Hub : Genes

Nol11

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver isoform ratio XR_005490485.1 0.04 0.02 1.3e-04 0.03 0.02 0.01 0.02 4.4e-04 2.2e-03 7.6e-03 3.3e-03
2 Brain isoform ratio XR_005490485.1 0.27 0.17 2.9e-05 0.07 0.05 0.07 0.07 2.6e-07 2.9e-05 3.1e-07 9.1e-07
3 Liver isoform ratio NM_001402074.1 0.03 0.02 1.3e-03 0.01 0.01 0.01 0.01 9.4e-03 7.7e-03 5.4e-02 1.5e-02
4 Liver mRNA stability Nol11 0.05 0.02 1.4e-07 0.04 0.05 0.05 0.04 2.6e-05 7.1e-06 7.7e-06 4.6e-05
5 Brain isoform ratio NM_001402074.1 0.23 0.16 3.6e-05 0.07 0.05 0.07 0.06 3.2e-07 4.1e-05 2.1e-07 1.1e-06
6 PL isoform ratio NM_001402074.1 0.07 0.04 1.1e-07 0.05 0.07 0.06 0.07 2.0e-06 5.7e-08 1.6e-07 6.3e-08
7 PL isoform ratio XR_005490485.1 0.07 0.04 8.4e-08 0.09 0.07 0.07 0.07 1.4e-09 3.5e-08 5.7e-08 2.4e-08
8 NAcc mRNA stability Nol11 0.03 0.02 5.2e-03 0.01 0 0.01 0.01 1.1e-02 1.4e-01 4.9e-02 1.8e-02
9 Brain gene expression Nol11 0.1 0.05 2.0e-05 0.04 0.06 0.06 0.06 4.5e-05 1.5e-06 4.3e-06 4.8e-06
10 NAcc isoform ratio NM_001402074.1 0.06 0.03 1.2e-07 0.07 0.06 0.07 0.07 7.1e-09 2.5e-07 1.8e-08 4.3e-09
11 NAcc isoform ratio XR_005490485.1 0.06 0.03 1.8e-08 0.08 0.07 0.07 0.08 1.2e-09 3.1e-08 6.1e-09 1.5e-09
12 BLA mRNA stability Nol11 0.06 0.04 1.4e-03 0.06 0.04 0.04 0.04 5.0e-04 2.8e-03 3.4e-03 2.4e-03
13 Adipose isoform ratio NM_001402074.1 0.04 0.03 2.8e-05 0.03 0.02 0.02 0.02 1.2e-04 1.1e-03 5.1e-03 4.1e-03
14 Adipose isoform ratio XR_005490485.1 0.05 0.03 1.4e-05 0.04 0.03 0.02 0.02 4.4e-05 6.5e-04 5.7e-03 1.3e-03
15 PL mRNA stability Nol11 0.04 0.02 7.6e-05 0.03 0.04 0.03 0.03 7.3e-04 6.0e-05 4.7e-04 7.0e-04
16 BLA isoform ratio XR_005490485.1 0.16 0.1 7.2e-06 0.06 0.1 0.09 0.08 4.6e-04 8.7e-06 1.0e-05 4.6e-05
17 PL gene expression Nol11 0.03 0.02 3.6e-03 0.02 0.02 0.03 0.03 9.4e-04 1.3e-03 2.1e-04 4.0e-04
18 BLA isoform ratio NM_001402074.1 0.17 0.1 7.8e-06 0.06 0.09 0.09 0.08 3.6e-04 1.0e-05 1.2e-05 5.5e-05
19 Brain mRNA stability Nol11 0.04 0.03 1.5e-03 0.03 0.01 0.02 0.02 4.8e-04 1.7e-02 7.7e-03 4.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.50.91.5-0.6-0.7-1.1-1.11.0-1.2-1.01.0-0.2-1.0-1.11.21.2-1.2-1.00.4-0.5-0.40.7
Area under the delay curve0.40.43.20.6-0.30.30.31.1-0.30.0-0.0-1.00.30.3-0.00.1-0.1-0.2-0.50.50.61.8
BMI with tail0.72.18.80.2-0.30.01.0-0.20.60.6-0.8-2.51.61.6-0.8-1.11.1-0.7-1.83.01.82.7
BMI without tail0.91.98.8-1.2-1.8-1.2-0.10.9-0.6-0.50.4-3.00.70.80.3-0.10.1-1.5-1.82.31.72.2
Body weight0.83.28.7-2.5-2.9-2.6-1.62.0-1.7-1.71.6-2.3-1.0-0.91.71.1-1.1-2.0-1.11.20.91.7
Weight adjusted by age0.60.71.71.30.41.21.1-0.30.70.9-0.9-0.31.01.0-0.8-1.01.00.7-0.50.30.60.3
Bone surface3.66.310.3-3.0-2.2-3.2-3.22.1-2.8-2.92.90.2-3.1-3.12.92.9-2.9-1.91.1-1.9-1.3-0.4
Bone volume2.64.37.3-2.5-2.1-2.7-2.62.1-2.5-2.42.3-0.4-2.4-2.42.52.5-2.5-1.80.6-1.3-0.70.4
Breakpoint value in progressive ratio session0.20.21.20.1-0.9-0.00.10.40.40.2-0.20.0-0.3-0.3-0.2-0.80.80.8-0.40.10.3-1.1
Number of licking bursts0.00.00.3-0.20.10.10.0-0.20.20.2-0.10.10.00.0-0.1-0.20.20.3-0.1-0.10.1-0.6
Context. condit. distance diff. score0.00.00.10.00.10.10.1-0.20.30.3-0.2-0.30.10.1-0.20.1-0.10.3-0.30.10.3-0.3
Locomotion velocity, session 10.20.20.4-0.4-0.6-0.6-0.40.6-0.5-0.60.6-0.4-0.5-0.50.50.1-0.1-0.3-0.10.20.10.3
Locomotion distance, session 10.30.42.2-0.1-0.1-0.30.10.2-0.3-0.30.4-1.50.20.20.10.1-0.1-0.2-0.91.20.90.9
Locomotion velocity, session 20.40.43.9-0.9-0.5-0.6-0.4-0.30.3-0.10.10.1-0.6-0.6-0.0-0.50.50.8-0.4-0.10.3-2.0
Locomotion distance, session 20.40.61.50.00.00.20.5-0.50.70.4-0.4-1.10.40.4-0.7-1.01.00.9-1.21.21.2-0.9
Locomotion velocity, session 32.02.43.81.50.81.41.7-0.91.61.6-1.6-1.51.41.4-1.5-1.91.91.7-1.81.81.80.1
Locomotion distance, session 30.20.20.80.40.30.30.3-0.20.40.4-0.3-0.70.10.1-0.3-0.50.50.9-0.70.50.7-0.4
Stereotopy head waving bouts, day 30.60.72.41.50.71.11.1-0.20.60.8-0.8-0.30.90.9-0.7-1.01.00.3-0.40.60.41.0
Stereotopy head waving duration, day 30.81.02.21.50.61.31.2-0.00.71.0-1.0-0.71.11.1-0.9-1.21.20.7-0.80.90.91.0
Locomotion velocity, session 70.10.21.20.20.80.20.2-1.10.30.1-0.20.6-0.0-0.0-0.2-0.20.20.10.5-0.1-0.5-0.3
Locomotion distance, session 70.00.00.1-0.3-0.2-0.3-0.20.1-0.1-0.30.2-0.2-0.1-0.1-0.10.3-0.3-0.1-0.00.30.0-0.1
Stereotopy head waving bouts, day 71.71.93.51.50.91.51.6-0.91.61.6-1.6-0.51.31.3-1.5-1.91.91.7-1.11.01.1-0.7
Stereotopy head waving duration, day 73.03.76.52.11.62.32.1-1.62.32.3-2.30.11.71.7-2.1-2.52.52.5-1.00.71.1-1.4
Locomotion velocity, session 80.60.71.4-0.7-0.7-1.0-1.00.3-0.7-0.90.90.8-1.2-1.21.00.7-0.7-0.30.8-1.1-0.9-0.8
Locomotion distance, session 80.10.10.5-0.4-0.3-0.2-0.1-0.10.30.1-0.0-0.6-0.0-0.0-0.1-0.00.00.5-0.60.30.6-0.7
Degree of sensitization distance0.80.81.6-0.7-0.9-0.9-0.90.9-1.0-1.11.10.5-0.6-0.60.81.1-1.1-1.30.9-0.5-0.90.5
Degree of sensitization stereotypy2.93.26.01.21.21.71.8-1.62.32.1-2.1-0.61.61.6-2.1-2.32.32.5-1.61.31.5-1.7
Conditioned locomotion0.20.21.1-0.2-1.1-0.5-0.50.8-0.5-0.50.60.2-0.3-0.30.50.4-0.4-0.60.3-0.4-0.40.4
Cocaine response after cond. corrected0.20.20.80.70.90.70.4-0.50.20.1-0.10.60.40.4-0.2-0.50.50.10.5-0.2-0.40.3
Cocaine response after cond. not corrected0.70.71.80.71.31.10.7-1.30.90.7-0.80.90.60.6-0.8-0.90.91.10.2-0.4-0.1-1.0
Cocaine response before conditioning0.81.02.90.10.60.70.6-0.91.31.3-1.3-0.60.70.7-1.1-0.80.81.7-1.20.21.2-1.5
Saline control response0.30.43.3-0.6-1.8-0.6-0.11.00.20.1-0.1-0.60.10.1-0.1-0.30.3-0.0-0.70.50.6-0.2
Bone: connectivity density1.11.72.7-1.1-1.1-1.5-1.51.1-1.6-1.71.60.1-1.6-1.61.61.5-1.5-1.20.7-0.9-0.80.2
Bone: cortical apparent density2.83.76.12.12.32.22.4-1.81.72.0-2.1-1.52.32.2-1.9-1.51.50.8-1.42.51.52.0
Bone: cortical area0.91.46.7-1.7-1.0-1.4-0.70.7-0.6-0.40.4-2.6-0.3-0.30.60.9-0.9-0.6-1.81.41.61.2
Bone: cortical porosity1.71.97.1-2.7-2.1-1.9-1.81.0-0.7-0.90.90.2-1.7-1.71.00.7-0.70.1-0.2-1.4-0.0-2.3
Bone: cortical porosity0.80.94.4-2.1-1.4-1.2-1.10.6-0.2-0.20.2-0.9-0.8-0.80.30.3-0.30.4-1.2-0.21.0-1.4
Bone: cortical thickness6.410.621.12.32.92.83.6-2.93.13.5-3.5-3.73.83.8-3.2-2.82.81.9-3.74.63.72.2
Bone: cortical thickness3.84.48.11.02.41.62.1-2.92.42.3-2.3-2.12.42.4-2.3-1.41.41.6-2.32.82.30.2
Bone: cortical tissue density2.63.45.32.12.32.12.3-1.81.72.0-2.0-1.32.22.1-1.9-1.41.40.8-1.22.31.32.0
Condit. Reinf. active minus inactive responses1.01.15.0-2.2-1.9-1.2-1.11.6-0.5-0.30.4-1.3-0.5-0.60.30.7-0.70.1-1.2-0.21.2-1.0
Condit. Reinf. active-inactive response ratio0.40.41.5-1.2-1.2-0.6-0.81.1-0.2-0.20.1-0.4-0.5-0.50.10.5-0.50.3-0.5-0.60.5-1.2
Condit. Reinf. active responses1.41.76.7-2.6-2.3-1.6-1.52.0-0.9-0.70.7-1.3-0.8-0.80.61.2-1.2-0.4-1.1-0.31.0-0.7
Condit. Reinf. inactive responses0.80.92.5-1.6-1.2-1.3-1.11.2-1.1-0.90.9-0.9-0.6-0.60.91.2-1.2-1.0-0.40.10.30.7
Incentive salience index mean0.70.94.6-2.2-1.6-1.1-1.01.1-0.3-0.10.2-0.9-0.5-0.50.20.5-0.50.2-1.1-0.31.0-1.3
Condit. Reinf. lever presses0.30.41.6-0.8-0.5-0.00.1-0.10.80.8-0.7-0.20.40.4-0.6-0.40.40.8-0.90.10.8-1.3
Condit. Reinf. active minus inactive responses1.62.06.5-2.5-2.3-1.8-1.61.9-0.9-0.80.8-2.0-1.3-1.30.80.9-0.90.1-1.70.11.5-1.1
Condit. Reinf. active-inactive response ratio0.80.82.6-1.6-1.5-1.1-1.11.3-0.5-0.50.6-0.3-1.0-1.00.60.5-0.50.1-0.5-0.70.4-1.3
Condit. Reinf. active responses2.33.29.8-3.1-3.0-2.5-2.12.5-1.4-1.21.3-2.0-1.5-1.51.31.6-1.6-0.5-1.4-0.11.2-0.7
Condit. Reinf. inactive responses1.41.74.9-2.2-2.0-1.8-1.31.6-1.0-0.80.8-2.2-0.5-0.50.71.3-1.3-0.7-1.40.81.30.5
Condit. Reinf. lever presses0.91.25.0-2.2-1.6-1.3-0.80.60.00.0-0.1-1.8-0.2-0.2-0.10.6-0.60.3-1.80.61.7-1.1
Condit. Reinf. lever reinforcers received2.02.88.6-2.9-2.8-2.3-2.02.4-1.4-1.21.3-1.8-1.4-1.41.21.6-1.6-0.6-1.2-0.21.1-0.5
Conditioned reinforcement - actives0.10.10.9-0.4-0.9-0.10.00.50.00.10.1-0.50.20.20.0-0.40.40.1-0.60.10.5-0.2
Conditioned reinforcement - inactives1.01.13.1-1.8-1.2-1.5-1.20.9-1.3-1.41.2-0.8-1.0-1.01.21.0-1.0-1.0-0.2-0.00.10.5
Conditioned locomotion1.21.44.6-1.4-2.2-1.6-1.31.8-1.3-1.11.1-0.7-0.9-0.91.11.2-1.2-1.4-0.1-0.30.00.9
Patch foraging indifference point 0 sec2.64.111.5-3.4-3.0-2.8-2.22.7-2.0-1.81.7-2.3-1.4-1.41.52.2-2.2-1.9-1.10.50.91.1
Patch foraging indifference point AUC1.01.13.1-0.7-1.7-1.3-1.01.8-1.2-1.01.0-0.3-1.1-1.11.30.9-0.9-0.90.3-0.5-0.40.7
Delay disc. indifference point, 0s delay0.20.31.41.20.10.90.70.30.20.5-0.50.00.40.4-0.4-0.30.30.2-0.00.10.10.8
Delay disc. indifference point, 16s delay0.50.63.90.6-0.20.40.50.9-0.10.2-0.2-1.30.70.7-0.2-0.20.2-0.2-0.80.90.82.0
Delay disc. indifference point, 2s delay0.70.81.8-0.5-0.7-0.7-0.81.3-1.3-0.90.9-0.6-0.5-0.50.91.3-1.3-1.10.1-0.4-0.01.2
Delay disc. indifference point, 24s delay1.01.05.3-0.7-1.0-0.8-0.41.4-0.9-0.60.6-1.7-0.1-0.10.60.7-0.7-1.1-0.80.90.82.3
Delay disc. indifference point, 4s delay0.50.51.81.30.61.10.9-0.10.70.9-0.9-0.20.70.7-0.8-0.60.60.9-0.40.40.50.5
Delay disc. indifference point, 8s delay0.50.52.81.20.20.80.80.70.10.4-0.4-0.90.70.7-0.4-0.30.30.0-0.50.80.61.7
Indifference point function ln k1.01.42.70.21.20.91.0-1.21.31.4-1.4-1.41.21.2-1.5-0.50.51.1-1.61.61.6-0.2
Indifference point function log k1.01.42.70.21.20.91.0-1.21.31.4-1.4-1.41.21.2-1.5-0.50.51.1-1.61.61.6-0.2
Patch foraging total patch changes 0 sec2.64.29.9-3.1-3.1-2.8-2.22.8-2.1-1.91.9-2.1-1.5-1.51.62.3-2.3-1.9-0.80.40.61.1
Patch foraging total patch changes 12 sec4.45.712.5-2.9-3.5-3.1-2.83.4-2.8-2.62.6-0.6-2.3-2.32.32.6-2.6-2.40.5-1.1-0.70.4
Patch foraging total patch changes 18 sec1.51.97.0-1.7-2.6-1.9-1.42.4-1.3-1.51.3-1.0-1.2-1.21.11.1-1.1-1.0-0.30.10.20.0
Patch foraging total patch changes 24 sec2.32.86.7-2.3-2.6-2.2-1.62.5-1.8-1.51.5-2.0-1.1-1.21.41.7-1.7-1.6-0.80.40.71.3
Patch foraging total patch changes 6 sec2.03.09.1-3.0-2.3-2.4-2.02.1-1.8-1.71.6-1.6-1.6-1.61.41.8-1.8-1.6-0.7-0.00.50.6
Patch foraging time to switch 0 sec0.30.41.90.80.60.60.3-0.70.30.1-0.01.40.00.0-0.3-0.90.90.30.8-0.5-0.8-1.0
Patch foraging water rate 0 sec1.21.94.6-2.1-1.5-1.9-1.51.2-1.5-1.41.4-1.4-0.9-0.91.31.8-1.8-1.6-0.30.20.21.4
Patch foraging water rate 12 sec1.11.63.80.21.70.91.2-1.71.21.1-1.2-1.61.41.4-1.2-0.70.70.7-1.52.01.60.8
Patch foraging water rate 18 sec0.71.03.1-0.61.00.30.5-1.30.70.8-0.9-1.80.80.8-0.9-0.20.20.4-1.61.51.60.3
Patch foraging water rate 24 sec0.20.31.0-0.10.70.40.4-0.60.40.3-0.4-0.90.50.5-0.6-0.40.40.5-1.00.81.0-0.3
Patch foraging water rate 6 sec0.50.71.80.20.80.50.7-0.90.60.7-0.7-1.30.90.9-0.7-0.40.40.2-1.11.41.10.5
Seeking ratio, delayed vs. immediate footshock0.10.10.4-0.1-0.4-0.10.10.4-0.10.00.0-0.60.30.30.1-0.10.1-0.3-0.40.50.40.5
Distance traveled before self-admin0.70.72.11.10.91.20.9-0.40.90.9-0.90.20.40.4-0.9-1.21.21.5-0.30.20.4-1.1
Distance traveled after self-admin0.70.83.00.40.30.80.7-0.41.11.0-1.00.10.40.5-1.0-1.01.01.7-0.60.10.6-1.7
Extensor digitorum longus weight0.51.88.62.50.91.21.1-0.3-0.00.3-0.21.91.11.1-0.20.0-0.0-1.52.1-0.2-1.92.9
Bone: elastic displacement2.42.74.21.11.91.71.7-2.01.92.0-2.0-1.21.71.7-1.8-1.71.71.5-1.61.51.70.2
Bone: elastic work0.20.31.0-0.50.6-0.20.1-1.00.20.4-0.4-1.00.30.3-0.10.0-0.0-0.2-0.80.80.70.8
Bone: endosteal estimation11.324.646.0-6.8-5.6-6.3-6.44.7-5.1-5.55.51.2-5.9-5.95.25.3-5.3-3.42.3-4.4-2.5-2.0
Bone: endosteal perimeter11.223.237.5-6.1-5.8-6.1-6.15.4-5.2-5.45.40.6-5.7-5.65.35.1-5.1-3.41.9-3.9-2.2-1.1
Epididymis fat weight1.12.57.1-0.5-1.7-1.6-1.21.2-1.9-2.02.00.5-1.1-1.12.01.2-1.2-2.71.5-0.4-1.52.3
Delta time in closed arm before/after self-admin0.20.20.6-0.30.1-0.3-0.50.0-0.3-0.40.30.6-0.4-0.40.30.5-0.50.10.6-0.7-0.6-0.6
Delta time in open arm before/after self-admin0.50.41.81.30.10.90.90.50.30.6-0.5-0.30.70.7-0.4-0.70.70.1-0.30.60.31.1
Diff in mean of infusions in LGA sessions1.21.32.31.41.01.21.4-1.41.41.2-1.2-0.31.00.9-1.3-1.51.50.9-0.71.30.8-0.3
Delay discount exponential model param0.30.33.0-0.30.40.00.1-1.20.60.3-0.30.7-0.0-0.0-0.3-0.50.50.40.3-0.2-0.3-1.7
Extinction: sum of active levers before priming0.20.21.3-0.2-0.9-0.2-0.11.2-0.2-0.10.0-0.3-0.0-0.00.20.2-0.2-0.4-0.20.20.10.7
Active lever presses in extinction session 60.70.72.2-1.3-1.5-1.2-1.01.2-0.7-0.70.6-0.1-0.8-0.80.60.6-0.6-0.60.1-0.3-0.20.0
Bone: final force0.71.24.5-2.1-0.3-1.5-1.20.2-0.8-0.80.7-1.7-0.8-0.80.81.5-1.5-0.7-1.00.50.90.4
Bone: final moment0.71.24.8-2.2-0.3-1.5-1.20.1-0.9-0.80.7-1.7-0.8-0.80.91.5-1.5-0.8-1.00.40.90.3
Food consumed during 24 hour testing period1.11.44.2-1.2-2.0-1.7-1.11.7-1.3-1.31.3-0.2-1.0-1.01.30.6-0.6-1.60.40.1-0.51.0
Glucose0.81.22.31.31.31.31.2-1.51.21.1-1.10.21.01.1-1.1-1.51.51.2-0.40.40.4-0.5
Heart weight0.50.72.20.50.20.60.7-0.00.60.9-0.9-1.51.11.1-0.8-0.30.30.6-1.31.01.40.4
Delay discount hyperbolic model param0.30.32.8-0.40.4-0.00.0-1.10.50.2-0.20.8-0.1-0.1-0.2-0.40.40.40.4-0.2-0.4-1.7
Intermittent access intake day 1-15 change1.71.64.0-0.9-0.4-0.9-1.20.4-0.9-1.21.12.0-1.4-1.41.21.3-1.3-0.81.9-1.8-1.9-0.8
Intermittent access intake escalation0.90.92.7-0.6-0.1-0.5-0.80.2-0.6-0.80.81.7-0.9-0.90.91.0-1.0-0.61.5-1.5-1.5-0.6
Intermittent access intake escalation 23.13.15.1-1.5-0.7-1.5-1.80.6-1.6-1.81.72.1-2.0-2.01.92.0-2.0-1.52.2-2.2-2.3-0.5
Intermitt. access day 1 inactive lever presses1.11.24.7-2.2-2.0-1.7-1.31.5-0.7-0.70.6-1.4-0.8-0.70.60.4-0.40.0-1.20.31.0-0.7
Intermitt. access day 15 inactive lever presses0.70.81.8-1.2-1.3-1.3-1.10.9-0.9-1.00.90.1-1.0-1.00.80.7-0.7-0.80.4-0.3-0.5-0.1
Intermitt. access escalation Index2.22.04.21.62.01.81.5-1.81.71.4-1.70.80.80.8-1.9-1.51.51.9-0.00.50.1-0.9
Intermittent access day 1 total infusions0.70.84.2-0.5-0.9-0.30.10.9-0.10.1-0.1-2.00.40.3-0.1-0.50.5-0.2-1.61.51.61.1
Intermittent access day 15 total infusions0.30.30.8-0.9-0.8-0.7-0.60.8-0.6-0.50.5-0.3-0.4-0.40.50.5-0.5-0.7-0.10.00.00.2
Intermittent access terminal intake (last 3 days)1.81.93.1-1.7-1.7-1.8-1.61.6-1.7-1.61.7-0.0-1.5-1.51.51.4-1.4-1.60.5-0.7-0.60.4
Intermittent access total infusions1.21.33.5-1.8-1.9-1.6-1.31.6-1.2-1.01.0-1.3-0.9-0.91.00.8-0.8-1.0-0.70.30.60.5
Intermittent access day 1 locomotion1.31.34.2-1.5-2.1-1.5-1.11.6-1.1-0.80.8-1.8-0.6-0.70.70.6-0.6-1.0-1.10.71.01.0
Intermittent access day 15 total locomotion3.03.37.7-2.8-2.6-2.6-2.32.2-2.0-1.71.7-0.8-1.7-1.71.91.9-1.9-1.8-0.1-0.6-0.00.4
Intermittent access total locomotion3.84.411.2-3.2-3.4-3.1-2.52.6-2.2-1.81.8-1.9-1.6-1.61.82.1-2.1-2.2-0.80.10.71.1
Intermittent access standard deviation0.80.81.7-1.1-1.3-1.2-1.01.2-1.0-0.90.9-0.3-0.8-0.81.11.1-1.1-1.00.2-0.2-0.20.3
Left kidney weight2.26.213.10.61.51.72.2-1.72.42.5-2.5-3.42.72.7-2.4-2.32.32.2-3.63.53.60.1
Right kidney weight1.13.17.10.11.21.01.5-1.31.81.9-1.7-2.51.91.9-1.6-1.51.51.5-2.62.72.6-0.1
Cocaine induced anxiety0.30.30.70.00.80.50.5-0.70.60.7-0.6-0.70.80.8-0.6-0.10.10.6-0.70.50.8-0.2
Post-drug Anxiety0.30.41.71.30.91.00.8-0.70.40.6-0.5-0.00.91.0-0.2-0.10.10.3-0.10.00.10.0
Baseline Anxiety0.60.63.11.80.91.11.1-0.80.60.6-0.60.30.80.8-0.5-0.90.90.20.20.3-0.10.6
Tail length1.13.37.6-2.2-2.8-2.4-2.12.2-2.2-2.12.1-0.5-1.7-1.62.11.8-1.8-1.90.4-1.0-0.50.3
Length with tail1.24.47.0-2.5-2.6-2.7-2.62.5-2.5-2.32.4-0.1-2.4-2.42.62.1-2.1-1.70.7-1.5-0.8-0.1
Length without tail0.51.22.3-0.8-0.6-1.0-1.20.8-1.1-1.01.21.1-1.5-1.51.41.0-1.0-0.61.1-1.3-1.1-0.2
Times rat made contact with spout0.40.40.9-0.7-0.8-0.9-0.90.6-0.7-0.80.80.4-0.7-0.70.80.5-0.5-0.60.5-0.4-0.6-0.2
Lifetime Intake1.21.44.3-1.9-2.1-1.6-1.11.6-1.0-0.80.8-2.0-0.5-0.50.70.5-0.5-0.8-1.30.81.20.5
Liver weight, left0.40.71.5-0.7-0.8-1.0-1.01.0-1.0-0.90.90.2-1.1-1.01.20.7-0.7-0.60.4-0.8-0.5-0.2
Liver weight, right0.30.42.10.61.00.40.6-0.6-0.10.00.0-1.10.50.50.1-0.30.3-0.4-0.51.00.61.4
Locomotor activity1.52.38.7-1.6-0.3-0.30.4-0.51.31.2-1.3-2.80.80.8-1.3-0.70.71.4-3.02.22.8-1.1
Locomotor testing distance1.32.28.3-1.5-1.2-0.40.30.51.21.1-1.2-2.70.70.7-1.3-0.60.61.4-2.92.12.7-1.1
Locomotor testing rearing0.50.86.0-1.7-1.3-0.9-0.50.40.70.2-0.2-0.4-0.2-0.2-0.5-0.00.01.0-0.90.40.7-2.4
Locomotion in novel chamber0.10.11.1-0.20.20.2-0.1-0.20.10.1-0.1-0.1-0.0-0.0-0.3-0.30.30.7-0.4-0.20.4-1.1
Locomotion in novel chamber post-restriction2.53.04.5-1.9-1.4-1.9-2.11.6-2.1-2.02.10.3-2.0-2.02.02.1-2.1-1.60.9-1.4-0.90.5
Fecal boli incidents, locomotor time 10.10.10.30.50.10.40.10.5-0.10.1-0.10.50.10.1-0.1-0.10.10.10.4-0.5-0.40.4
Change in fecal boli incidents, locomotor task0.30.22.1-0.0-0.0-0.10.10.3-0.4-0.20.2-0.60.20.20.20.6-0.6-0.7-0.10.60.11.4
Time >=10cm from walls, locomotor time 11.41.44.30.71.71.31.1-2.11.41.1-1.10.10.90.9-1.0-1.51.51.6-0.60.30.6-1.1
Bouts of movement, locomotor time 10.10.10.80.30.50.30.3-0.50.10.1-0.10.10.30.3-0.1-0.20.2-0.60.20.3-0.10.9
Total resting periods, locomotor time 10.20.21.10.40.60.20.2-0.4-0.2-0.10.10.40.10.10.10.0-0.0-0.80.50.1-0.51.0
Rest time, locomotor task time 10.20.21.10.60.60.40.2-0.3-0.10.00.01.00.10.10.0-0.10.1-0.20.9-0.7-0.80.3
Distance moved, locomotor task time 10.20.20.6-0.4-0.7-0.7-0.50.3-0.5-0.70.7-0.2-0.5-0.50.70.3-0.3-0.60.1-0.0-0.20.4
Vertical activity count, locomotor time 10.10.10.3-0.5-0.3-0.5-0.40.0-0.3-0.50.4-0.2-0.5-0.50.30.3-0.3-0.2-0.00.1-0.0-0.3
Time >=10cm from walls, locomotor time 20.60.62.70.20.70.20.1-1.60.60.1-0.11.7-0.2-0.1-0.1-0.70.70.51.0-0.8-1.0-1.3
Bouts of movement, locomotor time 20.30.31.60.90.20.50.7-0.30.40.5-0.30.20.70.7-0.3-0.60.6-0.20.20.4-0.21.2
Total resting periods, locomotor time 20.50.51.11.10.40.80.9-0.40.60.8-0.6-0.01.01.0-0.5-0.90.90.1-0.10.60.11.0
Rest time, locomotor task time 22.02.37.92.81.92.42.0-0.91.21.4-1.40.81.71.7-1.3-1.81.81.10.30.3-0.10.1
Distance moved, locomotor task time 20.40.51.0-0.9-0.6-1.0-0.7-0.4-0.2-0.80.70.8-0.9-0.90.60.4-0.4-0.40.7-0.4-0.8-0.6
Vertical activity count, locomotor time 21.31.44.4-2.1-1.5-1.9-1.40.5-0.8-1.21.10.2-1.5-1.61.01.2-1.2-0.80.3-0.5-0.5-0.3
Light reinforcement 10.91.65.60.4-0.90.30.90.90.50.9-1.0-2.41.41.4-0.9-0.70.7-0.1-1.92.11.92.0
Light reinforcement 20.50.74.50.6-0.90.00.31.3-0.50.1-0.0-1.60.60.60.20.0-0.0-0.7-0.90.90.92.1
Bone: marrow area11.224.244.6-6.7-5.5-6.3-6.34.6-5.0-5.45.41.3-5.8-5.85.25.3-5.3-3.42.3-4.4-2.6-2.1
Bone: maximum diameter2.75.011.3-3.4-2.6-3.0-2.92.6-2.5-2.32.3-1.3-2.4-2.42.42.5-2.5-1.5-0.3-1.00.10.1
Bone: maximum force1.42.36.3-2.5-1.2-2.0-1.51.1-1.5-1.31.2-2.4-0.9-0.91.22.0-2.0-1.3-1.30.81.11.3
Bone: maximum moment1.42.46.8-2.6-1.2-2.1-1.61.1-1.5-1.31.3-2.3-1.0-1.01.32.0-2.0-1.4-1.10.61.01.2
Mean time between licks in bursts0.20.31.0-0.1-0.3-0.5-0.40.5-0.7-0.60.6-0.0-0.5-0.50.60.3-0.3-1.00.4-0.0-0.41.0
Mean num. licks in bursts0.20.31.00.1-0.6-0.5-0.40.9-0.7-0.60.5-0.1-0.2-0.20.50.4-0.4-0.90.30.0-0.31.0
Cd content in liver0.70.82.41.11.61.30.7-1.30.80.8-0.81.20.70.7-0.80.0-0.00.50.8-0.7-0.7-0.4
Co content in liver0.30.41.70.20.60.50.1-0.70.50.5-0.51.2-0.00.0-0.2-0.30.30.70.5-1.1-0.5-1.3
Cu content in liver0.20.20.7-0.2-0.6-0.4-0.40.8-0.6-0.50.50.3-0.3-0.30.40.3-0.3-0.70.5-0.3-0.40.6
Fe content in liver0.40.51.4-0.50.20.20.3-0.20.80.7-0.7-1.00.80.8-0.9-0.30.30.8-1.20.91.2-0.5
K content in liver0.40.40.9-0.8-0.7-0.7-0.90.8-0.7-0.70.60.3-0.9-0.90.80.4-0.4-0.10.2-0.9-0.3-0.5
Mg content in liver0.70.72.1-0.5-0.2-0.5-0.80.3-0.9-0.70.71.2-1.0-1.00.90.6-0.6-0.71.1-1.4-1.1-0.1
Mn content in liver0.20.20.9-0.50.2-0.1-0.2-0.00.00.3-0.1-0.9-0.0-0.0-0.10.2-0.20.4-0.90.30.9-0.4
Na content in liver0.60.61.90.3-0.60.40.30.50.60.8-0.9-0.70.10.1-0.6-1.01.01.4-1.20.21.1-1.2
Rb content in liver0.81.03.40.51.81.10.8-1.81.11.1-1.20.00.80.8-1.2-0.40.41.2-0.50.20.6-0.9
Se content in liver1.41.73.71.91.11.71.6-0.21.11.3-1.3-0.71.41.4-1.3-1.61.61.4-1.01.11.00.2
Sr content in liver0.10.10.2-0.3-0.1-0.3-0.1-0.4-0.2-0.30.3-0.5-0.2-0.20.4-0.10.1-0.2-0.30.10.2-0.0
Zn content in liver0.40.41.30.80.30.70.60.50.10.3-0.3-1.00.30.3-0.1-0.80.80.6-0.80.50.81.1
Bone: minimum diameter7.714.427.7-5.3-4.8-5.1-4.84.3-4.2-4.24.1-0.6-4.2-4.24.24.1-4.1-3.20.8-2.2-1.10.4
Time in familiar zone, hab. session 12.01.92.9-1.2-1.3-1.4-1.51.4-1.5-1.61.51.1-1.4-1.41.31.7-1.7-1.41.4-1.3-1.50.2
Time in novel zone, hab. session 11.81.72.61.11.41.31.5-1.61.51.4-1.5-0.91.31.3-1.3-1.61.61.1-1.11.41.2-0.0
Total zone transitions, hab. session 10.30.42.0-0.9-0.3-0.5-0.0-0.40.20.00.0-1.40.30.3-0.1-0.10.1-0.1-1.21.21.10.1
Total locomotion distance, hab. session 10.50.73.8-1.4-0.5-1.0-0.40.1-0.2-0.40.4-2.0-0.0-0.00.30.0-0.0-0.5-1.51.51.40.5
Locomotion velocity, hab. session 10.50.72.7-1.4-0.9-1.1-0.60.4-0.5-0.70.8-1.6-0.3-0.30.60.3-0.3-0.6-1.11.01.10.4
Time in familiar zone, hab. session 21.31.42.3-1.3-1.5-1.4-1.51.1-1.0-1.11.10.6-1.4-1.51.11.3-1.3-0.50.8-1.3-0.9-0.9
Time in novel zone, hab. session 20.70.72.41.01.51.01.0-1.00.40.4-0.5-0.50.90.9-0.5-0.90.9-0.0-0.31.00.41.1
Total zone transitions, hab. session 20.20.20.7-0.3-0.3-0.10.3-0.40.50.2-0.2-0.50.20.2-0.2-0.80.80.3-0.60.80.6-0.2
Total locomotion distance, hab. session 20.40.51.4-0.9-0.9-0.9-0.40.6-0.6-0.70.8-0.9-0.2-0.20.70.3-0.3-1.0-0.40.90.31.2
Locomotion velocity, hab. session 20.30.51.8-0.6-0.8-0.8-0.30.7-0.6-0.70.8-0.8-0.2-0.20.70.2-0.2-1.0-0.30.90.21.3
Novel to familiar place preference ratio0.60.62.6-1.6-0.4-1.0-1.00.3-0.8-0.70.6-0.7-0.6-0.60.80.8-0.8-0.9-0.3-0.20.30.3
Novelty place preference0.30.31.9-1.4-0.1-0.7-0.70.1-0.5-0.40.4-0.6-0.4-0.40.60.5-0.5-0.6-0.4-0.10.40.1
Time in novel zone, NPP test0.20.21.9-1.40.0-0.6-0.6-0.2-0.3-0.20.2-0.7-0.3-0.30.40.3-0.3-0.3-0.60.00.6-0.2
Total zone transitions, NPP test0.91.24.60.2-0.10.30.9-0.00.70.7-0.6-2.21.11.1-0.8-0.90.90.5-1.92.11.80.8
Total locomotion distance, NPP test0.40.51.4-1.0-0.7-1.0-0.50.5-0.6-0.80.9-1.2-0.3-0.30.60.5-0.5-0.7-0.61.10.50.6
Locomotion velocity, NPP test0.50.72.8-0.3-0.8-0.6-0.00.9-0.5-0.50.6-1.70.20.20.40.1-0.1-0.8-0.91.60.91.5
Intraocular pressure0.60.82.30.6-1.00.20.61.2-0.10.10.0-1.50.80.8-0.1-1.01.0-0.1-1.21.51.11.4
Delta distance traveled before/after self-admin0.70.81.30.10.20.50.8-0.71.11.1-1.1-0.81.01.0-1.1-0.90.91.0-1.11.11.0-0.4
Delta ambulatory time before/after self-admin0.10.10.2-0.3-0.4-0.10.10.20.30.3-0.3-0.40.40.4-0.30.0-0.00.1-0.40.50.40.1
Parametrial fat weight1.53.05.7-1.2-0.6-1.5-1.71.1-2.2-2.02.01.0-1.7-1.82.21.8-1.8-2.41.8-1.6-1.71.7
Pavlov. Cond. lever latency0.50.62.21.11.10.50.2-0.3-0.5-0.50.41.2-0.1-0.10.20.3-0.3-0.81.5-0.6-1.31.1
Pavlov. Cond. magazine entry latency0.70.93.9-1.8-2.0-1.3-1.01.4-0.5-0.40.4-1.1-0.6-0.60.60.2-0.20.1-1.2-0.11.0-0.9
Pavlov. Cond. change in total contacts0.60.62.5-1.4-1.6-0.8-0.60.90.10.3-0.1-1.0-0.2-0.20.10.1-0.10.5-1.30.21.1-1.0
Pavlov. Cond. index score0.60.83.0-1.6-1.7-1.0-0.71.1-0.10.10.1-1.3-0.3-0.30.3-0.10.10.5-1.50.21.3-1.0
Pavlov. Cond. latency score0.60.72.4-1.3-1.5-0.8-0.40.90.20.3-0.2-1.3-0.1-0.10.1-0.30.30.7-1.50.41.4-1.0
Pavlov. Cond. lever contacts0.30.41.7-0.8-1.1-0.4-0.10.30.60.5-0.4-0.40.10.1-0.2-0.30.30.8-0.90.20.7-1.3
Pavlov. Cond. magazine entry number0.60.72.71.51.60.80.7-1.30.30.0-0.11.20.40.4-0.30.0-0.0-0.31.40.0-1.30.7
Pavlov. Cond. intertrial magazine entries1.01.34.2-1.3-1.6-1.2-0.81.8-1.0-0.70.6-2.0-0.1-0.20.41.1-1.1-1.0-1.20.91.21.0
Pavlov. Cond. lever-magazine prob. diff.0.60.72.5-1.4-1.6-0.8-0.51.00.10.2-0.1-1.4-0.2-0.20.2-0.20.20.6-1.60.41.4-0.9
Pavlov. Cond. response bias0.60.82.6-1.5-1.6-0.8-0.61.10.00.2-0.1-1.3-0.2-0.20.1-0.10.10.6-1.50.21.4-1.0
Pavlov. Cond. lever latency0.30.41.70.90.60.30.1-0.2-0.4-0.40.51.2-0.1-0.10.4-0.10.1-0.71.3-0.3-1.20.9
Pavlov. Cond. magazine entry latency1.82.13.81.81.81.81.6-1.91.71.5-1.50.41.11.1-1.5-1.61.61.9-0.40.30.5-1.5
Pavlov. Cond. change in total contacts0.20.31.8-0.5-0.7-0.3-0.30.50.10.2-0.2-0.4-0.3-0.3-0.10.3-0.30.8-0.6-0.30.5-1.4
Pavlov. Cond. index score0.40.62.3-0.00.20.40.4-0.60.90.8-0.9-0.50.40.3-0.9-0.50.51.3-1.00.20.9-1.5
Pavlov. Cond. latency score0.60.82.90.10.40.60.6-0.81.11.0-1.0-0.50.50.5-1.0-0.70.71.6-1.10.31.0-1.7
Pavlov. Cond. lever contacts0.20.31.4-0.8-0.6-0.3-0.10.20.30.3-0.4-1.20.10.1-0.40.1-0.10.4-1.20.41.1-0.5
Pavlov. Cond. magazine entry number2.63.25.3-1.9-2.2-2.2-1.92.3-2.1-1.92.0-0.1-1.5-1.52.01.9-1.9-2.30.8-0.7-0.91.6
Pavlov. Cond. intertrial magazine entries10.113.120.6-3.4-4.5-4.4-4.04.4-4.4-4.24.10.6-3.7-3.74.13.7-3.7-4.22.2-2.2-2.42.0
Pavlov. Cond. lever-magazine prob. diff.0.40.62.10.10.40.50.5-0.70.90.8-0.9-0.50.40.4-0.9-0.50.51.3-0.90.20.9-1.5
Pavlov. Cond. response bias0.20.20.8-0.4-0.1-0.00.1-0.20.40.4-0.4-0.80.20.1-0.40.0-0.00.6-0.90.30.8-0.9
Time in closed arm before self-admin1.72.03.10.31.31.01.3-1.81.71.6-1.6-1.11.41.4-1.6-1.61.61.4-1.61.41.6-0.5
Time in closed arm after self-admin0.50.52.5-0.21.20.30.2-1.60.70.3-0.40.70.00.0-0.5-0.60.60.90.2-0.4-0.2-1.3
Time in open arm before self-admin0.40.41.20.61.10.70.5-1.10.50.3-0.31.00.10.1-0.4-0.50.50.50.6-0.4-0.6-0.8
Time in open arm after self-admin0.20.21.60.6-0.60.20.11.3-0.5-0.20.30.2-0.0-0.00.40.1-0.1-0.50.4-0.1-0.40.9
Bone: periosteal estimation5.912.230.1-5.5-4.1-4.9-4.53.5-3.7-3.73.7-0.9-3.9-3.93.74.0-4.0-2.60.3-1.9-0.5-0.4
Bone: periosteal perimeter2.23.79.9-3.2-2.4-2.7-2.52.2-2.0-1.81.8-1.2-2.2-2.12.02.1-2.1-1.0-0.5-0.90.3-0.2
Bone: post-yield work2.02.74.6-2.1-1.6-2.1-2.11.3-1.7-1.91.90.2-1.9-1.81.82.1-2.1-1.20.8-1.3-0.9-0.4
Progressive ratio test 1 active lever presses1.31.45.7-1.8-2.4-1.5-1.01.6-0.8-0.60.7-1.9-0.6-0.60.70.2-0.2-0.7-1.40.91.30.3
Progressive ratio test 1 breakpoint1.61.77.8-1.8-2.8-1.7-1.02.0-0.9-0.70.8-2.1-0.5-0.50.80.1-0.1-0.8-1.51.01.40.5
Progressive ratio test 1 inactive lever presses1.71.86.4-2.3-2.4-1.7-1.01.8-0.7-0.70.4-2.5-0.5-0.50.30.1-0.1-0.4-2.01.31.80.2
Progressive ratio test 2 active lever presses1.92.06.1-1.9-2.5-1.8-1.62.3-1.7-1.41.4-1.3-1.1-1.11.51.1-1.1-1.2-0.6-0.20.50.6
Progressive ratio test 2 breakpoint2.22.56.9-2.1-2.6-2.0-1.92.3-1.9-1.71.6-0.9-1.5-1.41.71.4-1.4-1.4-0.2-0.50.20.4
Progressive ratio test 2 inactive lever presses2.32.76.1-2.5-2.3-2.1-1.82.3-1.9-1.61.4-1.8-1.3-1.31.51.4-1.4-1.6-0.90.20.81.2
Incentive Sensitization - Responses1.81.93.2-1.2-1.8-1.5-1.61.8-1.8-1.71.60.1-1.5-1.51.71.4-1.4-1.10.6-1.1-0.70.3
Incentive Sensitization - Breakpoint1.81.83.0-1.2-1.7-1.5-1.61.7-1.7-1.71.60.3-1.5-1.51.61.3-1.3-1.10.7-1.2-0.70.1
Sum of active levers in priming session hrs 5-61.11.12.20.20.31.01.0-0.61.41.5-1.5-0.51.21.2-1.4-0.90.91.3-1.10.91.1-0.4
Progressive ratio0.40.51.40.60.20.0-0.30.6-0.7-0.70.51.0-0.7-0.70.60.6-0.6-0.31.2-1.0-1.1-0.2
Food seeking constrained by brief footshock3.64.48.1-2.0-2.1-2.4-2.41.3-1.8-2.32.21.9-2.8-2.82.21.9-1.9-1.22.0-2.4-2.1-1.5
Seeking ratio, punishment vs. effort0.50.73.0-1.7-1.4-1.4-1.00.2-0.4-0.60.80.1-0.9-0.90.70.4-0.4-0.4-0.0-0.5-0.1-0.5
Retroperitoneal fat weight1.55.09.5-2.6-2.1-3.1-2.51.1-2.5-2.92.80.5-2.3-2.32.62.2-2.2-3.01.5-1.0-1.61.1
Reaction time number correct0.91.32.00.91.21.31.3-0.40.91.0-1.0-1.31.31.3-1.1-1.11.10.8-1.31.41.40.8
Reaction time mean minus median0.20.31.60.40.30.20.0-0.0-0.1-0.30.11.3-0.2-0.2-0.2-0.20.2-0.41.2-0.6-1.10.0
Reaction time mean minus median AUC0.30.41.20.31.00.80.6-0.50.50.5-0.8-0.10.60.5-1.1-0.70.70.2-0.20.50.30.3
Reaction time num false alarms1.01.44.5-1.9-2.1-1.5-1.12.1-0.7-0.51.0-1.6-0.6-0.50.90.7-0.70.1-1.30.41.1-0.6
Reaction time num false alarms AUC1.21.64.7-2.1-2.2-1.7-1.52.1-1.1-0.81.2-1.3-0.9-0.91.21.1-1.1-0.4-0.9-0.10.7-0.4
Reaction time trials correct on left0.91.32.00.91.21.31.3-0.40.91.0-1.0-1.31.31.3-1.1-1.11.10.8-1.31.41.40.8
Reaction time trials on left0.81.11.90.91.21.31.2-0.30.80.9-0.9-1.21.21.2-1.0-1.01.00.7-1.21.41.30.9
Reaction time mean0.20.31.10.10.90.60.2-0.90.40.3-0.50.60.20.2-0.7-0.50.50.50.3-0.4-0.2-1.1
Reaction time mean AUC0.40.51.70.11.00.70.4-1.20.70.5-0.70.80.40.4-0.9-0.70.70.70.3-0.4-0.2-1.3
Median of all reaction times0.20.31.6-0.10.90.50.2-1.10.50.4-0.60.30.30.3-0.7-0.50.50.7-0.1-0.30.2-1.3
Reaction time omissions0.60.81.8-0.4-0.1-0.7-0.80.7-1.1-1.21.10.6-0.8-0.80.90.8-0.8-1.31.1-0.5-1.01.0
Reaction time false alarm rate1.31.85.2-2.1-2.3-2.0-1.71.8-1.1-1.01.4-0.3-1.4-1.31.41.3-1.3-0.4-0.1-0.8-0.1-1.1
Reaction time premature initiation rate0.40.52.0-0.9-1.0-0.8-0.40.8-0.3-0.1-0.1-1.4-0.2-0.3-0.00.7-0.7-0.5-0.90.80.81.2
Reaction time premature initiations0.50.73.2-0.2-0.4-0.10.20.60.00.3-0.5-1.80.40.3-0.40.2-0.2-0.2-1.31.41.31.7
Std. dev. reaction times0.40.62.8-0.20.5-0.1-0.5-0.1-0.5-0.60.41.7-0.7-0.70.20.4-0.4-0.61.6-1.2-1.5-0.4
Reaction time trials completed0.81.11.90.91.21.31.2-0.30.80.9-0.9-1.21.21.2-1.0-1.01.00.7-1.21.41.30.9
Reaction time trials AUC0.70.91.60.81.21.21.1-0.40.70.8-0.8-1.11.11.1-0.9-0.90.90.6-1.11.31.20.8
Run reversals in cocaine runway, females0.60.62.11.30.80.40.4-1.20.1-0.3-0.11.40.10.1-0.10.0-0.0-0.81.4-0.3-1.40.7
Run reversals in cocaine runway, males0.10.10.20.20.30.30.10.2-0.00.2-0.2-0.40.10.1-0.20.2-0.20.0-0.30.00.30.4
Latency to leave start box in cocaine runway0.50.51.10.70.80.70.8-0.91.00.9-0.70.10.60.7-0.7-0.80.81.0-0.40.70.4-0.7
Latency to leave start box in cocaine runway, F1.92.13.91.01.11.41.5-1.01.81.7-1.5-1.01.41.4-1.5-1.61.62.0-1.61.51.6-0.9
Latency to leave start box in cocaine runway, M0.70.72.6-0.20.0-0.5-0.6-0.5-0.4-0.60.71.6-0.7-0.70.70.8-0.8-0.81.5-1.1-1.4-0.3
Std. dev. time between licks in bursts0.10.10.50.7-0.2-0.00.10.2-0.2-0.20.20.2-0.2-0.20.2-0.30.3-0.50.40.1-0.40.7
Total sessions with >9 infusions2.62.99.50.2-0.40.71.30.11.01.4-1.5-3.11.81.8-1.2-1.61.60.8-2.92.52.81.1
Short access day 1 total inactive lever presses0.40.52.6-1.1-0.8-0.7-0.40.5-0.3-0.30.1-1.6-0.1-0.10.1-0.00.0-0.1-1.20.91.10.4
Short access day 10 total inactive lever presses0.80.91.7-1.3-0.8-1.3-1.21.1-1.0-1.01.0-0.2-0.8-0.90.71.3-1.3-1.00.3-0.1-0.30.4
Short access day 1 total infusions2.83.012.6-0.9-1.10.10.80.80.81.1-1.2-3.51.51.5-1.1-1.41.40.7-3.32.73.20.4
Short access day 10 total infusions2.62.98.4-2.3-2.9-2.5-1.82.4-1.8-1.61.7-1.9-1.2-1.21.51.2-1.2-1.9-0.80.70.61.1
Short access total infusions1.51.77.5-2.0-2.0-1.2-0.61.4-0.20.0-0.0-2.70.10.1-0.1-0.30.3-0.0-2.31.62.2-0.1
Short access day 1 locomotion2.02.29.8-1.4-2.5-1.2-0.52.1-0.7-0.20.2-3.10.40.40.20.3-0.3-1.0-2.21.82.11.6
Short access day 10 total locomotion4.75.316.2-3.1-4.0-3.3-2.73.4-2.5-2.22.0-1.3-1.9-1.92.32.2-2.2-2.3-0.2-0.40.01.0
Short access total locomotion2.02.18.6-1.8-2.9-1.8-1.02.2-0.9-0.50.5-2.6-0.2-0.20.60.4-0.4-1.1-1.81.41.61.1
One hour access (0.3 mA shock)0.40.41.8-1.3-1.1-1.0-0.80.5-0.5-0.60.5-0.3-0.8-0.80.60.4-0.4-0.3-0.2-0.20.1-0.8
Compulsive drug intake0.90.93.30.41.81.00.8-1.61.11.0-1.00.20.50.4-1.3-0.70.71.3-0.30.50.4-1.1
One hour access (shock baseline)0.80.93.8-1.0-1.9-1.3-1.01.4-1.1-1.00.9-0.4-0.8-0.71.20.7-0.7-1.00.0-0.4-0.10.5
Social response proportion0.20.30.4-0.10.70.40.4-0.50.60.6-0.6-0.30.60.6-0.6-0.30.30.4-0.50.50.50.2
Social responses0.50.72.0-1.4-0.1-0.20.1-0.70.80.7-0.8-1.10.30.3-0.7-0.50.50.7-1.41.11.3-0.7
Social time0.10.21.00.40.20.40.1-0.00.20.0-0.21.00.00.0-0.2-0.00.00.40.7-0.6-0.6-0.8
Soleus weight0.41.23.60.2-0.30.60.80.40.81.1-1.1-1.81.11.2-0.9-0.80.81.1-1.91.31.80.3
Bone: stiffness0.81.24.3-2.1-1.0-1.6-1.30.8-1.0-1.01.0-1.4-0.9-0.90.81.5-1.5-0.7-0.80.30.60.1
Tibialis anterior weight0.20.74.7-0.2-1.1-0.6-0.41.0-0.8-0.60.60.3-0.2-0.20.80.4-0.4-1.70.7-0.1-0.82.2
Time to tail flick, vehicle, before self-admin0.50.51.90.10.60.1-0.4-0.2-0.4-0.40.41.1-0.7-0.70.40.9-0.90.11.0-1.4-1.0-0.5
Time to tail flick, vehicle, after self-admin0.91.03.4-0.1-1.0-0.6-0.81.8-1.4-1.01.1-0.1-0.7-0.71.11.3-1.3-1.00.6-0.7-0.51.1
Time to tail flick, test, before self-admin0.80.73.40.00.80.1-0.3-0.8-0.2-0.30.31.8-0.5-0.50.10.7-0.7-0.41.6-1.6-1.5-0.0
Time to tail flick, test, after self-admin0.20.20.4-0.20.10.30.30.40.20.4-0.5-0.60.60.6-0.4-0.10.10.1-0.60.50.60.6
Delta time to tail flick, vehicle, before/after SA1.91.93.9-1.0-1.7-1.6-1.42.0-1.7-1.61.70.1-1.2-1.21.61.5-1.5-1.80.9-0.7-0.91.0
Delta time to tail flick, test, before/after SA0.30.31.4-0.4-0.20.10.10.60.10.3-0.3-1.20.40.4-0.1-0.10.10.2-1.00.71.00.1
Tibia length0.61.76.60.30.60.71.0-0.30.81.1-1.0-2.61.21.2-1.0-0.90.91.1-2.31.92.30.3
Ambulatory time before self-admin0.50.51.50.90.60.90.7-0.40.70.6-0.60.20.20.2-0.6-1.21.21.2-0.30.10.3-1.0
Ambulatory time after self-admin0.40.41.3-0.0-0.10.40.40.00.70.7-0.7-0.50.50.5-0.7-0.80.81.1-0.80.40.8-0.9
Bone: tissue strength1.51.42.01.01.21.21.3-0.91.11.1-1.2-1.11.31.3-1.3-1.31.31.2-1.31.41.3-0.3
Total heroin consumption0.30.41.1-0.4-0.50.00.10.60.50.6-0.6-0.70.00.0-0.4-0.60.61.0-1.10.51.0-0.9
Bone: trabecular number0.71.22.1-1.0-1.2-1.3-1.21.5-1.4-1.31.2-0.6-1.2-1.21.21.3-1.3-0.80.0-0.4-0.10.4
Bone: trabecular spacing0.30.40.80.50.40.60.6-0.50.70.6-0.60.80.60.6-0.6-0.90.90.60.2-0.0-0.2-0.8
Bone: trabecular thickness1.31.52.6-0.9-1.2-1.4-1.31.5-1.6-1.31.3-0.4-1.1-1.21.41.6-1.6-1.50.4-0.5-0.51.6
Bone: trabecular tissue density1.11.55.11.21.21.01.3-0.50.60.8-0.7-1.81.41.4-0.8-0.70.70.2-1.22.01.32.3
Water consumed over 24 hours0.10.10.7-0.3-0.1-0.4-0.0-0.1-0.1-0.10.1-0.60.20.20.1-0.00.0-0.5-0.30.90.20.7
Number of responses in last shaping day0.60.62.5-0.9-0.9-0.30.00.80.20.5-0.3-1.60.50.5-0.5-0.50.50.2-1.51.11.50.1