Ociad2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Ociad2 0.15 0.24 6.5e-04 0.04 0.02 0.04 0.03 7.8e-05 2.2e-03 3.2e-05 1.2e-04
2 BLA mRNA stability Ociad2 0.26 0.41 3.2e-04 0.04 0.04 0.04 0.04 4.3e-03 2.7e-03 3.5e-03 5.3e-03
3 NAcc mRNA stability Ociad2 0.04 0.04 7.6e-05 0.03 0.03 0.03 0.03 1.4e-04 6.7e-05 1.8e-04 1.8e-04
4 Liver alternative polyA XM_039091555.1 0.13 0.1 1.7e-14 0.09 0.12 0.11 0.11 2.7e-10 6.8e-13 9.4e-12 3.7e-12
5 Liver alternative polyA XM_039091553.1 0.12 0.1 2.8e-13 0.09 0.11 0.1 0.1 7.5e-10 7.8e-12 5.8e-11 4.8e-11
6 Liver mRNA stability Ociad2 0.1 0.09 1.0e-10 0.06 0.08 0.07 0.07 2.7e-07 7.0e-09 1.6e-08 4.4e-08
7 Adipose alternative polyA XM_039091553.1 0.04 0.03 3.8e-04 0.02 0.02 0.02 0.02 2.6e-03 1.6e-03 4.5e-03 2.3e-03
8 Adipose alternative polyA XM_039091555.1 0.04 0.04 3.1e-04 0.02 0.02 0.02 0.02 2.4e-03 1.4e-03 4.1e-03 2.1e-03
9 Liver intron excision ratio chr14_34885611_34888103 0.03 0.03 1.3e-03 0.01 0.02 0.01 0.01 7.1e-03 5.1e-03 1.9e-02 1.0e-02
10 Liver gene expression Ociad2 0.03 0.03 1.0e-03 0.02 0.02 0.01 0.02 2.2e-03 1.4e-03 2.2e-02 1.7e-03
11 Brain mRNA stability Ociad2 0.02 0.02 9.4e-03 0.01 0.01 0 0.01 3.9e-02 4.9e-02 1.7e-01 7.7e-02
12 PL isoform ratio XM_039091554.1 0.04 0.04 1.0e-04 0.04 0.04 0.04 0.04 2.3e-05 6.7e-05 3.5e-05 4.8e-05
13 Brain alternative polyA XM_039091553.1 0.03 0.03 1.3e-03 0.03 0.03 0.03 0.03 5.0e-04 8.1e-04 5.7e-04 6.1e-04
14 Brain alternative polyA XM_039091555.1 0.03 0.03 1.4e-03 0.03 0.03 0.03 0.03 4.9e-04 7.9e-04 5.5e-04 5.6e-04
15 Adipose gene expression Ociad2 0.04 0.04 2.4e-04 0.03 0.02 0.01 0.02 4.1e-04 6.0e-03 8.8e-03 2.7e-03
16 Adipose mRNA stability Ociad2 0.05 0.05 1.9e-05 0.04 0.03 0.04 0.04 2.8e-05 1.0e-04 6.2e-05 7.6e-05
17 Liver isoform ratio XM_039091555.1 0.02 0.02 8.1e-03 0.01 0.01 0.01 0.01 7.0e-03 6.8e-02 2.9e-02 4.5e-02
18 Liver intron excision ratio chr14_34885611_34886858 0.03 0.03 2.8e-03 0.01 0 0 0 6.0e-02 7.9e-02 3.2e-01 1.2e-01
19 NAcc isoform ratio XM_039091554.1 0.04 0.04 8.8e-05 0.04 0.04 0.04 0.04 2.5e-05 4.7e-05 3.9e-05 4.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density1.72.811.3-3.41.21.41.5-1.51.5-1.51.51.51.5-1.61.61.6-1.6-1.6-1.6-1.61.61.6
Area under the delay curve0.90.91.2-0.91.11.01.0-1.01.0-1.01.01.01.0-1.01.01.0-1.0-1.0-1.0-1.01.01.0
BMI with tail1.65.144.7-6.71.41.61.6-1.61.6-1.61.61.61.6-1.91.91.8-1.8-1.8-1.8-1.81.81.8
BMI without tail1.02.09.8-3.11.21.31.3-1.31.3-1.31.31.31.3-1.21.21.2-1.2-1.2-1.2-1.21.21.2
Body weight0.31.115.6-3.90.50.60.6-0.60.6-0.60.60.60.6-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Weight adjusted by age2.42.84.6-0.1-2.1-1.8-1.81.8-1.81.8-1.8-1.8-1.81.5-1.5-1.51.51.61.61.6-1.6-1.6
Bone surface1.62.93.3-1.01.81.81.8-1.81.8-1.81.81.71.7-1.71.71.7-1.7-1.7-1.7-1.71.71.7
Bone volume1.83.05.6-2.41.61.71.7-1.71.7-1.71.71.71.7-1.71.71.7-1.7-1.7-1.7-1.71.71.7
Breakpoint value in progressive ratio session1.21.32.1-1.41.01.11.1-1.11.1-1.11.11.11.1-1.11.11.1-1.1-1.1-1.1-1.11.11.1
Number of licking bursts3.94.65.4-1.02.32.32.3-2.32.3-2.32.32.32.3-2.12.12.1-2.1-2.1-2.1-2.12.12.1
Context. condit. distance diff. score0.40.43.9-2.00.10.40.4-0.40.4-0.40.40.40.4-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Locomotion velocity, session 10.20.20.30.60.50.50.5-0.50.5-0.50.50.50.5-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Locomotion distance, session 10.20.30.3-0.50.50.50.5-0.50.5-0.50.50.50.5-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Locomotion velocity, session 20.00.00.10.40.10.10.1-0.10.1-0.10.10.10.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Locomotion distance, session 20.10.10.30.10.50.40.4-0.40.4-0.40.40.40.4-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Locomotion velocity, session 30.10.21.21.1-0.0-0.2-0.30.3-0.30.3-0.3-0.3-0.30.4-0.4-0.40.40.40.40.4-0.4-0.4
Locomotion distance, session 30.80.83.71.9-0.5-0.7-0.70.8-0.80.7-0.7-0.8-0.80.9-0.9-0.90.90.90.90.9-0.9-0.9
Stereotopy head waving bouts, day 31.21.56.0-2.50.71.01.0-1.01.0-1.01.01.01.0-1.21.21.2-1.2-1.2-1.2-1.21.21.2
Stereotopy head waving duration, day 30.60.73.6-1.90.30.60.7-0.70.7-0.70.70.70.7-0.80.80.8-0.8-0.8-0.8-0.80.80.8
Locomotion velocity, session 71.92.04.4-1.2-2.1-1.6-1.61.6-1.61.6-1.6-1.6-1.61.2-1.2-1.21.21.21.21.2-1.2-1.2
Locomotion distance, session 71.92.44.3-0.2-2.1-1.7-1.71.7-1.71.7-1.7-1.7-1.71.4-1.4-1.41.41.41.41.4-1.4-1.4
Stereotopy head waving bouts, day 70.20.22.5-1.6-0.7-0.4-0.40.4-0.40.4-0.4-0.4-0.40.2-0.2-0.20.20.20.20.2-0.2-0.2
Stereotopy head waving duration, day 70.30.40.8-0.6-0.9-0.7-0.70.7-0.70.7-0.7-0.7-0.70.5-0.5-0.50.50.50.50.5-0.5-0.5
Locomotion velocity, session 80.10.21.11.1-0.2-0.3-0.30.3-0.30.3-0.3-0.3-0.30.4-0.4-0.40.40.40.40.4-0.4-0.4
Locomotion distance, session 80.10.10.5-0.70.20.20.3-0.30.3-0.30.30.30.3-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Degree of sensitization distance0.60.63.6-1.9-1.4-0.9-0.80.8-0.80.8-0.8-0.8-0.80.4-0.4-0.40.40.40.40.4-0.4-0.4
Degree of sensitization stereotypy0.10.10.5-0.7-0.4-0.3-0.30.3-0.30.3-0.3-0.3-0.30.2-0.2-0.20.20.20.20.2-0.2-0.2
Conditioned locomotion1.31.57.9-2.81.51.21.2-1.21.2-1.21.21.21.2-0.90.90.9-0.9-0.9-0.9-0.90.90.9
Cocaine response after cond. corrected0.00.00.0-0.20.20.20.2-0.20.2-0.20.20.20.2-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Cocaine response after cond. not corrected0.40.41.6-1.30.50.60.6-0.60.6-0.60.60.60.6-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Cocaine response before conditioning0.10.10.7-0.8-0.20.10.1-0.10.1-0.10.10.10.1-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Saline control response0.60.811.5-3.40.60.50.5-0.50.5-0.50.50.50.5-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Bone: connectivity density0.91.51.9-1.01.41.31.3-1.31.3-1.31.31.31.3-1.21.21.2-1.2-1.2-1.2-1.21.21.2
Bone: cortical apparent density0.20.30.4-0.0-0.3-0.5-0.50.5-0.50.5-0.5-0.5-0.50.6-0.6-0.60.60.60.60.6-0.6-0.6
Bone: cortical area0.20.40.6-0.3-0.8-0.7-0.60.7-0.70.6-0.6-0.7-0.70.6-0.6-0.60.60.60.60.6-0.6-0.6
Bone: cortical porosity0.00.00.00.0-0.2-0.1-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.10.10.10.1-0.1-0.1
Bone: cortical porosity0.10.10.3-0.50.00.20.2-0.20.2-0.20.20.20.2-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Bone: cortical thickness0.30.40.60.8-0.6-0.7-0.70.7-0.70.7-0.7-0.7-0.70.7-0.7-0.70.70.70.70.7-0.7-0.7
Bone: cortical thickness1.72.012.6-3.51.31.21.2-1.21.2-1.21.21.21.2-1.21.21.2-1.2-1.2-1.2-1.21.21.2
Bone: cortical tissue density0.10.20.30.0-0.2-0.4-0.40.4-0.40.4-0.4-0.4-0.40.5-0.5-0.50.50.50.50.5-0.5-0.5
Condit. Reinf. active minus inactive responses0.10.11.2-1.1-0.3-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Condit. Reinf. active-inactive response ratio0.20.30.5-0.70.50.50.5-0.50.5-0.50.50.50.5-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Condit. Reinf. active responses0.30.32.9-1.70.20.40.4-0.40.4-0.40.40.40.4-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Condit. Reinf. inactive responses0.40.43.0-1.70.30.50.5-0.50.5-0.50.50.50.5-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Incentive salience index mean0.50.61.2-1.10.70.80.8-0.80.8-0.80.80.80.8-0.80.80.8-0.8-0.8-0.8-0.80.80.8
Condit. Reinf. lever presses3.24.25.0-1.52.22.12.1-2.12.1-2.12.12.12.1-2.02.02.0-2.0-2.0-2.0-2.02.02.0
Condit. Reinf. active minus inactive responses1.41.716.3-4.0-1.2-1.1-1.11.1-1.11.1-1.1-1.1-1.10.7-0.7-0.70.70.70.70.7-0.7-0.7
Condit. Reinf. active-inactive response ratio1.11.214.4-3.8-0.9-0.8-0.80.8-0.80.8-0.8-0.8-0.80.4-0.4-0.40.40.40.40.4-0.4-0.4
Condit. Reinf. active responses1.01.425.5-5.0-0.3-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Condit. Reinf. inactive responses1.21.512.6-3.50.91.01.0-1.01.0-1.01.01.01.0-0.90.90.9-0.9-0.9-0.9-0.90.90.9
Condit. Reinf. lever presses1.92.67.7-2.81.31.41.4-1.41.4-1.41.41.41.4-1.61.61.6-1.6-1.6-1.6-1.61.61.6
Condit. Reinf. lever reinforcers received0.71.018.1-4.3-0.00.00.1-0.10.1-0.10.10.10.1-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Conditioned reinforcement - actives3.53.55.4-0.22.32.12.0-2.02.0-2.02.02.02.0-1.81.81.8-1.8-1.8-1.8-1.81.81.8
Conditioned reinforcement - inactives0.20.22.11.40.0-0.2-0.20.2-0.20.2-0.2-0.2-0.20.4-0.4-0.40.40.40.40.4-0.4-0.4
Conditioned locomotion0.00.00.2-0.4-0.1-0.00.0-0.00.0-0.00.00.00.0-0.00.00.0-0.0-0.1-0.1-0.10.10.1
Patch foraging indifference point 0 sec1.01.63.9-2.01.31.31.3-1.31.3-1.31.31.31.3-1.11.11.2-1.2-1.2-1.2-1.21.21.2
Patch foraging indifference point AUC0.80.92.5-0.9-1.6-1.2-1.11.1-1.11.1-1.1-1.1-1.10.7-0.7-0.70.70.70.70.7-0.7-0.7
Delay disc. indifference point, 0s delay2.62.93.5-1.21.91.81.7-1.71.7-1.71.71.71.7-1.71.71.7-1.7-1.7-1.7-1.71.71.7
Delay disc. indifference point, 16s delay0.00.00.5-0.70.0-0.0-0.00.0-0.00.0-0.0-0.0-0.0-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Delay disc. indifference point, 2s delay2.73.03.2-1.71.81.71.7-1.71.7-1.71.71.71.7-1.71.71.7-1.7-1.7-1.7-1.71.71.7
Delay disc. indifference point, 24s delay1.41.32.6-1.61.11.11.1-1.11.1-1.11.11.11.1-1.21.21.2-1.2-1.2-1.2-1.21.21.2
Delay disc. indifference point, 4s delay3.13.34.3-1.12.11.91.9-1.91.9-1.91.91.91.9-1.81.81.8-1.8-1.8-1.8-1.81.81.8
Delay disc. indifference point, 8s delay0.90.91.4-0.31.21.11.0-1.01.0-1.01.01.01.0-0.90.90.9-0.9-0.9-0.9-0.90.90.9
Indifference point function ln k1.21.723.24.81.80.90.8-0.80.8-0.80.80.80.8-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Indifference point function log k1.21.723.24.81.80.90.8-0.80.8-0.80.80.80.8-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Patch foraging total patch changes 0 sec0.30.51.0-1.00.80.80.8-0.80.8-0.80.80.80.8-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Patch foraging total patch changes 12 sec0.40.54.5-2.1-1.2-0.7-0.60.6-0.60.6-0.6-0.6-0.60.3-0.3-0.30.30.30.30.3-0.3-0.3
Patch foraging total patch changes 18 sec1.11.417.5-4.2-0.20.40.5-0.50.5-0.50.50.50.5-0.80.80.9-0.9-0.9-0.9-0.90.90.9
Patch foraging total patch changes 24 sec0.81.017.3-4.2-0.5-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Patch foraging total patch changes 6 sec0.20.24.1-2.0-0.5-0.2-0.20.2-0.20.2-0.2-0.2-0.20.1-0.10.0-0.0-0.0-0.0-0.00.00.0
Patch foraging time to switch 0 sec0.50.79.8-3.1-0.30.30.3-0.30.3-0.30.30.30.3-0.70.70.6-0.6-0.6-0.6-0.60.60.6
Patch foraging water rate 0 sec2.74.34.81.8-1.9-2.1-2.12.1-2.12.1-2.1-2.1-2.12.2-2.2-2.12.12.12.12.1-2.1-2.1
Patch foraging water rate 12 sec0.30.42.5-1.60.40.50.6-0.60.6-0.60.60.60.6-0.40.40.5-0.5-0.5-0.5-0.50.50.5
Patch foraging water rate 18 sec0.30.45.0-2.20.30.40.4-0.40.4-0.40.40.40.4-0.20.20.3-0.3-0.3-0.3-0.30.30.3
Patch foraging water rate 24 sec0.70.94.52.1-0.2-0.6-0.70.7-0.70.7-0.7-0.7-0.71.1-1.1-1.01.01.01.01.0-1.0-1.0
Patch foraging water rate 6 sec0.60.97.92.80.3-0.4-0.50.5-0.50.5-0.5-0.5-0.51.0-1.0-0.90.90.90.90.9-0.9-0.9
Seeking ratio, delayed vs. immediate footshock2.12.43.80.1-2.0-1.7-1.61.6-1.61.6-1.6-1.6-1.61.5-1.5-1.41.41.51.51.5-1.5-1.5
Distance traveled before self-admin0.10.11.61.3-0.0-0.1-0.10.1-0.10.1-0.1-0.1-0.10.3-0.3-0.30.30.30.30.3-0.3-0.3
Distance traveled after self-admin0.60.610.3-3.2-0.9-0.3-0.30.3-0.30.3-0.3-0.3-0.3-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Extensor digitorum longus weight1.14.47.0-2.72.52.22.2-2.22.2-2.22.22.22.2-1.91.91.9-1.9-1.9-1.9-1.91.91.9
Bone: elastic displacement0.10.21.01.00.50.40.4-0.40.4-0.40.40.40.4-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Bone: elastic work0.00.10.5-0.70.20.20.2-0.20.2-0.20.20.20.2-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Bone: endosteal estimation1.22.68.3-2.91.31.51.5-1.51.5-1.51.51.51.5-1.61.61.6-1.6-1.6-1.6-1.61.61.6
Bone: endosteal perimeter0.20.42.3-1.50.30.50.5-0.50.5-0.50.50.50.5-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Epididymis fat weight0.10.22.2-1.5-0.5-0.00.0-0.00.0-0.00.00.00.0-0.50.50.3-0.3-0.3-0.3-0.30.30.3
Delta time in closed arm before/after self-admin0.30.34.3-2.1-0.10.10.2-0.20.2-0.20.20.20.2-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Delta time in open arm before/after self-admin1.11.01.01.0-1.0-1.0-1.01.0-1.01.0-1.0-1.0-1.01.0-1.0-1.01.01.01.01.0-1.0-1.0
Diff in mean of infusions in LGA sessions1.31.52.7-1.61.11.21.2-1.21.2-1.21.21.21.2-1.21.21.2-1.2-1.2-1.2-1.21.21.2
Delay discount exponential model param0.70.81.00.8-1.0-0.9-0.90.9-0.90.9-0.9-0.9-0.90.9-0.9-0.90.90.90.90.9-0.9-0.9
Extinction: sum of active levers before priming1.21.25.72.4-0.6-0.9-0.90.9-0.90.9-0.9-0.9-0.91.1-1.1-1.11.11.11.11.1-1.1-1.1
Active lever presses in extinction session 61.91.93.31.8-1.3-1.3-1.31.3-1.31.3-1.3-1.3-1.31.4-1.4-1.41.41.41.41.4-1.4-1.4
Bone: final force0.61.012.4-3.50.40.60.6-0.60.6-0.60.60.60.6-0.70.70.7-0.7-0.7-0.7-0.70.70.7
Bone: final moment0.30.57.7-2.8-0.00.20.2-0.20.2-0.20.20.20.2-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Food consumed during 24 hour testing period0.20.22.4-1.50.10.20.2-0.20.2-0.20.20.20.2-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Glucose0.71.04.0-2.00.90.90.9-0.90.9-0.90.90.90.9-0.90.90.9-0.9-0.9-0.9-0.90.90.9
Heart weight2.63.714.1-3.81.31.71.7-1.71.7-1.71.71.71.7-1.91.91.9-1.9-1.9-1.9-1.91.91.9
Delay discount hyperbolic model param1.21.31.61.0-1.3-1.2-1.11.1-1.11.1-1.1-1.1-1.11.1-1.1-1.11.11.11.11.1-1.1-1.1
Intermittent access intake day 1-15 change1.51.51.8-1.31.21.21.2-1.21.2-1.21.21.21.2-1.21.21.2-1.2-1.2-1.2-1.21.21.2
Intermittent access intake escalation1.61.51.7-1.01.31.31.3-1.31.3-1.31.31.31.3-1.21.21.2-1.2-1.2-1.2-1.21.21.2
Intermittent access intake escalation 20.30.30.7-0.80.40.50.5-0.50.5-0.50.50.50.5-0.60.60.6-0.6-0.5-0.5-0.50.50.5
Intermitt. access day 1 inactive lever presses0.50.50.8-0.0-0.9-0.8-0.80.8-0.80.8-0.8-0.8-0.80.7-0.7-0.70.70.70.70.7-0.7-0.7
Intermitt. access day 15 inactive lever presses0.10.21.8-1.3-0.6-0.3-0.30.3-0.30.3-0.3-0.3-0.30.1-0.1-0.10.10.10.10.1-0.1-0.1
Intermitt. access escalation Index3.53.133.65.80.1-0.8-0.90.9-0.90.9-0.9-0.9-0.91.5-1.5-1.51.51.41.41.4-1.4-1.4
Intermittent access day 1 total infusions0.10.12.21.50.3-0.0-0.10.1-0.10.1-0.1-0.1-0.10.2-0.2-0.20.20.20.20.2-0.2-0.2
Intermittent access day 15 total infusions0.40.40.6-0.40.70.70.7-0.70.7-0.70.70.70.7-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Intermittent access terminal intake (last 3 days)0.30.40.90.90.90.70.6-0.60.6-0.60.60.60.6-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Intermittent access total infusions0.30.30.70.30.80.70.6-0.60.6-0.60.60.60.6-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Intermittent access day 1 locomotion0.10.11.9-1.4-0.3-0.1-0.00.0-0.00.0-0.0-0.0-0.0-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Intermittent access day 15 total locomotion0.10.10.1-0.20.30.30.3-0.30.3-0.30.30.30.3-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Intermittent access total locomotion0.30.43.8-2.00.00.30.3-0.30.3-0.30.30.30.3-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Intermittent access standard deviation1.61.72.80.11.71.51.4-1.41.4-1.41.41.41.4-1.31.31.3-1.3-1.2-1.2-1.21.21.2
Left kidney weight4.412.479.5-8.92.62.82.9-2.92.9-2.92.92.92.9-3.13.13.0-3.0-3.0-3.0-3.03.03.0
Right kidney weight2.46.617.5-4.22.42.52.5-2.52.5-2.52.52.52.5-2.52.52.4-2.4-2.4-2.4-2.42.42.4
Cocaine induced anxiety0.20.34.3-2.1-0.6-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Post-drug Anxiety2.62.923.5-4.80.41.01.1-1.11.1-1.11.11.11.1-1.51.51.5-1.5-1.5-1.5-1.51.51.5
Baseline Anxiety2.62.75.9-2.41.41.61.6-1.61.6-1.61.61.61.6-1.61.61.6-1.6-1.6-1.6-1.61.61.6
Tail length0.20.55.52.3-0.2-0.4-0.40.4-0.40.4-0.4-0.4-0.40.6-0.6-0.50.50.50.50.5-0.5-0.5
Length with tail0.31.08.73.0-0.2-0.6-0.60.6-0.60.6-0.6-0.6-0.60.9-0.9-0.90.90.90.90.9-0.9-0.9
Length without tail0.20.50.70.3-0.6-0.7-0.70.7-0.70.7-0.7-0.7-0.70.8-0.8-0.80.80.80.80.8-0.8-0.8
Times rat made contact with spout3.03.43.8-1.31.92.01.9-1.91.9-1.91.91.91.9-1.81.81.8-1.8-1.8-1.8-1.81.81.8
Lifetime Intake0.20.30.4-0.30.60.60.5-0.50.5-0.50.50.50.5-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Liver weight, left0.81.33.0-0.61.71.41.3-1.31.3-1.31.31.31.3-0.90.90.9-0.9-0.9-0.9-0.90.90.9
Liver weight, right0.20.30.6-0.70.3-0.3-0.40.4-0.40.4-0.4-0.4-0.40.7-0.7-0.70.70.60.60.6-0.6-0.6
Locomotor activity0.20.46.4-2.5-0.5-0.2-0.10.1-0.10.1-0.1-0.1-0.1-0.20.20.1-0.1-0.1-0.1-0.10.10.1
Locomotor testing distance0.61.06.1-2.50.40.70.8-0.80.8-0.80.80.80.8-1.01.01.0-1.0-1.0-1.0-1.01.01.0
Locomotor testing rearing0.10.10.10.3-0.2-0.3-0.30.3-0.30.3-0.3-0.3-0.30.3-0.3-0.30.30.30.30.3-0.3-0.3
Locomotion in novel chamber0.00.10.8-0.9-0.10.00.1-0.10.1-0.10.10.10.1-0.10.10.1-0.1-0.2-0.2-0.20.20.2
Locomotion in novel chamber post-restriction0.20.30.30.5-0.4-0.6-0.60.6-0.60.6-0.6-0.6-0.60.5-0.5-0.50.50.50.50.5-0.5-0.5
Fecal boli incidents, locomotor time 10.20.21.9-1.40.10.30.3-0.30.3-0.30.30.30.3-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Change in fecal boli incidents, locomotor task0.10.12.21.50.30.00.0-0.00.0-0.00.00.00.00.2-0.2-0.20.20.20.20.2-0.2-0.2
Time >=10cm from walls, locomotor time 11.61.62.10.6-1.5-1.4-1.31.3-1.31.3-1.3-1.3-1.31.3-1.3-1.21.21.21.21.2-1.2-1.2
Bouts of movement, locomotor time 12.62.93.80.7-2.0-1.8-1.81.8-1.81.8-1.8-1.8-1.81.7-1.7-1.61.61.61.61.6-1.6-1.6
Total resting periods, locomotor time 12.93.24.30.7-2.1-1.9-1.91.9-1.91.9-1.9-1.9-1.91.8-1.8-1.71.71.71.71.7-1.7-1.7
Rest time, locomotor task time 10.50.51.1-0.5-1.0-0.8-0.80.8-0.80.8-0.8-0.8-0.80.6-0.6-0.70.70.60.60.6-0.6-0.6
Distance moved, locomotor task time 11.11.21.5-0.61.21.11.1-1.11.1-1.11.11.11.1-1.11.11.1-1.1-1.1-1.1-1.11.11.1
Vertical activity count, locomotor time 11.21.21.3-0.91.21.11.1-1.11.1-1.11.11.11.1-1.11.11.1-1.1-1.1-1.1-1.11.11.1
Time >=10cm from walls, locomotor time 20.80.81.4-0.2-1.2-1.0-1.01.0-1.01.0-1.0-1.0-1.00.8-0.8-0.80.80.80.80.8-0.8-0.8
Bouts of movement, locomotor time 20.10.10.10.3-0.2-0.2-0.20.2-0.20.2-0.2-0.2-0.20.2-0.2-0.20.20.20.20.2-0.2-0.2
Total resting periods, locomotor time 20.20.20.20.4-0.4-0.4-0.40.4-0.40.4-0.4-0.4-0.40.4-0.4-0.40.40.40.40.4-0.4-0.4
Rest time, locomotor task time 20.30.40.6-0.1-0.8-0.7-0.70.7-0.70.7-0.7-0.7-0.70.6-0.6-0.60.60.60.60.6-0.6-0.6
Distance moved, locomotor task time 21.11.32.4-1.61.01.11.1-1.11.1-1.11.11.11.1-1.11.11.1-1.1-1.1-1.1-1.11.11.1
Vertical activity count, locomotor time 20.40.40.7-0.90.60.60.6-0.60.6-0.60.60.60.6-0.70.70.7-0.7-0.7-0.7-0.70.70.7
Light reinforcement 10.10.10.60.80.70.40.3-0.30.3-0.30.30.30.3-0.10.1-0.00.00.00.00.0-0.0-0.0
Light reinforcement 20.00.00.00.20.00.10.1-0.10.1-0.10.10.10.1-0.20.20.0-0.0-0.0-0.0-0.00.00.0
Bone: marrow area1.22.77.7-2.81.31.51.5-1.51.5-1.51.51.51.5-1.61.61.6-1.6-1.6-1.6-1.61.61.6
Bone: maximum diameter0.10.10.20.3-0.4-0.4-0.40.4-0.40.4-0.4-0.4-0.40.4-0.4-0.40.40.40.40.4-0.4-0.4
Bone: maximum force0.61.113.6-3.70.40.50.6-0.60.6-0.60.60.60.6-0.70.70.7-0.7-0.7-0.7-0.70.70.7
Bone: maximum moment0.30.58.5-2.9-0.10.10.1-0.10.1-0.10.10.10.1-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Mean time between licks in bursts0.00.11.0-1.0-0.0-0.0-0.00.0-0.00.0-0.0-0.0-0.0-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Mean num. licks in bursts0.91.01.20.2-1.1-1.1-1.11.1-1.11.1-1.1-1.1-1.10.9-0.9-0.90.90.90.90.9-0.9-0.9
Cd content in liver0.80.88.62.9-0.6-0.6-0.60.6-0.60.6-0.6-0.6-0.60.7-0.7-0.70.70.70.70.7-0.7-0.7
Co content in liver0.20.20.30.6-0.4-0.4-0.40.4-0.40.4-0.4-0.4-0.40.5-0.5-0.50.50.50.50.5-0.5-0.5
Cu content in liver0.40.57.02.60.5-0.1-0.10.1-0.10.1-0.1-0.1-0.10.5-0.5-0.50.50.50.50.5-0.5-0.5
Fe content in liver0.10.10.3-0.5-0.3-0.3-0.30.3-0.30.3-0.3-0.3-0.30.3-0.3-0.30.30.30.30.3-0.3-0.3
K content in liver0.30.36.02.4-0.0-0.1-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.10.10.10.1-0.1-0.1
Mg content in liver2.12.23.21.8-1.7-1.5-1.51.5-1.51.5-1.5-1.5-1.51.4-1.4-1.41.41.41.41.4-1.4-1.4
Mn content in liver3.64.15.60.7-2.4-2.2-2.22.1-2.12.2-2.2-2.1-2.12.0-2.0-2.02.02.02.02.0-2.0-2.0
Na content in liver0.70.82.61.6-0.4-0.7-0.70.7-0.70.7-0.7-0.7-0.70.9-0.9-0.90.90.90.90.9-0.9-0.9
Rb content in liver0.91.17.12.7-0.5-0.8-0.80.8-0.80.8-0.8-0.8-0.81.0-1.0-1.01.01.01.01.0-1.0-1.0
Se content in liver9.011.051.47.2-2.9-3.0-3.03.0-3.03.0-3.0-3.0-3.02.9-2.9-2.92.92.92.92.9-2.9-2.9
Sr content in liver5.14.717.0-4.11.92.02.0-2.02.0-2.02.02.02.0-2.02.02.0-2.0-2.0-2.0-2.02.02.0
Zn content in liver0.50.54.62.10.50.50.5-0.50.5-0.50.50.50.5-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Bone: minimum diameter0.61.117.1-4.1-0.40.20.2-0.20.2-0.20.20.20.2-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Time in familiar zone, hab. session 10.10.11.0-1.0-0.4-0.2-0.10.1-0.10.1-0.1-0.1-0.1-0.00.00.0-0.0-0.0-0.0-0.00.00.0
Time in novel zone, hab. session 10.60.60.9-0.11.00.80.8-0.80.8-0.80.80.80.8-0.70.70.7-0.7-0.7-0.7-0.70.70.7
Total zone transitions, hab. session 10.00.00.10.30.30.10.1-0.10.1-0.10.10.10.1-0.00.00.0-0.0-0.0-0.0-0.00.00.0
Total locomotion distance, hab. session 10.10.22.4-1.5-0.10.10.1-0.10.1-0.10.10.10.1-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Locomotion velocity, hab. session 10.10.22.1-1.50.00.20.2-0.20.2-0.20.20.20.2-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Time in familiar zone, hab. session 20.00.10.7-0.8-0.3-0.2-0.10.1-0.10.1-0.1-0.1-0.10.0-0.0-0.00.00.00.00.0-0.0-0.0
Time in novel zone, hab. session 20.00.00.10.20.20.20.2-0.20.2-0.20.20.20.2-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Total zone transitions, hab. session 20.30.46.52.50.4-0.0-0.10.1-0.10.1-0.1-0.1-0.10.4-0.4-0.40.40.40.40.4-0.4-0.4
Total locomotion distance, hab. session 20.40.56.62.60.2-0.2-0.30.3-0.30.3-0.3-0.3-0.30.5-0.5-0.50.50.50.50.5-0.5-0.5
Locomotion velocity, hab. session 20.30.45.82.40.50.0-0.00.0-0.00.0-0.0-0.0-0.00.3-0.3-0.30.30.30.30.3-0.3-0.3
Novel to familiar place preference ratio0.30.31.0-1.0-0.8-0.6-0.60.6-0.60.6-0.6-0.6-0.60.4-0.4-0.40.40.40.40.4-0.4-0.4
Novelty place preference0.20.21.6-1.3-0.8-0.5-0.50.5-0.50.5-0.5-0.5-0.50.3-0.3-0.30.30.30.30.3-0.3-0.3
Time in novel zone, NPP test0.40.51.4-1.2-1.0-0.7-0.70.7-0.70.7-0.7-0.7-0.70.5-0.5-0.50.50.50.50.5-0.5-0.5
Total zone transitions, NPP test0.71.01.11.0-0.9-1.0-1.01.0-1.01.0-1.0-1.0-1.01.0-1.0-1.01.01.01.01.0-1.0-1.0
Total locomotion distance, NPP test0.00.00.1-0.3-0.1-0.1-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.10.10.10.1-0.1-0.1
Locomotion velocity, NPP test0.10.10.4-0.60.40.30.3-0.30.3-0.30.30.30.3-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Intraocular pressure1.42.03.0-0.3-1.7-1.5-1.51.5-1.51.5-1.5-1.5-1.51.3-1.3-1.31.31.41.41.4-1.4-1.4
Delta distance traveled before/after self-admin0.50.69.6-3.1-0.7-0.3-0.20.2-0.20.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Delta ambulatory time before/after self-admin0.70.87.2-2.7-1.4-0.8-0.80.8-0.80.8-0.8-0.8-0.80.4-0.4-0.40.40.40.40.4-0.4-0.4
Parametrial fat weight0.20.44.8-2.2-0.10.30.3-0.30.3-0.30.30.30.3-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Pavlov. Cond. lever latency1.11.41.60.8-1.3-1.2-1.21.2-1.21.2-1.2-1.2-1.21.2-1.2-1.21.21.21.21.2-1.2-1.2
Pavlov. Cond. magazine entry latency2.43.08.83.0-1.4-1.6-1.61.6-1.61.6-1.6-1.6-1.61.7-1.7-1.71.71.71.71.7-1.7-1.7
Pavlov. Cond. change in total contacts0.40.51.11.0-0.6-0.7-0.70.7-0.70.7-0.7-0.7-0.70.7-0.7-0.70.70.70.70.7-0.7-0.7
Pavlov. Cond. index score0.20.21.71.3-0.1-0.3-0.30.3-0.30.3-0.3-0.3-0.30.4-0.4-0.40.40.40.40.4-0.4-0.4
Pavlov. Cond. latency score0.10.11.41.20.0-0.1-0.10.1-0.10.1-0.1-0.1-0.10.2-0.2-0.20.20.20.20.2-0.2-0.2
Pavlov. Cond. lever contacts0.10.20.3-0.10.50.40.4-0.40.4-0.40.40.40.4-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Pavlov. Cond. magazine entry number1.92.310.4-3.20.91.21.3-1.31.3-1.31.31.31.3-1.51.51.5-1.5-1.5-1.5-1.51.51.5
Pavlov. Cond. intertrial magazine entries0.80.97.9-2.80.20.60.6-0.60.6-0.60.60.60.6-0.80.80.8-0.8-0.8-0.8-0.80.80.8
Pavlov. Cond. lever-magazine prob. diff.0.20.31.31.1-0.3-0.4-0.40.4-0.40.4-0.4-0.4-0.40.5-0.5-0.50.50.50.50.5-0.5-0.5
Pavlov. Cond. response bias0.20.21.01.0-0.2-0.3-0.30.3-0.30.3-0.3-0.3-0.30.4-0.4-0.40.40.40.40.4-0.4-0.4
Pavlov. Cond. lever latency0.20.30.4-0.1-0.3-0.5-0.50.5-0.50.5-0.5-0.5-0.50.6-0.6-0.60.60.60.60.6-0.6-0.6
Pavlov. Cond. magazine entry latency1.61.82.4-0.41.51.41.4-1.41.4-1.41.41.41.4-1.41.41.4-1.4-1.4-1.4-1.41.41.4
Pavlov. Cond. change in total contacts0.10.10.1-0.30.10.20.2-0.20.2-0.20.20.20.2-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Pavlov. Cond. index score1.72.22.5-1.11.31.41.4-1.41.4-1.41.41.41.4-1.61.61.6-1.6-1.6-1.6-1.61.61.6
Pavlov. Cond. latency score1.82.22.5-0.21.51.51.5-1.51.5-1.51.51.51.5-1.61.61.6-1.6-1.6-1.6-1.61.61.6
Pavlov. Cond. lever contacts0.20.30.5-0.20.30.50.5-0.50.5-0.50.50.50.5-0.70.70.7-0.7-0.7-0.7-0.70.70.7
Pavlov. Cond. magazine entry number1.51.92.01.0-1.4-1.4-1.31.3-1.31.3-1.3-1.3-1.31.4-1.4-1.41.41.41.41.4-1.4-1.4
Pavlov. Cond. intertrial magazine entries0.40.51.10.3-1.0-0.8-0.80.8-0.80.8-0.8-0.8-0.80.6-0.6-0.60.60.60.60.6-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.2.02.52.9-1.11.41.51.5-1.51.5-1.51.51.51.5-1.71.71.7-1.7-1.7-1.7-1.71.71.7
Pavlov. Cond. response bias0.20.31.0-1.00.30.30.3-0.30.3-0.30.30.30.3-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Time in closed arm before self-admin0.00.00.2-0.4-0.00.00.0-0.00.0-0.00.00.00.0-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Time in closed arm after self-admin1.11.110.2-3.20.20.60.6-0.60.6-0.60.60.60.6-0.90.90.9-0.9-0.9-0.9-0.90.90.9
Time in open arm before self-admin0.00.00.10.4-0.0-0.0-0.00.0-0.00.0-0.0-0.0-0.00.1-0.1-0.10.10.10.10.1-0.1-0.1
Time in open arm after self-admin0.70.81.41.2-0.8-0.8-0.80.8-0.80.8-0.8-0.8-0.80.9-0.9-0.90.90.90.90.9-0.9-0.9
Bone: periosteal estimation0.30.73.2-1.80.50.70.7-0.70.7-0.70.70.70.7-0.80.80.8-0.8-0.8-0.8-0.80.80.8
Bone: periosteal perimeter0.10.20.4-0.0-0.7-0.5-0.50.5-0.50.5-0.5-0.5-0.50.4-0.4-0.40.40.40.40.4-0.4-0.4
Bone: post-yield work0.20.35.6-2.4-0.3-0.1-0.10.1-0.10.1-0.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Progressive ratio test 1 active lever presses0.00.00.20.50.30.20.1-0.10.1-0.10.10.10.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Progressive ratio test 1 breakpoint0.10.10.40.60.40.30.2-0.20.2-0.20.20.20.2-0.10.10.1-0.1-0.1-0.1-0.10.10.1
Progressive ratio test 1 inactive lever presses0.91.010.03.21.60.90.8-0.80.8-0.80.80.80.8-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Progressive ratio test 2 active lever presses0.10.10.8-0.90.10.20.2-0.20.2-0.20.20.20.2-0.30.30.3-0.3-0.3-0.3-0.30.30.3
Progressive ratio test 2 breakpoint0.10.10.9-0.9-0.00.10.1-0.10.1-0.10.10.10.1-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Progressive ratio test 2 inactive lever presses0.40.42.31.5-0.3-0.5-0.50.5-0.50.5-0.5-0.5-0.50.6-0.6-0.60.60.60.60.6-0.6-0.6
Incentive Sensitization - Responses0.10.10.3-0.4-0.6-0.4-0.40.4-0.40.4-0.4-0.4-0.40.3-0.3-0.30.30.30.30.3-0.3-0.3
Incentive Sensitization - Breakpoint0.20.20.4-0.3-0.6-0.5-0.50.5-0.50.5-0.5-0.5-0.50.4-0.4-0.40.40.40.40.4-0.4-0.4
Sum of active levers in priming session hrs 5-60.20.10.91.0-0.2-0.3-0.30.3-0.30.3-0.3-0.3-0.30.4-0.4-0.40.40.40.40.4-0.4-0.4
Progressive ratio0.40.40.50.7-0.6-0.7-0.70.7-0.70.7-0.7-0.7-0.70.6-0.6-0.60.60.60.60.6-0.6-0.6
Food seeking constrained by brief footshock0.20.20.5-0.6-0.7-0.5-0.50.5-0.50.5-0.5-0.5-0.50.3-0.3-0.40.40.40.40.4-0.4-0.4
Seeking ratio, punishment vs. effort0.50.61.9-1.40.50.70.7-0.70.7-0.70.70.70.7-0.70.70.7-0.7-0.8-0.8-0.80.80.8
Retroperitoneal fat weight0.41.31.8-0.4-1.4-1.2-1.21.2-1.21.2-1.2-1.2-1.21.0-1.0-1.11.11.11.11.1-1.1-1.1
Reaction time number correct0.60.82.5-0.21.61.11.0-1.01.0-1.01.01.01.0-0.80.80.7-0.7-0.7-0.7-0.70.70.7
Reaction time mean minus median0.50.72.3-1.5-1.1-0.9-0.90.9-0.90.9-0.9-0.9-0.90.6-0.6-0.60.60.60.60.6-0.6-0.6
Reaction time mean minus median AUC0.60.82.0-1.4-1.3-1.0-1.01.0-1.01.0-1.0-1.0-1.00.6-0.6-0.70.70.70.70.7-0.7-0.7
Reaction time num false alarms2.33.223.4-4.80.81.21.2-1.21.2-1.21.21.21.2-1.61.61.7-1.7-1.7-1.7-1.71.71.7
Reaction time num false alarms AUC3.85.213.7-3.71.92.12.1-2.12.1-2.12.12.12.1-2.22.22.3-2.3-2.3-2.3-2.32.32.3
Reaction time trials correct on left0.60.82.5-0.21.61.11.0-1.01.0-1.01.01.01.0-0.80.80.7-0.7-0.7-0.7-0.70.70.7
Reaction time trials on left0.50.72.30.21.51.00.9-0.90.9-0.90.90.90.9-0.70.70.6-0.6-0.6-0.6-0.60.60.6
Reaction time mean1.01.311.0-3.3-1.1-1.0-1.01.0-1.01.0-1.0-1.0-1.00.8-0.8-0.80.80.80.80.8-0.8-0.8
Reaction time mean AUC1.21.611.0-3.3-1.5-1.2-1.11.1-1.11.1-1.1-1.2-1.20.9-0.9-0.90.90.90.90.9-0.9-0.9
Median of all reaction times0.81.19.2-3.0-1.0-0.9-0.90.9-0.90.9-0.9-0.9-0.90.8-0.8-0.80.80.80.80.8-0.8-0.8
Reaction time omissions3.34.535.46.0-0.8-1.4-1.51.5-1.51.5-1.5-1.5-1.51.9-1.9-1.91.91.91.91.9-1.9-1.9
Reaction time false alarm rate2.23.113.2-3.60.81.31.4-1.41.4-1.41.41.41.4-1.71.71.9-1.9-1.9-1.9-1.91.91.9
Reaction time premature initiation rate0.50.72.50.71.61.11.0-1.01.0-1.01.01.01.0-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Reaction time premature initiations0.81.24.40.82.11.41.3-1.31.3-1.31.31.31.3-0.70.70.6-0.6-0.6-0.6-0.60.60.6
Std. dev. reaction times0.30.54.5-2.1-0.8-0.6-0.60.6-0.60.6-0.6-0.6-0.60.3-0.3-0.40.40.40.40.4-0.4-0.4
Reaction time trials completed0.50.72.30.21.51.00.9-0.90.9-0.90.90.90.9-0.70.70.6-0.6-0.6-0.6-0.60.60.6
Reaction time trials AUC0.50.72.40.41.61.01.0-1.01.0-1.01.01.01.0-0.70.70.5-0.5-0.5-0.5-0.50.50.5
Run reversals in cocaine runway, females0.70.67.1-2.7-0.10.30.4-0.40.4-0.40.40.40.4-0.60.60.7-0.7-0.7-0.7-0.70.70.7
Run reversals in cocaine runway, males0.60.610.23.20.60.10.0-0.00.0-0.00.00.00.00.3-0.3-0.30.30.40.40.4-0.4-0.4
Latency to leave start box in cocaine runway0.30.30.60.3-0.8-0.6-0.60.6-0.60.6-0.6-0.6-0.60.5-0.5-0.60.60.60.60.6-0.6-0.6
Latency to leave start box in cocaine runway, F0.00.00.0-0.0-0.20.00.0-0.00.0-0.00.00.00.0-0.00.0-0.10.10.10.10.1-0.1-0.1
Latency to leave start box in cocaine runway, M0.30.30.30.4-0.6-0.6-0.60.6-0.60.6-0.6-0.6-0.60.5-0.5-0.50.50.50.50.5-0.5-0.5
Std. dev. time between licks in bursts0.20.20.20.2-0.5-0.5-0.50.5-0.50.5-0.5-0.5-0.50.4-0.4-0.40.40.40.40.4-0.4-0.4
Total sessions with >9 infusions0.10.22.5-1.6-0.5-0.2-0.20.2-0.20.2-0.2-0.2-0.2-0.00.00.0-0.0-0.0-0.0-0.00.00.0
Short access day 1 total inactive lever presses0.20.20.30.30.50.50.5-0.50.5-0.50.50.50.5-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Short access day 10 total inactive lever presses0.00.00.30.5-0.0-0.1-0.10.1-0.10.1-0.1-0.1-0.10.1-0.1-0.10.10.10.10.1-0.1-0.1
Short access day 1 total infusions0.60.71.3-0.4-1.1-0.9-0.90.9-0.90.9-0.9-0.9-0.90.8-0.8-0.80.80.70.70.7-0.7-0.7
Short access day 10 total infusions0.20.20.3-0.50.50.50.5-0.50.5-0.50.50.50.5-0.50.50.5-0.5-0.5-0.5-0.50.50.5
Short access total infusions0.00.00.2-0.40.10.10.1-0.10.1-0.10.10.10.1-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Short access day 1 locomotion1.11.21.50.7-1.2-1.2-1.21.2-1.21.2-1.2-1.2-1.21.1-1.1-1.11.11.11.11.1-1.1-1.1
Short access day 10 total locomotion0.50.64.4-2.10.20.50.5-0.50.5-0.50.50.50.5-0.70.70.7-0.7-0.7-0.7-0.70.70.7
Short access total locomotion0.10.11.0-1.0-0.2-0.0-0.00.0-0.00.0-0.0-0.0-0.0-0.10.10.1-0.1-0.1-0.1-0.10.10.1
One hour access (0.3 mA shock)1.72.02.6-0.81.61.51.5-1.51.5-1.51.51.51.5-1.41.41.4-1.4-1.4-1.4-1.41.41.4
Compulsive drug intake0.20.20.4-0.60.40.40.4-0.40.4-0.40.40.40.4-0.40.40.4-0.4-0.4-0.4-0.40.40.4
One hour access (shock baseline)0.20.21.1-1.10.20.30.3-0.30.3-0.30.30.30.3-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Social response proportion3.53.86.51.52.52.22.1-2.12.1-2.12.12.12.1-1.71.71.7-1.7-1.7-1.7-1.71.71.7
Social responses0.30.35.52.30.40.30.3-0.30.3-0.30.30.30.3-0.00.00.1-0.1-0.1-0.1-0.10.10.1
Social time4.76.26.6-0.92.52.62.6-2.62.6-2.62.62.62.6-2.52.52.6-2.6-2.6-2.6-2.62.62.6
Soleus weight0.00.10.6-0.70.3-0.1-0.20.2-0.20.2-0.2-0.2-0.20.4-0.4-0.40.40.40.40.4-0.4-0.4
Bone: stiffness0.30.47.8-2.8-0.4-0.2-0.20.2-0.20.2-0.2-0.2-0.20.0-0.0-0.00.00.00.00.0-0.0-0.0
Tibialis anterior weight0.20.61.40.81.20.90.8-0.80.8-0.80.80.80.8-0.60.60.6-0.6-0.6-0.6-0.60.60.6
Time to tail flick, vehicle, before self-admin0.60.66.9-2.6-1.1-0.6-0.50.5-0.50.5-0.5-0.5-0.50.2-0.2-0.20.20.20.20.2-0.2-0.2
Time to tail flick, vehicle, after self-admin0.30.30.6-0.3-0.8-0.6-0.60.6-0.60.6-0.6-0.6-0.60.5-0.5-0.50.50.50.50.5-0.5-0.5
Time to tail flick, test, before self-admin3.33.27.12.7-1.5-1.7-1.71.7-1.71.7-1.7-1.7-1.71.8-1.8-1.81.81.81.81.8-1.8-1.8
Time to tail flick, test, after self-admin0.00.00.10.30.10.10.1-0.10.1-0.10.10.10.1-0.00.00.0-0.0-0.0-0.0-0.00.00.0
Delta time to tail flick, vehicle, before/after SA0.20.23.01.70.1-0.2-0.20.2-0.20.2-0.2-0.2-0.20.4-0.4-0.40.40.40.40.4-0.4-0.4
Delta time to tail flick, test, before/after SA2.11.94.1-2.01.21.31.3-1.31.3-1.31.31.31.3-1.41.41.4-1.4-1.4-1.4-1.41.41.4
Tibia length0.41.220.6-4.5-0.8-0.4-0.40.4-0.40.4-0.4-0.4-0.40.1-0.1-0.10.10.10.10.1-0.1-0.1
Ambulatory time before self-admin0.10.10.20.50.40.30.3-0.30.3-0.30.30.30.3-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Ambulatory time after self-admin0.30.35.5-2.3-0.5-0.1-0.00.0-0.00.0-0.0-0.0-0.0-0.20.20.2-0.2-0.2-0.2-0.20.20.2
Bone: tissue strength1.00.91.11.0-0.9-1.0-1.01.0-1.01.0-1.0-1.0-1.01.0-1.0-1.01.01.01.01.0-1.0-1.0
Total heroin consumption1.01.29.33.1-0.3-0.7-0.70.7-0.70.7-0.7-0.7-0.71.0-1.0-1.01.01.01.01.0-1.0-1.0
Bone: trabecular number1.32.07.9-2.81.21.31.3-1.31.3-1.31.31.31.3-1.31.31.3-1.3-1.3-1.3-1.31.31.3
Bone: trabecular spacing1.01.32.20.6-1.5-1.3-1.21.2-1.21.2-1.2-1.2-1.21.0-1.0-1.01.01.01.01.0-1.0-1.0
Bone: trabecular thickness2.02.44.00.02.01.71.7-1.71.7-1.71.71.71.7-1.41.41.4-1.4-1.4-1.4-1.41.41.4
Bone: trabecular tissue density0.30.41.6-1.3-0.7-0.6-0.60.6-0.60.6-0.6-0.6-0.60.5-0.5-0.50.50.50.50.5-0.5-0.5
Water consumed over 24 hours0.40.51.91.40.80.80.8-0.80.8-0.80.80.80.8-0.40.40.4-0.4-0.4-0.4-0.40.40.4
Number of responses in last shaping day1.61.72.00.8-1.4-1.4-1.31.3-1.31.3-1.3-1.3-1.31.3-1.3-1.31.31.31.31.3-1.3-1.3