Nos2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC alternative TSS XM_039085203.2 0.12 0.11 7.9e-04 0.05 0.06 0.06 0.06 4.8e-03 1.8e-03 1.2e-03 2.0e-03
2 IC alternative TSS NM_012611.3 0.12 0.11 7.3e-04 0.05 0.06 0.06 0.06 4.7e-03 1.7e-03 1.3e-03 1.9e-03
3 BLA alternative polyA NM_012611.3 0.14 0.1 1.7e-07 0.12 0.13 0.13 0.13 3.9e-07 3.4e-07 2.1e-07 2.8e-07
4 PL alternative polyA NM_012611.3 0.17 0.11 0.0e+00 0.22 0.21 0.22 0.22 9.5e-24 9.6e-23 5.0e-24 6.5e-24
5 BLA alternative polyA XM_039085203.2 0.14 0.1 4.9e-07 0.12 0.12 0.12 0.12 1.2e-06 7.7e-07 6.3e-07 9.2e-07
6 PL alternative polyA XM_039085203.2 0.17 0.11 0.0e+00 0.22 0.21 0.22 0.22 7.1e-24 2.7e-22 4.5e-24 9.3e-24
7 Brain alternative polyA XM_039085203.2 0.28 0.18 0.0e+00 0.2 0.19 0.21 0.21 2.0e-18 1.2e-17 4.4e-19 1.4e-19
8 OFC alternative polyA NM_012611.3 0.24 0.15 1.1e-04 0.07 0.11 0.04 0.11 9.0e-03 1.8e-03 3.4e-02 1.6e-03
9 NAcc gene expression Nos2 0.1 0.12 2.4e-03 0.01 0.01 0.02 0.01 4.9e-03 3.2e-03 6.1e-04 7.5e-03
10 BLA gene expression Nos2 0.26 0.16 1.2e-10 0.15 0.16 0.16 0.16 2.3e-08 1.2e-08 7.3e-09 1.4e-08
11 OFC alternative polyA XM_039085203.2 0.23 0.14 9.3e-05 0.06 0.11 0.03 0.11 1.5e-02 1.8e-03 6.8e-02 1.3e-03
12 IC gene expression Nos2 0.33 0.2 1.5e-11 0.18 0.19 0.18 0.18 7.0e-08 2.0e-08 3.6e-08 5.0e-08
13 NAcc alternative polyA XM_039085203.2 0.02 0.02 1.5e-04 0.02 0.02 0.01 0.02 9.3e-04 8.2e-04 1.9e-03 1.1e-03
14 NAcc alternative polyA NM_012611.3 0.02 0.02 2.8e-04 0.01 0.02 0.01 0.01 2.3e-03 1.5e-03 5.0e-03 2.7e-03
15 BLA alternative TSS XM_039085203.2 0.1 0.08 2.1e-05 0.06 0.08 0.07 0.07 4.8e-04 3.8e-05 1.3e-04 1.9e-04
16 BLA alternative TSS NM_012611.3 0.1 0.08 2.1e-05 0.06 0.08 0.07 0.07 4.7e-04 3.8e-05 1.3e-04 1.9e-04
17 PL alternative TSS NM_012611.3 0.04 0.04 8.3e-05 0.03 0.04 0.04 0.04 3.9e-04 5.3e-05 6.8e-05 5.9e-05
18 PL alternative TSS XM_039085203.2 0.04 0.04 1.3e-04 0.03 0.04 0.04 0.04 5.2e-04 7.2e-05 9.2e-05 8.2e-05
19 Adipose alternative TSS NM_012611.3 0.04 0.04 8.1e-04 0.01 0.01 0.01 0.01 1.6e-02 1.4e-02 2.5e-02 4.5e-02
20 Adipose alternative TSS XM_039085203.2 0.04 0.04 7.1e-04 0.01 0.01 0.01 0.01 1.7e-02 1.3e-02 2.1e-02 4.2e-02
21 PL gene expression Nos2 0.17 0.11 0.0e+00 0.19 0.2 0.2 0.2 2.0e-20 4.1e-21 2.7e-21 1.1e-21
22 IC alternative polyA XM_039085203.2 0.13 0.11 2.7e-04 0.05 0.06 0.06 0.05 4.9e-03 2.0e-03 1.8e-03 2.6e-03
23 IL gene expression Nos2 0.36 0.32 5.0e-03 0.14 0.11 0.14 0.15 2.7e-04 1.3e-03 2.7e-04 2.3e-04
24 pVTA gene expression Nos2 0.15 0.18 2.2e-03 0.04 0.02 0.03 0.03 3.2e-04 1.6e-02 3.1e-03 1.5e-03
25 Adipose gene expression Nos2 0.02 0.02 7.7e-03 0.01 0.01 0.01 0.01 1.6e-02 1.7e-02 3.7e-02 3.2e-02
26 Brain gene expression Nos2 0.37 0.22 1.5e-12 0.13 0.14 0.15 0.14 6.2e-12 1.2e-12 8.2e-14 7.1e-13

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density2.23.85.42.2-2.31.91.9-1.9-1.9-1.91.9-1.5-1.8-1.9-1.9-1.91.91.9-1.9-1.81.8-1.91.9-1.8-2.3-2.3-2.3-2.0-1.8
Area under the delay curve0.60.71.2-0.50.5-1.0-0.71.00.70.6-0.70.80.90.50.90.9-0.9-0.90.90.9-0.90.9-0.91.00.10.60.60.91.1
BMI with tail2.07.013.62.4-2.43.02.8-2.9-2.8-2.92.7-3.7-2.9-2.6-2.6-2.62.62.6-2.6-2.72.7-2.62.6-2.6-1.8-1.6-1.6-2.7-2.7
BMI without tail1.85.59.22.2-2.22.62.6-2.6-2.6-2.52.4-3.0-2.5-2.5-2.3-2.42.42.4-2.4-2.42.4-2.32.3-2.3-1.9-1.5-1.5-2.4-2.1
Body weight3.013.015.33.9-3.93.73.6-3.7-3.6-3.63.6-3.1-3.6-3.6-3.6-3.63.63.6-3.6-3.53.5-3.63.6-3.4-3.8-3.7-3.7-3.6-3.3
Weight adjusted by age0.10.21.5-0.20.20.40.5-0.3-0.6-0.60.4-0.6-0.3-0.6-0.1-0.10.10.1-0.1-0.20.3-0.00.1-0.30.51.21.2-0.10.1
Bone surface1.52.85.01.6-1.61.81.7-1.7-1.7-1.81.6-2.2-1.7-1.6-1.7-1.71.71.7-1.7-1.71.7-1.71.7-1.5-1.3-1.2-1.2-1.9-1.8
Bone volume1.42.63.01.7-1.71.71.6-1.6-1.7-1.71.6-1.6-1.6-1.6-1.6-1.61.61.6-1.6-1.61.6-1.61.6-1.5-1.6-1.4-1.4-1.7-1.5
Breakpoint value in progressive ratio session0.30.32.20.7-0.70.30.1-0.3-0.1-0.30.40.2-0.4-0.0-0.5-0.40.40.4-0.4-0.30.3-0.50.5-0.5-0.6-1.5-1.5-0.5-0.7
Number of licking bursts0.50.82.3-1.31.2-0.8-1.00.81.00.9-0.90.40.81.10.70.7-0.7-0.70.70.7-0.60.7-0.70.61.51.01.00.60.4
Context. condit. distance diff. score0.60.70.90.9-0.90.80.9-0.8-0.9-1.00.9-0.6-0.7-0.9-0.8-0.80.80.8-0.8-0.80.8-0.80.8-0.8-0.9-0.8-0.8-0.9-0.7
Locomotion velocity, session 12.22.33.41.4-1.41.51.4-1.6-1.4-1.31.4-1.6-1.6-1.4-1.6-1.61.61.6-1.6-1.61.6-1.61.6-1.4-1.3-1.4-1.4-1.9-1.6
Locomotion distance, session 10.20.31.20.0-0.00.40.3-0.5-0.20.00.2-1.1-0.6-0.2-0.5-0.60.60.6-0.6-0.60.6-0.50.5-0.40.2-0.1-0.1-0.9-0.8
Locomotion velocity, session 20.00.00.40.0-0.00.20.2-0.3-0.2-0.00.0-0.7-0.3-0.0-0.1-0.10.10.1-0.1-0.10.1-0.10.1-0.10.10.00.0-0.1-0.2
Locomotion distance, session 21.31.86.50.9-0.91.51.4-1.5-1.3-1.21.2-2.5-1.6-1.0-1.3-1.31.31.3-1.3-1.41.4-1.31.3-1.4-0.2-0.7-0.6-1.3-1.6
Locomotion velocity, session 33.43.94.9-2.22.2-2.0-2.02.02.01.8-2.11.51.92.22.02.0-2.0-2.02.02.0-2.01.9-1.92.02.22.02.01.41.4
Locomotion distance, session 30.40.40.7-0.80.8-0.6-0.70.60.70.6-0.70.60.60.70.60.6-0.6-0.60.60.6-0.60.6-0.60.70.80.90.90.20.4
Stereotopy head waving bouts, day 30.00.00.10.1-0.1-0.00.10.0-0.1-0.20.10.2-0.0-0.0-0.0-0.00.00.0-0.0-0.00.0-0.00.0-0.00.00.00.0-0.3-0.2
Stereotopy head waving duration, day 30.70.91.1-0.90.9-1.0-1.01.01.00.8-0.91.01.01.01.01.0-1.0-1.01.01.0-1.01.0-1.00.90.80.70.70.80.8
Locomotion velocity, session 70.10.10.40.3-0.30.40.5-0.3-0.5-0.60.3-0.1-0.3-0.5-0.3-0.30.30.3-0.3-0.30.3-0.30.3-0.2-0.30.30.3-0.3-0.1
Locomotion distance, session 70.20.30.50.5-0.50.60.7-0.6-0.7-0.70.6-0.3-0.5-0.6-0.5-0.50.60.6-0.6-0.60.6-0.50.5-0.5-0.4-0.1-0.1-0.6-0.3
Stereotopy head waving bouts, day 70.60.71.11.0-1.00.80.9-0.8-0.9-1.00.9-0.7-0.8-0.8-0.8-0.70.70.7-0.7-0.70.7-0.80.8-0.8-0.9-1.0-1.0-0.7-0.7
Stereotopy head waving duration, day 70.20.20.60.7-0.70.40.5-0.4-0.5-0.60.5-0.3-0.4-0.4-0.4-0.40.40.4-0.4-0.30.3-0.40.4-0.4-0.7-0.8-0.8-0.3-0.3
Locomotion velocity, session 80.10.10.30.1-0.10.20.2-0.2-0.1-0.20.2-0.3-0.2-0.1-0.3-0.30.30.3-0.3-0.30.3-0.30.3-0.20.1-0.1-0.1-0.5-0.6
Locomotion distance, session 80.81.12.10.9-0.81.11.1-1.1-1.1-1.11.1-1.5-1.2-0.9-1.1-1.11.11.1-1.1-1.11.1-1.11.1-1.1-0.4-0.7-0.6-1.2-1.3
Degree of sensitization distance2.82.93.91.9-1.91.81.9-1.8-1.9-1.91.9-1.3-1.7-2.0-1.7-1.71.71.7-1.7-1.61.6-1.61.6-1.8-1.9-1.6-1.6-1.3-1.3
Degree of sensitization stereotypy0.60.71.31.0-1.00.80.8-0.8-0.8-0.80.9-0.8-0.8-0.7-0.8-0.70.70.7-0.7-0.70.7-0.80.8-0.8-0.9-1.1-1.1-0.6-0.7
Conditioned locomotion2.12.44.7-1.91.9-1.5-1.61.51.61.6-1.60.31.41.71.51.5-1.5-1.51.51.4-1.41.4-1.41.42.21.81.81.10.7
Cocaine response after cond. corrected1.62.03.91.2-1.21.51.5-1.5-1.5-1.41.4-2.0-1.5-1.3-1.4-1.41.41.4-1.4-1.51.5-1.41.4-1.5-0.7-0.9-0.9-1.5-1.6
Cocaine response after cond. not corrected2.32.74.61.5-1.51.71.8-1.8-1.7-1.61.6-2.1-1.7-1.5-1.6-1.71.71.7-1.7-1.71.7-1.71.7-1.7-1.0-1.3-1.3-1.6-1.8
Cocaine response before conditioning0.20.20.40.6-0.60.50.5-0.5-0.5-0.40.4-0.4-0.4-0.4-0.4-0.40.40.4-0.4-0.40.4-0.40.4-0.4-0.6-0.6-0.6-0.2-0.3
Saline control response0.00.00.1-0.20.2-0.1-0.10.10.10.1-0.2-0.10.20.10.20.2-0.2-0.10.10.1-0.10.2-0.10.10.20.40.40.30.1
Bone: connectivity density3.55.57.02.5-2.52.32.3-2.3-2.3-2.42.3-2.2-2.3-2.3-2.4-2.42.42.3-2.3-2.32.3-2.42.4-2.2-2.2-2.3-2.3-2.6-2.5
Bone: cortical apparent density0.60.81.5-0.70.7-1.0-0.91.00.90.9-0.81.20.90.60.90.9-0.9-0.90.90.9-0.90.9-0.90.80.30.50.51.01.1
Bone: cortical area1.21.93.7-1.71.7-1.3-1.41.31.31.2-1.50.61.31.31.41.3-1.3-1.31.31.2-1.21.3-1.31.51.51.91.91.01.1
Bone: cortical porosity0.10.10.40.3-0.30.50.5-0.5-0.5-0.50.4-0.4-0.3-0.6-0.4-0.40.40.4-0.4-0.40.4-0.30.3-0.3-0.30.30.3-0.10.0
Bone: cortical porosity0.10.10.20.1-0.10.30.3-0.3-0.4-0.30.2-0.3-0.1-0.4-0.2-0.20.20.2-0.2-0.30.3-0.20.2-0.2-0.10.50.50.10.1
Bone: cortical thickness2.84.75.7-2.32.3-2.2-2.22.22.12.0-2.22.12.22.02.22.2-2.2-2.22.22.1-2.12.2-2.22.31.82.42.42.02.2
Bone: cortical thickness0.20.20.6-0.70.7-0.4-0.50.40.50.5-0.50.40.40.40.30.3-0.3-0.30.30.3-0.30.3-0.30.40.70.70.80.20.2
Bone: cortical tissue density0.30.51.1-0.50.5-0.8-0.70.80.70.7-0.61.10.70.40.70.7-0.7-0.70.70.7-0.70.7-0.70.60.10.30.30.80.9
Condit. Reinf. active minus inactive responses0.80.91.1-0.90.9-1.0-1.01.01.00.9-1.00.81.01.01.01.0-1.0-1.01.01.0-1.01.0-1.01.00.60.60.61.01.0
Condit. Reinf. active-inactive response ratio0.20.20.3-0.50.5-0.5-0.60.60.50.4-0.50.40.60.50.50.5-0.5-0.50.50.4-0.40.5-0.50.60.50.60.60.40.5
Condit. Reinf. active responses0.00.00.1-0.10.1-0.2-0.20.10.20.1-0.2-0.30.00.20.10.1-0.1-0.10.10.1-0.10.1-0.10.2-0.0-0.1-0.10.10.0
Condit. Reinf. inactive responses0.40.41.20.6-0.60.70.7-0.7-0.7-0.60.6-1.1-0.8-0.6-0.6-0.60.60.6-0.6-0.60.6-0.70.7-0.7-0.4-0.5-0.5-0.6-0.8
Incentive salience index mean0.20.30.4-0.50.5-0.6-0.60.60.50.4-0.6-0.20.50.60.60.6-0.6-0.60.60.6-0.60.6-0.60.60.50.50.50.50.5
Condit. Reinf. lever presses0.20.31.40.6-0.60.50.6-0.5-0.7-0.80.5-1.2-0.6-0.5-0.4-0.40.40.4-0.4-0.40.4-0.40.4-0.3-0.6-0.4-0.4-0.5-0.4
Condit. Reinf. active minus inactive responses0.81.11.7-1.11.1-1.2-1.21.11.31.3-1.11.01.11.31.01.0-1.0-1.01.01.0-1.01.0-1.00.91.10.50.50.90.8
Condit. Reinf. active-inactive response ratio0.80.91.6-0.80.8-1.1-1.21.01.21.2-1.01.00.91.20.91.0-1.0-1.01.01.0-1.00.9-0.90.80.80.10.10.90.7
Condit. Reinf. active responses0.50.71.0-0.90.9-1.0-1.00.91.00.9-0.90.90.91.00.80.8-0.8-0.80.80.9-0.90.8-0.80.81.00.60.60.80.8
Condit. Reinf. inactive responses0.00.00.4-0.20.2-0.10.10.1-0.1-0.2-0.0-0.00.1-0.10.10.0-0.0-0.00.0-0.00.00.1-0.10.10.20.60.60.00.3
Condit. Reinf. lever presses2.63.65.0-1.91.9-2.0-2.12.02.22.1-2.01.61.92.21.91.9-1.9-1.91.91.9-2.01.9-1.91.81.91.31.21.81.5
Condit. Reinf. lever reinforcers received0.81.11.6-1.11.1-1.2-1.21.21.21.2-1.11.01.11.31.01.0-1.0-1.01.01.0-1.01.0-1.01.01.20.80.80.90.9
Conditioned reinforcement - actives0.20.40.60.6-0.60.60.6-0.6-0.6-0.70.6-0.8-0.6-0.6-0.7-0.70.70.7-0.7-0.70.7-0.70.7-0.6-0.4-0.5-0.5-0.7-0.7
Conditioned reinforcement - inactives0.20.31.20.2-0.20.50.5-0.5-0.5-0.30.3-1.1-0.5-0.5-0.5-0.60.60.6-0.6-0.60.6-0.60.6-0.4-0.10.10.1-0.6-0.6
Conditioned locomotion0.70.92.60.7-0.71.01.1-1.0-1.1-1.21.1-1.6-1.0-0.9-0.9-0.90.90.9-0.9-1.01.0-0.90.9-1.0-0.1-0.2-0.1-1.0-1.0
Patch foraging indifference point 0 sec0.51.02.2-1.01.0-1.1-1.21.11.21.0-1.01.51.01.11.01.0-1.0-1.01.01.0-1.00.9-0.91.10.90.80.70.80.8
Patch foraging indifference point AUC2.23.25.2-2.12.1-1.9-2.01.92.12.0-1.91.01.72.11.81.8-1.8-1.81.81.7-1.71.7-1.71.62.31.71.71.41.1
Delay disc. indifference point, 0s delay0.60.71.3-1.01.0-0.8-0.90.80.90.8-0.80.40.70.90.80.8-0.8-0.70.70.7-0.70.8-0.80.71.11.01.00.90.8
Delay disc. indifference point, 16s delay0.20.20.80.2-0.2-0.5-0.20.50.10.1-0.20.90.5-0.10.50.5-0.5-0.50.50.6-0.60.5-0.50.5-0.7-0.1-0.10.60.9
Delay disc. indifference point, 2s delay2.12.33.1-1.31.3-1.6-1.61.71.61.5-1.51.81.61.51.61.6-1.6-1.61.61.6-1.61.6-1.61.51.01.11.11.61.6
Delay disc. indifference point, 24s delay0.80.92.10.7-0.71.01.1-1.0-1.2-1.10.9-1.5-0.9-1.1-0.9-0.90.90.9-0.9-1.01.0-0.90.9-0.9-0.50.10.1-1.1-0.8
Delay disc. indifference point, 4s delay0.10.10.60.2-0.2-0.4-0.30.40.20.2-0.30.80.60.20.20.2-0.2-0.30.30.3-0.30.2-0.20.4-0.7-0.5-0.50.40.5
Delay disc. indifference point, 8s delay0.20.20.4-0.10.1-0.6-0.40.70.30.2-0.30.40.50.20.60.6-0.6-0.60.60.6-0.60.5-0.50.5-0.00.10.10.40.5
Indifference point function ln k0.71.14.71.6-1.61.01.1-1.0-1.1-1.01.00.1-0.8-1.3-0.9-0.80.80.8-0.8-0.70.7-0.80.8-0.6-2.2-1.5-1.6-0.4-0.2
Indifference point function log k0.71.14.71.6-1.61.01.1-1.0-1.1-1.01.00.1-0.8-1.3-0.9-0.80.80.8-0.8-0.70.7-0.80.8-0.6-2.2-1.5-1.6-0.4-0.2
Patch foraging total patch changes 0 sec0.50.81.6-0.90.9-1.0-1.11.01.10.9-1.01.30.91.00.90.9-0.9-0.90.90.9-0.90.9-0.91.00.80.70.70.70.7
Patch foraging total patch changes 12 sec0.30.31.2-0.80.8-0.7-0.80.60.80.8-0.60.10.50.80.40.4-0.4-0.40.40.4-0.40.3-0.30.41.10.50.5-0.2-0.2
Patch foraging total patch changes 18 sec1.92.94.2-1.81.8-1.9-2.01.82.12.0-1.81.51.72.01.71.7-1.7-1.71.71.7-1.71.6-1.61.61.71.21.21.41.2
Patch foraging total patch changes 24 sec2.13.75.4-2.12.1-2.2-2.22.12.32.2-2.01.71.92.31.91.9-1.9-1.91.91.9-1.91.8-1.81.82.11.31.31.51.3
Patch foraging total patch changes 6 sec3.35.17.4-2.62.6-2.3-2.42.32.52.3-2.32.22.22.52.22.2-2.2-2.22.22.1-2.12.1-2.12.12.72.22.21.91.6
Patch foraging time to switch 0 sec1.53.04.11.8-1.81.71.8-1.7-1.8-1.81.8-1.3-1.7-1.8-1.8-1.81.81.7-1.7-1.71.7-1.81.8-1.7-1.5-1.7-1.6-2.0-1.7
Patch foraging water rate 0 sec1.73.74.5-2.12.1-1.9-2.01.92.12.1-2.01.51.92.11.91.9-1.9-1.91.91.9-1.81.9-1.91.81.91.81.82.11.6
Patch foraging water rate 12 sec0.10.10.60.5-0.50.30.3-0.3-0.3-0.30.40.4-0.3-0.6-0.3-0.30.30.3-0.3-0.30.3-0.30.3-0.3-0.8-0.4-0.4-0.10.1
Patch foraging water rate 18 sec0.50.81.81.2-1.20.91.0-0.9-1.0-0.91.0-0.4-0.8-1.1-0.8-0.80.80.8-0.8-0.70.7-0.70.7-0.9-1.4-1.0-1.0-0.2-0.1
Patch foraging water rate 24 sec0.10.20.3-0.50.5-0.4-0.50.40.50.6-0.50.00.50.50.40.4-0.4-0.40.40.4-0.30.4-0.40.50.40.50.50.40.3
Patch foraging water rate 6 sec1.21.72.6-1.11.1-1.3-1.31.31.31.4-1.31.31.41.11.31.4-1.4-1.41.41.4-1.41.4-1.41.40.51.01.01.51.6
Seeking ratio, delayed vs. immediate footshock1.72.02.8-1.61.6-1.4-1.41.41.41.4-1.51.11.51.51.41.4-1.4-1.31.31.3-1.31.4-1.41.41.71.61.61.41.2
Distance traveled before self-admin3.04.05.1-1.71.7-2.0-1.92.01.91.9-2.02.12.11.62.22.2-2.2-2.22.22.2-2.22.1-2.12.20.81.81.82.02.2
Distance traveled after self-admin0.00.10.2-0.00.0-0.1-0.10.10.00.0-0.10.20.2-0.10.30.3-0.3-0.30.30.3-0.30.3-0.30.2-0.20.50.50.30.4
Extensor digitorum longus weight0.83.35.91.6-1.62.02.0-1.9-2.1-2.11.9-2.4-2.0-1.8-1.8-1.81.81.8-1.8-1.91.9-1.81.8-1.8-1.0-0.8-0.8-2.0-1.7
Bone: elastic displacement2.83.23.6-1.81.8-1.8-1.91.81.81.8-1.91.51.81.81.91.9-1.9-1.91.91.8-1.81.8-1.81.91.41.61.61.71.7
Bone: elastic work8.611.313.6-3.53.5-3.5-3.63.53.63.5-3.63.03.53.43.33.3-3.3-3.33.33.3-3.33.3-3.33.72.83.23.22.93.0
Bone: endosteal estimation0.00.10.8-0.10.10.10.1-0.1-0.00.1-0.1-0.9-0.20.1-0.1-0.20.20.2-0.2-0.20.2-0.20.2-0.00.40.20.2-0.3-0.5
Bone: endosteal perimeter0.10.21.40.3-0.30.30.3-0.4-0.2-0.20.2-1.2-0.4-0.1-0.4-0.40.40.4-0.4-0.40.4-0.40.4-0.3-0.1-0.5-0.5-0.5-0.8
Epididymis fat weight8.629.635.15.9-5.95.75.7-5.7-5.7-5.55.7-4.3-5.5-5.7-5.5-5.45.45.4-5.4-5.35.3-5.45.4-5.5-5.5-5.4-5.4-4.9-4.6
Delta time in closed arm before/after self-admin2.62.54.2-1.01.0-1.6-1.31.71.21.4-1.42.01.71.01.71.8-1.8-1.81.81.8-1.81.8-1.81.70.11.01.01.82.1
Delta time in open arm before/after self-admin6.05.910.01.8-1.82.42.0-2.5-1.9-2.02.2-2.9-2.6-1.5-2.7-2.72.72.7-2.7-2.72.8-2.72.7-2.6-0.6-2.2-2.2-2.7-3.2
Diff in mean of infusions in LGA sessions0.60.72.10.9-0.90.70.6-0.7-0.5-0.70.8-0.6-0.8-0.4-0.9-0.90.90.9-0.9-0.80.8-0.90.9-0.9-0.6-1.4-1.4-0.9-1.1
Delay discount exponential model param0.40.40.80.3-0.30.80.6-0.8-0.5-0.40.6-0.7-0.8-0.4-0.7-0.80.80.8-0.8-0.80.8-0.80.8-0.80.0-0.5-0.5-0.7-0.9
Extinction: sum of active levers before priming0.60.71.10.7-0.70.90.6-0.9-0.6-0.80.8-0.9-0.9-0.5-0.9-0.90.90.9-0.9-0.90.9-1.01.0-0.9-0.5-0.8-0.8-0.9-1.1
Active lever presses in extinction session 60.10.10.50.4-0.40.20.3-0.2-0.3-0.30.30.1-0.2-0.4-0.1-0.10.10.1-0.1-0.10.1-0.10.1-0.1-0.7-0.1-0.1-0.20.0
Bone: final force0.30.51.5-0.90.9-0.6-0.70.60.70.5-0.80.40.60.70.60.6-0.6-0.50.50.5-0.50.6-0.60.90.81.21.20.20.4
Bone: final moment0.30.51.3-0.90.9-0.6-0.70.60.70.6-0.80.40.70.70.60.6-0.6-0.60.60.5-0.50.6-0.61.00.71.11.10.30.5
Food consumed during 24 hour testing period0.50.62.3-0.40.4-0.7-0.60.80.60.7-0.71.50.90.30.70.8-0.8-0.80.80.8-0.80.8-0.80.9-0.40.60.61.01.4
Glucose1.32.12.3-1.51.5-1.5-1.51.51.51.5-1.41.11.41.41.51.5-1.5-1.51.51.5-1.51.5-1.51.31.41.41.41.21.4
Heart weight1.32.03.71.4-1.41.51.4-1.5-1.4-1.41.3-1.9-1.4-1.4-1.4-1.41.41.4-1.4-1.41.4-1.41.4-1.2-1.3-1.1-1.1-1.4-1.4
Delay discount hyperbolic model param0.80.91.30.6-0.61.10.9-1.1-0.8-0.70.9-1.0-1.1-0.7-1.0-1.01.01.0-1.0-1.01.0-1.01.0-1.1-0.3-0.7-0.7-1.0-1.2
Intermittent access intake day 1-15 change0.00.10.8-0.40.4-0.00.00.0-0.00.0-0.0-0.20.0-0.10.0-0.00.00.0-0.0-0.10.10.1-0.1-0.00.70.90.90.10.2
Intermittent access intake escalation0.10.10.6-0.40.40.20.2-0.2-0.2-0.10.1-0.6-0.2-0.2-0.2-0.20.20.2-0.2-0.30.3-0.10.1-0.20.70.80.8-0.1-0.1
Intermittent access intake escalation 20.30.41.6-0.90.9-0.5-0.50.50.40.5-0.50.10.50.40.50.5-0.5-0.40.40.4-0.40.5-0.50.40.91.31.30.40.5
Intermitt. access day 1 inactive lever presses0.10.31.1-0.80.8-0.4-0.40.40.40.4-0.5-0.40.40.40.40.3-0.3-0.30.30.3-0.20.4-0.30.41.11.01.00.30.1
Intermitt. access day 15 inactive lever presses0.61.34.2-1.71.7-1.1-1.31.11.41.5-1.20.31.01.40.90.9-0.9-0.90.90.8-0.80.9-0.90.82.01.31.30.90.5
Intermitt. access escalation Index1.52.14.21.9-1.91.31.4-1.3-1.5-1.61.70.1-1.2-1.6-1.3-1.31.31.2-1.2-1.11.1-1.21.2-1.5-2.0-2.0-2.1-1.0-0.7
Intermittent access day 1 total infusions0.40.61.90.5-0.50.70.6-0.7-0.6-0.70.8-1.4-0.9-0.4-0.8-0.80.80.8-0.8-0.80.8-0.80.8-0.90.1-0.6-0.6-1.0-1.2
Intermittent access day 15 total infusions0.91.34.10.4-0.41.11.0-1.1-0.9-1.11.1-2.0-1.3-0.7-1.2-1.31.31.3-1.3-1.41.4-1.31.3-1.30.5-0.3-0.2-1.4-1.6
Intermittent access terminal intake (last 3 days)1.21.62.41.0-1.01.21.2-1.3-1.1-1.21.3-1.6-1.3-1.1-1.4-1.41.41.4-1.4-1.41.4-1.41.4-1.4-0.5-0.9-0.9-1.5-1.5
Intermittent access total infusions0.60.72.60.3-0.30.70.7-0.8-0.6-0.80.8-1.6-0.9-0.4-0.8-0.90.90.9-0.9-0.90.9-0.90.9-1.00.6-0.2-0.2-1.0-1.2
Intermittent access day 1 locomotion0.20.31.80.0-0.00.40.3-0.4-0.3-0.50.4-1.3-0.6-0.2-0.4-0.40.40.4-0.4-0.50.5-0.50.5-0.50.50.10.2-0.7-0.8
Intermittent access day 15 total locomotion0.40.84.30.2-0.20.90.9-0.9-0.9-1.00.8-2.1-1.0-0.7-0.8-0.80.80.8-0.8-0.91.0-0.80.8-0.90.50.50.5-0.9-1.0
Intermittent access total locomotion0.81.05.50.1-0.10.90.9-1.0-0.9-1.00.9-2.3-1.1-0.6-0.9-1.01.01.0-1.0-1.11.1-1.01.0-1.00.80.40.5-1.2-1.3
Intermittent access standard deviation0.10.21.9-0.70.7-0.0-0.1-0.00.20.1-0.1-0.8-0.10.3-0.1-0.20.20.2-0.2-0.30.3-0.10.2-0.31.40.90.9-0.2-0.3
Left kidney weight0.10.41.00.7-0.70.50.4-0.5-0.4-0.50.5-0.0-0.5-0.5-0.6-0.60.60.5-0.5-0.50.5-0.60.6-0.4-0.9-1.0-1.0-0.7-0.6
Right kidney weight0.21.01.81.1-1.10.90.9-0.9-0.9-0.90.9-0.6-1.0-0.8-1.0-0.90.90.9-0.9-0.90.9-1.01.0-0.8-1.1-1.3-1.3-0.9-1.0
Cocaine induced anxiety0.10.20.5-0.20.2-0.5-0.60.50.60.6-0.40.70.40.60.30.4-0.4-0.40.40.5-0.50.4-0.40.30.2-0.5-0.50.40.2
Post-drug Anxiety0.30.32.50.8-0.80.20.1-0.2-0.1-0.10.40.8-0.2-0.2-0.3-0.20.20.2-0.2-0.10.1-0.30.2-0.3-1.0-1.6-1.6-0.1-0.2
Baseline Anxiety0.10.10.50.5-0.50.30.4-0.3-0.4-0.30.30.3-0.2-0.4-0.3-0.30.30.3-0.3-0.20.2-0.20.2-0.3-0.7-0.5-0.5-0.10.0
Tail length0.41.42.91.4-1.41.21.2-1.2-1.2-1.01.20.1-1.0-1.3-1.2-1.21.21.2-1.2-1.11.1-1.11.1-1.1-1.7-1.5-1.5-1.0-0.6
Length with tail0.73.17.22.2-2.21.61.5-1.6-1.5-1.41.60.2-1.5-1.7-1.7-1.61.61.6-1.6-1.51.5-1.61.6-1.5-2.7-2.7-2.7-1.6-1.2
Length without tail0.62.04.41.7-1.71.31.2-1.3-1.2-1.11.4-0.2-1.3-1.4-1.4-1.31.31.3-1.3-1.21.2-1.31.3-1.3-1.9-2.1-2.1-1.4-1.2
Times rat made contact with spout0.20.20.90.1-0.1-0.2-0.20.20.10.3-0.30.80.4-0.00.40.4-0.4-0.40.40.4-0.40.4-0.40.6-0.80.20.20.60.9
Lifetime Intake0.91.13.30.6-0.61.00.9-1.0-0.8-0.91.0-1.8-1.2-0.6-1.1-1.11.11.1-1.1-1.21.2-1.21.2-1.10.2-0.6-0.6-1.3-1.5
Liver weight, left5.48.911.73.3-3.32.93.0-2.9-3.0-2.93.0-2.2-3.0-3.0-3.0-2.92.92.9-2.9-2.82.8-2.92.9-2.9-3.1-3.4-3.4-2.9-2.7
Liver weight, right4.47.712.13.2-3.22.72.7-2.7-2.7-2.72.7-2.0-2.7-2.6-2.7-2.72.72.7-2.6-2.62.5-2.72.7-2.6-3.0-3.5-3.5-2.7-2.6
Locomotor activity0.10.11.1-0.20.2-0.4-0.50.40.50.5-0.21.00.30.40.10.2-0.2-0.20.20.2-0.20.2-0.20.20.2-0.3-0.30.30.2
Locomotor testing distance0.10.10.5-0.30.3-0.5-0.50.40.60.6-0.30.70.40.50.30.3-0.3-0.30.30.3-0.30.3-0.30.20.4-0.1-0.10.50.3
Locomotor testing rearing0.20.30.7-0.60.6-0.7-0.70.70.80.8-0.50.80.60.60.50.5-0.5-0.50.50.5-0.50.5-0.50.30.60.20.20.50.5
Locomotion in novel chamber1.52.03.1-1.11.1-1.3-1.11.41.01.2-1.21.31.40.71.61.6-1.6-1.61.61.6-1.61.6-1.61.60.51.71.71.51.8
Locomotion in novel chamber post-restriction0.20.22.80.8-0.80.20.3-0.2-0.3-0.30.20.5-0.1-0.6-0.1-0.10.00.0-0.00.0-0.0-0.10.10.1-1.7-0.8-0.8-0.10.3
Fecal boli incidents, locomotor time 11.01.52.50.9-0.91.51.4-1.5-1.4-1.41.3-1.6-1.5-1.2-1.2-1.31.31.3-1.3-1.31.3-1.21.2-1.4-0.4-0.4-0.4-1.3-1.2
Change in fecal boli incidents, locomotor task0.00.00.2-0.10.1-0.2-0.10.20.10.0-0.2-0.40.30.10.00.00.00.0-0.0-0.00.0-0.00.00.20.10.20.2-0.0-0.1
Time >=10cm from walls, locomotor time 10.10.10.7-0.40.40.0-0.1-0.00.0-0.20.0-0.60.00.1-0.1-0.10.10.1-0.1-0.20.2-0.10.1-0.10.90.80.8-0.1-0.1
Bouts of movement, locomotor time 10.50.61.6-1.01.0-0.7-0.70.70.60.6-0.7-0.10.70.60.70.7-0.7-0.70.70.6-0.60.7-0.70.71.01.31.30.70.7
Total resting periods, locomotor time 10.30.31.5-0.90.9-0.5-0.40.50.40.4-0.5-0.30.40.40.40.4-0.4-0.40.40.3-0.30.4-0.40.41.11.21.20.40.4
Rest time, locomotor task time 10.10.21.1-0.60.60.20.0-0.20.00.1-0.2-0.8-0.00.3-0.1-0.20.20.2-0.2-0.30.3-0.10.2-0.01.00.80.9-0.2-0.4
Distance moved, locomotor task time 10.10.21.10.1-0.1-0.5-0.40.50.40.3-0.31.10.50.30.30.4-0.4-0.40.40.5-0.50.3-0.30.4-0.5-0.5-0.50.40.5
Vertical activity count, locomotor time 10.10.11.10.5-0.5-0.2-0.20.20.1-0.10.10.50.10.1-0.1-0.10.10.0-0.00.0-0.0-0.10.1-0.0-0.5-1.0-1.0-0.1-0.1
Time >=10cm from walls, locomotor time 20.71.02.4-0.10.10.90.7-0.9-0.6-1.00.6-1.5-0.8-0.1-1.1-1.21.21.2-1.2-1.31.4-1.11.1-0.91.30.60.6-1.1-1.4
Bouts of movement, locomotor time 20.40.61.1-0.60.6-0.8-0.80.80.80.9-1.01.10.90.80.70.7-0.7-0.70.70.7-0.70.7-0.70.90.20.40.30.90.8
Total resting periods, locomotor time 20.20.30.5-0.50.5-0.5-0.50.50.50.6-0.70.70.70.50.50.5-0.5-0.50.50.5-0.50.5-0.50.70.10.40.40.60.6
Rest time, locomotor task time 20.40.51.6-1.01.0-0.5-0.60.50.60.7-0.60.20.60.70.60.6-0.6-0.60.60.5-0.50.6-0.60.41.31.01.00.40.3
Distance moved, locomotor task time 20.10.10.80.5-0.5-0.1-0.10.10.0-0.00.10.70.1-0.20.00.1-0.1-0.10.10.1-0.20.0-0.00.1-0.8-0.9-0.90.10.2
Vertical activity count, locomotor time 20.20.32.00.7-0.7-0.0-0.00.00.0-0.10.20.60.1-0.1-0.2-0.20.20.1-0.1-0.00.0-0.20.2-0.0-1.0-1.4-1.4-0.1-0.1
Light reinforcement 10.00.00.40.3-0.3-0.1-0.00.10.0-0.00.10.50.00.0-0.0-0.00.0-0.00.00.1-0.1-0.00.0-0.1-0.2-0.6-0.60.1-0.0
Light reinforcement 20.20.40.7-0.20.2-0.7-0.70.70.70.7-0.60.80.70.70.60.6-0.7-0.70.70.7-0.70.6-0.60.7-0.2-0.3-0.30.70.5
Bone: marrow area0.00.10.8-0.20.20.10.0-0.1-0.00.1-0.1-0.9-0.10.2-0.1-0.10.10.1-0.1-0.20.2-0.10.10.00.40.30.3-0.2-0.4
Bone: maximum diameter0.20.51.4-0.90.9-0.5-0.60.50.60.6-0.7-0.50.50.70.60.6-0.6-0.60.60.5-0.50.6-0.60.71.01.21.20.30.3
Bone: maximum force0.50.93.0-1.31.3-0.8-0.90.80.80.8-1.00.40.80.90.80.8-0.8-0.80.80.7-0.70.8-0.81.11.21.71.70.50.7
Bone: maximum moment0.61.02.7-1.21.2-0.8-0.90.90.90.8-1.10.40.90.90.90.9-0.9-0.80.80.8-0.80.9-0.91.11.11.71.70.70.8
Mean time between licks in bursts0.51.24.10.9-0.91.21.3-1.2-1.3-1.21.1-2.0-1.2-1.2-1.0-1.01.01.0-1.0-1.11.1-1.01.0-1.0-0.7-0.5-0.4-1.1-1.0
Mean num. licks in bursts0.50.74.01.4-1.40.91.0-0.8-1.1-0.90.9-0.0-0.7-1.3-0.6-0.60.60.6-0.6-0.50.5-0.60.6-0.4-2.0-0.9-0.9-0.40.1
Cd content in liver0.60.61.6-0.90.9-1.0-1.00.91.11.1-0.90.60.81.20.70.7-0.7-0.70.70.7-0.70.7-0.70.61.30.30.30.50.1
Co content in liver0.60.73.0-1.11.1-0.8-0.90.80.90.8-0.70.00.71.10.70.7-0.7-0.70.70.7-0.60.7-0.70.51.70.90.91.00.5
Cu content in liver2.02.42.7-1.71.7-1.6-1.61.51.61.7-1.61.21.51.61.61.5-1.5-1.51.51.5-1.51.5-1.51.51.61.51.51.51.2
Fe content in liver2.12.64.91.4-1.41.41.3-1.5-1.2-1.41.4-1.3-1.6-1.0-1.8-1.71.71.7-1.7-1.71.7-1.81.8-1.7-0.7-1.8-1.8-1.9-2.2
K content in liver0.20.20.20.4-0.40.50.4-0.5-0.4-0.40.4-0.2-0.4-0.4-0.4-0.40.40.4-0.4-0.40.4-0.40.4-0.4-0.5-0.4-0.4-0.4-0.3
Mg content in liver0.80.91.8-1.11.1-1.0-1.20.91.21.1-1.20.70.91.30.80.8-0.8-0.80.80.8-0.80.8-0.81.01.10.60.60.50.4
Mn content in liver0.30.30.5-0.70.7-0.5-0.60.50.60.6-0.50.50.50.60.60.6-0.6-0.60.60.6-0.60.6-0.60.50.70.70.70.70.5
Na content in liver0.40.41.20.8-0.80.60.5-0.6-0.4-0.30.6-0.3-0.6-0.4-0.6-0.60.60.6-0.6-0.60.5-0.70.7-0.7-0.8-1.1-1.1-0.7-0.7
Rb content in liver0.10.10.4-0.20.20.1-0.0-0.10.1-0.10.10.2-0.10.1-0.3-0.30.30.3-0.3-0.30.4-0.30.3-0.30.70.00.1-0.5-0.5
Se content in liver1.21.44.7-1.71.7-1.3-1.51.21.61.3-1.40.11.01.80.90.9-0.9-0.90.90.8-0.80.8-0.81.02.21.11.10.80.1
Sr content in liver0.30.20.50.5-0.50.60.6-0.5-0.6-0.50.6-0.1-0.4-0.7-0.5-0.50.50.5-0.5-0.40.4-0.30.3-0.6-0.6-0.2-0.20.20.3
Zn content in liver0.30.41.10.3-0.30.40.2-0.4-0.2-0.30.3-0.5-0.5-0.0-0.7-0.70.70.7-0.7-0.70.7-0.80.8-0.5-0.1-0.7-0.7-0.8-1.1
Bone: minimum diameter0.00.10.3-0.20.2-0.2-0.20.20.20.2-0.3-0.60.10.40.20.2-0.2-0.20.20.2-0.20.2-0.20.30.30.10.1-0.0-0.1
Time in familiar zone, hab. session 10.20.20.9-0.20.2-0.4-0.40.40.40.4-0.40.60.50.30.50.5-0.5-0.50.50.5-0.50.5-0.50.4-0.00.10.10.90.8
Time in novel zone, hab. session 10.10.10.40.1-0.10.20.2-0.2-0.2-0.20.2-0.2-0.2-0.2-0.3-0.30.30.3-0.3-0.30.3-0.30.3-0.30.0-0.1-0.1-0.6-0.4
Total zone transitions, hab. session 10.00.00.1-0.10.10.00.0-0.0-0.00.1-0.0-0.3-0.10.10.00.0-0.0-0.00.00.0-0.00.0-0.0-0.00.10.00.0-0.0-0.1
Total locomotion distance, hab. session 10.10.10.3-0.10.1-0.3-0.30.30.30.3-0.30.50.30.20.40.4-0.4-0.40.40.4-0.40.4-0.40.3-0.10.00.00.40.5
Locomotion velocity, hab. session 10.20.40.4-0.60.6-0.6-0.60.60.60.7-0.60.60.50.60.60.6-0.6-0.60.60.7-0.70.7-0.70.60.40.50.50.60.5
Time in familiar zone, hab. session 20.30.31.4-0.40.4-0.7-0.70.60.70.7-0.61.20.60.70.50.5-0.5-0.60.60.6-0.60.5-0.50.50.3-0.2-0.20.50.4
Time in novel zone, hab. session 20.10.10.3-0.30.3-0.1-0.10.20.10.1-0.2-0.20.10.10.20.2-0.2-0.20.20.1-0.10.2-0.20.30.20.60.60.00.2
Total zone transitions, hab. session 20.40.51.70.6-0.60.90.9-0.9-0.8-0.70.7-1.3-0.9-0.6-0.6-0.60.60.6-0.6-0.60.6-0.60.6-0.8-0.3-0.5-0.5-0.5-0.7
Total locomotion distance, hab. session 20.10.20.6-0.50.5-0.2-0.20.20.30.4-0.4-0.40.10.50.40.4-0.4-0.40.40.4-0.40.4-0.40.20.80.40.40.40.1
Locomotion velocity, hab. session 20.10.20.6-0.50.5-0.2-0.20.20.30.5-0.4-0.40.10.60.40.4-0.4-0.40.40.4-0.40.4-0.40.30.80.40.40.50.1
Novel to familiar place preference ratio0.80.91.10.9-0.91.01.0-1.0-1.0-1.01.0-1.0-1.0-1.0-1.0-1.01.01.0-1.0-1.01.0-1.01.0-1.0-0.7-0.6-0.6-0.8-0.8
Novelty place preference1.11.21.41.1-1.11.11.1-1.1-1.2-1.21.2-1.0-1.1-1.2-1.1-1.11.11.1-1.1-1.21.2-1.11.1-1.1-1.0-0.8-0.8-1.0-0.9
Time in novel zone, NPP test1.21.21.51.1-1.11.11.2-1.1-1.2-1.21.2-1.0-1.1-1.2-1.2-1.21.21.2-1.2-1.21.2-1.21.2-1.1-1.0-0.9-0.9-1.1-1.0
Total zone transitions, NPP test0.10.11.1-0.10.10.20.1-0.2-0.00.00.1-1.1-0.30.1-0.2-0.20.20.2-0.2-0.20.2-0.20.2-0.20.4-0.0-0.0-0.4-0.6
Total locomotion distance, NPP test0.91.32.6-1.41.4-1.1-1.21.01.21.4-1.20.30.91.41.11.1-1.1-1.11.11.1-1.11.1-1.11.01.61.11.10.90.6
Locomotion velocity, NPP test1.11.62.9-1.51.5-1.2-1.21.11.31.4-1.30.31.01.51.31.2-1.2-1.21.21.2-1.21.2-1.21.11.71.21.21.10.8
Intraocular pressure1.42.04.6-1.71.7-1.2-1.11.21.11.1-1.30.81.31.11.41.4-1.4-1.31.31.3-1.31.4-1.41.21.72.12.11.41.4
Delta distance traveled before/after self-admin2.82.93.81.5-1.51.81.7-1.8-1.7-1.71.8-2.0-1.9-1.6-1.8-1.81.81.8-1.8-1.81.8-1.81.8-1.8-1.0-1.3-1.3-1.8-1.8
Delta ambulatory time before/after self-admin1.92.43.81.2-1.21.51.3-1.6-1.2-1.31.5-1.8-1.7-1.0-1.7-1.71.71.7-1.7-1.71.7-1.71.7-1.8-0.4-1.5-1.5-1.6-2.0
Parametrial fat weight6.214.617.94.2-4.23.93.9-3.9-3.9-3.84.0-2.8-3.8-3.8-3.8-3.83.83.7-3.7-3.73.6-3.83.8-3.9-3.8-4.2-4.2-3.7-3.5
Pavlov. Cond. lever latency0.00.00.1-0.20.20.0-0.0-0.00.00.1-0.00.30.0-0.10.0-0.00.00.0-0.0-0.00.00.0-0.0-0.10.20.30.30.20.2
Pavlov. Cond. magazine entry latency0.10.10.70.4-0.40.20.2-0.3-0.1-0.20.2-0.2-0.3-0.1-0.3-0.30.30.2-0.2-0.20.2-0.30.3-0.2-0.4-0.8-0.8-0.5-0.6
Pavlov. Cond. change in total contacts0.20.20.4-0.30.3-0.4-0.40.40.50.4-0.5-0.00.40.70.50.5-0.5-0.60.60.6-0.60.5-0.50.50.3-0.1-0.10.70.3
Pavlov. Cond. index score0.00.00.30.2-0.20.10.0-0.1-0.0-0.10.0-0.4-0.10.2-0.00.0-0.0-0.00.00.0-0.1-0.00.00.0-0.2-0.6-0.6-0.1-0.3
Pavlov. Cond. latency score0.10.10.40.4-0.40.20.1-0.2-0.1-0.20.1-0.4-0.20.0-0.1-0.10.10.1-0.1-0.10.1-0.20.2-0.1-0.3-0.6-0.6-0.3-0.4
Pavlov. Cond. lever contacts0.10.10.20.3-0.30.20.2-0.2-0.2-0.30.2-0.4-0.2-0.0-0.1-0.10.10.1-0.1-0.10.1-0.20.2-0.1-0.2-0.5-0.5-0.2-0.3
Pavlov. Cond. magazine entry number0.10.10.20.0-0.00.30.3-0.2-0.3-0.30.3-0.2-0.2-0.4-0.3-0.30.30.3-0.3-0.30.4-0.20.2-0.30.10.50.5-0.10.0
Pavlov. Cond. intertrial magazine entries0.40.40.8-0.90.9-0.6-0.60.60.70.7-0.7-0.10.50.70.60.6-0.6-0.60.60.6-0.50.6-0.60.60.90.90.90.70.4
Pavlov. Cond. lever-magazine prob. diff.0.00.00.20.1-0.1-0.1-0.10.00.10.1-0.1-0.40.00.30.10.1-0.1-0.10.10.1-0.20.1-0.10.1-0.0-0.5-0.5-0.0-0.3
Pavlov. Cond. response bias0.10.10.50.3-0.30.10.1-0.1-0.1-0.10.1-0.3-0.10.1-0.1-0.10.10.1-0.1-0.10.0-0.10.1-0.0-0.3-0.7-0.7-0.2-0.4
Pavlov. Cond. lever latency2.73.65.02.0-2.02.12.2-2.1-2.2-2.22.0-1.8-1.9-2.2-1.9-1.91.91.9-1.9-1.91.9-1.91.9-1.8-1.8-1.2-1.2-1.8-1.5
Pavlov. Cond. magazine entry latency0.20.20.4-0.30.3-0.6-0.60.60.60.6-0.50.60.50.60.50.5-0.5-0.50.50.5-0.50.4-0.40.50.1-0.1-0.10.40.4
Pavlov. Cond. change in total contacts1.42.33.3-1.61.6-1.7-1.81.61.81.8-1.61.41.51.81.51.5-1.5-1.51.51.5-1.51.4-1.41.51.51.11.11.21.2
Pavlov. Cond. index score2.43.24.5-1.81.8-2.0-2.11.92.12.1-1.91.71.82.11.81.8-1.8-1.81.81.8-1.81.7-1.71.71.71.11.11.61.4
Pavlov. Cond. latency score2.83.85.2-2.02.0-2.2-2.32.12.32.3-2.11.72.02.21.91.9-1.9-1.91.92.0-2.01.9-1.91.91.81.31.21.81.6
Pavlov. Cond. lever contacts1.62.23.3-1.51.5-1.7-1.81.61.81.8-1.61.51.51.81.51.5-1.5-1.51.51.5-1.51.4-1.41.41.40.90.91.41.1
Pavlov. Cond. magazine entry number0.00.10.20.3-0.30.30.4-0.2-0.4-0.40.3-0.2-0.1-0.4-0.1-0.10.10.1-0.1-0.10.1-0.10.1-0.1-0.4-0.0-0.0-0.0-0.0
Pavlov. Cond. intertrial magazine entries0.40.61.00.7-0.70.91.0-0.9-1.0-0.90.8-1.0-0.8-0.9-0.7-0.80.80.8-0.8-0.80.8-0.70.7-0.8-0.6-0.4-0.3-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.1.82.43.5-1.61.6-1.7-1.81.71.91.9-1.71.51.51.81.51.5-1.5-1.51.51.6-1.61.5-1.51.51.50.90.91.41.2
Pavlov. Cond. response bias1.21.62.5-1.21.2-1.5-1.61.41.61.6-1.31.51.31.51.31.3-1.3-1.31.31.3-1.31.2-1.21.21.00.40.41.00.9
Time in closed arm before self-admin1.82.32.81.4-1.41.51.4-1.6-1.4-1.51.5-1.2-1.6-1.3-1.6-1.61.61.6-1.6-1.61.6-1.61.6-1.6-1.0-1.5-1.5-1.6-1.7
Time in closed arm after self-admin0.20.31.00.1-0.1-0.30.10.3-0.20.1-0.11.00.5-0.40.50.5-0.5-0.50.50.6-0.60.6-0.60.4-0.80.40.40.51.0
Time in open arm before self-admin2.83.14.3-1.81.8-1.7-1.51.71.51.6-1.71.51.81.41.81.8-1.8-1.81.81.8-1.81.9-1.91.81.42.12.11.92.0
Time in open arm after self-admin0.60.72.20.2-0.20.80.5-0.9-0.5-0.50.6-1.5-0.9-0.2-0.9-1.01.01.0-1.0-1.01.1-1.01.0-0.90.6-0.2-0.2-0.9-1.3
Bone: periosteal estimation0.30.61.5-1.11.1-0.7-0.80.70.80.8-0.9-0.20.60.90.70.7-0.7-0.70.70.6-0.60.7-0.70.91.11.21.20.40.3
Bone: periosteal perimeter0.10.10.3-0.50.5-0.3-0.40.30.40.4-0.5-0.40.30.50.40.4-0.4-0.40.40.3-0.30.3-0.30.50.40.50.50.30.1
Bone: post-yield work0.50.71.10.8-0.81.01.0-1.0-1.1-1.10.9-1.0-0.9-1.0-0.7-0.70.70.7-0.7-0.80.8-0.70.7-0.8-0.8-0.3-0.3-0.5-0.6
Progressive ratio test 1 active lever presses0.30.40.9-0.70.7-0.6-0.80.60.80.6-0.60.40.60.90.50.5-0.5-0.50.50.5-0.60.5-0.50.41.00.30.30.60.3
Progressive ratio test 1 breakpoint0.40.41.1-0.80.8-0.7-0.90.70.90.7-0.70.40.61.00.60.6-0.6-0.60.60.6-0.60.6-0.60.51.00.30.30.60.3
Progressive ratio test 1 inactive lever presses1.11.63.5-1.61.6-1.2-1.31.21.31.2-1.30.51.21.41.21.1-1.1-1.11.11.1-1.01.1-1.11.11.91.61.61.20.9
Progressive ratio test 2 active lever presses0.40.51.7-0.90.9-0.6-0.70.60.70.6-0.6-0.20.50.80.60.6-0.6-0.60.60.5-0.50.6-0.50.61.31.01.00.50.2
Progressive ratio test 2 breakpoint0.40.51.8-1.01.0-0.6-0.70.60.70.6-0.6-0.20.50.80.60.6-0.6-0.50.50.5-0.50.5-0.50.51.31.01.00.40.2
Progressive ratio test 2 inactive lever presses0.10.21.1-0.70.7-0.3-0.30.30.30.4-0.4-0.30.30.30.30.3-0.3-0.30.30.2-0.20.3-0.30.40.81.01.10.30.2
Incentive Sensitization - Responses0.10.10.9-0.30.30.00.1-0.0-0.1-0.0-0.0-1.0-0.20.00.0-0.00.00.0-0.0-0.10.1-0.10.10.10.50.50.5-0.3-0.4
Incentive Sensitization - Breakpoint0.10.11.0-0.20.20.10.1-0.1-0.1-0.10.0-1.0-0.20.0-0.0-0.00.00.0-0.0-0.10.1-0.10.10.00.50.40.4-0.3-0.4
Sum of active levers in priming session hrs 5-61.21.11.81.0-1.01.00.8-1.0-0.8-0.91.0-1.0-1.1-0.6-1.1-1.11.11.1-1.1-1.11.1-1.21.2-1.1-0.6-1.3-1.3-1.2-1.3
Progressive ratio0.10.21.3-0.70.7-0.2-0.30.20.30.2-0.4-0.50.30.50.20.2-0.2-0.20.20.1-0.10.2-0.20.31.01.11.10.20.1
Food seeking constrained by brief footshock0.10.10.3-0.00.00.20.1-0.2-0.1-0.10.2-0.6-0.3-0.1-0.3-0.30.30.3-0.3-0.30.3-0.30.3-0.40.2-0.0-0.0-0.3-0.4
Seeking ratio, punishment vs. effort0.10.10.70.5-0.50.10.2-0.1-0.2-0.20.30.4-0.2-0.4-0.1-0.10.10.1-0.1-0.00.0-0.10.1-0.3-0.8-0.7-0.7-0.10.0
Retroperitoneal fat weight0.83.47.82.3-2.31.71.7-1.7-1.6-1.51.8-0.5-1.7-1.8-1.7-1.71.71.6-1.6-1.51.5-1.71.7-1.8-2.5-2.8-2.8-1.5-1.5
Reaction time number correct0.61.13.00.5-0.51.31.2-1.3-1.2-1.01.0-1.7-1.2-1.1-1.1-1.11.11.2-1.2-1.21.3-1.11.1-1.1-0.10.20.3-0.9-1.0
Reaction time mean minus median0.10.30.70.6-0.60.50.5-0.5-0.4-0.40.5-0.2-0.6-0.4-0.5-0.50.50.5-0.5-0.50.4-0.50.5-0.6-0.5-0.8-0.8-0.6-0.5
Reaction time mean minus median AUC1.02.63.11.6-1.61.61.6-1.7-1.6-1.51.6-1.4-1.7-1.5-1.6-1.61.61.6-1.6-1.61.6-1.61.6-1.8-1.3-1.7-1.7-1.7-1.6
Reaction time num false alarms5.88.19.9-2.72.7-2.9-3.02.93.02.9-2.93.13.02.82.92.9-2.9-2.92.93.0-3.02.9-2.92.92.02.32.33.12.9
Reaction time num false alarms AUC5.48.49.8-2.82.8-2.9-3.03.03.02.9-2.93.03.02.83.03.0-3.0-3.03.03.0-3.03.0-3.03.02.12.52.53.13.0
Reaction time trials correct on left0.61.13.00.5-0.51.31.2-1.3-1.2-1.01.0-1.7-1.2-1.1-1.1-1.11.11.2-1.2-1.21.3-1.11.1-1.1-0.10.20.3-0.9-1.0
Reaction time trials on left0.61.23.10.6-0.51.31.2-1.3-1.2-1.11.1-1.7-1.2-1.2-1.1-1.11.21.2-1.2-1.31.3-1.11.1-1.1-0.10.30.3-0.9-0.9
Reaction time mean0.60.91.81.0-1.00.90.8-0.9-0.8-0.70.9-0.4-0.9-0.9-1.0-1.01.01.0-1.0-0.90.9-1.01.0-1.0-1.1-1.3-1.3-1.1-1.1
Reaction time mean AUC0.50.81.40.9-0.90.80.8-0.8-0.7-0.60.8-0.4-0.9-0.8-0.9-0.90.90.9-0.9-0.80.8-0.90.9-0.9-1.0-1.2-1.2-1.0-1.0
Median of all reaction times0.40.61.50.8-0.80.60.6-0.7-0.5-0.40.6-0.3-0.7-0.6-0.8-0.80.80.8-0.8-0.80.7-0.90.8-0.8-0.8-1.2-1.2-0.9-1.0
Reaction time omissions1.52.13.01.7-1.71.51.6-1.5-1.7-1.71.6-0.7-1.5-1.7-1.4-1.41.41.4-1.4-1.41.4-1.41.4-1.5-1.7-1.3-1.3-1.2-1.0
Reaction time false alarm rate6.08.210.8-2.62.6-3.0-3.13.03.02.9-2.93.33.02.93.03.0-3.0-3.03.03.0-3.13.0-3.03.01.92.02.03.02.9
Reaction time premature initiation rate0.50.72.31.1-1.10.60.6-0.6-0.6-0.70.70.5-0.6-0.7-0.7-0.70.70.7-0.6-0.60.6-0.70.7-0.6-1.3-1.5-1.5-0.7-0.6
Reaction time premature initiations0.50.81.21.1-1.10.90.9-0.9-0.9-0.90.9-0.1-0.8-0.9-0.9-0.90.90.9-0.9-0.90.9-0.90.9-0.8-1.1-1.0-1.0-0.8-0.7
Std. dev. reaction times0.61.11.41.0-1.01.11.1-1.1-1.0-1.01.1-0.7-1.1-1.1-1.1-1.11.11.1-1.1-1.11.1-1.11.1-1.2-0.9-0.9-0.9-1.2-1.0
Reaction time trials completed0.61.23.10.6-0.51.31.2-1.3-1.2-1.11.1-1.7-1.2-1.2-1.1-1.11.21.2-1.2-1.31.3-1.11.1-1.1-0.10.30.3-0.9-0.9
Reaction time trials AUC0.50.92.70.4-0.41.21.1-1.2-1.1-0.90.9-1.6-1.0-1.0-0.9-1.01.01.0-1.0-1.11.1-0.90.9-1.00.00.40.4-0.7-0.8
Run reversals in cocaine runway, females0.20.21.20.6-0.60.60.6-0.5-0.6-0.40.6-0.2-0.5-0.9-0.2-0.20.20.2-0.2-0.20.2-0.20.2-0.4-1.1-0.3-0.3-0.20.1
Run reversals in cocaine runway, males0.30.31.10.7-0.70.60.6-0.5-0.7-0.60.5-0.1-0.4-0.8-0.4-0.40.40.4-0.4-0.40.4-0.40.4-0.4-1.0-0.3-0.3-0.3-0.1
Latency to leave start box in cocaine runway1.21.32.2-0.90.9-1.2-1.11.21.11.2-1.21.51.31.11.21.2-1.2-1.21.21.3-1.31.2-1.21.30.50.80.81.21.3
Latency to leave start box in cocaine runway, F0.30.40.9-0.40.4-0.6-0.60.60.60.6-0.51.00.60.50.60.7-0.7-0.70.70.7-0.70.7-0.70.50.20.30.30.70.8
Latency to leave start box in cocaine runway, M0.60.51.0-0.40.4-0.7-0.50.80.40.7-0.80.90.90.50.80.8-0.8-0.80.80.8-0.80.8-0.81.00.00.60.60.81.0
Std. dev. time between licks in bursts0.10.21.2-0.00.00.50.6-0.5-0.6-0.40.3-1.1-0.3-0.6-0.2-0.20.20.3-0.3-0.30.4-0.20.2-0.20.00.90.9-0.1-0.1
Total sessions with >9 infusions1.01.21.71.0-1.01.11.0-1.1-1.0-1.01.0-1.3-1.1-0.9-1.1-1.11.11.1-1.1-1.11.1-1.11.1-1.0-0.8-1.0-1.0-1.3-1.3
Short access day 1 total inactive lever presses4.15.38.41.9-1.92.52.5-2.5-2.5-2.52.3-2.9-2.5-2.3-2.4-2.42.42.4-2.4-2.52.5-2.42.4-2.3-1.2-1.3-1.3-2.4-2.4
Short access day 10 total inactive lever presses0.10.21.5-0.80.8-0.0-0.1-0.00.10.2-0.3-0.90.00.20.0-0.00.00.1-0.1-0.20.2-0.00.00.11.11.21.2-0.1-0.2
Short access day 1 total infusions1.01.44.20.5-0.51.10.9-1.1-0.8-0.80.9-2.1-1.2-0.5-1.3-1.31.31.3-1.3-1.41.4-1.31.4-1.10.3-0.5-0.5-1.5-1.7
Short access day 10 total infusions0.70.91.40.9-0.90.90.8-0.9-0.8-0.80.9-0.9-1.0-0.7-1.0-1.01.01.0-1.0-1.01.0-1.01.0-0.9-0.7-1.1-1.1-1.1-1.2
Short access total infusions0.50.61.90.4-0.40.70.6-0.8-0.6-0.60.6-1.4-0.9-0.4-0.9-0.90.90.9-0.9-0.90.9-0.90.9-0.80.1-0.6-0.6-1.0-1.2
Short access day 1 locomotion0.10.10.5-0.30.30.1-0.1-0.10.10.00.0-0.6-0.10.3-0.2-0.20.20.2-0.2-0.30.3-0.20.2-0.20.70.10.1-0.3-0.5
Short access day 10 total locomotion0.61.14.7-1.61.6-0.9-1.20.91.21.1-1.10.00.81.40.80.7-0.7-0.70.70.7-0.60.8-0.80.82.21.41.40.70.4
Short access total locomotion0.40.42.3-1.01.0-0.5-0.60.50.60.5-0.6-0.50.40.80.40.4-0.4-0.40.40.3-0.30.4-0.40.41.51.11.10.30.1
One hour access (0.3 mA shock)0.10.11.0-0.50.5-0.2-0.20.10.30.1-0.1-0.6-0.00.40.10.1-0.1-0.10.10.1-0.10.1-0.1-0.01.00.30.3-0.1-0.3
Compulsive drug intake1.01.21.51.1-1.11.11.1-1.1-1.0-1.11.1-1.0-1.1-1.0-1.1-1.11.11.1-1.1-1.11.1-1.21.2-1.1-0.8-1.2-1.2-1.2-1.2
One hour access (shock baseline)0.10.20.7-0.60.6-0.4-0.40.40.50.3-0.3-0.10.30.50.40.4-0.4-0.40.40.3-0.30.4-0.40.20.80.50.50.30.2
Social response proportion2.83.23.71.9-1.91.91.9-1.9-1.9-1.91.8-1.2-1.8-1.8-1.8-1.81.81.8-1.8-1.81.8-1.81.8-1.7-1.6-1.7-1.7-1.7-1.7
Social responses1.72.22.91.2-1.21.61.6-1.6-1.6-1.51.5-1.2-1.6-1.5-1.6-1.61.61.7-1.7-1.71.7-1.61.6-1.5-0.8-0.8-0.8-1.6-1.5
Social time1.92.53.31.5-1.51.71.8-1.7-1.8-1.81.7-1.1-1.7-1.6-1.6-1.71.71.7-1.7-1.71.7-1.61.6-1.7-0.9-1.2-1.1-1.7-1.5
Soleus weight2.67.79.83.1-3.12.72.7-2.7-2.7-2.82.8-2.2-2.8-2.6-2.7-2.72.72.7-2.7-2.62.6-2.82.8-2.6-2.7-3.1-3.1-3.0-2.7
Bone: stiffness1.72.83.61.4-1.41.81.8-1.8-1.8-1.81.7-1.5-1.7-1.7-1.8-1.81.81.8-1.8-1.91.9-1.81.8-1.7-1.0-0.8-0.8-1.9-1.6
Tibialis anterior weight2.89.411.93.0-3.03.33.3-3.2-3.3-3.33.1-3.4-3.2-3.0-3.1-3.13.13.1-3.1-3.13.2-3.13.1-3.0-2.4-2.3-2.3-3.1-2.9
Time to tail flick, vehicle, before self-admin0.40.41.40.9-0.90.60.7-0.6-0.8-0.80.7-0.0-0.6-0.8-0.5-0.50.50.5-0.5-0.50.5-0.50.5-0.5-1.2-0.8-0.8-0.5-0.3
Time to tail flick, vehicle, after self-admin0.20.30.7-0.40.4-0.7-0.80.60.80.8-0.60.80.60.80.50.5-0.5-0.50.50.6-0.60.5-0.50.50.3-0.2-0.20.50.3
Time to tail flick, test, before self-admin0.00.00.20.1-0.10.10.3-0.1-0.3-0.20.10.10.0-0.40.00.0-0.0-0.00.0-0.00.00.1-0.1-0.1-0.10.50.50.10.3
Time to tail flick, test, after self-admin1.21.22.6-0.80.8-1.1-0.91.10.81.0-1.01.61.20.71.21.2-1.2-1.21.21.2-1.21.3-1.31.10.40.90.91.41.5
Delta time to tail flick, vehicle, before/after SA1.00.91.8-1.21.2-1.1-1.21.01.21.2-1.10.61.01.30.90.9-0.9-0.90.90.9-0.90.8-0.80.81.30.70.70.80.5
Delta time to tail flick, test, before/after SA0.80.81.2-1.01.0-0.9-1.00.91.11.1-1.00.80.91.10.80.8-0.8-0.80.80.8-0.80.8-0.80.81.00.60.60.80.7
Tibia length0.00.00.00.00.0-0.1-0.00.1-0.0-0.0-0.1-0.10.1-0.00.10.1-0.1-0.10.10.1-0.10.1-0.10.2-0.20.10.10.10.2
Ambulatory time before self-admin0.81.12.1-0.60.6-1.0-0.91.00.80.8-1.01.21.10.61.21.2-1.2-1.21.21.3-1.31.2-1.21.3-0.21.01.01.11.4
Ambulatory time after self-admin0.10.11.00.7-0.70.20.3-0.2-0.3-0.30.30.3-0.2-0.4-0.2-0.10.10.1-0.1-0.10.1-0.20.2-0.1-1.0-0.6-0.6-0.2-0.0
Bone: tissue strength1.21.22.0-0.80.8-1.2-1.21.21.11.0-1.21.41.21.01.21.2-1.2-1.21.21.2-1.21.2-1.21.40.20.60.61.11.2
Total heroin consumption1.92.22.71.6-1.61.51.4-1.5-1.4-1.61.5-1.1-1.5-1.4-1.5-1.51.51.5-1.5-1.41.4-1.51.5-1.5-1.4-1.6-1.6-1.5-1.5
Bone: trabecular number2.84.66.42.4-2.42.02.0-2.0-2.0-2.12.2-1.6-2.0-2.1-2.2-2.12.12.1-2.1-2.12.0-2.22.2-2.0-2.4-2.5-2.5-2.3-2.0
Bone: trabecular spacing0.30.41.6-0.80.8-0.4-0.30.40.30.3-0.5-0.00.50.40.60.5-0.5-0.50.50.5-0.40.6-0.60.50.91.31.30.80.7
Bone: trabecular thickness0.00.00.20.1-0.1-0.2-0.20.20.20.1-0.10.50.10.1-0.1-0.00.00.0-0.0-0.00.0-0.10.10.1-0.2-0.5-0.5-0.4-0.2
Bone: trabecular tissue density1.21.82.3-1.41.4-1.4-1.51.41.51.5-1.41.31.31.41.41.4-1.4-1.41.41.4-1.41.3-1.31.31.21.01.01.41.1
Water consumed over 24 hours0.10.11.00.1-0.1-0.3-0.40.30.40.4-0.31.00.40.30.20.2-0.2-0.20.20.3-0.30.2-0.20.4-0.5-0.4-0.40.30.3
Number of responses in last shaping day0.70.81.2-0.90.9-0.9-1.00.91.01.1-1.10.50.91.00.90.9-0.9-0.90.90.9-0.90.9-0.91.10.80.70.60.80.6