Hub : Genes

Ngrn

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Ngrn 0.04 0.02 2.7e-04 0.03 0.03 0.02 0.02 4.9e-04 2.1e-04 9.7e-04 1.0e-03
2 NAcc gene expression Ngrn 0.11 0.05 1.4e-13 0.07 0.12 0.12 0.11 4.4e-09 1.1e-13 1.3e-13 4.2e-13
3 NAcc isoform ratio NR_028055.1 0.08 0.04 5.9e-06 0.05 0.05 0.05 0.06 4.4e-06 1.5e-06 1.4e-06 4.2e-07
4 NAcc isoform ratio NM_001033900.2 0.05 0.03 5.4e-05 0.03 0.04 0.04 0.04 7.3e-05 3.1e-05 2.5e-05 1.6e-05
5 Brain gene expression Ngrn 0.2 0.08 4.1e-15 0.12 0.17 0.15 0.14 8.7e-11 1.8e-15 5.1e-14 3.4e-13
6 PL isoform ratio NR_028055.1 0.04 0.03 3.7e-04 0.02 0.02 0.01 0.01 3.2e-03 1.5e-03 5.0e-02 1.4e-02
7 Brain isoform ratio NM_001033900.2 0.04 0.03 1.4e-03 0.04 0.03 0.04 0.04 9.2e-05 5.0e-04 2.7e-04 3.1e-04
8 BLA gene expression Ngrn 0.22 0.09 1.3e-08 0.05 0.13 0.12 0.11 7.7e-04 1.2e-07 6.0e-07 2.2e-06
9 PL gene expression Ngrn 0.21 0.07 0.0e+00 0.21 0.23 0.23 0.24 8.2e-23 1.5e-24 2.9e-25 1.2e-25
10 PL intron excision ratio chr1_134214206_134218343 0.06 0.03 7.0e-07 0.04 0.05 0.04 0.03 3.6e-05 5.9e-06 3.4e-05 1.4e-04
11 OFC gene expression Ngrn 0.12 0.08 9.6e-03 0.04 0.07 -0 0.04 4.4e-02 9.0e-03 3.4e-01 4.0e-02
12 BLA isoform ratio NR_028055.1 0.12 0.07 1.0e-04 0.08 0.08 0.07 0.09 3.3e-05 6.0e-05 1.5e-04 2.5e-05
13 Adipose isoform ratio NM_001033900.2 0.09 0.1 1.1e-03 0.01 0.01 0 0 4.3e-02 6.0e-02 1.4e-01 1.4e-01
14 Adipose isoform ratio NR_028055.1 0.05 0.04 1.4e-03 0.01 0.01 0 0.01 3.0e-02 6.7e-02 2.3e-01 3.1e-02
15 BLA isoform ratio NM_001033900.2 0.06 0.04 6.4e-03 0.04 0.03 0.01 0.03 5.4e-03 6.4e-03 5.0e-02 1.0e-02
16 Brain intron excision ratio chr1_134214206_134218343 0.04 0.03 5.6e-04 0.01 0.03 0.02 0.02 3.1e-02 3.5e-04 2.9e-03 4.0e-03
17 Brain isoform ratio NR_028055.1 0.06 0.03 1.6e-05 0.06 0.06 0.06 0.06 1.8e-06 2.7e-06 4.9e-06 3.5e-06
18 pVTA gene expression Ngrn 0.17 0.09 5.5e-05 0.04 0.03 0.03 0.05 6.6e-03 1.3e-02 1.5e-02 3.5e-03
19 pVTA isoform ratio NR_028055.1 0.11 0.08 4.7e-03 0.05 0.05 0.04 0.05 3.4e-03 3.3e-03 6.7e-03 3.7e-03
20 Adipose gene expression Ngrn 0.19 0.08 0.0e+00 0.1 0.12 0.11 0.12 1.8e-11 4.8e-13 1.9e-12 3.9e-13
21 NAcc mRNA stability Ngrn 0.02 0.02 3.4e-03 0.01 0.02 0.02 0.01 2.6e-02 4.4e-03 2.6e-03 7.5e-03
22 Liver gene expression Ngrn 0.06 0.04 1.4e-03 0.02 0.01 0.01 0.01 6.1e-03 1.8e-02 1.2e-02 9.4e-03
23 pVTA isoform ratio NM_001033900.2 0.11 0.09 7.1e-03 0.05 0.04 0.02 0.06 2.3e-03 4.9e-03 3.6e-02 2.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density2.64.36.4-2.4-2.3-2.32.2-2.2-2.2-2.5-2.3-2.5-2.2-2.2-2.2-2.12.1-2.2-2.02.5-2.2-1.5-1.41.6-0.50.4
Area under the delay curve0.30.31.60.50.60.2-0.10.60.50.60.40.30.40.9-0.1-0.10.1-0.10.7-0.60.20.31.3-1.2-0.00.2
BMI with tail3.310.514.23.83.43.6-3.63.73.63.53.33.53.42.93.53.7-3.73.43.2-3.33.52.62.1-2.51.8-2.0
BMI without tail1.32.77.61.82.71.0-0.92.11.81.02.32.11.22.81.51.6-1.61.41.6-0.91.30.91.5-2.3-0.70.2
Body weight0.41.52.81.10.91.1-0.90.91.20.70.70.81.50.81.51.7-1.71.41.4-0.61.31.71.4-1.31.2-1.6
Weight adjusted by age0.40.41.4-0.6-0.7-0.60.5-0.5-0.6-0.6-0.7-0.7-0.6-0.8-0.8-1.21.2-0.7-0.50.6-0.4-0.6-0.40.5-0.10.3
Bone surface3.76.58.9-2.8-2.3-3.03.0-2.5-2.7-3.0-2.4-2.8-2.8-2.0-2.9-2.82.8-2.8-2.52.9-2.9-2.2-1.71.7-1.51.4
Bone volume3.45.88.4-2.7-2.3-2.82.8-2.5-2.6-2.9-2.3-2.7-2.6-2.0-2.7-2.62.6-2.6-2.42.9-2.7-2.0-1.61.7-1.31.2
Breakpoint value in progressive ratio session0.80.92.10.91.20.7-0.61.01.10.61.41.40.71.41.00.2-0.21.10.9-0.60.90.81.3-1.20.20.1
Number of licking bursts0.91.02.3-1.0-1.0-0.90.7-1.0-1.1-0.7-0.7-0.8-1.1-0.9-1.0-0.90.9-1.0-1.30.6-1.0-1.3-1.51.4-0.90.8
Context. condit. distance diff. score0.50.71.3-0.9-0.6-1.01.0-0.6-0.7-1.1-0.6-0.9-1.0-0.5-0.9-1.11.1-0.8-0.71.1-1.0-0.6-0.30.3-0.40.6
Locomotion velocity, session 10.40.41.00.70.50.8-0.80.40.60.90.50.60.80.40.80.9-0.90.80.6-1.00.60.60.2-0.30.4-0.4
Locomotion distance, session 10.00.00.1-0.0-0.00.00.0-0.2-0.10.0-0.10.10.10.00.1-0.40.40.2-0.0-0.00.10.10.2-0.10.20.3
Locomotion velocity, session 20.20.20.40.50.50.3-0.20.30.40.50.40.40.60.70.30.3-0.30.30.6-0.50.30.60.6-0.50.2-0.0
Locomotion distance, session 20.10.10.4-0.3-0.3-0.40.4-0.5-0.5-0.3-0.4-0.2-0.2-0.2-0.3-0.60.6-0.3-0.40.2-0.4-0.3-0.20.5-0.20.5
Locomotion velocity, session 31.11.33.7-0.90.2-1.61.7-0.6-1.0-1.5-0.3-0.5-1.10.5-1.3-1.21.2-1.2-0.81.5-1.3-1.0-0.1-0.1-1.91.8
Locomotion distance, session 32.12.35.4-1.4-0.1-2.22.3-1.2-1.4-2.1-0.5-0.8-1.50.3-1.5-1.41.4-1.5-1.32.2-1.6-1.3-0.60.5-2.32.1
Stereotopy head waving bouts, day 32.42.86.0-1.9-2.5-1.51.4-2.0-1.8-1.6-2.4-2.2-1.4-2.4-1.7-1.71.7-1.7-1.41.6-1.6-1.0-0.81.20.5-0.5
Stereotopy head waving duration, day 30.30.31.00.70.80.6-0.61.00.60.60.90.8-0.00.60.40.3-0.30.40.1-0.60.3-0.5-0.2-0.5-0.60.7
Locomotion velocity, session 70.30.41.50.10.9-0.70.80.10.1-0.70.40.40.31.2-0.10.6-0.6-0.20.40.7-0.20.50.7-0.9-0.90.3
Locomotion distance, session 70.20.31.5-0.20.5-0.90.9-0.1-0.3-0.80.20.1-0.40.7-0.5-0.00.0-0.5-0.20.8-0.5-0.30.0-0.2-1.20.9
Stereotopy head waving bouts, day 72.02.33.4-1.7-1.5-1.71.7-1.4-1.6-1.8-1.6-1.7-1.7-1.4-1.7-1.41.4-1.7-1.51.8-1.8-1.3-1.10.9-0.80.6
Stereotopy head waving duration, day 70.30.40.9-0.5-0.0-0.90.9-0.2-0.5-0.9-0.3-0.5-0.70.0-0.7-0.40.4-0.8-0.50.9-0.8-0.7-0.3-0.3-1.00.8
Locomotion velocity, session 82.42.95.21.92.21.5-1.52.12.01.62.21.91.52.31.61.5-1.51.61.8-1.61.61.31.6-1.80.30.1
Locomotion distance, session 80.71.02.4-1.1-0.8-1.31.3-1.0-1.0-1.4-1.0-1.1-1.0-0.5-1.1-1.51.5-1.0-0.71.4-1.2-0.50.10.1-0.30.6
Degree of sensitization distance0.90.91.71.10.81.2-1.31.21.11.20.91.00.80.50.91.1-1.10.80.9-1.31.00.60.4-0.60.6-0.7
Degree of sensitization stereotypy0.40.41.0-0.7-0.4-0.90.9-0.5-0.6-1.0-0.7-0.8-0.6-0.3-0.7-0.40.4-0.8-0.41.0-0.8-0.3-0.0-0.2-0.40.1
Conditioned locomotion0.60.71.5-1.0-1.2-0.80.8-1.0-0.7-1.1-1.1-1.2-0.4-1.1-0.6-0.30.3-0.7-0.41.1-0.60.3-0.10.50.8-0.9
Cocaine response after cond. corrected0.40.41.70.4-0.10.7-0.70.10.50.40.10.40.7-0.40.80.8-0.80.80.5-0.40.80.80.00.31.2-1.3
Cocaine response after cond. not corrected0.50.61.00.60.30.8-0.80.50.80.60.50.60.90.20.90.8-0.80.90.7-0.60.91.00.4-0.31.0-1.0
Cocaine response before conditioning0.30.41.6-0.5-0.2-0.60.7-0.2-0.4-0.5-0.2-0.5-0.70.1-0.7-1.21.2-0.6-0.30.5-0.6-0.50.4-0.7-0.40.9
Saline control response0.70.93.0-0.40.6-1.21.5-0.4-0.4-0.90.0-0.4-0.41.3-0.9-1.11.1-0.8-0.00.9-0.8-0.11.3-1.7-1.31.3
Bone: connectivity density2.64.16.3-2.3-2.5-2.01.9-2.2-2.2-2.1-2.3-2.4-2.1-2.5-2.1-2.02.0-2.1-2.02.1-2.1-1.6-1.82.0-0.20.2
Bone: cortical apparent density2.63.45.21.81.22.0-2.01.41.92.01.21.32.31.11.92.2-2.21.82.1-2.01.82.31.7-1.31.8-2.2
Bone: cortical area5.27.912.7-3.3-2.8-3.53.6-3.3-3.0-3.4-3.0-3.5-2.6-2.1-3.2-3.23.2-3.2-2.33.4-3.2-1.5-0.81.2-0.90.7
Bone: cortical porosity0.10.10.40.30.30.3-0.40.50.10.10.20.5-0.2-0.00.30.3-0.30.3-0.2-0.10.3-0.6-0.50.0-0.40.4
Bone: cortical porosity0.10.10.60.10.3-0.0-0.10.4-0.0-0.20.10.4-0.4-0.00.10.0-0.00.1-0.30.30.1-0.8-0.5-0.1-0.60.6
Bone: cortical thickness1.42.34.4-1.9-1.8-1.81.9-2.0-1.6-1.9-1.8-2.1-1.2-1.3-1.6-1.41.4-1.6-1.01.9-1.7-0.3-0.40.60.0-0.3
Bone: cortical thickness1.01.14.6-0.9-1.8-0.20.1-1.5-1.0-0.4-1.5-0.9-0.2-2.1-0.20.0-0.0-0.2-0.90.4-0.3-0.1-1.42.21.2-1.3
Bone: cortical tissue density2.53.35.11.81.12.0-2.01.41.82.11.21.32.31.01.92.2-2.21.82.1-2.01.82.21.6-1.21.9-2.2
Condit. Reinf. active minus inactive responses0.30.31.2-0.3-0.5-0.30.4-0.5-0.1-0.4-0.8-0.80.3-0.3-0.3-0.20.2-0.30.50.2-0.40.91.0-0.50.8-1.1
Condit. Reinf. active-inactive response ratio2.32.54.2-1.7-1.3-2.01.9-1.6-1.7-1.8-1.5-1.8-1.6-1.0-1.9-1.71.7-2.0-1.41.6-2.1-1.3-0.80.9-1.21.0
Condit. Reinf. active responses0.30.41.90.0-0.30.1-0.0-0.10.3-0.1-0.5-0.50.7-0.20.10.2-0.20.10.8-0.10.01.21.3-0.71.3-1.4
Condit. Reinf. inactive responses0.81.01.80.90.61.0-1.00.91.10.80.60.81.20.61.00.9-0.91.01.3-0.81.11.31.2-1.01.3-1.1
Incentive salience index mean0.70.84.80.20.1-0.00.2-0.00.5-0.1-0.3-0.51.10.60.20.4-0.40.11.3-0.10.01.82.2-1.61.3-1.6
Condit. Reinf. lever presses2.43.211.31.31.50.9-0.61.11.70.80.90.62.22.01.31.7-1.71.22.6-0.81.13.03.4-3.01.6-2.1
Condit. Reinf. active minus inactive responses0.60.82.20.70.50.8-0.80.70.80.60.30.51.00.40.90.5-0.51.01.1-0.51.01.11.5-1.21.3-0.9
Condit. Reinf. active-inactive response ratio1.11.12.61.00.31.4-1.40.91.01.10.30.81.20.01.30.8-0.81.41.1-1.11.31.00.9-0.61.6-1.3
Condit. Reinf. active responses0.30.43.00.30.40.10.00.20.40.10.20.10.50.80.2-0.10.10.30.8-0.00.30.91.7-1.50.5-0.2
Condit. Reinf. inactive responses0.91.13.1-0.80.2-1.61.8-0.8-0.7-1.2-0.3-0.9-0.61.0-1.3-1.21.2-1.3-0.21.2-1.3-0.11.2-1.3-1.21.2
Condit. Reinf. lever presses1.01.35.71.02.00.2-0.01.31.00.41.81.30.32.40.50.3-0.30.50.7-0.40.50.11.2-1.9-1.41.5
Condit. Reinf. lever reinforcers received0.30.43.60.20.50.00.10.20.40.10.2-0.00.60.90.1-0.20.20.20.8-0.00.20.91.9-1.70.5-0.2
Conditioned reinforcement - actives0.00.00.10.1-0.20.3-0.30.20.10.3-0.2-0.20.1-0.30.10.1-0.10.10.1-0.3-0.10.0-0.20.3-0.0-0.3
Conditioned reinforcement - inactives1.61.84.2-1.6-2.0-1.11.1-1.7-1.5-1.0-1.7-1.7-1.2-2.0-1.3-1.21.2-1.3-1.31.0-1.1-0.8-1.41.6-0.60.5
Conditioned locomotion0.10.10.30.30.10.5-0.60.50.50.20.50.50.1-0.20.50.2-0.20.50.1-0.20.40.1-0.50.50.1-0.2
Patch foraging indifference point 0 sec0.30.51.2-0.5-0.0-1.01.1-0.4-0.4-0.60.0-0.4-0.80.4-1.1-0.80.8-1.1-0.50.4-0.7-0.60.3-0.3-0.81.0
Patch foraging indifference point AUC2.32.64.5-1.7-1.6-1.61.5-1.4-1.8-1.8-1.6-1.5-2.0-1.5-1.5-2.12.1-1.4-1.81.8-1.6-1.8-1.01.1-1.01.3
Delay disc. indifference point, 0s delay0.20.21.0-0.3-0.80.1-0.2-0.4-0.2-0.0-0.7-0.70.0-0.90.0-0.30.30.1-0.0-0.0-0.10.30.00.41.0-0.7
Delay disc. indifference point, 16s delay0.10.20.70.10.3-0.40.40.1-0.10.10.00.0-0.20.4-0.8-0.30.3-0.9-0.1-0.1-0.2-0.50.3-0.3-0.60.7
Delay disc. indifference point, 2s delay0.30.31.50.41.0-0.30.30.70.40.10.70.5-0.01.2-0.4-0.10.1-0.40.4-0.2-0.0-0.20.7-1.0-0.90.8
Delay disc. indifference point, 24s delay0.20.20.4-0.4-0.4-0.50.5-0.5-0.6-0.3-0.6-0.4-0.3-0.3-0.6-0.40.4-0.6-0.40.3-0.4-0.4-0.10.3-0.40.2
Delay disc. indifference point, 4s delay0.40.42.60.40.8-0.10.30.20.30.40.30.20.51.4-0.1-0.20.2-0.10.8-0.4-0.10.61.6-1.5-0.50.3
Delay disc. indifference point, 8s delay0.70.81.61.00.81.0-0.91.00.91.10.70.80.80.90.80.3-0.30.91.0-1.00.70.71.3-1.30.3-0.3
Indifference point function ln k1.21.73.51.51.71.2-1.11.41.41.31.91.81.21.51.21.8-1.81.10.9-1.31.40.70.1-0.50.0-0.1
Indifference point function log k1.21.73.51.51.71.2-1.11.41.41.31.91.81.21.51.21.8-1.81.10.9-1.31.40.70.1-0.50.0-0.1
Patch foraging total patch changes 0 sec0.50.81.9-0.7-0.1-1.21.3-0.4-0.6-0.8-0.0-0.4-1.10.3-1.2-1.01.0-1.3-0.80.7-0.9-1.0-0.1-0.0-1.21.4
Patch foraging total patch changes 12 sec5.87.510.6-3.1-3.2-2.82.7-3.0-3.0-2.7-3.0-3.0-2.9-3.0-2.9-3.33.3-2.8-2.82.7-2.6-2.3-1.82.2-0.81.2
Patch foraging total patch changes 18 sec4.15.26.8-2.6-2.4-2.52.5-2.4-2.4-2.3-2.1-2.4-2.6-2.1-2.6-2.62.6-2.5-2.42.2-2.3-2.1-1.61.7-1.31.5
Patch foraging total patch changes 24 sec1.92.34.2-1.7-1.0-2.02.0-1.3-1.3-1.9-0.9-1.3-1.9-0.5-1.8-2.02.0-1.7-1.31.8-1.6-1.2-0.30.2-1.31.5
Patch foraging total patch changes 6 sec1.31.94.2-1.4-1.0-1.71.8-1.1-1.3-1.5-1.3-1.5-1.4-0.4-1.7-2.12.1-1.7-0.91.5-1.5-0.90.7-0.4-0.81.1
Patch foraging time to switch 0 sec1.32.03.1-1.6-1.7-1.51.5-1.8-1.6-1.2-1.5-1.6-1.4-1.3-1.7-1.71.7-1.7-1.41.2-1.5-1.0-0.91.0-0.70.7
Patch foraging water rate 0 sec1.52.44.11.81.91.6-1.62.01.81.21.71.81.41.51.91.8-1.81.81.5-1.21.71.11.1-1.20.6-0.7
Patch foraging water rate 12 sec9.214.118.74.14.33.7-3.64.24.23.53.93.73.94.24.13.9-3.94.04.2-3.43.53.53.6-3.81.7-1.9
Patch foraging water rate 18 sec5.37.113.03.13.62.3-2.33.43.02.23.13.02.53.42.73.0-3.02.62.8-2.12.42.02.2-2.80.3-0.8
Patch foraging water rate 24 sec3.14.46.72.31.92.4-2.42.12.32.22.02.02.31.62.42.6-2.62.42.1-2.22.21.91.1-1.21.3-1.5
Patch foraging water rate 6 sec5.07.411.63.02.92.7-2.72.93.02.62.82.72.92.72.93.4-3.42.82.9-2.42.62.62.1-2.31.4-2.0
Seeking ratio, delayed vs. immediate footshock1.41.68.4-0.6-2.20.3-0.4-1.2-0.50.3-2.4-1.90.7-2.1-0.20.2-0.2-0.30.6-0.2-0.31.40.50.52.0-2.9
Distance traveled before self-admin0.30.30.9-0.6-0.8-0.30.5-0.9-0.2-0.1-0.5-0.90.1-0.2-0.3-0.60.6-0.20.30.1-0.11.01.0-0.40.9-0.3
Distance traveled after self-admin2.62.95.0-2.1-1.9-2.02.0-2.2-2.0-1.5-2.2-2.2-1.5-1.2-2.0-1.91.9-2.0-1.21.5-2.1-0.8-0.40.8-1.20.8
Extensor digitorum longus weight0.31.22.61.21.50.7-0.61.31.30.81.31.11.01.60.91.3-1.30.81.3-0.80.81.11.2-1.5-0.0-0.4
Bone: elastic displacement2.22.58.81.1-0.41.9-2.00.30.91.8-0.40.52.1-0.81.61.8-1.81.61.3-1.81.61.80.60.42.8-3.0
Bone: elastic work0.30.42.6-0.1-0.70.2-0.1-0.7-0.20.1-0.9-0.40.7-0.70.20.5-0.50.20.3-0.10.20.90.20.41.2-1.6
Bone: endosteal estimation4.910.614.1-3.4-2.8-3.53.4-3.1-3.6-3.5-2.9-3.0-3.7-2.7-3.5-3.73.7-3.4-3.63.5-3.4-3.5-2.82.7-2.42.6
Bone: endosteal perimeter3.57.29.4-2.9-2.6-2.92.9-2.7-3.0-3.0-2.8-2.8-2.9-2.5-2.9-3.13.1-2.8-2.83.0-2.8-2.5-1.82.0-1.41.6
Epididymis fat weight1.84.27.91.70.72.5-2.31.21.81.90.61.12.50.52.72.0-2.02.82.3-1.62.22.72.2-1.72.8-2.8
Delta time in closed arm before/after self-admin0.20.20.70.50.10.7-0.80.60.30.2-0.30.50.4-0.40.70.3-0.30.70.4-0.10.60.10.4-0.30.8-0.4
Delta time in open arm before/after self-admin0.60.62.00.71.10.5-0.40.60.80.81.10.50.81.40.50.9-0.90.50.8-0.80.40.90.9-0.80.2-0.4
Diff in mean of infusions in LGA sessions1.61.83.3-1.4-0.8-1.61.7-1.3-1.5-1.4-1.1-1.1-1.5-0.4-1.6-1.41.4-1.6-1.21.3-1.6-1.3-0.70.6-1.81.3
Delay discount exponential model param0.30.31.9-0.5-0.7-0.1-0.0-0.5-0.4-0.5-0.4-0.3-0.4-1.00.20.2-0.20.2-0.70.6-0.2-0.4-1.41.30.2-0.3
Extinction: sum of active levers before priming0.90.91.80.80.60.9-0.80.91.10.50.60.81.00.51.10.6-0.61.21.2-0.51.01.31.4-0.91.2-1.0
Active lever presses in extinction session 61.71.62.61.30.71.6-1.51.21.51.51.01.01.50.61.50.9-0.91.51.5-1.41.41.61.2-0.71.5-1.3
Bone: final force2.33.86.0-2.3-1.9-2.32.5-2.1-2.0-2.3-2.0-2.3-2.0-1.5-2.2-2.42.4-2.2-1.72.3-2.2-1.2-0.60.9-0.70.7
Bone: final moment2.13.45.3-2.1-1.9-2.22.3-2.0-1.9-2.2-1.9-2.2-1.8-1.5-2.1-2.32.3-2.0-1.52.2-2.1-1.1-0.60.9-0.60.6
Food consumed during 24 hour testing period1.82.24.6-1.5-1.1-1.61.6-1.3-1.5-1.6-1.0-1.1-1.8-1.0-1.4-2.12.1-1.3-1.71.7-1.3-1.7-0.80.8-1.01.6
Glucose0.50.72.10.90.31.4-1.40.80.71.20.60.90.7-0.11.20.6-0.61.20.4-1.21.10.2-0.00.30.9-0.5
Heart weight0.71.12.31.10.41.5-1.51.01.11.20.70.91.10.11.30.7-0.71.41.0-1.11.20.90.5-0.51.5-0.9
Delay discount hyperbolic model param0.40.41.9-0.5-0.8-0.1-0.1-0.6-0.5-0.5-0.5-0.4-0.4-1.10.20.2-0.20.2-0.70.6-0.1-0.3-1.41.40.4-0.4
Intermittent access intake day 1-15 change0.40.41.1-0.8-0.8-0.70.7-0.7-0.7-0.4-0.7-1.1-0.6-0.5-0.9-0.70.7-0.9-0.50.3-0.7-0.3-0.20.3-0.20.5
Intermittent access intake escalation0.40.41.4-0.7-0.9-0.60.5-0.8-0.7-0.4-1.0-1.2-0.6-0.7-0.8-0.60.6-0.8-0.40.4-0.7-0.4-0.20.5-0.20.3
Intermittent access intake escalation 21.31.32.1-1.4-1.5-1.21.1-1.3-1.2-1.0-1.3-1.4-1.2-1.2-1.3-1.21.2-1.4-1.00.9-1.1-0.7-0.80.9-0.70.7
Intermitt. access day 1 inactive lever presses1.41.53.70.8-0.31.5-1.30.00.71.8-0.3-0.41.7-0.11.00.7-0.71.11.4-1.51.01.81.8-1.21.9-1.4
Intermitt. access day 15 inactive lever presses0.20.21.0-0.3-1.0-0.00.0-0.7-0.40.2-1.0-0.70.2-0.9-0.4-0.20.2-0.40.1-0.1-0.10.40.10.00.3-0.5
Intermitt. access escalation Index0.00.00.10.10.20.00.1-0.1-0.00.30.0-0.10.20.3-0.10.2-0.2-0.10.1-0.2-0.10.10.3-0.30.1-0.1
Intermittent access day 1 total infusions0.10.10.3-0.4-0.6-0.20.2-0.3-0.1-0.3-0.2-0.4-0.2-0.5-0.1-0.10.1-0.1-0.10.2-0.10.2-0.50.4-0.1-0.2
Intermittent access day 15 total infusions0.10.10.6-0.4-0.7-0.10.0-0.4-0.1-0.1-0.4-0.8-0.0-0.5-0.10.0-0.0-0.20.00.0-0.20.4-0.20.40.1-0.4
Intermittent access terminal intake (last 3 days)0.30.30.8-0.8-0.8-0.70.6-0.7-0.4-0.7-0.6-0.9-0.5-0.6-0.6-0.30.3-0.7-0.40.5-0.60.0-0.60.6-0.5-0.1
Intermittent access total infusions0.10.10.4-0.3-0.6-0.1-0.0-0.30.0-0.2-0.4-0.6-0.0-0.60.00.1-0.10.00.00.1-0.10.5-0.30.40.1-0.5
Intermittent access day 1 locomotion0.10.10.4-0.3-0.5-0.10.1-0.5-0.1-0.2-0.3-0.40.1-0.40.00.3-0.3-0.00.00.1-0.10.6-0.30.30.0-0.6
Intermittent access day 15 total locomotion0.10.10.9-0.0-0.30.0-0.2-0.10.10.1-0.4-0.30.4-0.00.00.5-0.5-0.10.6-0.1-0.10.80.3-0.30.0-0.9
Intermittent access total locomotion0.40.40.8-0.8-0.9-0.70.6-0.8-0.6-0.7-0.8-0.8-0.6-0.8-0.6-0.30.3-0.6-0.60.7-0.7-0.2-0.80.8-0.6-0.1
Intermittent access standard deviation3.63.95.8-2.3-2.4-1.91.8-2.3-2.1-1.8-1.9-2.3-2.1-2.1-1.9-2.02.0-1.8-2.21.6-1.8-1.6-1.92.0-1.31.5
Left kidney weight0.10.41.80.4-0.50.8-1.00.20.30.7-0.5-0.30.6-0.90.40.3-0.30.40.5-0.60.40.50.30.11.3-1.1
Right kidney weight0.10.30.80.70.20.8-0.90.60.60.80.20.40.60.00.50.4-0.40.60.6-0.70.60.40.6-0.40.7-0.6
Cocaine induced anxiety0.20.20.5-0.4-0.4-0.40.3-0.3-0.5-0.3-0.5-0.5-0.6-0.3-0.5-0.70.7-0.4-0.40.5-0.4-0.6-0.10.1-0.50.6
Post-drug Anxiety0.10.20.8-0.4-0.5-0.20.2-0.4-0.2-0.2-0.7-0.9-0.1-0.2-0.2-0.30.3-0.20.30.4-0.20.40.7-0.6-0.0-0.2
Baseline Anxiety1.61.75.00.90.80.9-0.80.61.20.90.60.61.71.11.11.6-1.61.01.7-0.91.02.21.6-1.51.2-2.0
Tail length1.64.910.4-2.6-1.5-3.03.2-2.4-2.4-3.2-2.1-2.5-2.2-0.8-2.3-2.02.0-2.3-1.83.1-2.6-1.2-0.40.5-2.01.2
Length with tail1.03.67.5-2.5-2.2-2.42.6-2.6-2.1-2.7-2.5-2.7-1.4-1.7-1.7-1.51.5-1.7-1.32.7-1.9-0.2-0.00.7-0.3-0.3
Length without tail0.20.42.5-0.3-1.00.2-0.1-0.8-0.2-0.0-0.9-0.70.5-1.10.20.2-0.20.20.1-0.00.30.80.20.51.6-1.4
Times rat made contact with spout1.31.52.11.20.81.4-1.41.11.21.30.81.11.40.61.41.3-1.31.41.3-1.21.41.31.0-0.81.3-1.1
Lifetime Intake0.10.10.4-0.1-0.40.1-0.1-0.10.2-0.1-0.1-0.30.1-0.40.20.2-0.20.20.2-0.00.10.6-0.10.20.2-0.6
Liver weight, left1.32.04.41.40.42.0-2.11.21.42.00.60.81.50.11.51.0-1.01.61.5-1.91.41.41.1-0.62.0-1.7
Liver weight, right0.40.73.8-0.4-1.30.3-0.2-0.8-0.10.2-1.1-1.10.5-1.00.1-0.40.40.20.5-0.2-0.01.21.1-0.22.0-1.7
Locomotor activity0.71.14.11.12.00.4-0.51.81.00.21.81.5-0.01.80.70.6-0.60.70.4-0.30.7-0.60.1-1.0-1.31.4
Locomotor testing distance1.82.96.32.02.51.5-1.52.42.01.42.52.21.22.31.71.4-1.41.71.5-1.41.70.81.4-1.90.00.2
Locomotor testing rearing0.20.41.90.51.1-0.10.10.60.50.30.90.50.21.4-0.00.2-0.2-0.10.5-0.30.10.20.8-1.1-0.60.5
Locomotion in novel chamber0.20.20.7-0.4-0.5-0.20.2-0.6-0.50.2-0.5-0.8-0.30.1-0.4-0.80.8-0.3-0.2-0.1-0.6-0.20.4-0.3-0.20.4
Locomotion in novel chamber post-restriction0.10.10.60.20.40.1-0.20.40.10.40.50.2-0.20.5-0.20.2-0.2-0.3-0.1-0.3-0.2-0.5-0.40.1-0.80.7
Fecal boli incidents, locomotor time 11.21.44.9-1.4-2.0-0.70.6-1.6-1.2-1.3-1.8-1.3-0.6-2.2-0.3-0.20.2-0.4-0.91.3-0.4-0.0-0.91.70.9-1.1
Change in fecal boli incidents, locomotor task0.40.41.10.81.00.4-0.40.80.50.90.90.60.41.10.00.3-0.3-0.10.4-1.0-0.1-0.20.2-0.5-0.40.6
Time >=10cm from walls, locomotor time 12.42.55.11.71.71.2-1.21.61.81.81.41.21.92.00.81.2-1.20.72.1-1.70.91.92.1-2.31.2-1.2
Bouts of movement, locomotor time 10.10.10.5-0.3-0.2-0.40.4-0.3-0.3-0.5-0.7-0.6-0.1-0.1-0.2-0.00.0-0.30.10.5-0.30.10.6-0.20.0-0.3
Total resting periods, locomotor time 10.20.20.7-0.4-0.3-0.50.5-0.4-0.4-0.5-0.8-0.8-0.1-0.1-0.5-0.20.2-0.50.10.5-0.40.20.7-0.30.1-0.3
Rest time, locomotor task time 12.32.54.7-1.8-1.9-1.71.7-1.9-1.8-1.5-2.2-2.1-1.4-1.6-1.8-1.81.8-1.8-1.21.5-1.8-0.8-0.51.1-0.40.1
Distance moved, locomotor task time 11.51.73.31.51.61.3-1.31.61.61.21.81.61.11.51.41.2-1.21.41.2-1.21.30.90.7-1.30.5-0.2
Vertical activity count, locomotor time 10.40.41.90.61.10.3-0.30.90.70.51.41.20.11.10.40.4-0.40.40.2-0.50.4-0.1-0.3-0.4-0.60.7
Time >=10cm from walls, locomotor time 20.20.20.7-0.40.1-0.50.6-0.2-0.4-0.5-0.4-0.8-0.30.4-0.3-0.30.3-0.20.00.5-0.7-0.10.3-0.3-0.60.2
Bouts of movement, locomotor time 24.75.07.4-2.3-1.9-2.52.4-2.1-2.6-2.4-2.4-2.2-2.4-1.9-2.6-2.02.0-2.7-2.32.3-2.4-2.4-1.92.2-1.91.5
Total resting periods, locomotor time 25.66.08.5-2.5-2.3-2.62.4-2.3-2.8-2.4-2.7-2.4-2.6-2.4-2.8-2.22.2-2.9-2.62.3-2.5-2.6-2.32.6-1.91.5
Rest time, locomotor task time 22.02.37.1-1.6-2.6-0.80.7-2.0-1.7-0.6-2.4-2.0-0.9-2.7-1.4-1.41.4-1.4-1.20.8-1.3-0.7-1.12.00.7-0.7
Distance moved, locomotor task time 20.10.20.6-0.30.3-0.40.50.0-0.1-0.70.3-0.0-0.50.50.1-0.50.50.2-0.20.6-0.2-0.3-0.1-0.4-0.60.8
Vertical activity count, locomotor time 20.20.21.0-0.10.5-0.20.20.30.1-0.30.60.3-0.50.60.2-0.40.40.2-0.20.3-0.0-0.4-0.2-0.2-0.61.0
Light reinforcement 16.411.615.6-3.9-3.9-3.63.4-3.9-3.8-3.4-3.4-3.6-3.5-3.6-3.7-3.23.2-3.7-3.73.3-3.4-2.9-3.43.3-1.81.5
Light reinforcement 23.64.88.2-2.6-2.9-2.12.1-2.6-2.4-2.2-2.8-2.8-2.1-2.6-2.2-2.12.1-2.1-2.02.2-2.4-1.4-1.41.9-0.70.3
Bone: marrow area5.010.714.4-3.4-2.8-3.53.4-3.1-3.6-3.6-2.8-3.0-3.8-2.7-3.5-3.73.7-3.4-3.73.5-3.4-3.6-2.92.7-2.42.7
Bone: maximum diameter5.710.515.9-3.5-2.6-4.04.0-3.2-3.5-3.9-3.1-3.4-3.4-2.1-3.7-3.73.7-3.7-3.13.8-3.7-2.7-1.51.6-2.32.1
Bone: maximum force2.34.06.3-2.3-1.9-2.42.5-2.1-2.1-2.3-2.0-2.4-2.0-1.4-2.3-2.42.4-2.3-1.72.3-2.3-1.3-0.70.9-0.90.9
Bone: maximum moment1.83.25.0-2.0-1.7-2.12.2-1.9-1.9-2.1-1.8-2.2-1.8-1.3-2.1-2.22.2-2.0-1.52.0-2.1-1.2-0.60.9-0.70.7
Mean time between licks in bursts1.72.46.4-1.7-2.4-1.21.0-1.8-1.6-1.4-2.2-2.0-1.2-2.5-1.4-1.11.1-1.4-1.31.3-1.4-0.8-1.31.90.6-0.9
Mean num. licks in bursts3.34.05.32.01.52.2-2.11.92.11.81.41.72.31.22.32.1-2.12.32.3-1.72.32.32.1-1.72.1-1.9
Cd content in liver0.80.84.3-0.6-1.70.4-0.6-0.8-0.50.2-1.0-0.7-0.3-2.1-0.0-0.20.20.0-0.8-0.30.0-0.4-1.61.81.2-0.9
Co content in liver0.70.83.30.8-0.01.4-1.50.50.71.70.30.30.9-0.20.70.8-0.80.70.6-1.80.70.5-0.10.21.0-1.0
Cu content in liver0.20.32.00.40.60.2-0.10.30.30.30.20.00.60.90.20.1-0.10.20.8-0.30.20.71.4-1.20.3-0.1
Fe content in liver0.40.50.7-0.7-0.5-0.80.8-0.7-0.8-0.7-0.6-0.7-0.7-0.4-0.8-0.80.8-0.8-0.70.6-0.8-0.7-0.50.5-0.70.5
K content in liver1.91.85.2-1.2-0.0-1.91.9-0.7-1.2-1.8-0.4-0.8-1.60.4-1.5-1.31.3-1.5-1.11.8-1.5-1.3-0.3-0.3-2.31.9
Mg content in liver1.21.25.7-0.60.5-1.21.2-0.2-0.7-1.10.30.0-1.30.7-1.0-0.90.9-1.0-1.11.1-1.0-1.5-0.7-0.0-2.42.2
Mn content in liver0.20.20.8-0.3-0.2-0.30.3-0.3-0.0-0.6-0.4-0.40.2-0.20.20.4-0.40.10.30.70.10.80.4-0.20.8-0.9
Na content in liver3.33.58.2-1.6-0.1-2.62.7-1.1-1.6-2.5-0.6-1.1-2.10.4-2.1-1.81.8-2.1-1.62.4-2.1-1.8-0.50.2-2.92.7
Rb content in liver0.70.82.21.11.21.0-1.01.20.91.11.41.50.51.10.90.6-0.60.90.4-1.10.9-0.1-0.2-0.2-0.50.6
Se content in liver0.50.61.9-0.9-0.8-0.90.9-0.9-0.9-1.3-1.0-0.7-0.6-0.9-0.5-0.50.5-0.5-0.61.4-0.5-0.3-0.30.50.2-0.0
Sr content in liver0.40.31.00.21.0-0.30.40.60.3-0.50.80.7-0.31.00.10.1-0.10.10.10.70.1-0.20.4-0.9-0.90.9
Zn content in liver1.31.43.5-1.0-0.8-1.11.0-0.8-1.2-0.7-0.8-1.0-1.5-0.6-1.5-1.91.9-1.4-1.30.7-1.4-1.6-0.70.5-1.41.6
Bone: minimum diameter7.213.417.2-4.1-4.0-3.93.8-4.0-4.1-4.1-4.0-3.9-3.8-3.8-3.8-4.04.0-3.7-3.84.1-3.7-3.1-2.73.2-1.31.5
Time in familiar zone, hab. session 10.20.20.80.40.70.4-0.30.60.50.40.90.70.10.70.50.1-0.10.50.1-0.40.4-0.10.1-0.4-0.40.6
Time in novel zone, hab. session 10.20.20.8-0.1-0.60.2-0.2-0.3-0.10.2-0.5-0.30.3-0.6-0.00.4-0.4-0.10.0-0.3-0.00.3-0.40.60.6-0.9
Total zone transitions, hab. session 10.30.42.30.21.0-0.50.70.20.2-0.30.60.30.31.5-0.1-0.00.0-0.10.50.3-0.00.51.2-1.4-0.70.8
Total locomotion distance, hab. session 13.85.312.3-2.8-3.5-2.12.1-3.3-2.5-2.3-3.5-3.2-1.3-3.2-2.0-2.32.3-1.9-1.52.3-2.0-0.1-0.41.61.5-1.4
Locomotion velocity, hab. session 13.75.312.4-2.8-3.4-2.12.2-3.3-2.4-2.4-3.5-3.3-1.2-3.0-2.0-2.42.4-1.9-1.32.4-2.10.00.01.31.6-1.5
Time in familiar zone, hab. session 21.11.13.5-1.0-1.2-0.70.6-1.2-1.3-0.7-1.0-0.7-1.0-1.4-0.8-0.70.7-0.7-1.50.7-0.7-1.3-1.71.9-0.60.7
Time in novel zone, hab. session 20.50.51.20.70.80.5-0.50.90.90.50.70.50.70.90.50.6-0.60.51.0-0.60.40.90.9-1.10.3-0.6
Total zone transitions, hab. session 20.40.52.10.11.1-0.70.80.20.0-0.60.70.3-0.11.5-0.2-0.40.4-0.10.10.6-0.2-0.10.9-1.3-1.21.5
Total locomotion distance, hab. session 24.96.512.8-3.1-3.6-2.42.5-3.5-2.9-2.7-3.6-3.2-1.9-3.3-2.4-2.92.9-2.2-2.12.7-2.4-0.9-0.82.00.8-0.4
Locomotion velocity, hab. session 24.35.811.9-2.9-3.4-2.32.4-3.3-2.7-2.6-3.4-3.1-1.7-3.0-2.2-2.72.7-2.1-1.82.6-2.3-0.7-0.51.61.0-0.5
Novel to familiar place preference ratio0.50.51.6-0.60.1-0.90.9-0.0-0.3-0.90.2-0.4-1.10.2-0.9-0.50.5-0.9-0.70.8-0.9-0.9-0.80.2-1.31.1
Novelty place preference0.30.31.3-0.30.2-0.70.60.2-0.1-0.70.3-0.2-0.90.3-0.7-0.30.3-0.7-0.40.6-0.8-0.7-0.60.1-1.21.0
Time in novel zone, NPP test0.20.21.10.00.6-0.40.30.60.3-0.40.70.2-0.50.6-0.30.1-0.1-0.3-0.10.3-0.4-0.4-0.5-0.2-1.10.8
Total zone transitions, NPP test0.10.10.60.20.40.10.00.10.20.10.30.30.50.60.30.0-0.00.40.4-0.10.40.60.8-0.70.30.1
Total locomotion distance, NPP test4.46.117.6-2.8-4.2-1.51.5-3.5-2.6-1.8-3.8-3.3-1.2-4.1-1.8-2.42.4-1.7-1.71.7-1.8-0.2-1.02.52.3-1.9
Locomotion velocity, NPP test5.17.219.8-3.1-4.5-1.81.7-3.8-2.9-2.0-4.1-3.7-1.5-4.3-2.2-2.72.7-2.0-1.91.9-2.2-0.5-1.12.62.2-1.8
Intraocular pressure0.00.10.10.30.30.3-0.20.20.00.30.10.30.30.20.30.4-0.40.30.0-0.20.4-0.10.10.10.00.1
Delta distance traveled before/after self-admin3.33.56.9-1.7-1.2-1.91.8-1.4-2.0-1.8-1.5-1.2-2.3-1.2-2.0-1.91.9-2.0-2.11.8-2.1-2.5-1.91.6-2.62.0
Delta ambulatory time before/after self-admin1.71.93.5-1.2-1.1-1.31.2-1.1-1.5-1.2-1.3-0.9-1.6-1.2-1.5-1.21.2-1.5-1.61.3-1.5-1.9-1.61.4-1.91.2
Parametrial fat weight3.36.411.12.52.02.5-2.32.12.72.41.81.83.22.12.62.8-2.82.53.2-2.22.33.32.8-2.62.4-2.8
Pavlov. Cond. lever latency1.11.38.70.2-0.30.8-1.10.2-0.21.00.51.0-0.8-1.00.2-0.10.10.3-1.4-1.00.5-2.0-2.92.5-0.81.3
Pavlov. Cond. magazine entry latency1.01.34.6-0.8-0.8-0.81.0-1.2-0.4-1.0-1.4-1.50.7-0.2-0.4-0.10.1-0.40.91.0-0.61.92.2-1.21.5-2.0
Pavlov. Cond. change in total contacts2.22.46.9-1.5-2.0-1.31.4-2.0-1.1-1.4-2.5-2.60.2-1.3-1.1-0.80.8-1.10.31.3-1.41.61.8-0.51.9-2.3
Pavlov. Cond. index score1.11.48.2-0.4-0.1-0.71.0-0.60.1-0.9-0.9-1.20.90.5-0.10.1-0.1-0.11.40.9-0.42.22.9-2.11.4-1.9
Pavlov. Cond. latency score1.11.58.7-0.4-0.0-0.81.1-0.60.1-1.0-0.9-1.20.90.7-0.20.1-0.1-0.21.41.1-0.52.22.9-2.31.2-1.8
Pavlov. Cond. lever contacts1.01.26.6-0.50.0-1.11.4-0.6-0.1-1.3-0.9-1.20.50.7-0.5-0.10.1-0.51.11.3-0.71.72.6-2.10.6-1.3
Pavlov. Cond. magazine entry number0.91.15.9-0.0-0.10.1-0.30.3-0.40.30.50.6-1.2-0.6-0.4-0.50.5-0.4-1.4-0.3-0.1-2.2-2.41.7-1.41.9
Pavlov. Cond. intertrial magazine entries0.10.10.40.10.30.1-0.10.30.20.10.30.1-0.10.40.0-0.40.40.10.2-0.10.1-0.10.4-0.6-0.10.3
Pavlov. Cond. lever-magazine prob. diff.1.21.58.3-0.3-0.2-0.60.8-0.60.1-0.9-1.0-1.21.10.40.00.3-0.3-0.01.50.9-0.22.42.9-2.01.7-2.2
Pavlov. Cond. response bias0.91.13.6-0.8-0.9-0.70.9-1.1-0.4-1.0-1.4-1.50.5-0.4-0.4-0.20.2-0.40.71.0-0.61.61.8-0.91.4-1.9
Pavlov. Cond. lever latency0.91.26.0-0.7-1.5-0.0-0.2-0.7-0.9-0.3-1.0-0.6-0.9-2.1-0.4-0.40.4-0.4-1.30.2-0.4-1.3-2.42.40.2-0.2
Pavlov. Cond. magazine entry latency2.83.26.81.81.81.7-1.51.72.01.91.71.32.02.11.61.3-1.31.62.2-1.91.62.12.6-2.41.2-0.8
Pavlov. Cond. change in total contacts1.11.58.50.71.40.10.20.71.00.30.80.31.22.10.40.4-0.40.41.6-0.20.41.82.9-2.80.4-0.3
Pavlov. Cond. index score1.92.49.41.32.00.7-0.51.31.51.01.51.01.62.60.90.8-0.80.92.0-1.00.91.93.1-3.00.3-0.2
Pavlov. Cond. latency score1.51.98.01.21.70.6-0.41.11.30.91.30.81.42.30.80.6-0.60.81.8-0.90.81.72.8-2.70.3-0.1
Pavlov. Cond. lever contacts1.01.46.50.81.8-0.20.40.90.90.21.20.70.82.50.30.4-0.40.21.3-0.10.21.22.4-2.5-0.70.6
Pavlov. Cond. magazine entry number2.53.16.5-1.9-2.1-1.51.4-1.9-2.0-1.8-1.9-1.5-1.7-2.4-1.5-1.11.1-1.6-2.11.7-1.6-1.7-2.52.6-0.70.3
Pavlov. Cond. intertrial magazine entries0.60.81.8-0.9-0.5-1.31.3-0.8-1.0-1.2-0.8-0.9-0.9-0.3-1.1-0.60.6-1.2-0.71.2-1.2-0.7-0.50.4-1.10.5
Pavlov. Cond. lever-magazine prob. diff.1.72.18.61.31.90.6-0.41.21.40.91.40.91.52.50.90.8-0.80.91.9-0.80.81.82.9-2.80.2-0.2
Pavlov. Cond. response bias1.41.97.91.11.90.4-0.11.11.30.71.50.81.32.60.60.7-0.70.61.8-0.70.61.72.7-2.8-0.10.1
Time in closed arm before self-admin1.61.83.6-1.7-1.5-1.61.7-1.9-1.5-1.2-1.4-1.7-1.1-0.9-1.6-1.11.1-1.7-1.11.1-1.6-0.6-0.91.0-1.10.3
Time in closed arm after self-admin0.90.92.4-1.1-1.5-0.80.8-1.2-1.1-0.9-1.6-1.1-0.8-1.5-0.8-1.11.1-0.7-0.81.0-0.8-0.6-0.40.6-0.10.1
Time in open arm before self-admin0.70.81.91.00.41.3-1.41.00.91.00.50.80.8-0.21.10.5-0.51.20.7-0.81.30.50.6-0.41.4-0.6
Time in open arm after self-admin3.53.84.92.22.12.0-1.92.12.22.12.11.82.12.21.81.8-1.81.82.1-2.11.91.82.0-1.91.5-1.1
Bone: periosteal estimation6.613.618.7-4.1-3.4-4.34.3-3.9-4.0-4.3-3.6-3.9-3.9-2.9-4.1-4.24.2-4.0-3.74.3-4.0-3.1-2.32.4-2.12.1
Bone: periosteal perimeter4.06.79.2-2.9-2.6-3.03.0-2.9-2.9-3.0-2.8-2.9-2.5-2.3-2.9-3.03.0-2.8-2.43.0-2.8-1.9-1.31.7-1.11.1
Bone: post-yield work2.02.74.6-1.5-0.8-2.02.0-1.2-1.6-1.7-0.9-1.3-1.9-0.4-1.9-2.02.0-1.9-1.61.6-1.9-1.8-0.90.6-1.92.1
Progressive ratio test 1 active lever presses0.00.00.1-0.1-0.30.0-0.1-0.0-0.10.1-0.2-0.2-0.2-0.4-0.1-0.20.2-0.1-0.1-0.1-0.1-0.1-0.30.2-0.20.0
Progressive ratio test 1 breakpoint0.10.10.2-0.3-0.4-0.10.0-0.2-0.2-0.1-0.3-0.4-0.3-0.4-0.3-0.30.3-0.3-0.20.0-0.2-0.2-0.40.3-0.30.1
Progressive ratio test 1 inactive lever presses1.11.24.10.7-0.11.1-1.00.20.91.20.0-0.01.60.11.01.1-1.11.01.5-1.11.02.01.3-1.01.6-1.8
Progressive ratio test 2 active lever presses0.70.81.6-1.0-1.1-0.90.8-1.0-1.0-0.8-1.3-1.1-0.7-1.0-0.9-0.40.4-1.0-0.70.8-1.0-0.5-1.01.0-1.00.0
Progressive ratio test 2 breakpoint0.91.01.4-1.1-1.2-1.11.0-1.1-1.0-1.0-1.2-1.2-0.9-1.0-1.1-0.60.6-1.2-0.80.9-1.1-0.5-1.11.1-1.10.2
Progressive ratio test 2 inactive lever presses0.10.20.5-0.3-0.7-0.10.1-0.5-0.20.1-0.7-0.70.2-0.4-0.30.1-0.1-0.40.3-0.1-0.20.70.3-0.1-0.0-0.7
Incentive Sensitization - Responses1.01.02.2-1.1-0.8-1.31.2-1.0-1.0-1.2-1.1-1.0-0.9-0.6-1.1-0.30.3-1.3-0.81.1-1.3-0.6-1.01.0-1.50.1
Incentive Sensitization - Breakpoint0.91.02.0-1.1-0.8-1.21.2-1.0-1.0-1.1-1.1-1.0-0.9-0.6-1.1-0.30.3-1.3-0.71.0-1.2-0.5-1.01.0-1.40.1
Sum of active levers in priming session hrs 5-60.10.10.50.0-0.20.2-0.30.00.20.10.20.10.1-0.30.30.2-0.20.3-0.1-0.00.20.2-0.50.70.3-0.2
Progressive ratio0.30.41.1-0.8-0.5-0.90.9-0.7-0.6-1.0-0.8-1.0-0.5-0.4-0.6-0.00.0-0.7-0.31.0-0.8-0.1-0.20.4-0.4-0.2
Food seeking constrained by brief footshock0.20.20.6-0.40.1-0.70.8-0.20.0-0.7-0.1-0.4-0.10.6-0.40.2-0.2-0.60.30.6-0.40.60.8-0.7-0.3-0.2
Seeking ratio, punishment vs. effort0.10.10.40.30.30.2-0.20.30.40.30.50.40.20.40.2-0.00.00.20.3-0.30.50.40.6-0.60.40.1
Retroperitoneal fat weight5.718.727.84.23.14.7-4.53.64.54.22.93.05.13.04.94.1-4.15.05.1-4.14.45.35.0-4.34.7-4.4
Reaction time number correct0.20.30.70.50.30.6-0.80.60.40.40.50.70.1-0.10.50.7-0.70.5-0.1-0.50.4-0.3-0.80.70.1-0.0
Reaction time mean minus median0.30.41.1-0.5-0.0-0.60.7-0.4-0.4-0.2-0.0-0.5-0.60.5-0.7-1.01.0-0.6-0.30.1-1.0-0.40.2-0.5-1.01.1
Reaction time mean minus median AUC0.20.20.70.20.40.3-0.20.40.30.60.50.2-0.00.80.1-0.60.60.20.3-0.7-0.20.00.7-0.9-0.20.7
Reaction time num false alarms4.66.312.9-2.7-3.4-2.21.9-2.8-2.7-2.2-2.9-2.7-2.5-3.6-2.5-2.42.4-2.5-2.72.0-2.0-2.2-2.83.2-0.20.5
Reaction time num false alarms AUC3.65.09.6-2.3-2.7-1.91.7-2.3-2.3-2.0-2.1-2.1-2.4-3.0-2.3-2.12.1-2.3-2.71.8-1.7-2.3-3.03.1-0.71.0
Reaction time trials correct on left0.20.30.70.50.30.6-0.80.60.40.40.50.70.1-0.10.50.7-0.70.5-0.1-0.50.4-0.3-0.80.70.1-0.0
Reaction time trials on left0.20.30.80.40.30.6-0.70.60.40.40.50.70.0-0.10.50.7-0.70.5-0.1-0.40.4-0.4-0.90.80.00.0
Reaction time mean0.10.20.50.40.40.4-0.30.20.30.60.20.10.50.60.30.3-0.30.30.5-0.6-0.00.50.5-0.70.0-0.2
Reaction time mean AUC0.40.51.00.70.60.8-0.70.50.61.00.50.40.80.80.60.4-0.40.70.9-1.00.30.80.9-1.00.3-0.3
Median of all reaction times0.20.20.40.40.20.6-0.50.20.40.70.20.20.70.30.50.5-0.50.50.6-0.60.20.60.4-0.40.4-0.5
Reaction time omissions0.20.20.8-0.5-0.4-0.20.2-0.5-0.5-0.4-0.3-0.3-0.5-0.5-0.0-0.20.20.0-0.70.4-0.4-0.6-0.90.8-0.40.3
Reaction time false alarm rate2.02.85.0-1.8-2.2-1.51.4-1.8-1.8-1.4-1.8-1.8-1.6-2.2-1.8-1.81.8-1.8-1.81.3-1.3-1.5-1.71.9-0.20.5
Reaction time premature initiation rate0.60.83.6-0.80.1-1.31.5-0.7-0.7-1.8-0.5-0.4-0.60.4-0.4-0.60.6-0.3-0.31.9-0.60.00.7-1.1-0.80.6
Reaction time premature initiations0.20.21.7-0.30.3-0.70.8-0.2-0.3-1.2-0.10.1-0.30.30.10.1-0.10.2-0.11.3-0.10.00.3-0.6-0.50.3
Std. dev. reaction times0.20.31.70.20.80.00.10.40.30.40.70.1-0.01.30.0-0.30.30.10.3-0.5-0.3-0.00.7-1.2-0.90.9
Reaction time trials completed0.20.30.80.40.30.6-0.70.60.40.40.50.70.0-0.10.50.7-0.70.5-0.1-0.40.4-0.4-0.90.80.00.0
Reaction time trials AUC0.20.30.70.50.20.7-0.80.60.40.40.40.60.1-0.20.60.8-0.80.6-0.1-0.50.5-0.2-0.80.80.2-0.2
Run reversals in cocaine runway, females1.21.11.7-1.2-1.0-1.31.2-1.2-1.2-1.3-1.0-1.1-1.1-0.9-1.2-1.01.0-1.2-1.11.2-1.0-0.9-0.80.8-0.60.6
Run reversals in cocaine runway, males3.73.66.31.91.81.6-1.61.72.11.61.61.52.21.71.72.5-2.51.52.2-1.61.92.32.1-2.11.7-1.8
Latency to leave start box in cocaine runway7.17.710.6-3.1-2.7-3.33.2-2.9-3.0-3.0-2.6-2.7-3.0-2.3-3.2-3.03.0-3.2-2.82.7-2.8-2.3-2.02.2-2.01.9
Latency to leave start box in cocaine runway, F6.06.68.7-2.9-2.5-2.92.8-2.8-2.8-2.9-2.3-2.3-2.8-2.3-2.7-2.32.3-2.8-2.82.7-2.5-2.3-2.52.5-2.11.7
Latency to leave start box in cocaine runway, M1.61.54.7-1.3-1.2-1.41.3-1.1-1.1-1.1-1.1-1.3-1.3-0.9-1.7-2.22.2-1.6-1.00.9-1.0-0.90.00.3-0.31.0
Std. dev. time between licks in bursts2.63.14.8-1.8-1.3-1.81.8-1.5-1.8-1.7-1.1-1.4-2.2-1.2-1.9-2.12.1-1.8-2.11.6-1.8-2.2-1.81.7-1.71.8
Total sessions with >9 infusions0.10.20.8-0.4-0.8-0.1-0.0-0.2-0.1-0.4-0.4-0.4-0.4-0.9-0.1-0.30.3-0.0-0.20.3-0.2-0.0-0.60.6-0.1-0.2
Short access day 1 total inactive lever presses0.60.72.60.4-0.40.7-0.70.10.60.8-0.4-0.31.1-0.30.50.5-0.50.51.2-0.70.81.61.4-0.81.4-1.3
Short access day 10 total inactive lever presses1.21.44.30.7-0.31.3-1.10.00.61.5-0.5-0.31.6-0.00.90.6-0.61.01.5-1.31.01.92.1-1.41.9-1.4
Short access day 1 total infusions0.10.10.20.0-0.20.3-0.20.20.40.10.30.10.0-0.10.3-0.30.30.40.3-0.20.40.50.4-0.30.5-0.1
Short access day 10 total infusions0.00.10.2-0.4-0.4-0.30.3-0.3-0.1-0.4-0.2-0.4-0.2-0.2-0.1-0.10.1-0.0-0.00.2-0.20.3-0.00.1-0.1-0.1
Short access total infusions0.00.00.1-0.4-0.3-0.20.3-0.20.1-0.30.0-0.3-0.3-0.1-0.1-0.20.2-0.00.00.2-0.10.3-0.00.1-0.1-0.1
Short access day 1 locomotion1.11.22.7-1.5-1.6-1.21.2-1.6-1.2-1.1-1.4-1.5-0.9-1.3-1.1-0.70.7-1.1-0.91.0-1.1-0.3-0.91.1-0.70.1
Short access day 10 total locomotion1.61.82.5-1.5-1.3-1.41.4-1.4-1.5-1.2-1.2-1.3-1.6-1.1-1.4-1.51.5-1.4-1.41.2-1.4-1.4-1.01.1-1.21.3
Short access total locomotion2.62.74.0-2.0-1.8-1.81.7-1.8-1.7-1.7-1.4-1.6-1.9-1.5-1.6-1.61.6-1.6-1.81.6-1.6-1.3-1.71.7-1.41.2
One hour access (0.3 mA shock)0.10.20.6-0.3-0.8-0.10.0-0.5-0.20.1-0.5-0.7-0.0-0.7-0.30.1-0.1-0.3-0.2-0.0-0.30.2-0.60.8-0.0-0.5
Compulsive drug intake0.50.51.30.60.00.9-0.80.30.50.9-0.0-0.11.0-0.10.70.8-0.80.60.8-0.70.60.90.7-0.21.1-0.9
One hour access (shock baseline)0.40.50.9-0.8-0.7-0.70.6-0.7-0.7-0.7-0.6-0.7-0.8-0.7-0.7-0.60.6-0.7-0.70.6-0.7-0.6-0.90.8-0.80.4
Social response proportion2.73.05.82.11.62.3-2.32.11.82.41.71.81.61.31.71.3-1.31.81.6-2.31.90.81.2-1.41.1-0.5
Social responses0.40.61.80.80.90.7-0.81.30.80.81.31.3-0.10.70.3-0.20.20.40.1-0.70.9-0.70.0-0.5-0.11.1
Social time1.31.76.7-0.7-0.2-0.90.8-0.2-0.9-0.70.2-0.2-1.9-0.3-1.3-1.81.8-1.2-1.70.8-0.8-2.4-1.61.0-1.92.6
Soleus weight0.72.110.50.80.80.6-0.40.71.30.70.50.01.71.40.70.8-0.80.72.2-0.70.72.63.2-2.71.6-1.9
Bone: stiffness1.82.94.7-2.0-1.6-2.12.2-1.8-1.7-2.0-1.7-2.1-1.7-1.2-2.0-2.12.1-2.0-1.42.0-2.0-1.0-0.40.5-0.60.7
Tibialis anterior weight0.62.25.21.41.41.2-1.01.51.71.21.51.21.51.71.31.1-1.11.31.9-1.11.31.92.1-2.31.0-1.0
Time to tail flick, vehicle, before self-admin0.40.51.60.3-0.00.5-0.60.20.60.3-0.0-0.20.9-0.00.60.8-0.80.50.8-0.40.51.30.8-0.51.2-1.2
Time to tail flick, vehicle, after self-admin2.42.64.1-1.6-0.9-1.81.8-1.2-1.6-1.6-1.0-1.2-2.0-0.6-1.8-1.91.9-1.8-1.71.4-1.8-1.9-1.20.8-2.01.9
Time to tail flick, test, before self-admin3.02.96.7-1.5-0.4-2.02.1-0.9-1.5-1.8-0.3-0.6-2.3-0.0-1.9-1.81.8-1.9-1.91.6-1.8-2.3-1.61.0-2.62.5
Time to tail flick, test, after self-admin0.10.10.3-0.0-0.20.0-0.1-0.1-0.1-0.2-0.2-0.10.2-0.40.20.4-0.40.1-0.10.20.10.2-0.30.50.3-0.4
Delta time to tail flick, vehicle, before/after SA3.53.59.8-1.4-0.1-2.02.1-0.9-1.6-1.5-0.1-0.4-2.50.2-1.9-2.12.1-1.9-2.21.4-1.9-2.8-1.81.0-3.13.1
Delta time to tail flick, test, before/after SA0.70.62.60.3-0.40.7-0.80.00.30.3-0.4-0.31.0-0.80.81.1-1.10.80.6-0.30.71.10.10.41.6-1.6
Tibia length1.95.212.1-1.9-0.5-2.72.8-1.4-2.2-2.5-0.9-1.2-2.8-0.3-2.4-2.22.2-2.4-2.52.5-2.4-3.0-2.01.2-3.53.4
Ambulatory time before self-admin1.11.13.70.4-0.01.0-0.80.10.91.00.2-0.11.20.41.10.2-0.21.21.3-1.00.91.91.9-1.31.8-1.2
Ambulatory time after self-admin0.70.82.0-1.0-1.1-0.80.9-1.1-0.9-0.3-1.3-1.4-0.5-0.4-1.1-1.41.4-1.0-0.10.4-1.10.10.9-0.4-0.30.2
Bone: tissue strength1.41.44.11.31.90.8-0.71.81.31.01.91.60.42.00.70.4-0.40.80.9-1.00.80.00.7-1.4-1.01.3
Total heroin consumption0.30.41.20.40.70.5-0.40.60.7-0.00.60.70.40.61.00.5-0.51.10.7-0.00.50.80.8-0.60.4-0.3
Bone: trabecular number4.06.38.5-2.8-2.7-2.62.5-2.3-2.6-2.7-2.5-2.7-2.9-2.6-2.7-2.72.7-2.7-2.62.7-2.7-2.4-2.12.1-1.01.1
Bone: trabecular spacing2.73.55.22.22.31.9-1.81.91.92.12.12.22.02.22.02.1-2.11.91.8-2.11.91.41.2-1.50.1-0.3
Bone: trabecular thickness1.82.24.1-1.8-1.7-1.81.8-1.7-1.6-2.0-1.9-2.0-1.3-1.4-1.6-1.21.2-1.7-1.12.0-1.7-0.6-0.50.8-0.1-0.3
Bone: trabecular tissue density0.50.71.9-0.60.2-1.31.4-0.4-0.6-1.0-0.2-0.7-0.70.7-1.1-0.80.8-1.1-0.31.0-1.1-0.40.4-0.7-1.31.1
Water consumed over 24 hours0.60.71.20.80.70.9-0.90.90.90.70.80.90.80.61.00.8-0.81.10.8-0.61.10.80.8-0.80.9-0.5
Number of responses in last shaping day0.10.10.3-0.3-0.3-0.30.2-0.2-0.2-0.20.0-0.1-0.4-0.3-0.4-0.30.3-0.4-0.40.2-0.2-0.3-0.60.5-0.40.3