5-1.31.2-1.2-1.61.10.0-0.1-0.31.40.50.5-0.4-0.71.4-0.1-1.31.21.0-0.9
Delta time in closed arm before/after self-admin2.82.65.5-1.6-0.12.3-1.91.8-1.8-1.91.80.7-0.7-1.02.11.21.4-1.3-1.22.0-1.4-1.91.91.7-1.8
Delta time in open arm before/after self-admin0.81.02.91.2-1.7-0.91.0-1.11.00.9-0.91.5-1.4-1.3-0.41.11.0-1.0-1.0-0.0-1.1-0.10.20.4-0.4
Diff in mean of infusions in LGA sessions1.52.66.5-2.52.52.2-2.02.0-2.0-2.21.9-2.01.91.71.1-1.3-1.21.31.10.61.3-0.40.3-0.20.3
Delay discount exponential model param0.10.20.30.00.2-0.3-0.00.2-0.20.20.2-0.40.40.4-0.4-0.5-0.50.50.6-0.6-0.20.6-0.5-0.60.4
Extinction: sum of active levers before priming0.10.20.4-0.3-0.30.3-0.20.1-0.1-0.40.30.4-0.4-0.50.50.50.6-0.5-0.60.6-0.2-0.60.60.6-0.6
Active lever presses in extinction session 64.44.48.42.00.4-2.92.4-2.42.42.4-2.6-1.01.11.4-2.6-1.7-1.71.71.6-2.51.92.4-2.5-2.22.3
Bone: final force0.00.00.4-0.70.20.2-0.30.3-0.3-0.20.1-0.10.20.10.2-0.1-0.10.10.10.1-0.3-0.10.0-0.10.1
Bone: final moment0.00.00.2-0.4-0.10.1-0.20.3-0.2-0.10.10.1-0.0-0.10.20.10.00.0-0.00.1-0.5-0.10.1-0.0-0.0
Food consumed during 24 hour testing period1.02.07.22.7-1.5-2.42.1-2.01.92.1-1.50.9-0.8-0.5-1.80.2-0.10.10.1-1.5-0.21.3-1.1-0.60.7
Glucose0.00.00.2-0.40.10.1-0.30.3-0.2-0.40.2-0.00.0-0.00.20.00.00.00.00.2-0.0-0.20.20.1-0.1
Heart weight0.30.41.10.9-0.8-1.01.0-1.01.01.0-1.00.5-0.5-0.4-0.70.20.2-0.2-0.0-0.5-0.30.4-0.4-0.30.4
Delay discount hyperbolic model param0.30.30.70.00.5-0.40.00.2-0.20.20.2-0.60.70.7-0.5-0.7-0.80.80.8-0.80.00.8-0.7-0.80.6
Intermittent access intake day 1-15 change0.21.23.01.7-0.4-1.31.6-1.71.71.6-1.70.10.00.2-1.3-0.4-0.60.70.5-1.20.51.1-1.1-0.90.9
Intermittent access intake escalation0.31.43.41.8-0.5-1.41.7-1.81.81.7-1.80.1-0.00.1-1.4-0.3-0.60.70.4-1.30.41.2-1.1-0.90.9
Intermittent access intake escalation 20.50.82.31.5-0.7-1.11.4-1.51.41.3-1.40.4-0.4-0.2-1.00.0-0.10.10.0-0.80.10.7-0.6-0.50.5
Intermitt. access day 1 inactive lever presses0.10.92.3-1.41.41.5-1.21.1-1.1-1.51.2-1.00.90.71.0-0.5-0.20.20.30.80.8-0.70.60.3-0.3
Intermitt. access day 15 inactive lever presses0.21.02.6-0.51.60.2-0.50.6-0.6-0.60.7-1.61.61.5-0.2-1.4-1.21.21.4-0.41.30.6-0.7-0.90.6
Intermitt. access escalation Index0.00.00.10.1-0.0-0.3-0.10.1-0.1-0.00.1-0.00.10.1-0.1-0.10.1-0.00.2-0.1-0.20.1-0.1-0.10.0
Intermittent access day 1 total infusions0.10.31.21.0-0.6-1.10.7-0.50.50.8-0.60.4-0.3-0.2-0.80.00.00.00.1-0.6-0.30.6-0.6-0.40.3
Intermittent access day 15 total infusions0.51.33.41.8-0.6-1.71.6-1.61.61.6-1.60.2-0.10.1-1.5-0.3-0.40.60.6-1.30.21.2-1.2-1.00.9
Intermittent access terminal intake (last 3 days)0.71.23.51.9-1.0-1.81.6-1.51.51.6-1.50.6-0.5-0.3-1.40.0-0.00.20.2-1.1-0.11.0-1.0-0.70.7
Intermittent access total infusions0.40.51.61.3-1.0-1.10.9-0.80.90.9-0.90.7-0.6-0.5-0.80.30.3-0.2-0.1-0.6-0.50.5-0.4-0.30.2
Intermittent access day 1 locomotion0.20.40.80.80.1-0.70.6-0.50.50.7-0.6-0.40.50.5-0.8-0.6-0.60.60.7-0.90.20.9-0.9-0.90.7
Intermittent access day 15 total locomotion0.52.03.61.9-0.1-1.81.8-1.81.81.8-1.8-0.30.40.6-1.8-0.8-1.01.01.0-1.70.71.7-1.6-1.51.4
Intermittent access total locomotion0.40.51.61.2-0.3-1.11.0-0.90.91.0-1.00.10.00.1-1.0-0.3-0.30.30.4-0.9-0.00.9-0.8-0.70.6
Intermittent access standard deviation0.10.61.30.1-1.00.1-0.20.2-0.3-0.30.31.0-1.0-1.00.51.00.9-0.9-1.00.7-1.1-0.70.80.9-1.0
Left kidney weight0.43.45.7-0.4-1.90.9-0.90.8-0.8-1.01.12.1-2.2-2.31.62.32.4-2.4-2.42.0-2.0-2.12.12.3-2.2
Right kidney weight0.74.67.8-0.5-2.21.0-1.01.0-1.0-1.01.22.5-2.6-2.71.92.72.7-2.7-2.82.3-2.5-2.42.42.6-2.5
Cocaine induced anxiety0.20.61.4-1.01.11.0-1.11.2-1.2-1.01.2-0.90.90.70.6-0.6-0.50.50.70.1-0.1-0.10.1-0.2-0.1
Post-drug Anxiety0.70.81.9-1.41.11.3-1.31.2-1.2-1.21.3-0.80.80.60.9-0.4-0.50.40.50.5-0.1-0.40.40.1-0.3
Baseline Anxiety0.10.10.30.0-0.5-0.00.1-0.20.20.1-0.10.6-0.6-0.50.20.50.3-0.4-0.50.3-0.3-0.30.40.4-0.4
Tail length1.47.312.4-0.8-2.81.3-1.51.5-1.5-1.51.83.2-3.2-3.32.43.43.4-3.3-3.32.8-3.5-2.93.03.2-3.2
Length with tail1.14.98.0-0.8-2.21.1-1.21.2-1.2-1.01.32.5-2.6-2.72.02.72.8-2.8-2.82.4-2.6-2.52.52.7-2.6
Length without tail0.00.20.7-0.80.40.6-0.60.6-0.6-0.50.6-0.20.1-0.00.60.10.3-0.3-0.30.70.3-0.60.50.5-0.5
Times rat made contact with spout1.01.12.0-0.7-0.41.2-1.21.2-1.3-1.21.40.6-0.7-0.81.20.90.9-0.9-0.81.1-1.2-1.11.21.1-1.3
Lifetime Intake0.50.61.91.4-1.0-1.21.1-1.11.11.1-1.20.7-0.6-0.5-0.90.30.3-0.2-0.1-0.7-0.30.6-0.5-0.30.3
Liver weight, left1.11.93.1-1.1-0.71.3-1.31.2-1.3-1.31.31.0-1.1-1.31.61.41.5-1.5-1.41.7-1.3-1.71.71.7-1.7
Liver weight, right2.64.67.7-2.3-0.32.3-2.62.7-2.7-2.52.80.9-1.1-1.32.61.61.7-1.8-1.72.6-1.6-2.52.52.3-2.4
Locomotor activity0.40.72.81.7-1.1-1.21.2-1.21.11.4-0.80.7-0.6-0.4-0.90.20.1-0.1-0.1-0.8-0.40.7-0.6-0.30.3
Locomotor testing distance0.61.44.31.9-2.1-1.01.1-1.01.01.2-0.71.7-1.7-1.5-0.41.31.2-1.2-1.1-0.0-1.1-0.10.20.6-0.6
Locomotor testing rearing0.41.53.10.7-1.70.10.0-0.0-0.00.20.21.7-1.8-1.70.61.71.7-1.7-1.61.0-1.4-1.11.11.4-1.3
Locomotion in novel chamber1.41.83.31.7-0.0-1.81.7-1.61.61.4-1.6-0.50.50.8-1.8-1.0-1.01.01.1-1.70.91.7-1.6-1.51.4
Locomotion in novel chamber post-restriction0.92.88.92.3-0.7-1.92.7-3.03.02.6-2.80.3-0.20.1-1.8-0.3-0.20.30.4-1.41.11.3-1.3-1.11.3
Fecal boli incidents, locomotor time 10.41.22.41.1-0.1-1.51.3-1.11.11.2-1.0-0.40.40.6-1.5-0.8-0.80.90.9-1.40.71.4-1.4-1.21.3
Change in fecal boli incidents, locomotor task0.30.31.2-1.10.81.0-0.80.6-0.6-0.90.5-0.60.50.40.7-0.3-0.20.20.30.50.2-0.40.30.1-0.2
Time >=10cm from walls, locomotor time 11.21.64.11.6-0.6-1.81.9-1.92.02.0-2.00.2-0.10.1-1.5-0.3-0.20.20.3-1.20.71.1-1.1-0.91.1
Bouts of movement, locomotor time 10.00.00.40.2-0.2-0.60.3-0.30.30.1-0.30.1-0.1-0.0-0.3-0.0-0.00.0-0.0-0.10.20.1-0.2-0.1-0.0
Total resting periods, locomotor time 10.30.40.70.20.4-0.90.5-0.40.40.3-0.4-0.60.60.6-0.7-0.7-0.70.80.7-0.70.50.7-0.8-0.70.5
Rest time, locomotor task time 10.40.71.5-0.40.9-0.60.10.1-0.1-0.20.1-1.11.01.1-0.6-1.1-1.21.21.1-0.70.80.8-0.9-0.90.9
Distance moved, locomotor task time 10.41.22.3-0.1-1.20.7-0.50.4-0.4-0.40.41.4-1.3-1.40.91.41.4-1.5-1.31.0-1.5-1.11.21.2-1.3
Vertical activity count, locomotor time 10.10.92.00.4-1.30.40.1-0.30.3-0.0-0.41.4-1.3-1.40.61.31.4-1.4-1.10.7-1.3-0.80.90.9-1.0
Time >=10cm from walls, locomotor time 20.10.41.30.4-1.1-0.80.7-0.50.60.8-0.70.9-1.0-0.8-0.30.70.8-0.8-0.70.1-0.3-0.10.10.40.0
Bouts of movement, locomotor time 20.20.71.60.4-1.00.30.3-0.50.50.2-0.51.1-1.2-1.10.51.11.3-1.2-1.10.8-0.5-0.90.81.0-0.8
Total resting periods, locomotor time 20.10.51.10.2-0.70.50.2-0.40.40.0-0.40.9-0.9-0.90.50.91.1-1.0-1.00.8-0.2-0.90.80.9-0.7
Rest time, locomotor task time 20.71.32.9-1.71.71.5-1.51.5-1.5-1.51.4-1.31.31.10.8-0.8-1.01.00.90.30.4-0.20.2-0.20.1
Distance moved, locomotor task time 21.11.44.01.1-2.0-1.21.1-1.11.11.0-1.11.7-1.7-1.6-0.41.31.5-1.5-1.30.2-0.9-0.30.30.7-0.6
Vertical activity count, locomotor time 20.51.12.90.6-1.7-0.30.5-0.60.60.2-0.61.7-1.6-1.60.21.41.5-1.5-1.20.5-1.3-0.60.70.9-0.9
Light reinforcement 10.31.34.0-1.71.22.0-1.71.8-1.8-1.51.8-0.80.70.51.3-0.20.0-0.00.11.00.1-0.90.80.5-0.6
Light reinforcement 20.10.20.50.10.60.10.00.1-0.10.10.1-0.70.70.7-0.4-0.7-0.50.50.7-0.50.50.5-0.5-0.60.4
Bone: marrow area1.23.06.10.5-2.40.1-0.20.2-0.2-0.10.32.5-2.5-2.41.02.42.3-2.3-2.31.4-2.5-1.51.61.9-1.8
Bone: maximum diameter1.02.05.50.8-2.3-0.50.5-0.50.50.6-0.62.2-2.2-2.10.31.91.8-1.8-1.80.7-2.0-0.90.91.2-1.0
Bone: maximum force0.00.00.2-0.3-0.10.1-0.10.2-0.1-0.0-0.00.1-0.0-0.10.10.10.00.0-0.0-0.0-0.5-0.00.0-0.10.1
Bone: maximum moment0.00.00.5-0.1-0.3-0.0-0.10.1-0.10.0-0.00.3-0.2-0.30.10.30.1-0.1-0.10.0-0.7-0.00.1-0.0-0.1
Mean time between licks in bursts0.85.010.90.9-3.3-0.10.4-0.50.40.5-0.23.3-3.3-3.20.93.03.1-3.1-3.11.7-2.5-1.91.92.4-2.1
Mean num. licks in bursts0.82.27.32.7-1.8-2.32.2-2.12.12.2-1.91.2-1.1-0.8-1.70.40.1-0.1-0.2-1.3-0.51.1-1.0-0.60.5
Cd content in liver0.70.81.3-0.9-0.11.1-1.01.0-1.0-1.10.90.4-0.5-0.61.10.70.8-0.8-0.81.1-0.7-1.11.11.0-1.1
Co content in liver1.01.12.70.9-1.6-0.20.2-0.20.20.2-0.01.6-1.6-1.50.31.41.4-1.4-1.40.6-1.2-0.70.81.1-1.1
Cu content in liver1.82.14.1-0.1-1.40.8-0.60.6-0.7-0.61.01.6-1.8-1.71.21.82.0-2.0-1.91.6-1.2-1.71.72.0-1.7
Fe content in liver0.00.00.2-0.50.20.2-0.20.1-0.1-0.20.1-0.20.10.10.2-0.10.0-0.00.00.20.3-0.20.10.1-0.0
K content in liver0.30.30.6-0.0-0.20.7-0.30.2-0.3-0.40.60.4-0.5-0.50.60.60.6-0.6-0.60.6-0.3-0.70.70.8-0.6
Mg content in liver0.10.10.30.4-0.3-0.10.5-0.50.50.4-0.40.2-0.3-0.2-0.20.10.3-0.3-0.2-0.00.40.0-0.00.10.2
Mn content in liver1.41.63.2-0.31.7-0.00.2-0.10.10.2-0.1-1.81.81.8-0.7-1.7-1.61.61.7-1.01.81.1-1.2-1.31.4
Na content in liver0.30.31.20.7-0.5-0.61.0-1.11.10.9-1.00.3-0.4-0.2-0.60.10.2-0.2-0.2-0.40.50.3-0.3-0.10.5
Rb content in liver0.20.21.11.0-0.8-0.40.5-0.50.40.6-0.20.6-0.6-0.5-0.30.40.3-0.3-0.2-0.3-0.80.2-0.10.0-0.2
Se content in liver2.42.88.0-2.32.81.4-1.51.6-1.6-1.61.6-2.52.42.20.5-1.9-1.71.71.60.02.00.2-0.3-0.70.8
Sr content in liver0.40.40.50.50.2-0.60.6-0.60.60.6-0.7-0.30.40.4-0.7-0.5-0.60.60.6-0.70.50.7-0.7-0.70.7
Zn content in liver1.41.64.61.4-2.1-0.80.9-0.90.80.8-0.61.9-1.9-1.8-0.11.61.6-1.6-1.60.4-1.1-0.60.61.0-0.8
Bone: minimum diameter2.03.86.8-0.5-1.91.0-1.21.2-1.2-1.11.22.2-2.2-2.31.82.42.3-2.4-2.32.0-2.6-2.12.22.3-2.3
Time in familiar zone, hab. session 10.30.30.5-0.4-0.20.5-0.60.5-0.5-0.60.70.4-0.4-0.40.60.50.6-0.6-0.50.6-0.6-0.60.60.6-0.6
Time in novel zone, hab. session 10.10.10.2-0.40.30.4-0.40.5-0.4-0.40.2-0.20.20.10.3-0.0-0.20.10.00.3-0.1-0.20.20.1-0.3
Total zone transitions, hab. session 10.60.81.40.90.5-0.70.8-0.70.70.8-0.9-0.70.80.8-1.1-0.9-1.01.01.0-1.20.71.2-1.1-1.21.1
Total locomotion distance, hab. session 11.62.33.7-1.6-0.21.8-1.81.9-1.9-1.81.70.7-0.8-1.01.81.21.4-1.4-1.31.9-1.1-1.81.81.7-1.6
Locomotion velocity, hab. session 10.91.32.1-1.2-0.21.3-1.31.5-1.4-1.31.20.6-0.6-0.81.40.91.1-1.1-1.01.4-0.9-1.41.31.3-1.2
Time in familiar zone, hab. session 20.70.82.51.1-1.6-0.70.5-0.50.50.6-0.31.4-1.3-1.2-0.11.11.0-0.8-0.9-0.0-1.6-0.10.30.5-0.6
Time in novel zone, hab. session 20.40.52.2-0.41.10.1-0.00.1-0.0-0.0-0.1-1.11.01.0-0.2-0.9-0.80.70.8-0.21.50.3-0.5-0.50.6
Total zone transitions, hab. session 21.21.53.31.6-0.4-1.71.8-1.71.71.7-1.8-0.00.10.3-1.6-0.5-0.60.60.5-1.30.91.3-1.3-1.11.2
Total locomotion distance, hab. session 21.41.92.9-1.0-0.91.0-1.01.1-1.1-1.01.11.2-1.3-1.41.41.51.6-1.6-1.61.7-1.2-1.71.61.7-1.6
Locomotion velocity, hab. session 21.72.33.8-1.2-0.91.3-1.21.3-1.3-1.21.21.3-1.4-1.51.71.61.8-1.8-1.81.9-1.2-1.91.81.9-1.8
Novel to familiar place preference ratio0.00.00.2-0.10.1-0.20.1-0.00.10.1-0.4-0.10.10.1-0.2-0.1-0.1-0.10.1-0.00.50.1-0.1-0.10.2
Novelty place preference0.00.00.3-0.10.1-0.20.10.00.00.1-0.3-0.10.10.1-0.2-0.2-0.1-0.10.1-0.00.50.0-0.1-0.10.2
Time in novel zone, NPP test0.00.10.20.2-0.1-0.50.3-0.20.20.3-0.4-0.0-0.00.1-0.3-0.1-0.0-0.10.1-0.20.50.2-0.2-0.10.2
Total zone transitions, NPP test0.40.60.90.60.2-0.90.9-0.90.80.9-0.7-0.50.50.6-1.0-0.7-0.60.60.7-0.90.90.9-0.9-0.80.9
Total locomotion distance, NPP test1.21.73.2-1.8-0.01.4-1.51.5-1.5-1.41.50.4-0.6-0.71.60.91.2-1.3-1.11.8-0.2-1.71.51.6-1.3
Locomotion velocity, NPP test1.31.94.6-2.10.31.6-1.71.7-1.7-1.71.70.1-0.4-0.51.70.71.1-1.1-1.01.9-0.1-1.71.61.5-1.2
Intraocular pressure0.81.42.71.50.3-1.11.5-1.61.61.4-1.6-0.60.60.8-1.3-0.9-0.90.80.9-1.31.21.3-1.3-1.21.2
Delta distance traveled before/after self-admin1.82.03.91.30.3-2.01.5-1.41.41.7-1.3-0.80.81.1-1.8-1.2-1.11.21.3-1.71.31.7-1.7-1.51.6
Delta ambulatory time before/after self-admin1.32.24.01.30.4-2.01.6-1.51.51.7-1.4-0.90.91.1-1.8-1.3-1.21.21.4-1.81.51.8-1.8-1.61.6
Parametrial fat weight0.41.02.6-1.60.51.6-1.41.3-1.3-1.41.1-0.10.0-0.21.40.40.3-0.4-0.61.2-0.4-1.21.10.8-0.9
Pavlov. Cond. lever latency0.70.92.7-1.71.61.0-0.90.9-0.8-0.90.5-1.31.31.10.5-1.0-0.80.70.80.21.1-0.1-0.1-0.40.5
Pavlov. Cond. magazine entry latency1.41.75.41.7-2.3-1.41.3-1.21.21.3-1.22.0-1.9-1.7-0.61.41.2-1.2-1.4-0.1-1.4-0.10.10.6-0.5
Pavlov. Cond. change in total contacts0.50.51.60.8-1.2-0.80.7-0.60.60.7-0.61.0-1.1-0.9-0.40.80.8-0.7-0.8-0.0-0.5-0.10.10.4-0.2
Pavlov. Cond. index score1.31.65.21.8-2.3-1.31.1-1.01.01.2-0.82.0-1.9-1.7-0.51.51.2-1.1-1.4-0.1-1.6-0.10.20.6-0.7
Pavlov. Cond. latency score1.21.54.81.8-2.2-1.31.2-1.11.11.2-0.91.9-1.8-1.6-0.51.41.1-1.0-1.3-0.2-1.5-0.00.20.5-0.6
Pavlov. Cond. lever contacts0.70.82.61.4-1.6-0.80.7-0.70.60.7-0.31.4-1.3-1.2-0.21.10.9-0.8-1.0-0.0-1.2-0.10.20.5-0.6
Pavlov. Cond. magazine entry number1.41.85.3-1.92.31.5-1.41.3-1.3-1.31.2-2.01.91.70.6-1.4-1.21.11.40.21.30.0-0.1-0.50.5
Pavlov. Cond. intertrial magazine entries0.70.82.1-1.21.40.7-0.90.9-0.9-0.71.0-1.31.21.10.3-1.0-0.80.80.90.11.10.1-0.1-0.30.5
Pavlov. Cond. lever-magazine prob. diff.1.01.34.21.6-2.0-1.10.9-0.90.81.0-0.61.8-1.7-1.5-0.41.31.0-0.9-1.2-0.1-1.5-0.10.20.6-0.6
Pavlov. Cond. response bias0.70.92.81.4-1.7-0.90.8-0.70.70.8-0.41.4-1.4-1.2-0.31.10.9-0.8-1.0-0.1-1.2-0.10.20.5-0.5
Pavlov. Cond. lever latency7.09.824.5-5.04.84.0-4.24.2-4.2-4.04.2-3.83.63.12.4-2.4-2.22.12.11.11.5-0.70.7-0.30.2
Pavlov. Cond. magazine entry latency1.82.66.92.5-1.8-2.32.4-2.42.52.3-2.61.3-1.1-0.8-1.80.50.3-0.3-0.2-1.3-0.31.1-1.1-0.70.7
Pavlov. Cond. change in total contacts2.97.116.44.1-3.9-3.53.7-3.73.83.6-3.83.0-2.9-2.4-2.21.81.7-1.6-1.7-1.0-0.80.7-0.80.10.1
Pavlov. Cond. index score4.77.418.04.2-4.0-3.43.7-3.83.83.6-3.93.2-3.0-2.5-2.21.91.7-1.7-1.6-1.1-1.10.8-0.80.10.1
Pavlov. Cond. latency score4.16.616.74.1-3.6-3.33.6-3.73.73.5-3.82.8-2.7-2.2-2.21.61.4-1.4-1.4-1.2-0.90.9-0.9-0.10.2
Pavlov. Cond. lever contacts6.49.422.94.8-4.7-3.84.0-4.14.13.8-4.13.8-3.6-3.1-2.22.42.2-2.2-2.2-1.0-1.60.6-0.60.4-0.3
Pavlov. Cond. magazine entry number3.24.210.6-3.22.33.0-3.13.1-3.1-2.93.2-1.61.51.12.2-0.6-0.50.50.51.50.1-1.31.30.7-0.8
Pavlov. Cond. intertrial magazine entries1.02.23.2-1.0-1.11.1-1.21.2-1.2-1.11.41.3-1.4-1.51.51.61.7-1.7-1.71.7-1.7-1.71.71.8-1.7
Pavlov. Cond. lever-magazine prob. diff.4.46.815.74.0-3.9-3.23.5-3.53.63.4-3.73.1-3.0-2.5-2.02.01.8-1.8-1.7-0.9-1.20.6-0.60.2-0.1
Pavlov. Cond. response bias7.09.724.95.0-4.7-4.04.2-4.24.34.0-4.33.7-3.5-3.0-2.52.32.0-2.0-1.9-1.3-1.50.9-0.80.1-0.1
Time in closed arm before self-admin1.42.56.11.7-0.1-2.51.8-1.51.51.8-1.6-0.60.70.9-2.1-1.2-1.31.31.3-2.11.02.0-2.0-1.81.7
Time in closed arm after self-admin0.91.02.3-0.21.4-0.0-0.20.3-0.3-0.20.4-1.51.51.4-0.5-1.4-1.41.41.5-0.81.00.9-0.9-1.10.9
Time in open arm before self-admin1.01.24.2-1.61.22.0-1.61.4-1.4-1.51.3-0.70.60.41.3-0.10.1-0.1-0.11.10.4-1.00.90.7-0.5
Time in open arm after self-admin1.21.32.50.1-1.20.7-0.30.1-0.1-0.30.11.5-1.5-1.50.91.51.4-1.5-1.61.1-1.4-1.21.31.3-1.3
Bone: periosteal estimation1.02.35.00.3-2.2-0.0-0.10.2-0.2-0.00.12.2-2.2-2.20.82.12.0-2.0-2.01.2-2.2-1.31.41.6-1.5
Bone: periosteal perimeter1.12.15.20.8-2.2-0.10.2-0.10.10.30.02.2-2.1-2.10.62.01.8-1.9-1.80.9-2.3-1.01.11.4-1.4
Bone: post-yield work0.10.21.20.0-0.60.0-0.10.1-0.10.0-0.00.6-0.5-0.60.20.50.4-0.3-0.40.1-1.1-0.20.20.2-0.3
Progressive ratio test 1 active lever presses0.30.50.90.00.8-0.20.2-0.30.30.2-0.3-0.90.90.9-0.5-0.9-0.70.80.9-0.70.90.7-0.7-0.80.9
Progressive ratio test 1 breakpoint0.30.40.80.10.8-0.20.2-0.20.30.2-0.3-0.90.90.9-0.5-0.9-0.70.70.9-0.60.90.7-0.7-0.80.9
Progressive ratio test 1 inactive lever presses0.10.20.70.00.80.3-0.0-0.10.0-0.2-0.0-0.80.80.7-0.1-0.7-0.50.50.7-0.30.70.3-0.4-0.50.4
Progressive ratio test 2 active lever presses0.10.20.40.6-0.6-0.40.5-0.50.50.4-0.60.5-0.5-0.4-0.20.40.6-0.4-0.2-0.1-0.30.0-0.00.10.1
Progressive ratio test 2 breakpoint0.10.20.40.7-0.6-0.40.5-0.60.60.5-0.60.5-0.5-0.4-0.30.30.5-0.3-0.2-0.2-0.20.1-0.10.00.1
Progressive ratio test 2 inactive lever presses0.10.20.60.7-0.1-0.60.5-0.50.50.4-0.5-0.00.10.2-0.5-0.2-0.30.40.4-0.50.10.5-0.5-0.50.3
Incentive Sensitization - Responses0.20.61.71.0-1.3-0.60.7-0.70.80.6-0.81.2-1.1-1.0-0.20.91.0-0.8-0.70.0-0.8-0.20.20.4-0.3
Incentive Sensitization - Breakpoint0.20.51.41.1-1.2-0.70.7-0.80.80.7-0.81.1-1.0-0.9-0.30.80.8-0.6-0.6-0.1-0.7-0.00.10.3-0.2
Sum of active levers in priming session hrs 5-60.10.10.20.20.0-0.20.3-0.30.30.5-0.2-0.10.10.2-0.3-0.2-0.20.30.0-0.20.30.2-0.3-0.20.1
Progressive ratio0.20.51.11.0-0.1-0.91.0-0.91.01.1-1.0-0.10.10.3-1.0-0.4-0.30.40.4-0.80.50.8-0.8-0.70.8
Food seeking constrained by brief footshock1.01.33.30.5-1.8-0.30.5-0.50.60.3-0.61.8-1.8-1.70.21.51.5-1.6-1.60.7-1.2-0.80.81.1-0.8
Seeking ratio, punishment vs. effort0.92.03.4-0.6-1.50.7-0.70.5-0.5-0.80.61.7-1.7-1.81.31.81.8-1.8-1.91.5-1.6-1.61.61.7-1.5
Retroperitoneal fat weight3.113.823.0-4.5-0.14.6-4.64.5-4.4-4.74.31.4-1.5-2.14.82.72.7-2.7-2.94.6-2.8-4.44.33.9-4.1
Reaction time number correct0.51.92.91.10.6-1.41.4-1.41.31.3-1.0-1.11.11.3-1.6-1.4-1.51.51.4-1.71.31.7-1.7-1.61.5
Reaction time mean minus median0.10.71.90.5-1.4-0.40.2-0.20.20.2-0.41.3-1.3-1.20.21.11.1-1.2-1.10.4-1.1-0.50.50.7-0.8
Reaction time mean minus median AUC0.10.51.30.9-1.1-1.10.8-0.70.70.8-0.80.9-0.8-0.7-0.50.50.5-0.5-0.4-0.3-0.60.2-0.2-0.0-0.0
Reaction time num false alarms0.91.53.5-1.80.81.9-1.81.8-1.8-1.71.8-0.30.20.01.60.20.4-0.4-0.51.3-0.4-1.21.20.9-0.9
Reaction time num false alarms AUC0.30.71.8-1.40.71.3-1.31.2-1.3-1.21.3-0.30.30.11.00.10.2-0.2-0.30.9-0.1-0.80.80.6-0.5
Reaction time trials correct on left0.51.92.91.10.6-1.41.4-1.41.31.3-1.0-1.11.11.3-1.6-1.4-1.51.51.4-1.71.31.7-1.7-1.61.5
Reaction time trials on left0.61.92.91.10.7-1.41.4-1.41.41.3-1.1-1.11.11.3-1.6-1.4-1.51.51.4-1.71.41.7-1.7-1.61.5
Reaction time mean0.61.32.9-1.70.31.5-1.61.7-1.6-1.71.30.1-0.1-0.31.50.50.6-0.7-0.51.3-0.7-1.21.20.9-1.1
Reaction time mean AUC0.51.23.3-1.80.81.5-1.71.8-1.7-1.71.4-0.40.40.11.30.10.2-0.3-0.11.1-0.3-1.00.90.6-0.8
Median of all reaction times1.01.54.2-2.10.91.7-1.92.0-1.9-1.91.5-0.40.40.11.50.10.2-0.3-0.21.2-0.3-1.11.00.7-0.9
Reaction time omissions0.40.61.1-0.7-0.30.8-0.50.4-0.4-0.70.30.6-0.6-0.70.90.81.0-1.0-0.91.1-0.5-1.01.00.9-0.9
Reaction time false alarm rate1.31.83.8-1.90.51.9-1.91.9-1.9-1.81.70.0-0.1-0.31.70.60.8-0.8-0.81.6-0.6-1.51.51.2-1.1
Reaction time premature initiation rate2.53.87.1-0.3-2.40.6-0.50.4-0.4-0.70.32.7-2.6-2.71.42.62.6-2.6-2.51.8-2.7-1.92.02.1-2.1
Reaction time premature initiations0.41.33.50.5-1.9-0.40.5-0.50.50.2-0.51.8-1.7-1.70.21.51.5-1.4-1.40.6-1.6-0.70.70.9-1.0
Std. dev. reaction times0.51.62.8-0.5-1.20.7-0.80.8-0.7-0.90.51.5-1.4-1.51.21.61.7-1.7-1.51.4-1.5-1.41.41.4-1.5
Reaction time trials completed0.61.92.91.10.7-1.41.4-1.41.41.3-1.1-1.11.11.3-1.6-1.4-1.51.51.4-1.71.41.7-1.7-1.61.5
Reaction time trials AUC0.41.42.01.00.5-1.21.3-1.31.21.2-0.9-0.80.91.0-1.4-1.1-1.21.21.1-1.41.21.4-1.4-1.31.3
Run reversals in cocaine runway, females4.55.07.3-1.7-1.12.3-2.22.1-2.1-2.42.01.8-1.8-2.12.62.32.2-2.2-2.32.6-2.4-2.72.72.6-2.6
Run reversals in cocaine runway, males0.10.10.3-0.30.30.2-0.20.2-0.2-0.60.2-0.30.30.30.1-0.2-0.40.30.3-0.1-0.00.1-0.1-0.20.1
Latency to leave start box in cocaine runway1.62.27.2-2.41.22.7-1.91.6-1.6-1.91.6-0.40.3-0.02.10.40.6-0.7-0.71.90.4-1.81.71.3-1.1
Latency to leave start box in cocaine runway, F2.93.69.3-2.80.63.0-2.32.0-2.0-2.12.00.2-0.4-0.72.61.11.4-1.4-1.42.5-0.3-2.42.32.1-1.7
Latency to leave start box in cocaine runway, M0.30.30.8-0.20.90.2-0.0-0.10.1-0.2-0.1-0.80.80.8-0.1-0.7-0.70.70.7-0.30.90.4-0.4-0.50.5
Std. dev. time between licks in bursts1.83.46.50.1-2.20.7-0.20.0-0.1-0.10.42.4-2.5-2.41.32.42.6-2.6-2.51.8-2.0-1.92.02.3-2.0
Total sessions with >9 infusions0.70.82.01.4-1.3-1.01.3-1.31.31.2-1.41.0-1.0-0.8-0.80.60.5-0.5-0.5-0.5-0.40.3-0.3-0.00.2
Short access day 1 total inactive lever presses0.00.00.10.00.20.4-0.10.0-0.1-0.20.1-0.10.10.10.1-0.1-0.20.10.10.10.2-0.10.10.0-0.1
Short access day 10 total inactive lever presses0.10.51.4-0.61.20.4-0.60.6-0.6-0.60.7-1.11.11.00.1-0.9-0.90.90.9-0.10.80.2-0.3-0.40.2
Short access day 1 total infusions0.71.44.01.3-2.0-1.01.1-1.11.11.1-1.21.8-1.8-1.6-0.41.41.4-1.3-1.30.1-1.0-0.30.30.7-0.4
Short access day 10 total infusions0.30.51.31.0-1.1-0.90.8-0.70.70.7-0.80.9-0.9-0.8-0.50.60.6-0.5-0.5-0.2-0.40.1-0.10.2-0.0
Short access total infusions0.50.71.61.3-1.2-1.11.2-1.21.21.1-1.21.0-0.9-0.8-0.70.60.7-0.6-0.5-0.4-0.30.3-0.3-0.00.2
Short access day 1 locomotion1.01.64.72.1-0.9-1.71.9-1.92.01.8-2.20.5-0.4-0.2-1.5-0.1-0.00.20.1-1.30.21.1-1.1-0.81.0
Short access day 10 total locomotion0.20.92.91.7-1.2-1.31.4-1.31.31.4-1.30.8-0.8-0.6-1.00.40.4-0.4-0.2-0.7-0.40.5-0.5-0.20.2
Short access total locomotion0.50.71.91.2-0.4-1.01.3-1.21.31.2-1.40.1-0.00.1-1.0-0.3-0.20.20.3-0.90.20.9-0.8-0.70.8
One hour access (0.3 mA shock)0.60.71.91.4-0.8-1.21.3-1.31.31.1-1.30.4-0.3-0.2-1.1-0.0-0.00.20.2-0.9-0.10.8-0.8-0.60.6
Compulsive drug intake1.21.83.20.11.4-0.60.8-0.90.90.6-0.8-1.61.61.6-1.1-1.7-1.71.81.6-1.31.81.4-1.4-1.61.7
One hour access (shock baseline)0.30.82.51.6-1.1-1.41.3-1.21.21.3-1.20.8-0.7-0.5-1.00.30.4-0.3-0.2-0.7-0.40.6-0.5-0.30.3
Social response proportion0.50.61.5-1.20.31.0-1.11.1-1.1-1.21.2-0.10.0-0.11.00.30.3-0.2-0.20.9-0.1-0.80.80.7-0.6
Social responses1.31.72.8-1.4-0.31.5-1.41.3-1.3-1.51.60.7-0.8-0.91.71.11.2-1.1-1.21.7-0.7-1.71.61.6-1.4
Social time1.11.85.1-1.82.31.2-1.21.2-1.2-1.21.3-2.01.91.70.4-1.5-1.31.41.30.11.70.1-0.3-0.60.6
Soleus weight2.16.09.8-1.6-1.42.2-2.32.2-2.2-2.22.32.0-2.0-2.32.82.52.6-2.5-2.52.9-2.8-2.92.92.8-3.1
Bone: stiffness0.30.62.2-1.50.31.1-1.11.1-1.1-1.00.9-0.00.0-0.11.00.30.4-0.3-0.30.9-0.5-0.80.80.5-0.5
Tibialis anterior weight0.41.22.3-0.1-1.00.8-0.60.5-0.5-0.50.51.3-1.2-1.31.01.41.4-1.4-1.31.2-1.3-1.31.21.3-1.5
Time to tail flick, vehicle, before self-admin0.20.20.50.6-0.4-0.70.4-0.30.20.5-0.20.1-0.0-0.0-0.6-0.1-0.40.30.4-0.7-0.60.6-0.5-0.50.3
Time to tail flick, vehicle, after self-admin0.20.51.10.9-1.0-1.01.0-1.01.00.9-0.90.7-0.7-0.6-0.70.40.1-0.2-0.3-0.5-0.60.4-0.3-0.20.2
Time to tail flick, test, before self-admin1.01.12.0-0.2-1.10.4-0.60.6-0.6-0.70.51.3-1.3-1.30.91.31.3-1.2-1.31.0-1.4-1.11.11.2-1.4
Time to tail flick, test, after self-admin0.91.01.7-0.2-0.90.5-0.60.6-0.6-0.50.61.0-1.1-1.10.91.21.2-1.3-1.21.1-0.9-1.11.11.3-1.3
Delta time to tail flick, vehicle, before/after SA0.30.31.20.3-0.5-0.30.7-0.91.00.6-1.10.5-0.5-0.5-0.20.40.4-0.4-0.60.10.2-0.10.10.20.2
Delta time to tail flick, test, before/after SA0.10.20.7-0.20.80.3-0.20.2-0.2-0.00.2-0.70.70.60.0-0.6-0.50.40.5-0.00.80.1-0.1-0.20.3
Tibia length1.33.78.32.9-0.8-2.82.8-2.72.82.7-2.90.1-0.00.3-2.5-0.7-0.80.80.8-2.11.12.0-2.0-1.61.6
Ambulatory time before self-admin0.10.41.3-0.51.10.6-0.60.6-0.6-0.50.5-1.01.00.90.1-0.8-0.80.90.8-0.10.70.2-0.2-0.40.4
Ambulatory time after self-admin2.23.66.30.52.0-1.40.6-0.30.30.9-0.4-2.32.32.4-1.7-2.5-2.32.52.5-2.02.32.1-2.2-2.22.0
Bone: tissue strength1.81.93.60.11.4-0.60.6-0.50.60.5-0.8-1.61.71.7-1.1-1.7-1.81.91.8-1.41.51.5-1.5-1.71.6
Total heroin consumption0.00.00.10.1-0.0-0.3-0.00.1-0.1-0.10.1-0.0-0.00.0-0.1-0.0-0.00.2-0.1-0.10.00.1-0.1-0.0-0.0
Bone: trabecular number0.51.02.2-0.81.40.3-0.60.8-0.8-0.50.7-1.41.51.3-0.1-1.2-1.41.41.5-0.80.10.8-0.7-1.10.8
Bone: trabecular spacing0.40.61.81.0-0.6-1.01.3-1.41.41.2-1.30.4-0.4-0.2-0.90.10.2-0.2-0.2-0.50.70.4-0.5-0.20.5
Bone: trabecular thickness0.30.41.3-0.60.20.8-1.01.1-1.1-0.91.1-0.00.1-0.10.80.2-0.00.0-0.00.5-0.9-0.50.50.3-0.8
Bone: trabecular tissue density1.42.55.1-2.30.52.1-2.12.0-2.0-2.21.90.1-0.2-0.52.10.81.0-1.0-1.12.0-0.6-1.91.81.5-1.5
Water consumed over 24 hours0.10.30.9-0.10.70.3-0.60.6-0.7-0.61.0-0.70.70.60.2-0.5-0.50.50.6-0.10.20.2-0.1-0.2-0.1
Number of responses in last shaping day1.11.42.3-1.1-0.31.2-1.41.5-1.5-1.41.50.7-0.7-0.81.41.01.0-1.0-0.91.3-1.2-1.31.31.2-1.3