Hub : Genes

Neu2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr9_88264312_88264471 0.14 0.07 3.1e-07 0.03 0.06 0.06 0.05 3.1e-04 5.0e-08 1.0e-07 3.1e-06
2 NAcc gene expression Neu2 0.33 0.06 0.0e+00 0.3 0.45 0.45 0.45 1.3e-35 7.0e-58 2.6e-58 5.8e-58
3 Brain gene expression Neu2 0.36 0.13 0.0e+00 0.16 0.24 0.23 0.24 2.3e-14 1.1e-22 1.5e-21 2.4e-22
4 PL isoform ratio XM_006245361.4 0.08 0.04 3.8e-09 0.09 0.09 0.09 0.09 1.2e-09 1.2e-09 3.0e-10 9.0e-10
5 OFC gene expression Neu2 0.54 0.14 2.2e-07 0.17 0.26 0.2 0.2 8.4e-05 9.2e-07 1.9e-05 1.8e-05
6 NAcc mRNA stability Neu2 0.28 0.08 1.1e-16 0.16 0.16 0.16 0.16 1.5e-18 1.1e-18 1.2e-18 1.9e-18
7 Brain mRNA stability Neu2 0.15 0.07 5.0e-07 0.08 0.07 0.07 0.07 4.6e-08 2.8e-07 2.3e-07 1.8e-07
8 Brain isoform ratio XM_006245361.4 0.12 0.06 7.9e-08 0.06 0.09 0.09 0.09 1.4e-06 1.4e-08 2.6e-08 2.3e-08
9 NAcc intron excision ratio chr9_88180308_88232440 0.06 0.03 5.9e-07 0.05 0.06 0.05 0.05 1.9e-06 3.3e-07 1.1e-06 6.2e-07
10 PL gene expression Neu2 0.06 0.03 4.3e-05 0.01 0.04 0.03 0.03 1.0e-02 9.9e-06 8.2e-04 5.4e-04
11 Brain isoform ratio XM_039083110.1 0.18 0.1 1.4e-08 0.08 0.1 0.1 0.09 1.4e-07 3.9e-09 5.5e-10 8.6e-09
12 NAcc isoform ratio XM_039083110.1 0.18 0.1 1.4e-12 0.1 0.09 0.11 0.11 2.9e-11 2.1e-10 2.3e-12 1.2e-12
13 Adipose gene expression Neu2 0.05 0.03 7.1e-04 0.02 0.02 0.01 0.02 1.3e-03 5.9e-03 4.3e-02 4.9e-03
14 BLA isoform ratio XM_006245361.4 0.16 0.08 1.8e-06 0.04 0.09 0.07 0.07 2.4e-03 2.1e-05 1.8e-04 8.1e-05
15 PL isoform ratio XM_039083110.1 0.24 0.09 0.0e+00 0.19 0.19 0.18 0.17 2.6e-20 6.0e-21 8.3e-20 9.5e-19
16 Liver mRNA stability Neu2 0.03 0.02 1.8e-03 0.01 0.02 0.01 0.02 2.5e-02 5.8e-03 7.3e-03 3.6e-03
17 BLA gene expression Neu2 0.1 0.07 2.0e-03 0.05 0.04 0.03 0.05 8.4e-04 2.1e-03 1.2e-02 1.8e-03
18 BLA isoform ratio XM_039083110.1 0.22 0.09 6.3e-09 0.1 0.13 0.09 0.1 7.1e-06 2.8e-07 2.7e-05 3.1e-06
19 PL mRNA stability Neu2 0.1 0.05 3.7e-06 0.05 0.06 0.05 0.05 6.6e-06 3.8e-07 4.9e-06 3.0e-06
20 NAcc isoform ratio XM_006245361.4 0.04 0.03 6.8e-05 0.03 0.02 0.04 0.03 7.5e-05 8.2e-04 5.8e-05 1.4e-04
21 PL alternative TSS XM_039083110.1 0.07 0.04 9.1e-05 0.02 0.03 0.03 0.02 2.4e-03 5.8e-04 2.9e-04 1.1e-03
22 NAcc isoform ratio XM_017596302.2 0.03 0.02 5.0e-03 0.02 0.01 0 0.01 1.7e-03 1.6e-02 3.0e-01 5.7e-03
23 OFC mRNA stability Neu2 0.28 0.13 2.8e-03 0.08 0.13 0.16 0.06 6.7e-03 4.8e-04 1.6e-04 1.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.61.12.41.1-1.41.61.41.51.3-1.5-1.4-0.51.2-0.91.10.1-1.11.10.60.51.00.60.7-0.50.2-0.2
Area under the delay curve1.01.12.0-0.90.3-0.8-1.1-1.0-1.21.21.40.9-0.40.5-1.1-0.91.4-1.30.5-1.4-1.4-0.7-1.21.2-0.91.0
BMI with tail0.20.51.70.70.7-0.5-0.0-0.10.5-0.9-0.3-0.9-0.70.6-0.01.1-0.80.4-0.80.40.70.7-0.4-1.00.7-1.3
BMI without tail1.02.04.21.6-0.71.01.81.31.4-1.8-1.9-1.50.5-0.91.51.3-2.11.8-0.41.11.90.91.3-1.60.5-1.6
Body weight0.41.89.83.1-1.71.31.51.11.3-1.9-1.6-2.20.2-1.20.61.6-1.30.90.41.61.0-0.40.8-0.4-0.3-0.2
Weight adjusted by age0.70.85.4-1.70.5-0.1-0.70.10.00.20.51.70.71.1-0.1-1.40.6-0.40.8-2.3-0.30.9-0.90.20.40.2
Bone surface0.81.54.02.0-1.71.71.71.51.4-1.9-1.6-1.20.9-0.91.00.7-1.31.10.41.21.10.20.8-0.4-0.2-0.1
Bone volume0.81.33.41.6-1.61.61.51.51.5-1.9-1.5-0.91.0-0.71.10.5-1.21.10.31.21.10.50.9-0.60.2-0.3
Breakpoint value in progressive ratio session0.30.31.60.6-0.4-0.00.5-0.3-0.60.5-0.1-0.7-0.2-1.20.10.7-0.10.10.30.6-0.1-1.00.60.2-1.00.4
Number of licking bursts1.21.44.41.80.7-1.2-0.2-1.2-1.00.30.2-2.1-1.90.2-1.12.1-0.2-0.3-1.52.0-0.2-1.5-0.20.2-1.0-0.1
Context. condit. distance diff. score0.60.71.5-0.51.0-1.2-1.1-1.2-1.21.01.10.1-1.10.5-1.10.20.8-0.9-0.70.2-0.9-0.7-0.40.5-0.50.3
Locomotion velocity, session 10.20.20.50.1-0.60.70.50.70.4-0.5-0.40.20.7-0.50.4-0.4-0.20.30.3-0.10.30.30.30.00.40.0
Locomotion distance, session 10.10.20.60.6-0.2-0.1-0.1-0.4-0.40.20.2-0.4-0.4-0.4-0.50.40.3-0.40.00.3-0.4-0.80.00.6-0.60.6
Locomotion velocity, session 21.11.34.3-1.41.1-1.4-1.1-1.5-1.92.11.50.6-1.00.3-1.1-0.31.3-1.1-0.60.4-1.2-1.1-0.40.9-0.90.7
Locomotion distance, session 20.10.20.80.9-0.70.60.20.30.4-0.4-0.2-0.30.3-0.90.00.00.1-0.10.40.3-0.1-0.30.30.30.30.6
Locomotion velocity, session 30.30.30.90.4-0.50.60.50.70.9-0.9-0.6-0.10.5-0.30.6-0.1-0.50.50.3-0.10.60.70.4-0.50.9-0.5
Locomotion distance, session 30.30.30.90.5-0.50.1-0.5-0.1-0.0-0.00.50.2-0.00.0-0.6-0.40.8-0.90.7-0.5-0.8-0.6-0.70.8-0.11.0
Stereotopy head waving bouts, day 30.10.20.40.10.5-0.6-0.2-0.6-0.70.60.3-0.3-0.60.0-0.60.40.2-0.3-0.4-0.2-0.3-0.5-0.30.4-0.30.1
Stereotopy head waving duration, day 30.50.61.40.4-0.80.91.20.90.7-0.6-1.0-0.20.8-1.21.1-0.1-0.81.00.5-0.40.90.50.8-0.60.6-0.4
Locomotion velocity, session 70.30.41.3-0.8-0.80.70.60.60.00.2-0.20.91.0-0.70.7-1.00.10.21.1-0.8-0.00.20.10.1-0.30.4
Locomotion distance, session 70.91.24.20.9-2.11.71.71.30.5-0.6-1.1-0.21.4-2.01.2-0.4-0.50.81.6-0.00.4-0.30.90.1-0.50.7
Stereotopy head waving bouts, day 70.70.82.0-1.41.3-1.2-1.3-1.0-0.81.11.20.9-0.71.3-0.8-0.50.8-0.8-0.4-1.0-0.70.0-1.00.30.1-0.0
Stereotopy head waving duration, day 70.91.13.3-1.81.8-1.4-1.5-1.1-0.60.91.31.1-0.81.8-0.8-0.50.8-0.8-0.9-0.8-0.60.5-1.10.00.6-0.4
Locomotion velocity, session 80.81.03.2-0.6-0.50.3-0.9-0.10.00.30.91.40.60.4-0.7-1.41.4-1.21.5-1.8-1.2-0.2-1.11.2-0.21.4
Locomotion distance, session 80.20.31.1-0.1-0.70.7-0.20.60.7-0.60.00.90.8-0.30.1-1.00.4-0.30.9-0.5-0.30.4-0.10.30.80.6
Degree of sensitization distance1.41.44.20.7-1.31.42.01.30.7-0.7-1.6-0.71.1-1.81.60.4-1.41.60.41.01.30.31.7-0.9-0.2-0.5
Degree of sensitization stereotypy1.01.13.3-1.71.8-1.5-1.5-1.2-0.91.11.31.0-0.91.8-0.9-0.40.8-0.8-0.8-0.7-0.60.3-0.90.10.2-0.3
Conditioned locomotion0.91.13.21.40.00.01.20.20.2-0.6-1.1-1.8-0.5-1.00.61.7-1.41.2-0.91.51.2-0.11.3-1.0-0.0-1.1
Cocaine response after cond. corrected1.51.74.3-0.11.6-1.8-1.4-1.8-1.61.01.3-0.6-2.01.4-1.71.00.8-1.1-2.11.4-0.9-1.1-0.60.8-0.90.1
Cocaine response after cond. not corrected0.80.95.70.11.3-1.2-0.5-0.8-0.5-0.00.3-0.8-1.31.2-0.61.2-0.3-0.0-2.41.70.20.00.2-0.40.1-0.9
Cocaine response before conditioning2.12.54.40.9-1.01.61.91.92.1-2.0-2.1-0.61.4-1.02.00.4-2.02.00.10.52.11.61.6-1.91.6-1.6
Saline control response2.22.88.22.6-2.11.72.91.50.7-1.2-2.3-2.30.8-2.31.51.5-1.91.80.51.61.5-0.71.8-0.6-1.3-0.2
Bone: connectivity density0.10.21.20.4-0.1-0.10.2-0.2-0.60.30.0-0.5-0.3-0.3-0.30.5-0.0-0.0-0.10.6-0.1-0.7-0.00.3-1.10.4
Bone: cortical apparent density0.20.31.1-0.60.9-0.4-0.8-0.10.3-0.30.30.4-0.31.0-0.3-0.10.1-0.2-1.10.10.00.7-0.3-0.30.8-0.4
Bone: cortical area2.63.98.61.9-2.52.62.92.62.0-2.3-2.7-1.31.9-1.92.30.5-2.32.30.81.62.10.92.2-1.30.1-0.7
Bone: cortical porosity0.50.52.6-1.5-0.10.4-0.40.30.30.30.41.60.90.60.2-1.50.7-0.40.5-1.0-0.40.6-0.40.30.30.5
Bone: cortical porosity0.70.73.1-1.5-0.50.8-0.10.80.50.00.11.81.40.50.5-1.70.5-0.11.0-1.2-0.20.8-0.40.30.10.6
Bone: cortical thickness1.11.94.10.6-1.61.92.01.91.4-1.4-1.9-0.41.6-1.21.8-0.1-1.61.80.50.91.60.91.5-1.00.0-0.6
Bone: cortical thickness0.10.20.7-0.0-0.30.10.70.0-0.50.4-0.3-0.40.1-0.60.30.3-0.30.50.30.30.3-0.40.6-0.0-0.9-0.0
Bone: cortical tissue density0.20.31.5-0.41.0-0.6-0.8-0.30.1-0.20.40.2-0.50.9-0.50.10.1-0.3-1.20.2-0.00.6-0.3-0.20.7-0.4
Condit. Reinf. active minus inactive responses0.30.31.30.2-0.00.30.60.40.2-0.4-0.7-0.50.2-0.50.60.5-0.80.8-0.41.10.80.30.8-0.70.3-0.6
Condit. Reinf. active-inactive response ratio0.30.32.30.4-0.10.30.60.40.3-0.6-0.6-0.50.1-0.30.40.5-0.70.6-0.71.50.70.30.6-0.50.3-0.5
Condit. Reinf. active responses0.10.10.4-0.60.10.0-0.20.10.1-0.00.10.60.30.1-0.0-0.50.2-0.10.20.1-0.00.3-0.10.00.30.1
Condit. Reinf. inactive responses0.70.82.8-1.70.4-0.3-1.1-0.2-0.20.50.91.70.41.1-0.4-1.51.0-0.80.6-1.6-0.80.5-0.90.60.10.6
Incentive salience index mean0.10.10.4-0.2-0.30.50.00.50.5-0.5-0.20.40.60.00.3-0.5-0.00.10.40.00.10.5-0.1-0.10.50.1
Condit. Reinf. lever presses0.81.03.6-1.2-0.30.6-0.80.50.8-0.40.51.81.11.0-0.1-1.90.9-0.71.3-1.9-0.60.8-1.20.60.70.7
Condit. Reinf. active minus inactive responses0.81.02.1-1.0-0.3-0.0-0.8-0.3-0.60.81.01.30.40.9-0.8-1.31.3-1.11.1-1.4-1.2-0.4-1.11.3-1.01.4
Condit. Reinf. active-inactive response ratio0.60.71.9-0.1-0.60.1-0.4-0.3-0.60.70.70.50.20.4-0.7-0.71.0-0.91.2-1.1-1.0-0.8-0.81.3-1.31.4
Condit. Reinf. active responses0.50.72.5-1.2-0.70.7-0.10.50.10.30.31.51.20.50.2-1.60.7-0.41.2-1.5-0.50.3-0.60.7-0.60.9
Condit. Reinf. inactive responses0.20.31.2-1.1-0.20.50.10.60.4-0.2-0.11.10.90.20.5-1.00.10.10.2-0.60.10.7-0.2-0.10.40.1
Condit. Reinf. lever presses0.70.93.80.8-1.91.71.11.20.7-0.7-0.80.11.4-1.20.7-0.6-0.10.31.8-0.60.1-0.20.00.6-0.81.0
Condit. Reinf. lever reinforcers received0.71.02.9-1.2-0.70.5-0.30.2-0.30.60.61.51.00.6-0.2-1.61.1-0.71.4-1.7-0.9-0.1-0.91.2-1.01.3
Conditioned reinforcement - actives0.90.94.2-1.40.90.0-1.10.41.4-0.60.31.40.51.50.5-1.10.10.0-0.5-0.40.21.7-0.5-1.02.0-0.9
Conditioned reinforcement - inactives0.10.20.90.9-0.3-0.0-0.2-0.30.1-0.00.2-0.6-0.40.1-0.20.50.2-0.40.20.7-0.4-0.7-0.20.3-0.40.3
Conditioned locomotion0.80.93.4-1.70.80.1-0.30.61.1-0.4-0.21.30.80.51.1-1.0-0.40.7-0.3-0.60.71.80.5-1.31.6-1.4
Patch foraging indifference point 0 sec1.93.07.92.5-1.51.02.60.80.1-0.6-2.1-2.8-0.0-2.81.42.2-2.01.90.12.51.6-0.92.4-0.8-1.1-0.7
Patch foraging indifference point AUC0.40.52.21.5-0.20.10.50.20.5-0.8-0.7-1.3-0.4-0.90.31.3-0.90.6-0.10.20.6-0.00.2-0.60.0-0.7
Delay disc. indifference point, 0s delay0.91.02.5-1.11.1-1.1-1.6-1.1-0.80.91.40.9-0.71.4-1.1-0.61.2-1.2-0.4-1.0-1.1-0.2-1.20.7-0.00.5
Delay disc. indifference point, 16s delay0.90.92.0-0.10.0-0.5-0.9-0.9-1.01.01.10.4-0.5-0.1-1.2-0.51.3-1.30.6-0.9-1.4-1.2-1.11.4-1.11.3
Delay disc. indifference point, 2s delay0.80.91.8-1.30.9-0.9-1.2-0.9-0.80.81.31.2-0.41.3-1.0-0.81.2-1.1-0.3-1.0-1.0-0.1-1.30.9-0.20.6
Delay disc. indifference point, 24s delay0.20.20.6-0.5-0.30.40.50.3-0.00.3-0.10.50.6-0.80.8-0.6-0.00.30.8-0.80.00.10.2-0.1-0.40.2
Delay disc. indifference point, 4s delay0.90.92.4-1.30.5-0.7-1.1-0.8-1.01.21.31.2-0.20.4-0.9-1.01.3-1.10.5-1.6-1.2-0.3-1.11.0-0.60.8
Delay disc. indifference point, 8s delay1.31.43.00.00.3-1.2-1.0-1.5-1.71.41.4-0.0-1.20.2-1.5-0.01.4-1.50.0-0.4-1.5-1.6-1.01.5-1.61.0
Indifference point function ln k0.20.21.0-1.00.00.30.10.50.5-0.1-0.20.80.60.70.5-0.8-0.10.30.10.40.30.80.3-0.50.7-0.2
Indifference point function log k0.20.21.0-1.00.00.30.10.50.5-0.1-0.20.80.60.70.5-0.8-0.10.30.10.40.30.80.3-0.50.7-0.2
Patch foraging total patch changes 0 sec2.23.59.02.7-1.20.92.70.90.3-0.9-2.2-3.0-0.1-2.81.42.5-2.32.1-0.32.81.9-0.72.5-1.2-0.8-1.1
Patch foraging total patch changes 12 sec0.91.25.12.0-0.3-0.31.0-0.5-0.80.3-0.6-2.3-1.1-1.90.02.1-0.90.6-0.10.90.4-1.40.8-0.0-1.5-0.3
Patch foraging total patch changes 18 sec3.13.910.13.1-2.11.63.11.30.5-1.3-2.5-3.00.4-3.21.72.3-2.42.20.41.81.9-0.82.5-0.9-1.2-0.8
Patch foraging total patch changes 24 sec3.13.714.23.8-3.02.22.71.71.1-1.8-2.3-2.70.8-3.11.21.6-1.71.41.71.41.2-1.11.5-0.1-1.30.4
Patch foraging total patch changes 6 sec0.91.35.82.4-0.70.31.20.20.1-0.6-1.1-2.4-0.6-1.80.42.0-1.20.9-0.01.60.8-0.90.9-0.2-0.9-0.4
Patch foraging time to switch 0 sec0.71.12.5-0.40.1-0.7-0.7-1.1-1.61.51.20.4-0.6-0.1-1.1-0.31.3-1.20.3-0.6-1.4-1.5-0.41.6-1.51.5
Patch foraging water rate 0 sec1.21.94.50.30.10.71.31.21.3-1.1-1.7-0.80.6-0.61.70.9-2.02.0-0.91.52.01.41.3-2.11.3-1.9
Patch foraging water rate 12 sec0.30.51.20.7-1.01.10.81.11.1-0.9-0.9-0.20.9-0.50.7-0.2-0.60.60.60.20.60.40.3-0.40.5-0.0
Patch foraging water rate 18 sec1.11.53.00.3-0.31.01.11.51.7-1.6-1.5-0.30.90.01.50.1-1.61.6-0.30.51.71.70.9-1.61.6-1.5
Patch foraging water rate 24 sec2.94.08.5-0.3-1.52.52.02.92.8-2.2-2.40.62.7-0.52.8-1.0-2.02.40.80.22.42.61.4-2.02.1-1.4
Patch foraging water rate 6 sec1.11.63.60.6-1.61.91.61.91.8-1.6-1.7-0.11.7-0.61.7-0.4-1.21.41.0-0.21.41.10.8-1.00.8-0.6
Seeking ratio, delayed vs. immediate footshock0.30.31.6-0.20.3-0.3-0.8-0.3-0.20.30.70.2-0.30.7-0.9-0.30.6-0.70.1-0.4-0.7-0.3-1.30.6-0.10.7
Distance traveled before self-admin0.20.21.10.9-0.30.00.1-0.1-0.2-0.2-0.0-0.7-0.30.3-0.30.6-0.0-0.10.20.4-0.2-0.7-0.10.4-1.00.5
Distance traveled after self-admin0.20.21.00.4-0.50.10.1-0.1-0.30.30.2-0.2-0.0-0.2-0.30.00.3-0.30.50.4-0.4-0.70.00.7-1.00.7
Extensor digitorum longus weight0.31.23.5-1.1-0.90.6-0.60.2-0.30.60.81.61.00.6-0.4-1.91.4-1.11.4-1.0-1.2-0.3-1.31.5-1.11.8
Bone: elastic displacement0.30.31.11.1-0.70.50.70.30.2-0.4-0.6-0.80.0-1.00.40.5-0.50.4-0.20.90.3-0.30.6-0.20.1-0.1
Bone: elastic work1.21.63.70.3-1.61.91.31.91.9-1.7-1.50.31.8-0.51.6-0.8-1.01.20.8-0.01.21.40.8-0.91.2-0.5
Bone: endosteal estimation1.12.46.81.9-2.52.41.72.32.3-2.6-1.9-0.51.8-0.61.4-0.2-1.21.21.60.11.20.90.8-0.40.5-0.0
Bone: endosteal perimeter1.43.07.22.7-2.22.12.41.91.9-2.3-2.4-1.81.2-1.81.71.0-1.91.70.81.41.70.31.7-1.10.5-0.6
Epididymis fat weight0.30.82.51.30.3-0.10.70.10.3-0.7-0.8-1.5-0.6-0.70.41.6-1.10.8-1.01.50.90.00.7-0.90.2-0.9
Delta time in closed arm before/after self-admin0.40.41.30.40.6-0.60.1-0.3-0.2-0.2-0.3-0.9-0.80.30.01.1-0.70.4-0.91.10.60.10.1-0.70.3-0.9
Delta time in open arm before/after self-admin0.90.81.8-0.8-0.2-0.1-0.7-0.5-0.71.01.01.10.2-0.2-0.7-1.31.4-1.10.9-0.9-1.3-0.7-0.61.3-0.91.3
Diff in mean of infusions in LGA sessions0.60.63.0-0.71.4-0.8-1.1-0.40.3-0.10.50.3-0.61.7-0.40.10.1-0.3-1.30.40.00.8-0.9-0.61.4-0.6
Delay discount exponential model param1.01.01.80.9-0.40.81.11.01.2-1.2-1.3-0.90.4-0.51.10.8-1.41.2-0.41.31.30.71.1-1.20.9-1.0
Extinction: sum of active levers before priming2.42.45.41.6-1.31.42.21.51.3-1.5-2.1-1.70.8-2.31.81.4-2.02.00.31.21.90.41.9-1.40.2-1.0
Active lever presses in extinction session 60.30.31.3-0.51.2-0.8-0.6-0.6-0.40.40.4-0.1-0.70.9-0.30.40.0-0.2-0.90.0-0.00.10.3-0.10.1-0.3
Bone: final force5.18.223.01.2-4.34.83.04.54.2-3.8-3.11.04.6-1.43.1-2.2-1.72.13.5-1.71.92.51.0-0.61.30.4
Bone: final moment5.79.226.11.3-4.65.13.24.84.4-4.0-3.30.94.8-1.63.4-2.2-1.92.33.7-1.72.12.51.1-0.71.20.5
Food consumed during 24 hour testing period0.60.72.11.4-1.41.30.81.11.2-1.3-0.9-0.50.8-0.70.50.0-0.50.31.00.10.40.10.20.00.40.4
Glucose0.60.92.60.20.9-0.80.8-0.5-0.60.3-0.6-1.3-0.9-0.70.51.6-1.21.1-1.11.01.1-0.01.2-1.2-0.1-1.5
Heart weight0.81.23.70.6-0.5-0.3-0.7-0.8-1.00.71.00.0-0.50.5-1.4-0.21.4-1.50.7-0.3-1.5-1.5-0.91.9-1.61.8
Delay discount hyperbolic model param1.41.42.51.1-0.61.01.31.21.4-1.5-1.6-1.00.6-0.61.30.8-1.61.5-0.41.41.60.91.4-1.41.1-1.1
Intermittent access intake day 1-15 change0.60.61.2-0.90.0-0.4-0.7-0.6-0.81.10.91.00.00.9-0.5-0.91.1-0.90.6-0.7-1.0-0.6-0.51.0-1.10.7
Intermittent access intake escalation0.80.81.7-1.30.2-0.4-0.9-0.6-0.81.21.01.30.11.1-0.7-1.11.2-0.90.6-1.0-1.0-0.4-0.61.0-1.00.8
Intermittent access intake escalation 20.30.30.9-0.40.1-0.4-0.4-0.5-0.70.90.60.3-0.20.2-0.4-0.20.6-0.50.30.0-0.6-0.6-0.10.6-0.90.5
Intermitt. access day 1 inactive lever presses2.12.38.83.0-0.8-0.60.5-1.1-1.20.4-0.0-2.7-1.8-1.8-0.82.4-0.1-0.4-0.32.6-0.5-2.50.50.8-2.00.5
Intermitt. access day 15 inactive lever presses1.51.74.50.3-0.8-0.3-0.8-1.0-1.41.41.30.2-0.4-0.3-1.1-0.61.7-1.71.4-0.6-1.9-1.9-1.31.9-1.82.1
Intermitt. access escalation Index1.71.57.02.5-2.61.51.30.80.5-1.1-0.8-1.10.6-1.50.30.3-0.1-0.02.00.8-0.2-1.20.20.9-1.51.2
Intermittent access day 1 total infusions1.41.65.00.3-0.11.00.61.42.2-1.7-1.3-0.20.9-0.41.70.2-1.41.4-0.10.21.51.80.6-2.02.1-1.6
Intermittent access day 15 total infusions0.30.41.6-0.4-0.30.7-0.00.81.3-0.7-0.40.50.80.40.9-0.5-0.40.50.5-0.30.51.0-0.1-0.70.7-0.5
Intermittent access terminal intake (last 3 days)0.80.93.00.3-0.91.30.71.31.7-1.4-1.00.01.1-0.31.4-0.2-0.80.90.9-0.00.81.00.2-1.00.8-0.6
Intermittent access total infusions0.91.03.00.9-1.01.20.81.21.7-1.4-1.1-0.50.9-0.91.50.3-1.01.00.80.30.90.70.4-1.10.7-0.8
Intermittent access day 1 locomotion1.51.64.80.60.8-0.00.50.41.3-1.1-1.0-1.1-0.3-0.81.31.4-1.61.4-1.31.41.51.10.9-2.21.7-2.2
Intermittent access day 15 total locomotion0.30.30.80.70.3-0.0-0.10.10.8-0.4-0.4-0.7-0.30.10.50.8-0.60.4-0.40.70.50.30.5-0.80.4-0.9
Intermittent access total locomotion0.80.92.31.00.00.20.60.30.9-0.6-0.9-1.2-0.2-1.31.11.2-1.11.0-0.41.01.00.31.2-1.40.7-1.5
Intermittent access standard deviation0.40.41.1-0.30.9-0.9-0.8-1.0-0.81.10.8-0.1-0.90.3-0.60.40.5-0.5-0.60.1-0.6-0.6-0.20.2-0.60.0
Left kidney weight0.61.66.11.3-0.3-0.7-0.7-1.1-1.30.81.0-0.9-1.20.4-2.00.81.1-1.40.30.4-1.4-2.0-1.11.9-2.51.7
Right kidney weight0.71.96.12.2-0.4-0.7-0.4-1.2-1.40.70.7-1.7-1.5-0.2-1.91.40.8-1.3-0.01.1-1.3-2.4-0.61.7-2.51.5
Cocaine induced anxiety0.70.83.51.0-0.81.10.61.21.5-1.9-1.0-0.40.70.20.80.1-0.80.7-0.11.20.80.90.3-0.71.0-0.4
Post-drug Anxiety0.60.71.70.5-0.91.11.01.11.0-1.3-1.1-0.20.9-0.60.8-0.0-0.90.90.30.60.90.81.0-0.50.6-0.4
Baseline Anxiety0.50.51.9-0.3-0.90.61.00.3-0.60.7-0.40.20.7-1.40.3-0.4-0.00.41.2-0.90.1-0.51.20.6-1.30.5
Tail length1.23.59.73.1-2.72.12.81.61.0-1.5-2.4-2.41.0-3.01.71.5-1.81.71.01.71.4-0.82.5-0.5-0.80.0
Length with tail0.62.310.93.3-2.81.81.70.90.5-0.9-1.3-2.00.6-2.50.51.0-0.50.31.61.20.0-1.71.30.9-1.41.4
Length without tail0.40.83.31.1-1.71.00.30.40.3-0.2-0.0-0.00.7-0.7-0.3-0.50.6-0.61.8-0.5-0.8-0.9-0.41.3-0.91.6
Times rat made contact with spout1.21.34.30.7-2.12.01.01.71.6-1.4-1.00.41.8-0.51.1-1.0-0.40.51.9-1.00.40.6-0.10.10.40.6
Lifetime Intake1.11.34.1-0.1-0.61.30.61.52.0-1.4-1.10.31.4-0.51.8-0.4-1.01.20.8-0.41.11.50.3-1.41.3-1.0
Liver weight, left0.00.10.30.3-0.30.30.30.30.2-0.3-0.2-0.20.2-0.2-0.00.0-0.10.10.30.40.1-0.10.20.3-0.50.3
Liver weight, right0.20.31.01.0-0.90.80.60.80.9-1.0-0.7-0.40.5-0.30.30.1-0.50.40.8-0.20.40.30.2-0.10.1-0.0
Locomotor activity1.11.83.81.7-1.31.42.01.41.2-1.7-1.9-1.40.9-1.41.41.0-1.71.70.10.71.60.51.6-0.90.1-0.9
Locomotor testing distance0.50.82.31.1-1.21.21.51.00.5-0.8-1.3-0.90.8-1.21.00.6-1.01.10.30.40.9-0.11.2-0.2-0.6-0.1
Locomotor testing rearing0.10.10.20.00.3-0.3-0.3-0.4-0.50.40.3-0.1-0.30.4-0.40.30.2-0.2-0.50.1-0.2-0.3-0.10.4-0.40.2
Locomotion in novel chamber0.50.62.50.9-1.61.10.20.60.6-0.6-0.10.30.9-0.2-0.2-0.70.6-0.61.6-0.7-0.6-0.5-0.21.3-0.41.4
Locomotion in novel chamber post-restriction0.30.41.3-1.0-0.10.6-0.20.70.6-0.5-0.01.20.90.60.2-1.10.10.00.1-0.10.11.00.00.21.00.2
Fecal boli incidents, locomotor time 11.01.16.02.50.1-0.6-0.3-0.7-0.1-0.70.0-2.1-1.50.1-1.02.1-0.2-0.4-0.91.7-0.2-1.2-0.10.2-0.40.2
Change in fecal boli incidents, locomotor task2.32.29.8-3.10.10.3-0.80.50.30.70.93.11.61.10.3-3.01.1-0.51.3-2.8-0.61.4-1.20.30.70.5
Time >=10cm from walls, locomotor time 11.51.55.20.4-2.21.71.91.50.8-1.1-1.30.11.7-1.11.5-0.8-0.71.12.3-1.30.80.31.1-0.1-0.70.2
Bouts of movement, locomotor time 11.21.33.7-0.80.3-0.9-0.9-1.1-1.71.91.20.4-0.60.8-1.3-0.31.3-1.20.6-0.7-1.4-1.4-0.91.3-1.71.4
Total resting periods, locomotor time 10.30.42.1-0.0-0.2-0.30.0-0.5-1.11.20.3-0.3-0.3-0.0-0.50.20.4-0.30.5-0.0-0.5-1.1-0.10.5-1.50.7
Rest time, locomotor task time 10.60.63.80.1-0.80.10.5-0.4-1.21.20.3-0.20.0-0.9-0.3-0.20.5-0.40.9-0.3-0.7-1.4-0.10.9-1.91.2
Distance moved, locomotor task time 10.60.62.5-0.81.4-0.8-1.6-0.50.30.00.80.7-0.51.4-0.5-0.30.5-0.6-0.8-0.4-0.40.7-1.0-0.01.3-0.3
Vertical activity count, locomotor time 10.70.72.2-1.31.5-1.2-1.4-0.9-0.60.81.10.8-0.71.3-0.8-0.30.8-0.8-1.0-0.3-0.60.2-0.60.20.5-0.2
Time >=10cm from walls, locomotor time 20.80.92.6-0.7-1.31.31.21.10.3-0.3-0.80.81.6-1.01.4-1.0-0.40.91.3-0.90.60.50.8-0.3-0.6-0.1
Bouts of movement, locomotor time 21.51.63.1-0.60.1-0.9-1.0-1.3-1.71.51.50.7-0.60.6-1.6-0.71.7-1.60.6-1.3-1.7-1.4-1.21.8-1.71.5
Total resting periods, locomotor time 21.61.73.7-0.3-0.2-0.7-0.8-1.2-1.61.41.40.6-0.50.5-1.6-0.71.7-1.60.9-1.4-1.8-1.6-1.31.9-1.81.7
Rest time, locomotor task time 20.80.93.41.8-1.00.21.3-0.2-0.60.1-0.7-1.8-0.5-1.90.11.4-0.60.40.40.90.2-1.40.90.1-1.40.2
Distance moved, locomotor task time 20.60.73.0-1.61.3-0.7-1.4-0.4-0.00.40.81.1-0.11.7-0.3-0.70.5-0.4-0.4-0.6-0.40.7-1.0-0.10.6-0.1
Vertical activity count, locomotor time 22.22.47.8-2.72.8-2.1-2.2-1.6-1.41.71.91.5-1.22.3-1.2-0.61.1-1.0-2.1-0.1-0.80.5-1.00.10.5-0.5
Light reinforcement 11.93.58.51.6-0.81.12.41.41.2-1.5-2.4-2.00.5-2.22.01.8-2.62.5-0.72.42.40.82.9-2.00.6-1.9
Light reinforcement 22.63.47.61.70.50.11.40.61.2-1.7-1.9-2.3-0.6-1.01.32.5-2.52.1-2.12.62.41.12.4-2.51.6-2.8
Bone: marrow area1.12.36.51.9-2.42.41.72.22.3-2.5-1.9-0.61.8-0.61.4-0.2-1.31.21.50.21.20.90.8-0.50.4-0.0
Bone: maximum diameter2.64.88.91.6-1.62.12.92.42.2-2.4-3.0-1.61.5-1.92.81.0-2.92.9-0.12.02.81.52.7-2.41.1-2.0
Bone: maximum force5.39.124.52.1-4.55.03.34.74.6-4.6-3.50.24.4-1.63.3-1.5-2.22.43.1-0.72.42.51.3-1.01.60.0
Bone: maximum moment5.910.127.82.2-4.85.33.55.04.8-4.7-3.70.24.7-1.83.5-1.6-2.32.63.3-0.72.42.51.4-1.01.40.1
Mean time between licks in bursts0.71.02.1-0.20.7-1.0-1.3-1.2-1.01.21.30.3-0.90.3-1.4-0.11.3-1.4-0.2-0.1-1.4-1.0-1.11.2-0.71.0
Mean num. licks in bursts2.12.67.8-0.8-1.92.31.12.32.1-1.4-1.21.72.8-0.71.9-2.1-0.40.92.2-2.00.81.80.5-0.51.20.1
Cd content in liver0.40.51.00.3-0.1-0.4-0.6-0.6-0.70.50.7-0.1-0.5-0.0-0.8-0.00.8-0.9-0.1-0.2-1.0-1.0-0.81.0-1.01.0
Co content in liver0.40.50.90.90.10.20.50.40.7-1.0-0.8-0.9-0.2-0.40.40.9-1.00.8-0.90.80.90.50.4-0.80.6-0.9
Cu content in liver0.00.00.1-0.1-0.00.1-0.00.10.00.0-0.10.10.1-0.20.1-0.1-0.10.1-0.10.20.10.1-0.1-0.10.2-0.1
Fe content in liver0.30.40.9-0.60.8-0.8-0.9-0.7-0.70.70.80.4-0.60.5-0.8-0.10.6-0.7-0.3-0.3-0.6-0.3-0.80.5-0.50.2
K content in liver0.20.21.11.1-0.1-0.00.2-0.10.2-0.5-0.3-0.9-0.4-0.2-0.10.8-0.40.2-0.51.00.3-0.20.4-0.20.4-0.2
Mg content in liver1.21.22.71.1-0.40.71.20.80.9-1.2-1.4-1.20.2-0.81.11.0-1.41.3-0.71.61.40.51.4-1.20.9-1.1
Mn content in liver0.91.02.51.2-1.11.21.11.31.5-1.6-1.4-0.60.9-0.90.90.2-1.11.00.50.41.10.80.9-0.81.2-0.6
Na content in liver0.20.31.3-1.10.8-0.4-0.3-0.10.00.20.10.60.00.30.2-0.2-0.20.3-0.50.20.40.80.4-0.71.0-0.8
Rb content in liver0.60.81.9-1.10.2-0.3-0.9-0.4-0.60.71.01.20.11.4-0.7-1.11.1-1.00.2-0.9-1.0-0.2-1.21.0-0.60.9
Se content in liver0.40.62.40.6-1.31.00.30.60.5-0.4-0.20.30.9-0.9-0.1-0.70.4-0.31.6-0.9-0.4-0.3-0.60.9-0.51.1
Sr content in liver1.31.26.00.4-1.81.41.81.0-0.20.2-1.0-0.31.3-2.50.9-0.2-0.50.81.7-0.30.4-0.70.90.4-1.60.9
Zn content in liver0.30.30.8-0.50.00.40.40.50.5-0.4-0.50.30.6-0.30.9-0.3-0.50.7-0.1-0.00.70.90.2-0.90.8-0.9
Bone: minimum diameter1.83.36.42.1-2.42.52.52.42.2-2.5-2.5-1.21.8-1.52.00.5-2.02.00.81.51.90.81.8-1.00.3-0.6
Time in familiar zone, hab. session 11.11.14.8-0.01.6-1.1-0.2-0.7-0.30.1-0.1-0.9-1.30.30.01.5-0.80.6-2.21.70.80.30.5-1.30.8-1.7
Time in novel zone, hab. session 11.31.34.1-0.7-1.51.50.41.41.1-0.8-0.31.51.90.10.6-1.90.3-0.02.0-1.9-0.10.8-0.40.60.21.0
Total zone transitions, hab. session 10.50.82.70.9-1.61.50.81.31.3-1.2-0.80.11.3-0.60.6-0.6-0.20.21.3-0.60.20.30.10.30.30.7
Total locomotion distance, hab. session 12.73.810.53.0-3.22.92.62.52.2-2.5-2.5-1.51.9-2.71.70.4-1.61.52.10.01.40.11.4-0.30.10.3
Locomotion velocity, hab. session 12.43.310.33.2-3.22.72.32.22.1-2.4-2.2-1.51.7-2.51.40.5-1.31.12.10.01.0-0.11.10.00.00.6
Time in familiar zone, hab. session 24.14.311.5-3.22.6-2.1-3.3-1.7-1.11.52.72.6-0.93.4-2.0-1.62.2-2.1-0.9-1.8-1.80.7-2.71.00.50.5
Time in novel zone, hab. session 23.63.610.32.5-2.62.23.21.91.0-1.4-2.5-2.01.3-2.92.01.1-2.02.11.11.41.7-0.42.5-0.8-0.9-0.3
Total zone transitions, hab. session 20.40.62.10.9-1.30.80.30.30.0-0.1-0.0-0.10.5-0.6-0.3-0.30.5-0.51.3-0.8-0.7-0.9-0.21.2-1.11.4
Total locomotion distance, hab. session 21.52.07.42.2-2.72.02.01.30.5-0.7-1.3-1.21.2-2.30.80.3-0.60.62.1-0.10.2-1.20.70.9-1.71.4
Locomotion velocity, hab. session 21.31.76.02.4-2.51.71.81.00.3-0.6-1.2-1.40.9-2.20.50.5-0.50.41.8-0.00.1-1.30.70.9-1.71.3
Novel to familiar place preference ratio1.21.24.31.4-0.9-0.0-0.0-0.7-1.10.70.6-0.8-0.6-0.8-1.20.30.9-1.10.90.1-1.2-2.1-0.51.8-2.11.8
Novelty place preference1.31.44.61.1-0.7-0.3-0.2-0.9-1.41.00.8-0.7-0.7-0.8-1.30.31.0-1.20.9-0.0-1.4-2.1-0.61.9-2.11.9
Time in novel zone, NPP test1.31.44.21.0-0.7-0.2-0.3-0.8-1.20.90.8-0.4-0.5-0.6-1.40.01.2-1.31.0-0.3-1.5-2.0-0.82.0-2.12.0
Total zone transitions, NPP test0.91.25.21.6-2.31.70.81.11.0-0.9-0.6-0.01.3-1.40.4-0.70.3-0.32.1-1.0-0.4-0.60.01.0-0.21.6
Total locomotion distance, NPP test2.33.111.52.8-3.42.82.32.11.7-1.8-2.0-1.21.9-2.71.40.1-1.00.92.4-0.10.7-0.51.00.4-0.41.1
Locomotion velocity, NPP test2.33.311.82.9-3.42.82.42.11.7-1.8-2.1-1.21.9-2.81.50.1-1.01.02.5-0.20.8-0.51.20.3-0.31.0
Intraocular pressure0.40.61.8-0.21.0-0.70.4-0.4-0.60.4-0.3-0.9-0.80.00.21.1-0.80.8-1.11.30.70.01.1-0.8-0.4-1.0
Delta distance traveled before/after self-admin0.70.72.3-0.8-0.81.20.61.21.0-0.7-0.61.21.5-0.31.0-1.4-0.20.50.9-0.70.51.10.3-0.20.7-0.2
Delta ambulatory time before/after self-admin0.70.81.9-0.3-0.91.21.01.31.1-0.9-0.90.61.4-0.51.2-0.8-0.60.90.7-0.30.81.10.5-0.60.8-0.5
Parametrial fat weight0.51.03.21.40.3-0.90.3-1.0-1.30.50.0-1.8-1.5-0.6-0.71.8-0.3-0.0-0.91.3-0.1-1.40.30.3-1.6-0.1
Pavlov. Cond. lever latency0.20.31.30.8-0.90.80.40.81.0-1.1-0.5-0.10.6-0.20.2-0.1-0.20.10.6-0.10.20.40.00.00.60.2
Pavlov. Cond. magazine entry latency0.70.95.2-2.30.40.30.70.70.10.4-0.61.21.10.01.4-1.0-0.71.30.2-0.81.11.31.1-1.1-0.0-1.0
Pavlov. Cond. change in total contacts0.30.31.1-0.1-0.30.40.90.4-0.20.2-0.6-0.30.4-1.00.60.2-0.60.80.10.30.6-0.11.0-0.3-0.6-0.2
Pavlov. Cond. index score0.30.42.4-1.60.6-0.00.50.2-0.30.7-0.40.50.5-0.10.9-0.4-0.50.9-0.40.10.70.60.9-0.8-0.4-0.7
Pavlov. Cond. latency score0.40.52.0-1.40.50.00.60.3-0.20.5-0.50.40.5-0.11.0-0.3-0.71.1-0.50.10.90.71.0-1.0-0.3-0.9
Pavlov. Cond. lever contacts0.10.10.3-0.50.3-0.20.3-0.2-0.50.6-0.2-0.1-0.1-0.30.30.2-0.30.4-0.30.20.3-0.10.4-0.3-0.6-0.3
Pavlov. Cond. magazine entry number0.70.85.72.4-0.3-0.3-0.8-0.50.5-0.90.4-1.1-1.10.1-1.20.90.5-1.1-0.30.6-0.8-0.8-1.10.60.90.5
Pavlov. Cond. intertrial magazine entries1.61.94.60.30.4-1.2-1.8-1.5-1.11.01.80.2-1.30.9-2.1-0.21.8-2.10.2-0.5-2.0-1.5-2.01.8-0.81.6
Pavlov. Cond. lever-magazine prob. diff.0.40.52.6-1.60.50.10.60.3-0.20.5-0.40.60.6-0.01.0-0.4-0.61.0-0.40.10.80.71.0-0.8-0.2-0.8
Pavlov. Cond. response bias0.30.32.5-1.60.4-0.10.50.1-0.71.0-0.20.60.4-0.20.6-0.4-0.30.7-0.1-0.20.50.20.8-0.3-0.9-0.3
Pavlov. Cond. lever latency1.01.44.5-0.82.1-2.1-1.1-1.7-1.61.41.1-0.3-1.81.2-1.20.90.4-0.6-1.60.6-0.4-0.5-0.3-0.0-0.5-0.6
Pavlov. Cond. magazine entry latency0.10.10.40.6-0.0-0.2-0.6-0.30.0-0.20.4-0.1-0.40.1-0.60.10.5-0.6-0.10.1-0.6-0.4-0.40.40.30.3
Pavlov. Cond. change in total contacts0.20.31.00.3-1.00.90.10.70.7-0.7-0.20.50.90.10.2-0.70.2-0.20.9-0.7-0.20.2-0.50.4-0.10.6
Pavlov. Cond. index score0.40.52.30.9-1.51.20.40.80.8-0.7-0.40.21.0-0.90.2-0.60.2-0.21.4-0.5-0.3-0.2-0.20.6-0.01.0
Pavlov. Cond. latency score0.40.52.10.9-1.51.10.40.70.7-0.6-0.30.10.9-0.90.2-0.60.3-0.21.3-0.5-0.3-0.3-0.30.6-0.11.0
Pavlov. Cond. lever contacts1.21.65.51.2-2.32.31.41.91.6-1.6-1.4-0.01.9-1.51.3-0.7-0.60.71.7-0.40.60.40.40.00.20.6
Pavlov. Cond. magazine entry number0.10.10.2-0.20.10.10.30.20.10.0-0.3-0.10.1-0.20.40.0-0.40.4-0.30.20.40.20.4-0.30.0-0.3
Pavlov. Cond. intertrial magazine entries0.50.62.40.3-0.7-0.00.4-0.5-1.21.20.3-0.3-0.2-1.1-0.40.10.6-0.50.70.2-0.7-1.50.41.1-1.41.2
Pavlov. Cond. lever-magazine prob. diff.0.30.41.60.7-1.31.10.20.70.8-0.7-0.30.30.9-0.60.2-0.60.2-0.21.2-0.6-0.3-0.1-0.30.50.10.8
Pavlov. Cond. response bias0.91.34.11.1-2.02.01.11.71.6-1.5-1.20.11.7-1.01.1-0.7-0.50.61.5-0.50.50.50.4-0.00.40.5
Time in closed arm before self-admin2.32.68.9-2.10.00.1-1.8-0.10.10.71.62.91.01.3-0.9-3.02.2-1.81.2-2.6-1.80.4-1.61.60.21.6
Time in closed arm after self-admin1.01.04.3-1.0-0.50.6-0.70.40.7-0.40.61.91.11.1-0.2-2.11.1-0.81.1-1.7-0.80.7-0.60.80.50.8
Time in open arm before self-admin0.50.52.00.10.9-0.40.00.10.3-0.5-0.4-0.7-0.41.40.21.0-0.90.7-1.00.30.90.7-0.4-1.11.0-0.9
Time in open arm after self-admin0.10.20.4-0.30.6-0.6-0.4-0.5-0.60.70.3-0.2-0.50.3-0.40.40.1-0.2-0.4-0.1-0.2-0.3-0.70.0-0.30.1
Bone: periosteal estimation2.34.79.62.4-3.03.12.93.02.7-3.1-2.9-1.32.2-1.62.40.3-2.32.31.21.32.21.12.0-1.20.5-0.6
Bone: periosteal perimeter2.64.49.32.7-2.32.43.12.31.9-2.4-2.9-2.11.4-2.32.31.3-2.52.40.61.92.30.52.4-1.50.3-1.1
Bone: post-yield work1.62.17.22.1-2.12.21.52.12.4-2.7-1.8-0.71.6-0.71.20.0-1.21.11.10.51.20.90.7-0.50.9-0.1
Progressive ratio test 1 active lever presses0.30.31.10.6-0.10.30.20.41.1-0.8-0.5-0.50.0-0.20.70.5-0.60.5-0.00.20.60.6-0.0-1.00.8-0.9
Progressive ratio test 1 breakpoint0.50.51.21.1-0.40.40.60.51.1-1.1-0.7-0.90.0-0.50.80.8-0.80.70.00.60.70.40.2-1.00.5-0.9
Progressive ratio test 1 inactive lever presses0.70.82.30.50.8-1.2-1.0-1.3-0.91.01.0-0.7-1.50.6-1.00.90.7-0.9-0.81.2-0.9-1.1-0.60.3-0.40.2
Progressive ratio test 2 active lever presses0.30.31.3-0.40.6-0.1-0.80.21.0-0.60.10.40.01.00.4-0.2-0.10.0-0.3-0.20.21.0-0.6-0.81.2-0.8
Progressive ratio test 2 breakpoint0.30.31.2-0.20.7-0.3-0.9-0.10.8-0.40.30.2-0.31.00.20.0-0.0-0.1-0.50.00.00.7-0.7-0.71.1-0.8
Progressive ratio test 2 inactive lever presses0.10.10.50.1-0.20.3-0.50.20.7-0.40.20.20.20.20.4-0.20.2-0.20.4-0.0-0.20.1-0.5-0.20.50.1
Incentive Sensitization - Responses0.40.41.80.10.8-0.9-1.2-0.8-0.10.20.8-0.1-0.91.3-0.70.30.5-0.7-0.80.3-0.6-0.2-1.00.10.2-0.2
Incentive Sensitization - Breakpoint0.50.51.90.10.8-0.8-1.3-0.8-0.20.20.8-0.1-0.91.4-0.80.20.6-0.8-0.70.3-0.6-0.2-1.10.20.1-0.1
Sum of active levers in priming session hrs 5-60.30.32.21.0-0.60.40.50.10.2-0.1-0.4-0.7-0.0-1.50.20.5-0.20.20.30.70.1-0.51.20.0-0.10.1
Progressive ratio0.10.10.3-0.2-0.30.3-0.10.20.20.10.10.40.40.20.2-0.40.2-0.10.6-0.5-0.20.00.00.3-0.10.5
Food seeking constrained by brief footshock1.11.34.8-0.0-1.81.80.41.51.4-0.9-0.41.21.9-0.60.7-1.70.4-0.12.2-1.6-0.20.6-0.30.60.31.2
Seeking ratio, punishment vs. effort0.70.82.1-0.1-1.01.40.91.41.3-1.3-1.00.51.4-0.51.1-0.8-0.60.80.7-0.30.81.20.3-0.60.9-0.3
Retroperitoneal fat weight0.41.35.72.4-0.70.51.40.40.5-1.1-1.3-2.1-0.4-1.50.41.8-1.30.9-0.01.31.0-0.51.1-0.5-0.3-0.5
Reaction time number correct0.60.94.0-2.0-0.00.3-0.50.40.10.40.52.01.11.10.1-1.80.8-0.40.9-1.5-0.40.8-0.70.40.20.5
Reaction time mean minus median1.11.43.8-1.30.60.31.10.80.7-0.5-1.10.30.7-0.31.7-0.0-1.41.8-0.90.11.71.71.6-2.01.2-2.0
Reaction time mean minus median AUC0.71.02.3-1.10.10.60.90.90.8-0.6-0.90.61.0-0.11.5-0.4-1.01.4-0.2-0.51.31.51.1-1.51.0-1.3
Reaction time num false alarms0.50.72.81.7-0.50.31.00.30.2-0.7-0.9-1.6-0.3-0.50.31.4-1.00.7-0.31.40.7-0.40.7-0.2-0.4-0.3
Reaction time num false alarms AUC1.21.64.62.1-0.80.71.80.70.5-1.1-1.6-2.2-0.1-1.00.81.8-1.71.4-0.52.01.4-0.31.4-0.6-0.4-0.7
Reaction time trials correct on left0.60.94.0-2.0-0.00.3-0.50.40.10.40.52.01.11.10.1-1.80.8-0.40.9-1.5-0.40.8-0.70.40.20.5
Reaction time trials on left0.50.83.6-1.90.10.2-0.50.30.00.40.51.91.01.10.1-1.60.7-0.30.8-1.4-0.40.8-0.60.30.10.5
Reaction time mean0.71.03.2-1.61.1-0.40.40.20.00.2-0.50.30.1-0.11.10.1-1.01.3-1.60.71.21.31.4-1.70.9-1.8
Reaction time mean AUC1.21.64.6-1.20.60.31.10.80.6-0.5-1.10.10.6-0.61.80.1-1.51.8-1.30.71.81.61.9-2.21.2-2.1
Median of all reaction times0.60.83.5-1.41.4-0.8-0.1-0.4-0.40.60.00.2-0.40.10.50.2-0.50.7-1.90.90.70.81.0-1.30.7-1.5
Reaction time omissions1.41.85.80.11.5-1.00.7-0.5-0.3-0.1-0.9-1.5-1.2-0.10.62.1-1.61.5-2.41.71.60.51.7-2.00.7-2.3
Reaction time false alarm rate1.82.58.62.9-0.80.51.90.50.4-1.2-1.8-2.9-0.6-1.50.82.6-1.91.5-0.92.61.5-0.61.7-0.9-0.4-0.9
Reaction time premature initiation rate0.50.64.1-2.01.1-0.7-0.7-0.4-0.40.70.71.30.01.0-0.3-0.80.4-0.2-0.6-1.1-0.10.8-0.6-0.20.4-0.3
Reaction time premature initiations0.91.28.1-2.80.9-0.4-0.9-0.1-0.30.90.92.30.71.5-0.2-1.70.8-0.40.0-1.8-0.41.1-0.90.10.30.1
Std. dev. reaction times0.91.34.6-1.51.2-0.30.70.30.2-0.1-0.80.20.10.11.30.3-1.31.6-1.50.41.61.61.6-2.01.1-2.1
Reaction time trials completed0.50.83.6-1.90.10.2-0.50.30.00.40.51.91.01.10.1-1.60.7-0.30.8-1.4-0.40.8-0.60.30.10.5
Reaction time trials AUC0.60.83.6-1.8-0.10.3-0.50.3-0.00.50.61.91.01.10.0-1.70.9-0.51.0-1.4-0.60.6-0.80.6-0.00.7
Run reversals in cocaine runway, females0.50.52.4-0.50.10.4-0.40.71.2-1.2-0.10.80.60.90.3-0.8-0.10.1-0.3-0.50.31.3-0.3-0.41.6-0.5
Run reversals in cocaine runway, males0.50.52.6-1.60.00.3-0.00.40.20.40.11.41.00.30.6-1.30.20.20.4-1.00.10.80.5-0.20.2-0.1
Latency to leave start box in cocaine runway0.70.83.40.90.1-0.20.8-0.3-0.50.3-0.6-1.5-0.6-1.30.31.5-0.80.8-0.71.80.6-0.71.4-0.6-0.6-0.5
Latency to leave start box in cocaine runway, F0.90.93.20.90.6-0.30.5-0.10.1-0.3-0.8-1.6-0.8-0.70.41.8-1.21.0-1.11.81.10.00.8-1.30.4-1.3
Latency to leave start box in cocaine runway, M0.70.62.41.1-1.00.30.9-0.1-0.70.4-0.3-0.9-0.1-1.5-0.00.6-0.00.10.50.7-0.2-1.41.00.7-1.50.8
Std. dev. time between licks in bursts0.20.21.3-0.1-0.30.20.4-0.1-0.60.7-0.0-0.10.1-1.20.1-0.00.10.10.40.3-0.2-0.70.30.5-1.10.6
Total sessions with >9 infusions1.61.85.8-1.30.30.80.41.31.9-1.3-0.91.11.30.51.8-0.9-1.11.30.1-1.01.42.40.2-2.02.0-1.8
Short access day 1 total inactive lever presses2.22.55.2-0.40.7-1.2-2.1-1.6-1.31.62.10.8-1.11.6-2.3-0.72.2-2.30.4-1.0-2.3-1.4-1.82.0-1.11.9
Short access day 10 total inactive lever presses1.71.97.32.7-0.9-0.40.7-1.0-1.40.5-0.1-2.4-1.5-1.4-0.82.1-0.0-0.30.11.9-0.5-2.50.60.9-2.00.8
Short access day 1 total infusions1.31.44.4-1.70.40.7-0.61.11.8-0.9-0.11.81.41.01.1-1.7-0.10.40.5-1.70.42.1-0.6-1.01.8-0.7
Short access day 10 total infusions0.80.93.20.6-0.91.20.71.21.8-1.3-1.0-0.11.0-0.81.5-0.1-0.80.90.8-0.10.80.90.4-1.10.9-0.8
Short access total infusions1.61.85.5-1.30.21.00.21.52.1-1.3-0.81.21.50.21.8-1.1-0.91.20.4-1.31.22.30.1-1.82.1-1.5
Short access day 1 locomotion2.32.57.7-2.1-0.31.3-0.41.51.9-1.0-0.12.72.21.21.3-2.80.30.21.3-2.80.22.4-0.8-0.72.1-0.3
Short access day 10 total locomotion1.71.98.02.00.7-1.00.3-1.0-0.50.1-0.4-2.6-1.9-1.4-0.12.8-1.00.6-1.52.60.5-1.20.9-0.9-0.5-1.2
Short access total locomotion1.01.03.60.60.7-0.20.50.20.8-0.6-0.8-1.2-0.5-0.71.11.4-1.31.2-1.01.31.20.60.9-1.81.0-1.9
One hour access (0.3 mA shock)1.31.53.8-0.5-0.21.00.61.41.9-1.5-1.20.41.2-0.01.8-0.4-1.31.40.2-0.31.51.90.6-1.71.7-1.5
Compulsive drug intake0.40.51.8-0.41.3-0.9-0.7-0.5-0.20.10.3-0.1-0.80.9-0.50.5-0.2-0.0-1.30.30.20.4-1.1-0.60.9-0.7
One hour access (shock baseline)1.01.12.60.8-1.51.51.11.41.6-1.3-1.2-0.31.2-1.11.6-0.1-0.91.01.20.30.80.60.9-0.80.3-0.4
Social response proportion5.45.913.01.50.40.72.11.62.2-2.6-2.8-2.20.1-1.02.52.3-3.53.2-2.02.63.42.22.9-3.52.5-3.6
Social responses1.21.64.8-0.20.70.20.90.71.0-0.8-1.3-0.60.2-0.51.60.8-1.81.8-1.10.81.81.41.4-2.21.4-2.1
Social time0.81.12.6-0.70.40.50.61.01.2-0.7-1.00.30.8-0.41.4-0.1-1.21.4-0.5-0.51.41.60.9-1.61.6-1.4
Soleus weight0.20.73.01.50.1-0.20.6-0.2-0.2-0.2-0.6-1.7-0.8-0.5-0.11.7-0.90.6-0.91.50.6-0.60.8-0.4-0.7-0.6
Bone: stiffness2.13.39.31.2-2.73.01.72.93.0-3.0-1.90.42.7-0.31.8-1.2-1.11.21.9-0.61.21.70.5-0.41.10.2
Tibialis anterior weight0.20.84.1-0.70.4-0.3-1.3-0.20.4-0.20.91.20.02.0-0.8-1.01.0-1.10.1-1.0-0.80.5-1.70.70.40.5
Time to tail flick, vehicle, before self-admin0.60.62.2-0.20.7-0.7-1.1-0.7-0.40.50.90.4-0.61.5-1.1-0.20.9-1.0-0.4-0.3-0.9-0.3-1.30.60.20.5
Time to tail flick, vehicle, after self-admin0.20.21.4-0.10.7-0.5-0.2-0.4-0.50.50.1-0.4-0.60.3-0.40.6-0.1-0.0-0.91.20.0-0.30.30.1-0.50.0
Time to tail flick, test, before self-admin1.21.22.80.1-1.01.41.01.51.7-1.3-1.20.51.5-0.81.5-0.7-0.81.00.7-0.61.01.30.9-0.91.6-0.6
Time to tail flick, test, after self-admin0.50.51.40.9-0.90.90.80.91.2-1.1-0.9-0.30.6-0.50.80.1-0.70.70.20.20.70.60.5-0.60.7-0.5
Delta time to tail flick, vehicle, before/after SA0.80.83.00.40.3-0.21.0-0.1-0.50.4-0.8-1.2-0.4-1.40.61.4-1.01.0-0.81.70.9-0.31.6-0.7-0.8-0.8
Delta time to tail flick, test, before/after SA0.10.10.20.30.1-0.20.1-0.1-0.20.1-0.0-0.4-0.3-0.0-0.20.5-0.20.1-0.40.40.1-0.1-0.0-0.1-0.3-0.1
Tibia length2.16.015.21.3-3.63.92.83.63.4-2.9-2.80.43.6-2.13.0-1.5-1.62.03.3-1.41.81.81.5-0.91.1-0.0
Ambulatory time before self-admin0.20.21.50.8-0.50.20.50.0-0.2-0.0-0.3-0.8-0.1-0.40.10.6-0.20.20.50.20.0-0.70.60.2-1.20.4
Ambulatory time after self-admin0.50.63.30.6-0.7-0.00.1-0.5-0.90.90.4-0.4-0.3-0.6-0.60.20.6-0.60.90.3-0.8-1.50.01.1-1.81.1
Bone: tissue strength6.15.916.00.1-2.93.61.63.74.0-3.3-2.21.73.8-0.52.6-2.4-1.11.52.8-2.41.63.00.5-1.12.6-0.2
Total heroin consumption0.30.30.9-0.4-0.70.70.20.40.1-0.0-0.00.80.9-0.20.1-1.00.4-0.20.9-0.6-0.3-0.10.60.7-0.60.7
Bone: trabecular number0.10.20.50.1-0.20.40.70.40.1-0.2-0.6-0.30.3-0.60.60.4-0.60.7-0.20.60.60.20.5-0.6-0.2-0.4
Bone: trabecular spacing0.50.71.9-0.60.5-0.6-1.4-0.6-0.10.31.10.9-0.41.3-1.0-0.81.1-1.2-0.1-0.8-1.00.0-1.00.70.60.5
Bone: trabecular thickness0.70.81.81.3-0.81.01.30.90.8-1.1-1.3-1.10.4-0.80.80.9-1.21.0-0.11.01.00.10.7-0.5-0.2-0.4
Bone: trabecular tissue density1.52.07.8-1.6-1.21.5-0.51.31.3-0.80.32.62.21.10.3-2.81.0-0.62.0-2.2-0.61.3-1.21.00.31.3
Water consumed over 24 hours2.42.96.31.1-1.92.42.02.52.5-2.4-2.2-0.42.0-0.92.2-0.3-1.81.91.1-0.11.91.61.2-1.31.4-0.7
Number of responses in last shaping day1.41.44.1-2.01.0-0.8-1.5-0.7-0.71.01.51.8-0.12.0-0.8-1.61.4-1.2-0.1-1.1-1.20.3-1.40.70.30.7